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MAX

MYC associated factor X
General Information
Name MYC associated factor X
Alias
  • protein max
  • class D basic helix-loop-helix protein 4
Gene_family Basic helix-loop-helix proteins
organism Homo sapiens
entrez_id 4149
location 14q23.3
transcript_count 41
exon_count 10
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
    Stringdb Protein max; Transcription regulator. Forms a sequence-specific DNA- binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity. Represses MYC transcriptional activity from E-box elements
    nextProt Transcription regulator. Forms a sequence-specific DNA-binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC:MAX complex is a transcriptional activator, whereas the MAD:MAX complex is a repressor. May repress transcription via the recruitment of a chromatin remodeling complex containing H3 'Lys-9' histone methyltransferase activity. Represses MYC transcriptional activity from E-box elements.
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
MAX BioGRID ORF1ab GeneID BioGRID Proximity Label-MS
MAX BioGRID MYC GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-crystal Structure; Co-fractionation; FRET; Proximity Label-MS; Reconstituted Complex; Two-hybrid
MAX BioGRID USP1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-localization; Reconstituted Complex
MAX BioGRID RAD21 GeneID BioGRID Affinity Capture-MS
MAX BioGRID H3-3A GeneID BioGRID Proximity Label-MS
MAX BioGRID RNF2 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
MAX BioGRID ZRANB1 GeneID BioGRID Affinity Capture-MS
MAX BioGRID LATS1 GeneID BioGRID Affinity Capture-MS
MAX BioGRID KIF3A GeneID BioGRID Co-fractionation
MAX BioGRID WDR5 GeneID BioGRID Affinity Capture-MS; Co-fractionation
MAX BioGRID EHMT2 GeneID BioGRID Co-fractionation
MAX BioGRID RUVBL2 GeneID BioGRID Affinity Capture-MS; Co-fractionation
MAX BioGRID THRAP3 GeneID BioGRID Co-fractionation
MAX BioGRID RUVBL1 GeneID BioGRID Affinity Capture-MS; Co-fractionation
MAX BioGRID XRCC5 GeneID BioGRID Co-fractionation
MAX BioGRID HADHA GeneID BioGRID Co-fractionation
MAX BioGRID XRCC6 GeneID BioGRID Co-fractionation
MAX BioGRID DAXX GeneID BioGRID Co-fractionation
MAX BioGRID CDH1 GeneID BioGRID Negative Genetic
MAX BioGRID PARP1 GeneID BioGRID Co-fractionation
MAX BioGRID RING1 GeneID BioGRID Affinity Capture-MS; Co-fractionation
MAX BioGRID RBBP5 GeneID BioGRID Co-fractionation
MAX BioGRID PRKDC GeneID BioGRID Co-fractionation
MAX BioGRID POLR2H GeneID BioGRID Co-fractionation
MAX BioGRID NPM1 GeneID BioGRID Co-fractionation
MAX BioGRID KPNB1 GeneID BioGRID Co-fractionation
MAX BioGRID JUP GeneID BioGRID Co-fractionation
MAX BioGRID HCFC1 GeneID BioGRID Co-fractionation
MAX BioGRID EHMT1 GeneID BioGRID Co-fractionation
MAX BioGRID CHD8 GeneID BioGRID Co-fractionation
MAX BioGRID PELP1 GeneID BioGRID Co-fractionation
MAX BioGRID PRPF31 GeneID BioGRID Co-fractionation
MAX BioGRID MGA GeneID BioGRID Affinity Capture-MS; Co-fractionation; Two-hybrid
MAX BioGRID TOP1 GeneID BioGRID Co-fractionation
MAX BioGRID TCOF1 GeneID BioGRID Co-fractionation
MAX BioGRID TAF7 GeneID BioGRID Co-fractionation
MAX BioGRID TAF6 GeneID BioGRID Co-fractionation
MAX BioGRID MYCN GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-purification; PCA; Reconstituted Complex
MAX BioGRID EZH2 GeneID BioGRID Affinity Capture-Western
MAX BioGRID FOXC1 GeneID BioGRID Affinity Capture-MS
MAX BioGRID TRRAP GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-purification
MAX BioGRID KRAS GeneID BioGRID Negative Genetic
MAX BioGRID EGFR GeneID BioGRID Negative Genetic
MAX BioGRID CSNK2A1 GeneID BioGRID Affinity Capture-MS; Biochemical Activity
MAX BioGRID SP7 GeneID BioGRID Proximity Label-MS
MAX BioGRID KLF16 GeneID BioGRID Proximity Label-MS
MAX BioGRID FEV GeneID BioGRID Proximity Label-MS
MAX BioGRID KLF8 GeneID BioGRID Proximity Label-MS
MAX BioGRID KLF9 GeneID BioGRID Proximity Label-MS
MAX BioGRID MXD1 GeneID BioGRID Affinity Capture-Luminescence; Affinity Capture-MS; Affinity Capture-Western; Co-crystal Structure; Co-purification; Reconstituted Complex; Two-hybrid
MAX BioGRID HSPB2 GeneID BioGRID Affinity Capture-MS
MAX BioGRID E2F6 GeneID BioGRID Affinity Capture-MS
MAX BioGRID AGRN GeneID BioGRID Affinity Capture-MS
MAX BioGRID TXLNB GeneID BioGRID Affinity Capture-MS
MAX BioGRID WBP2NL GeneID BioGRID Affinity Capture-MS
MAX BioGRID FOXR2 GeneID BioGRID Affinity Capture-MS
MAX BioGRID BRMS1L GeneID BioGRID Affinity Capture-MS
MAX BioGRID PCGF6 GeneID BioGRID Affinity Capture-MS
MAX BioGRID L3MBTL2 GeneID BioGRID Affinity Capture-MS
MAX BioGRID MXD3 GeneID BioGRID Affinity Capture-MS; Reconstituted Complex; Two-hybrid
MAX BioGRID REXO5 GeneID BioGRID Affinity Capture-MS
MAX BioGRID EPC1 GeneID BioGRID Affinity Capture-MS
MAX BioGRID PIP4K2C GeneID BioGRID Affinity Capture-MS
MAX BioGRID SAP130 GeneID BioGRID Affinity Capture-MS
MAX BioGRID SUDS3 GeneID BioGRID Affinity Capture-MS
MAX BioGRID EP400 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-purification
MAX BioGRID BRMS1 GeneID BioGRID Affinity Capture-MS
MAX BioGRID RYBP GeneID BioGRID Affinity Capture-MS
MAX BioGRID MXD4 GeneID BioGRID Affinity Capture-MS; Reconstituted Complex; Two-hybrid
MAX BioGRID KAT5 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
MAX BioGRID YAF2 GeneID BioGRID Affinity Capture-MS
MAX BioGRID MBTD1 GeneID BioGRID Affinity Capture-MS
MAX BioGRID ING3 GeneID BioGRID Affinity Capture-MS
MAX BioGRID ARID4B GeneID BioGRID Affinity Capture-MS
MAX BioGRID HSD17B14 GeneID BioGRID Affinity Capture-MS
MAX BioGRID EPC2 GeneID BioGRID Affinity Capture-MS
MAX BioGRID SIN3A GeneID BioGRID Affinity Capture-MS
MAX BioGRID VPS72 GeneID BioGRID Affinity Capture-MS
MAX BioGRID PIP4K2A GeneID BioGRID Affinity Capture-MS
MAX BioGRID CHMP1A GeneID BioGRID Affinity Capture-MS
MAX BioGRID MXI1 GeneID BioGRID Affinity Capture-Luminescence; Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex; Two-hybrid
MAX BioGRID MNT GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex; Two-hybrid
MAX BioGRID SAP30 GeneID BioGRID Affinity Capture-MS
MAX BioGRID BFSP2 GeneID BioGRID Affinity Capture-MS
MAX BioGRID PIP4K2B GeneID BioGRID Affinity Capture-MS
MAX BioGRID CCDC6 GeneID BioGRID Affinity Capture-MS
MAX BioGRID TFDP1 GeneID BioGRID Affinity Capture-MS
MAX BioGRID ZNHIT3 GeneID BioGRID Affinity Capture-Western
MAX BioGRID TULP3 GeneID BioGRID Affinity Capture-MS
MAX BioGRID GLOD4 GeneID BioGRID Affinity Capture-MS
MAX BioGRID SND1 GeneID BioGRID Affinity Capture-MS
MAX BioGRID CBX3 GeneID BioGRID Affinity Capture-MS
MAX BioGRID CBX1 GeneID BioGRID Affinity Capture-MS
MAX BioGRID ACLY GeneID BioGRID Affinity Capture-MS
MAX BioGRID TFDP2 GeneID BioGRID Affinity Capture-MS
MAX BioGRID WDR76 GeneID BioGRID Affinity Capture-MS; Co-purification
MAX BioGRID MCF2L2 GeneID BioGRID Affinity Capture-MS
MAX BioGRID BRD8 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
MAX BioGRID FARP2 GeneID BioGRID Affinity Capture-MS
MAX BioGRID LDLR GeneID BioGRID Positive Genetic
MAX BioGRID HNRNPH1 GeneID BioGRID Affinity Capture-RNA
MAX BioGRID PLEKHF2 GeneID BioGRID Two-hybrid
MAX BioGRID H4C1 GeneID BioGRID Affinity Capture-MS
MAX BioGRID SPDL1 GeneID BioGRID Affinity Capture-MS
MAX BioGRID HIRA GeneID BioGRID Co-localization
MAX BioGRID SPRR1B GeneID BioGRID Affinity Capture-MS
MAX BioGRID SKP1 GeneID BioGRID Affinity Capture-MS
MAX BioGRID UBN1 GeneID BioGRID Co-localization
MAX BioGRID ASF1A GeneID BioGRID Co-localization
MAX BioGRID FBXW11 GeneID BioGRID Affinity Capture-MS
MAX BioGRID MYCL GeneID BioGRID Affinity Capture-MS; Reconstituted Complex
MAX BioGRID HDAC2 GeneID BioGRID Affinity Capture-MS
MAX BioGRID ARG1 GeneID BioGRID Affinity Capture-MS
MAX BioGRID MTOR GeneID BioGRID Negative Genetic
MAX BioGRID LEO1 GeneID BioGRID Negative Genetic
MAX BioGRID MRPL36 GeneID BioGRID Negative Genetic
MAX BioGRID MED9 GeneID BioGRID Positive Genetic
MAX BioGRID CDK12 GeneID BioGRID Positive Genetic
MAX BioGRID MBTPS2 GeneID BioGRID Negative Genetic
MAX BioGRID CNOT1 GeneID BioGRID Positive Genetic
MAX BioGRID METAP2 GeneID BioGRID Positive Genetic
MAX BioGRID PPIE GeneID BioGRID Positive Genetic
MAX BioGRID PSMD6 GeneID BioGRID Positive Genetic
MAX BioGRID SSBP1 GeneID BioGRID Negative Genetic
MAX BioGRID SDHC GeneID BioGRID Positive Genetic
MAX BioGRID PSPH GeneID BioGRID Positive Genetic
MAX BioGRID NDUFB2 GeneID BioGRID Negative Genetic
MAX BioGRID NDUFA8 GeneID BioGRID Negative Genetic
MAX BioGRID MAX GeneID BioGRID Affinity Capture-Western; Co-crystal Structure; Negative Genetic; Reconstituted Complex
MAX BioGRID MEAF6 GeneID BioGRID Affinity Capture-MS
MAX BioGRID DMAP1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
MAX BioGRID MORF4L1 GeneID BioGRID Affinity Capture-MS
MAX BioGRID MORF4L2 GeneID BioGRID Affinity Capture-MS
MAX BioGRID YEATS4 GeneID BioGRID Affinity Capture-MS
MAX BioGRID PPP2R1B GeneID BioGRID Affinity Capture-MS
MAX BioGRID PPP2R1A GeneID BioGRID Affinity Capture-MS
MAX BioGRID PPP2CB GeneID BioGRID Affinity Capture-MS
MAX BioGRID PPP2CA GeneID BioGRID Affinity Capture-MS
MAX BioGRID MRGBP GeneID BioGRID Affinity Capture-MS
MAX BioGRID ACTL6B GeneID BioGRID Affinity Capture-MS
MAX BioGRID ACTL6A GeneID BioGRID Affinity Capture-MS
MAX BioGRID TRIM25 GeneID BioGRID Affinity Capture-RNA
MAX BioGRID BMAL1 GeneID BioGRID Affinity Capture-MS
MAX BioGRID PHLDB3 GeneID BioGRID Affinity Capture-MS
MAX BioGRID CAVIN1 GeneID BioGRID Affinity Capture-MS
MAX BioGRID NUF2 GeneID BioGRID Affinity Capture-MS
MAX BioGRID NCKAP5L GeneID BioGRID Affinity Capture-MS
MAX BioGRID THAP11 GeneID BioGRID Affinity Capture-MS
MAX BioGRID GRIPAP1 GeneID BioGRID Affinity Capture-MS
MAX BioGRID VPS50 GeneID BioGRID Affinity Capture-MS
MAX BioGRID VPS53 GeneID BioGRID Affinity Capture-MS
MAX BioGRID RPRD1A GeneID BioGRID Affinity Capture-MS
MAX BioGRID HAUS6 GeneID BioGRID Affinity Capture-MS
MAX BioGRID CCHCR1 GeneID BioGRID Affinity Capture-MS
MAX BioGRID CCDC93 GeneID BioGRID Affinity Capture-MS
MAX BioGRID PHF21A GeneID BioGRID Affinity Capture-MS
MAX BioGRID PKN3 GeneID BioGRID Affinity Capture-MS
MAX BioGRID TFPT GeneID BioGRID Affinity Capture-MS
MAX BioGRID RABGEF1 GeneID BioGRID Affinity Capture-MS
MAX BioGRID RCOR1 GeneID BioGRID Affinity Capture-MS
MAX BioGRID KDM1A GeneID BioGRID Affinity Capture-MS
MAX BioGRID OIP5 GeneID BioGRID Affinity Capture-MS
MAX BioGRID HMG20A GeneID BioGRID Affinity Capture-MS
MAX BioGRID GOLGA5 GeneID BioGRID Affinity Capture-MS
MAX BioGRID RABGAP1L GeneID BioGRID Affinity Capture-MS
MAX BioGRID GIT2 GeneID BioGRID Affinity Capture-MS
MAX BioGRID DZIP3 GeneID BioGRID Affinity Capture-MS
MAX BioGRID CLOCK GeneID BioGRID Affinity Capture-MS
MAX BioGRID TUFT1 GeneID BioGRID Affinity Capture-MS
MAX BioGRID PSMD9 GeneID BioGRID Affinity Capture-MS
MAX BioGRID JUN GeneID BioGRID Affinity Capture-MS
MAX BioGRID TCP10L GeneID BioGRID Affinity Capture-MS
MAX BioGRID POU5F1 GeneID BioGRID Affinity Capture-MS
MAX BioGRID DNMT3L GeneID BioGRID Affinity Capture-Western; Co-localization; Reconstituted Complex
MAX BioGRID FOXR1 GeneID BioGRID Affinity Capture-MS
MAX BioGRID FBXW7 GeneID BioGRID Affinity Capture-MS
MAX BioGRID MTERF1 GeneID BioGRID Affinity Capture-MS
MAX BioGRID XRCC1 GeneID BioGRID Affinity Capture-MS
MAX BioGRID TWIST1 GeneID BioGRID Affinity Capture-MS
MAX BioGRID TFAP2A GeneID BioGRID Affinity Capture-MS
MAX BioGRID TBP GeneID BioGRID Affinity Capture-MS
MAX BioGRID SMARCA1 GeneID BioGRID Affinity Capture-MS
MAX BioGRID RPA2 GeneID BioGRID Affinity Capture-MS
MAX BioGRID RECQL GeneID BioGRID Affinity Capture-MS
MAX BioGRID MSH2 GeneID BioGRID Affinity Capture-Western; Co-localization; Reconstituted Complex
MAX BioGRID MECP2 GeneID BioGRID Affinity Capture-MS
MAX BioGRID SMAD3 GeneID BioGRID Co-localization; Reconstituted Complex
MAX BioGRID LIG3 GeneID BioGRID Affinity Capture-MS
MAX BioGRID FOXK2 GeneID BioGRID Affinity Capture-MS
MAX BioGRID EEF1D GeneID BioGRID Affinity Capture-MS
MAX BioGRID MAPK14 GeneID BioGRID Co-localization
MAX BioGRID FOXK1 GeneID BioGRID Affinity Capture-MS
MAX BioGRID WIZ GeneID BioGRID Affinity Capture-MS
MAX BioGRID VRK3 GeneID BioGRID Affinity Capture-MS
MAX BioGRID MORC2 GeneID BioGRID Affinity Capture-MS
MAX BioGRID BAZ1A GeneID BioGRID Affinity Capture-MS
MAX BioGRID MACROH2A1 GeneID BioGRID Affinity Capture-MS
MAX BioGRID SMARCA5 GeneID BioGRID Affinity Capture-MS
MAX BioGRID KDM5C GeneID BioGRID Affinity Capture-MS
MAX BioGRID XPO1 GeneID BioGRID Affinity Capture-MS
MAX BioGRID USP37 GeneID BioGRID Affinity Capture-Western
MAX BioGRID UNC45A GeneID BioGRID Two-hybrid
MAX BioGRID BANP GeneID BioGRID Two-hybrid
MAX BioGRID RPL35 GeneID BioGRID Reconstituted Complex
MAX BioGRID TUBA1A GeneID BioGRID Reconstituted Complex
MAX BioGRID RPL34 GeneID BioGRID Reconstituted Complex
MAX BioGRID GABBR1 GeneID BioGRID Reconstituted Complex
MAX BioGRID FUS GeneID BioGRID Reconstituted Complex
MAX BioGRID FTH1 GeneID BioGRID Reconstituted Complex
MAX BioGRID PLIN3 GeneID BioGRID Two-hybrid
MAX BioGRID HSP90AA1 GeneID BioGRID Affinity Capture-Luminescence
MAX BioGRID CPSF6 GeneID BioGRID Co-fractionation
MAX BioGRID ARL6IP5 GeneID BioGRID Co-fractionation
MAX BioGRID KMT2D GeneID BioGRID Co-fractionation
MAX BioGRID HNRNPH2 GeneID BioGRID Co-fractionation
MAX BioGRID DYNC1H1 GeneID BioGRID Co-fractionation
MAX BioGRID CSTF2 GeneID BioGRID Co-fractionation
MAX BioGRID SNIP1 GeneID BioGRID Two-hybrid
MAX BioGRID PPP1CC GeneID BioGRID Affinity Capture-Western
MAX BioGRID PPP1CB GeneID BioGRID Affinity Capture-Western
MAX BioGRID PPP1CA GeneID BioGRID Affinity Capture-Western
MAX BioGRID USF1 GeneID BioGRID Affinity Capture-MS
MAX BioGRID HSPA1A GeneID BioGRID Affinity Capture-MS
MAX BioGRID PIM1 GeneID BioGRID Affinity Capture-Western
MAX BioGRID HIF1A GeneID BioGRID Affinity Capture-Western
MAX BioGRID EPAS1 GeneID BioGRID Affinity Capture-Western
MAX BioGRID CCNT1 GeneID BioGRID Affinity Capture-Western
MAX BioGRID EP300 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
MAX BioGRID YY1 GeneID BioGRID Affinity Capture-Western
MAX BioGRID HNRNPU GeneID BioGRID Affinity Capture-Western
MAX BioGRID CEBPA GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
MAX BioGRID TXLNG GeneID BioGRID Two-hybrid
MAX BioGRID PLEKHA5 GeneID BioGRID Two-hybrid
MAX BioGRID COPS5 GeneID BioGRID Two-hybrid
MAX BioGRID CLIP2 GeneID BioGRID Two-hybrid
MAX BioGRID TAF1 GeneID BioGRID Two-hybrid
MAX BioGRID CUX1 GeneID BioGRID Two-hybrid
MAX Protein PLEKHF2 GeneID HPRD
MAX Protein MXD3 GeneID HPRD
MAX Protein SPAG9 GeneID HPRD
MAX Protein MXD4 GeneID HPRD
MAX Protein SNIP1 GeneID HPRD
MAX Protein EPAS1 GeneID HPRD
MAX Protein HIF1A GeneID HPRD
MAX Protein SMAD3 GeneID HPRD
MAX Protein MNT GeneID HPRD
MAX Protein TRRAP GeneID HPRD
MAX Protein MAD1L1 GeneID HPRD
MAX Protein CASP5 GeneID HPRD
MAX Protein CASP7 GeneID HPRD
MAX Protein SMAD4 GeneID HPRD
MAX Protein MAPK14 GeneID HPRD
MAX Protein MXD1 GeneID HPRD
MAX Protein MXI1 GeneID HPRD
MAX Protein L-myc-2 protein None HPRD
MAX Protein MYC GeneID HPRD
MAX Protein TEAD1 GeneID HPRD
MAX Protein MYCL GeneID HPRD
MAX Protein MYCN GeneID HPRD
MAX Protein MAX GeneID HPRD
MAX Protein MSH2 GeneID HPRD
MAX Protein CSNK2A1 GeneID HPRD
MAX BioGRID SPAG9 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
MAX BioGRID ZBTB17 GeneID BioGRID Reconstituted Complex
MAX BioGRID TEAD1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
MAX BioGRID SMAD4 GeneID BioGRID Reconstituted Complex
MAX BioGRID KAT2A GeneID BioGRID Affinity Capture-Western
MAX Protein MYC GeneID BIND Myc interacts with Max. This interaction was modeled on a demonstrated interaction between human Myc and Max from an unspecified source.
MAX Protein MSH2 GeneID BIND Max interacts with MSH2. This is a modeled interaction between Max from an unspecified source and human MSH2.
MAX Protein MXD1 GeneID BIND Max interacts with Mad1.
MAX Protein MXI1 GeneID BIND Max interacts with Mxi1.
StringDB
A B experiments database textmining combined score hadb nhadb
MAX TRRAP 835 900 369 989 1 1
MAX TMEM41B 0 0 52 175 1 1
MAX TAF5L 270 0 0 275 1 1
MAX HAP1 0 0 71 157 1 1
MAX CDKN1B 0 0 190 334 1 2
MAX GTF2B 0 0 52 221 1 1
MAX BOLA2-SMG1P6 0 0 0 161 1 1
MAX CTCF 0 0 180 376 1 1
MAX TBX4 0 0 60 153 1 1
MAX TCHP 0 0 193 193 1 1
MAX BIN1 0 0 104 162 1 1
MAX DNMT3L 270 0 0 270 1 1
MAX FOXP3 0 0 0 181 1 2
MAX MDH2 0 0 325 325 1 1
MAX MITF 0 0 66 579 1 2
MAX RNF2 545 900 60 962 1 1
MAX YY1 270 0 242 452 1 1
MAX ADSSL1 0 0 108 163 1 1
MAX RPL11 0 900 120 909 1 1
MAX ELK4 0 0 281 296 1 1
MAX FBXW11 267 0 0 319 1 1
MAX VHL 0 0 144 168 1 2
MAX MCRS1 0 900 0 900 1 1
MAX FBXW9 0 0 0 181 1 1
MAX CDKN3 0 0 140 171 1 1
MAX RABGEF1 128 0 0 171 1 1
MAX TAF4 0 900 0 903 1 1
MAX TCF12 0 0 135 321 1 1
MAX THOC5 0 0 119 226 1 1
MAX KDM6A 0 0 0 183 1 1
MAX FOXO3 0 0 140 215 1 2
MAX C17orf49 0 900 0 900 1 1
MAX SIN3B 0 900 139 928 1 1
MAX ACTL6A 270 900 74 934 1 1
MAX STAMBP 0 0 73 259 1 1
MAX IRF8 0 900 0 900 1 1
MAX DUX4L7 0 0 0 160 1 1
MAX CHTF18 0 0 0 157 1 1
MAX CTCFL 0 0 97 210 1 1
MAX CCNE2 0 650 0 652 1 1
MAX NHLH2 0 0 0 440 1 1
MAX TH 0 0 159 158 1 2
MAX OIP5 128 0 0 165 1 1
MAX ATOH1 0 0 0 157 1 1
MAX RAP1GDS1 0 0 102 496 1 1
MAX SUPT3H 270 900 0 925 1 1
MAX PHF20 0 900 0 902 1 1
MAX RBBP5 0 900 0 904 1 1
MAX HSP90AB1 129 0 0 163 1 2
MAX DUX4L4 0 0 0 160 1 1
MAX BRDT 0 0 60 152 1 1
MAX KMT2D 271 0 63 315 1 1
MAX SDHD 0 0 611 613 1 1
MAX HMGN2 0 0 183 183 1 1
MAX E2F4 0 0 194 220 1 1
MAX ARF4 0 0 61 158 1 1
MAX GTF2A1 0 0 124 152 1 1
MAX AKT1 0 0 211 231 1 2
MAX SLC16A7 0 0 0 151 1 1
MAX MXD1 988 900 637 999 1 1
MAX SUN3 0 0 45 164 1 1
MAX FOXA1 0 0 113 181 1 1
MAX ABI2 0 0 0 150 1 1
MAX LAS1L 0 900 0 900 1 1
MAX ERCC3 0 0 0 210 1 1
MAX LEO1 43 0 0 181 1 1
MAX FOXR1 231 0 0 243 1 1
MAX SDHAF1 0 0 173 173 1 1
MAX PAX3 0 0 58 164 1 1
MAX RBBP7 0 900 86 908 1 1
MAX PTMA 0 0 155 168 1 1
MAX HSPA2 0 0 0 181 1 1
MAX NFYC 0 900 0 902 1 1
MAX SMOC1 0 0 111 200 1 1
MAX ARNT2 0 0 94 297 1 1
MAX HMG20A 128 0 0 154 1 1
MAX MLX 0 0 341 528 1 1
MAX SIN3A 499 900 328 970 1 1
MAX TTC23 0 0 72 150 1 1
MAX TJP2 0 900 0 900 1 1
MAX TAF7 0 900 0 906 1 1
MAX FBXW2 0 0 0 181 1 1
MAX ARNTL 128 0 68 163 1 1
MAX BTK 0 0 66 162 1 1
MAX EZH1 0 0 0 206 1 1
MAX CIC 0 0 0 170 1 1
MAX PPP2R1A 270 0 0 274 1 1
MAX AZIN1 0 0 74 179 1 1
MAX CCND2 0 0 161 194 1 1
MAX KMT2A 0 900 0 904 1 1
MAX CSNK2A1 463 0 162 536 1 1
MAX DUX4L1 0 0 0 160 1 1
MAX SUPT7L 0 900 0 902 1 1
MAX ST7L 0 0 0 189 1 1
MAX FOXK2 212 0 108 278 1 1
MAX REST 0 0 84 459 1 2
MAX ENSG00000279229 0 0 218 218 1 1
MAX BLNK 0 0 72 198 1 1
MAX SUN5 0 0 0 154 1 1
MAX SAP30 0 900 0 900 1 1
MAX DUSP18 0 0 50 227 1 1
MAX MTF2 0 0 89 247 1 1
MAX SREBF2 0 0 74 150 1 1
MAX CCND1 0 0 153 186 1 2
MAX PPP2CA 270 900 0 925 1 1
MAX AHR 0 0 66 210 1 2
MAX WDR86 0 0 0 181 1 1
MAX EIF4E 0 0 150 174 1 2
MAX KAT2B 0 0 145 216 1 1
MAX RPS6KB1 0 0 114 177 1 2
MAX L3MBTL2 698 600 180 910 1 1
MAX MGA 676 900 556 985 1 1
MAX PIK3C2B 0 0 0 151 1 1
MAX HMGCR 0 0 0 432 1 1
MAX FBXL4 0 0 97 159 1 1
MAX POU5F1 270 0 141 406 1 2
MAX ZNF507 0 0 134 521 1 1
MAX CCNE1 0 650 47 654 1 1
MAX DMAP1 681 0 67 717 1 1
MAX FH 0 0 464 463 1 1
MAX SAP18 0 900 47 912 1 1
MAX TAL1 0 0 63 282 1 1
MAX MRGBP 270 0 0 302 1 1
MAX GFI1 0 900 45 902 1 1
MAX SYCP3 0 0 120 183 1 1
MAX TAF10 0 900 0 900 1 1
MAX E2F8 0 0 123 152 1 1
MAX PALLD 0 0 444 444 1 1
MAX HINFP 0 0 88 180 1 1
MAX MYRFL 0 0 96 158 1 1
MAX LDHA 0 0 184 183 1 2
MAX TCF4 0 0 161 342 1 1
MAX CHURC1-FNTB 0 0 156 157 1 1
MAX PTRF 128 0 0 313 1 1
MAX NFE2L1 0 0 0 199 1 1
MAX PRAME 0 0 0 187 1 1
MAX RPL34 71 0 86 179 1 1
MAX KAT5 486 900 153 954 1 1
MAX MAPK14 600 900 481 977 1 2
MAX E2F3 0 0 213 239 1 1
MAX CDX2 0 0 81 223 1 1
MAX YDJC 0 0 142 174 1 1
MAX KDM5C 422 0 74 505 1 1
MAX NFIA 0 0 55 151 1 1
MAX SNIP1 270 0 54 292 1 1
MAX ATP9A 0 0 0 158 1 1
MAX VEGFA 0 0 155 154 1 2
MAX TXN2 0 0 0 161 1 1
MAX PTEN 0 0 194 223 1 2
MAX HBP1 0 900 0 915 1 1
MAX MYOD1 0 0 181 196 1 1
MAX CASP5 213 0 74 245 1 1
MAX TRAF7 0 0 0 181 1 1
MAX UBN1 273 0 0 273 1 1
MAX PI4KB 0 0 0 153 1 1
MAX E2F5 0 0 134 162 1 1
MAX HCFC2 0 360 0 445 1 1
MAX EGLN2 0 0 218 224 1 1
MAX SMARCC2 0 0 108 156 1 1
MAX CHD4 0 0 74 196 1 1
MAX RYBP 392 0 92 424 1 1
MAX AXIN1 0 900 56 903 1 1
MAX TEAD1 270 0 60 394 1 1
MAX NHLH1 0 0 98 670 1 1
MAX RET 0 0 556 556 1 1
MAX THAP11 128 0 0 152 1 1
MAX ENSG00000267261 0 0 0 177 1 1
MAX POLI 0 0 207 217 1 1
MAX NBN 0 0 109 170 1 1
MAX TXLNG 130 0 0 155 1 1
MAX HNRNPK 0 0 73 154 1 1
MAX TBP 229 0 143 342 1 1
MAX TERT 0 900 134 910 1 2
MAX STRA8 0 0 100 156 1 1
MAX KSR1 270 0 46 324 1 1
MAX DYNC1H1 287 0 0 286 1 1
MAX ECHDC3 0 0 114 177 1 1
MAX BRD8 629 0 74 671 1 1
MAX ATOH7 0 0 0 157 1 1
MAX CBX1 271 0 0 271 1 1
MAX UBTF 0 0 122 151 1 1
MAX SMARCA4 0 0 161 222 1 1
MAX TLE3 0 0 0 153 1 1
MAX MAZ 0 0 509 520 1 1
MAX H2AFY 220 0 0 220 1 1
MAX SENP3 0 900 0 902 1 1
MAX ACTL6B 270 0 0 317 1 1
MAX EHMT1 0 600 0 638 1 1
MAX ESR1 0 0 181 204 1 2
MAX MSH2 632 0 50 643 1 1
MAX PPP1CA 128 0 0 203 1 1
MAX RBBP4 0 900 61 904 1 1
MAX NCL 0 0 161 161 1 2
MAX PIK3CB 0 0 0 158 1 1
MAX CDKN2B 0 0 128 170 1 1
MAX MAPK11 0 900 53 901 1 1
MAX CAD 0 0 0 182 1 2
MAX TMBIM1 0 0 150 169 1 1
MAX ASH2L 0 360 60 476 1 1
MAX TBX22 0 0 74 224 1 1
MAX GIT2 131 0 72 159 1 1
MAX CDT1 0 0 60 185 1 1
MAX CD72 0 0 0 189 1 1
MAX AMACR 0 0 0 206 1 1
MAX CDC25A 0 900 135 915 1 1
MAX PSMD9 131 0 88 194 1 1
MAX FRMD6 0 0 0 151 1 1
MAX RXRA 0 0 142 167 1 1
MAX FIGLA 0 0 74 298 1 1
MAX KDM6B 0 0 0 183 1 1
MAX FOS 0 0 155 213 1 2
MAX FBRS 0 0 202 231 1 1
MAX BSX 0 0 0 156 1 1
MAX EPAS1 270 0 464 616 1 2
MAX TAF12 0 900 0 900 1 1
MAX KRAS 0 0 94 165 1 2
MAX SPAG4 0 0 0 154 1 1
MAX WDR4 0 0 0 170 1 1
MAX CDK9 0 0 100 280 1 1
MAX FBXW10 0 0 0 181 1 1
MAX FOXK1 199 0 122 291 1 1
MAX E2F1 0 900 243 933 1 2
MAX TFE3 0 0 113 501 1 2
MAX USF2 0 0 278 181 1 1
MAX MRPL36 128 0 112 192 1 1
MAX GTF2E1 0 0 130 165 1 1
MAX DUX4 0 0 0 160 1 1
MAX CDKN2A 0 900 164 914 1 2
MAX EPHA3 0 0 43 163 1 1
MAX CSTF2 621 0 0 621 1 1
MAX GSK3B 0 900 47 904 1 2
MAX PBRM1 0 0 49 152 1 1
MAX PHC3 0 0 0 252 1 1
MAX BRF2 0 0 0 319 1 1
MAX MORF4L1 270 0 0 292 1 1
MAX HDAC1 0 900 148 913 1 2
MAX PSMD3 0 0 122 361 1 1
MAX TWIST2 0 0 96 160 1 1
MAX CHD8 0 900 0 906 1 1
MAX CEBPB 0 0 185 242 1 2
MAX PIK3CD 0 0 0 158 1 1
MAX MEF2A 0 0 97 167 1 1
MAX CDC27 0 0 0 200 1 1
MAX KANSL1 0 900 0 900 1 1
MAX KAT8 0 900 0 902 1 1
MAX EGLN1 0 0 391 399 1 1
MAX TAF6 0 900 0 905 1 1
MAX BHLHA15 0 0 0 229 1 1
MAX RAD21 270 0 112 336 1 1
MAX NR2C2 0 0 112 157 1 1
MAX SMARCA1 209 0 0 230 1 1
MAX ENSG00000267140 0 900 0 902 1 1
MAX BAZ1A 94 0 0 173 1 1
MAX DDX18 0 0 537 544 1 1
MAX ELK1 0 0 241 257 1 1
MAX CDK2 0 650 167 708 1 2
MAX CTNNB1 0 0 180 207 1 2
MAX HRAS 0 0 235 277 1 2
MAX CDC73 0 0 0 156 1 1
MAX L3MBTL1 0 0 81 235 1 1
MAX NDRG1 0 0 142 166 1 1
MAX MAPK13 0 900 0 900 1 1
MAX GABPA 0 0 118 218 1 1
MAX PAX2 0 0 0 183 1 1
MAX HIF1A 270 0 700 785 1 2
MAX SP1 0 0 156 208 1 2
MAX BRD2 0 0 81 176 1 1
MAX CBX3 382 600 0 754 1 1
MAX E2F6 433 900 260 956 1 1
MAX MYOG 0 0 134 267 1 1
MAX BICC1 0 0 0 213 1 1
MAX CPS1 0 0 0 154 1 1
MAX NFYB 0 900 0 901 1 1
MAX MSC 0 0 0 381 1 1
MAX IQCG 0 0 433 619 1 1
MAX TRIB2 0 0 0 152 1 1
MAX MTOR 131 0 218 428 1 2
MAX JARID2 0 0 48 150 1 1
MAX E2F2 0 0 174 212 1 1
MAX HIST1H4F 270 0 89 317 1 1
MAX DUX4L5 0 0 0 160 1 1
MAX NOTCH1 0 0 123 189 1 2
MAX AEBP2 0 0 207 221 1 1
MAX C1QL4 0 0 150 181 1 1
MAX CCNB1 0 0 124 163 1 1
MAX GLOD4 209 0 0 209 1 1
MAX BAP1 0 0 135 174 1 1
MAX APC 0 0 0 173 1 1
MAX CREB1 0 0 135 272 1 2
MAX EP400 853 0 444 918 1 1
MAX LONP1 0 0 60 240 1 1
MAX SDHB 0 0 560 563 1 1
MAX CREBBP 0 900 117 918 1 1
MAX ST7 0 0 142 371 1 1
MAX GRHL1 0 0 0 199 1 1
MAX UTF1 0 0 430 467 1 1
MAX TRAK1 0 0 0 274 1 1
MAX SMG1 0 0 47 166 1 1
MAX ATRX 0 0 142 253 1 1
MAX NF1 0 0 558 558 1 1
MAX FRMD1 0 0 0 151 1 1
MAX EPC2 270 0 0 281 1 1
MAX SMAD2 0 900 49 904 1 2
MAX PML 0 900 0 903 1 2
MAX GEMIN7 0 0 108 159 1 1
MAX GAPDH 0 0 170 187 1 2
MAX AZIN2 0 0 91 315 1 1
MAX BFSP2 257 0 0 256 1 1
MAX TBC1D12 0 0 51 198 1 1
MAX LRRC3C 0 0 205 332 1 1
MAX HIRA 273 0 0 273 1 1
MAX DNMT3A 0 900 134 912 1 2
MAX PELP1 0 900 0 900 1 2
MAX SPDL1 270 0 0 270 1 1
MAX BCL2L1 0 0 150 164 1 2
MAX TMEM127 0 0 751 818 1 1
MAX CBX4 0 0 0 297 1 1
MAX PIK3CA 0 0 103 335 1 2
MAX MEN1 0 0 142 157 1 1
MAX PIM1 270 900 75 929 1 1
MAX CASP8AP2 0 0 47 172 1 1
MAX RUVBL2 270 900 155 941 1 1
MAX SDHC 128 0 459 552 1 1
MAX USF1 270 0 422 389 1 1
MAX SDHAF2 0 0 607 615 1 1
MAX FOXR2 415 0 0 424 1 1
MAX PDK1 0 0 102 163 1 2
MAX PPRC1 0 0 134 213 1 1
MAX MYC 998 900 989 999 1 2
MAX CDRT1 0 0 0 181 1 1
MAX CLOCK 131 0 53 152 1 2
MAX APC2 0 0 0 173 1 1
MAX HNRNPU 270 0 0 270 1 1
MAX SCML2 0 0 0 155 1 1
MAX VPS72 270 0 0 289 1 1
MAX TCF3 0 0 102 359 1 1
MAX ODC1 0 0 325 361 1 1
MAX NCOA7 0 0 184 246 1 1
MAX FBXW8 0 0 46 185 1 1
MAX MECP2 94 0 74 156 1 1
MAX EHMT2 0 600 59 619 1 2
MAX FBXO16 0 0 0 181 1 1
MAX PLEKHA5 71 0 0 155 1 1
MAX SND1 479 0 0 479 1 1
MAX HDAC3 0 900 47 902 1 2
MAX MYCN 897 0 895 932 1 1
MAX SMAD4 270 900 105 930 1 2
MAX CHGA 0 0 193 248 1 1
MAX FBXO24 0 0 0 181 1 1
MAX TFEC 0 0 66 176 1 1
MAX CCNT1 270 0 67 411 1 1
MAX TRAK2 0 0 81 238 1 1
MAX HDAC2 128 900 81 915 1 1
MAX HK2 0 0 142 275 1 2
MAX HAND1 0 0 112 421 1 1
MAX MXD4 753 0 452 870 1 1
MAX TFAP4 0 0 74 394 1 1
MAX PPP1CC 128 0 0 202 1 1
MAX CDK4 0 0 172 205 1 2
MAX EGFR 0 0 155 169 1 2
MAX TAF9 0 900 60 903 1 1
MAX MDM2 0 0 226 225 1 2
MAX TP53 0 0 321 336 1 2
MAX USP37 270 0 53 306 1 1
MAX ZNF143 0 0 61 208 1 1
MAX NCOA1 0 0 113 211 1 1
MAX EFCAB8 0 0 0 181 1 1
MAX EZH2 0 0 151 203 1 2
MAX HNRNPH2 271 0 0 274 1 1
MAX PRPF31 0 900 0 904 1 1
MAX TCF21 0 0 0 270 1 1
MAX BRF1 0 0 0 319 1 1
MAX PIN1 0 900 69 905 1 1
MAX ATP9B 0 0 0 158 1 1
MAX HUWE1 0 900 67 909 1 1
MAX BRD4 0 0 205 287 1 2
MAX BAG6 0 0 67 331 1 1
MAX ACTR8 0 0 43 155 1 1
MAX PUF60 0 0 0 233 1 1
MAX SMAD3 632 900 107 965 1 2
MAX ZMIZ1 0 0 66 177 1 1
MAX MAD1L1 213 0 0 213 1 1
MAX EP300 675 900 300 977 1 2
MAX LIG3 224 0 0 235 1 1
MAX HCFC1 0 900 87 916 1 1
MAX DUX4L3 0 0 0 160 1 1
MAX KAT2A 486 900 181 958 1 1
MAX CASP7 213 0 67 240 1 1
MAX USP28 0 0 139 187 1 1
MAX INO80C 0 900 0 902 1 1
MAX YAF2 392 600 87 760 1 1
MAX SUN2 0 0 0 160 1 1
MAX CTR9 0 0 0 162 1 1
MAX PPP2R1B 270 0 45 278 1 1
MAX SDHA 0 0 547 557 1 1
MAX SUN1 0 0 0 161 1 1
MAX PPP1CB 128 0 0 202 1 1
MAX PLEKHH2 0 0 0 250 1 1
MAX GTF3C2 0 0 212 260 1 1
MAX PPP2R5A 0 900 0 900 1 1
MAX MLXIPL 0 0 339 487 1 1
MAX IDH1 0 0 150 180 1 1
MAX MORF4L2 270 0 0 270 1 1
MAX FBXO28 0 0 90 160 1 1
MAX XRN2 0 0 0 150 1 1
MAX HLF 0 0 218 666 1 1
MAX R3HCC1 0 0 206 206 1 1
MAX MYCBP 0 0 167 247 1 1
MAX CD79B 0 0 72 198 1 1
MAX TRIM16L 0 0 0 181 1 1
MAX PAK2 0 900 441 955 1 1
MAX MBTD1 270 0 0 329 1 1
MAX RUVBL1 270 900 117 937 1 1
MAX SKP2 0 900 94 908 1 2
MAX BAZ1B 0 0 57 229 1 1
MAX TDP2 0 0 0 163 1 1
MAX NR3C1 0 0 119 162 1 1
MAX PPP2CB 270 0 0 281 1 1
MAX SMARCB1 0 0 188 264 1 1
MAX OSBPL7 0 0 161 161 1 1
MAX CDX1 0 0 95 180 1 1
MAX HIST2H3PS2 0 0 203 217 1 1
MAX CSDE1 0 0 216 317 1 1
MAX RPTOR 0 0 101 190 1 2
MAX MYCL 745 0 696 804 1 1
MAX PCGF1 0 0 90 312 1 1
MAX BPTF 0 0 67 248 1 1
MAX DUX4L6 0 0 0 160 1 1
MAX TRIB1 0 0 55 251 1 1
MAX NFYA 0 900 0 902 1 1
MAX ARL6IP5 271 0 0 271 1 1
MAX SCMH1 0 0 0 244 1 1
MAX SMARCA5 216 0 92 313 1 1
MAX ETS1 0 0 135 192 1 1
MAX MLXIP 0 0 325 476 1 1
MAX NANOG 0 0 95 408 1 2
MAX HK1 71 0 0 163 1 1
MAX KIF1B 44 0 402 403 1 1
MAX HSPA1A 270 0 0 298 1 1
MAX SLC25A31 0 0 96 167 1 1
MAX SRF 0 0 149 181 1 1
MAX JAK3 0 0 93 165 1 1
MAX PIK3CG 0 0 44 152 1 1
MAX GRHL2 0 0 0 199 1 1
MAX SLC16A3 0 0 60 169 1 1
MAX ECT2L 0 0 0 181 1 1
MAX PHF21A 128 0 0 151 1 1
MAX SAP130 275 0 170 402 1 1
MAX RHBDD2 0 0 53 215 1 1
MAX JUN 131 0 234 331 1 2
MAX ASF1A 273 0 0 311 1 1
MAX TAF1 130 900 125 920 1 1
MAX WDR5 376 900 113 945 1 1
MAX HNRNPA1 0 0 157 176 1 1
MAX MEAF6 270 0 0 286 1 1
MAX PLEKHH1 0 0 0 404 1 1
MAX MAPK12 0 900 0 900 1 1
MAX DUX4L2 0 0 0 160 1 1
MAX BRD3 0 0 67 161 1 1
MAX ARNT 0 0 181 374 1 2
MAX TEX10 0 900 0 900 1 1
MAX MNT 754 0 777 814 1 1
MAX AIP 71 0 120 166 1 1
MAX PNMT 0 0 287 293 1 1
MAX ABI1 0 0 0 175 1 1
MAX ATF7IP 0 0 93 154 1 1
MAX BASP1 0 0 134 157 1 1
MAX CREB3 0 0 293 293 1 1
MAX CPSF6 631 0 0 639 1 1
MAX ZBTB17 270 900 296 945 1 1
MAX ZBTB7A 0 0 0 162 1 1
MAX RING1 386 600 52 783 1 1
MAX KDM1A 128 0 46 243 1 2
MAX WDR74 0 0 0 177 1 1
MAX AURKA 0 0 161 181 1 2
MAX ENSG00000251537 0 0 0 181 1 1
MAX HNRNPH1 270 0 0 273 1 1
MAX CDKN1A 0 0 240 305 1 2
MAX MXI1 897 0 745 975 1 1
MAX EPC1 270 0 0 281 1 1
MAX WDR48 0 0 0 181 1 1
MAX PCGF6 743 600 276 926 1 1
MAX ATF2 0 0 144 338 1 1
MAX CEBPA 270 0 60 344 1 1
MAX SOX2 0 0 113 254 1 2
MAX UNC45A 604 0 0 604 1 1
MAX DUX4L8 0 0 0 160 1 1
MAX FBXW7 270 900 122 941 1 2
MAX HSP90AA1 129 0 95 214 1 2
MAX TFEB 0 0 42 155 1 2
MAX SPAG9 270 0 0 270 1 1
MAX BCL3 0 0 165 194 1 1
MAX TFDP1 679 600 155 888 1 1
MAX ING3 270 0 0 270 1 1
MAX PAX5 0 0 68 206 1 1
MAX PRDM14 270 0 0 282 1 1
MAX YEATS4 585 0 0 611 1 1
MAX AK6 270 900 0 931 1 1
MAX MXD3 871 0 374 922 1 1
MAX ACTB 0 0 165 184 1 2
Ontologies
ID Category Term Effect Evidence PubMed
GO:0003677 Molecular Function DNA binding enables IDA
GO:0003700 Molecular Function DNA-binding transcription factor activity enables IBA
GO:0000981 Molecular Function DNA-binding transcription factor activity, RNA polymerase II-specific enables IDA
GO:0000981 Molecular Function DNA-binding transcription factor activity, RNA polymerase II-specific enables ISA
GO:0140297 Molecular Function DNA-binding transcription factor binding enables IPI
GO:0001227 Molecular Function DNA-binding transcription repressor activity, RNA polymerase II-specific contributes_to IDA
GO:0001227 Molecular Function DNA-binding transcription repressor activity, RNA polymerase II-specific enables IDA
GO:0070888 Molecular Function E-box binding enables IMP
GO:0000977 Molecular Function RNA polymerase II transcription regulatory region sequence-specific DNA binding contributes_to IDA
GO:0005515 Molecular Function protein binding enables IPI
GO:0046983 Molecular Function protein dimerization activity enables IEA
GO:1990837 Molecular Function sequence-specific double-stranded DNA binding enables IDA
GO:0000122 Biological Process negative regulation of transcription by RNA polymerase II involved_in IDA
GO:0045893 Biological Process positive regulation of DNA-templated transcription involved_in IDA
GO:0045944 Biological Process positive regulation of transcription by RNA polymerase II involved_in IBA
GO:0006357 Biological Process regulation of transcription by RNA polymerase II involved_in IDA
GO:0071339 Cellular Component MLL1 complex part_of IDA
GO:0070443 Cellular Component Mad-Max complex part_of IPI
GO:0071943 Cellular Component Myc-Max complex part_of IPI
GO:0090575 Cellular Component RNA polymerase II transcription regulator complex part_of IBA
GO:0090575 Cellular Component RNA polymerase II transcription regulator complex part_of IDA
GO:0000785 Cellular Component chromatin part_of IDA
GO:0000785 Cellular Component chromatin part_of ISA
GO:0030425 Cellular Component dendrite located_in IEA
GO:0005654 Cellular Component nucleoplasm located_in TAS
GO:0005634 Cellular Component nucleus located_in IDA
GO:0005634 Cellular Component nucleus located_in NAS
GO:0032993 Cellular Component protein-DNA complex part_of IDA
GO:0032993 Cellular Component protein-DNA complex part_of IMP
Pathways
Name DB ID
Transcription of E2F targets under negative control by DREAM complex Reactome R-HSA-1362277
G0 and Early G1 Reactome R-HSA-1538133
Cell Cycle Reactome R-HSA-1640170
Generic Transcription Pathway Reactome R-HSA-212436
Mitotic G1 phase and G1/S transition Reactome R-HSA-453279
Cyclin E associated events during G1/S transition Reactome R-HSA-69202
G1/S Transition Reactome R-HSA-69206
S Phase Reactome R-HSA-69242
Cell Cycle, Mitotic Reactome R-HSA-69278
Cyclin A:Cdk2-associated events at S phase entry Reactome R-HSA-69656
RNA Polymerase II Transcription Reactome R-HSA-73857
Gene expression (Transcription) Reactome R-HSA-74160
Transcriptional Regulation by E2F6 Reactome R-HSA-8953750
Pathways affected in adenoid cystic carcinoma (WP3651) WikiPathways WP3651_r122573
p38 MAPK signaling pathway (WP400) WikiPathways WP400_r123111
MAPK signaling pathway (WP382) WikiPathways WP382_r119087
Small cell lung cancer (WP4658) WikiPathways WP4658_r124606
B cell receptor signaling pathway (WP23) WikiPathways WP23_r120701
Malignant pleural mesothelioma (WP5087) WikiPathways WP5087_r122659
Transcripts
Accession Version MolecularType Name NCBI Comments
NR_073137 2 miscRNA transcript variant 9 NC_000014 Reference
NR_176282 1 miscRNA transcript variant 40 NC_000014 Reference
NR_176278 1 miscRNA transcript variant 36 NC_000014 Reference
NR_176280 1 miscRNA transcript variant 38 NC_000014 Reference
NR_176275 1 miscRNA transcript variant 33 NC_000014 Reference
NR_176281 1 miscRNA transcript variant 39 NC_000014 Reference
NR_176279 1 miscRNA transcript variant 37 NC_000014 Reference
NR_073138 2 miscRNA transcript variant 10 NC_000014 Reference
NR_176283 1 miscRNA transcript variant 41 NC_000014 Reference
NR_176277 1 miscRNA transcript variant 35 NC_000014 Reference
NR_176276 1 miscRNA transcript variant 34 NC_000014 Reference
NM_001271069 2 mRNA transcript variant 8 NC_000014 Reference
NM_197957 4 mRNA transcript variant 6 NC_000014 Reference
NM_001407112 1 mRNA transcript variant 30 NC_000014 Reference
NM_001407106 1 mRNA transcript variant 24 NC_000014 Reference
NM_001407095 1 mRNA transcript variant 13 NC_000014 Reference
NM_001407107 1 mRNA transcript variant 25 NC_000014 Reference
NM_001407110 1 mRNA transcript variant 28 NC_000014 Reference
NM_001407102 1 mRNA transcript variant 20 NC_000014 Reference
NM_001407101 1 mRNA transcript variant 19 NC_000014 Reference
NM_001407094 1 mRNA transcript variant 12 NC_000014 Reference
NM_001407104 1 mRNA transcript variant 22 NC_000014 Reference
NM_001407103 1 mRNA transcript variant 21 NC_000014 Reference
NM_145112 3 mRNA transcript variant 2 NC_000014 Reference
NM_001407108 1 mRNA transcript variant 26 NC_000014 Reference
NM_001407109 1 mRNA transcript variant 27 NC_000014 Reference
NM_001407099 1 mRNA transcript variant 17 NC_000014 Reference
NM_001407100 1 mRNA transcript variant 18 NC_000014 Reference
NM_001407098 1 mRNA transcript variant 16 NC_000014 Reference
NM_002382 5 mRNA transcript variant 1 NC_000014 Reference
NM_001320415 2 mRNA transcript variant 11 NC_000014 Reference
NM_145113 3 mRNA transcript variant 3 NC_000014 Reference
NM_001407096 1 mRNA transcript variant 14 NC_000014 Reference
NM_001407097 1 mRNA transcript variant 15 NC_000014 Reference
NM_001407105 1 mRNA transcript variant 23 NC_000014 Reference
NM_001407111 1 mRNA transcript variant 29 NC_000014 Reference
XM_011536773 4 mRNA transcript variant X1 NC_000014 Reference
NM_001407113 1 mRNA transcript variant 31 NC_000014 Reference
NM_001271068 2 mRNA transcript variant 7 NC_000014 Reference
NM_145114 3 mRNA transcript variant 4 NC_000014 Reference
NM_001407114 1 mRNA transcript variant 32 NC_000014 Reference