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MMP13

matrix metallopeptidase 13
General Information
Name matrix metallopeptidase 13
Alias
  • collagenase 3
  • matrix metalloproteinase 13 (collagenase 3)
Gene_family M10 matrix metallopeptidases|Receptor ligands
organism Homo sapiens
entrez_id 4322
location 11q22.2
transcript_count 1
exon_count 10
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. Mutations in this gene are associated with metaphyseal anadysplasia. This gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016]
    Stringdb Collagenase 3; Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CTGF. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bon [...]
    nextProt Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CCN2. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Required for normal embryonic bone development and ossification. Plays a role in the healing of bone fractures via endochondral ossification. Plays a role in wound healing, probably by a mechanism that involves proteolytic activation of TGFB1 and degradation of CCN2. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion.
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
MMP13 BioGRID MMP24 GeneID BioGRID Negative Genetic
MMP13 BioGRID MMP20 GeneID BioGRID Negative Genetic
MMP13 BioGRID MMP16 GeneID BioGRID Negative Genetic
MMP13 BioGRID MMP11 GeneID BioGRID Negative Genetic
MMP13 BioGRID MMP10 GeneID BioGRID Negative Genetic
MMP13 BioGRID MMP8 GeneID BioGRID Negative Genetic
MMP13 BioGRID MMP7 GeneID BioGRID Negative Genetic
MMP13 BioGRID FBXO45 GeneID BioGRID Affinity Capture-MS
MMP13 BioGRID SPRYD3 GeneID BioGRID Affinity Capture-MS
MMP13 BioGRID WDR26 GeneID BioGRID Affinity Capture-MS
MMP13 BioGRID PEAK1 GeneID BioGRID Affinity Capture-MS
MMP13 BioGRID GID4 GeneID BioGRID Affinity Capture-MS
MMP13 BioGRID RANBP10 GeneID BioGRID Affinity Capture-MS
MMP13 BioGRID HTRA2 GeneID BioGRID Affinity Capture-MS
MMP13 BioGRID KIFBP GeneID BioGRID Affinity Capture-MS
MMP13 BioGRID ARMC8 GeneID BioGRID Affinity Capture-MS
MMP13 BioGRID MYCBP2 GeneID BioGRID Affinity Capture-MS
MMP13 BioGRID MAEA GeneID BioGRID Affinity Capture-MS
MMP13 BioGRID ADAMTS2 GeneID BioGRID Affinity Capture-MS
MMP13 BioGRID MKLN1 GeneID BioGRID Affinity Capture-MS
MMP13 BioGRID CS GeneID BioGRID Affinity Capture-MS
MMP13 BioGRID FBXO7 GeneID BioGRID Biochemical Activity
MMP13 Protein ADAMTS5 GeneID HPRD
MMP13 Protein MMP14 GeneID HPRD
MMP13 Protein BCAN GeneID HPRD
MMP13 Protein MMP13 GeneID HPRD
MMP13 Protein F12 GeneID HPRD
MMP13 Protein TIMP3 GeneID HPRD
MMP13 Protein CCL7 GeneID HPRD
MMP13 Protein COL2A1 GeneID HPRD
MMP13 Protein LRP1 GeneID HPRD
MMP13 BioGRID BCAN GeneID BioGRID Biochemical Activity
StringDB
A B experiments database textmining combined score hadb nhadb
MMP13 CNOT7 0 0 0 162 1 1
MMP13 TRAF6 0 0 294 304 1 2
MMP13 NANOG 0 0 167 185 1 2
MMP13 VCAN 0 0 454 454 1 1
MMP13 CASP9 0 0 240 239 1 2
MMP13 TLR7 0 0 135 170 1 2
MMP13 MAPK9 0 0 174 183 1 2
MMP13 IL13RA2 0 0 306 306 1 1
MMP13 CXCL11 0 0 165 165 1 1
MMP13 CYCS 0 0 150 203 1 2
MMP13 CHAD 0 0 248 248 1 1
MMP13 PLGLB1 0 0 155 248 1 1
MMP13 GADD45B 0 0 262 262 1 1
MMP13 BMP2 0 0 564 564 1 1
MMP13 EGF 0 0 401 462 1 2
MMP13 PRTN3 0 0 138 161 1 1
MMP13 PLAU 0 0 404 438 1 1
MMP13 IGFBP1 0 0 124 173 1 1
MMP13 IL17A 0 0 468 468 1 2
MMP13 ETS1 0 0 325 325 1 1
MMP13 HAS1 0 0 158 179 1 1
MMP13 RAB31 0 0 0 172 1 1
MMP13 LIF 0 0 161 161 1 2
MMP13 ACVR1 0 0 150 203 1 1
MMP13 HSPA4 0 0 150 186 1 1
MMP13 COL5A1 0 0 335 348 1 1
MMP13 PLAUR 0 0 324 350 1 1
MMP13 DICER1 0 0 181 181 1 1
MMP13 CX3CR1 0 0 202 202 1 1
MMP13 CCR2 0 0 310 321 1 2
MMP13 TIE1 0 0 74 230 1 1
MMP13 NES 0 0 166 165 1 2
MMP13 CYP2E1 0 0 150 179 1 2
MMP13 MRC2 0 0 422 422 1 1
MMP13 ITGA1 0 0 210 235 1 1
MMP13 TEK 0 0 149 263 1 1
MMP13 CXCL9 0 0 277 291 1 1
MMP13 FBXO7 270 0 0 270 1 1
MMP13 PPARA 0 0 289 288 1 2
MMP13 MMP16 0 900 596 910 1 1
MMP13 IL1F10 0 0 103 502 1 1
MMP13 HIST2H3PS2 0 0 207 207 1 1
MMP13 PXN 0 0 145 227 1 1
MMP13 PRR4 0 0 194 194 1 1
MMP13 TPM2 0 0 70 168 1 1
MMP13 GDPD5 0 0 0 196 1 1
MMP13 COL4A1 0 0 282 296 1 1
MMP13 P2RX7 0 0 142 160 1 2
MMP13 CTGF 0 0 507 557 1 1
MMP13 CCR1 0 0 206 273 1 1
MMP13 COL13A1 0 0 134 168 1 1
MMP13 NR3C1 0 0 202 202 1 1
MMP13 PDGFA 0 0 170 169 1 1
MMP13 CISH 0 0 181 212 1 1
MMP13 PTGER4 0 0 224 236 1 1
MMP13 PTK2 0 0 267 267 1 2
MMP13 ADIPOQ 0 0 338 338 1 2
MMP13 LTBP1 0 0 166 183 1 1
MMP13 FRZB 0 0 369 404 1 1
MMP13 VIM 0 0 156 174 1 2
MMP13 ARG1 0 0 294 306 1 2
MMP13 BMP1 0 500 280 624 1 1
MMP13 ADAM11 0 0 140 159 1 1
MMP13 MAPK8 0 0 320 324 1 2
MMP13 CALCA 0 0 235 235 1 1
MMP13 PHOSPHO1 0 0 233 232 1 1
MMP13 MUT 0 0 159 158 1 1
MMP13 FGF18 0 0 372 415 1 1
MMP13 BRAF 0 0 48 218 1 2
MMP13 ADAMTS2 0 0 374 390 1 1
MMP13 ATP6V0D2 0 0 166 316 1 1
MMP13 ITGA7 0 0 140 167 1 1
MMP13 API5 0 0 0 213 1 1
MMP13 AGER 0 0 325 325 1 2
MMP13 TMOD4 0 0 0 163 1 1
MMP13 MATN1 0 0 338 351 1 1
MMP13 GLI2 0 0 247 246 1 2
MMP13 ACTC1 0 0 96 252 1 1
MMP13 SIRT6 0 0 202 203 1 2
MMP13 WNT16 0 0 253 301 1 1
MMP13 CDK6 0 0 150 203 1 2
MMP13 PLG 0 900 458 949 1 1
MMP13 ZEB2 0 0 204 204 1 1
MMP13 CDH1 0 0 425 446 1 2
MMP13 TPM4 0 0 60 159 1 1
MMP13 PDPN 0 0 150 172 1 1
MMP13 ADAMTS10 0 0 123 177 1 1
MMP13 BMP7 0 0 505 505 1 1
MMP13 FKBP5 0 0 141 226 1 1
MMP13 DPP4 0 0 271 271 1 1
MMP13 LOXL2 0 0 265 265 1 1
MMP13 EREG 0 0 163 194 1 1
MMP13 BSG 0 0 293 337 1 1
MMP13 CSN2 0 0 141 164 1 1
MMP13 CCL4 0 0 325 350 1 1
MMP13 IL1A 0 0 560 569 1 1
MMP13 SRGN 0 0 507 507 1 1
MMP13 ROCK2 0 0 134 157 1 1
MMP13 WNT1 0 0 265 279 1 2
MMP13 LEPR 0 0 195 195 1 1
MMP13 SNAI2 0 0 286 286 1 1
MMP13 RPL19 0 0 140 205 1 1
MMP13 CCL2 0 0 556 566 1 2
MMP13 ALB 0 0 468 581 1 2
MMP13 CASP8 0 0 193 210 1 2
MMP13 CD68 0 0 381 388 1 2
MMP13 ITGB1 0 0 293 350 1 1
MMP13 FAP 0 0 164 163 1 2
MMP13 HSPG2 0 900 390 936 1 1
MMP13 CASP7 0 0 155 154 1 1
MMP13 USP28 0 0 0 188 1 1
MMP13 CSGALNACT1 0 0 150 179 1 1
MMP13 THBS4 0 0 150 181 1 1
MMP13 LEF1 0 0 253 252 1 1
MMP13 PDGFRB 0 0 193 203 1 2
MMP13 ENPP2 0 0 123 202 1 1
MMP13 EP300 0 0 203 297 1 2
MMP13 ADIPOR1 0 0 181 181 1 1
MMP13 NOTCH3 0 0 134 175 1 1
MMP13 WNT9B 0 0 134 151 1 1
MMP13 IL4 0 0 421 420 1 1
MMP13 SPARC 0 0 456 467 1 2
MMP13 SMAD3 0 0 467 508 1 2
MMP13 IL17F 0 0 181 181 1 1
MMP13 FBLN1 0 0 150 255 1 1
MMP13 TNXB 0 0 150 175 1 1
MMP13 CNN2 0 0 86 286 1 1
MMP13 ROCK1 0 0 163 163 1 2
MMP13 EPRS 0 0 181 181 1 1
MMP13 SELL 0 0 142 184 1 1
MMP13 CD40 0 0 180 179 1 2
MMP13 WNT6 0 0 171 187 1 1
MMP13 FGF1 0 0 260 261 1 1
MMP13 CTTN 0 0 103 208 1 1
MMP13 FUT8 0 0 574 574 1 1
MMP13 DNMT1 0 0 193 193 1 2
MMP13 INS 0 0 391 408 1 2
MMP13 SELP 0 0 181 181 1 1
MMP13 ACTB 0 0 565 594 1 2
MMP13 ADAMTS5 213 0 870 906 1 1
MMP13 IL17B 0 0 150 180 1 1
MMP13 GLI3 0 0 166 165 1 1
MMP13 JUNB 0 0 260 265 1 1
MMP13 F12 213 0 0 239 1 1
MMP13 KEAP1 0 0 141 159 1 2
MMP13 MMP9 0 300 858 436 1 2
MMP13 B2M 0 0 240 284 1 1
MMP13 MAPK3 0 0 468 475 1 2
MMP13 THY1 0 0 310 309 1 1
MMP13 ANGPT1 0 0 210 240 1 1
MMP13 SIRT3 0 0 170 171 1 2
MMP13 TSKU 0 0 44 507 1 1
MMP13 PROM1 0 0 193 193 1 2
MMP13 SP7 0 0 556 556 1 1
MMP13 HDAC4 0 0 412 419 1 2
MMP13 IL21 0 0 54 439 1 1
MMP13 S100A11 0 0 181 213 1 1
MMP13 FOSL1 0 0 283 310 1 1
MMP13 HSP90AA1 0 0 183 194 1 2
MMP13 PSEN1 0 0 66 209 1 2
MMP13 COL14A1 0 900 235 924 1 1
MMP13 ATF2 0 0 119 162 1 1
MMP13 CRP 0 0 294 294 1 2
MMP13 SOX2 0 0 181 197 1 2
MMP13 PRSS1 0 900 62 902 1 1
MMP13 CEBPA 0 0 183 189 1 1
MMP13 SOST 0 0 504 512 1 1
MMP13 WISP2 0 0 190 207 1 1
MMP13 PTPRC 0 0 292 312 1 1
MMP13 OMD 0 0 218 218 1 1
MMP13 PRG4 0 0 562 565 1 1
MMP13 SENP6 0 0 134 188 1 1
MMP13 CXCR1 0 0 141 194 1 1
MMP13 ESR2 0 0 194 270 1 1
MMP13 ITGAV 0 0 290 290 1 1
MMP13 IGFBP2 0 0 150 187 1 1
MMP13 ICAM1 0 0 371 371 1 2
MMP13 SOX9 0 0 736 781 1 1
MMP13 SIRT7 0 0 180 181 1 2
MMP13 ZEB1 0 0 248 248 1 2
MMP13 CD24 0 0 142 158 1 2
MMP13 CPNE1 0 0 0 363 1 1
MMP13 ETV4 0 0 345 349 1 1
MMP13 GDF10 0 0 150 208 1 1
MMP13 EPCAM 0 0 141 167 1 2
MMP13 RHOA 0 0 267 267 1 2
MMP13 AR 0 0 189 206 1 2
MMP13 SOX8 0 0 97 252 1 1
MMP13 ITGA11 0 0 150 173 1 1
MMP13 CDKN1A 0 0 209 226 1 2
MMP13 SPP1 0 0 602 616 1 2
MMP13 GPR29 0 0 124 373 1 1
MMP13 IL36A 0 0 74 484 1 1
MMP13 AGA 0 0 0 180 1 1
MMP13 TIMP1 0 0 872 934 1 1
MMP13 KIAA1324 0 0 0 226 1 1
MMP13 FGF4 0 0 81 180 1 1
MMP13 MIP 0 0 0 248 1 1
MMP13 CXCL12 0 0 459 459 1 2
MMP13 TPM1 0 0 57 157 1 1
MMP13 CITED2 0 0 248 254 1 1
MMP13 IGFBP3 0 0 233 235 1 2
MMP13 SMAD1 0 0 57 162 1 2
MMP13 CD8A 0 0 247 246 1 1
MMP13 ADAM8 0 0 251 269 1 1
MMP13 BMP6 0 0 342 342 1 1
MMP13 COL3A1 0 0 518 538 1 1
MMP13 KRT8 0 0 142 231 1 1
MMP13 ANGPT2 0 0 150 259 1 1
MMP13 NEDD9 0 0 134 171 1 1
MMP13 NCOA3 0 0 149 192 1 1
MMP13 TCIRG1 0 0 57 154 1 1
MMP13 RUNX3 0 0 306 335 1 1
MMP13 MMP2 0 300 807 376 1 2
MMP13 GRN 0 0 166 185 1 1
MMP13 MIA 0 0 225 233 1 2
MMP13 IL17RA 0 0 205 205 1 1
MMP13 HYAL3 0 0 0 183 1 1
MMP13 ITGA10 0 0 161 161 1 1
MMP13 FST 0 0 141 213 1 1
MMP13 RPL4 0 0 60 201 1 1
MMP13 JAG1 0 0 193 209 1 1
MMP13 LAMB1 0 0 161 161 1 1
MMP13 LTA 0 0 147 352 1 1
MMP13 IL36RN 0 0 122 513 1 1
MMP13 IL37 0 0 49 456 1 1
MMP13 CCR5 0 0 202 220 1 1
MMP13 FGF6 0 0 49 254 1 1
MMP13 DCSTAMP 0 0 150 186 1 1
MMP13 SHH 0 0 243 257 1 2
MMP13 COMP 0 0 595 603 1 1
MMP13 SULF1 0 0 150 173 1 1
MMP13 IL10RA 0 0 123 152 1 1
MMP13 CDH17 0 0 193 207 1 1
MMP13 SERPINB2 0 0 216 250 1 1
MMP13 MAPK12 0 0 134 273 1 1
MMP13 SERPINA1 0 0 156 169 1 2
MMP13 ENSG00000173366 0 0 270 270 1 1
MMP13 CCL24 0 0 174 173 1 1
MMP13 XYLT1 0 0 181 181 1 1
MMP13 COL16A1 0 0 234 249 1 1
MMP13 JUN 0 0 562 576 1 2
MMP13 MKX 0 0 193 193 1 1
MMP13 FZD1 0 0 140 157 1 1
MMP13 DAPK1 0 0 70 198 1 2
MMP13 PLAT 0 0 357 425 1 1
MMP13 CXCL6 0 0 210 294 1 1
MMP13 DSC2 0 0 66 178 1 1
MMP13 CD74 0 0 119 176 1 1
MMP13 DNTT 0 0 233 232 1 1
MMP13 CCNA2 0 0 161 161 1 1
MMP13 CASP1 0 0 234 257 1 2
MMP13 CCR3 0 0 170 221 1 1
MMP13 COL18A1 0 900 244 924 1 1
MMP13 HIC1 0 0 0 252 1 1
MMP13 ZFP36 0 0 113 151 1 1
MMP13 CAV1 0 0 698 704 1 2
MMP13 TNFSF10 0 0 202 202 1 2
MMP13 GSTA4 0 0 141 172 1 1
MMP13 MAP2K3 0 0 232 231 1 1
MMP13 GJB2 0 0 433 433 1 1
MMP13 WIF1 0 0 181 181 1 1
MMP13 COL11A2 0 0 195 211 1 1
MMP13 KITLG 0 0 132 156 1 1
MMP13 CALCR 0 0 204 204 1 1
MMP13 MMP20 0 300 536 337 1 1
MMP13 LECT1 0 0 310 315 1 1
MMP13 SLC25A20 0 0 146 164 1 1
MMP13 NFKB1 0 0 193 223 1 2
MMP13 LAMC2 0 900 194 915 1 1
MMP13 HMGB2 0 0 123 274 1 1
MMP13 RELA 0 0 294 397 1 2
MMP13 CCDC167 0 0 139 178 1 1
MMP13 SPDL1 0 0 0 210 1 1
MMP13 BCL2L1 0 0 214 225 1 2
MMP13 ACKR3 0 0 124 157 1 1
MMP13 CCL4L1 0 0 201 231 1 1
MMP13 EMCN 0 0 161 161 1 1
MMP13 EMR1 0 0 95 217 1 1
MMP13 SMAD2 0 0 502 622 1 2
MMP13 TLR4 0 0 455 466 1 2
MMP13 PLGLB2 0 0 170 261 1 1
MMP13 FGFR2 0 0 236 236 1 1
MMP13 GAPDH 0 0 630 633 1 2
MMP13 GREM1 0 0 280 295 1 1
MMP13 ST3GAL2 0 0 0 186 1 1
MMP13 GGCT 0 0 0 159 1 1
MMP13 JAG2 0 0 180 198 1 1
MMP13 APOA1 0 0 137 184 1 1
MMP13 HYAL2 0 0 203 347 1 1
MMP13 NOS2 0 0 384 411 1 2
MMP13 CX3CL1 0 0 218 232 1 1
MMP13 MAP2K7 0 0 321 321 1 1
MMP13 RECK 0 0 218 270 1 1
MMP13 IGFBP5 0 0 294 294 1 1
MMP13 CREBBP 0 0 123 303 1 1
MMP13 BIRC2 0 0 120 150 1 1
MMP13 IFNG 0 0 321 363 1 2
MMP13 FGF14 0 0 57 265 1 1
MMP13 EFNB1 0 0 94 161 1 1
MMP13 CCL5 0 0 455 466 1 2
MMP13 TGFB3 0 0 556 556 1 1
MMP13 CREB1 0 0 260 260 1 2
MMP13 WNT8A 0 0 156 172 1 1
MMP13 ANXA5 0 0 323 337 1 2
MMP13 CCNB1 0 0 173 179 1 1
MMP13 OSMR 0 0 66 208 1 1
MMP13 FGF21 0 0 90 215 1 2
MMP13 TAGLN 0 0 306 403 1 1
MMP13 PCSK6 0 0 150 181 1 1
MMP13 PHEX 0 0 294 298 1 1
MMP13 CLEC4D 0 0 74 192 1 1
MMP13 SERPINI1 0 0 0 201 1 1
MMP13 SIRT2 0 0 172 173 1 2
MMP13 WNT11 0 0 193 208 1 1
MMP13 TNFSF18 0 0 72 235 1 1
MMP13 CA2 0 0 183 183 1 1
MMP13 CXCL13 0 0 216 216 1 1
MMP13 FGF13 0 0 398 425 1 1
MMP13 CYR61 0 0 208 213 1 1
MMP13 CXCR4 0 0 374 384 1 2
MMP13 MMP1 0 650 870 682 1 1
MMP13 NOTCH1 0 0 324 338 1 2
MMP13 PTGS1 0 0 170 194 1 1
MMP13 CD40LG 0 0 138 170 1 1
MMP13 MTOR 0 0 243 242 1 2
MMP13 RPL13A 0 0 232 245 1 1
MMP13 TIMP4 0 0 630 692 1 1
MMP13 POTEF 0 0 213 267 1 1
MMP13 SAA1 0 0 235 246 1 1
MMP13 CD163 0 0 242 241 1 1
MMP13 BMP3 0 0 171 177 1 1
MMP13 ACAN 0 900 870 988 1 1
MMP13 MPO 0 0 244 244 1 2
MMP13 ETS2 0 0 171 171 1 1
MMP13 ADAMTS16 0 0 263 294 1 1
MMP13 CTRL 0 0 155 154 1 2
MMP13 CXCL14 0 0 193 199 1 1
MMP13 IL6 0 0 686 705 1 2
MMP13 STAT1 0 0 315 315 1 2
MMP13 TNFRSF1A 0 0 276 291 1 1
MMP13 COL27A1 0 0 143 235 1 1
MMP13 IL17D 0 0 246 245 1 1
MMP13 KRT12 0 0 64 226 1 1
MMP13 CILP 0 0 267 351 1 1
MMP13 OCLN 0 0 141 200 1 1
MMP13 RSU1 0 0 117 163 1 1
MMP13 MMP21 0 0 358 151 1 1
MMP13 WNT7B 0 0 204 219 1 1
MMP13 HIF1A 0 0 459 459 1 2
MMP13 EDN1 0 0 260 291 1 1
MMP13 POSTN 0 0 406 485 1 1
MMP13 ATP6V1H 0 0 74 171 1 1
MMP13 SMAD9 0 0 137 204 1 1
MMP13 SIRT5 0 0 149 150 1 1
MMP13 ZFP64 0 0 415 414 1 1
MMP13 SP1 0 0 167 230 1 2
MMP13 IL1B 0 0 800 828 1 2
MMP13 MATN4 0 0 150 172 1 1
MMP13 ID1 0 0 211 212 1 1
MMP13 MAPK13 0 0 59 165 1 1
MMP13 CXCL8 0 0 602 619 1 2
MMP13 ADAMTS20 0 0 87 243 1 1
MMP13 WNT7A 0 0 206 221 1 1
MMP13 KLK3 0 0 153 152 1 1
MMP13 CTSL 0 500 261 615 1 2
MMP13 IL6R 0 0 193 196 1 1
MMP13 OPTC 0 900 86 911 1 1
MMP13 CTNNB1 0 0 556 578 1 2
MMP13 HRAS 0 0 218 271 1 2
MMP13 CDK2 0 0 151 150 1 2
MMP13 EGR1 0 0 283 282 1 2
MMP13 PLA2G4A 0 0 119 158 1 1
MMP13 MTSS1 0 0 125 153 1 1
MMP13 CXCR2 0 0 232 244 1 1
MMP13 WNT2B 0 0 151 257 1 1
MMP13 DDR2 0 0 504 512 1 1
MMP13 TNFRSF1B 0 0 151 169 1 1
MMP13 KRT17 0 0 157 193 1 1
MMP13 SAMSN1 0 0 0 187 1 1
MMP13 VAMP8 0 0 0 155 1 2
MMP13 JAK2 0 0 284 284 1 2
MMP13 WNT5B 0 0 241 266 1 1
MMP13 COL2A1 213 0 803 865 1 2
MMP13 CDH2 0 0 342 363 1 1
MMP13 HDAC6 0 0 137 162 1 2
MMP13 KIAA1324L 0 0 0 224 1 1
MMP13 SEMA3D 0 0 145 206 1 1
MMP13 BRD4 0 0 117 153 1 2
MMP13 ATP9B 0 0 157 156 1 1
MMP13 CHST11 0 0 228 229 1 1
MMP13 SLC9B2 0 0 115 190 1 1
MMP13 GGCX 0 0 91 151 1 1
MMP13 ADAMTS8 0 0 259 294 1 1
MMP13 ITGA5 0 0 260 276 1 1
MMP13 MMP15 0 0 602 173 1 1
MMP13 KRT5 0 0 143 174 1 1
MMP13 SERPINH1 0 0 286 297 1 1
MMP13 ANKH 0 0 263 263 1 1
MMP13 SOX4 0 0 154 170 1 1
MMP13 TBRG1 0 0 0 510 1 1
MMP13 PTN 0 0 141 162 1 1
MMP13 TGFA 0 0 216 216 1 1
MMP13 AGO2 0 0 167 167 1 2
MMP13 STAT3 0 0 455 455 1 2
MMP13 EZH2 0 0 141 161 1 2
MMP13 ADAM9 0 0 255 289 1 1
MMP13 ITGB8 0 0 117 166 1 1
MMP13 DKK2 0 0 181 181 1 1
MMP13 HTRA1 0 0 230 258 1 1
MMP13 HBEGF 0 0 283 296 1 1
MMP13 MDM2 0 0 183 183 1 2
MMP13 TP53 0 0 403 416 1 2
MMP13 LCN2 0 0 201 218 1 1
MMP13 DCN 0 0 659 674 1 2
MMP13 COL9A3 0 900 244 922 1 1
MMP13 FBLN2 0 0 113 193 1 1
MMP13 TGM2 0 0 254 271 1 2
MMP13 GMDS 0 0 0 334 1 1
MMP13 S100A1 0 0 150 174 1 1
MMP13 COL5A2 0 0 210 243 1 1
MMP13 FGFR3 0 0 390 390 1 1
MMP13 ESX1 0 0 398 398 1 1
MMP13 CDK4 0 0 143 175 1 2
MMP13 EGFR 0 0 341 366 1 2
MMP13 ECM1 0 0 167 200 1 1
MMP13 MYD88 0 0 283 298 1 2
MMP13 ADORA3 0 0 328 339 1 1
MMP13 IRAK1 0 0 218 218 1 1
MMP13 CSF3 0 0 287 302 1 1
MMP13 RAF1 0 0 96 160 1 2
MMP13 ADAMTS1 0 0 458 616 1 1
MMP13 FGF7 0 0 216 299 1 1
MMP13 PLOD1 0 0 325 325 1 1
MMP13 TRAF1 0 0 123 166 1 1
MMP13 HDAC2 0 0 217 218 1 1
MMP13 MAP3K7 0 0 171 171 1 2
MMP13 WNT4 0 0 234 260 1 1
MMP13 ADAMTS15 0 0 260 279 1 1
MMP13 LAMA4 0 0 170 169 1 1
MMP13 TNFRSF11B 0 0 505 519 1 1
MMP13 SMAD4 0 0 340 359 1 2
MMP13 LRP5 0 0 286 298 1 1
MMP13 SUCO 0 0 290 290 1 1
MMP13 EIF5B 0 0 304 304 1 1
MMP13 INHBA 0 0 134 175 1 1
MMP13 CTSE 0 0 141 199 1 1
MMP13 IL17RC 0 0 147 183 1 1
MMP13 CHI3L1 0 0 261 261 1 1
MMP13 ACTA1 0 0 125 212 1 1
MMP13 NFE2L2 0 0 166 165 1 2
MMP13 TLR1 0 0 150 208 1 1
MMP13 OGN 0 0 194 194 1 1
MMP13 PRSS3P2 0 0 180 179 1 1
MMP13 ACER3 0 0 0 424 1 1
MMP13 CTSV 0 300 48 305 1 1
MMP13 PDGFB 0 0 167 203 1 2
MMP13 BRCA1 0 0 95 151 1 2
MMP13 CD80 0 0 134 171 1 2
MMP13 KRT4 0 0 134 156 1 1
MMP13 FURIN 0 0 284 314 1 1
MMP13 AREG 0 0 189 206 1 1
MMP13 OSM 0 0 465 498 1 1
MMP13 MAP2K1 0 0 261 277 1 1
MMP13 F2RL1 0 0 134 166 1 1
MMP13 IL1R1 0 0 290 290 1 1
MMP13 MATN2 0 0 170 201 1 1
MMP13 IL15 0 0 234 250 1 1
MMP13 MYC 0 0 322 332 1 2
MMP13 LGMN 0 0 70 217 1 1
MMP13 PRSS23 0 0 86 177 1 1
MMP13 IFNA1 0 0 170 169 1 1
MMP13 WNT5A 0 0 370 391 1 2
MMP13 ILK 0 0 134 170 1 1
MMP13 PURA 0 0 57 150 1 1
MMP13 IL18 0 0 323 323 1 2
MMP13 IL36G 0 0 63 454 1 1
MMP13 MTF1 0 0 217 222 1 1
MMP13 IGF1R 0 0 261 261 1 2
MMP13 SDHC 0 0 257 256 1 1
MMP13 COL11A1 0 0 460 471 1 1
MMP13 TREM1 0 0 123 177 1 1
MMP13 PPARGC1A 0 0 148 167 1 2
MMP13 FGF10 0 0 141 334 1 1
MMP13 FGFBP1 0 0 128 156 1 1
MMP13 ADAM10 0 0 283 291 1 1
MMP13 HPSE 0 0 125 157 1 1
MMP13 NOG 0 0 232 231 1 1
MMP13 IBSP 0 0 564 575 1 1
MMP13 ATP6V1G1 0 0 90 182 1 1
MMP13 EGLN3 0 0 144 171 1 1
MMP13 ADORA1 0 0 325 336 1 1
MMP13 HYAL4 0 0 0 368 1 1
MMP13 HHIP 0 0 180 197 1 1
MMP13 MMP17 0 0 467 185 1 1
MMP13 ACP5 0 0 517 527 1 1
MMP13 SMAD7 0 0 324 340 1 1
MMP13 ITGAM 0 0 325 336 1 1
MMP13 P2RY2 0 0 49 307 1 1
MMP13 ESR1 0 0 335 335 1 2
MMP13 IFNB1 0 0 193 212 1 1
MMP13 HMGB1 0 0 323 338 1 2
MMP13 CTSK 0 300 672 766 1 2
MMP13 ADAMTS14 0 0 258 296 1 1
MMP13 LMNB1 0 0 143 182 1 1
MMP13 RGS2 0 0 108 640 1 1
MMP13 CTSB 0 300 338 527 1 2
MMP13 MCL1 0 0 150 168 1 2
MMP13 SIRT1 0 0 390 391 1 2
MMP13 ARHGEF17 0 0 45 541 1 1
MMP13 YAP1 0 0 155 154 1 2
MMP13 SOX6 0 0 418 432 1 1
MMP13 CXCR3 0 0 119 181 1 1
MMP13 IRF1 0 0 213 213 1 2
MMP13 ELN 0 0 557 596 1 1
MMP13 MT-ND1 0 0 0 248 1 1
MMP13 WNT3A 0 0 361 382 1 2
MMP13 MAP2K6 0 0 154 153 1 1
MMP13 ATG5 0 0 138 156 1 2
MMP13 ITGB3 0 0 218 255 1 1
MMP13 CLDN6 0 0 0 177 1 1
MMP13 MATN3 0 0 404 417 1 1
MMP13 TIMP2 0 0 921 976 1 1
MMP13 SERPINB5 0 0 167 180 1 1
MMP13 LAMA1 0 0 134 153 1 1
MMP13 MCAM 0 0 202 202 1 1
MMP13 SPHK1 0 0 134 152 1 2
MMP13 ADAM17 0 0 384 392 1 1
MMP13 TGFBR1 0 0 390 390 1 1
MMP13 S100A4 0 0 423 435 1 1
MMP13 ANXA6 0 0 124 155 1 1
MMP13 CLSTN2 0 0 232 231 1 1
MMP13 CMA1 0 0 171 172 1 1
MMP13 WISP3 0 0 150 180 1 1
MMP13 ADAM19 0 0 193 214 1 1
MMP13 GLI1 0 0 310 309 1 2
MMP13 CCR7 0 0 156 156 1 1
MMP13 GPX1 0 0 295 295 1 1
MMP13 TBP 0 0 155 205 1 1
MMP13 VTN 0 0 324 173 1 1
MMP13 FN1 0 0 633 665 1 2
MMP13 HABP2 0 0 150 232 1 1
MMP13 C3 0 0 124 161 1 2
MMP13 DEDD2 0 0 0 173 1 1
MMP13 ELANE 0 0 322 334 1 1
MMP13 ACVRL1 0 0 170 176 1 1
MMP13 SOX10 0 0 70 584 1 1
MMP13 KLK6 0 0 123 163 1 1
MMP13 TXNDC17 0 0 0 173 1 1
MMP13 ZNF609 0 0 108 255 1 1
MMP13 FGF12 0 0 0 248 1 1
MMP13 CTSG 0 0 216 223 1 1
MMP13 ENG 0 0 285 284 1 2
MMP13 CCL3 0 0 390 448 1 1
MMP13 CCL22 0 0 164 163 1 1
MMP13 AXIN1 0 0 170 169 1 1
MMP13 GUCY2D 0 0 0 319 1 1
MMP13 CTSD 0 0 246 269 1 2
MMP13 SERPINC1 0 0 74 230 1 1
MMP13 CYGB 0 0 74 161 1 1
MMP13 IGF2 0 0 213 213 1 1
MMP13 SMAD5 0 0 229 289 1 1
MMP13 SFRP1 0 0 234 234 1 1
MMP13 EFNB2 0 0 136 172 1 1
MMP13 CCL20 0 0 340 354 1 1
MMP13 IL10 0 0 508 534 1 2
MMP13 SNAI1 0 0 325 336 1 1
MMP13 FGFR4 0 0 185 195 1 1
MMP13 RBPJ 0 0 170 169 1 1
MMP13 SDC3 0 0 134 156 1 1
MMP13 COL1A1 0 0 681 699 1 2
MMP13 ITGB4 0 0 211 244 1 1
MMP13 CXCL2 0 0 369 425 1 1
MMP13 NAMPT 0 0 294 294 1 2
MMP13 CDH11 0 0 244 257 1 1
MMP13 FOSB 0 0 217 223 1 1
MMP13 WNT10A 0 0 184 200 1 1
MMP13 GDF5 0 0 517 517 1 1
MMP13 TJP1 0 0 157 171 1 1
MMP13 SELE 0 0 211 211 1 1
MMP13 TGFBR2 0 0 338 352 1 1
MMP13 TAC1 0 0 209 209 1 1
MMP13 ACTG1 0 0 213 262 1 1
MMP13 FOSL2 0 0 235 257 1 1
MMP13 GDF15 0 0 124 184 1 1
MMP13 ITGB5 0 0 157 192 1 1
MMP13 ADAMTS13 0 0 167 188 1 1
MMP13 GAPDHS 0 0 0 376 1 1
MMP13 MMP11 0 0 611 193 1 1
MMP13 PDCD1LG2 0 0 89 155 1 1
MMP13 LTB4R2 0 0 0 202 1 1
MMP13 NFATC1 0 0 322 321 1 2
MMP13 COL10A1 0 0 756 789 1 1
MMP13 PRELP 0 0 166 165 1 1
MMP13 TNFRSF11A 0 0 181 181 1 1
MMP13 KRT16 0 0 106 162 1 1
MMP13 VEGFA 0 0 637 640 1 2
MMP13 YARS 0 0 42 152 1 1
MMP13 PTEN 0 0 245 244 1 2
MMP13 MBP 0 0 54 193 1 2
MMP13 BMPR1A 0 0 218 219 1 1
MMP13 TIMP3 213 0 681 790 1 1
MMP13 MAPK14 0 0 320 432 1 2
MMP13 CSF3R 0 0 60 160 1 1
MMP13 PAX1 0 0 134 152 1 1
MMP13 RCHY1 0 0 0 173 1 1
MMP13 SREBF1 0 0 150 187 1 1
MMP13 NGFR 0 0 181 181 1 1
MMP13 NPPC 0 0 141 159 1 1
MMP13 PTH1R 0 0 408 418 1 1
MMP13 CCKBR 0 0 44 156 1 1
MMP13 ADAMTS7 0 0 325 346 1 1
MMP13 BMP4 0 0 370 370 1 1
MMP13 SYK 0 0 135 168 1 2
MMP13 LEP 0 0 395 394 1 1
MMP13 NFKBIA 0 0 500 499 1 2
MMP13 KIT 0 0 148 177 1 2
MMP13 ANGPTL2 0 0 108 153 1 1
MMP13 ALOX5 0 0 193 243 1 1
MMP13 IHH 0 0 668 688 1 1
MMP13 ACE 0 0 187 235 1 1
MMP13 CTSS 0 300 123 439 1 1
MMP13 FGF22 0 0 0 213 1 1
MMP13 IL13 0 0 371 371 1 2
MMP13 AFM 0 0 0 156 1 1
MMP13 REN 0 0 125 269 1 1
MMP13 KDELR3 0 0 136 154 1 1
MMP13 COL6A2 0 0 256 295 1 1
MMP13 MYT1 0 0 0 173 1 1
MMP13 CYBB 0 0 123 160 1 2
MMP13 VEGFC 0 0 243 242 1 1
MMP13 PPIA 0 0 158 159 1 1
MMP13 CXCL5 0 0 340 410 1 1
MMP13 CTSZ 0 0 138 172 1 1
MMP13 CXCL1 0 0 456 505 1 2
MMP13 IL33 0 0 245 244 1 2
MMP13 MMP14 213 900 754 931 1 1
MMP13 ELF3 0 0 256 261 1 1
MMP13 HDAC9 0 0 167 167 1 1
MMP13 NLRP3 0 0 218 235 1 2
MMP13 REL 0 0 181 181 1 2
MMP13 FIGF 0 0 122 154 1 1
MMP13 P2RY4 0 0 0 302 1 1
MMP13 IL1RL1 0 0 139 225 1 1
MMP13 ENPP1 0 0 260 260 1 1
MMP13 AFP 0 0 125 278 1 2
MMP13 CASP3 0 0 504 522 1 2
MMP13 F3 0 0 140 193 1 1
MMP13 PTGS2 0 0 616 636 1 2
MMP13 CCL11 0 0 212 230 1 1
MMP13 FGF19 0 0 0 245 1 1
MMP13 SMURF1 0 0 158 157 1 1
MMP13 ADAM28 0 0 211 289 1 1
MMP13 TWIST2 0 0 147 183 1 1
MMP13 CEBPB 0 0 339 361 1 2
MMP13 LAMB4 0 0 71 203 1 1
MMP13 FGF9 0 0 159 228 1 1
MMP13 FGF11 0 0 0 165 1 1
MMP13 WNT3 0 0 146 214 1 1
MMP13 RLN2 0 0 181 191 1 1
MMP13 COL9A2 0 900 289 927 1 1
MMP13 CSF1 0 0 326 341 1 1
MMP13 HDAC1 0 0 225 226 1 2
MMP13 GUSB 0 0 150 203 1 1
MMP13 FABP4 0 0 143 214 1 1
MMP13 BMPR1B 0 0 203 209 1 1
MMP13 MGP 0 0 245 282 1 1
MMP13 CDKN2A 0 0 294 294 1 2
MMP13 MRC1 0 0 260 507 1 1
MMP13 GSK3B 0 0 118 198 1 2
MMP13 ITGAX 0 0 166 185 1 1
MMP13 S100B 0 0 150 172 1 1
MMP13 FGF8 0 0 115 219 1 1
MMP13 ST14 0 0 122 155 1 1
MMP13 WNT2 0 0 202 393 1 1
MMP13 COL5A3 0 0 159 221 1 1
MMP13 S100A12 0 0 215 249 1 1
MMP13 TCN1 0 0 414 426 1 1
MMP13 HPX 0 0 468 264 1 1
MMP13 CHUK 0 0 300 300 1 1
MMP13 HSPA5 0 0 134 179 1 2
MMP13 CCL8 0 0 209 227 1 1
MMP13 CSRNP1 0 0 113 203 1 1
MMP13 SYNCRIP 0 0 0 189 1 1
MMP13 ITGB2 0 0 155 208 1 1
MMP13 EPAS1 0 0 310 383 1 2
MMP13 FOXO1 0 0 188 188 1 2
MMP13 KRAS 0 0 181 251 1 2
MMP13 SOD2 0 0 216 216 1 2
MMP13 CCL17 0 0 184 183 1 1
MMP13 PTH 0 0 518 548 1 1
MMP13 NKX3-2 0 0 268 268 1 1
MMP13 GDF6 0 0 186 186 1 1
MMP13 FASLG 0 0 157 156 1 1
MMP13 COL12A1 0 0 229 287 1 1
MMP13 FOS 0 0 464 468 1 2
MMP13 TWIST1 0 0 261 261 1 1
MMP13 S100A8 0 0 150 194 1 2
MMP13 SOCS3 0 0 269 285 1 1
MMP13 CA1 0 0 66 168 1 1
MMP13 DSC1 0 0 48 226 1 1
MMP13 ANGPTL4 0 0 157 182 1 1
MMP13 PROB1 0 0 97 153 1 1
MMP13 MMP24 0 0 469 153 1 1
MMP13 COL15A1 0 900 155 914 1 1
MMP13 CD86 0 0 152 171 1 1
MMP13 CILP2 0 0 103 286 1 1
MMP13 BGN 0 0 530 552 1 1
MMP13 DLX5 0 0 231 230 1 1
MMP13 COL9A1 0 900 452 944 1 1
MMP13 PGF 0 0 140 199 1 1
MMP13 CSPG4 0 0 125 216 1 1
MMP13 FOXC1 0 0 123 177 1 1
MMP13 CCL7 213 0 393 513 1 1
MMP13 BECN1 0 0 228 237 1 2
MMP13 PTGES 0 0 414 425 1 1
MMP13 THBS1 0 0 341 366 1 1
MMP13 SDC1 0 0 264 281 1 1
MMP13 TLR6 0 0 103 187 1 1
MMP13 LIM2 0 0 0 369 1 1
MMP13 IL2 0 0 279 279 1 1
MMP13 ANXA1 0 0 165 189 1 1
MMP13 ITGA2 0 0 255 254 1 1
MMP13 OLR1 0 0 140 176 1 2
MMP13 SFRP2 0 0 170 169 1 1
MMP13 LRP1 213 0 226 495 1 1
MMP13 MAPK11 0 0 113 191 1 1
MMP13 FLT4 0 0 135 189 1 1
MMP13 FGF23 0 0 260 341 1 1
MMP13 DUSP1 0 0 203 203 1 1
MMP13 BCAN 270 900 156 934 1 1
MMP13 TLR2 0 0 387 400 1 2
MMP13 EPYC 0 0 260 276 1 1
MMP13 MET 0 0 193 217 1 2
MMP13 CD4 0 0 315 320 1 2
MMP13 ATF4 0 0 193 193 1 2
MMP13 VCAM1 0 0 377 403 1 1
MMP13 COL19A1 0 0 46 161 1 1
MMP13 MEPE 0 0 261 279 1 1
MMP13 PTHLH 0 0 561 592 1 1
MMP13 LAMB3 0 900 235 920 1 1
MMP13 SUMO1 0 0 208 208 1 1
MMP13 CSF2 0 0 335 354 1 1
MMP13 FBN2 0 0 181 198 1 1
MMP13 IL17C 0 0 171 171 1 1
MMP13 MKI67 0 0 75 216 1 2
MMP13 AKT1 0 0 518 521 1 2
MMP13 TGFB2 0 0 424 424 1 1
MMP13 PPARG 0 0 395 400 1 2
MMP13 XIAP 0 0 143 178 1 2
MMP13 ZKSCAN7 0 0 411 410 1 1
MMP13 RUNX2 0 900 739 976 1 2
MMP13 COL4A3 0 0 134 183 1 1
MMP13 ING1 0 0 90 215 1 1
MMP13 FMOD 0 0 518 518 1 1
MMP13 NOX4 0 0 161 161 1 2
MMP13 RXFP1 0 0 216 251 1 1
MMP13 COL1A2 0 0 519 539 1 1
MMP13 GDF7 0 0 212 212 1 1
MMP13 ACE2 0 0 56 220 1 2
MMP13 IKBKB 0 0 268 268 1 2
MMP13 COL6A1 0 0 261 292 1 1
MMP13 KLF4 0 0 166 165 1 2
MMP13 FGFR1 0 0 294 294 1 1
MMP13 COL4A2 0 0 211 241 1 1
MMP13 CMC2 0 0 96 189 1 1
MMP13 CDH6 0 0 139 154 1 1
MMP13 MMP23B 0 0 379 182 1 1
MMP13 POLA1 0 0 67 263 1 1
MMP13 USP25 0 0 45 292 1 1
MMP13 CXCL10 0 0 370 385 1 2
MMP13 FGF3 0 0 106 243 1 1
MMP13 ITGB6 0 0 307 336 1 1
MMP13 SIRT4 0 0 158 159 1 1
MMP13 GJA1 0 0 161 171 1 1
MMP13 BTBD7 0 0 0 303 1 1
MMP13 GPT 0 0 260 266 1 1
MMP13 IL11 0 0 284 312 1 1
MMP13 PDE5A 0 0 91 186 1 1
MMP13 NID1 0 0 218 232 1 1
MMP13 KLK4 0 0 140 176 1 1
MMP13 CTSC 0 0 167 190 1 1
MMP13 CCL3L3 0 0 142 223 1 1
MMP13 DDR1 0 0 218 218 1 1
MMP13 NGF 0 0 323 323 1 2
MMP13 CD34 0 0 271 271 1 2
MMP13 ERBB2 0 0 266 294 1 2
MMP13 ARG2 0 0 184 198 1 1
MMP13 FBN1 0 0 242 290 1 1
MMP13 TLR9 0 0 272 272 1 2
MMP13 LTB4R 0 0 106 352 1 1
MMP13 TGFBI 0 0 243 344 1 1
MMP13 SMURF2 0 0 225 224 1 1
MMP13 CDC42 0 0 206 213 1 2
MMP13 F2 0 0 61 206 1 1
MMP13 SRC 0 0 323 356 1 2
MMP13 ADAM12 0 0 293 303 1 1
MMP13 DKK1 0 0 390 390 1 1
MMP13 ADAMTS17 0 0 140 167 1 1
MMP13 LRRC15 0 0 154 153 1 1
MMP13 CUTA 0 0 55 199 1 1
MMP13 APOE 0 0 260 301 1 2
MMP13 IL11RA 0 0 329 329 1 1
MMP13 CEMIP 0 0 123 183 1 1
MMP13 CBFB 0 900 45 905 1 1
MMP13 FOXO3 0 0 235 235 1 2
MMP13 IL36B 0 0 46 445 1 1
MMP13 ITGA6 0 0 193 193 1 1
MMP13 BGLAP 0 0 636 650 1 1
MMP13 ACTG2 0 0 86 177 1 1
MMP13 TNFSF11 0 0 611 643 1 2
MMP13 STAT6 0 0 157 156 1 1
MMP13 EIF2AK3 0 0 260 260 1 2
MMP13 HNF4A 0 0 235 235 1 1
MMP13 WWP2 0 0 157 158 1 1
MMP13 A2M 0 600 453 772 1 1
MMP13 ABLIM1 0 0 0 189 1 1
MMP13 FLT1 0 0 262 295 1 1
MMP13 TLR3 0 0 234 234 1 2
MMP13 LGALS3 0 0 271 310 1 2
MMP13 MIF 0 0 244 243 1 2
MMP13 CLDN4 0 0 61 313 1 1
MMP13 MMP12 0 300 754 377 1 1
MMP13 KDR 0 0 268 347 1 2
MMP13 DMP1 0 0 81 177 1 1
MMP13 RARRES2 0 0 176 175 1 1
MMP13 IL4I1 0 0 71 199 1 1
MMP13 JAK1 0 0 174 184 1 2
MMP13 HAS2 0 0 341 341 1 1
MMP13 HMMR 0 0 180 179 1 1
MMP13 NFATC2 0 0 216 216 1 1
MMP13 PPBP 0 0 157 222 1 1
MMP13 ASPN 0 0 262 266 1 1
MMP13 GOLM1 0 0 189 189 1 1
MMP13 ADIPOR2 0 0 160 159 1 1
MMP13 GLRX 0 0 49 307 1 1
MMP13 FOXP3 0 0 181 181 1 2
MMP13 HMOX1 0 0 321 347 1 2
MMP13 HYAL1 0 0 148 380 1 1
MMP13 LAMA3 0 900 180 914 1 1
MMP13 PRKCD 0 0 270 270 1 2
MMP13 MMP10 0 650 764 685 1 1
MMP13 LUM 0 0 401 414 1 1
MMP13 DSC3 0 0 55 168 1 1
MMP13 KRT19 0 0 166 165 1 1
MMP13 TGFB1 0 0 505 580 1 2
MMP13 ZNF384 0 0 283 282 1 1
MMP13 MSX2 0 0 182 181 1 1
MMP13 F2R 0 0 195 195 1 1
MMP13 PF4 0 0 150 190 1 1
MMP13 ALPL 0 0 405 405 1 1
MMP13 FGF16 0 0 0 227 1 1
MMP13 DOCK5 0 0 406 406 1 1
MMP13 SMAD6 0 0 218 232 1 1
MMP13 SCX 0 0 122 356 1 1
MMP13 HPRT1 0 0 250 256 1 1
MMP13 TRPS1 0 0 328 328 1 1
MMP13 LDLR 0 0 181 195 1 2
MMP13 COL7A1 0 0 330 343 1 1
MMP13 RUNX1 0 0 46 161 1 2
MMP13 COL6A3 0 0 181 225 1 1
MMP13 CCL1 0 0 150 241 1 1
MMP13 PECAM1 0 0 359 381 1 1
MMP13 CAT 0 0 260 260 1 2
MMP13 HPGD 0 0 170 169 1 1
MMP13 WNT10B 0 0 210 225 1 1
MMP13 ENSG00000264813 0 0 173 213 1 1
MMP13 LRP6 0 0 183 197 1 1
MMP13 FSTL1 0 0 151 150 1 1
MMP13 HGF 0 0 368 418 1 2
MMP13 BMP5 0 0 151 150 1 1
MMP13 GUCY2F 0 0 0 319 1 1
MMP13 MMP28 0 0 469 190 1 1
MMP13 POU5F1 0 0 181 183 1 2
MMP13 SLC39A8 0 0 432 432 1 1
MMP13 ADAMTS3 0 0 856 862 1 1
MMP13 HAPLN1 0 0 288 313 1 1
MMP13 BMPR2 0 0 167 167 1 1
MMP13 IRS1 0 0 124 156 1 2
MMP13 LOX 0 0 394 411 1 2
MMP13 MMP19 0 300 558 397 1 1
MMP13 EPOR 0 0 272 272 1 1
MMP13 EDNRA 0 0 145 159 1 1
MMP13 HMGCR 0 0 95 186 1 1
MMP13 NTRK1 0 0 170 169 1 1
MMP13 CYP24A1 0 0 137 160 1 1
MMP13 SPAM1 0 0 142 376 1 1
MMP13 PGR 0 0 155 318 1 1
MMP13 MUC1 0 0 143 161 1 1
MMP13 SERPINE1 0 0 457 526 1 1
MMP13 ADAMTS12 0 0 335 360 1 1
MMP13 RPS6KB1 0 0 170 188 1 2
MMP13 REM1 0 0 0 186 1 1
MMP13 FCGR1A 0 0 142 167 1 1
MMP13 ACTA2 0 0 126 390 1 1
MMP13 HDAC7 0 0 171 171 1 1
MMP13 DUSP18 0 0 67 165 1 1
MMP13 NOS3 0 0 235 235 1 2
MMP13 JUND 0 0 261 266 1 1
MMP13 GPR124 0 0 0 189 1 1
MMP13 CD274 0 0 134 171 1 2
MMP13 CCND1 0 0 375 382 1 2
MMP13 TNFRSF10D 0 0 306 306 1 1
MMP13 WNT8B 0 0 140 157 1 1
MMP13 FGF5 0 0 0 250 1 1
MMP13 WNT9A 0 0 234 249 1 1
MMP13 CD19 0 0 135 154 1 1
MMP13 FOXC2 0 0 90 184 1 1
MMP13 SERPINE2 0 0 134 279 1 1
MMP13 ANXA2 0 0 296 311 1 1
MMP13 GPNMB 0 0 194 212 1 1
MMP13 SFRP4 0 0 175 207 1 1
MMP13 CD9 0 0 155 154 1 1
MMP13 FGF2 0 0 520 539 1 2
MMP13 CXCL3 0 0 218 288 1 1
MMP13 S100A9 0 0 203 270 1 1
MMP13 RELB 0 0 170 177 1 2
MMP13 NFKB2 0 0 171 208 1 1
MMP13 AXIN2 0 0 285 284 1 1
MMP13 SRP54 0 0 0 192 1 1
MMP13 PTCH1 0 0 293 301 1 1
MMP13 IL5 0 0 229 228 1 1
MMP13 VWF 0 0 188 206 1 1
MMP13 CD63 0 0 154 153 1 2
MMP13 SOX5 0 0 458 467 1 1
MMP13 AGT 0 0 75 169 1 1
MMP13 IL1R2 0 0 155 155 1 1
MMP13 ENSG00000272980 0 0 124 373 1 1
MMP13 TNFAIP6 0 0 213 213 1 1
MMP13 PLOD2 0 0 143 180 1 1
MMP13 SOCS1 0 0 212 242 1 1
MMP13 THBS2 0 0 342 370 1 1
MMP13 IRF7 0 0 134 169 1 1
MMP13 MAPK1 0 0 175 181 1 2
MMP13 IGF1 0 0 518 531 1 2
MMP13 ITGA3 0 0 182 181 1 2
MMP13 CSF1R 0 0 184 183 1 1
MMP13 TNMD 0 0 425 453 1 1
MMP13 SHOX2 0 0 194 194 1 1
MMP13 CDH5 0 0 193 208 1 1
MMP13 RETN 0 0 261 261 1 1
MMP13 SDC4 0 0 370 423 1 1
MMP13 ATF3 0 0 236 258 1 2
MMP13 GADD45A 0 0 143 179 1 1
MMP13 EPHB4 0 0 146 165 1 1
MMP13 NR4A2 0 0 149 202 1 1
MMP13 VDR 0 0 243 242 1 2
MMP13 WISP1 0 0 282 282 1 1
MMP13 DKK3 0 0 170 169 1 1
MMP13 IL1RN 0 0 372 397 1 1
MMP13 MMP3 0 300 875 373 1 1
MMP13 IL7 0 0 194 194 1 1
MMP13 ADAMTS4 0 0 856 872 1 1
MMP13 KRT14 0 0 189 189 1 1
MMP13 NT5E 0 0 230 229 1 1
MMP13 MMP25 0 0 469 202 1 1
MMP13 MEF2C 0 0 244 243 1 1
MMP13 CD44 0 0 459 474 1 2
MMP13 ANKRD1 0 0 161 161 1 1
MMP13 BDNF 0 0 142 175 1 2
MMP13 HSPA13 0 0 52 575 1 1
MMP13 COL8A1 0 0 213 251 1 1
MMP13 TNF 0 0 686 721 1 2
MMP13 NOV 0 0 208 208 1 1
MMP13 PLA2G2A 0 0 113 152 1 1
MMP13 ADAMTS9 0 0 271 318 1 1
MMP13 PDGFC 0 0 123 299 1 1
MMP13 CNOT8 0 0 0 162 1 1
MMP13 NFAT5 0 0 150 174 1 1
MMP13 GPC1 0 0 129 155 1 1
MMP13 MMP7 0 300 739 352 1 1
MMP13 RCAN1 0 0 125 270 1 2
MMP13 VCL 0 0 195 195 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0005509 Molecular Function calcium ion binding enables IDA
GO:0005518 Molecular Function collagen binding enables IDA
GO:0004175 Molecular Function endopeptidase activity enables IDA
GO:0004222 Molecular Function metalloendopeptidase activity enables IBA
GO:0004222 Molecular Function metalloendopeptidase activity enables IDA
GO:0004222 Molecular Function metalloendopeptidase activity enables TAS
GO:0004252 Molecular Function serine-type endopeptidase activity enables TAS
GO:0008270 Molecular Function zinc ion binding enables IDA
GO:0030282 Biological Process bone mineralization involved_in IEA
GO:0060349 Biological Process bone morphogenesis involved_in IDA
GO:0030574 Biological Process collagen catabolic process involved_in IBA
GO:0030574 Biological Process collagen catabolic process involved_in IDA
GO:0030574 Biological Process collagen catabolic process involved_in TAS
GO:0001958 Biological Process endochondral ossification involved_in IEA
GO:0022617 Biological Process extracellular matrix disassembly involved_in IMP
GO:0022617 Biological Process extracellular matrix disassembly involved_in TAS
GO:0030198 Biological Process extracellular matrix organization involved_in IBA
GO:0003417 Biological Process growth plate cartilage development involved_in IEA
GO:0006508 Biological Process proteolysis involved_in IEA
GO:1904645 Biological Process response to amyloid-beta involved_in TAS
GO:0031012 Cellular Component extracellular matrix located_in IEA
GO:0005576 Cellular Component extracellular region located_in TAS
GO:0005615 Cellular Component extracellular space is_active_in IBA
Pathways
Name DB ID
Collagen degradation Reactome R-HSA-1442490
Degradation of the extracellular matrix Reactome R-HSA-1474228
Extracellular matrix organization Reactome R-HSA-1474244
Collagen formation Reactome R-HSA-1474290
Activation of Matrix Metalloproteinases Reactome R-HSA-1592389
Assembly of collagen fibrils and other multimeric structures Reactome R-HSA-2022090
Generic Transcription Pathway Reactome R-HSA-212436
RNA Polymerase II Transcription Reactome R-HSA-73857
Gene expression (Transcription) Reactome R-HSA-74160
Transcriptional regulation by RUNX2 Reactome R-HSA-8878166
RUNX2 regulates genes involved in cell migration Reactome R-HSA-8941332
Oncostatin M signaling pathway (WP2374) WikiPathways WP2374_r120781
Chronic hyperglycemia impairment of neuron function (WP5283) WikiPathways WP5283_r124551
Matrix metalloproteinases (WP129) WikiPathways WP129_r117774
Endochondral ossification with skeletal dysplasias (WP4808) WikiPathways WP4808_r117708
Burn wound healing (WP5055) WikiPathways WP5055_r122621
IL-18 signaling pathway (WP4754) WikiPathways WP4754_r115147
Endochondral ossification (WP474) WikiPathways WP474_r117098
AGE/RAGE pathway (WP2324) WikiPathways WP2324_r120674
Transcripts
Accession Version MolecularType Name NCBI Comments
NM_002427 4 mRNA None NC_000011 Reference