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SMAD4

SMAD family member 4
General Information
Name SMAD family member 4
Alias
  • mothers against decapentaplegic homolog 4
  • MAD homolog 4
  • SMAD, mothers against DPP homolog 4
  • deleted in pancreatic carcinoma locus 4
  • deletion target in pancreatic carcinoma 4
  • mothers against decapentaplegic, Drosophila, homolog of, 4
Gene_family SMAD family
organism Homo sapiens
entrez_id 4089
location 18q21.2
transcript_count 6
exon_count 14
Location
by NCBI GRCh38.p14
Summary
    Entrez This gene encodes a member of the Smad family of signal transduction proteins. Smad proteins are phosphorylated and activated by transmembrane serine-threonine receptor kinases in response to transforming growth factor (TGF)-beta signaling. The product of this gene forms homomeric complexes and heteromeric complexes with other activated Smad proteins, which then accumulate in the nucleus and regulate the transcription of target genes. This protein binds to DNA and recognizes an 8-bp palindromic sequence (GTCTAGAC) called the Smad-binding element (SBE). The protein acts as a tumor suppressor and inhibits epithelial cell proliferation. It may also have an inhibitory effect on tumors by reducing angiogenesis and increasing blood vessel hyperpermeability. The encoded protein is a crucial component of the bone morphogenetic protein signaling pathway. The Smad proteins are subject to complex regulation by post-translational modifications. Mutations or deletions in this gene have been shown to result in pancreatic cancer, juvenile polyposis syndrome, and hereditary hemorrhagic telangiectasia syndrome. [provided by RefSeq, May 2022]
    Stringdb Mothers against decapentaplegic homolog 4; In muscle physiology, plays a central role in the balance between atrophy and hypertrophy. When recruited by MSTN, promotes atrophy response via phosphorylated SMAD2/4. MSTN decrease causes SMAD4 release and subsequent recruitment by the BMP pathway to promote hypertrophy via phosphorylated SMAD1/5/8. Acts synergistically with SMAD1 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. Binds to SMAD binding elements (SBEs) (5'-GTCT/AGAC-3') within BMP response element (BMPRE) of cardiac activating regions (By s [...]
    nextProt In muscle physiology, plays a central role in the balance between atrophy and hypertrophy. When recruited by MSTN, promotes atrophy response via phosphorylated SMAD2/4. MSTN decrease causes SMAD4 release and subsequent recruitment by the BMP pathway to promote hypertrophy via phosphorylated SMAD1/5/8. Acts synergistically with SMAD1 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. Binds to SMAD binding elements (SBEs) (5'-GTCT/AGAC-3') within BMP response element (BMPRE) of cardiac activating regions (By similarity). Common SMAD (co-SMAD) is the coactivator and mediator of signal transduction by TGF-beta (transforming growth factor). Component of the heterotrimeric SMAD2/SMAD3-SMAD4 complex that forms in the nucleus and is required for the TGF-mediated signaling (PubMed:25514493). Promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. Component of the multimeric SMAD3/SMAD4/JUN/FOS complex which forms at the AP1 promoter site; required for synergistic transcriptional activity in response to TGF-beta. May act as a tumor suppressor. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
SMAD4 BioGRID PRNP GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID TRIM67 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID SNIP1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
SMAD4 BioGRID CCNF GeneID BioGRID Proximity Label-MS
SMAD4 BioGRID DPF3 GeneID BioGRID Affinity Capture-Western
SMAD4 BioGRID USP15 GeneID BioGRID Affinity Capture-Western
SMAD4 BioGRID SMAD3 GeneID BioGRID Affinity Capture-Luminescence; Affinity Capture-MS; Affinity Capture-Western; Co-crystal Structure; FRET; PCA; Reconstituted Complex; Two-hybrid
SMAD4 BioGRID SMAD2 GeneID BioGRID Affinity Capture-Luminescence; Affinity Capture-MS; Affinity Capture-Western; Co-crystal Structure; Co-fractionation; Reconstituted Complex; Two-hybrid
SMAD4 BioGRID NCOA3 GeneID BioGRID Co-fractionation
SMAD4 BioGRID TCF3 GeneID BioGRID Co-fractionation
SMAD4 BioGRID RELA GeneID BioGRID Co-fractionation; Two-hybrid
SMAD4 BioGRID PDE6D GeneID BioGRID Co-fractionation
SMAD4 BioGRID PARP1 GeneID BioGRID Co-fractionation
SMAD4 BioGRID OVOL2 GeneID BioGRID Affinity Capture-Western
SMAD4 BioGRID ARID1B GeneID BioGRID Co-fractionation
SMAD4 BioGRID CREBBP GeneID BioGRID Affinity Capture-Western; Co-fractionation
SMAD4 BioGRID XRCC6 GeneID BioGRID Co-fractionation
SMAD4 BioGRID E2F4 GeneID BioGRID Co-fractionation
SMAD4 BioGRID RBM14 GeneID BioGRID Co-fractionation
SMAD4 BioGRID MED23 GeneID BioGRID Co-fractionation
SMAD4 BioGRID SMARCC2 GeneID BioGRID Co-fractionation
SMAD4 BioGRID SMARCC1 GeneID BioGRID Co-fractionation
SMAD4 BioGRID HGS GeneID BioGRID Affinity Capture-Western
SMAD4 BioGRID MYO18A GeneID BioGRID FRET
SMAD4 BioGRID GRIPAP1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID RIOK2 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID EXOC2 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID CNDP2 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID NLRP2 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID FERMT1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID FOXRED1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID CDC42BPG GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID ABHD10 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID QRSL1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID PGM2 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID VPS53 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID ELP2 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID UBA6 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID SBNO1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID MAP1S GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID SMG8 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID PRPF39 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID ERCC6L GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID MRPL50 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID PUS7 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID STK26 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID CHMP3 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID LSR GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID ANAPC7 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID HSPA14 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID SBDS GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID DCAF8 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID UBQLN1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID DPP7 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID TFCP2L1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID MRPL18 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID MCTS1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID GIT1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID CHMP2A GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID ARFIP1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID SNX5 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID DNAJC2 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID HERC4 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID DPCD GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID CAPG GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID BAX GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID ATP5ME GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID ALDH1A3 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID AKT1 GeneID BioGRID Affinity Capture-Western; Co-localization
SMAD4 BioGRID AP1G1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID PARP4 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID ACOX1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID ACADSB GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID TRIM72 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID EIF2AK4 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID TICAM2 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID HECTD4 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID TTC9C GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID EML3 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID RICTOR GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
SMAD4 BioGRID STXBP4 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID PDE12 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID EXOC8 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID KLC3 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID MTCL2 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID UBLCP1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID DIS3L2 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID CCDC43 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID SLC38A10 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID EARS2 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID PDZD8 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID ARAP1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID OSBPL11 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID ARHGAP18 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID DMKN GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID METTL18 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID BTF3L4 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID PSME4 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID METAP1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID PDXDC1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID TRAPPC8 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID TWF2 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID AKAP11 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID PKP3 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID GLMN GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID OGFR GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID MLLT11 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID AP3M2 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID EHD1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID MALT1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID USP19 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID SEC24A GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID PAIP1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID ARFGEF1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID UBE4B GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID ARPC1B GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID HDAC6 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID GNPDA1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID WASHC5 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID TELO2 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID UBE3C GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID LPIN2 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID ROCK2 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID ARHGAP29 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID KIF3B GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID NHERF1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID UBE4A GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID TRIP10 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID TBRG4 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID NEMF GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID SORD GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID SKIL GeneID BioGRID Affinity Capture-Luminescence; Affinity Capture-MS; Affinity Capture-Western; Two-hybrid
SMAD4 BioGRID SKI GeneID BioGRID Affinity Capture-Luminescence; Affinity Capture-MS; Affinity Capture-Western; Co-crystal Structure; Reconstituted Complex; Two-hybrid
SMAD4 BioGRID S100A2 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID ROCK1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID RNPEP GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID PTK7 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID PTK2 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID PTGFRN GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID DNAJC3 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID PKN1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID PRKAA1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID PREP GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID PIK3R2 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID PGM3 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID PFKFB2 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID NDUFV1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID PPP1R12A GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID MMUT GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID MTR GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID ND2 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID MTIF2 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID ABCC1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID SMAD9 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Two-hybrid
SMAD4 BioGRID PLXNB2 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID LARS2 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID NCSTN GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID SRGAP2 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID USP24 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID DNMBP GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID EXOC6B GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID NFS1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID HIP1R GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID SUCLG2 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID EIF3J GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID ASMTL GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID PPFIBP1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID STK24 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID WFS1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID UQCRB GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID UBE3A GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID TXNRD1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID TST GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID TRAF6 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID SYPL1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID SUPV3L1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID STRN GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID STAT2 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID ST14 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID SPR GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID SMAD4 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SMAD4 BioGRID LLGL2 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID LAMB2 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID ITGA3 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID ITGA6 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID INPPL1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID HMGCS2 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID HK2 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID GSS GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID GPD2 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID GNL1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID GBE1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID GAA GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID MTOR GeneID BioGRID Affinity Capture-MS; Negative Genetic
SMAD4 BioGRID FDXR GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID MARK2 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID DOCK1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID DAD1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID CYP24A1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID CRAT GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID CPT2 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID CPD GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID CDH3 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID LHX4 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID GTPBP10 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID TUBGCP6 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID LRCH3 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID MRPL43 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID CMSS1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID ASCC2 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID MAGT1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID ITCH GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID ILKAP GeneID BioGRID Affinity Capture-MS; Co-fractionation
SMAD4 BioGRID CYB5B GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID AARSD1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID FLAD1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID CDK5RAP3 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID PTGES2 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID NAA25 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID THNSL1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID ZFAND1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID HECTD3 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID FYCO1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID PDCL3 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID PCYOX1L GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID DDRGK1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID EPS8L2 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID MTMR14 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID HEATR6 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID CELA2A GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID GUF1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID OSTC GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID MIER1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID DOCK6 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID FZR1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID USP13 GeneID BioGRID Co-localization
SMAD4 BioGRID UCHL1 GeneID BioGRID Affinity Capture-Western; Co-localization
SMAD4 BioGRID KDF1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID CIC GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID CCDC180 GeneID BioGRID Two-hybrid
SMAD4 BioGRID TSTD2 GeneID BioGRID Two-hybrid
SMAD4 BioGRID MSANTD3 GeneID BioGRID Two-hybrid
SMAD4 BioGRID AOPEP GeneID BioGRID Two-hybrid
SMAD4 BioGRID HEMGN GeneID BioGRID Two-hybrid
SMAD4 BioGRID STX17 GeneID BioGRID Two-hybrid
SMAD4 BioGRID ZNF510 GeneID BioGRID Two-hybrid
SMAD4 BioGRID SMAD1 GeneID BioGRID Affinity Capture-Luminescence; Affinity Capture-Western; Co-fractionation; Two-hybrid
SMAD4 BioGRID HRAS GeneID BioGRID Two-hybrid
SMAD4 BioGRID FANCC GeneID BioGRID Two-hybrid
SMAD4 BioGRID LAMTOR5 GeneID BioGRID Two-hybrid
SMAD4 BioGRID FBP2 GeneID BioGRID Two-hybrid
SMAD4 BioGRID CDC14B GeneID BioGRID Two-hybrid
SMAD4 BioGRID ZNF189 GeneID BioGRID Two-hybrid
SMAD4 BioGRID SHC1 GeneID BioGRID Two-hybrid
SMAD4 BioGRID SFRP4 GeneID BioGRID Two-hybrid
SMAD4 BioGRID SFRP2 GeneID BioGRID Two-hybrid
SMAD4 BioGRID PPP3R2 GeneID BioGRID Two-hybrid
SMAD4 BioGRID PPP2CB GeneID BioGRID Two-hybrid
SMAD4 BioGRID BAAT GeneID BioGRID Two-hybrid
SMAD4 BioGRID ALDOB GeneID BioGRID Two-hybrid
SMAD4 BioGRID MED26 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID MEN1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID USP10 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
SMAD4 BioGRID E6 GeneID BioGRID PCA; Two-hybrid
SMAD4 BioGRID ETV4 GeneID BioGRID Two-hybrid
SMAD4 BioGRID TLE5 GeneID BioGRID Two-hybrid
SMAD4 BioGRID NFKBID GeneID BioGRID Two-hybrid
SMAD4 BioGRID LMO4 GeneID BioGRID Two-hybrid
SMAD4 BioGRID ZIC1 GeneID BioGRID Two-hybrid
SMAD4 BioGRID UBE2I GeneID BioGRID Affinity Capture-Western; Two-hybrid
SMAD4 BioGRID USP7 GeneID BioGRID Affinity Capture-Western
SMAD4 BioGRID ezh2.L GeneID BioGRID Co-localization
SMAD4 BioGRID HDAC1 GeneID BioGRID Affinity Capture-Western
SMAD4 BioGRID EZH2 GeneID BioGRID Affinity Capture-Western
SMAD4 BioGRID PLEKHA4 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID TRIM47 GeneID BioGRID Affinity Capture-Western; Co-localization
SMAD4 BioGRID H4C1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID APEX1 GeneID BioGRID Affinity Capture-RNA
SMAD4 BioGRID HDAC2 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID TP63 GeneID BioGRID Positive Genetic
SMAD4 BioGRID HYAL2 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
SMAD4 BioGRID WWOX GeneID BioGRID FRET; Two-hybrid
SMAD4 BioGRID DCP1A GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SMAD4 BioGRID RELB GeneID BioGRID Affinity Capture-Western
SMAD4 BioGRID KDM1A GeneID BioGRID Affinity Capture-Western
SMAD4 BioGRID HMG20A GeneID BioGRID Affinity Capture-Western; Two-hybrid
SMAD4 BioGRID USP4 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
SMAD4 BioGRID SMURF2 GeneID BioGRID Affinity Capture-Western
SMAD4 BioGRID TRIM25 GeneID BioGRID Affinity Capture-RNA
SMAD4 BioGRID USP9X GeneID BioGRID Affinity Capture-Western
SMAD4 BioGRID AHR GeneID BioGRID Affinity Capture-Western
SMAD4 BioGRID COPS5 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SMAD4 BioGRID TRIM33 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
SMAD4 BioGRID WEE1 GeneID BioGRID Negative Genetic
SMAD4 BioGRID CDK9 GeneID BioGRID Negative Genetic
SMAD4 BioGRID NANOG GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID SMAD7 GeneID BioGRID Affinity Capture-Western; Phenotypic Suppression; Reconstituted Complex
SMAD4 BioGRID DNMT3L GeneID BioGRID Reconstituted Complex
SMAD4 BioGRID BTRC GeneID BioGRID Affinity Capture-Western; Two-hybrid
SMAD4 BioGRID EP300 GeneID BioGRID Affinity Capture-Western; Protein-peptide; Reconstituted Complex
SMAD4 BioGRID ZBTB7A GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SMAD4 BioGRID CHAF1B GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID JUN GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID NKX2-5 GeneID BioGRID Affinity Capture-MS; Affinity Capture-RNA
SMAD4 BioGRID CDKN1A GeneID BioGRID Co-localization
SMAD4 BioGRID NFKB1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID NFIX GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID XPO1 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID SERPINB5 GeneID BioGRID Two-hybrid
SMAD4 BioGRID LRATD2 GeneID BioGRID Two-hybrid
SMAD4 BioGRID S100A14 GeneID BioGRID Two-hybrid
SMAD4 BioGRID BEX1 GeneID BioGRID Two-hybrid
SMAD4 BioGRID BCAS3 GeneID BioGRID Two-hybrid
SMAD4 BioGRID DKK3 GeneID BioGRID Two-hybrid
SMAD4 BioGRID LYPD3 GeneID BioGRID Two-hybrid
SMAD4 BioGRID IL24 GeneID BioGRID Two-hybrid
SMAD4 BioGRID GREB1 GeneID BioGRID Two-hybrid
SMAD4 BioGRID THRSP GeneID BioGRID Two-hybrid
SMAD4 BioGRID PARD3 GeneID BioGRID Reconstituted Complex
SMAD4 BioGRID NFIA GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
SMAD4 BioGRID SHMT1 GeneID BioGRID Co-fractionation
SMAD4 BioGRID ALDOC GeneID BioGRID Co-fractionation
SMAD4 BioGRID SUMO1 GeneID BioGRID Affinity Capture-Western
SMAD4 BioGRID Dok1 GeneID BioGRID Affinity Capture-Western
SMAD4 BioGRID GLI1 GeneID BioGRID Affinity Capture-Western
SMAD4 BioGRID RASSF5 GeneID BioGRID Two-hybrid
SMAD4 BioGRID SMURF1 GeneID BioGRID Affinity Capture-Western
SMAD4 BioGRID CRYAB GeneID BioGRID Affinity Capture-Western
SMAD4 BioGRID NLK GeneID BioGRID Affinity Capture-MS; Two-hybrid
SMAD4 BioGRID OTUB1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
SMAD4 BioGRID FHL3 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
SMAD4 BioGRID FHL2 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
SMAD4 BioGRID FHL1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
SMAD4 BioGRID CSNK1D GeneID BioGRID Affinity Capture-Western
SMAD4 BioGRID TGFB1I1 GeneID BioGRID Affinity Capture-Western
SMAD4 BioGRID NCOR1 GeneID BioGRID Affinity Capture-Western
SMAD4 BioGRID KLF5 GeneID BioGRID Affinity Capture-Western
SMAD4 BioGRID IRF7 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
SMAD4 BioGRID IRF3 GeneID BioGRID Affinity Capture-Western
SMAD4 BioGRID ZNF521 GeneID BioGRID Affinity Capture-Western
SMAD4 BioGRID ZNF423 GeneID BioGRID Affinity Capture-Western
SMAD4 BioGRID SOX12 GeneID BioGRID Two-hybrid
SMAD4 BioGRID SNRNP70 GeneID BioGRID Two-hybrid
SMAD4 BioGRID RPL28 GeneID BioGRID Two-hybrid
SMAD4 BioGRID RFX1 GeneID BioGRID Two-hybrid
SMAD4 BioGRID RALA GeneID BioGRID Two-hybrid
SMAD4 BioGRID PSMD11 GeneID BioGRID Two-hybrid
SMAD4 BioGRID PSG9 GeneID BioGRID Two-hybrid
SMAD4 BioGRID PSG2 GeneID BioGRID Two-hybrid
SMAD4 BioGRID MAPK13 GeneID BioGRID Two-hybrid
SMAD4 BioGRID PLG GeneID BioGRID Two-hybrid
SMAD4 BioGRID SERPINA1 GeneID BioGRID Two-hybrid
SMAD4 BioGRID NOTCH4 GeneID BioGRID Affinity Capture-Western
SMAD4 BioGRID MYOD1 GeneID BioGRID Two-hybrid
SMAD4 BioGRID SMAD5 GeneID BioGRID Affinity Capture-Western; Two-hybrid
SMAD4 BioGRID JUNB GeneID BioGRID Reconstituted Complex; Two-hybrid
SMAD4 BioGRID DNAJB2 GeneID BioGRID Two-hybrid
SMAD4 BioGRID HDLBP GeneID BioGRID Two-hybrid
SMAD4 BioGRID GATA2 GeneID BioGRID Affinity Capture-Western; Two-hybrid
SMAD4 BioGRID FN1 GeneID BioGRID Two-hybrid
SMAD4 BioGRID FBLN1 GeneID BioGRID Two-hybrid
SMAD4 BioGRID CSH2 GeneID BioGRID Two-hybrid
SMAD4 BioGRID CSH1 GeneID BioGRID Two-hybrid
SMAD4 BioGRID CD59 GeneID BioGRID Two-hybrid
SMAD4 BioGRID DCP1B GeneID BioGRID Two-hybrid
SMAD4 BioGRID UHRF2 GeneID BioGRID Two-hybrid
SMAD4 BioGRID STK11IP GeneID BioGRID Affinity Capture-Western; Two-hybrid
SMAD4 BioGRID USB1 GeneID BioGRID Two-hybrid
SMAD4 BioGRID RMND5B GeneID BioGRID Two-hybrid
SMAD4 BioGRID PAPPA2 GeneID BioGRID Two-hybrid
SMAD4 BioGRID ZBED5 GeneID BioGRID Two-hybrid
SMAD4 BioGRID XPO5 GeneID BioGRID Two-hybrid
SMAD4 BioGRID ATF7IP GeneID BioGRID Two-hybrid
SMAD4 BioGRID TENM3 GeneID BioGRID Two-hybrid
SMAD4 BioGRID PRPF40A GeneID BioGRID Two-hybrid
SMAD4 BioGRID NELFCD GeneID BioGRID Two-hybrid
SMAD4 BioGRID CYFIP2 GeneID BioGRID Two-hybrid
SMAD4 BioGRID GPNMB GeneID BioGRID Two-hybrid
SMAD4 BioGRID CNKSR1 GeneID BioGRID Two-hybrid
SMAD4 BioGRID TM9SF2 GeneID BioGRID Two-hybrid
SMAD4 BioGRID PIAS1 GeneID BioGRID Two-hybrid
SMAD4 BioGRID NR0B2 GeneID BioGRID Two-hybrid
SMAD4 BioGRID ZMYM2 GeneID BioGRID Two-hybrid
SMAD4 BioGRID TDG GeneID BioGRID Two-hybrid
SMAD4 BioGRID TCTA GeneID BioGRID Two-hybrid
SMAD4 BioGRID SPTBN1 GeneID BioGRID Affinity Capture-Western
SMAD4 BioGRID EEF1A1 GeneID BioGRID Two-hybrid
SMAD4 BioGRID HERC5 GeneID BioGRID Affinity Capture-Western
SMAD4 BioGRID ZMIZ1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
SMAD4 BioGRID PIAS2 GeneID BioGRID Reconstituted Complex
SMAD4 BioGRID TGFBR1 GeneID BioGRID Affinity Capture-Luminescence; Co-fractionation
SMAD4 BioGRID SP1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SMAD4 BioGRID PAX6 GeneID BioGRID Affinity Capture-Western
SMAD4 BioGRID NCBP1 GeneID BioGRID Affinity Capture-RNA
SMAD4 BioGRID THOC2 GeneID BioGRID Affinity Capture-RNA
SMAD4 BioGRID ALYREF GeneID BioGRID Affinity Capture-RNA
SMAD4 BioGRID EIF4A3 GeneID BioGRID Affinity Capture-RNA
SMAD4 BioGRID THOC5 GeneID BioGRID Affinity Capture-RNA
SMAD4 BioGRID DDX39B GeneID BioGRID Affinity Capture-RNA
SMAD4 BioGRID RNF11 GeneID BioGRID Affinity Capture-Western
SMAD4 BioGRID WWP1 GeneID BioGRID Affinity Capture-Western
SMAD4 BioGRID ISG15 GeneID BioGRID Affinity Capture-MS
SMAD4 BioGRID DACH1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
SMAD4 BioGRID FOXO3 GeneID BioGRID Affinity Capture-Western
SMAD4 BioGRID HNF4A GeneID BioGRID Reconstituted Complex
SMAD4 BioGRID NUP214 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
SMAD4 BioGRID STUB1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
SMAD4 BioGRID KDM6B GeneID BioGRID Affinity Capture-Western
SMAD4 Protein OCLN GeneID HPRD
SMAD4 BioGRID PIAS4 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SMAD4 BioGRID MECOM GeneID BioGRID Reconstituted Complex
SMAD4 BioGRID DAXX GeneID BioGRID Affinity Capture-Western; Two-hybrid
SMAD4 BioGRID YY1 GeneID BioGRID Affinity Capture-Western; Co-localization; Reconstituted Complex
SMAD4 BioGRID SKP2 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
SMAD4 BioGRID NKX3-2 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
SMAD4 BioGRID SMAD6 GeneID BioGRID Affinity Capture-Western
SMAD4 Protein EIF2AK4 GeneID HPRD
SMAD4 Protein ZNF521 GeneID HPRD
SMAD4 Protein UHRF2 GeneID HPRD
SMAD4 Protein PBK GeneID HPRD
SMAD4 Protein ZBED5 GeneID HPRD
SMAD4 Protein EID2 GeneID HPRD
SMAD4 Protein FBXO34 GeneID HPRD
SMAD4 Protein RSPH14 GeneID HPRD
SMAD4 Protein HMG20A GeneID HPRD
SMAD4 Protein NELFCD GeneID HPRD
SMAD4 Protein DACH1 GeneID HPRD
SMAD4 Protein PIAS1 GeneID HPRD
SMAD4 Protein TCTA GeneID HPRD
SMAD4 Protein MEX3B GeneID HPRD
SMAD4 Protein RHEBL1 GeneID HPRD
SMAD4 Protein RASL12 GeneID HPRD
SMAD4 Protein RASD2 GeneID HPRD
SMAD4 Protein TENM3 GeneID HPRD
SMAD4 Protein DCP1B GeneID HPRD
SMAD4 Protein ARL5B GeneID HPRD
SMAD4 Protein ECSIT GeneID HPRD
SMAD4 Protein NUAK2 GeneID HPRD
SMAD4 Protein CNKSR1 GeneID HPRD
SMAD4 Protein STK35 GeneID HPRD
SMAD4 Protein PRPF40A GeneID HPRD
SMAD4 Protein FBXO30 GeneID HPRD
SMAD4 Protein PLK4 GeneID HPRD
SMAD4 Protein PAPPA2 GeneID HPRD
SMAD4 Protein ATF7IP GeneID HPRD
SMAD4 Protein TSSK3 GeneID HPRD
SMAD4 Protein RHOJ GeneID HPRD
SMAD4 Protein TOB1 GeneID HPRD
SMAD4 Protein TM9SF2 GeneID HPRD
SMAD4 Protein MAPK13 GeneID HPRD
SMAD4 Protein PIAS3 GeneID HPRD
SMAD4 Protein UBE2I GeneID HPRD
SMAD4 Protein DLX1 GeneID HPRD
SMAD4 Protein UBA52 GeneID HPRD
SMAD4 Protein PSG9 GeneID HPRD
SMAD4 Protein PSG2 GeneID HPRD
SMAD4 Protein UBE2Z GeneID HPRD
SMAD4 Protein NAT8 GeneID HPRD
SMAD4 Protein CSH1 GeneID HPRD
SMAD4 Protein RMND5B GeneID HPRD
SMAD4 Protein USB1 GeneID HPRD
SMAD4 Protein DNAJB2 GeneID HPRD
SMAD4 Protein SNIP1 GeneID HPRD
SMAD4 Protein TGFBRAP1 GeneID HPRD
SMAD4 Protein PIAS2 GeneID HPRD
SMAD4 Protein PIAS4 GeneID HPRD
SMAD4 Protein COPS5 GeneID HPRD
SMAD4 Protein UBB GeneID HPRD
SMAD4 Protein RAB34 GeneID HPRD
SMAD4 Protein RAB25 GeneID HPRD
SMAD4 Protein XPO5 GeneID HPRD
SMAD4 Protein RAB2B GeneID HPRD
SMAD4 Protein STUB1 GeneID HPRD
SMAD4 Protein STK11IP GeneID HPRD
SMAD4 Protein DCP1A GeneID HPRD
SMAD4 Protein ERBIN GeneID HPRD
SMAD4 Protein PARD3 GeneID HPRD
SMAD4 Protein RAB38 GeneID HPRD
SMAD4 Protein TRAP1 GeneID HPRD
SMAD4 Protein RHOD GeneID HPRD
SMAD4 Protein FSTL3 GeneID HPRD
SMAD4 Protein NEK6 GeneID HPRD
SMAD4 Protein ARFRP1 GeneID HPRD
SMAD4 Protein ZNF423 GeneID HPRD
SMAD4 Protein PSMD11 GeneID HPRD
SMAD4 Protein GPNMB GeneID HPRD
SMAD4 Protein CTCF GeneID HPRD
SMAD4 Protein UBE2L3 GeneID HPRD
SMAD4 Protein RPL28 GeneID HPRD
SMAD4 Protein FOXH1 GeneID HPRD
SMAD4 Protein BTRC GeneID HPRD
SMAD4 Protein RIPK2 GeneID HPRD
SMAD4 Protein SMAD9 GeneID HPRD
SMAD4 Protein SMAD5 GeneID HPRD
SMAD4 Protein SMAD3 GeneID HPRD
SMAD4 Protein CHEK1 GeneID HPRD
SMAD4 Protein APBB2 GeneID HPRD
SMAD4 Protein EP300 GeneID HPRD
SMAD4 Protein FOXO3 GeneID HPRD
SMAD4 Protein RAB13 GeneID HPRD
SMAD4 Protein PAK1 GeneID HPRD
SMAD4 Protein ZMYM2 GeneID HPRD
SMAD4 Protein CAMK2G GeneID HPRD
SMAD4 Protein RAC2 GeneID HPRD
SMAD4 Protein ESR2 GeneID HPRD
SMAD4 Protein SMAD1 GeneID HPRD
SMAD4 Protein SQSTM1 GeneID HPRD
SMAD4 Protein TDG GeneID HPRD
SMAD4 Protein SMAD2 GeneID HPRD
SMAD4 Protein DVL1 GeneID HPRD
SMAD4 Protein ACVR1B GeneID HPRD
SMAD4 Protein AP2B1 GeneID HPRD
SMAD4 Protein SMAD4 GeneID HPRD
SMAD4 Protein MEF2A GeneID HPRD
SMAD4 Protein HNF4A GeneID HPRD
SMAD4 Protein CREBBP GeneID HPRD
SMAD4 Protein RRAS2 GeneID HPRD
SMAD4 Protein RFX1 GeneID HPRD
SMAD4 Protein TFE3 GeneID HPRD
SMAD4 Protein AR GeneID HPRD
SMAD4 Protein SASH3 GeneID HPRD
SMAD4 Protein CITED1 GeneID HPRD
SMAD4 Protein HDGF GeneID HPRD
SMAD4 Protein FOXO4 GeneID HPRD
SMAD4 Protein ZNF8 GeneID HPRD
SMAD4 Protein RPS27A GeneID HPRD
SMAD4 Protein TGFBR2 GeneID HPRD
SMAD4 Protein TGFBR1 GeneID HPRD
SMAD4 Protein CEBPB GeneID HPRD
SMAD4 Protein SP1 GeneID HPRD
SMAD4 Protein ITK GeneID HPRD
SMAD4 Protein SPTBN1 GeneID HPRD
SMAD4 Protein SNRNP70 GeneID HPRD
SMAD4 Protein RALA GeneID HPRD
SMAD4 Protein RAB3B GeneID HPRD
SMAD4 Protein RHOG GeneID HPRD
SMAD4 Protein MAPK1 GeneID HPRD
SMAD4 Protein PRKAR1B GeneID HPRD
SMAD4 Protein PRKAR2A GeneID HPRD
SMAD4 Protein SKIL GeneID HPRD
SMAD4 Protein GLI3 GeneID HPRD
SMAD4 Protein JUND GeneID HPRD
SMAD4 Protein JUNB GeneID HPRD
SMAD4 Protein JUN GeneID HPRD
SMAD4 Protein NOTCH4 GeneID HPRD
SMAD4 Protein FOXG1 GeneID HPRD
SMAD4 Protein NRAS GeneID HPRD
SMAD4 Protein SKI GeneID HPRD
SMAD4 Protein AKT1 GeneID HPRD
SMAD4 Protein MYOD1 GeneID HPRD
SMAD4 Protein MAX GeneID HPRD
SMAD4 Protein LEF1 GeneID HPRD
SMAD4 Protein HOXC8 GeneID HPRD
SMAD4 Protein HOXA9 GeneID HPRD
SMAD4 Protein HDLBP GeneID HPRD
SMAD4 Protein FOXO1 GeneID HPRD
SMAD4 Protein FBLN1 GeneID HPRD
SMAD4 Protein FN1 GeneID HPRD
SMAD4 Protein EWSR1 GeneID HPRD
SMAD4 Protein ESR1 GeneID HPRD
SMAD4 Protein EEF1A1 GeneID HPRD
SMAD4 Protein ATF2 GeneID HPRD
SMAD4 Protein RBL1 GeneID HPRD
SMAD4 Protein CTNNB1 GeneID HPRD
SMAD4 Protein NUP214 GeneID HPRD
SMAD4 Protein BRCA1 GeneID HPRD
SMAD4 Protein CD59 GeneID HPRD
SMAD4 BioGRID LEF1 GeneID BioGRID Reconstituted Complex
SMAD4 BioGRID CITED1 GeneID BioGRID Two-hybrid
SMAD4 BioGRID HOXA9 GeneID BioGRID Affinity Capture-Western
SMAD4 BioGRID Zfp128 GeneID BioGRID Reconstituted Complex
SMAD4 BioGRID SNW1 GeneID BioGRID Phenotypic Enhancement; Two-hybrid
SMAD4 BioGRID TGFBRAP1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
SMAD4 BioGRID CEBPD GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
SMAD4 BioGRID CEBPB GeneID BioGRID Reconstituted Complex
SMAD4 BioGRID CEBPA GeneID BioGRID Reconstituted Complex
SMAD4 BioGRID HOXC8 GeneID BioGRID Affinity Capture-Western
SMAD4 BioGRID DLX1 GeneID BioGRID Affinity Capture-Western
SMAD4 BioGRID CTNNB1 GeneID BioGRID Affinity Capture-Western
SMAD4 BioGRID CAMK2G GeneID BioGRID Biochemical Activity
SMAD4 BioGRID AR GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
SMAD4 BioGRID PIAS3 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
SMAD4 BioGRID TOB1 GeneID BioGRID Affinity Capture-Western
SMAD4 BioGRID FOXH1 GeneID BioGRID Reconstituted Complex; Two-hybrid
SMAD4 BioGRID TFE3 GeneID BioGRID Reconstituted Complex
SMAD4 BioGRID RBL1 GeneID BioGRID Affinity Capture-Western
SMAD4 BioGRID MAX GeneID BioGRID Reconstituted Complex
SMAD4 BioGRID ATF2 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SMAD4 BioGRID KPNB1 GeneID BioGRID Affinity Capture-Western
SMAD4 BioGRID MDM4 GeneID BioGRID Reconstituted Complex
SMAD4 BioGRID ERBIN GeneID BioGRID Reconstituted Complex
SMAD4 BioGRID DVL1 GeneID BioGRID Reconstituted Complex
SMAD4 BioGRID EID2 GeneID BioGRID Affinity Capture-Western
SMAD4 BioGRID FOXO4 GeneID BioGRID Affinity Capture-Western
SMAD4 BioGRID FOXO1 GeneID BioGRID Affinity Capture-Western
SMAD4 BioGRID EWSR1 GeneID BioGRID Two-hybrid
SMAD4 BioGRID Arhgef11 GeneID BioGRID Affinity Capture-Luminescence
SMAD4 BioGRID Ripk2 GeneID BioGRID Affinity Capture-Luminescence
SMAD4 BioGRID Rhoj GeneID BioGRID Affinity Capture-Luminescence
SMAD4 BioGRID Rps27a GeneID BioGRID Affinity Capture-Luminescence
SMAD4 BioGRID Arfrp1 GeneID BioGRID Affinity Capture-Luminescence
SMAD4 BioGRID Rab2b GeneID BioGRID Affinity Capture-Luminescence
SMAD4 BioGRID Arl5b GeneID BioGRID Affinity Capture-Luminescence
SMAD4 BioGRID Rasd2 GeneID BioGRID Affinity Capture-Luminescence
SMAD4 BioGRID Nuak2 GeneID BioGRID Affinity Capture-Luminescence
SMAD4 BioGRID Rab38 GeneID BioGRID Affinity Capture-Luminescence
SMAD4 BioGRID Ap2b1 GeneID BioGRID Affinity Capture-Luminescence
SMAD4 BioGRID Rsph14 GeneID BioGRID Affinity Capture-Luminescence
SMAD4 BioGRID Rab3b GeneID BioGRID Affinity Capture-Luminescence
SMAD4 BioGRID Rab13 GeneID BioGRID Affinity Capture-Luminescence
SMAD4 BioGRID Ilkap GeneID BioGRID Affinity Capture-Luminescence
SMAD4 BioGRID Stk35 GeneID BioGRID Affinity Capture-Luminescence
SMAD4 BioGRID Rras2 GeneID BioGRID Affinity Capture-Luminescence
SMAD4 BioGRID Trim35 GeneID BioGRID Affinity Capture-Luminescence
SMAD4 BioGRID Nek6 GeneID BioGRID Affinity Capture-Luminescence
SMAD4 BioGRID Tssk3 GeneID BioGRID Affinity Capture-Luminescence
SMAD4 BioGRID Rnf14 GeneID BioGRID Affinity Capture-Luminescence
SMAD4 BioGRID Rnf138 GeneID BioGRID Affinity Capture-Luminescence
SMAD4 BioGRID Rhog GeneID BioGRID Affinity Capture-Luminescence
SMAD4 BioGRID Arhgef7 GeneID BioGRID Affinity Capture-Luminescence
SMAD4 BioGRID Pbk GeneID BioGRID Affinity Capture-Luminescence
SMAD4 BioGRID Eif2ak4 GeneID BioGRID Affinity Capture-Luminescence
SMAD4 BioGRID Map2k3 GeneID BioGRID Affinity Capture-Luminescence
SMAD4 BioGRID Ubb GeneID BioGRID Affinity Capture-Luminescence
SMAD4 BioGRID Plk4 GeneID BioGRID Affinity Capture-Luminescence
SMAD4 BioGRID Stat1 GeneID BioGRID Affinity Capture-Luminescence
SMAD4 BioGRID Rab34 GeneID BioGRID Affinity Capture-Luminescence
SMAD4 BioGRID Rac2 GeneID BioGRID Affinity Capture-Luminescence
SMAD4 BioGRID Sqstm1 GeneID BioGRID Affinity Capture-Luminescence
SMAD4 BioGRID Ocln GeneID BioGRID Affinity Capture-Luminescence
SMAD4 BioGRID Nras GeneID BioGRID Affinity Capture-Luminescence
SMAD4 BioGRID Smad3 GeneID BioGRID Affinity Capture-Luminescence
SMAD4 BioGRID Smad2 GeneID BioGRID Affinity Capture-Luminescence
SMAD4 BioGRID Smad1 GeneID BioGRID Affinity Capture-Luminescence
SMAD4 BioGRID Uhmk1 GeneID BioGRID Affinity Capture-Luminescence
SMAD4 BioGRID Itk GeneID BioGRID Affinity Capture-Luminescence
SMAD4 BioGRID Hdgf GeneID BioGRID Affinity Capture-Luminescence
SMAD4 BioGRID Chek1 GeneID BioGRID Affinity Capture-Luminescence
SMAD4 BioGRID Rhod GeneID BioGRID Affinity Capture-Luminescence
SMAD4 BioGRID Apbb2 GeneID BioGRID Affinity Capture-Luminescence
SMAD4 Protein STUB1 GeneID BIND Smad4 interacts with CHIP. This interaction was modeled on a demonstrated interaction between Smad1 and CHIP, both from an unspecified species.
SMAD4 Protein TGFB1I1 GeneID BIND ARA55 interacts with Smad4. This interaction was modeled on a demonstrated interaction between human ARA55 and Smad4 from an unspecified species.
SMAD4 Protein TGFBR1 GeneID BIND T-beta-RI phosphorylates hMAD-4. This interaction was modeled on a demonstrated interaction between T-beta-RI from an unspecified species and human hMAD-4.
SMAD4 Protein TGFBR2 GeneID BIND T-beta-RII phosphorylates hMAD-4. This interaction was modeled on a demonstrated interaction between T-beta-RII from an unspecified species and human hMAD-4.
SMAD4 Protein SMAD2 GeneID BIND Smad2 interacts with Smad4. This interaction was modeled on a demonstrated interaction between Smad2 from an unspecified species and Smad4 from an unspecified species.
SMAD4 Protein SMAD3 GeneID BIND Smad3 interacts with Smad4. This interaction was modeled on a demonstrated interaction between Smad3 from an unspecified species and Smad4 from an unspecified species.
SMAD4 Protein CEBPB GeneID BIND CEBPB (C/EBP-beta) interacts with SMAD4. This interaction was modeled on a demonstrated interaction between CEBPB and SMAD4, both from unspecified species.
SMAD4 Protein SKI GeneID BIND c-Ski interacts with Smad4. This interaction was modelled on a demonstrated interaction between Smad4 from an unspecified source and human c-Ski.
SMAD4 Protein SMAD2 GeneID BIND Smad4 interacts with Smad2.
SMAD4 Protein SKI GeneID BIND Smad4 interacts with Ski. This interaction was modeled on a demonstrated interaction between human Smad4 and Ski from an unspecified species.
SMAD4 Protein SMAD1 GeneID BIND Smad4 interacts with Smad1.
SMAD4 Protein SMAD3 GeneID BIND Smad4 interacts with Smad3.
SMAD4 Protein SKIL GeneID BIND Smad4 interacts with SnoN. This interaction was modeled on a demonstrated interaction between human Smad4 and SnoN from an unspecified species.
SMAD4 Protein SUMO1 GeneID BIND SMAD4 is sumoylated.
SMAD4 None None None BIND p300 interacts with Smad4 fragment. p300 interacting with full-length Smad4 could not be demonstrated in vitro. This interaction was modeled on a demonstrated interaction between p300 from an unspecified species and human Smad4 fragment.
SMAD4 Protein BRCA1 GeneID BIND BRCA1 interacts with Smad4. This interaction was modeled on a demonstrated interaction between BRCA1 from human and Smad4 from an unspecified species.
SMAD4 Protein TRIM33 GeneID BIND Smad4 interacts with Ecto.
SMAD4 Protein TSSK3 GeneID BIND SMAD4 interacts with STK22C. This interaction was modeled on a demonstrated interaction between human SMAD4 and mouse STK22C.
SMAD4 Protein CDKN1A GeneID BIND Smad4 binds the distal region of the p21Cip1 promoter.
SMAD4 Protein FOXO3 GeneID BIND FoxO3 interacts with Smad4.
SMAD4 Protein FOXO1 GeneID BIND FoxO1 interacts with Smad4.
SMAD4 Protein FOXO4 GeneID BIND FoxO4 interacts with Smad4.
StringDB
A B experiments database textmining combined score hadb nhadb
SMAD4 MYOD1 66 900 390 948 1 1
SMAD4 POU6F1 0 0 46 213 1 1
SMAD4 PMEPA1 0 0 325 335 1 1
SMAD4 HOXD9 0 0 57 193 1 1
SMAD4 COL10A1 0 0 231 230 1 1
SMAD4 TNFAIP1 0 0 150 368 1 1
SMAD4 MAPK7 0 0 247 291 1 1
SMAD4 IRF4 0 0 160 159 1 1
SMAD4 NFIA 270 0 150 381 1 1
SMAD4 VEGFA 0 0 566 566 1 2
SMAD4 SNIP1 270 900 549 964 1 1
SMAD4 ARID2 0 0 391 423 1 1
SMAD4 HECW2 0 0 0 174 1 1
SMAD4 CYFIP2 130 0 45 152 1 1
SMAD4 PTEN 0 0 710 859 1 2
SMAD4 ATOH8 0 0 141 161 1 1
SMAD4 ID3 0 0 369 385 1 1
SMAD4 LMNB2 0 0 113 154 1 1
SMAD4 TIMP3 0 0 325 325 1 1
SMAD4 ENSG00000258947 0 0 156 170 1 1
SMAD4 MEOX2 0 0 188 239 1 1
SMAD4 MAPK14 0 0 393 508 1 2
SMAD4 CFL1 0 0 212 230 1 1
SMAD4 MGEA5 0 0 81 166 1 1
SMAD4 SREBF1 0 0 171 299 1 1
SMAD4 UBA52 129 600 0 636 1 1
SMAD4 HIST1H4A 0 0 170 169 1 1
SMAD4 MAPK10 0 800 670 933 1 2
SMAD4 KERA 0 0 81 158 1 1
SMAD4 WT1 0 0 323 340 1 1
SMAD4 FHL1 270 0 276 453 1 1
SMAD4 CLIC4 0 0 453 453 1 1
SMAD4 BMP4 0 0 808 964 1 1
SMAD4 TCF4 0 0 230 274 1 1
SMAD4 SYK 0 0 150 225 1 2
SMAD4 LEP 0 0 207 207 1 1
SMAD4 HFE 0 0 584 587 1 1
SMAD4 SAMD7 0 0 167 167 1 1
SMAD4 NFKBIA 0 0 367 377 1 2
SMAD4 PRKG2 0 0 0 200 1 1
SMAD4 ONECUT2 0 0 145 163 1 1
SMAD4 MSH3 0 0 408 410 1 1
SMAD4 PLEKHA7 0 0 0 174 1 1
SMAD4 RET 0 0 518 548 1 1
SMAD4 ENSG00000267261 0 0 0 193 1 1
SMAD4 BAZ2B 0 0 0 168 1 1
SMAD4 LHCGR 0 0 134 199 1 1
SMAD4 TRIM63 0 900 150 914 1 1
SMAD4 IDH2 0 0 460 459 1 1
SMAD4 BAMBI 0 0 500 508 1 1
SMAD4 AXIN1 0 0 499 568 1 1
SMAD4 JMJD1C 0 0 60 183 1 1
SMAD4 MRE11A 0 0 263 283 1 1
SMAD4 SMAD5 633 900 988 987 1 1
SMAD4 EZR 0 0 136 171 1 1
SMAD4 SFRP1 0 0 370 381 1 1
SMAD4 ATM 0 0 601 639 1 2
SMAD4 SHC1 128 0 324 385 1 1
SMAD4 MTDH 0 0 142 196 1 2
SMAD4 EFNB2 0 0 182 181 1 1
SMAD4 GFAP 0 0 194 194 1 2
SMAD4 NCK1 0 0 70 186 1 1
SMAD4 CHD4 0 0 127 164 1 1
SMAD4 RBPJ 0 0 611 640 1 1
SMAD4 COL1A1 0 0 469 578 1 2
SMAD4 ITGB4 0 0 151 169 1 1
SMAD4 CDH11 0 0 217 230 1 1
SMAD4 ATG7 0 0 162 178 1 2
SMAD4 TGFBR2 213 900 871 991 1 1
SMAD4 TJP1 0 0 391 408 1 1
SMAD4 TRAT1 0 0 206 206 1 1
SMAD4 HIVEP2 0 0 376 397 1 1
SMAD4 ACTG1 0 0 224 266 1 1
SMAD4 RPL38 0 0 44 208 1 1
SMAD4 IKZF1 0 0 134 217 1 1
SMAD4 ITGB5 0 0 112 185 1 1
SMAD4 BTG2 0 0 142 264 1 1
SMAD4 PIAS3 270 900 217 938 1 1
SMAD4 ADAM17 0 0 241 258 1 1
SMAD4 ARID1A 0 0 652 666 1 1
SMAD4 TMEFF1 0 0 218 247 1 1
SMAD4 SOCS6 0 0 160 172 1 1
SMAD4 TGFBR1 540 900 988 999 1 1
SMAD4 SMEK2 0 0 0 167 1 1
SMAD4 S100A4 0 0 394 394 1 1
SMAD4 HSPB2 0 0 150 151 1 1
SMAD4 LAMC3 0 0 94 174 1 1
SMAD4 GLI1 270 0 707 782 1 2
SMAD4 ADAM19 0 0 136 190 1 1
SMAD4 HSPB1 0 0 158 159 1 2
SMAD4 RARA 0 0 206 229 1 2
SMAD4 IKBKG 0 0 218 218 1 1
SMAD4 VTN 0 0 202 215 1 1
SMAD4 KDM5B 0 0 154 154 1 1
SMAD4 PARD6B 0 0 57 156 1 1
SMAD4 RALA 72 0 142 205 1 1
SMAD4 PCBP1 0 0 193 193 1 1
SMAD4 AKT3 0 0 282 513 1 2
SMAD4 TFF2 0 0 166 173 1 1
SMAD4 RCOR1 0 0 131 151 1 1
SMAD4 STMN1 0 0 142 163 1 1
SMAD4 RPS6KA1 0 0 189 189 1 1
SMAD4 SKIL 974 900 954 999 1 1
SMAD4 HNRNPK 0 0 112 153 1 1
SMAD4 LATS1 0 0 243 265 1 1
SMAD4 NCAM1 0 0 175 175 1 1
SMAD4 NBN 0 0 95 152 1 1
SMAD4 DACH1 270 0 951 969 1 1
SMAD4 TBX21 0 0 251 278 1 1
SMAD4 EYA4 0 0 95 331 1 1
SMAD4 RNH1 0 0 181 181 1 1
SMAD4 SMARCD2 0 0 0 180 1 1
SMAD4 T 0 0 92 261 1 1
SMAD4 GNA11 0 0 469 497 1 1
SMAD4 GATA2 131 0 684 765 1 1
SMAD4 ITGAM 0 0 241 240 1 1
SMAD4 DIO3 0 0 123 150 1 1
SMAD4 DCP1B 72 0 431 461 1 1
SMAD4 ZNF510 129 0 0 151 1 1
SMAD4 MAP3K5 0 0 261 261 1 1
SMAD4 ANKMY2 0 0 0 157 1 1
SMAD4 KCP 0 0 204 302 1 1
SMAD4 RAC1 0 0 144 163 1 2
SMAD4 RBBP4 0 900 96 909 1 1
SMAD4 COPS5 761 0 498 882 1 1
SMAD4 LYN 0 0 113 174 1 1
SMAD4 CTSK 0 0 166 165 1 2
SMAD4 NOX1 0 0 166 165 1 1
SMAD4 SPI1 0 0 233 275 1 1
SMAD4 MAPK8IP3 0 0 325 325 1 1
SMAD4 CTSB 0 0 156 155 1 2
SMAD4 PJA2 0 0 0 174 1 1
SMAD4 MCL1 0 0 325 339 1 2
SMAD4 RBM10 0 0 244 280 1 1
SMAD4 SMARCA4 0 0 405 405 1 1
SMAD4 SIRT1 0 0 391 507 1 2
SMAD4 DLK1 0 0 181 198 1 1
SMAD4 HECTD3 0 0 0 174 1 1
SMAD4 XBP1 0 0 136 156 1 2
SMAD4 STAT2 0 0 122 194 1 1
SMAD4 SOX6 0 0 161 186 1 1
SMAD4 NUP160 0 0 52 161 1 1
SMAD4 HIPK2 0 0 418 432 1 2
SMAD4 SP3 0 900 233 928 1 1
SMAD4 TP63 209 0 242 388 1 2
SMAD4 GATA6 0 0 526 602 1 1
SMAD4 SAMD3 0 0 325 367 1 1
SMAD4 TRAPPC6A 0 0 81 186 1 1
SMAD4 RAD51D 0 0 377 390 1 1
SMAD4 MANF 0 0 305 305 1 1
SMAD4 MYO10 0 0 77 207 1 1
SMAD4 PUM1 0 0 81 266 1 1
SMAD4 UFM1 0 0 60 187 1 1
SMAD4 YIPF1 0 0 124 151 1 1
SMAD4 PPP5D1 0 0 0 173 1 1
SMAD4 CAMK2G 270 0 48 282 1 1
SMAD4 WNT3A 0 0 456 550 1 2
SMAD4 NIPAL4 0 0 0 162 1 1
SMAD4 ATG5 0 0 181 198 1 2
SMAD4 KSR1 0 0 146 204 1 1
SMAD4 MAP2K6 0 0 182 205 1 1
SMAD4 TOR1AIP1 0 0 0 151 1 1
SMAD4 ITGB3 0 0 211 245 1 1
SMAD4 FBXO34 128 0 0 160 1 1
SMAD4 TIA1 0 0 54 173 1 1
SMAD4 SLC40A1 0 0 219 219 1 1
SMAD4 BGN 0 0 290 302 1 1
SMAD4 SEMA5A 0 0 143 201 1 1
SMAD4 GNAI3 0 0 0 190 1 2
SMAD4 SNRK 0 0 0 174 1 1
SMAD4 TFG 0 0 323 338 1 1
SMAD4 ENSG00000267618 0 0 378 391 1 1
SMAD4 FZD5 0 0 143 212 1 1
SMAD4 NR6A1 0 0 124 181 1 1
SMAD4 WEE1 241 0 228 402 1 1
SMAD4 DERL1 0 0 139 182 1 1
SMAD4 SUFU 0 0 210 228 1 1
SMAD4 ADCY10 0 0 139 175 1 1
SMAD4 SFRP2 160 0 233 340 1 1
SMAD4 ARF6 0 0 536 559 1 1
SMAD4 SNAPIN 0 0 60 234 1 1
SMAD4 ALDH1A1 0 0 282 282 1 1
SMAD4 ZMYND11 0 0 61 182 1 1
SMAD4 PMAIP1 0 0 202 202 1 2
SMAD4 CDKN2B 270 900 519 963 1 1
SMAD4 TLR2 0 0 156 189 1 2
SMAD4 PIK3CB 0 0 156 242 1 1
SMAD4 SKA1 0 0 113 266 1 1
SMAD4 LRRK2 0 0 82 189 1 2
SMAD4 MET 0 0 416 456 1 2
SMAD4 ERF 0 0 134 190 1 1
SMAD4 FGF20 0 0 49 213 1 1
SMAD4 NRAS 94 0 302 433 1 1
SMAD4 CHMP5 0 0 0 156 1 1
SMAD4 HSPA5 0 0 150 168 1 2
SMAD4 FOXP2 0 0 85 226 1 1
SMAD4 TFE3 486 900 203 955 1 2
SMAD4 E2F1 0 0 218 237 1 2
SMAD4 BTRC 874 0 715 965 1 1
SMAD4 TIAF1 312 0 583 712 1 1
SMAD4 SMYD2 0 0 427 427 1 1
SMAD4 EIF4A2 0 0 113 297 1 1
SMAD4 EPAS1 0 650 123 705 1 2
SMAD4 TGFB1I1 270 0 208 406 1 1
SMAD4 FOXO1 270 900 552 967 1 2
SMAD4 SOD2 0 0 159 164 1 2
SMAD4 DRAP1 0 900 305 927 1 1
SMAD4 CDK9 128 900 486 954 1 1
SMAD4 GDF6 0 0 234 332 1 1
SMAD4 FOS 0 900 578 957 1 2
SMAD4 S100A8 0 0 517 553 1 2
SMAD4 HEY2 0 0 204 228 1 1
SMAD4 YWHAZ 0 0 181 198 1 1
SMAD4 TWIST1 0 0 693 693 1 1
SMAD4 U2AFBP 0 0 170 169 1 1
SMAD4 PTK6 0 0 113 174 1 2
SMAD4 RBM39 0 0 47 153 1 1
SMAD4 ANGPTL4 0 0 202 218 1 1
SMAD4 INHBB 0 650 284 785 1 1
SMAD4 CRKL 0 0 174 223 1 1
SMAD4 PDX1 0 0 141 216 1 1
SMAD4 MSTN 0 900 519 976 1 1
SMAD4 PTPN11 0 0 451 525 1 1
SMAD4 IRAK3 0 0 109 170 1 1
SMAD4 MT-CO2 0 0 826 826 1 1
SMAD4 MEF2A 213 0 193 378 1 1
SMAD4 CRYAB 270 0 53 324 1 2
SMAD4 CSF1 0 0 218 218 1 1
SMAD4 HDAC1 486 900 905 995 1 2
SMAD4 PRDM1 0 0 181 216 1 1
SMAD4 SFN 0 0 190 190 1 2
SMAD4 EPHA3 0 0 155 213 1 1
SMAD4 FABP4 0 0 147 166 1 1
SMAD4 SST 0 0 174 175 1 1
SMAD4 BMPR1B 0 650 816 956 1 1
SMAD4 ERCC1 0 0 203 203 1 1
SMAD4 MGP 0 0 204 204 1 1
SMAD4 PBRM1 0 0 371 476 1 1
SMAD4 XRCC5 0 0 57 219 1 1
SMAD4 CCDC11 0 0 155 207 1 1
SMAD4 WNT2 0 0 286 607 1 1
SMAD4 RBL2 0 0 140 210 1 1
SMAD4 KLF2 0 0 234 253 1 1
SMAD4 CUL3 0 0 160 178 1 2
SMAD4 CHUK 0 0 262 368 1 1
SMAD4 HIST2H4A 0 0 170 169 1 1
SMAD4 BCAR1 0 0 160 159 1 1
SMAD4 FGF22 0 0 45 219 1 1
SMAD4 USP11 0 0 143 208 1 2
SMAD4 NOTCH2 0 0 359 441 1 1
SMAD4 PRMT2 0 0 54 186 1 1
SMAD4 DLX3 0 0 230 242 1 1
SMAD4 BHLHA15 0 0 224 229 1 1
SMAD4 CD28 0 0 180 179 1 1
SMAD4 GDF11 0 0 394 710 1 1
SMAD4 OSR2 0 0 155 177 1 1
SMAD4 CXCL5 0 0 208 208 1 1
SMAD4 ENSG00000160201 0 0 170 169 1 1
SMAD4 CXCL1 0 0 210 210 1 2
SMAD4 MMP14 0 0 320 357 1 1
SMAD4 LIMK1 0 0 256 323 1 1
SMAD4 DAXX 270 0 808 879 1 1
SMAD4 MYO5B 0 0 113 180 1 1
SMAD4 WFIKKN2 0 0 106 152 1 1
SMAD4 AFP 0 0 274 323 1 2
SMAD4 CDC27 0 0 150 193 1 1
SMAD4 FGF19 0 0 161 284 1 1
SMAD4 EEF1A1 130 0 118 225 1 1
SMAD4 PRMT5 282 0 107 334 1 1
SMAD4 CLDN4 0 0 194 194 1 1
SMAD4 SKP1 0 0 218 218 1 2
SMAD4 KDR 0 0 469 480 1 2
SMAD4 CLDN7 0 0 173 173 1 1
SMAD4 MPRIP 0 0 138 197 1 1
SMAD4 RAC2 128 0 193 295 1 1
SMAD4 RAB11A 0 0 96 167 1 2
SMAD4 YY1 270 0 397 575 1 1
SMAD4 DDX39B 435 0 0 447 1 1
SMAD4 NKX3-1 0 0 262 308 1 1
SMAD4 AGTR2 0 0 166 179 1 1
SMAD4 TBK1 0 0 90 229 1 2
SMAD4 HIST1H4D 0 0 170 169 1 1
SMAD4 TLX3 0 0 0 219 1 1
SMAD4 PEG3 0 0 204 224 1 2
SMAD4 FOXP3 0 0 369 461 1 2
SMAD4 YTHDC2 0 0 0 164 1 1
SMAD4 HYAL1 0 0 90 182 1 1
SMAD4 USP7 270 0 450 590 1 1
SMAD4 IRX6 0 0 107 228 1 1
SMAD4 PRKCD 0 0 215 215 1 2
SMAD4 MMP10 0 0 193 261 1 1
SMAD4 STAT5B 0 0 270 312 1 1
SMAD4 PIK3C2A 0 0 134 178 1 1
SMAD4 KRT19 0 0 406 413 1 1
SMAD4 RASSF5 426 0 57 435 1 1
SMAD4 TGFB1 0 900 595 985 1 2
SMAD4 DDX20 0 0 103 205 1 1
SMAD4 KLF8 0 0 146 168 1 1
SMAD4 TIAM1 0 0 181 181 1 1
SMAD4 CDC42 0 0 392 432 1 2
SMAD4 SIN3B 0 900 51 916 1 1
SMAD4 LRP8 0 0 432 439 1 1
SMAD4 TRIM58 0 0 113 178 1 1
SMAD4 DKK1 0 0 402 406 1 1
SMAD4 ZRANB2 0 0 53 153 1 1
SMAD4 APOE 0 0 164 163 1 2
SMAD4 CBFB 0 900 43 904 1 1
SMAD4 GATA5 0 0 220 344 1 1
SMAD4 FOXO3 486 900 801 995 1 2
SMAD4 ITGA6 0 0 164 170 1 1
SMAD4 KRT85 0 0 0 290 1 1
SMAD4 BGLAP 0 0 459 470 1 1
SMAD4 ACTG2 0 0 65 156 1 1
SMAD4 TNFSF11 0 0 325 325 1 2
SMAD4 BMPER 0 0 325 408 1 1
SMAD4 EWSR1 270 0 144 353 1 1
SMAD4 THOC5 435 0 0 435 1 1
SMAD4 TP53INP1 0 0 207 235 1 2
SMAD4 HNF4A 270 900 950 996 1 1
SMAD4 TAF2 0 0 0 182 1 1
SMAD4 ALYREF 435 0 0 442 1 1
SMAD4 NAGLU 0 0 0 206 1 1
SMAD4 EID2 270 0 324 485 1 1
SMAD4 TRIM28 0 0 123 150 1 2
SMAD4 CDKN3 0 0 375 386 1 1
SMAD4 EIF4EBP1 0 0 253 252 1 2
SMAD4 CYLD 0 0 255 399 1 1
SMAD4 KRT18 0 0 249 248 1 1
SMAD4 PMS2 0 0 596 605 1 1
SMAD4 TYMS 0 0 235 235 1 1
SMAD4 MACROD2 0 0 207 207 1 1
SMAD4 CRB1 0 0 0 163 1 1
SMAD4 FOXO4 270 900 218 943 1 1
SMAD4 AXL 0 0 235 287 1 2
SMAD4 PEX6 0 0 74 210 1 1
SMAD4 EYA2 0 0 120 235 1 1
SMAD4 HSP90AB1 0 0 68 317 1 2
SMAD4 FOXH1 270 900 988 999 1 1
SMAD4 BCL6 0 0 184 221 1 1
SMAD4 SOSTDC1 0 0 184 183 1 1
SMAD4 GALNT12 0 0 243 242 1 1
SMAD4 THOC2 435 0 0 435 1 1
SMAD4 SPTA1 0 0 134 152 1 1
SMAD4 GJA1 0 0 261 275 1 1
SMAD4 BMP8B 0 0 264 363 1 1
SMAD4 GPT 0 0 158 176 1 1
SMAD4 PHGDH 0 0 194 206 1 1
SMAD4 GDF1 0 0 245 342 1 1
SMAD4 KIAA1804 0 0 242 294 1 1
SMAD4 YES1 0 0 125 207 1 1
SMAD4 KLK4 0 0 136 172 1 1
SMAD4 ACVR1B 213 650 748 950 1 1
SMAD4 TH 0 0 112 178 1 2
SMAD4 TMED5 0 0 0 183 1 1
SMAD4 VEGFB 0 0 155 154 1 1
SMAD4 CD34 0 0 328 328 1 2
SMAD4 NGF 0 0 453 453 1 2
SMAD4 FOXF1 0 0 155 212 1 1
SMAD4 SYNGAP1 0 0 262 262 1 1
SMAD4 FBN1 0 0 392 432 1 1
SMAD4 FOXQ1 0 0 164 220 1 1
SMAD4 ZNF521 270 0 431 578 1 1
SMAD4 NR5A2 0 0 171 176 1 1
SMAD4 TGFBI 0 0 294 294 1 1
SMAD4 MXD1 0 0 183 201 1 1
SMAD4 VCAM1 0 0 217 217 1 1
SMAD4 SUMO1 270 0 896 922 1 1
SMAD4 CSF2 0 0 246 245 1 1
SMAD4 DYM 0 0 54 154 1 1
SMAD4 FBN2 0 0 257 306 1 1
SMAD4 PREX2 0 0 217 217 1 1
SMAD4 LHX3 0 0 103 269 1 1
SMAD4 HIST1H4C 0 0 170 169 1 1
SMAD4 FBN3 0 0 117 175 1 1
SMAD4 KMT2D 0 0 379 392 1 1
SMAD4 PSMD5 0 0 134 157 1 1
SMAD4 E2F4 0 900 782 978 1 1
SMAD4 NOX4 0 0 323 337 1 2
SMAD4 DROSHA 0 0 621 698 1 1
SMAD4 SDHD 0 0 182 231 1 1
SMAD4 GDF7 0 0 235 333 1 1
SMAD4 SCN5A 0 0 55 430 1 1
SMAD4 TGIF2 0 900 282 929 1 1
SMAD4 TGIF1 0 900 324 935 1 1
SMAD4 SKI 978 900 135 999 1 1
SMAD4 VIP 0 0 370 370 1 1
SMAD4 MZF1 0 0 169 214 1 1
SMAD4 COL4A2 0 0 122 266 1 1
SMAD4 NTRK2 0 0 157 229 1 1
SMAD4 CDK8 0 900 322 942 1 1
SMAD4 GNAI2 0 0 66 158 1 1
SMAD4 TSHR 0 0 124 161 1 1
SMAD4 DKK3 76 0 260 287 1 1
SMAD4 ADAMTS4 0 0 134 167 1 1
SMAD4 CD44 0 0 460 459 1 2
SMAD4 BDNF 0 0 215 215 1 2
SMAD4 SIX1 0 0 249 272 1 1
SMAD4 LTBP4 0 0 207 224 1 1
SMAD4 MYF6 0 0 151 249 1 1
SMAD4 PAFAH1B1 0 0 95 169 1 1
SMAD4 EYA3 0 0 0 173 1 1
SMAD4 NOV 0 0 140 158 1 1
SMAD4 DCK 0 0 141 190 1 1
SMAD4 PSG9 130 0 66 152 1 1
SMAD4 EPHB6 0 0 113 174 1 1
SMAD4 SMARCD1 0 0 85 229 1 1
SMAD4 YBX1 0 0 203 225 1 1
SMAD4 EYA1 0 0 119 275 1 1
SMAD4 CCNT2 0 900 0 903 1 1
SMAD4 DDX3X 0 0 107 193 1 1
SMAD4 ACVR2A 0 650 662 946 1 1
SMAD4 GPC1 0 0 181 234 1 1
SMAD4 HERC6 0 0 0 174 1 1
SMAD4 BRE 0 0 394 416 1 1
SMAD4 COA8 0 0 280 292 1 1
SMAD4 MMP7 0 0 370 403 1 1
SMAD4 MUTYH 0 0 609 609 1 1
SMAD4 VCL 0 0 210 230 1 1
SMAD4 NME1 0 0 241 240 1 1
SMAD4 FAM83G 0 0 255 254 1 1
SMAD4 KMT2A 0 0 145 158 1 1
SMAD4 PLEKHA4 270 0 0 277 1 1
SMAD4 SFRP4 129 0 181 270 1 1
SMAD4 FGF2 0 0 465 476 1 2
SMAD4 FOXK2 0 0 108 168 1 1
SMAD4 RELB 270 0 441 574 1 2
SMAD4 SOS1 0 0 193 224 1 1
SMAD4 AXIN2 0 0 455 530 1 1
SMAD4 PTCH1 0 0 450 460 1 1
SMAD4 VWF 0 0 182 199 1 1
SMAD4 U2AF2 0 0 0 199 1 1
SMAD4 SOX5 0 0 175 199 1 1
SMAD4 HIST1H4H 0 0 170 169 1 1
SMAD4 SPRY2 0 0 181 202 1 1
SMAD4 NEDD4L 0 600 385 802 1 1
SMAD4 CCND3 0 0 257 262 1 1
SMAD4 SOCS1 0 0 282 292 1 1
SMAD4 SYNE1 0 0 244 264 1 1
SMAD4 BTK 0 0 134 193 1 1
SMAD4 PPP2R1A 0 0 182 209 1 1
SMAD4 MAPK1 213 0 393 570 1 2
SMAD4 IGF1 0 0 457 457 1 2
SMAD4 CSF1R 0 0 401 413 1 1
SMAD4 PLA2G3 0 0 397 396 1 1
SMAD4 APBA1 0 0 206 206 1 1
SMAD4 SDC4 0 0 142 161 1 1
SMAD4 PKM 0 0 360 360 1 1
SMAD4 ESRRB 0 0 203 226 1 1
SMAD4 GADD45A 0 0 213 328 1 1
SMAD4 EPHB4 0 0 166 237 1 1
SMAD4 SKIV2L2 0 0 0 188 1 1
SMAD4 KRT20 0 0 244 243 1 1
SMAD4 FAM46A 0 0 334 334 1 1
SMAD4 KLF1 0 0 134 181 1 1
SMAD4 SPAM1 0 0 122 176 1 1
SMAD4 EIF4E 0 0 236 243 1 2
SMAD4 PPP2CA 0 0 91 175 1 1
SMAD4 ETV6 0 0 151 156 1 1
SMAD4 HIST2H2BE 0 0 165 165 1 1
SMAD4 RANBP3 0 0 141 235 1 1
SMAD4 HIVEP1 0 0 307 483 1 1
SMAD4 HEY1 0 0 294 294 1 1
SMAD4 OLIG2 0 0 193 193 1 1
SMAD4 KAT2B 0 900 260 929 1 1
SMAD4 ATPIF1 0 0 347 347 1 1
SMAD4 GPC6 0 0 123 180 1 1
SMAD4 ACTA2 0 0 315 538 1 1
SMAD4 NR5A1 0 0 150 208 1 1
SMAD4 NOS3 0 0 233 249 1 2
SMAD4 JUND 213 0 242 395 1 1
SMAD4 PRKAA1 0 0 94 167 1 2
SMAD4 FLI1 0 0 419 438 1 1
SMAD4 MEIS1 0 0 103 154 1 1
SMAD4 CCND1 0 900 602 958 1 2
SMAD4 FSHR 0 0 202 234 1 1
SMAD4 UBE2I 692 900 684 990 1 1
SMAD4 FGF5 0 0 151 266 1 1
SMAD4 WNT9A 0 0 256 540 1 1
SMAD4 FAM132B 0 0 260 266 1 1
SMAD4 TMX3 0 0 49 158 1 1
SMAD4 SGCZ 0 0 66 201 1 1
SMAD4 IRAK2 0 0 93 224 1 1
SMAD4 ALPL 0 0 193 198 1 1
SMAD4 SDPR 0 0 107 167 1 1
SMAD4 PHLPP2 0 0 212 304 1 1
SMAD4 MAP2K2 0 0 202 269 1 1
SMAD4 PPP2R5E 0 0 63 171 1 1
SMAD4 HIST2H4B 0 0 170 169 1 1
SMAD4 MDK 0 0 70 213 1 1
SMAD4 PALLD 0 0 194 194 1 1
SMAD4 NR1D1 0 0 54 157 1 2
SMAD4 CDX4 0 0 103 223 1 1
SMAD4 RHEB 0 0 150 282 1 2
SMAD4 KLF9 0 0 129 151 1 1
SMAD4 TRPS1 0 0 103 213 1 1
SMAD4 GNB2L1 0 0 187 187 1 1
SMAD4 COL7A1 0 0 103 222 1 1
SMAD4 LDLR 0 0 195 205 1 2
SMAD4 RUNX1 0 900 122 917 1 2
SMAD4 MYCBP2 0 0 92 319 1 1
SMAD4 COL6A3 0 0 171 190 1 1
SMAD4 SAV1 0 0 204 223 1 1
SMAD4 CCNK 0 900 0 902 1 1
SMAD4 PECAM1 0 0 325 325 1 1
SMAD4 UBB 128 600 0 642 1 1
SMAD4 ARID4A 0 0 0 173 1 1
SMAD4 SPINK1 0 0 180 180 1 1
SMAD4 NKX2-5 677 900 325 980 1 1
SMAD4 PTK2B 0 0 158 176 1 1
SMAD4 LRP6 0 0 310 360 1 1
SMAD4 ENSG00000264813 0 0 241 250 1 1
SMAD4 BMP5 0 0 459 650 1 1
SMAD4 PLA2G12B 0 0 0 402 1 1
SMAD4 FSTL1 0 0 137 161 1 1
SMAD4 MAP4K3 0 0 103 162 1 1
SMAD4 CCNE1 0 0 381 428 1 1
SMAD4 SAP18 0 900 67 902 1 1
SMAD4 FOXP4 0 0 66 210 1 1
SMAD4 TXN 0 0 155 174 1 1
SMAD4 SFRP5 0 0 161 176 1 1
SMAD4 EIF4A1 0 0 98 244 1 1
SMAD4 RPL19 0 0 151 150 1 1
SMAD4 SNAI2 0 0 646 749 1 1
SMAD4 PPP2R1B 0 0 184 211 1 1
SMAD4 CCL2 0 0 319 319 1 2
SMAD4 CDC23 0 0 48 168 1 1
SMAD4 ALB 0 0 467 548 1 2
SMAD4 CD68 0 0 181 181 1 2
SMAD4 DUSP9 0 0 150 185 1 1
SMAD4 ZMYM4 0 0 0 182 1 1
SMAD4 GTF2IRD1 0 0 112 173 1 1
SMAD4 CUL1 0 0 339 362 1 1
SMAD4 MME 0 0 129 177 1 1
SMAD4 CASP7 0 0 159 187 1 1
SMAD4 CSNK1D 270 0 71 334 1 1
SMAD4 XPO4 0 0 163 195 1 1
SMAD4 ELAVL1 0 0 181 201 1 2
SMAD4 LEF1 270 800 980 997 1 1
SMAD4 PDGFRB 0 0 325 339 1 2
SMAD4 NUMB 0 0 234 289 1 1
SMAD4 EP300 874 900 986 999 1 2
SMAD4 PRMT6 0 0 0 157 1 1
SMAD4 CHD1 0 0 166 226 1 1
SMAD4 WNT9B 0 0 252 538 1 1
SMAD4 IL4 0 0 298 298 1 1
SMAD4 PRMT3 0 0 0 157 1 1
SMAD4 ELMO1 0 0 150 169 1 1
SMAD4 SPARC 0 0 288 298 1 2
SMAD4 ONECUT1 0 0 290 305 1 1
SMAD4 SMAD3 998 900 989 999 1 2
SMAD4 BIRC3 0 0 154 179 1 1
SMAD4 HOXA2 0 0 113 169 1 1
SMAD4 ROCK1 0 0 293 386 1 2
SMAD4 NEK10 192 0 0 192 1 1
SMAD4 SCT 0 0 157 156 1 1
SMAD4 HNF1B 0 0 450 450 1 1
SMAD4 MORC3 0 0 74 160 1 1
SMAD4 ACTC1 0 0 108 259 1 1
SMAD4 SIRT6 0 0 204 239 1 2
SMAD4 WNT16 0 0 255 272 1 1
SMAD4 USP32 0 0 166 316 1 1
SMAD4 VPS35 0 0 0 158 1 2
SMAD4 PDGFRA 0 0 492 513 1 1
SMAD4 ALCAM 0 0 171 171 1 1
SMAD4 CDH1 0 900 729 972 1 2
SMAD4 WAC 0 0 140 239 1 1
SMAD4 IDH1 0 0 508 508 1 1
SMAD4 PRKCZ 0 0 107 177 1 1
SMAD4 NODAL 0 650 371 800 1 1
SMAD4 GATA1 0 0 233 327 1 1
SMAD4 MAP3K11 0 0 442 481 1 1
SMAD4 H3F3B 0 0 127 187 1 1
SMAD4 GLMN 0 0 142 182 1 1
SMAD4 NAV2 0 0 185 203 1 1
SMAD4 LOXL2 0 0 234 234 1 1
SMAD4 EREG 0 0 181 181 1 1
SMAD4 SMARCE1 0 0 95 163 1 1
SMAD4 MAF 0 0 260 260 1 1
SMAD4 MAGI3 0 0 0 207 1 1
SMAD4 ACVR2B 0 650 758 961 1 1
SMAD4 CRYGC 0 0 163 163 1 1
SMAD4 ALK 0 0 604 731 1 2
SMAD4 PPP1CB 0 0 59 164 1 1
SMAD4 ROCK2 0 0 145 267 1 1
SMAD4 WNT1 0 0 404 651 1 2
SMAD4 PAX6 270 0 294 472 1 1
SMAD4 SKOR2 0 0 327 430 1 1
SMAD4 MMP16 0 0 108 218 1 1
SMAD4 CEACAM8 0 0 447 447 1 1
SMAD4 EFEMP2 0 0 253 269 1 1
SMAD4 VEZF1 0 0 57 177 1 1
SMAD4 PSMD11 130 0 67 153 1 1
SMAD4 FBXO11 0 0 155 289 1 1
SMAD4 COL4A1 0 0 182 316 1 1
SMAD4 CCR1 0 0 206 219 1 1
SMAD4 FSTL3 213 0 298 425 1 1
SMAD4 PPP2CB 129 0 134 249 1 1
SMAD4 ABL2 0 0 90 152 1 1
SMAD4 PTK2 0 0 358 372 1 2
SMAD4 SAMD1 0 0 450 462 1 1
SMAD4 FRZB 0 0 235 249 1 1
SMAD4 BMP1 0 0 341 368 1 1
SMAD4 MAPK8 0 800 606 920 1 2
SMAD4 ZNF217 0 0 284 345 1 1
SMAD4 MUT 0 0 309 333 1 1
SMAD4 PRKAR1B 213 0 0 324 1 1
SMAD4 FGF18 0 0 124 273 1 1
SMAD4 CTDSPL 0 0 64 168 1 1
SMAD4 BRAF 0 0 306 358 1 2
SMAD4 MAP2K4 0 0 501 512 1 1
SMAD4 API5 0 0 180 386 1 1
SMAD4 PPP3R2 118 0 82 189 1 1
SMAD4 TRAF6 0 0 422 452 1 2
SMAD4 FLCN 0 0 208 208 1 1
SMAD4 ZZZ3 0 0 0 153 1 1
SMAD4 VCAN 0 0 195 195 1 1
SMAD4 RAC3 0 0 102 155 1 2
SMAD4 SRRT 0 0 141 163 1 1
SMAD4 PDP1 0 0 55 375 1 1
SMAD4 CXCL11 0 0 310 309 1 1
SMAD4 DUSP12 0 0 107 159 1 1
SMAD4 CYCS 0 0 238 237 1 2
SMAD4 GADD45B 0 0 425 447 1 1
SMAD4 BMP2 0 650 847 989 1 1
SMAD4 PROC 0 900 0 901 1 1
SMAD4 CTIF 0 0 137 301 1 1
SMAD4 EGF 0 0 594 606 1 2
SMAD4 HNF1A 0 900 173 913 1 1
SMAD4 SENP1 0 0 170 188 1 1
SMAD4 PLAU 0 0 261 272 1 1
SMAD4 SMARCA2 0 0 161 161 1 1
SMAD4 MUC16 0 0 193 193 1 1
SMAD4 ETV5 0 0 155 182 1 1
SMAD4 GATA4 0 900 968 997 1 2
SMAD4 HSPA4 0 0 195 195 1 1
SMAD4 PLAUR 0 0 213 213 1 1
SMAD4 PTPRK 0 0 155 210 1 1
SMAD4 DICER1 0 0 408 506 1 1
SMAD4 PIK3R1 0 0 391 419 1 1
SMAD4 CCR2 0 0 182 195 1 2
SMAD4 COL4A4 0 0 46 202 1 1
SMAD4 PDCD4 0 0 606 615 1 2
SMAD4 HSPB3 0 0 170 169 1 1
SMAD4 XPO5 72 0 457 497 1 1
SMAD4 HSP90B1 0 0 84 208 1 1
SMAD4 KPNA7 0 0 107 230 1 1
SMAD4 RBM47 0 0 0 199 1 1
SMAD4 TEK 0 0 281 295 1 1
SMAD4 PPARA 0 0 510 525 1 2
SMAD4 CDH17 0 0 370 380 1 1
SMAD4 GZMA 0 0 92 188 1 1
SMAD4 NTHL1 0 0 278 295 1 1
SMAD4 CYP19A1 0 0 261 273 1 2
SMAD4 KCNK3 0 0 234 250 1 1
SMAD4 TBX20 0 0 170 262 1 1
SMAD4 DHX15 0 0 0 231 1 1
SMAD4 SCN3A 0 0 0 175 1 1
SMAD4 ASF1A 0 0 0 156 1 1
SMAD4 JUN 411 900 980 998 1 2
SMAD4 CTDSP2 0 0 82 208 1 1
SMAD4 MAPK8IP2 0 0 500 500 1 1
SMAD4 TYK2 0 0 156 214 1 1
SMAD4 DAPK1 0 0 181 181 1 2
SMAD4 FZD1 0 0 195 260 1 1
SMAD4 DNTT 0 0 232 231 1 1
SMAD4 CCNA2 0 0 323 352 1 1
SMAD4 FZD10 0 0 202 266 1 1
SMAD4 NCOA2 0 900 100 906 1 1
SMAD4 PHF12 0 0 46 164 1 1
SMAD4 USB1 72 0 520 536 1 1
SMAD4 ERBB4 0 0 549 580 1 1
SMAD4 EIF4ENIF1 0 0 0 181 1 1
SMAD4 PIK3CG 0 0 241 306 1 1
SMAD4 JAK3 0 0 457 498 1 1
SMAD4 PUM2 0 0 0 206 1 1
SMAD4 ZBTB7A 270 0 228 428 1 1
SMAD4 MFN1 0 0 0 156 1 2
SMAD4 SMAD1 900 900 936 996 1 2
SMAD4 APBB1 0 0 287 286 1 1
SMAD4 BTG1 0 0 0 167 1 1
SMAD4 IRS2 0 0 167 173 1 1
SMAD4 BMP6 0 0 652 774 1 1
SMAD4 ID4 0 0 263 263 1 1
SMAD4 KRT8 0 0 292 292 1 1
SMAD4 COL3A1 0 0 390 515 1 1
SMAD4 NEDD9 0 0 207 213 1 1
SMAD4 PRKACB 0 0 119 179 1 1
SMAD4 ZNF800 0 0 0 161 1 1
SMAD4 NCOA3 0 0 303 303 1 1
SMAD4 QRSL1 0 0 81 289 1 1
SMAD4 IRF6 0 0 173 173 1 1
SMAD4 RSBN1 0 0 0 241 1 1
SMAD4 RUNX3 0 900 457 945 1 1
SMAD4 FYN 0 0 158 237 1 1
SMAD4 MAX 270 900 105 930 1 2
SMAD4 GRB2 0 0 321 344 1 1
SMAD4 CDC14B 170 0 0 184 1 1
SMAD4 FST 0 0 557 654 1 1
SMAD4 JAG1 0 0 451 502 1 1
SMAD4 TBL1X 0 0 194 242 1 1
SMAD4 KPNA2 0 900 82 912 1 1
SMAD4 ARNT 0 900 193 916 1 2
SMAD4 BMI1 0 0 325 420 1 1
SMAD4 SMC3 0 0 66 170 1 1
SMAD4 FGF6 0 0 114 277 1 1
SMAD4 SOX17 0 0 324 344 1 1
SMAD4 CENPE 0 0 115 170 1 1
SMAD4 CITED1 192 900 795 982 1 1
SMAD4 SPTBN1 270 0 276 537 1 1
SMAD4 WISP2 0 0 141 200 1 1
SMAD4 SOST 0 0 284 284 1 1
SMAD4 RASL12 129 0 46 152 1 1
SMAD4 HOXD10 0 0 242 291 1 1
SMAD4 PTPRC 0 0 297 311 1 1
SMAD4 MIXL1 0 0 294 345 1 1
SMAD4 GDF3 0 0 194 301 1 1
SMAD4 ITGAV 0 0 231 247 1 1
SMAD4 SF3B2 0 0 0 203 1 1
SMAD4 CCNB2 0 0 108 171 1 1
SMAD4 ICAM1 0 0 262 262 1 2
SMAD4 ROBO1 0 0 173 183 1 1
SMAD4 SOX9 0 0 616 659 1 1
SMAD4 FOXA3 0 0 167 237 1 1
SMAD4 SAR1A 0 0 71 507 1 1
SMAD4 NEUROG1 0 0 216 216 1 1
SMAD4 GNRH1 0 0 193 235 1 1
SMAD4 AR 270 900 937 995 1 2
SMAD4 ASXL1 0 0 181 262 1 1
SMAD4 SOX8 0 0 103 202 1 1
SMAD4 KIAA1468 0 0 74 159 1 1
SMAD4 SPP1 0 0 422 433 1 2
SMAD4 CDKN1A 632 900 519 981 1 2
SMAD4 RPL24 0 0 0 157 1 1
SMAD4 TIMP1 0 0 423 432 1 1
SMAD4 AURKA 0 0 279 288 1 2
SMAD4 CITED2 0 0 339 339 1 1
SMAD4 HOXA5 0 0 122 177 1 1
SMAD4 FGF1 0 0 241 286 1 1
SMAD4 PRDM14 0 600 125 658 1 1
SMAD4 CCL15 0 0 142 160 1 1
SMAD4 SLC11A2 0 0 211 223 1 1
SMAD4 JUNB 276 900 182 939 1 1
SMAD4 TFDP1 0 900 103 909 1 1
SMAD4 SQSTM1 128 0 155 231 1 2
SMAD4 MMP9 0 0 523 543 1 2
SMAD4 GTF2I 0 0 144 286 1 1
SMAD4 MAPK3 0 0 556 617 1 2
SMAD4 KLF15 0 0 141 163 1 1
SMAD4 THY1 0 0 252 252 1 1
SMAD4 HDAC4 0 0 307 333 1 2
SMAD4 ZMYM2 130 0 0 257 1 1
SMAD4 E2F7 0 0 150 159 1 1
SMAD4 S100A11 0 0 180 179 1 1
SMAD4 CTBP1 0 900 282 927 1 1
SMAD4 POFUT1 0 0 95 183 1 1
SMAD4 HSP90AA1 0 0 268 463 1 2
SMAD4 PSEN1 0 0 453 453 1 2
SMAD4 TP73 0 0 143 185 1 2
SMAD4 ATF2 270 900 453 960 1 1
SMAD4 RANGAP1 0 0 135 175 1 1
SMAD4 CFC1 0 650 124 706 1 1
SMAD4 SOX2 0 600 469 801 1 2
SMAD4 STK11IP 314 900 602 970 1 1
SMAD4 BAG3 0 0 47 186 1 2
SMAD4 ISL1 0 0 240 253 1 1
SMAD4 POSTN 0 0 269 269 1 1
SMAD4 FZD4 0 0 166 233 1 1
SMAD4 NEDD4 0 0 243 416 1 2
SMAD4 SGCD 0 0 95 240 1 1
SMAD4 RAB5A 0 0 138 233 1 2
SMAD4 BTG4 0 0 0 195 1 1
SMAD4 BMP15 0 0 315 403 1 1
SMAD4 DLX4 270 0 95 333 1 1
SMAD4 SUMO2 0 0 227 281 1 1
SMAD4 NDRG1 0 0 150 171 1 1
SMAD4 CXCL8 0 0 378 378 1 2
SMAD4 LEFTY1 0 0 342 482 1 1
SMAD4 UBE2G1 0 0 0 205 1 1
SMAD4 WNT7A 0 0 324 340 1 1
SMAD4 KLK3 0 0 244 255 1 1
SMAD4 PAX2 0 0 202 225 1 1
SMAD4 FSHB 0 0 145 276 1 1
SMAD4 GBX2 0 0 94 151 1 1
SMAD4 IL6R 0 0 193 193 1 1
SMAD4 CTNNB1 270 900 986 999 1 2
SMAD4 MSH6 0 0 608 617 1 1
SMAD4 HRAS 129 0 829 866 1 2
SMAD4 MYF5 0 0 242 329 1 1
SMAD4 MFN2 0 0 0 174 1 2
SMAD4 APP 63 0 790 799 1 2
SMAD4 EGR1 0 0 324 345 1 2
SMAD4 VENTX 0 0 74 188 1 1
SMAD4 MTSS1 0 0 138 156 1 1
SMAD4 TGFBRAP1 270 900 885 990 1 1
SMAD4 NEO1 0 0 245 297 1 1
SMAD4 WNT2B 0 0 261 435 1 1
SMAD4 DDR2 0 0 450 450 1 1
SMAD4 WWC2 0 0 0 180 1 1
SMAD4 KLC3 0 0 293 304 1 1
SMAD4 KRT17 0 0 162 181 1 1
SMAD4 MARK4 0 0 134 154 1 1
SMAD4 HIST1H4F 270 0 171 368 1 1
SMAD4 CXCR4 0 0 371 381 1 2
SMAD4 CYR61 0 0 219 219 1 1
SMAD4 KLF17 0 0 155 177 1 1
SMAD4 ZXDB 0 0 113 181 1 1
SMAD4 MMP1 0 0 284 311 1 1
SMAD4 TRAPPC8 0 0 0 209 1 1
SMAD4 RNF138 0 0 0 329 1 1
SMAD4 ARAF 0 0 248 304 1 1
SMAD4 MTOR 226 0 446 561 1 2
SMAD4 RAD51 0 0 194 211 1 2
SMAD4 TIMP4 0 0 96 191 1 1
SMAD4 MED15 270 900 328 949 1 1
SMAD4 E2F2 0 0 194 223 1 1
SMAD4 PSMC6 0 0 95 228 1 1
SMAD4 ETS2 0 0 211 237 1 1
SMAD4 ACAN 0 0 324 336 1 1
SMAD4 CXXC1 0 0 138 248 1 1
SMAD4 SMN1 0 0 377 411 1 1
SMAD4 BICC1 0 0 445 445 1 1
SMAD4 PIK3C3 0 0 103 200 1 2
SMAD4 CTRL 0 0 163 176 1 2
SMAD4 TBL1XR1 0 0 91 193 1 1
SMAD4 GNA13 0 0 81 178 1 1
SMAD4 STAT1 0 0 348 367 1 2
SMAD4 RAD51C 0 0 341 349 1 1
SMAD4 BCL2L2-PABPN1 0 0 166 184 1 1
SMAD4 TRIM71 0 0 123 150 1 1
SMAD4 GZMB 0 0 144 157 1 1
SMAD4 NPHS1 0 0 126 156 1 1
SMAD4 THRA 0 0 533 546 1 1
SMAD4 PLEK 0 0 163 163 1 1
SMAD4 OCLN 128 0 324 385 1 1
SMAD4 HFE2 0 0 796 798 1 1
SMAD4 ENSG00000257184 0 0 0 410 1 1
SMAD4 RECK 0 0 284 296 1 1
SMAD4 UBE2D3 0 900 47 908 1 1
SMAD4 SDHB 0 0 285 284 1 1
SMAD4 RSPO2 0 0 216 216 1 1
SMAD4 MSANTD3 160 0 0 159 1 1
SMAD4 GDF9 0 0 334 420 1 1
SMAD4 CREBBP 462 900 608 992 1 1
SMAD4 DGCR8 0 0 305 334 1 1
SMAD4 APC 0 0 464 841 1 1
SMAD4 WWP1 270 0 343 614 1 1
SMAD4 FGF14 0 0 0 206 1 1
SMAD4 USP9X 486 800 465 945 1 1
SMAD4 CREB1 0 0 392 421 1 2
SMAD4 ZDHHC17 0 0 0 193 1 1
SMAD4 SLC25A6 0 0 0 161 1 1
SMAD4 RHOJ 129 0 112 211 1 1
SMAD4 CTNND1 0 0 181 198 1 1
SMAD4 HOPX 0 0 935 936 1 1
SMAD4 CLDN18 0 0 187 187 1 1
SMAD4 SIRT2 0 0 184 264 1 2
SMAD4 TRIP12 0 0 0 247 1 1
SMAD4 TTC4 0 0 159 284 1 1
SMAD4 IL1RAPL1 0 0 154 153 1 1
SMAD4 WNT11 0 0 297 313 1 1
SMAD4 ZGLP1 0 0 0 159 1 1
SMAD4 WIF1 0 0 249 265 1 1
SMAD4 PTPN14 0 0 150 167 1 1
SMAD4 GNRHR 0 0 162 230 1 1
SMAD4 P2RY8 0 0 0 150 1 1
SMAD4 BUB1 0 0 156 155 1 1
SMAD4 PIWIL2 0 0 460 465 1 1
SMAD4 HOXB9 0 0 144 200 1 1
SMAD4 MMP20 0 0 60 218 1 1
SMAD4 PCLO 0 0 60 305 1 1
SMAD4 ZIC1 129 0 118 219 1 1
SMAD4 STAT4 0 0 143 278 1 1
SMAD4 KLF6 0 0 209 229 1 1
SMAD4 NFKB1 94 0 253 389 1 2
SMAD4 RELA 131 0 322 393 1 2
SMAD4 CARM1 0 0 91 160 1 2
SMAD4 PML 0 0 143 169 1 2
SMAD4 FGFR2 0 0 564 597 1 1
SMAD4 TMED7 0 0 0 183 1 1
SMAD4 WWC1 0 0 122 249 1 1
SMAD4 HDGF 128 0 91 191 1 1
SMAD4 GAPDH 0 0 604 631 1 2
SMAD4 GREM1 0 0 561 566 1 1
SMAD4 DUSP5 0 0 106 180 1 1
SMAD4 TCF7L2 0 0 425 724 1 1
SMAD4 HAMP 0 0 556 568 1 1
SMAD4 SPDEF 0 0 91 159 1 1
SMAD4 ABL1 0 0 458 495 1 1
SMAD4 ZNF410 0 0 84 163 1 1
SMAD4 HIST4H4 0 0 170 169 1 1
SMAD4 EBF1 0 0 161 167 1 1
SMAD4 MAP2K7 0 0 517 532 1 1
SMAD4 CRIM1 0 0 134 190 1 1
SMAD4 PPP5C 0 0 0 179 1 1
SMAD4 MATN2 0 0 94 154 1 1
SMAD4 IL15 0 0 147 165 1 1
SMAD4 RALGDS 0 0 188 200 1 1
SMAD4 APC2 0 0 0 421 1 1
SMAD4 SOX11 0 0 166 191 1 1
SMAD4 IFNA1 0 0 153 152 1 1
SMAD4 NR0B2 131 0 92 201 1 1
SMAD4 WNT5A 0 0 393 498 1 2
SMAD4 ILK 0 0 324 344 1 1
SMAD4 FA2H 0 0 0 162 1 1
SMAD4 TRIM33 870 600 896 994 1 1
SMAD4 PPARGC1A 0 0 184 183 1 2
SMAD4 ADAM10 0 0 142 210 1 1
SMAD4 RICTOR 0 0 218 240 1 2
SMAD4 EDC4 0 0 270 285 1 1
SMAD4 IBSP 0 0 286 296 1 1
SMAD4 USP15 675 0 292 793 1 1
SMAD4 SCN2A 0 0 49 182 1 1
SMAD4 GNAQ 0 0 457 482 1 1
SMAD4 TBX5 0 0 232 260 1 1
SMAD4 DVL1 270 0 282 544 1 1
SMAD4 PIK3R3 0 0 171 209 1 1
SMAD4 CEACAM5 0 0 392 392 1 1
SMAD4 TOP1 0 0 180 179 1 1
SMAD4 WWTR1 0 800 460 905 1 1
SMAD4 IL2RA 0 0 95 243 1 1
SMAD4 ACP5 0 0 170 169 1 1
SMAD4 TTN 0 0 218 218 1 1
SMAD4 FLNA 0 0 226 263 1 1
SMAD4 LRP5 0 0 325 374 1 1
SMAD4 DLX2 0 0 195 224 1 1
SMAD4 CHGA 0 0 219 219 1 1
SMAD4 CCNT1 0 900 44 901 1 1
SMAD4 PBK 128 0 97 235 1 1
SMAD4 INHBA 0 650 342 790 1 1
SMAD4 LRP1B 0 0 324 333 1 1
SMAD4 MTA1 0 0 140 184 1 1
SMAD4 LEMD3 0 0 439 578 1 1
SMAD4 RCOR3 0 0 0 172 1 1
SMAD4 VPS39 0 0 701 701 1 1
SMAD4 ACTA1 0 0 203 280 1 1
SMAD4 NKX6-1 0 0 108 220 1 1
SMAD4 MYL9 0 0 113 158 1 1
SMAD4 TDGF1 0 650 425 808 1 1
SMAD4 RB1CC1 0 0 94 173 1 2
SMAD4 MARCH7 0 0 49 666 1 1
SMAD4 FRS2 0 0 171 171 1 1
SMAD4 SND1 0 0 125 160 1 1
SMAD4 NFIX 259 0 357 503 1 1
SMAD4 PDGFB 0 0 295 295 1 2
SMAD4 PITX1 0 0 134 165 1 1
SMAD4 BRCA1 213 0 557 636 1 2
SMAD4 STK11 0 900 727 974 1 2
SMAD4 PAX9 0 0 158 157 1 1
SMAD4 KRT4 0 0 171 171 1 1
SMAD4 AREG 0 0 283 282 1 1
SMAD4 TCF3 0 900 181 919 1 1
SMAD4 SLC29A1 0 0 194 194 1 1
SMAD4 FZD2 0 0 123 194 1 1
SMAD4 CDKN2D 0 0 146 160 1 1
SMAD4 TP53 0 0 805 817 1 2
SMAD4 MDM2 0 0 465 477 1 2
SMAD4 HOXA13 0 0 332 376 1 1
SMAD4 HECTD2 0 0 0 193 1 1
SMAD4 DCN 0 0 398 409 1 2
SMAD4 SOX18 0 0 150 183 1 1
SMAD4 CTNNA1 0 0 244 260 1 1
SMAD4 LRIG1 0 0 118 178 1 1
SMAD4 TGM2 0 0 204 204 1 2
SMAD4 FLNB 0 0 134 175 1 1
SMAD4 SATB2 0 0 162 161 1 1
SMAD4 FGFR3 0 0 520 557 1 1
SMAD4 HOXB4 0 0 113 169 1 1
SMAD4 CHCHD2 0 0 433 433 1 1
SMAD4 LAMP1 0 0 378 389 1 2
SMAD4 SLC2A1 0 0 181 203 1 2
SMAD4 AMHR2 0 0 391 445 1 1
SMAD4 LHX1 0 0 174 188 1 1
SMAD4 EGFR 0 0 670 693 1 2
SMAD4 CFLAR 0 0 212 212 1 2
SMAD4 MAP3K13 0 0 553 553 1 1
SMAD4 PPP1CC 0 0 129 234 1 1
SMAD4 CD2BP2 0 0 0 191 1 1
SMAD4 NCOR2 0 600 138 659 1 1
SMAD4 IRAK1 0 0 273 327 1 1
SMAD4 ME2 0 0 268 349 1 1
SMAD4 HOXC13 0 0 74 166 1 1
SMAD4 RAF1 0 0 254 316 1 2
SMAD4 ADAMTS1 0 0 138 176 1 1
SMAD4 RBL1 270 900 712 978 1 1
SMAD4 CUL2 0 0 144 205 1 1
SMAD4 FPGS 0 0 55 157 1 1
SMAD4 TLX1 0 0 70 184 1 1
SMAD4 RREB1 0 0 180 230 1 1
SMAD4 MXD4 0 0 155 174 1 1
SMAD4 MAP3K7 0 0 502 599 1 2
SMAD4 KPNA3 0 0 94 167 1 1
SMAD4 HDAC2 78 900 283 936 1 1
SMAD4 NUP153 0 900 454 948 1 1
SMAD4 CHAF1B 275 0 0 275 1 1
SMAD4 WNT4 0 0 322 439 1 1
SMAD4 EDA 0 0 203 214 1 1
SMAD4 HOXC9 0 0 459 506 1 1
SMAD4 VPS4B 0 0 53 334 1 1
SMAD4 PAEP 0 0 419 418 1 1
SMAD4 TNFRSF11B 0 0 234 234 1 1
SMAD4 JAK2 0 0 458 506 1 2
SMAD4 HDAC6 0 0 194 224 1 2
SMAD4 APAF1 0 0 181 198 1 2
SMAD4 CDH2 0 0 566 575 1 1
SMAD4 BRD4 0 0 156 245 1 2
SMAD4 HUWE1 0 0 118 241 1 1
SMAD4 CLU 0 0 147 166 1 2
SMAD4 RNF111 0 600 464 784 1 1
SMAD4 NR4A1 0 0 171 171 1 2
SMAD4 CDH3 0 0 241 264 1 1
SMAD4 KLF10 0 0 322 354 1 1
SMAD4 PPARD 0 900 108 912 1 1
SMAD4 PTPRT 0 0 160 198 1 1
SMAD4 ITGA5 0 0 210 219 1 1
SMAD4 UBR5 0 0 67 302 1 1
SMAD4 MMP15 0 0 74 232 1 1
SMAD4 KRT5 0 0 266 266 1 1
SMAD4 PRKAR2A 213 0 0 332 1 1
SMAD4 SERPINH1 0 0 146 161 1 1
SMAD4 MYH6 0 0 202 208 1 1
SMAD4 MUC5AC 0 900 455 944 1 1
SMAD4 TCEA1 0 0 257 257 1 1
SMAD4 SOX4 0 0 691 700 1 1
SMAD4 EIF2AK4 128 0 674 710 1 2
SMAD4 RBMS1 0 0 96 226 1 1
SMAD4 GDNF 0 0 180 196 1 2
SMAD4 ITGB8 0 0 173 191 1 1
SMAD4 FANCC 129 0 261 328 1 1
SMAD4 HBEGF 0 0 218 218 1 1
SMAD4 TRIM8 0 0 124 151 1 1
SMAD4 NCOA1 0 900 122 908 1 1
SMAD4 NTRK3 0 0 201 264 1 1
SMAD4 TRIM47 270 0 61 308 1 1
SMAD4 GAPDHS 0 0 0 207 1 1
SMAD4 PDCD1LG2 0 0 155 154 1 1
SMAD4 MMP11 0 0 123 276 1 1
SMAD4 PAPOLA 0 0 63 178 1 1
SMAD4 NFATC1 0 0 270 270 1 2
SMAD4 AGO1 0 0 181 189 1 1
SMAD4 E2F5 0 900 571 957 1 1
SMAD4 TERF1 0 0 123 163 1 1
SMAD4 ACTR1A 0 0 181 224 1 1
SMAD4 FZD9 0 0 125 196 1 1
SMAD4 BMPR1A 0 650 800 968 1 1
SMAD4 FOXL1 0 0 98 159 1 1
SMAD4 RORC 0 0 134 286 1 1
SMAD4 TNFRSF9 0 0 248 248 1 1
SMAD4 HIST1H4K 0 0 170 169 1 1
SMAD4 MARK2 0 0 205 229 1 1
SMAD4 RAB27B 0 0 118 211 1 1
SMAD4 E2F3 0 0 284 317 1 1
SMAD4 NGFR 0 0 158 157 1 1
SMAD4 CDX2 0 0 459 478 1 1
SMAD4 RARB 0 0 150 193 1 1
SMAD4 NLK 355 900 170 951 1 1
SMAD4 LDHA 0 0 183 183 1 2
SMAD4 COMMD3-BMI1 0 0 325 341 1 1
SMAD4 KIT 0 0 500 510 1 2
SMAD4 NFE2L1 0 0 45 169 1 1
SMAD4 CCNA1 0 0 136 173 1 1
SMAD4 SOX10 0 0 150 354 1 1
SMAD4 ATP1B4 0 650 0 652 1 1
SMAD4 FGF12 0 0 63 214 1 1
SMAD4 MDM4 270 0 232 415 1 1
SMAD4 ENG 0 0 561 561 1 2
SMAD4 NIPA2 0 0 0 167 1 1
SMAD4 IGF2 0 0 358 358 1 1
SMAD4 TEAD1 0 0 202 281 1 1
SMAD4 MUC6 0 0 391 404 1 1
SMAD4 CRB2 0 0 0 163 1 1
SMAD4 IL10 0 0 342 342 1 2
SMAD4 SNAI1 0 0 971 976 1 1
SMAD4 FGFR4 0 0 229 288 1 1
SMAD4 UBE2S 0 0 174 188 1 1
SMAD4 HHEX 0 0 124 212 1 1
SMAD4 IRAK4 0 0 95 157 1 1
SMAD4 NPM1 0 0 404 413 1 1
SMAD4 FLT3 0 0 401 413 1 2
SMAD4 SMARCC2 0 0 70 178 1 1
SMAD4 WNT10A 0 0 270 287 1 1
SMAD4 GDF5 0 0 376 456 1 1
SMAD4 FOSB 0 0 171 189 1 1
SMAD4 DMD 0 0 113 196 1 2
SMAD4 GDF15 0 0 342 426 1 1
SMAD4 FOSL2 0 0 180 197 1 1
SMAD4 AREL1 0 0 0 174 1 1
SMAD4 PRSS58 0 0 339 349 1 1
SMAD4 TIMP2 0 0 300 300 1 1
SMAD4 SERPINB5 57 0 261 286 1 1
SMAD4 TEAD4 0 0 134 220 1 1
SMAD4 UBC 0 600 86 625 1 2
SMAD4 LDB1 0 0 75 170 1 1
SMAD4 HAND2 0 0 181 181 1 1
SMAD4 INHBC 0 0 107 222 1 1
SMAD4 COL4A6 0 0 0 198 1 1
SMAD4 NKX2-1 0 0 294 338 1 1
SMAD4 MST1R 0 0 181 237 1 1
SMAD4 TERT 0 0 405 405 1 2
SMAD4 TET2 0 0 260 260 1 2
SMAD4 VAV1 0 0 117 172 1 1
SMAD4 RARS 0 0 134 152 1 1
SMAD4 RAG2 0 0 135 198 1 1
SMAD4 FN1 209 0 619 707 1 2
SMAD4 TBP 0 0 195 211 1 1
SMAD4 MMP13 0 0 340 359 1 2
SMAD4 ESRP1 0 0 150 173 1 1
SMAD4 PRKCA 0 0 253 252 1 1
SMAD4 ACVRL1 0 0 735 754 1 1
SMAD4 UBE3B 0 0 0 192 1 1
SMAD4 DLX1 270 900 459 958 1 1
SMAD4 SETD2 0 0 244 270 1 1
SMAD4 CDC25B 0 0 113 176 1 1
SMAD4 SMAD7 875 900 977 992 1 1
SMAD4 POLD1 0 0 502 512 1 1
SMAD4 HOMER1 0 0 96 183 1 1
SMAD4 PDCD1 0 0 193 193 1 2
SMAD4 MAZ 0 0 74 163 1 1
SMAD4 MSH2 0 0 607 617 1 1
SMAD4 ESR1 213 900 958 996 1 2
SMAD4 FMNL2 0 0 55 159 1 1
SMAD4 IFNB1 0 0 162 166 1 1
SMAD4 WLS 0 0 66 152 1 1
SMAD4 SERBP1 0 0 89 152 1 1
SMAD4 LMNB1 0 0 181 218 1 1
SMAD4 OVOL1 0 0 181 198 1 1
SMAD4 TBX6 270 0 350 532 1 1
SMAD4 NKX2-3 0 0 74 282 1 2
SMAD4 RAB22A 0 0 74 163 1 1
SMAD4 EOMES 0 0 323 347 1 1
SMAD4 MYOCD 0 0 324 323 1 1
SMAD4 IFT80 0 0 0 163 1 1
SMAD4 TLE3 0 0 146 220 1 1
SMAD4 OTX2 0 0 213 213 1 1
SMAD4 YAP1 0 800 366 919 1 2
SMAD4 IRF1 0 0 180 179 1 2
SMAD4 ELN 0 0 341 341 1 1
SMAD4 FOXN2 0 0 66 203 1 1
SMAD4 KLF11 0 0 232 252 1 1
SMAD4 PRKD1 0 0 171 171 1 1
SMAD4 BMP8A 0 0 107 227 1 1
SMAD4 ILKAP 272 0 0 307 1 1
SMAD4 LGR5 0 0 390 400 1 1
SMAD4 INHA 0 0 270 364 1 1
SMAD4 SYP 0 0 206 206 1 1
SMAD4 ZNF330 0 0 76 166 1 1
SMAD4 PAK4 0 0 181 219 1 1
SMAD4 SAR1B 0 0 0 314 1 1
SMAD4 CDC25A 0 900 266 925 1 1
SMAD4 DLX5 0 0 321 339 1 1
SMAD4 SCN8A 0 0 0 175 1 1
SMAD4 MYH11 0 0 310 315 1 1
SMAD4 CTDNEP1 0 0 141 284 1 1
SMAD4 FOXC1 0 0 295 357 1 1
SMAD4 CARD11 0 0 162 171 1 1
SMAD4 BECN1 0 0 217 228 1 2
SMAD4 ABCB1 0 0 181 181 1 2
SMAD4 THBS1 0 0 457 457 1 1
SMAD4 PTF1A 0 0 490 490 1 1
SMAD4 SMARCD3 0 0 67 235 1 1
SMAD4 IL2 0 0 285 284 1 1
SMAD4 FZD3 0 0 124 194 1 1
SMAD4 TBX22 0 0 162 192 1 1
SMAD4 ITGA2 0 0 181 181 1 1
SMAD4 LRP1 0 0 430 438 1 1
SMAD4 IRX3 0 0 113 182 1 1
SMAD4 SNX4 0 0 0 173 1 2
SMAD4 MUC4 0 0 325 325 1 1
SMAD4 DUSP1 0 0 180 197 1 1
SMAD4 FLT4 0 0 209 225 1 1
SMAD4 NCCRP1 0 0 0 188 1 1
SMAD4 MAPK11 0 0 126 281 1 1
SMAD4 IPO7 0 0 218 381 1 1
SMAD4 MEX3C 0 0 218 363 1 1
SMAD4 PIAS1 417 0 729 839 1 1
SMAD4 AMH 0 0 379 463 1 1
SMAD4 MLH1 0 0 665 676 1 1
SMAD4 NELL1 0 0 103 172 1 1
SMAD4 CDKN2C 0 0 208 221 1 1
SMAD4 PPM1A 0 600 400 774 1 1
SMAD4 ZNRF3 0 0 258 286 1 1
SMAD4 FOXK1 0 0 92 160 1 1
SMAD4 ADAM15 0 0 49 292 1 1
SMAD4 ASCL1 0 0 165 165 1 1
SMAD4 DCC 0 0 333 371 1 1
SMAD4 DCP1A 768 900 721 993 1 1
SMAD4 ZIC3 0 0 134 179 1 1
SMAD4 KRAS 0 0 849 871 1 2
SMAD4 FANCG 0 0 214 214 1 1
SMAD4 HOXC8 270 0 270 515 1 1
SMAD4 DTX2 0 0 0 158 1 1
SMAD4 PTH 0 0 203 203 1 1
SMAD4 NKX3-2 270 0 450 608 1 1
SMAD4 LHX4 412 0 0 470 1 1
SMAD4 FOXD1 0 0 96 157 1 1
SMAD4 FASLG 0 0 211 211 1 1
SMAD4 KDM6B 270 0 459 604 1 1
SMAD4 SOCS3 0 0 234 245 1 1
SMAD4 GAS7 0 0 58 195 1 1
SMAD4 PRKAR1A 0 0 137 266 1 2
SMAD4 RHOD 128 0 143 237 1 1
SMAD4 STAT5A 0 0 273 315 1 1
SMAD4 RXRA 0 0 141 175 1 1
SMAD4 MMP24 0 0 66 181 1 1
SMAD4 FOXN1 0 0 142 221 1 1
SMAD4 EDC3 0 0 270 290 1 1
SMAD4 ECSIT 213 0 640 704 1 1
SMAD4 NOD2 0 0 113 171 1 2
SMAD4 TBX15 0 0 0 173 1 1
SMAD4 BANF1 0 0 150 182 1 1
SMAD4 TWIST2 0 0 259 275 1 1
SMAD4 SOX1 0 0 210 233 1 1
SMAD4 PIK3CD 0 0 75 169 1 1
SMAD4 CEBPB 675 900 957 998 1 2
SMAD4 FGF9 0 0 202 290 1 1
SMAD4 ERCC5 0 0 151 189 1 1
SMAD4 FGF11 0 0 45 221 1 1
SMAD4 WNT3 0 0 366 476 1 1
SMAD4 RIPK1 0 0 95 157 1 2
SMAD4 WWC3 0 0 0 174 1 1
SMAD4 COPS4 0 0 66 178 1 1
SMAD4 MAP3K10 0 0 432 471 1 1
SMAD4 GUSB 0 0 134 282 1 1
SMAD4 RPS27A 388 600 75 757 1 1
SMAD4 ARRB2 0 0 125 153 1 1
SMAD4 CDKN2A 0 900 757 975 1 2
SMAD4 GSK3B 0 0 342 489 1 2
SMAD4 FAT4 0 0 209 239 1 1
SMAD4 CDC34 0 0 81 208 1 1
SMAD4 KRT7 0 0 371 371 1 1
SMAD4 SALL4 0 600 162 687 1 1
SMAD4 FGF8 0 0 294 369 1 1
SMAD4 ZNF34 0 0 67 153 1 1
SMAD4 CCNG1 0 0 150 216 1 1
SMAD4 ZIC2 0 0 129 151 1 1
SMAD4 APBB2 128 0 136 214 1 1
SMAD4 INSRR 0 0 45 352 1 1
SMAD4 COL4A5 0 0 134 276 1 1
SMAD4 EPHB2 0 0 184 240 1 2
SMAD4 IHH 0 0 391 444 1 1
SMAD4 UBA2 0 0 116 179 1 1
SMAD4 LTBP3 0 0 223 240 1 1
SMAD4 PPM1B 0 0 46 180 1 1
SMAD4 ACE 0 0 243 253 1 1
SMAD4 IL13 0 0 261 261 1 2
SMAD4 TNFRSF10B 0 0 162 161 1 2
SMAD4 REN 0 0 234 234 1 1
SMAD4 RAD21 0 0 100 205 1 1
SMAD4 CYBB 0 0 150 173 1 2
SMAD4 ADAM29 0 0 145 183 1 1
SMAD4 VEGFC 0 0 252 252 1 1
SMAD4 ENSG00000268643 0 0 0 253 1 1
SMAD4 SMARCA1 0 0 137 223 1 1
SMAD4 SAMD4A 0 0 460 459 1 1
SMAD4 ELF3 0 0 270 274 1 1
SMAD4 BRCA2 0 0 632 640 1 1
SMAD4 PARG 0 0 468 468 1 1
SMAD4 HDAC9 0 0 208 238 1 1
SMAD4 REL 0 0 262 272 1 2
SMAD4 KLC1 0 0 456 466 1 1
SMAD4 CASP3 0 0 469 480 1 2
SMAD4 ERBB3 0 0 392 434 1 1
SMAD4 DDX6 0 0 270 286 1 1
SMAD4 PTGS2 0 0 391 390 1 2
SMAD4 SMURF1 486 900 618 986 1 1
SMAD4 TGFBR3 0 0 518 526 1 1
SMAD4 RASSF1 0 0 321 321 1 1
SMAD4 NTN1 0 0 138 169 1 1
SMAD4 MMP12 0 0 143 176 1 1
SMAD4 JAK1 0 0 329 388 1 2
SMAD4 MITF 0 0 249 250 1 2
SMAD4 DMRT1 0 0 103 161 1 1
SMAD4 HAS2 0 0 260 260 1 1
SMAD4 NFATC2 0 0 181 181 1 1
SMAD4 PIAS4 675 900 694 989 1 1
SMAD4 ELK4 0 0 113 150 1 1
SMAD4 TBX4 0 0 180 209 1 1
SMAD4 TCHP 0 0 342 342 1 1
SMAD4 CD82 0 0 161 173 1 1
SMAD4 DNMT3L 270 0 112 324 1 1
SMAD4 NRG1 0 0 206 206 1 2
SMAD4 LIN28B 0 0 164 200 1 1
SMAD4 HMOX1 0 0 195 195 1 2
SMAD4 CTCF 213 900 244 938 1 1
SMAD4 STK3 0 0 0 190 1 1
SMAD4 CDKN1B 0 900 459 948 1 2
SMAD4 NUP214 270 900 685 975 1 1
SMAD4 GPC3 0 0 150 205 1 1
SMAD4 RB1 0 0 282 299 1 2
SMAD4 DCP2 0 0 57 167 1 1
SMAD4 CDA 0 0 155 154 1 1
SMAD4 AES 74 0 88 154 1 1
SMAD4 HACE1 0 0 0 184 1 1
SMAD4 TSC2 0 0 310 317 1 2
SMAD4 PPM1D 0 0 108 206 1 1
SMAD4 HECTD1 0 0 0 192 1 1
SMAD4 MSX2 0 0 424 504 1 1
SMAD4 SMURF2 486 600 687 956 1 1
SMAD4 EPHB3 0 0 135 194 1 1
SMAD4 MKL1 0 0 234 234 1 1
SMAD4 SMARCC1 0 0 90 184 1 1
SMAD4 DOCK2 0 0 166 165 1 1
SMAD4 SRC 0 0 603 640 1 2
SMAD4 ADAM12 0 0 134 188 1 1
SMAD4 ACTL6A 0 0 74 211 1 1
SMAD4 RAB25 129 0 65 316 1 2
SMAD4 KIF5B 0 0 123 171 1 1
SMAD4 LIFR 0 0 165 165 1 1
SMAD4 KDM6A 0 0 293 345 1 1
SMAD4 METTL3 0 0 74 170 1 2
SMAD4 EEA1 0 0 148 163 1 2
SMAD4 ZFPM2 0 0 155 228 1 1
SMAD4 STAT6 0 0 242 263 1 1
SMAD4 TCF12 0 0 193 268 1 1
SMAD4 EIF2AK3 0 0 292 292 1 2
SMAD4 WWP2 0 0 150 344 1 1
SMAD4 FOXJ2 0 0 90 171 1 1
SMAD4 VHL 0 0 445 445 1 2
SMAD4 FLT1 0 0 282 296 1 1
SMAD4 ROBO2 0 0 335 343 1 1
SMAD4 SLC25A5 0 0 107 219 1 1
SMAD4 LGALS3 0 0 167 189 1 2
SMAD4 ALAS2 0 0 82 156 1 1
SMAD4 TAF13 0 0 0 349 1 1
SMAD4 RHOC 0 0 228 298 1 1
SMAD4 CXCL10 0 0 150 168 1 2
SMAD4 TSC22D2 0 0 0 203 1 1
SMAD4 FGF3 0 0 205 289 1 1
SMAD4 IPO8 0 0 418 535 1 1
SMAD4 CHRD 0 0 558 794 1 1
SMAD4 GSK3A 0 0 96 295 1 1
SMAD4 ATOH1 0 0 181 181 1 1
SMAD4 ITGB6 0 0 137 175 1 1
SMAD4 BIRC5 0 0 134 152 1 2
SMAD4 USP3 0 0 66 179 1 1
SMAD4 SIRT4 0 0 166 200 1 1
SMAD4 CSMD3 0 0 230 243 1 1
SMAD4 WWOX 312 0 597 766 1 1
SMAD4 ID2 0 0 414 460 1 1
SMAD4 CCNG2 270 0 138 403 1 1
SMAD4 IL11 0 0 358 358 1 1
SMAD4 FOXE1 0 0 108 168 1 1
SMAD4 ELAC1 0 0 325 341 1 1
SMAD4 BBC3 0 0 161 161 1 2
SMAD4 CHRDL1 0 0 261 261 1 1
SMAD4 FANCD2 0 0 202 205 1 1
SMAD4 FOXF2 0 0 150 225 1 1
SMAD4 HMGA2 0 900 529 952 1 1
SMAD4 ERBB2 0 0 653 677 1 2
SMAD4 NKX2-8 0 0 123 178 1 1
SMAD4 IRF3 270 0 386 536 1 2
SMAD4 CPA1 0 0 107 168 1 1
SMAD4 NOTCH2NL 0 0 0 163 1 1
SMAD4 SRGAP3 0 0 46 151 1 1
SMAD4 IGF2R 0 0 166 166 1 1
SMAD4 CCNE2 0 0 205 293 1 1
SMAD4 MAP3K1 0 0 365 378 1 1
SMAD4 SLIT3 0 0 193 207 1 1
SMAD4 CD4 0 0 374 374 1 2
SMAD4 RRM1 0 0 134 174 1 1
SMAD4 SCN9A 0 0 0 175 1 1
SMAD4 HOXA10 0 0 126 183 1 1
SMAD4 PRDM16 0 0 372 464 1 1
SMAD4 PTHLH 0 0 322 335 1 1
SMAD4 FOXA1 0 0 324 488 1 1
SMAD4 SEPHS2 0 0 0 377 1 1
SMAD4 TEAD2 0 0 203 282 1 1
SMAD4 LHX2 0 0 180 194 1 1
SMAD4 MKI67 0 0 118 348 1 2
SMAD4 GIPC1 0 0 142 176 1 1
SMAD4 AKT1 679 0 690 929 1 2
SMAD4 TGFB2 0 900 685 972 1 1
SMAD4 UBE3A 0 0 157 323 1 1
SMAD4 PPARG 0 0 414 431 1 2
SMAD4 SLIT2 0 0 171 185 1 1
SMAD4 XIAP 0 0 283 299 1 2
SMAD4 CEBPG 0 0 73 158 1 1
SMAD4 PPP2R4 0 0 249 248 1 1
SMAD4 SPEN 0 0 46 180 1 1
SMAD4 RUNX2 0 900 889 989 1 2
SMAD4 PCBP4 0 650 0 650 1 1
SMAD4 FMOD 0 0 137 152 1 1
SMAD4 COL1A2 0 0 459 471 1 1
SMAD4 IKBKB 0 0 272 342 1 2
SMAD4 COL6A1 0 0 150 170 1 1
SMAD4 KLF4 0 600 402 757 1 2
SMAD4 SATB1 0 0 140 230 1 1
SMAD4 FGFR1 0 0 557 591 1 1
SMAD4 BRDT 0 0 64 233 1 1
SMAD4 NARS 0 0 0 192 1 1
SMAD4 TRAP1 213 0 0 354 1 2
SMAD4 SIX3 0 0 134 161 1 1
SMAD4 CCDC102B 0 0 217 217 1 1
SMAD4 PIK3R2 0 0 206 242 1 1
SMAD4 WISP1 0 0 165 165 1 1
SMAD4 VDR 0 900 217 955 1 2
SMAD4 NIPAL1 0 0 0 167 1 1
SMAD4 ASCC1 0 0 0 189 1 1
SMAD4 TDG 130 0 70 200 1 1
SMAD4 PIAS2 462 0 207 559 1 1
SMAD4 HMG20A 276 0 52 284 1 1
SMAD4 MMP3 0 0 284 350 1 1
SMAD4 ITK 128 0 74 215 1 1
SMAD4 NT5E 0 0 181 181 1 1
SMAD4 KRT14 0 0 259 258 1 1
SMAD4 PLA2G12A 0 0 398 462 1 1
SMAD4 MEF2C 0 900 453 946 1 1
SMAD4 MMP25 0 0 0 210 1 1
SMAD4 SIN3A 0 900 193 932 1 1
SMAD4 ANKRD1 0 0 355 365 1 1
SMAD4 TNF 0 0 465 488 1 2
SMAD4 MSX1 0 0 391 467 1 1
SMAD4 PDGFC 0 0 174 173 1 1
SMAD4 RBBP7 0 900 74 906 1 1
SMAD4 PPP1R15A 0 0 178 177 1 2
SMAD4 PLAG1 0 0 138 194 1 1
SMAD4 PAX3 0 0 294 294 1 1
SMAD4 ITCH 0 0 453 578 1 1
SMAD4 EEF2 0 0 55 151 1 2
SMAD4 TFAP2C 0 0 193 193 1 1
SMAD4 NFAT5 0 0 155 339 1 1
SMAD4 PEBP1 0 0 163 163 1 1
SMAD4 RGS3 0 0 90 173 1 1
SMAD4 ERCC3 0 0 123 226 1 1
SMAD4 SNAI3 0 0 150 189 1 1
SMAD4 DDX17 0 0 328 425 1 1
SMAD4 PRPF6 0 0 171 189 1 1
SMAD4 CSNK2A1 0 0 143 152 1 1
SMAD4 FHL3 270 0 0 276 1 1
SMAD4 GPNMB 72 0 391 411 1 1
SMAD4 MMP8 0 0 146 299 1 1
SMAD4 PROX1 0 0 321 321 1 1
SMAD4 NR2C2AP 0 0 95 172 1 1
SMAD4 HECW1 0 0 0 174 1 1
SMAD4 RSPO1 0 0 328 328 1 1
SMAD4 REST 0 0 150 172 1 2
SMAD4 ZNF451 0 0 448 463 1 1
SMAD4 GSTP1 0 0 177 195 1 1
SMAD4 NFKB2 0 0 166 306 1 1
SMAD4 RND3 0 0 124 202 1 1
SMAD4 TMPRSS2 0 0 236 247 1 1
SMAD4 RPS6KA2 0 0 165 165 1 1
SMAD4 IL5 0 0 170 169 1 1
SMAD4 AGT 0 0 83 242 1 1
SMAD4 TFRC 0 0 288 303 1 1
SMAD4 TFAP2A 0 0 179 185 1 1
SMAD4 LAMC1 0 0 90 170 1 1
SMAD4 CCND2 0 0 362 366 1 1
SMAD4 FHIT 0 0 459 459 1 1
SMAD4 IRF7 270 900 112 931 1 1
SMAD4 TBX18 0 0 124 202 1 1
SMAD4 FOXL2 0 0 860 869 1 1
SMAD4 DDX53 0 0 212 230 1 1
SMAD4 MMP27 0 0 0 210 1 1
SMAD4 FERMT1 0 0 113 185 1 1
SMAD4 RTKN 0 0 120 175 1 1
SMAD4 CDH5 0 0 279 291 1 1
SMAD4 ATF3 0 900 817 983 1 2
SMAD4 PARD6A 0 0 65 161 1 1
SMAD4 SCN4A 0 0 0 642 1 1
SMAD4 PRMT8 0 0 0 164 1 1
SMAD4 IRS1 0 0 245 251 1 2
SMAD4 SGK1 0 0 134 187 1 2
SMAD4 LOX 0 0 413 420 1 2
SMAD4 EGR2 0 0 180 201 1 1
SMAD4 NTRK1 0 0 325 378 1 1
SMAD4 MUC1 0 0 415 414 1 1
SMAD4 HIST1H4B 0 0 170 169 1 1
SMAD4 PGR 0 0 318 337 1 1
SMAD4 CDK1 0 0 261 277 1 2
SMAD4 NCOR1 270 900 547 965 1 1
SMAD4 SERPINE1 0 900 609 961 1 1
SMAD4 AHR 270 0 195 387 1 2
SMAD4 IDUA 0 0 0 206 1 1
SMAD4 RPS6KB1 0 0 325 413 1 2
SMAD4 HGNC:9982 130 0 95 213 1 1
SMAD4 AGTR1 0 0 250 262 1 1
SMAD4 LMO4 491 0 0 500 1 1
SMAD4 REM1 0 0 46 477 1 1
SMAD4 HDAC7 0 0 142 178 1 1
SMAD4 EPHA1 0 0 113 197 1 1
SMAD4 SAP30 0 900 60 904 1 1
SMAD4 HOXD8 0 0 72 209 1 1
SMAD4 DPYD 0 0 184 213 1 1
SMAD4 HERC3 0 0 0 196 1 1
SMAD4 HOXB7 0 0 175 227 1 1
SMAD4 ALDOC 272 0 0 272 1 1
SMAD4 CD274 0 0 342 342 1 2
SMAD4 SREBF2 0 0 95 235 1 1
SMAD4 WNT8B 0 0 243 261 1 1
SMAD4 BCL2L2 0 0 167 167 1 1
SMAD4 DVL2 0 0 211 312 1 2
SMAD4 SERPINE2 0 0 123 432 1 1
SMAD4 FOXC2 0 0 324 383 1 1
SMAD4 ABCG2 0 0 233 232 1 1
SMAD4 GREM2 0 0 228 339 1 1
SMAD4 FGF16 0 0 0 196 1 1
SMAD4 SPRY1 0 0 220 232 1 1
SMAD4 SEMA5B 0 0 123 163 1 1
SMAD4 MYB 0 0 194 214 1 1
SMAD4 OR2AG1 0 0 519 519 1 1
SMAD4 SMAD6 486 900 958 965 1 1
SMAD4 FOXA2 0 0 310 478 1 1
SMAD4 RNF38 0 0 0 189 1 1
SMAD4 TOB2 0 0 81 195 1 1
SMAD4 RNASEL 0 0 56 150 1 1
SMAD4 RBM25 0 0 0 151 1 1
SMAD4 HPRT1 0 0 218 218 1 1
SMAD4 CTLA4 0 0 307 307 1 2
SMAD4 HOXB13 0 0 155 210 1 1
SMAD4 ARHGAP5 0 0 120 177 1 1
SMAD4 RRAS2 129 0 0 211 1 1
SMAD4 CHORDC1 0 0 57 151 1 1
SMAD4 LIN28A 0 650 205 716 1 1
SMAD4 KLC2 0 0 297 308 1 1
SMAD4 TBX1 0 0 474 493 1 1
SMAD4 NEK6 128 0 457 507 1 1
SMAD4 PDPK1 0 0 181 381 1 2
SMAD4 DUSP6 0 0 145 178 1 1
SMAD4 MKL2 0 0 100 156 1 1
SMAD4 WNT10B 0 0 269 286 1 1
SMAD4 GFI1 0 0 134 156 1 1
SMAD4 CAT 0 0 207 207 1 2
SMAD4 DDX5 0 0 538 634 1 1
SMAD4 BARD1 0 0 324 335 1 1
SMAD4 DEK 0 0 55 177 1 1
SMAD4 MAGI2 0 0 99 237 1 1
SMAD4 HGF 0 0 456 464 1 2
SMAD4 STXBP3 0 0 0 213 1 1
SMAD4 SLC17A5 0 0 81 160 1 1
SMAD4 MCM7 0 0 134 164 1 1
SMAD4 POU5F1 0 600 558 830 1 2
SMAD4 NUMBL 0 0 113 151 1 1
SMAD4 ZFYVE9 0 650 928 980 1 1
SMAD4 RASA1 0 0 323 337 1 1
SMAD4 ADAMTS3 0 0 139 154 1 1
SMAD4 MECOM 270 0 181 425 1 1
SMAD4 BMPR2 0 650 893 975 1 1
SMAD4 TRIM62 0 0 134 161 1 1
SMAD4 SDHA 0 0 141 163 1 1
SMAD4 DCLK1 0 0 181 181 1 1
SMAD4 CASP8 0 0 314 313 1 2
SMAD4 REEP5 0 0 274 274 1 1
SMAD4 ITGB1 0 0 261 296 1 1
SMAD4 BCL9 0 0 210 210 1 1
SMAD4 CDK19 0 0 57 234 1 1
SMAD4 KAT2A 0 900 112 915 1 1
SMAD4 MFAP5 0 0 146 197 1 1
SMAD4 DSPP 0 0 370 370 1 1
SMAD4 HERC4 0 0 0 219 1 1
SMAD4 PIWIL4 0 0 166 172 1 1
SMAD4 NOTCH3 0 0 330 415 1 1
SMAD4 IL9 0 0 155 216 1 1
SMAD4 CSNK2A2 0 0 136 173 1 1
SMAD4 PBX2 0 0 74 255 1 1
SMAD4 FBLN1 130 0 96 197 1 1
SMAD4 CTNNA3 0 0 156 155 1 1
SMAD4 MYLK 0 0 232 231 1 1
SMAD4 PKNOX1 0 0 453 543 1 1
SMAD4 ZMIZ1 270 0 450 586 1 1
SMAD4 HIST1H4E 0 0 171 171 1 1
SMAD4 GLI2 270 0 340 510 1 2
SMAD4 NEUROG3 0 0 180 179 1 1
SMAD4 KMT2B 0 0 279 294 1 1
SMAD4 CDK6 0 0 457 467 1 2
SMAD4 PLG 131 0 373 445 1 1
SMAD4 LEFTY2 0 0 320 465 1 1
SMAD4 FZD8 0 0 181 247 1 1
SMAD4 ZEB2 0 0 630 642 1 1
SMAD4 FGF17 0 0 45 194 1 1
SMAD4 BMP7 0 0 681 793 1 1
SMAD4 TSC22D1 0 0 202 337 1 1
SMAD4 DLL3 0 0 134 152 1 1
SMAD4 BSG 0 0 450 462 1 1
SMAD4 LGALS4 0 0 379 396 1 1
SMAD4 RHOB 0 0 167 241 1 1
SMAD4 IL1A 0 0 228 227 1 1
SMAD4 CUX1 0 0 163 181 1 1
SMAD4 BMP10 0 0 459 528 1 1
SMAD4 DCTN1 0 0 669 670 1 1
SMAD4 TEAD3 0 0 115 203 1 1
SMAD4 FECH 0 0 450 450 1 1
SMAD4 SUZ12 0 0 183 268 1 1
SMAD4 ZNF215 0 0 57 156 1 1
SMAD4 TNS1 0 0 285 309 1 1
SMAD4 CDX1 0 0 195 224 1 1
SMAD4 KLF5 270 0 695 779 1 2
SMAD4 MED4 0 0 0 221 1 1
SMAD4 OTUB1 270 0 97 343 1 1
SMAD4 CLDN3 0 0 155 154 1 1
SMAD4 TFF1 0 0 194 204 1 1
SMAD4 PXN 0 0 241 252 1 1
SMAD4 HIST2H3PS2 0 0 391 405 1 1
SMAD4 NFIC 0 0 483 483 1 1
SMAD4 KRIT1 0 0 150 173 1 1
SMAD4 HES5 0 0 203 203 1 1
SMAD4 CTGF 0 0 611 665 1 1
SMAD4 SMARCB1 0 0 493 499 1 1
SMAD4 PRF1 0 0 155 154 1 1
SMAD4 NR3C1 0 900 241 925 1 1
SMAD4 FKBP1A 0 0 303 303 1 2
SMAD4 CISH 0 0 181 192 1 1
SMAD4 PDGFA 0 0 244 243 1 1
SMAD4 PMS1 0 0 391 390 1 1
SMAD4 SH3RF1 0 0 899 902 1 1
SMAD4 ADIPOQ 0 0 157 156 1 2
SMAD4 LTBP1 0 0 366 380 1 1
SMAD4 CAMTA1 0 0 142 180 1 1
SMAD4 FZD7 0 0 171 238 1 1
SMAD4 VIM 0 0 324 362 1 2
SMAD4 MEIS2 0 0 122 172 1 1
SMAD4 BTG3 0 0 97 266 1 1
SMAD4 SKP2 486 0 698 841 1 2
SMAD4 ARG1 0 0 158 157 1 2
SMAD4 AMOT 0 0 136 177 1 1
SMAD4 AURKB 0 0 143 154 1 1
SMAD4 FOXP1 0 600 213 725 1 1
SMAD4 MAGIX 0 0 0 174 1 1
SMAD4 TBX3 0 0 261 287 1 1
SMAD4 E4F1 0 0 241 270 1 1
SMAD4 RBPMS 0 0 354 354 1 1
SMAD4 ENO2 0 0 136 154 1 1
SMAD4 GDF2 0 0 652 703 1 1
SMAD4 NANOG 270 600 420 818 1 2
SMAD4 GULP1 0 0 67 166 1 1
SMAD4 CASP9 0 0 260 260 1 2
SMAD4 KLF13 0 0 134 156 1 1
SMAD4 SHOC2 0 0 95 212 1 1
SMAD4 MAPK9 0 800 334 864 1 2
SMAD4 NRP1 0 0 150 169 1 1
SMAD4 CHEK2 0 0 395 408 1 1
SMAD4 RPS6KA3 0 0 193 193 1 1
SMAD4 SLIT1 0 0 97 151 1 1
SMAD4 RGMA 0 0 150 286 1 1
SMAD4 SMARCA5 0 0 119 201 1 1
SMAD4 IL17A 0 0 310 309 1 2
SMAD4 OLFM4 0 0 138 157 1 1
SMAD4 EIF4A3 280 0 0 296 1 1
SMAD4 ETS1 0 0 513 530 1 1
SMAD4 STK16 0 0 351 351 1 1
SMAD4 ST6GALNAC5 0 0 46 190 1 1
SMAD4 LIF 0 0 243 242 1 2
SMAD4 COL5A1 0 0 241 397 1 1
SMAD4 ACVR1 0 0 796 870 1 1
SMAD4 RDX 0 0 101 160 1 1
SMAD4 CDKN1C 0 0 282 295 1 1
SMAD4 BPTF 0 0 84 321 1 1
SMAD4 TIE1 0 0 150 186 1 1
SMAD4 DAB2 0 0 289 288 1 1
SMAD4 NES 0 0 325 326 1 2
SMAD4 RPTOR 0 0 170 248 1 2
SMAD4 CEBPD 270 0 155 370 1 1
SMAD4 MYCL 0 0 203 203 1 1
SMAD4 ITGA1 0 0 150 185 1 1
SMAD4 GNAS 0 0 662 670 1 1
SMAD4 KPNB1 270 900 0 929 1 1
SMAD4 TNKS 0 0 135 187 1 1
SMAD4 DLL4 0 0 247 263 1 1
SMAD4 KPNA6 0 0 95 188 1 1
SMAD4 FSCN1 0 0 150 184 1 1
SMAD4 BCL2L11 0 900 395 936 1 2
SMAD4 MAPK12 0 0 134 184 1 1
SMAD4 MAML1 0 0 181 181 1 1
SMAD4 BRD3 0 0 87 189 1 1
SMAD4 SERPINA1 111 0 112 191 1 2
SMAD4 SEPHS1 0 0 43 357 1 1
SMAD4 NR2F2 270 0 712 787 1 1
SMAD4 ARID5A 0 0 0 159 1 1
SMAD4 HEPH 0 0 180 179 1 1
SMAD4 RGCC 0 0 319 319 1 1
SMAD4 UBE3C 0 0 0 196 1 1
SMAD4 DVL3 0 0 442 514 1 1
SMAD4 PLAT 0 0 151 166 1 1
SMAD4 CHEK1 128 0 251 318 1 2
SMAD4 DTX1 0 0 46 162 1 1
SMAD4 TMPRSS6 0 0 464 483 1 1
SMAD4 TLX2 0 0 134 235 1 1
SMAD4 SRF 0 0 283 345 1 1
SMAD4 TNFSF10 0 0 155 154 1 2
SMAD4 CAV1 161 0 342 424 1 2
SMAD4 MAP2K3 0 0 315 334 1 1
SMAD4 APPBP2 0 0 60 166 1 1
SMAD4 DLL1 0 0 267 283 1 1
SMAD4 ARID1B 0 0 293 322 1 1
SMAD4 FANCA 0 0 171 171 1 1
SMAD4 IGFBP3 0 0 210 210 1 2
SMAD4 CD8A 0 0 341 341 1 1
SMAD4 SAE1 0 0 142 171 1 1
SMAD4 LIMK2 0 0 101 223 1 1
SMAD4 RIPK2 128 0 0 194 1 2
SMAD4 ETV1 0 0 141 169 1 1
SMAD4 CRK 0 0 142 194 1 1
SMAD4 RBFOX1 0 0 156 155 1 1
SMAD4 TCF7 0 800 154 851 1 1
SMAD4 TOB1 270 0 511 674 1 1
SMAD4 ANGPT2 0 0 160 177 1 1
SMAD4 MMP2 0 0 639 645 1 2
SMAD4 ZBTB17 0 900 70 905 1 1
SMAD4 EI24 0 0 68 161 1 2
SMAD4 MSLN 0 0 293 293 1 1
SMAD4 ASCL2 0 0 194 194 1 1
SMAD4 TLE4 0 0 138 212 1 1
SMAD4 NKX2-2 0 0 125 198 1 1
SMAD4 TICAM1 0 0 0 206 1 2
SMAD4 SPOP 0 0 204 225 1 1
SMAD4 NCBP1 435 0 0 435 1 1
SMAD4 YWHAE 0 0 143 177 1 1
SMAD4 LCK 0 0 150 208 1 1
SMAD4 ATF7IP 161 0 57 185 1 1
SMAD4 MED12 0 0 279 299 1 1
SMAD4 FZD6 0 0 113 185 1 1
SMAD4 USP4 270 0 212 456 1 1
SMAD4 KRT15 0 0 149 168 1 1
SMAD4 CSNK1A1 0 0 181 226 1 1
SMAD4 SHH 0 0 563 601 1 2
SMAD4 MEX3B 128 0 695 726 1 1
SMAD4 DTX4 0 0 0 158 1 1
SMAD4 ESR2 213 0 210 370 1 1
SMAD4 LTBP2 0 0 218 235 1 1
SMAD4 RHOG 128 0 95 195 1 1
SMAD4 STK4 0 0 0 190 1 1
SMAD4 SEMA4A 0 0 155 154 1 1
SMAD4 PLA2G2D 0 0 357 357 1 1
SMAD4 USP6 0 0 53 210 1 1
SMAD4 FOXD3 0 0 193 275 1 1
SMAD4 PBX1 0 600 703 901 1 1
SMAD4 POU3F4 0 0 54 182 1 1
SMAD4 SIRT7 0 0 233 264 1 2
SMAD4 CD24 0 0 290 290 1 2
SMAD4 ZEB1 0 0 820 828 1 2
SMAD4 HSPA8 0 900 79 904 1 2
SMAD4 INSR 0 0 163 432 1 1
SMAD4 UBE2L3 213 0 70 250 1 1
SMAD4 ETV4 240 0 232 411 1 1
SMAD4 DAND5 0 0 181 205 1 1
SMAD4 EPCAM 0 0 468 468 1 2
SMAD4 GDF10 0 0 310 400 1 1
SMAD4 PARP1 0 600 193 670 1 2
SMAD4 RHOA 0 0 518 561 1 2
SMAD4 TCF7L1 0 800 209 863 1 1
SMAD4 NKRF 0 0 108 219 1 1
SMAD4 JUP 0 0 66 154 1 1
SMAD4 BCLAF1 0 0 123 179 1 1
SMAD4 SOX21 0 0 106 172 1 1
SMAD4 FGF4 0 0 242 321 1 1
SMAD4 CXCL12 0 0 334 334 1 2
SMAD4 RNF43 0 0 602 617 1 1
SMAD4 TPM1 0 0 182 181 1 1
SMAD4 PIWIL1 0 0 171 177 1 1
SMAD4 KLRK1 0 0 135 150 1 1
SMAD4 KDM1A 270 0 453 624 1 2
SMAD4 TLE1 0 900 125 916 1 1
SMAD4 WNT6 0 0 261 278 1 1
SMAD4 CD40 0 0 166 165 1 2
SMAD4 DNMT1 0 0 323 337 1 2
SMAD4 STUB1 462 0 357 639 1 2
SMAD4 HOXB1 0 0 96 153 1 1
SMAD4 FOXJ3 0 0 96 219 1 1
SMAD4 INS 0 0 459 475 1 2
SMAD4 ACTB 0 0 601 631 1 2
SMAD4 FOXG1 213 900 210 938 1 1
SMAD4 ADAMTS5 0 0 170 190 1 1
SMAD4 PBX3 0 0 52 217 1 1
SMAD4 SLC9A9 0 0 150 170 1 1
SMAD4 GLI3 213 0 336 469 1 1
SMAD4 HIST1H4J 0 0 170 169 1 1
SMAD4 PDGFD 0 0 170 169 1 1
SMAD4 F2RL2 0 0 0 181 1 1
SMAD4 B2M 0 0 241 240 1 1
SMAD4 PAX5 0 0 184 207 1 1
SMAD4 KEAP1 0 0 279 279 1 2
SMAD4 ROS1 0 0 334 548 1 1
SMAD4 SIRT3 0 0 181 261 1 2
SMAD4 PROM1 0 0 391 390 1 2
SMAD4 KMT2C 0 0 503 514 1 1
SMAD4 ANGPT1 0 0 193 209 1 1
SMAD4 INHBE 0 0 150 264 1 1
SMAD4 SP7 0 0 460 474 1 1
SMAD4 ANKRD2 0 0 326 337 1 1
SMAD4 HPGDS 0 0 586 586 1 1
SMAD4 FBXW7 0 0 666 666 1 2
SMAD4 SPAG9 0 0 466 486 1 1
SMAD4 FOSL1 0 0 261 277 1 1
SMAD4 PAX8 196 0 232 370 1 1
SMAD4 SETDB1 0 0 113 151 1 1
SMAD4 PDCD10 0 0 150 165 1 1
SMAD4 PKNOX2 0 0 0 173 1 1
SMAD4 PTCH2 0 0 142 172 1 1
SMAD4 PRSS1 0 0 376 385 1 1
SMAD4 NEUROD1 0 0 194 194 1 1
SMAD4 WRN 0 0 180 190 1 1
SMAD4 CEBPA 270 0 335 504 1 1
SMAD4 WNT7B 0 0 266 283 1 1
SMAD4 SMAD9 876 900 989 995 1 1
SMAD4 HIF1A 0 900 720 973 1 2
SMAD4 EDN1 0 0 323 323 1 1
SMAD4 SIRT5 0 0 166 203 1 1
SMAD4 SP1 875 900 371 991 1 2
SMAD4 CLINT1 0 0 0 157 1 1
SMAD4 ZMYM3 0 0 0 150 1 1
SMAD4 IL1B 0 0 414 414 1 2
SMAD4 FAT1 0 0 260 278 1 1
SMAD4 ID1 0 0 646 668 1 1
SMAD4 RNF11 270 0 837 882 1 1
SMAD4 MAPK13 72 0 81 166 1 1
SMAD4 LATS2 0 0 415 432 1 1
SMAD4 UBE2R2 0 0 0 170 1 1
SMAD4 ACVR1C 0 650 595 902 1 1
SMAD4 AFAP1 0 0 181 181 1 1
SMAD4 CCM2 0 0 158 157 1 1
SMAD4 CDK2 0 900 519 950 1 2
SMAD4 EPHA2 0 0 166 223 1 1
SMAD4 CDC73 0 0 166 187 1 1
SMAD4 SCN1A 0 0 0 175 1 1
SMAD4 CXCR2 0 0 204 217 1 1
SMAD4 HOXA11 0 0 118 197 1 1
SMAD4 ERBB2IP 270 0 141 441 1 1
SMAD4 ELK1 0 0 123 152 1 1
SMAD4 ZBTB14 0 0 123 177 1 1
SMAD4 PRKAR2B 0 0 74 200 1 1
SMAD4 HERC5 270 0 0 371 1 1
SMAD4 XPO1 0 0 487 570 1 1
SMAD4 DR1 0 0 45 192 1 1
SMAD4 TRAF4 0 0 157 167 1 1
SMAD4 ADAMTSL2 0 0 125 172 1 1
SMAD4 FGF13 0 0 325 376 1 1
SMAD4 NOTCH1 0 0 696 735 1 2
SMAD4 CCNC 0 900 92 907 1 1
SMAD4 ENSG00000278882 0 0 0 163 1 1
SMAD4 CBY1 0 0 58 220 1 1
SMAD4 PRMT1 0 0 113 227 1 1
SMAD4 LDLRAD4 0 0 139 208 1 1
SMAD4 TBR1 0 0 141 172 1 1
SMAD4 POTEF 0 0 207 268 1 1
SMAD4 KPNA1 0 0 95 175 1 1
SMAD4 SMO 0 0 0 241 1 1
SMAD4 BMP3 0 0 542 604 1 1
SMAD4 PPP1R12A 0 0 63 167 1 1
SMAD4 UCP2 0 0 102 175 1 2
SMAD4 PALB2 0 0 505 505 1 1
SMAD4 STARD6 0 0 81 245 1 1
SMAD4 CER1 0 0 137 187 1 1
SMAD4 CHMP2B 0 0 0 152 1 2
SMAD4 PRKG1 270 0 454 660 1 1
SMAD4 FRAT2 0 0 150 173 1 1
SMAD4 NALCN 0 0 134 195 1 1
SMAD4 IL6 0 0 517 520 1 2
SMAD4 TNFRSF19 0 0 81 153 1 1
SMAD4 CBX3 0 0 298 314 1 1
SMAD4 KCNA5 0 0 171 262 1 1
SMAD4 BRD2 0 0 90 188 1 1
SMAD4 H3F3A 0 0 125 201 1 1
SMAD4 LGR4 0 0 178 192 1 1
SMAD4 ACTR2 0 0 107 259 1 1
SMAD4 TNFRSF1A 0 0 205 205 1 1
SMAD4 SHMT1 272 0 0 272 1 1
SMAD4 MYOG 0 0 273 356 1 1
SMAD4 E2F6 0 0 182 199 1 1
SMAD4 TBX2 0 0 134 180 1 1
SMAD4 NOTCH4 270 0 265 452 1 1
SMAD4 MAPK4 0 0 134 342 1 1
SMAD4 IGFBP5 0 0 147 166 1 1
SMAD4 ARF1 0 0 73 154 1 1
SMAD4 POU3F2 0 0 86 157 1 1
SMAD4 C9orf3 180 0 44 203 1 1
SMAD4 SLC2A10 0 0 285 284 1 1
SMAD4 BIRC2 0 0 186 233 1 1
SMAD4 IFNG 0 0 218 271 1 2
SMAD4 AMER1 0 0 463 463 1 1
SMAD4 GAST 0 0 245 244 1 1
SMAD4 POLE 0 0 529 529 1 1
SMAD4 CCL5 0 0 181 181 1 2
SMAD4 TGFB3 0 900 681 971 1 1
SMAD4 STAG2 0 0 107 201 1 1
SMAD4 PCNP 0 0 0 233 1 1
SMAD4 TWSG1 0 0 456 504 1 1
SMAD4 ANXA5 0 0 334 375 1 2
SMAD4 WNT8A 0 0 235 253 1 1
SMAD4 CCNB1 0 0 266 296 1 1
SMAD4 FGF21 0 0 60 230 1 2
SMAD4 AKAP12 0 0 167 167 1 1
SMAD4 TAGLN 0 0 298 303 1 1
SMAD4 FOXM1 0 0 323 368 1 1
SMAD4 HES1 0 0 143 165 1 2
SMAD4 FBXO32 0 0 261 261 1 2
SMAD4 MGMT 0 0 286 286 1 2
SMAD4 CCDC68 0 0 134 221 1 1
SMAD4 KLF3 0 0 139 182 1 1
SMAD4 PHEX 0 0 134 282 1 1
SMAD4 U2AF1L4 0 0 167 167 1 1
SMAD4 PDP2 0 0 0 366 1 1
SMAD4 SIAH1 0 0 139 179 1 1
SMAD4 PLK1 0 0 211 228 1 2
SMAD4 EPO 0 0 261 261 1 2
SMAD4 COL11A2 0 0 52 194 1 1
SMAD4 KITLG 0 0 241 240 1 1
SMAD4 SOX3 0 0 154 179 1 1
SMAD4 RAN 0 0 82 164 1 2
SMAD4 TAB3 0 0 155 154 1 1
SMAD4 PHLPP1 0 0 228 306 1 2
SMAD4 DNMT3A 0 0 315 315 1 2
SMAD4 LAMC2 0 0 154 177 1 1
SMAD4 DNMT3B 0 0 241 240 1 1
SMAD4 MAPK8IP1 0 0 554 554 1 1
SMAD4 BCL2L1 0 0 391 390 1 2
SMAD4 TUBB4A 0 0 119 164 1 1
SMAD4 TLR4 0 0 461 471 1 2
SMAD4 SMAD2 998 900 990 999 1 2
SMAD4 OLIG1 0 0 139 158 1 1
SMAD4 ZFYVE16 0 900 893 991 1 1
SMAD4 ATRX 0 0 293 308 1 1
SMAD4 SNW1 271 650 193 789 1 1
SMAD4 JAG2 0 0 203 277 1 1
SMAD4 RGMB 0 0 211 265 1 1
SMAD4 CSMD1 0 0 161 175 1 1
SMAD4 HYAL2 270 0 695 808 1 1
SMAD4 NF1 0 0 822 826 1 1
SMAD4 ELF1 0 0 54 171 1 1
SMAD4 ZNF189 129 0 0 151 1 1
SMAD4 IL1R1 0 0 170 169 1 1
SMAD4 APEX1 0 0 137 160 1 1
SMAD4 GSC 0 0 123 295 1 1
SMAD4 MYC 0 900 783 978 1 2
SMAD4 NCSTN 0 0 90 294 1 1
SMAD4 PAX7 0 0 219 219 1 1
SMAD4 TMEFF2 0 0 118 209 1 1
SMAD4 IL18 0 0 173 173 1 2
SMAD4 HOXA9 270 0 938 971 1 1
SMAD4 USF1 0 0 161 161 1 1
SMAD4 TAB2 0 0 182 203 1 2
SMAD4 IGF1R 0 0 392 587 1 2
SMAD4 SDHC 0 0 458 472 1 1
SMAD4 COL11A1 0 0 155 306 1 1
SMAD4 SDHAF2 0 0 210 210 1 1
SMAD4 FGF10 0 0 324 366 1 1
SMAD4 UBE2D1 0 900 81 908 1 1
SMAD4 PI3 0 0 166 165 1 2
SMAD4 TAB1 0 0 269 315 1 1
SMAD4 NOG 0 0 654 666 1 1
SMAD4 MEN1 0 600 427 767 1 1
SMAD4 CTDSP1 0 0 95 196 1 1
SMAD4 SEMA6A 0 0 158 164 1 1
SMAD4 EVX1 0 0 67 158 1 1
SMAD4 MLH3 0 0 325 325 1 1
SMAD4 CERS1 0 0 193 297 1 1
SMAD4 PIK3CA 0 0 710 742 1 2
SMAD4 USP10 270 0 0 273 1 1
SMAD4 MMP17 0 0 47 211 1 1
SMAD4 HDAC3 0 0 96 161 1 2
SMAD4 HIST1H4L 0 0 170 169 1 1
SMAD4 SAMD8 0 0 0 314 1 1
SMAD4 MYCN 0 0 335 349 1 1
SMAD4 MEF2D 0 0 134 195 1 2
SMAD4 ZSCAN10 0 600 0 610 1 1
SMAD4 HDAC5 0 0 150 244 1 1
SMAD4 PARD3 270 0 71 292 1 1
SMAD4 NUPR1 0 0 155 158 1 2
SMAD4 FHL2 270 0 184 450 1 1
SMAD4 TFR2 0 0 500 520 1 1
SMAD4 NFE2L2 0 0 294 405 1 2
SMAD4 EHMT2 0 0 150 168 1 2
SMAD4 MECP2 0 0 164 182 1 1
SMAD4 CAB39 0 0 70 156 1 1
SMAD4 AKT2 0 0 349 559 1 2
SMAD4 GPR155 0 0 0 152 1 1
SMAD4 EML4 0 0 208 249 1 1
SMAD4 PLEKHA5 0 0 0 174 1 1
SMAD4 MNX1 0 0 112 168 1 1
SMAD4 UBE2K 0 0 127 199 1 1
SMAD4 ZNF423 486 0 949 973 1 1
SMAD4 FURIN 0 0 374 383 1 1
SMAD4 DSP 0 0 136 159 1 1
SMAD4 MAGI1 0 0 0 188 1 1
SMAD4 MAP2K1 0 0 506 548 1 1
SMAD4 EID1 0 0 308 307 1 1
SMAD4 PSCA 0 0 245 244 1 1
SMAD4 DHH 0 0 193 263 1 1
SMAD4 SGCG 0 0 66 201 1 1
SMAD4 PRKCI 0 0 134 202 1 1
SMAD4 CFTR 0 0 183 183 1 2
SMAD4 TRIM24 0 0 284 335 1 1
SMAD4 KPNA4 0 0 90 204 1 1
SMAD4 BNIP2 0 0 0 153 1 1
SMAD4 COL5A2 0 0 167 292 1 1
SMAD4 SARM1 0 0 315 320 1 1
SMAD4 FADD 0 0 202 216 1 2
SMAD4 UCHL5 0 0 134 211 1 1
SMAD4 DCUN1D1 0 0 156 164 1 1
SMAD4 CDK4 0 900 586 957 1 2
SMAD4 HIST1H4I 0 0 170 169 1 1
SMAD4 MYD88 0 0 228 258 1 2
SMAD4 PTPRD 0 0 231 247 1 1
SMAD4 CSF3 0 0 165 165 1 1
SMAD4 MUC5B 0 0 213 230 1 1
SMAD4 LMNA 0 0 235 270 1 2
SMAD4 PITX2 0 0 268 313 1 1
SMAD4 FGF7 0 0 260 310 1 1
SMAD4 SKOR1 0 0 135 258 1 1
SMAD4 SLMAP 0 0 0 192 1 1
SMAD4 DDIT3 0 0 140 157 1 2
SMAD4 KRT2 0 0 0 225 1 1
SMAD4 COL2A1 0 0 288 395 1 2
SMAD4 PAK1 128 0 113 225 1 2
SMAD4 WNT5B 0 0 285 409 1 1
SMAD4 ZNF48 0 0 94 158 1 1
SMAD4 CTBP2 0 0 125 176 1 1
SMAD4 FOXE3 0 0 193 247 1 1
SMAD4 AGR2 0 0 171 191 1 1
SMAD4 HGS 486 0 194 585 1 2
SMAD4 ZNF8 213 0 0 233 1 1
SMAD4 CYBRD1 0 0 218 218 1 1
SMAD4 ERN1 0 0 102 163 1 2
SMAD4 MTAP 0 0 181 181 1 1
SMAD4 NF2 0 0 363 363 1 1
SMAD4 NR2F1 0 0 170 194 1 1
SMAD4 GATA3 0 900 386 947 1 1
SMAD4 HOXD13 0 0 108 180 1 1
SMAD4 RBP2 0 0 309 309 1 1
SMAD4 TGFA 0 0 283 282 1 1
SMAD4 MKKS 0 0 202 207 1 1
SMAD4 AGO2 0 0 282 287 1 2
SMAD4 STAT3 0 0 752 759 1 2
SMAD4 DEAF1 0 0 196 353 1 1
SMAD4 ADAM9 0 0 103 159 1 1
SMAD4 EZH2 270 0 460 601 1 2
SMAD4 DKK2 0 0 241 240 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0003677 Molecular Function DNA binding contributes_to IDA
GO:0001228 Molecular Function DNA-binding transcription activator activity, RNA polymerase II-specific enables IDA
GO:0003700 Molecular Function DNA-binding transcription factor activity contributes_to IDA
GO:0003700 Molecular Function DNA-binding transcription factor activity enables IDA
GO:0000981 Molecular Function DNA-binding transcription factor activity, RNA polymerase II-specific enables IBA
GO:0000981 Molecular Function DNA-binding transcription factor activity, RNA polymerase II-specific enables ISA
GO:0070411 Molecular Function I-SMAD binding enables IBA
GO:0070411 Molecular Function I-SMAD binding enables IPI
GO:0070412 Molecular Function R-SMAD binding enables IPI
GO:0000978 Molecular Function RNA polymerase II cis-regulatory region sequence-specific DNA binding enables IBA
GO:0000978 Molecular Function RNA polymerase II cis-regulatory region sequence-specific DNA binding enables IDA
GO:0061629 Molecular Function RNA polymerase II-specific DNA-binding transcription factor binding enables IEA
GO:0003682 Molecular Function chromatin binding enables IEA
GO:0005518 Molecular Function collagen binding enables IEA
GO:0031005 Molecular Function filamin binding enables IEA
GO:0042802 Molecular Function identical protein binding enables IPI
GO:0046872 Molecular Function metal ion binding enables IEA
GO:0005515 Molecular Function protein binding enables IPI
GO:0042803 Molecular Function protein homodimerization activity enables IPI
GO:0044877 Molecular Function protein-containing complex binding enables IEA
GO:0043565 Molecular Function sequence-specific DNA binding enables IDA
GO:0043199 Molecular Function sulfate binding enables IMP
GO:0000976 Molecular Function transcription cis-regulatory region binding enables IDA
GO:0001223 Molecular Function transcription coactivator binding enables IPI
GO:0001222 Molecular Function transcription corepressor binding enables IPI
GO:0030509 Biological Process BMP signaling pathway involved_in IBA
GO:0030509 Biological Process BMP signaling pathway involved_in IDA
GO:0030509 Biological Process BMP signaling pathway involved_in IGI
GO:0030509 Biological Process BMP signaling pathway involved_in IMP
GO:0030509 Biological Process BMP signaling pathway involved_in ISS
GO:0006351 Biological Process DNA-templated transcription involved_in NAS
GO:0070371 Biological Process ERK1 and ERK2 cascade involved_in IEA
GO:0060395 Biological Process SMAD protein signal transduction involved_in IBA
GO:0060395 Biological Process SMAD protein signal transduction involved_in IDA
GO:0060395 Biological Process SMAD protein signal transduction involved_in IMP
GO:0060395 Biological Process SMAD protein signal transduction involved_in ISS
GO:0032924 Biological Process activin receptor signaling pathway involved_in NAS
GO:0030325 Biological Process adrenal gland development involved_in IEA
GO:0009653 Biological Process anatomical structure morphogenesis involved_in IBA
GO:0036302 Biological Process atrioventricular canal development involved_in ISS
GO:0003190 Biological Process atrioventricular valve formation involved_in ISS
GO:0007411 Biological Process axon guidance involved_in IEA
GO:0003360 Biological Process brainstem development involved_in IEA
GO:0001658 Biological Process branching involved in ureteric bud morphogenesis involved_in IEA
GO:0003161 Biological Process cardiac conduction system development involved_in NAS
GO:0014898 Biological Process cardiac muscle hypertrophy in response to stress involved_in IEA
GO:0030154 Biological Process cell differentiation involved_in IBA
GO:0071773 Biological Process cellular response to BMP stimulus involved_in NAS
GO:0071333 Biological Process cellular response to glucose stimulus involved_in IEA
GO:0071560 Biological Process cellular response to transforming growth factor beta stimulus involved_in IMP
GO:0048589 Biological Process developmental growth involved_in IEA
GO:0042733 Biological Process embryonic digit morphogenesis involved_in IEA
GO:0060956 Biological Process endocardial cell differentiation involved_in ISS
GO:0042118 Biological Process endothelial cell activation involved_in IEA
GO:0010631 Biological Process epithelial cell migration involved_in IMP
GO:0001837 Biological Process epithelial to mesenchymal transition involved_in IGI
GO:0001837 Biological Process epithelial to mesenchymal transition involved_in IMP
GO:0003198 Biological Process epithelial to mesenchymal transition involved in endocardial cushion formation involved_in IEA
GO:0097191 Biological Process extrinsic apoptotic signaling pathway involved_in IMP
GO:0061040 Biological Process female gonad morphogenesis involved_in IEA
GO:0048859 Biological Process formation of anatomical boundary involved_in IEA
GO:0001702 Biological Process gastrulation with mouth forming second involved_in IEA
GO:0001701 Biological Process in utero embryonic development involved_in IEA
GO:0070102 Biological Process interleukin-6-mediated signaling pathway involved_in ISS
GO:0006879 Biological Process intracellular iron ion homeostasis involved_in ISS
GO:0035556 Biological Process intracellular signal transduction involved_in IMP
GO:0003220 Biological Process left ventricular cardiac muscle tissue morphogenesis involved_in ISS
GO:0048382 Biological Process mesendoderm development involved_in IEA
GO:0072133 Biological Process metanephric mesenchyme morphogenesis involved_in IEA
GO:0045892 Biological Process negative regulation of DNA-templated transcription involved_in IDA
GO:0070373 Biological Process negative regulation of ERK1 and ERK2 cascade involved_in ISS
GO:0090090 Biological Process negative regulation of canonical Wnt signaling pathway acts_upstream_of_or_within IMP
GO:0010614 Biological Process negative regulation of cardiac muscle hypertrophy involved_in ISS
GO:1905305 Biological Process negative regulation of cardiac myofibril assembly involved_in ISS
GO:0030308 Biological Process negative regulation of cell growth involved_in IDA
GO:0008285 Biological Process negative regulation of cell population proliferation involved_in IEA
GO:0042177 Biological Process negative regulation of protein catabolic process involved_in IEA
GO:0000122 Biological Process negative regulation of transcription by RNA polymerase II involved_in ISS
GO:0072134 Biological Process nephrogenic mesenchyme morphogenesis involved_in IEA
GO:0014033 Biological Process neural crest cell differentiation involved_in IEA
GO:0048665 Biological Process neuron fate specification involved_in IMP
GO:0001649 Biological Process osteoblast differentiation involved_in IEA
GO:0003148 Biological Process outflow tract septum morphogenesis involved_in ISS
GO:0001541 Biological Process ovarian follicle development involved_in IEA
GO:0045893 Biological Process positive regulation of DNA-templated transcription involved_in IDA
GO:0060391 Biological Process positive regulation of SMAD protein signal transduction involved_in ISS
GO:0010666 Biological Process positive regulation of cardiac muscle cell apoptotic process involved_in IEA
GO:0003251 Biological Process positive regulation of cell proliferation involved in heart valve morphogenesis involved_in ISS
GO:0010718 Biological Process positive regulation of epithelial to mesenchymal transition involved_in ISS
GO:1901203 Biological Process positive regulation of extracellular matrix assembly involved_in IMP
GO:0046881 Biological Process positive regulation of follicle-stimulating hormone secretion involved_in IEA
GO:0010628 Biological Process positive regulation of gene expression involved_in IMP
GO:0033686 Biological Process positive regulation of luteinizing hormone secretion involved_in IEA
GO:1902895 Biological Process positive regulation of miRNA transcription involved_in IEA
GO:0045944 Biological Process positive regulation of transcription by RNA polymerase II involved_in IDA
GO:0045944 Biological Process positive regulation of transcription by RNA polymerase II involved_in ISS
GO:0045944 Biological Process positive regulation of transcription by RNA polymerase II involved_in TAS
GO:0030511 Biological Process positive regulation of transforming growth factor beta receptor signaling pathway involved_in IDA
GO:0051797 Biological Process regulation of hair follicle development involved_in IEA
GO:0006357 Biological Process regulation of transcription by RNA polymerase II involved_in IBA
GO:0017015 Biological Process regulation of transforming growth factor beta receptor signaling pathway involved_in IMP
GO:0032909 Biological Process regulation of transforming growth factor beta2 production involved_in IMP
GO:0001666 Biological Process response to hypoxia involved_in IMP
GO:0071559 Biological Process response to transforming growth factor beta involved_in IDA
GO:0048733 Biological Process sebaceous gland development involved_in IEA
GO:0062009 Biological Process secondary palate development involved_in ISS
GO:0072520 Biological Process seminiferous tubule development involved_in IEA
GO:0007338 Biological Process single fertilization involved_in IEA
GO:0032525 Biological Process somite rostral/caudal axis specification involved_in IEA
GO:0007283 Biological Process spermatogenesis involved_in IEA
GO:0006366 Biological Process transcription by RNA polymerase II involved_in IEA
GO:0007179 Biological Process transforming growth factor beta receptor signaling pathway involved_in IBA
GO:0007179 Biological Process transforming growth factor beta receptor signaling pathway involved_in IDA
GO:0007179 Biological Process transforming growth factor beta receptor signaling pathway involved_in IGI
GO:0007179 Biological Process transforming growth factor beta receptor signaling pathway involved_in IMP
GO:0007179 Biological Process transforming growth factor beta receptor signaling pathway involved_in ISS
GO:0060065 Biological Process uterus development involved_in IEA
GO:0060412 Biological Process ventricular septum morphogenesis involved_in ISS
GO:0071141 Cellular Component SMAD protein complex part_of IDA
GO:0071141 Cellular Component SMAD protein complex part_of IMP
GO:0032444 Cellular Component activin responsive factor complex part_of IDA
GO:0005813 Cellular Component centrosome located_in IDA
GO:0000785 Cellular Component chromatin part_of IDA
GO:0000785 Cellular Component chromatin part_of ISA
GO:0005737 Cellular Component cytoplasm located_in IDA
GO:0005829 Cellular Component cytosol located_in IDA
GO:0005829 Cellular Component cytosol located_in TAS
GO:0071144 Cellular Component heteromeric SMAD protein complex part_of IBA
GO:0071144 Cellular Component heteromeric SMAD protein complex part_of IPI
GO:0005654 Cellular Component nucleoplasm located_in IDA
GO:0005654 Cellular Component nucleoplasm located_in TAS
GO:0005634 Cellular Component nucleus located_in IDA
GO:0005667 Cellular Component transcription regulator complex part_of IDA
GO:0005667 Cellular Component transcription regulator complex part_of IPI
Pathways
Name DB ID
Signaling by NODAL Reactome R-HSA-1181150
Developmental Biology Reactome R-HSA-1266738
Signaling by Activin Reactome R-HSA-1502540
Signal Transduction Reactome R-HSA-162582
Disease Reactome R-HSA-1643685
Signaling by TGF-beta Receptor Complex Reactome R-HSA-170834
Signaling by BMP Reactome R-HSA-201451
Generic Transcription Pathway Reactome R-HSA-212436
TGF-beta receptor signaling activates SMADs Reactome R-HSA-2173789
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer Reactome R-HSA-2173793
Downregulation of SMAD2/3:SMAD4 transcriptional activity Reactome R-HSA-2173795
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Reactome R-HSA-2173796
Loss of Function of SMAD4 in Cancer Reactome R-HSA-3304347
Loss of Function of SMAD2/3 in Cancer Reactome R-HSA-3304349
Signaling by TGF-beta Receptor Complex in Cancer Reactome R-HSA-3304351
SMAD4 MH2 Domain Mutants in Cancer Reactome R-HSA-3311021
SMAD2/3 MH2 Domain Mutants in Cancer Reactome R-HSA-3315487
Metabolism of proteins Reactome R-HSA-392499
Transcriptional regulation of pluripotent stem cells Reactome R-HSA-452723
Diseases of signal transduction by growth factor receptors and second messengers Reactome R-HSA-5663202
Infectious disease Reactome R-HSA-5663205
Deubiquitination Reactome R-HSA-5688426
Ub-specific processing proteases Reactome R-HSA-5689880
Post-translational protein modification Reactome R-HSA-597592
RNA Polymerase II Transcription Reactome R-HSA-73857
Gene expression (Transcription) Reactome R-HSA-74160
Transcriptional regulation by RUNX3 Reactome R-HSA-8878159
Transcriptional regulation by RUNX2 Reactome R-HSA-8878166
RUNX2 regulates bone development Reactome R-HSA-8941326
RUNX3 regulates CDKN1A transcription Reactome R-HSA-8941855
RUNX3 regulates BCL2L11 (BIM) transcription Reactome R-HSA-8952158
Signaling by TGFB family members Reactome R-HSA-9006936
FOXO-mediated transcription Reactome R-HSA-9614085
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes Reactome R-HSA-9615017
FOXO-mediated transcription of cell cycle genes Reactome R-HSA-9617828
SARS-CoV-1 Infection Reactome R-HSA-9678108
SARS-CoV Infections Reactome R-HSA-9679506
SARS-CoV-1-host interactions Reactome R-HSA-9692914
SARS-CoV-1 targets host intracellular signalling and regulatory pathways Reactome R-HSA-9735871
Germ layer formation at gastrulation Reactome R-HSA-9754189
Gastrulation Reactome R-HSA-9758941
Formation of definitive endoderm Reactome R-HSA-9823730
Viral Infection Pathways Reactome R-HSA-9824446
Neuroinflammation and glutamatergic signaling (WP5083) WikiPathways WP5083_r120385
Hypothesized pathways in pathogenesis of cardiovascular disease (WP3668) WikiPathways WP3668_r123393
BMP signaling in eyelid development (WP3927) WikiPathways WP3927_r123370
Canonical and non-canonical TGF-B signaling (WP3874) WikiPathways WP3874_r116461
TGF-beta signaling pathway (WP366) WikiPathways WP366_r120697
TGF-beta receptor signaling in skeletal dysplasias (WP4816) WikiPathways WP4816_r116440
Hair follicle development: cytodifferentiation - part 3 of 3 (WP2840) WikiPathways WP2840_r120866
Chromosomal and microsatellite instability in colorectal cancer (WP4216) WikiPathways WP4216_r123363
Hepatitis B infection (WP4666) WikiPathways WP4666_r123495
Endoderm differentiation (WP2853) WikiPathways WP2853_r116557
Extracellular vesicle-mediated signaling in recipient cells (WP2870) WikiPathways WP2870_r106411
Cell cycle (WP179) WikiPathways WP179_r122978
Osteoblast differentiation and related diseases (WP4787) WikiPathways WP4787_r118872
Mesodermal commitment pathway (WP2857) WikiPathways WP2857_r118395
Angiotensin II receptor type 1 pathway (WP5036) WikiPathways WP5036_r119016
Epithelial to mesenchymal transition in colorectal cancer (WP4239) WikiPathways WP4239_r118997
Clock-controlled autophagy in bone metabolism (WP5205) WikiPathways WP5205_r122560
TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition (WP3859) WikiPathways WP3859_r117840
Androgen receptor signaling pathway (WP138) WikiPathways WP138_r122133
DNA damage response (only ATM dependent) (WP710) WikiPathways WP710_r116542
Progeria-associated lipodystrophy (WP5103) WikiPathways WP5103_r119170
TGF-beta receptor signaling (WP560) WikiPathways WP560_r117838
Envelope proteins and their potential roles in EDMD physiopathology (WP4535) WikiPathways WP4535_r109210
Heart development (WP1591) WikiPathways WP1591_r118366
Ectoderm differentiation (WP2858) WikiPathways WP2858_r116763
Hematopoietic stem cell gene regulation by GABP alpha/beta complex (WP3657) WikiPathways WP3657_r123358
NRP1-triggered signaling pathways in pancreatic cancer (WP5144) WikiPathways WP5144_r120537
Hepatitis C and hepatocellular carcinoma (WP3646) WikiPathways WP3646_r116732
Pancreatic adenocarcinoma pathway (WP4263) WikiPathways WP4263_r123405
Head and neck squamous cell carcinoma (WP4674) WikiPathways WP4674_r123494
Vitamin D in inflammatory diseases (WP4482) WikiPathways WP4482_r121703
Bone morphogenic protein signaling and regulation (WP1425) WikiPathways WP1425_r123619
Regucalcin in proximal tubule epithelial kidney cells (WP4838) WikiPathways WP4838_r110282
Embryonic stem cell pluripotency pathways (WP3931) WikiPathways WP3931_r117717
Transcripts
Accession Version MolecularType Name NCBI Comments
NR_176265 1 miscRNA transcript variant 6 NC_000018 Reference
NR_176264 1 miscRNA transcript variant 5 NC_000018 Reference
NM_005359 6 mRNA transcript variant 1 NC_000018 Reference
NM_001407042 1 mRNA transcript variant 3 NC_000018 Reference
NM_001407041 1 mRNA transcript variant 2 NC_000018 Reference
NM_001407043 1 mRNA transcript variant 4 NC_000018 Reference