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MPG

N-methylpurine DNA glycosylase
General Information
Name N-methylpurine DNA glycosylase
Alias
  • DNA-3-methyladenine glycosylase
  • 3' end of the Mid1 gene, localized 68 kb upstream the humanzeta globin gene on 16p
  • 3-alkyladenine DNA glycosylase
  • 3-methyladenine DNA glycosidase
  • CRA36.1 (3-methyl-adenine DNA glycosylase)
  • N-methylpurine-DNA glycosylase, MPG
  • proliferation-inducing protein 11
  • proliferation-inducing protein 16
Gene_family DNA glycosylases
organism Homo sapiens
entrez_id 4350
location 16p13.3
transcript_count 3
exon_count 6
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez Predicted to enable alkylbase DNA N-glycosylase activity. Predicted to be involved in base-excision repair. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
    Stringdb DNA-3-methyladenine glycosylase; Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions
    nextProt Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
MPG BioGRID S GeneID BioGRID Proximity Label-MS
MPG BioGRID S GeneID BioGRID Proximity Label-MS
MPG BioGRID ACE2 GeneID BioGRID Proximity Label-MS
MPG BioGRID TGOLN2 GeneID BioGRID Proximity Label-MS
MPG BioGRID UBE2O GeneID BioGRID Affinity Capture-MS
MPG BioGRID TNIP1 GeneID BioGRID Affinity Capture-MS
MPG BioGRID TRIM67 GeneID BioGRID Affinity Capture-MS
MPG BioGRID H3C3 GeneID BioGRID Proximity Label-MS
MPG BioGRID TP53 GeneID BioGRID Affinity Capture-MS
MPG BioGRID ZRANB1 GeneID BioGRID Affinity Capture-MS
MPG BioGRID BRD3 GeneID BioGRID Affinity Capture-MS
MPG BioGRID GHITM GeneID BioGRID Affinity Capture-MS
MPG BioGRID ELP1 GeneID BioGRID Affinity Capture-MS
MPG BioGRID USP7 GeneID BioGRID Affinity Capture-MS
MPG BioGRID MAP4K2 GeneID BioGRID Affinity Capture-MS
MPG BioGRID KBTBD4 GeneID BioGRID Affinity Capture-MS
MPG BioGRID ELP2 GeneID BioGRID Affinity Capture-MS
MPG BioGRID ELP3 GeneID BioGRID Affinity Capture-MS
MPG BioGRID CIC GeneID BioGRID Affinity Capture-MS
MPG BioGRID GPR182 GeneID BioGRID Two-hybrid
MPG BioGRID KIF14 GeneID BioGRID Affinity Capture-MS
MPG BioGRID HSPD1 GeneID BioGRID Proximity Label-MS
MPG BioGRID ESR1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
MPG BioGRID MLH1 GeneID BioGRID Two-hybrid
MPG BioGRID Hsp22 GeneID BioGRID Affinity Capture-MS
MPG BioGRID H4C1 GeneID BioGRID Affinity Capture-MS
MPG BioGRID H2AC4 GeneID BioGRID Affinity Capture-MS
MPG BioGRID MYC GeneID BioGRID Affinity Capture-MS
MPG BioGRID HEXIM1 GeneID BioGRID Affinity Capture-MS
MPG BioGRID ESR2 GeneID BioGRID Affinity Capture-MS
MPG BioGRID HSD17B14 GeneID BioGRID Two-hybrid
MPG BioGRID FBXO7 GeneID BioGRID Biochemical Activity
MPG BioGRID OTUB1 GeneID BioGRID Affinity Capture-MS
MPG BioGRID Rrbp1 GeneID BioGRID Affinity Capture-MS
MPG BioGRID Srp72 GeneID BioGRID Affinity Capture-MS
MPG BioGRID Rpl35 GeneID BioGRID Affinity Capture-MS
MPG BioGRID Eif3a GeneID BioGRID Affinity Capture-MS
MPG BioGRID H2BC8 GeneID BioGRID Proximity Label-MS
MPG BioGRID RPL10 GeneID BioGRID Affinity Capture-MS
MPG BioGRID NPM1 GeneID BioGRID Affinity Capture-MS
MPG BioGRID CRK GeneID BioGRID Two-hybrid
MPG BioGRID EIF2A GeneID BioGRID Co-fractionation
MPG BioGRID KIFC1 GeneID BioGRID Co-fractionation
MPG BioGRID RPA3 GeneID BioGRID Affinity Capture-MS
MPG BioGRID RPA2 GeneID BioGRID Affinity Capture-MS
MPG BioGRID RPA1 GeneID BioGRID Affinity Capture-MS
MPG BioGRID HECW2 GeneID BioGRID Affinity Capture-MS
MPG BioGRID UHRF2 GeneID BioGRID Affinity Capture-Western
MPG BioGRID LARP4 GeneID BioGRID Affinity Capture-MS
MPG BioGRID OBSCN GeneID BioGRID Affinity Capture-MS
MPG BioGRID DHX33 GeneID BioGRID Affinity Capture-MS
MPG BioGRID PRPF38B GeneID BioGRID Affinity Capture-MS
MPG BioGRID GNL2 GeneID BioGRID Affinity Capture-MS
MPG BioGRID UHRF1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
MPG BioGRID RACGAP1 GeneID BioGRID Affinity Capture-MS
MPG BioGRID RRP7A GeneID BioGRID Affinity Capture-MS
MPG BioGRID GNL3 GeneID BioGRID Affinity Capture-MS
MPG BioGRID NOC2L GeneID BioGRID Affinity Capture-MS
MPG BioGRID TFIP11 GeneID BioGRID Affinity Capture-MS
MPG BioGRID RPRD2 GeneID BioGRID Affinity Capture-MS
MPG BioGRID CLASP2 GeneID BioGRID Affinity Capture-MS
MPG BioGRID RRP1B GeneID BioGRID Affinity Capture-MS
MPG BioGRID KDM2A GeneID BioGRID Affinity Capture-MS
MPG BioGRID MORF4L1 GeneID BioGRID Affinity Capture-MS
MPG BioGRID FXR2 GeneID BioGRID Affinity Capture-MS
MPG BioGRID SART1 GeneID BioGRID Affinity Capture-MS
MPG BioGRID KHSRP GeneID BioGRID Affinity Capture-MS
MPG BioGRID SRSF1 GeneID BioGRID Affinity Capture-MS
MPG BioGRID RFC4 GeneID BioGRID Affinity Capture-MS
MPG BioGRID PPP1R10 GeneID BioGRID Affinity Capture-MS
MPG BioGRID EXOSC9 GeneID BioGRID Affinity Capture-MS
MPG BioGRID PKM GeneID BioGRID Affinity Capture-MS
MPG BioGRID PRDX1 GeneID BioGRID Affinity Capture-MS
MPG BioGRID NCBP1 GeneID BioGRID Affinity Capture-MS
MPG BioGRID LHCGR GeneID BioGRID Affinity Capture-MS
MPG BioGRID GSN GeneID BioGRID Affinity Capture-MS
MPG BioGRID FLG GeneID BioGRID Affinity Capture-MS
MPG BioGRID KPRP GeneID BioGRID Affinity Capture-MS
MPG BioGRID POLR1F GeneID BioGRID Affinity Capture-MS
MPG BioGRID SERPINA12 GeneID BioGRID Affinity Capture-MS
MPG BioGRID CSTF1 GeneID BioGRID Affinity Capture-MS
MPG BioGRID CST6 GeneID BioGRID Affinity Capture-MS
MPG BioGRID CDSN GeneID BioGRID Affinity Capture-MS
MPG BioGRID CAPZA1 GeneID BioGRID Affinity Capture-MS
MPG BioGRID rev GeneID BioGRID Affinity Capture-MS
MPG BioGRID MDC1 GeneID BioGRID Affinity Capture-MS
MPG BioGRID APP GeneID BioGRID Reconstituted Complex
MPG BioGRID PRNP GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
MPG BioGRID TERF2IP GeneID BioGRID Two-hybrid
MPG BioGRID RAD23A GeneID BioGRID Reconstituted Complex; Two-hybrid
MPG BioGRID HDGF GeneID BioGRID Affinity Capture-MS
MPG Protein THRB GeneID HPRD
MPG Protein RAD23A GeneID HPRD
MPG Protein RAD23B GeneID HPRD
MPG Protein EP300 GeneID HPRD
MPG Protein RXRA GeneID HPRD
MPG Protein ESR1 GeneID HPRD
MPG BioGRID LRRC59 GeneID BioGRID Affinity Capture-MS
MPG BioGRID RANBP1 GeneID BioGRID Affinity Capture-MS
MPG BioGRID GSTM3 GeneID BioGRID Affinity Capture-MS
MPG BioGRID GOT2 GeneID BioGRID Affinity Capture-MS
MPG BioGRID FBLN1 GeneID BioGRID Affinity Capture-MS
MPG Protein ESR1 GeneID BIND ESR1 (ER-alpha) interacts with MPG.
MPG Protein RXRA GeneID BIND MPG interacts with RXRA (RXR-alpha). This interaction was modeled on a demonstrated interaction between MPG from an unspecified species and RXRA from an unspecified species.
MPG Protein PPARG GeneID BIND MPG interacts with an unspecified isoform of PPARG (PPAR-gamma). This interaction was modeled on a demonstrated interaction between MPG from an unspecified species and PPARG from an unspecified species.
MPG Protein THRB GeneID BIND MPG interacts with THRB (TR-beta). This interaction was modeled on a demonstrated interaction between MPG from an unspecified species and THRB from an unspecified species.
MPG Protein EP300 GeneID BIND EP300 (p300) acetylates MPG. This interaction was modeled on a demonstrated interaction between EP300 from an unspecified species and MPG from an unspecified species.
StringDB
A B experiments database textmining combined score hadb nhadb
MPG POLR1B 0 0 77 192 1 1
MPG DCTD 0 0 150 344 1 1
MPG NUDT15 0 0 47 223 1 1
MPG GABPA 0 0 0 152 1 1
MPG GOLT1A 0 0 0 234 1 1
MPG DARS2 0 0 0 190 1 1
MPG UGT8 0 0 194 195 1 1
MPG MCMDC2 0 0 0 189 1 1
MPG EPHA2 0 0 146 178 1 1
MPG MSH6 0 0 324 380 1 1
MPG C9orf142 0 0 0 155 1 1
MPG LIAS 0 0 0 187 1 1
MPG LACC1 0 0 0 200 1 1
MPG POLH 0 0 122 206 1 1
MPG GOLT1B 0 0 0 234 1 1
MPG GCA 0 0 261 261 1 1
MPG NOC2L 270 0 0 288 1 1
MPG DOHH 0 0 49 352 1 1
MPG HIST1H4F 270 0 0 270 1 1
MPG APEX2 0 0 289 360 1 1
MPG CDSN 270 0 0 270 1 1
MPG GNE 0 0 0 177 1 1
MPG CARS 0 0 0 267 1 1
MPG RAD23A 270 0 57 336 1 1
MPG RAD51 0 0 261 261 1 2
MPG FARSA 0 0 0 205 1 1
MPG MYOG 0 0 482 482 1 1
MPG ATRIP 0 0 193 193 1 1
MPG ELAVL3 0 0 0 290 1 1
MPG AQP8 0 0 74 446 1 1
MPG ART1 0 0 151 150 1 1
MPG DOCK7 0 0 0 209 1 1
MPG POLE 0 0 0 165 1 1
MPG PNPO 0 0 0 254 1 1
MPG TOP3B 0 0 0 157 1 1
MPG MGMT 0 0 612 781 1 2
MPG POLK 0 0 103 189 1 1
MPG TFB1M 0 0 0 171 1 1
MPG SLX1A 0 0 193 251 1 1
MPG WRNIP1 0 0 0 160 1 1
MPG DERA 0 0 0 275 1 1
MPG XPA 0 0 391 528 1 1
MPG UHRF1 270 0 432 567 1 1
MPG HDGF 270 0 0 270 1 1
MPG NDUFV2 0 0 0 295 1 1
MPG GAPDH 0 0 123 210 1 2
MPG TM7SF2 0 0 0 191 1 1
MPG APTX 0 0 284 360 1 1
MPG NMNAT1 0 0 0 245 1 1
MPG CAPZA1 285 0 0 284 1 1
MPG ATRX 0 0 156 171 1 1
MPG BCDIN3D 0 0 154 153 1 1
MPG APEX1 0 650 710 904 1 1
MPG IKBKAP 489 0 0 489 1 1
MPG POLL 0 0 391 480 1 1
MPG VARS2 0 0 0 260 1 1
MPG OBSCN 270 0 0 270 1 1
MPG MLH3 0 0 210 306 1 1
MPG DHX33 270 0 0 286 1 1
MPG GLS 0 0 181 183 1 2
MPG LBR 0 0 0 392 1 1
MPG POLM 0 0 388 468 1 1
MPG TOP1 0 0 207 400 1 1
MPG PIGF 0 0 0 642 1 1
MPG TMEM19 0 0 0 245 1 1
MPG KIFC1 272 0 0 283 1 1
MPG FARS2 0 0 0 189 1 1
MPG CACNA1S 0 0 642 642 1 1
MPG RPRD2 270 0 0 274 1 1
MPG FXN 0 0 93 210 1 1
MPG PARK7 0 0 0 225 1 2
MPG XRCC3 0 0 147 183 1 1
MPG IYD 0 0 0 261 1 1
MPG CALCOCO1 0 0 166 165 1 1
MPG REV1 0 0 233 306 1 1
MPG ST13 0 0 157 178 1 2
MPG OPA1 0 0 227 696 1 2
MPG BRCA1 0 0 207 207 1 2
MPG ENDOV 0 0 651 651 1 1
MPG HIST1H2AE 270 0 0 270 1 1
MPG TALDO1 0 0 0 392 1 1
MPG TP53 0 0 269 269 1 2
MPG ERCC2 0 0 244 264 1 1
MPG CGA 0 0 228 227 1 2
MPG EGFR 0 0 139 160 1 2
MPG AADAT 0 0 120 216 1 1
MPG RNASEH2A 0 0 0 184 1 1
MPG GNL3 270 0 0 285 1 1
MPG ENSG00000203546 0 0 0 177 1 1
MPG SLC9A3R2 0 0 88 156 1 1
MPG ZNF248 0 0 242 241 1 1
MPG EXO1 0 0 181 219 1 1
MPG LMF1 0 0 137 188 1 1
MPG NME3 0 0 0 373 1 1
MPG SLURP1 0 0 113 200 1 1
MPG POLR3B 0 0 90 159 1 1
MPG APRT 0 0 0 290 1 1
MPG ALKBH3 0 0 560 568 1 1
MPG HDDC3 0 0 0 252 1 1
MPG GSTK1 0 0 96 152 1 1
MPG POGZ 0 0 0 179 1 1
MPG SRSF1 270 0 0 285 1 1
MPG ELAVL2 0 0 0 539 1 1
MPG PLEKHG5 0 0 0 258 1 1
MPG XRCC6 0 0 181 186 1 1
MPG PIGN 0 0 52 151 1 1
MPG NCOA1 0 900 54 901 1 1
MPG ARSB 0 0 139 509 1 2
MPG ALB 0 0 166 165 1 2
MPG MCM4 0 0 454 496 1 1
MPG PITPNM1 0 0 142 163 1 1
MPG ELAVL1 0 0 0 422 1 2
MPG TWISTNB 270 0 0 270 1 1
MPG PIGV 0 0 55 157 1 1
MPG LIG3 0 0 519 576 1 1
MPG EP300 213 900 54 920 1 2
MPG LRRC47 0 0 0 316 1 1
MPG ASL 0 0 0 236 1 1
MPG DUT 0 0 211 211 1 1
MPG PDPN 0 0 138 170 1 1
MPG IDH1 0 0 166 165 1 1
MPG XRCC4 0 0 289 288 1 1
MPG ALKBH2 0 0 661 668 1 1
MPG NMNAT2 0 0 0 220 1 1
MPG ERCC4 0 0 112 153 1 1
MPG ART3 0 0 0 187 1 1
MPG H2AFX 0 0 215 254 1 1
MPG VPS18 0 0 827 827 1 1
MPG ENSG00000249319 0 0 0 219 1 1
MPG KDM2A 270 0 0 281 1 1
MPG HBZ 0 0 764 764 1 1
MPG OTUB1 270 0 0 270 1 1
MPG MT-ND6 0 0 112 173 1 1
MPG PRNP 270 0 396 554 1 2
MPG FLG 270 0 0 270 1 1
MPG PPP1R10 270 0 0 284 1 1
MPG NMNAT3 0 0 0 303 1 1
MPG XRCC1 270 0 603 727 1 1
MPG PMS1 0 0 155 257 1 1
MPG CHEK2 0 0 141 200 1 1
MPG OGG1 0 0 755 862 1 1
MPG NACC1 0 0 0 205 1 1
MPG DOCK11 0 0 246 293 1 1
MPG CD59 0 0 0 189 1 1
MPG TMEM176B 0 0 128 218 1 1
MPG MRPL20 0 0 0 245 1 1
MPG PUS1 0 0 0 175 1 1
MPG TAT 0 0 210 239 1 2
MPG TDP1 0 0 294 416 1 1
MPG RAD17 0 0 150 212 1 1
MPG FBXO7 270 0 0 295 1 1
MPG VARS 0 0 0 277 1 1
MPG DIS3L2 0 0 0 191 1 1
MPG NTHL1 0 0 666 791 1 1
MPG JUN 129 0 72 157 1 2
MPG DIS3L 0 0 0 185 1 1
MPG MALSU1 0 0 0 295 1 1
MPG ARSI 0 0 0 189 1 1
MPG NEIL2 0 0 561 752 1 1
MPG DNTT 0 0 60 183 1 1
MPG MVP 0 0 134 154 1 1
MPG TFIP11 270 0 0 285 1 1
MPG EXOSC9 270 0 0 323 1 1
MPG CLIP4 0 0 362 362 1 1
MPG SLC7A9 0 0 0 210 1 1
MPG UHRF2 270 0 104 317 1 1
MPG SLC7A10 0 0 0 211 1 1
MPG CRK 170 0 0 169 1 1
MPG NEMF 0 0 0 188 1 1
MPG NEIL1 0 0 681 873 1 1
MPG NCBP1 270 0 0 325 1 1
MPG XPC 0 0 233 301 1 1
MPG ELP3 294 0 0 294 1 1
MPG PRDX1 270 0 49 321 1 1
MPG NPRL3 0 0 260 368 1 1
MPG MED12 0 0 0 154 1 1
MPG DNA2 0 0 124 163 1 1
MPG FEN1 0 0 460 527 1 1
MPG SART1 270 0 0 331 1 1
MPG UMPS 0 0 0 311 1 1
MPG GTF3C1 0 0 0 155 1 1
MPG GNL2 270 0 0 289 1 1
MPG ADORA2A 0 0 0 248 1 1
MPG RHBDF2 0 0 0 283 1 1
MPG OAT 0 0 0 295 1 1
MPG PARP1 0 0 422 422 1 2
MPG GSN 270 0 0 270 1 1
MPG CLASP2 270 0 0 279 1 1
MPG SERPINA12 270 0 0 272 1 1
MPG KBTBD4 496 0 0 495 1 1
MPG ENSG00000258555 0 0 0 248 1 1
MPG CSTF1 270 0 0 270 1 1
MPG ACR 0 0 112 201 1 1
MPG SLC30A9 0 0 0 197 1 1
MPG DTD2 0 0 0 177 1 1
MPG GRASP 0 0 0 303 1 1
MPG KHSRP 270 0 0 305 1 1
MPG SETDB1 0 0 0 159 1 1
MPG LPPR2 0 0 0 173 1 1
MPG TMEM176A 0 0 150 281 1 1
MPG FDX1L 0 0 0 226 1 1
MPG WRN 0 0 211 281 1 1
MPG TMEM8A 0 0 184 428 1 1
MPG KDM1B 0 0 0 211 1 1
MPG RFC4 270 0 0 303 1 1
MPG ASS1 0 0 0 295 1 1
MPG INPP5J 0 0 48 153 1 1
MPG RRP1B 270 0 0 280 1 1
MPG PUS3 0 0 0 175 1 1
MPG HEXIM1 270 0 0 295 1 1
MPG POLRMT 0 0 0 239 1 1
MPG CDA 0 0 134 173 1 1
MPG CTCF 0 0 0 156 1 1
MPG ADORA2B 0 0 0 248 1 1
MPG DSC3 0 0 397 397 1 1
MPG DIS3 0 0 0 185 1 1
MPG ADA 0 0 96 158 1 1
MPG RNASEH1 0 0 0 167 1 1
MPG CCNO 0 0 134 369 1 1
MPG PAPD7 0 0 184 442 1 1
MPG POLB 0 0 603 677 1 1
MPG RHBDF1 0 0 248 572 1 1
MPG TERF2IP 295 0 0 325 1 1
MPG HDHD1 0 0 0 216 1 1
MPG PAPD5 0 0 0 228 1 1
MPG PIGB 0 0 66 219 1 1
MPG MVD 0 0 0 173 1 1
MPG DTD1 0 0 0 177 1 1
MPG CST6 270 0 0 270 1 1
MPG FDX1 0 0 0 226 1 1
MPG PMS2 0 0 226 341 1 1
MPG TRMU 0 0 0 231 1 1
MPG XAB2 0 0 0 162 1 1
MPG FANCD2 0 0 151 187 1 1
MPG NEIL3 0 0 460 586 1 1
MPG CCDC101 0 0 150 183 1 1
MPG TOP1MT 0 0 47 450 1 1
MPG ENSG00000255767 0 0 0 167 1 1
MPG MRPL33 0 0 0 173 1 1
MPG ALKBH8 0 0 321 350 1 1
MPG PIGH 0 0 63 210 1 1
MPG PUSL1 0 0 0 205 1 1
MPG ABCG8 0 0 61 169 1 1
MPG CARS2 0 0 0 251 1 1
MPG FXR2 270 0 0 279 1 1
MPG GGPS1 0 0 75 161 1 1
MPG SCP2 0 0 167 167 1 1
MPG TDG 0 0 652 681 1 1
MPG GTF3C5 0 0 0 188 1 1
MPG ELP2 481 0 48 484 1 1
MPG LIG4 0 0 205 251 1 1
MPG KYNU 0 0 0 285 1 1
MPG SLC7A11 0 0 0 216 1 2
MPG PIGX 0 0 0 189 1 1
MPG MUTYH 0 0 561 739 1 1
MPG ERCC3 0 0 235 353 1 1
MPG LEO1 0 0 0 158 1 1
MPG ALDH18A1 0 0 0 327 1 1
MPG MRPL28 0 0 293 509 1 1
MPG GEN1 0 0 93 186 1 1
MPG SSU72 0 0 113 155 1 1
MPG DOCK6 0 0 122 275 1 1
MPG PRPF38B 270 0 0 292 1 1
MPG GLTSCR2 0 0 172 220 1 1
MPG PARP3 0 0 81 150 1 1
MPG SLC38A3 0 0 393 392 1 1
MPG PKM 270 0 0 311 1 1
MPG SCN4A 0 0 323 323 1 1
MPG ITPA 0 0 266 338 1 1
MPG PGC 0 0 677 679 1 1
MPG PRKDC 0 0 218 218 1 2
MPG ALDH2 0 0 0 179 1 2
MPG FARSB 0 0 53 382 1 1
MPG PDLIM7 0 0 0 238 1 1
MPG HPRT1 0 0 538 538 1 1
MPG MAD2L2 0 0 174 194 1 1
MPG MT-ND5 0 0 66 214 1 1
MPG CAT 0 0 95 245 1 2
MPG IDE 0 0 0 193 1 1
MPG ARHGAP25 0 0 161 306 1 1
MPG HELZ2 0 0 0 232 1 1
MPG NHEJ1 0 0 194 194 1 1
MPG SLX1B 0 0 193 251 1 1
MPG KIF14 270 0 0 270 1 1
MPG AASDHPPT 0 0 0 225 1 1
MPG NUDT1 0 0 324 389 1 1
MPG SLC7A7 0 0 0 201 1 1
MPG HECW2 270 0 0 276 1 1
MPG YARS 0 0 0 346 1 1
MPG FDXACB1 0 0 0 185 1 1
MPG YARS2 0 0 0 225 1 1
MPG FAM173A 0 0 0 175 1 1
MPG DIMT1 0 0 0 337 1 1
MPG HFE 0 0 66 163 1 1
MPG MSH3 0 0 283 332 1 1
MPG POLI 0 0 194 271 1 1
MPG ICT1 0 0 0 273 1 1
MPG PNKP 0 0 414 459 1 1
MPG LHCGR 270 0 0 270 1 1
MPG ARSJ 0 0 0 189 1 1
MPG RAD23B 213 0 205 385 1 1
MPG UNG 0 0 653 705 1 1
MPG REV3L 0 0 155 174 1 1
MPG ATM 0 0 234 234 1 2
MPG NUDT16 0 0 294 315 1 1
MPG NDUFS2 0 0 0 187 1 1
MPG ADARB1 0 0 56 201 1 1
MPG NPM1 235 0 0 250 1 1
MPG SCRG1 0 0 161 305 1 1
MPG ORC5 0 0 0 153 1 1
MPG RECQL4 0 0 66 306 1 1
MPG MCM8 0 0 0 189 1 1
MPG LPPR5 0 0 204 402 1 1
MPG PIGA 0 0 108 358 1 1
MPG EIF2A 272 0 0 293 1 2
MPG PYURF 0 0 0 302 1 1
MPG URGCP 0 0 180 179 1 1
MPG COQ3 0 0 0 216 1 1
MPG RAD52 0 0 260 260 1 1
MPG EIF4G2 0 0 155 173 1 1
MPG PKN3 0 0 134 160 1 1
MPG LIG1 0 0 530 553 1 1
MPG PIGQ 0 0 167 328 1 1
MPG HMGB1 0 0 108 166 1 2
MPG NAGS 0 0 0 295 1 1
MPG ESR1 295 900 96 930 1 2
MPG MSH2 0 0 323 375 1 1
MPG INPP5K 0 0 0 213 1 1
MPG DSG1 0 0 477 477 1 1
MPG LARP4 270 0 0 305 1 1
MPG NRD1 0 0 0 189 1 1
MPG SRRM1 0 0 100 154 1 1
MPG TMEM8B 0 0 0 302 1 1
MPG GBE1 0 0 0 150 1 1
MPG ERCC6 0 0 250 250 1 1
MPG TMX2 0 0 166 165 1 1
MPG PARP2 0 0 242 247 1 1
MPG SELO 0 0 0 242 1 1
MPG DNAJB9 0 0 419 423 1 2
MPG NELFA 0 0 0 152 1 1
MPG SLC25A15 0 0 324 323 1 1
MPG NIF3L1 0 0 0 288 1 1
MPG PES1 0 0 0 155 1 1
MPG POLR3K 0 0 155 173 1 1
MPG ELAVL4 0 0 0 208 1 1
MPG MLH1 250 0 324 552 1 1
MPG HSD17B14 599 0 0 599 1 1
MPG SNRNP25 0 0 202 241 1 1
MPG PIGL 0 0 54 189 1 1
MPG LIPT2 0 0 0 173 1 1
MPG ENSG00000257767 0 0 0 196 1 1
MPG ALKBH1 0 0 560 568 1 1
MPG APLF 0 0 129 220 1 1
MPG RPL10 128 0 142 313 1 1
MPG THRB 213 0 0 213 1 1
MPG ADPRHL2 0 0 43 170 1 1
MPG MCM6 0 0 73 251 1 1
MPG PPAT 0 0 126 259 1 1
MPG RXRA 213 0 0 240 1 1
MPG CELSR2 0 0 81 154 1 1
MPG RACGAP1 270 0 0 273 1 1
MPG LYPD2 0 0 0 252 1 1
MPG MORF4L1 270 0 0 348 1 1
MPG TFB2M 0 0 0 362 1 1
MPG ERCC5 0 0 96 179 1 1
MPG GPI 0 0 142 193 1 2
MPG ERCC1 0 0 338 338 1 1
MPG OLA1 0 0 0 157 1 1
MPG RRP7A 270 0 0 301 1 1
MPG COMTD1 0 0 0 155 1 1
MPG KPRP 270 0 0 270 1 1
MPG TLK2 0 0 0 169 1 1
MPG SMUG1 0 0 601 601 1 1
MPG TEKT4 0 0 156 205 1 1
MPG PARG 0 0 232 231 1 1
MPG BRCA2 0 0 210 210 1 1
MPG MBD4 0 0 505 527 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0019104 Molecular Function DNA N-glycosylase activity enables TAS
GO:0008725 Molecular Function DNA-3-methyladenine glycosylase activity enables IEA
GO:0052822 Molecular Function DNA-3-methylguanine glycosylase activity enables IEA
GO:0052821 Molecular Function DNA-7-methyladenine glycosylase activity enables IEA
GO:0043916 Molecular Function DNA-7-methylguanine glycosylase activity enables IEA
GO:0003905 Molecular Function alkylbase DNA N-glycosylase activity enables IBA
GO:0003684 Molecular Function damaged DNA binding enables TAS
GO:0005515 Molecular Function protein binding enables IPI
GO:0006307 Biological Process DNA dealkylation involved in DNA repair involved_in TAS
GO:0006284 Biological Process base-excision repair involved_in IBA
GO:0045007 Biological Process depurination involved_in TAS
GO:0005829 Cellular Component cytosol located_in IDA
GO:0042645 Cellular Component mitochondrial nucleoid located_in IEA
GO:0005654 Cellular Component nucleoplasm located_in IDA
GO:0005654 Cellular Component nucleoplasm located_in TAS
Pathways
Name DB ID
Recognition and association of DNA glycosylase with site containing an affected purine Reactome R-HSA-110330
Cleavage of the damaged purine Reactome R-HSA-110331
Displacement of DNA glycosylase by APEX1 Reactome R-HSA-110357
Base Excision Repair Reactome R-HSA-73884
DNA Repair Reactome R-HSA-73894
Depurination Reactome R-HSA-73927
Base-Excision Repair, AP Site Formation Reactome R-HSA-73929
Resolution of Abasic Sites (AP sites) Reactome R-HSA-73933
DNA repair pathways, full network (WP4946) WikiPathways WP4946_r117703
Base excision repair (WP4752) WikiPathways WP4752_r119239
Transcripts
Accession Version MolecularType Name NCBI Comments
NM_001015054 3 mRNA transcript variant 3 NC_000016 Reference
NM_002434 4 mRNA transcript variant 1 NC_000016 Reference
NM_001015052 3 mRNA transcript variant 2 NC_000016 Reference