NPC1

NPC intracellular cholesterol transporter 1
General Information
Name NPC intracellular cholesterol transporter 1
Alias
  • NPC intracellular cholesterol transporter 1
  • Niemann-Pick C1 protein
  • truncated Niemann-Pick C1
Synonyms SLC65A1 NPC POGZ
Gene_family Solute carriers
organism Homo sapiens
entrez_id 4864
location 18q11.2
transcript_count 10
exon_count 28
Cross References
Location
by NCBI GRCh38.p14
    Summary
      Entrez This gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain. It is predicted to have a cytoplasmic C-terminus, 13 transmembrane domains, and 3 large loops in the lumen of the endosome - the last loop being at the N-terminus. This protein transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolized and released as free cholesterol. Defects in this gene cause Niemann-Pick type C disease, a rare autosomal recessive neurodegenerative disorder characterized by over accumulation of cholesterol and glycosphingolipids in late endosomal/lysosomal compartments.[provided by RefSeq, Aug 2009]
      Stringdb Niemann-Pick C1 protein; Intracellular cholesterol transporter which acts in concert with NPC2 and plays an important role in the egress of cholesterol from the endosomal/lysosomal compartment. Both NPC1 and NPC2 function as the cellular 'tag team duo' (TTD) to catalyze the mobilization of cholesterol within the multivesicular environment of the late endosome (LE) to effect egress through the limiting bilayer of the LE. NPC2 binds unesterified cholesterol that has been released from LDLs in the lumen of the late endosomes/lysosomes and transfers it to the cholesterol-binding pocket of [...]
      nextProt (Microbial infection) Acts as an endosomal entry receptor for ebolavirus.
    Interactions
    NCBI
    A A.Source B B.DB B.Source Description PubMed
    NPC1 BioGRID ORF3a GeneID BioGRID Proximity Label-MS
    NPC1 BioGRID E GeneID BioGRID Proximity Label-MS
    NPC1 BioGRID PEBP1 GeneID BioGRID Cross-Linking-MS (XL-MS)
    NPC1 BioGRID N GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
    NPC1 BioGRID DYRK1A GeneID BioGRID Two-hybrid
    NPC1 BioGRID TGOLN2 GeneID BioGRID Proximity Label-MS
    NPC1 BioGRID TOP3B GeneID BioGRID Affinity Capture-RNA
    NPC1 BioGRID TRIM67 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID HSPA8 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID LMNA GeneID BioGRID Proximity Label-MS
    NPC1 BioGRID RAB7A GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Proximity Label-MS
    NPC1 BioGRID TAF12 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID CANX GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID LAMP1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID CDC42 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID RHOA GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID TMEM192 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID TMEM106B GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
    NPC1 BioGRID TMPRSS4 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID SIGMAR1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID EDEM1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID LPAR2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID OR10H1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID FBXO6 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID FBXO2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID B3GALT4 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID S1PR4 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID VIPR1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID VEGFB GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID PTPRK GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID PON2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID LGALS8 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID LGALS1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID HLA-DRB1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID GP9 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID FPR2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID CNGA4 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID CLGN GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID C5AR1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID P2RY8 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID SIGLECL1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID TMPRSS12 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID C15orf32 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID NCEH1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID SPPL2B GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ATG10 GeneID BioGRID Phenotypic Enhancement
    NPC1 BioGRID ATG3 GeneID BioGRID Phenotypic Enhancement
    NPC1 BioGRID LAMTOR1 GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
    NPC1 BioGRID RIGI GeneID BioGRID Affinity Capture-RNA
    NPC1 BioGRID RAB9A GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
    NPC1 BioGRID RPN1 GeneID BioGRID Proximity Label-MS
    NPC1 BioGRID DHFR2 GeneID BioGRID Proximity Label-MS
    NPC1 BioGRID GJD3 GeneID BioGRID Proximity Label-MS
    NPC1 BioGRID LAMP2 GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
    NPC1 BioGRID LGALS9 GeneID BioGRID Proximity Label-MS
    NPC1 BioGRID DNAJC16 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID NEDD4L GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ATP11A GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID FAF2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID CLCC1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ERP44 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID EMC1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID RAB18 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID SYNPO GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID GABARAPL2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID RNF13 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ERLIN2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID RER1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID SLC27A2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID GCN1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID RAB32 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID CKAP4 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID LMAN2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID STARD3 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID PGRMC1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID VTI1B GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID SEC23A GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID PGRMC2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID MYL9 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID TCIRG1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID FLOT1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ARPC2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ACTR2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ACTR3 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ARPC1B GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ARPC4 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID SCAMP3 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ABCB6 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID NR1I3 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID RBM8A GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID FAM20B GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID SPCS2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID MLEC GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID EMC2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID SEC22B GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ATP6V1G1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID MPDU1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID SCAMP1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID STX8 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ABCG2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ECEL1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID SNRNP40 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID LRRFIP2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID BUB3 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID SYNGR2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID SLC16A3 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ATP6V0D1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID PIGQ GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID GPRC5A GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID AP1M1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID VAMP8 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID LAMTOR3 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID CUL1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID STX7 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID SLC7A5 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID UBB GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID PHLDA2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID TSG101 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID TPM4 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID TPM1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID TMPO GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID TLR3 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID TGFBR1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID VAMP7 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID STAT3 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID SSR1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID SNRPE GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID SNRPA1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID SMARCA4 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID SLC16A1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID SLC3A2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID SLC2A1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID SLC1A5 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID SEL1L GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID SDCBP GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID RRAS GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID RPN2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID RNH1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID TRIM27 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID RBBP4 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID RAP2B GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID RALA GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID RAB5C GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID RAB6A GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID RAB4A GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID RAB2A GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID RAB1A GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID PSMC3 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID PSMA5 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID PPP1CB GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID POR GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID PLD1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID PNP GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID NEDD4 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID NDUFA9 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID NCBP1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID MYO1C GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID MYH10 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID MYO1B GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID MCAM GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID LNPEP GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ABLIM1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID L1CAM GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID STT3A GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ITGB1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID IGF2R GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID HMOX1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID HLA-C GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID HLA-A GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID HDAC2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID GNAS GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID GNAI3 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID GNAI2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID B4GALT1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID NIPSNAP2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID GALNT2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID FYN GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID FLOT2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID EPHX1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID STOM GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID EMD GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID DSG2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID CYB5R3 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID DHCR24 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID DDOST GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID CD55 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID CYP51A1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID CSNK2A1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID CS GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID CPT1A GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID COX6C GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID CLTB GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID CLTA GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID CLPTM1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID CLN3 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID CLCN7 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID AP2M1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID TMEM214 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID DNAJB12 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID LY6K GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID TMED9 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID TMCO1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID SLC38A2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID TPCN1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID GALNT7 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID TM7SF3 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID SELENOT GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID GDE1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID RAB14 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID HACD3 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID LIMA1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID THEM6 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID SPG21 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ABHD17B GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID TMX2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID DERL2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID TMED5 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ATP6V0A4 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID UBQLN1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID TMOD3 GeneID BioGRID Affinity Capture-MS; Co-fractionation
    NPC1 BioGRID LAMTOR2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ERLEC1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID SLC39A1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID AGO2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ATP2C1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID TBL2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID MYOF GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID B3GAT3 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID PNKD GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID BACE2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID SDF2L1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID STX12 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID CORO1C GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID WBP2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ATP6V0A2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID TRAM1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID NCSTN GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ESYT1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID MAP1LC3B2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID GPX8 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID UBAC2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ATP11C GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ZDHHC20 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID DAGLB GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID TPCN2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID STT3B GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID RAB12 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID RPL22L1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ITPRIPL2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID SLC30A7 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID BRI3BP GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID HGSNAT GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ARL8A GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID MFSD12 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID STK11IP GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID PIP4P1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID CCDC32 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID SLC49A4 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID GHDC GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID SYVN1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID MAGT1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID SPNS1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID RAB34 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID RAB1B GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ARPC5L GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID LMAN2L GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID TMX1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID CLPTM1L GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID DNAJC5 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID PLEKHH3 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID DNAJB14 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID WLS GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID SPRING1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID STEAP4 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID MBOAT7 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID APOO GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID TMBIM1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID SPCS3 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID GNB4 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID SRPRB GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID CPNE5 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID GRAMD1A GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID NUFIP2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ESYT2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID CD70 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID CD44 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID SCARB2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID SCARB1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID CAPZA1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID BSG GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID AUP1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ATP7B GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ATP6AP1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ATP6V0A1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ATP6V1E1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ATP6V0C GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ATP6V1B2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ATP6V1A GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ATP2A2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ATP1B3 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ATP1B1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ATP1A1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ASPH GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ARF4 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID AMFR GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ALPP GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ALDH3A2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID AP1G1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID AP1B1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID AP2A2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ACTN1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ACP2 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID RAB22A GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ERGIC1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID RTN4 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID APMAP GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID AGTRAP GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID CCDC47 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID SLC12A9 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID UGGT1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID EMC7 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID GPRC5C GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID TMEM30A GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID TMEM184C GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID RAB20 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID PI4K2A GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ATAD3A GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID ARL8B GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID SLC35F6 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID PARP16 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID CDKAL1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID RETSAT GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID PIGG GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID HSCB GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID BUD31 GeneID BioGRID Two-hybrid
    NPC1 BioGRID MC4R GeneID BioGRID Two-hybrid
    NPC1 BioGRID GPR35 GeneID BioGRID Two-hybrid
    NPC1 BioGRID PLEKHA4 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID WWP1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID LMBR1L GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID CSK GeneID BioGRID Synthetic Lethality
    NPC1 BioGRID MTDH GeneID BioGRID Protein-RNA
    NPC1 BioGRID VIRMA GeneID BioGRID Affinity Capture-RNA
    NPC1 BioGRID TPRA1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID IL17RC GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID LGR4 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID MRPS28 GeneID BioGRID Co-fractionation
    NPC1 BioGRID STING1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID UNC93B1 GeneID BioGRID Affinity Capture-MS
    NPC1 BioGRID LRP6 GeneID BioGRID Affinity Capture-Western
    NPC1 BioGRID OSBPL5 GeneID BioGRID Affinity Capture-Western
    NPC1 BioGRID VPS4A GeneID BioGRID Affinity Capture-Western; Co-localization; Reconstituted Complex
    StringDB
    A B experiments database textmining combined score hadb nhadb
    NPC1 CYP11A1 0 0 211 229 1 1
    NPC1 ABCB1 0 0 60 198 1 1
    NPC1 FRRS1L 0 0 112 212 1 1
    NPC1 MAPT 0 0 261 307 1 2
    NPC1 BECN1 0 0 294 454 1 2
    NPC1 ABCC1 0 0 46 478 1 1
    NPC1 TMEM110 0 0 0 246 1 1
    NPC1 CMYA5 0 0 0 188 1 1
    NPC1 OLR1 0 0 161 161 1 1
    NPC1 ERLIN2 0 0 161 244 1 1
    NPC1 ACADVL 0 0 90 256 1 1
    NPC1 SEC62 0 0 134 193 1 1
    NPC1 GPR111 0 0 0 150 1 1
    NPC1 ITPKA 0 0 57 186 1 1
    NPC1 SCD5 0 0 92 182 1 1
    NPC1 SCN8A 0 0 70 264 1 1
    NPC1 CD81 0 0 95 215 1 1
    NPC1 LPCAT2 0 0 0 162 1 1
    NPC1 ZDHHC18 0 0 156 193 1 1
    NPC1 SIGMAR1 0 0 150 173 1 1
    NPC1 WDR59 0 0 67 152 1 1
    NPC1 FAF1 0 0 0 240 1 1
    NPC1 RABAC1 0 0 0 150 1 1
    NPC1 PDHX 0 0 0 159 1 1
    NPC1 EMR3 0 0 0 154 1 1
    NPC1 PKN2 0 0 56 156 1 1
    NPC1 MECR 0 0 88 170 1 1
    NPC1 C18orf8 0 0 212 260 1 1
    NPC1 TKT 0 0 0 171 1 1
    NPC1 GUSB 0 0 125 246 1 1
    NPC1 MTCH2 0 0 506 506 1 1
    NPC1 GSK3B 0 0 112 157 1 2
    NPC1 ST3GAL5 0 0 138 171 1 1
    NPC1 AGPAT2 0 0 81 210 1 1
    NPC1 SLC30A4 0 0 96 187 1 1
    NPC1 FLOT2 0 0 134 193 1 1
    NPC1 ATG16L1 0 0 181 198 1 2
    NPC1 SMPD1 0 0 682 747 1 1
    NPC1 CEBPB 0 0 74 169 1 1
    NPC1 GPR126 0 0 0 150 1 1
    NPC1 USE1 0 0 0 200 1 1
    NPC1 TKTL2 0 0 0 160 1 1
    NPC1 ABCB4 0 0 135 258 1 1
    NPC1 REL 0 0 0 284 1 1
    NPC1 AGPAT9 0 0 0 295 1 1
    NPC1 HADH 0 0 294 428 1 1
    NPC1 SLC6A14 0 0 606 606 1 1
    NPC1 CASP3 0 0 166 183 1 2
    NPC1 CTSS 0 0 218 245 1 1
    NPC1 STX16 0 0 113 267 1 1
    NPC1 ABCA7 0 0 134 193 1 1
    NPC1 IHH 0 0 135 229 1 1
    NPC1 SLC1A1 0 0 82 173 1 1
    NPC1 ASAH1 0 0 392 392 1 1
    NPC1 SACS 0 0 72 221 1 1
    NPC1 GPR97 0 0 0 150 1 1
    NPC1 B3GNT5 0 0 91 162 1 1
    NPC1 CHFR 0 0 0 158 1 1
    NPC1 SLC27A2 0 0 166 184 1 1
    NPC1 YARS2 0 0 81 177 1 1
    NPC1 CLN6 0 0 293 294 1 1
    NPC1 SKAP1 0 0 96 346 1 1
    NPC1 GAPDHS 0 0 0 188 1 1
    NPC1 PPIL4 0 0 0 376 1 1
    NPC1 TRAFD1 0 0 107 170 1 1
    NPC1 BST2 0 0 199 199 1 1
    NPC1 HHEX 0 0 66 164 1 1
    NPC1 NR1H4 0 0 308 307 1 1
    NPC1 TSPAN1 0 0 0 181 1 1
    NPC1 FATE1 0 0 455 455 1 1
    NPC1 M6PR 0 0 391 390 1 1
    NPC1 ATP7B 0 0 258 275 1 1
    NPC1 GNPDA2 0 0 545 558 1 1
    NPC1 C6orf211 0 0 95 174 1 1
    NPC1 TSPAN6 0 0 0 159 1 1
    NPC1 COL4A3BP 0 0 325 377 1 1
    NPC1 SURF4 0 0 90 164 1 1
    NPC1 PRKCA 0 0 261 261 1 1
    NPC1 ULK1 0 0 113 173 1 2
    NPC1 VPS33B 0 0 150 203 1 1
    NPC1 SPHK2 0 0 193 243 1 1
    NPC1 MAP1LC3B 0 0 203 234 1 2
    NPC1 LSS 0 0 134 206 1 1
    NPC1 HHAT 0 0 143 307 1 1
    NPC1 SLC24A5 0 0 0 218 1 1
    NPC1 SPHK1 0 0 193 243 1 2
    NPC1 TSPAN8 0 0 0 301 1 1
    NPC1 EBP 0 0 187 203 1 1
    NPC1 GRAMD1B 0 0 231 295 1 1
    NPC1 TSG101 0 0 171 255 1 2
    NPC1 AGPAT4 0 0 95 265 1 1
    NPC1 TYRP1 0 0 299 581 1 1
    NPC1 HADHB 0 0 468 557 1 1
    NPC1 CYB5D2 0 0 0 535 1 1
    NPC1 AP4E1 0 0 74 166 1 1
    NPC1 SPINK2 0 0 108 163 1 1
    NPC1 ATP4A 0 0 166 214 1 1
    NPC1 APOA5 0 0 161 161 1 1
    NPC1 HSF4 0 0 136 338 1 1
    NPC1 PPT1 0 0 181 285 1 1
    NPC1 BRD8 0 0 54 167 1 1
    NPC1 LGR5 0 0 60 239 1 1
    NPC1 OPTN 0 0 155 154 1 2
    NPC1 PDK4 0 0 47 168 1 1
    NPC1 ESR1 0 0 165 165 1 1
    NPC1 ABCD1 0 0 69 163 1 1
    NPC1 MMACHC 0 0 155 172 1 1
    NPC1 ENSG00000100926 0 0 66 286 1 1
    NPC1 OSBP 0 0 614 667 1 1
    NPC1 TSPAN18 0 0 0 159 1 1
    NPC1 MDH1 0 0 0 255 1 1
    NPC1 ABCA2 0 0 166 238 1 1
    NPC1 RBFOX3 0 0 113 168 1 1
    NPC1 ATXN2L 0 0 173 173 1 1
    NPC1 PDCD6IP 0 0 48 340 1 1
    NPC1 CLEC10A 0 0 0 250 1 1
    NPC1 ATP13A2 0 0 226 272 1 2
    NPC1 CHIA 0 0 54 152 1 1
    NPC1 VDR 0 0 74 304 1 1
    NPC1 RPL18 0 0 95 157 1 1
    NPC1 VAPB 0 0 234 234 1 1
    NPC1 SCP2 0 0 322 343 1 1
    NPC1 NFYC 0 0 218 353 1 1
    NPC1 DNAJC6 0 0 95 254 1 1
    NPC1 LCT 0 0 0 217 1 1
    NPC1 MRPS28 271 0 0 271 1 1
    NPC1 TNF 0 0 217 231 1 1
    NPC1 FABP1 0 0 171 208 1 1
    NPC1 MERTK 0 0 67 316 1 1
    NPC1 UVRAG 0 0 146 231 1 2
    NPC1 ITIH4 0 0 147 155 1 1
    NPC1 GPR115 0 0 0 150 1 1
    NPC1 LIPG 0 0 167 167 1 1
    NPC1 CCPG1 0 0 134 227 1 1
    NPC1 LAMTOR2 0 0 86 188 1 1
    NPC1 DRAM1 0 0 161 172 1 2
    NPC1 RAB7A 0 0 518 577 1 2
    NPC1 NPR3 0 0 92 186 1 1
    NPC1 CD9 0 0 66 178 1 1
    NPC1 ATP12A 0 0 171 217 1 1
    NPC1 NAGA 0 0 205 254 1 1
    NPC1 ATG4B 0 0 109 174 1 2
    NPC1 QPCTL 0 0 260 260 1 1
    NPC1 TFRC 0 0 261 528 1 1
    NPC1 RNFT2 0 0 0 158 1 1
    NPC1 STAR 0 0 451 461 1 1
    NPC1 HEXB 0 0 182 268 1 1
    NPC1 SREBF2 0 0 622 800 1 1
    NPC1 CTNNAL1 0 0 56 170 1 1
    NPC1 INS-IGF2 0 0 0 210 1 1
    NPC1 MTIF3 0 0 194 221 1 1
    NPC1 STIM1 0 0 113 166 1 2
    NPC1 ABCG2 0 0 92 200 1 1
    NPC1 ABCB5 0 0 94 222 1 1
    NPC1 TMEM97 0 0 937 937 1 1
    NPC1 LPGAT1 0 0 147 499 1 1
    NPC1 TSPAN10 0 0 0 201 1 1
    NPC1 RPS6KB1 0 0 149 242 1 2
    NPC1 PDPK1 0 0 0 250 1 2
    NPC1 TAL1 0 0 0 192 1 1
    NPC1 THEG 0 0 161 226 1 1
    NPC1 MDM1 0 0 135 221 1 1
    NPC1 PCSK2 0 0 49 290 1 1
    NPC1 SLC17A5 0 0 210 364 1 1
    NPC1 TMEM160 0 0 245 250 1 1
    NPC1 VPS41 0 0 95 162 1 1
    NPC1 CANX 0 0 282 282 1 2
    NPC1 FAF2 0 0 67 260 1 1
    NPC1 SLC39A8 0 0 135 158 1 1
    NPC1 KCTD15 0 0 509 509 1 1
    NPC1 GPAM 0 0 212 233 1 1
    NPC1 GPR113 0 0 0 150 1 1
    NPC1 ARHGAP6 0 0 66 185 1 1
    NPC1 ACOT8 0 0 171 206 1 1
    NPC1 CD97 0 0 0 154 1 1
    NPC1 TSPAN4 0 0 0 177 1 1
    NPC1 CLN5 0 0 209 324 1 1
    NPC1 HSD17B4 0 0 164 163 1 1
    NPC1 TRIP11 0 0 93 195 1 1
    NPC1 TGOLN2 0 0 180 191 1 1
    NPC1 APLP2 0 0 107 182 1 1
    NPC1 DHCR24 0 0 261 277 1 1
    NPC1 ABCC12 0 0 0 278 1 1
    NPC1 HSD3B7 0 0 122 181 1 1
    NPC1 MC4R 86 0 504 527 1 1
    NPC1 ABCD3 0 0 157 215 1 1
    NPC1 TPRA1 234 0 0 234 1 1
    NPC1 CLCN7 0 0 120 230 1 1
    NPC1 UPK1A 0 0 0 156 1 1
    NPC1 CHST8 0 0 162 161 1 1
    NPC1 STX17 0 0 151 165 1 2
    NPC1 HAS2 0 0 0 206 1 1
    NPC1 CD82 0 0 0 193 1 1
    NPC1 HSD17B12 0 0 143 155 1 1
    NPC1 GLTP 0 0 206 230 1 1
    NPC1 TSPAN17 0 0 0 150 1 1
    NPC1 ACLY 0 0 106 185 1 1
    NPC1 APOD 0 0 294 314 1 1
    NPC1 DMXL2 0 0 75 150 1 1
    NPC1 COASY 0 0 108 157 1 1
    NPC1 DNMBP 0 0 81 163 1 1
    NPC1 RHBDD3 0 0 0 176 1 1
    NPC1 RABGEF1 0 0 71 170 1 1
    NPC1 PQLC2 0 0 72 294 1 1
    NPC1 SCD 0 0 170 252 1 1
    NPC1 SORL1 0 0 285 342 1 1
    NPC1 GPR112 0 0 0 150 1 1
    NPC1 SRC 0 0 139 153 1 1
    NPC1 SLC29A3 0 0 0 313 1 1
    NPC1 PCSK9 0 0 190 338 1 1
    NPC1 CD47 0 0 0 416 1 1
    NPC1 EEA1 0 0 326 378 1 1
    NPC1 DGAT2 0 0 122 210 1 1
    NPC1 GPR64 0 0 0 150 1 1
    NPC1 TAP1 0 0 0 166 1 1
    NPC1 CADM2 0 0 170 169 1 1
    NPC1 TSPAN5 0 0 0 150 1 1
    NPC1 PTPLAD1 0 0 0 159 1 1
    NPC1 VLDLR 0 0 322 340 1 1
    NPC1 IGF2R 0 0 194 194 1 1
    NPC1 NR1I2 0 0 539 539 1 1
    NPC1 SLC24A3 0 0 0 191 1 1
    NPC1 GPRC5B 0 0 170 169 1 1
    NPC1 PIKFYVE 0 0 324 715 1 1
    NPC1 LGR6 0 0 0 224 1 1
    NPC1 LPHN3 0 0 0 150 1 1
    NPC1 KDSR 0 0 141 296 1 1
    NPC1 FABP2 0 0 231 289 1 1
    NPC1 ACE2 0 0 209 263 1 1
    NPC1 ABCG8 0 0 321 402 1 1
    NPC1 ATF1 0 0 49 166 1 1
    NPC1 CD4 0 0 144 263 1 1
    NPC1 ACOX2 0 0 112 173 1 1
    NPC1 LYPLAL1 0 0 193 194 1 1
    NPC1 TPST2 0 0 72 279 1 1
    NPC1 PPARG 0 0 270 270 1 1
    NPC1 MARCH6 0 0 137 320 1 1
    NPC1 AKT1 0 0 240 276 1 2
    NPC1 NPC2 932 900 990 999 1 1
    NPC1 SNAP29 0 0 134 152 1 2
    NPC1 SNCA 0 0 324 338 1 2
    NPC1 GM2A 0 0 255 270 1 1
    NPC1 RHBDD2 0 0 0 176 1 1
    NPC1 CAV1 270 0 368 519 1 1
    NPC1 SLC35F6 0 0 135 341 1 1
    NPC1 ZFYVE27 0 0 212 216 1 1
    NPC1 MYLIP 0 0 123 185 1 1
    NPC1 TNKS 0 0 134 153 1 1
    NPC1 CALB1 0 0 231 287 1 1
    NPC1 SIGLEC1 0 0 0 191 1 1
    NPC1 EARS2 0 0 74 199 1 1
    NPC1 SERPINA1 0 0 112 173 1 2
    NPC1 PSAPL1 0 0 0 163 1 1
    NPC1 ITPR3 0 0 116 161 1 1
    NPC1 NXPH4 0 0 85 406 1 1
    NPC1 DCAF10 0 0 151 221 1 1
    NPC1 RPL7 0 0 0 175 1 1
    NPC1 TMEM173 157 0 112 219 1 1
    NPC1 TM9SF3 0 0 0 416 1 1
    NPC1 GRN 0 0 126 220 1 1
    NPC1 GOLGA2 0 0 171 171 1 1
    NPC1 VCP 0 0 90 150 1 2
    NPC1 LAMP2 0 0 459 514 1 2
    NPC1 HDLBP 0 0 123 195 1 1
    NPC1 SHH 0 0 249 331 1 1
    NPC1 MCOLN3 0 0 235 277 1 1
    NPC1 MCOLN2 0 0 216 259 1 1
    NPC1 CALR 0 0 155 229 1 1
    NPC1 TM9SF4 0 0 0 224 1 1
    NPC1 TCIRG1 0 0 120 228 1 1
    NPC1 HSPA8 0 0 154 168 1 2
    NPC1 RAB24 0 0 184 206 1 2
    NPC1 MTTP 0 0 187 260 1 1
    NPC1 HSD3B1 0 0 122 181 1 1
    NPC1 OSBPL6 0 0 456 493 1 1
    NPC1 ABCA13 0 0 90 225 1 1
    NPC1 GABARAPL1 0 0 125 205 1 2
    NPC1 UNC93B1 157 0 74 186 1 1
    NPC1 ABCG4 0 0 297 394 1 1
    NPC1 GPR137C 0 0 0 189 1 1
    NPC1 GPR114 0 0 0 150 1 1
    NPC1 BACE2 0 0 127 204 1 1
    NPC1 ATP8B1 0 0 459 547 1 1
    NPC1 TFEB 0 0 391 390 1 2
    NPC1 COX4I1 0 0 57 151 1 1
    NPC1 SGPL1 0 0 107 162 1 1
    NPC1 EXD1 0 0 150 236 1 1
    NPC1 DISP2 0 0 113 186 1 1
    NPC1 STARD4 0 0 502 511 1 1
    NPC1 RFK 0 0 66 310 1 1
    NPC1 SPG7 0 0 142 177 1 1
    NPC1 ACTB 0 0 264 274 1 1
    NPC1 TMOD3 271 0 0 271 1 1
    NPC1 INS 0 0 248 248 1 1
    NPC1 GAS6 0 0 91 165 1 1
    NPC1 YIPF2 0 0 0 244 1 1
    NPC1 SLC30A1 0 0 0 177 1 1
    NPC1 AUP1 0 0 57 223 1 1
    NPC1 LRRC47 0 0 112 170 1 1
    NPC1 UBE2QL1 0 0 124 199 1 1
    NPC1 AADACL3 0 0 202 374 1 1
    NPC1 SORCS3 0 0 75 172 1 1
    NPC1 SDHA 0 0 52 247 1 1
    NPC1 CTNS 0 0 232 328 1 1
    NPC1 FAP 0 0 0 160 1 1
    NPC1 FLOT1 0 0 209 263 1 1
    NPC1 DPP4 0 0 91 352 1 1
    NPC1 VPS54 0 0 116 164 1 1
    NPC1 DNM2 0 0 155 195 1 1
    NPC1 SLC24A1 0 0 0 191 1 1
    NPC1 CALML6 0 0 108 195 1 1
    NPC1 ATP8B2 0 0 0 188 1 1
    NPC1 DCTN1 0 0 235 252 1 1
    NPC1 ABCA1 0 0 820 838 1 1
    NPC1 SEC31B 0 0 97 294 1 1
    NPC1 CERS2 0 0 150 221 1 1
    NPC1 GPR133 0 0 0 150 1 1
    NPC1 CDK6 0 0 60 154 1 1
    NPC1 CP 0 0 229 228 1 1
    NPC1 HMGCS2 0 0 71 278 1 1
    NPC1 PTPRJ 0 0 0 182 1 1
    NPC1 TMEM18 0 0 510 513 1 1
    NPC1 PKP2 0 0 0 220 1 1
    NPC1 C12orf49 0 0 172 171 1 1
    NPC1 GNPTAB 0 0 123 317 1 1
    NPC1 ATP6V0A2 0 0 67 189 1 1
    NPC1 SDCCAG8 0 0 242 241 1 1
    NPC1 OSBPL7 0 0 108 348 1 1
    NPC1 VPS18 0 0 124 208 1 1
    NPC1 GRINA 0 0 0 165 1 1
    NPC1 TSPAN3 0 0 0 199 1 1
    NPC1 TSPAN16 0 0 231 330 1 1
    NPC1 MX2 0 0 53 159 1 1
    NPC1 PGRMC1 0 0 171 171 1 1
    NPC1 SEC23A 0 0 0 159 1 2
    NPC1 RPTOR 0 0 150 268 1 2
    NPC1 GRAMD1A 0 0 212 277 1 1
    NPC1 ITPR1 0 0 112 157 1 2
    NPC1 POMC 0 0 157 278 1 1
    NPC1 RBMS2 0 0 0 195 1 1
    NPC1 IL13RA2 0 0 0 394 1 1
    NPC1 OR6B1 0 0 174 180 1 1
    NPC1 FASN 0 0 234 314 1 1
    NPC1 MX1 0 0 0 207 1 1
    NPC1 BDP1 0 0 65 174 1 1
    NPC1 CYP7B1 0 0 228 245 1 1
    NPC1 MSRA 0 0 253 252 1 1
    NPC1 YIPF3 0 0 0 402 1 1
    NPC1 APOA1BP 0 0 93 233 1 1
    NPC1 HEG1 0 0 0 190 1 1
    NPC1 ACACA 0 0 142 306 1 1
    NPC1 TFAP2B 0 0 213 213 1 1
    NPC1 IRGM 0 0 161 162 1 2
    NPC1 TMEM192 0 0 228 231 1 1
    NPC1 MYC 0 0 152 170 1 2
    NPC1 IFITM3 0 0 160 159 1 1
    NPC1 CYP51A1 0 0 134 164 1 1
    NPC1 STIMATE-MUSTN1 0 0 0 246 1 1
    NPC1 PPIG 0 0 90 194 1 1
    NPC1 SLC1A6 0 0 102 191 1 1
    NPC1 SMPDL3B 0 0 0 178 1 1
    NPC1 CEL 0 0 182 202 1 1
    NPC1 MECP2 0 0 43 159 1 1
    NPC1 NEGR1 0 0 469 469 1 1
    NPC1 EML4 0 0 0 228 1 1
    NPC1 ACER3 0 0 0 187 1 1
    NPC1 SLC30A10 0 0 0 177 1 1
    NPC1 ASGR1 0 0 216 479 1 1
    NPC1 FURIN 0 0 370 530 1 1
    NPC1 SLC29A2 0 0 0 313 1 1
    NPC1 RSPH1 0 0 67 183 1 1
    NPC1 TADA2A 0 0 66 210 1 1
    NPC1 CH25H 0 0 175 231 1 1
    NPC1 MYCN 0 0 67 462 1 1
    NPC1 CIDEB 0 0 96 203 1 1
    NPC1 UGT3A1 0 0 156 178 1 1
    NPC1 MPEG1 0 0 59 193 1 1
    NPC1 ACSL1 0 0 90 208 1 1
    NPC1 NELFCD 0 0 0 302 1 1
    NPC1 SLC2A2 0 0 0 161 1 1
    NPC1 SNAP23 0 0 140 159 1 1
    NPC1 NRXN3 0 0 205 205 1 1
    NPC1 NPB 0 0 250 250 1 1
    NPC1 SNX14 0 0 126 231 1 1
    NPC1 GOLIM4 0 0 57 161 1 1
    NPC1 SUMF1 0 0 271 428 1 1
    NPC1 DHH 0 0 123 219 1 1
    NPC1 GAA 0 0 145 319 1 2
    NPC1 CFTR 0 0 240 395 1 1
    NPC1 ATP6V0C 0 0 112 209 1 2
    NPC1 RAB4A 0 0 187 210 1 1
    NPC1 CDK4 0 0 46 193 1 1
    NPC1 ABCA3 0 0 260 324 1 1
    NPC1 SUSD2 0 0 0 277 1 1
    NPC1 RHPN1 0 0 0 168 1 1
    NPC1 FITM2 0 0 0 189 1 1
    NPC1 AGO2 0 0 113 154 1 1
    NPC1 ATP6V0D1 0 0 0 189 1 1
    NPC1 RAB9A 0 0 217 250 1 2
    NPC1 KIF18B 0 0 67 150 1 1
    NPC1 HSCB 270 0 0 270 1 1
    NPC1 HGS 0 0 161 207 1 2
    NPC1 ATP8B4 0 0 0 188 1 1
    NPC1 ARV1 0 0 167 224 1 1
    NPC1 MAP1LC3A 0 0 140 243 1 2
    NPC1 LIPE 0 0 143 187 1 1
    NPC1 MIER3 0 0 95 191 1 1
    NPC1 EPHA2 0 0 68 258 1 1
    NPC1 TM4SF20 0 0 113 153 1 1
    NPC1 DHCR7 0 0 370 387 1 1
    NPC1 ACSL3 0 0 135 156 1 1
    NPC1 ACSL5 0 0 124 186 1 1
    NPC1 RNFT1 0 0 0 158 1 1
    NPC1 BAAT 0 0 150 170 1 1
    NPC1 SEC16B 0 0 468 468 1 2
    NPC1 GPR144 0 0 0 150 1 1
    NPC1 RPS7 0 0 46 443 1 1
    NPC1 IL1B 0 0 193 193 1 1
    NPC1 BTD 0 0 73 299 1 1
    NPC1 CLN3 0 0 402 476 1 2
    NPC1 PQLC1 0 0 0 193 1 1
    NPC1 KIAA1429 270 0 0 270 1 1
    NPC1 NCR1 0 0 229 228 1 1
    NPC1 CHMP2B 0 0 142 224 1 2
    NPC1 UCP2 0 0 304 304 1 1
    NPC1 IL6 0 0 171 171 1 1
    NPC1 NUDT3 0 0 209 209 1 1
    NPC1 P4HTM 0 0 57 253 1 1
    NPC1 LGR4 270 0 96 591 1 1
    NPC1 CROT 0 0 561 628 1 1
    NPC1 VPS4A 270 0 166 365 1 1
    NPC1 FABP6 0 0 143 155 1 1
    NPC1 PSEN2 0 0 157 214 1 1
    NPC1 ABCB11 0 0 402 559 1 1
    NPC1 VNN1 0 0 58 161 1 1
    NPC1 SEC61A1 0 0 167 173 1 1
    NPC1 SYT7 0 0 321 363 1 1
    NPC1 SMO 0 0 113 343 1 1
    NPC1 SORT1 0 0 163 224 1 1
    NPC1 NUS1 0 0 207 216 1 1
    NPC1 SNED1 0 0 0 261 1 1
    NPC1 PCSK6 0 0 0 284 1 1
    NPC1 OSBPL1A 0 0 242 410 1 1
    NPC1 SCAP 0 0 595 330 1 1
    NPC1 ETFA 0 0 721 721 1 1
    NPC1 HAVCR1 0 0 159 194 1 1
    NPC1 RALYL 0 0 185 204 1 1
    NPC1 TECTA 0 0 0 261 1 1
    NPC1 APOA4 0 0 125 165 1 1
    NPC1 EMR1 0 0 0 171 1 1
    NPC1 TLR4 0 0 218 278 1 1
    NPC1 TSPAN12 0 0 0 156 1 1
    NPC1 ATG14 0 0 135 225 1 2
    NPC1 GABARAPL2 0 0 139 231 1 2
    NPC1 AGPAT5 0 0 48 218 1 1
    NPC1 APOA1 0 0 500 514 1 1
    NPC1 CD14 0 0 0 208 1 1
    NPC1 SCUBE1 0 0 0 188 1 1
    NPC1 UMOD 0 0 0 638 1 1
    NPC1 PIK3R4 0 0 112 173 1 2
    NPC1 MAPRE2 0 0 122 184 1 1
    NPC1 ENSG00000250349 0 0 141 235 1 1
    NPC1 LINGO2 0 0 134 153 1 1
    NPC1 TMBIM1 0 0 54 176 1 1
    NPC1 LRP2 0 0 167 173 1 1
    NPC1 VAC14 0 0 215 232 1 1
    NPC1 TM9SF2 0 0 0 224 1 1
    NPC1 LRRK2 0 0 243 322 1 2
    NPC1 ATP6V0A4 0 0 94 212 1 1
    NPC1 STARD5 0 0 246 301 1 1
    NPC1 GRID2 0 0 117 173 1 2
    NPC1 MAN2B1 0 0 209 263 1 1
    NPC1 MATK 0 0 321 326 1 1
    NPC1 OSBPL11 0 0 134 184 1 1
    NPC1 AGPAT6 0 0 48 450 1 1
    NPC1 RRAGC 0 0 428 443 1 1
    NPC1 TFE3 0 0 141 164 1 1
    NPC1 HSPA5 0 0 140 193 1 2
    NPC1 UNC50 0 0 95 349 1 1
    NPC1 SLC35B2 0 0 96 354 1 1
    NPC1 SH2B1 0 0 556 556 1 1
    NPC1 TSPAN2 0 0 0 214 1 1
    NPC1 SOD2 0 0 77 254 1 1
    NPC1 FABP4 0 0 150 241 1 1
    NPC1 ADPGK 0 0 0 251 1 1
    NPC1 DLAT 0 0 70 270 1 1
    NPC1 ANGPTL3 0 0 212 226 1 1
    NPC1 JAZF1 0 0 81 279 1 1
    NPC1 NDRG3 0 0 0 205 1 1
    NPC1 MNS1 0 0 74 198 1 1
    NPC1 TSPO 0 0 181 200 1 1
    NPC1 NEU3 0 0 144 202 1 1
    NPC1 GOLGA1 0 0 134 154 1 1
    NPC1 ATG4D 0 0 103 180 1 2
    NPC1 LPCAT4 0 0 45 166 1 1
    NPC1 PLEKHM1 0 0 107 181 1 2
    NPC1 MYO5B 0 0 142 169 1 1
    NPC1 AP1G1 0 0 124 160 1 1
    NPC1 CLEC4M 0 0 359 429 1 1
    NPC1 CYP46A1 0 0 420 459 1 1
    NPC1 PFDN4 0 0 231 230 1 1
    NPC1 TSPAN9 0 0 0 177 1 1
    NPC1 NDE1 0 0 81 181 1 1
    NPC1 ATG12 0 0 179 180 1 2
    NPC1 NDUFA9 0 0 46 305 1 1
    NPC1 MGEA5 0 0 218 224 1 1
    NPC1 RASAL2 0 0 294 307 1 1
    NPC1 GPD2 0 0 113 373 1 1
    NPC1 SREBF1 0 0 486 725 1 2
    NPC1 FAM134B 0 0 202 234 1 1
    NPC1 UCP1 0 0 66 267 1 1
    NPC1 NFKBIA 0 0 54 234 1 1
    NPC1 GBA2 0 0 301 336 1 1
    NPC1 LEP 0 0 181 181 1 1
    NPC1 PANK2 0 0 235 239 1 1
    NPC1 WIPI1 0 0 103 183 1 2
    NPC1 FFAR4 0 0 438 438 1 1
    NPC1 STXBP5L 0 0 0 162 1 1
    NPC1 GABARAP 0 0 115 173 1 2
    NPC1 STX11 0 0 82 154 1 1
    NPC1 RHBDD1 0 0 0 176 1 1
    NPC1 PTEN 0 0 94 212 1 2
    NPC1 GFAP 0 0 206 234 1 2
    NPC1 TRMT13 0 0 0 208 1 1
    NPC1 ATP6V0A1 0 0 120 235 1 1
    NPC1 SNX17 0 0 137 190 1 1
    NPC1 LPHN1 0 0 0 150 1 1
    NPC1 ABCC10 0 0 0 236 1 1
    NPC1 MON2 0 0 0 217 1 1
    NPC1 FABP12 0 0 180 191 1 1
    NPC1 ATG7 0 0 231 297 1 2
    NPC1 FAIM2 0 0 560 570 1 1
    NPC1 LCLAT1 0 0 0 212 1 1
    NPC1 ICAM3 0 0 48 262 1 1
    NPC1 LCAT 0 0 245 327 1 1
    NPC1 TYRO3 0 0 244 618 1 1
    NPC1 CTSD 0 0 420 478 1 2
    NPC1 GPR116 0 0 0 150 1 1
    NPC1 FASTKD5 0 0 0 390 1 1
    NPC1 OSBPL9 0 0 218 235 1 1
    NPC1 OSBPL8 0 0 141 294 1 1
    NPC1 MDH1B 0 0 46 202 1 1
    NPC1 KPTN 0 0 143 214 1 1
    NPC1 GALC 0 0 245 320 1 1
    NPC1 UBE2J2 0 0 61 159 1 1
    NPC1 GLI1 0 0 134 157 1 1
    NPC1 MGLL 0 0 70 159 1 1
    NPC1 ANXA6 0 0 217 217 1 1
    NPC1 NCEH1 0 0 218 347 1 1
    NPC1 XBP1 0 0 95 233 1 2
    NPC1 ATG5 0 0 216 271 1 2
    NPC1 SLC17A2 0 0 55 157 1 1
    NPC1 YIPF1 0 0 0 244 1 1
    NPC1 MAP3K5 0 0 0 221 1 1
    NPC1 TMEM55B 0 0 170 201 1 1
    NPC1 BACE1 0 0 257 279 1 1
    NPC1 TSPAN33 0 0 0 158 1 1
    NPC1 CTSB 0 0 724 788 1 2
    NPC1 ACOX1 0 0 155 213 1 1
    NPC1 SPI1 0 0 63 206 1 1
    NPC1 ERVW-1 0 0 348 348 1 1
    NPC1 SMPD2 0 0 234 511 1 1
    NPC1 CD209 0 0 268 348 1 1
    NPC1 NRIP1 0 0 151 204 1 1
    NPC1 OSBP2 0 0 103 225 1 1
    NPC1 ATP11C 0 0 0 172 1 1
    NPC1 ABHD6 0 0 111 154 1 1
    NPC1 BDNF 0 0 297 297 1 2
    NPC1 MC3R 0 0 414 414 1 1
    NPC1 PAFAH1B1 0 0 73 157 1 1
    NPC1 PSD2 0 0 150 191 1 1
    NPC1 NEDD4L 0 0 0 173 1 1
    NPC1 APOB 0 0 364 394 1 1
    NPC1 PTER 0 0 603 603 1 1
    NPC1 PLEKHA4 270 0 0 270 1 1
    NPC1 ABCC6 0 0 0 432 1 1
    NPC1 CTNNBL1 0 0 263 263 1 1
    NPC1 ABCB10 0 0 0 162 1 1
    NPC1 TNNT2 0 0 0 219 1 1
    NPC1 PTCH1 0 0 344 199 1 1
    NPC1 LAMTOR3 0 0 91 216 1 1
    NPC1 CD63 0 0 258 564 1 1
    NPC1 LPHN2 0 0 0 150 1 1
    NPC1 TIMD4 0 0 157 158 1 1
    NPC1 PRKAA1 0 0 209 260 1 2
    NPC1 ANXA2 0 0 212 212 1 1
    NPC1 SPTLC2 0 0 112 157 1 1
    NPC1 PEX26 0 0 157 169 1 1
    NPC1 STARD3 0 0 681 713 1 1
    NPC1 HMGCR 0 0 508 602 1 1
    NPC1 LIPA 0 0 603 611 1 1
    NPC1 YWHAQ 0 0 137 176 1 1
    NPC1 TSPAN14 0 0 0 199 1 1
    NPC1 LRP6 270 0 63 292 1 1
    NPC1 AGPAT3 0 0 0 221 1 1
    NPC1 ABCG5 0 0 395 470 1 1
    NPC1 FDFT1 0 0 266 280 1 1
    NPC1 GBA 0 0 424 525 1 1
    NPC1 ATP2A2 0 0 95 164 1 1
    NPC1 LDLR 0 0 464 489 1 1
    NPC1 CHIT1 0 0 605 605 1 1
    NPC1 PTPLAD2 0 0 0 159 1 1
    NPC1 APOBR 0 0 193 193 1 1
    NPC1 PRKCD 0 0 52 152 1 2
    NPC1 MRPL16 0 0 95 187 1 1
    NPC1 VDAC1 0 0 156 157 1 2
    NPC1 RAB7B 0 0 625 635 1 1
    NPC1 VAMP7 0 0 134 150 1 1
    NPC1 BEAN1 0 0 124 221 1 1
    NPC1 ABCC9 0 0 0 327 1 1
    NPC1 RAB11A 0 0 245 244 1 1
    NPC1 CLEC5A 0 0 0 254 1 1
    NPC1 CLN8 0 0 193 198 1 1
    NPC1 CACNA1A 0 0 108 164 1 1
    NPC1 SORCS1 0 0 81 177 1 1
    NPC1 ELTD1 0 0 0 394 1 1
    NPC1 HNF4A 0 0 95 266 1 1
    NPC1 RNF139 0 0 242 335 1 1
    NPC1 NAGLU 0 0 97 153 1 1
    NPC1 HEXA 0 0 95 329 1 1
    NPC1 ATG3 0 0 134 214 1 2
    NPC1 LRP8 0 0 243 263 1 1
    NPC1 ENSG00000250264 0 0 0 162 1 1
    NPC1 SLC24A4 0 0 0 191 1 1
    NPC1 APOE 0 0 505 515 1 1
    NPC1 SLC29A4 0 0 0 258 1 1
    NPC1 FABP9 0 0 142 154 1 1
    NPC1 TGFBI 0 0 0 180 1 1
    NPC1 MGAM 0 0 211 250 1 1
    NPC1 SLC39A11 0 0 0 190 1 1
    NPC1 BSCL2 0 0 149 272 1 1
    NPC1 TOR4A 0 0 170 169 1 1
    NPC1 KLKB1 0 0 44 189 1 1
    NPC1 AXL 0 0 263 666 1 1
    NPC1 PTPN23 0 0 0 245 1 1
    NPC1 GP2 0 0 889 893 1 1
    NPC1 RDH16 0 0 74 176 1 1
    NPC1 PINK1 0 0 141 153 1 2
    NPC1 APOA2 0 0 136 168 1 1
    NPC1 HMGA1 0 0 180 179 1 1
    NPC1 RALY 0 0 107 222 1 1
    NPC1 GPT 0 0 205 205 1 1
    NPC1 DGKG 0 0 264 297 1 1
    NPC1 TMEM74 0 0 193 262 1 2
    NPC1 DROSHA 0 0 123 179 1 1
    NPC1 CLDN1 0 0 107 219 1 1
    NPC1 PSMD8 0 0 47 159 1 1
    NPC1 ACACB 0 0 62 250 1 1
    NPC1 MAP3K15 0 0 0 161 1 1
    NPC1 MBTPS1 0 0 142 192 1 1
    NPC1 DERL2 0 0 96 342 1 1
    NPC1 F13A1 0 0 84 252 1 1
    NPC1 ABCC11 0 0 0 236 1 1
    NPC1 TMEM68 0 0 0 162 1 1
    NPC1 KLHL10 0 0 0 235 1 1
    NPC1 CPT1A 0 0 395 468 1 1
    NPC1 CYP7A1 0 0 398 411 1 1
    NPC1 PCNX 0 0 103 195 1 1
    NPC1 AIF1 0 0 163 172 1 1
    NPC1 MANBA 0 0 203 339 1 1
    NPC1 STXBP5 0 0 0 162 1 1
    NPC1 ABCC5 0 0 0 278 1 1
    NPC1 AADACL4 0 0 0 248 1 1
    NPC1 XYLT1 0 0 53 177 1 1
    NPC1 AMFR 0 0 163 265 1 1
    NPC1 DISP1 0 0 253 268 1 1
    NPC1 SI 0 0 203 242 1 1
    NPC1 TPP1 0 0 310 429 1 1
    NPC1 SCN3A 0 0 57 161 1 1
    NPC1 FABP3 0 0 154 184 1 1
    NPC1 CTSF 0 0 150 296 1 1
    NPC1 FDPS 0 0 218 225 1 1
    NPC1 UBXN8 0 0 0 240 1 1
    NPC1 INSIG2 0 0 350 398 1 1
    NPC1 AGPAT1 0 0 95 214 1 1
    NPC1 SOD1 0 0 193 199 1 1
    NPC1 ELOVL6 0 0 107 164 1 1
    NPC1 TTPA 0 0 251 257 1 1
    NPC1 TSPAN19 0 0 0 201 1 1
    NPC1 IRS2 0 0 244 261 1 1
    NPC1 PLA2G15 0 0 194 215 1 1
    NPC1 ARSA 0 0 318 335 1 2
    NPC1 ESYT2 0 0 113 159 1 1
    NPC1 PLCH2 0 0 73 152 1 1
    NPC1 TREM2 0 0 129 162 1 1
    NPC1 MOCS2 0 0 107 174 1 1
    NPC1 ATG9A 0 0 127 302 1 2
    NPC1 SFTPB 0 0 70 188 1 1
    NPC1 SLC18B1 0 0 160 159 1 1
    NPC1 TULP3 0 0 108 199 1 1
    NPC1 FABP5 0 0 150 282 1 1
    NPC1 STX4 0 0 120 159 1 1
    NPC1 STX6 0 0 184 326 1 1
    NPC1 TMEM175 0 0 108 169 1 1
    NPC1 KPNA5 0 0 69 186 1 1
    NPC1 TMEM135 0 0 114 194 1 1
    NPC1 LDLRAP1 0 0 140 181 1 1
    NPC1 LCTL 0 0 0 217 1 1
    NPC1 SEC31A 0 0 0 182 1 1
    NPC1 ICAM1 0 0 134 201 1 1
    NPC1 S100A11 0 0 111 183 1 1
    NPC1 TSPAN13 0 0 0 185 1 1
    NPC1 TMEM245 0 0 113 206 1 1
    NPC1 ZCCHC16 0 0 66 209 1 1
    NPC1 PPP1R17 0 0 97 256 1 1
    NPC1 HSP90AA1 0 0 181 189 1 2
    NPC1 UGCG 0 0 561 594 1 1
    NPC1 FAM134C 0 0 247 390 1 1
    NPC1 RAB29 0 0 75 153 1 1
    NPC1 PSEN1 0 0 283 319 1 2
    NPC1 ESYT1 0 0 108 153 1 1
    NPC1 MSMO1 0 0 137 202 1 1
    NPC1 RNASEK 0 0 134 193 1 1
    NPC1 EMR2 0 0 0 154 1 1
    NPC1 SQSTM1 0 0 250 285 1 2
    NPC1 ABCG1 0 0 631 704 1 1
    NPC1 TKTL1 0 0 0 170 1 1
    NPC1 CDK5 0 0 142 183 1 2
    NPC1 LGALS8 271 0 96 313 1 1
    NPC1 SCARB1 0 0 470 498 1 1
    NPC1 GIPR 0 0 167 167 1 1
    NPC1 ARSG 0 0 91 158 1 1
    NPC1 SEC23B 0 0 0 159 1 2
    NPC1 ABCC4 0 0 0 278 1 1
    NPC1 SNCAIP 0 0 81 194 1 2
    NPC1 DAG1 0 0 134 296 1 1
    NPC1 DRAM2 0 0 166 178 1 2
    NPC1 CD68 0 0 184 185 1 1
    NPC1 OSBPL2 0 0 229 304 1 1
    NPC1 ALB 0 0 257 303 1 1
    NPC1 ABCC3 0 0 0 407 1 1
    NPC1 PMP2 0 0 101 162 1 1
    NPC1 PITPNM1 0 0 108 167 1 1
    NPC1 GTPBP1 0 0 989 989 1 1
    NPC1 SDR42E1 0 0 0 296 1 1
    NPC1 MAF 0 0 396 396 1 1
    NPC1 TAP2 0 0 0 162 1 1
    NPC1 ATG16L2 0 0 155 225 1 2
    NPC1 GLB1 0 0 135 222 1 1
    NPC1 ATP2A1 0 0 103 172 1 1
    NPC1 PAX6 0 0 88 150 1 1
    NPC1 ABCC8 0 0 74 350 1 1
    NPC1 NSDHL 0 0 167 223 1 1
    NPC1 CNTNAP1 0 0 0 170 1 1
    NPC1 SLC24A2 0 0 0 191 1 1
    NPC1 SGK494 0 0 0 157 1 1
    NPC1 AKR1D1 0 0 150 254 1 1
    NPC1 SIRT6 0 0 171 258 1 1
    NPC1 FAM134A 0 0 194 373 1 1
    NPC1 VPS35 0 0 143 163 1 1
    NPC1 ATP6V0D2 0 0 0 303 1 1
    NPC1 CDH12 0 0 108 169 1 1
    NPC1 BOC 0 0 140 210 1 1
    NPC1 RHPN2 0 0 0 168 1 1
    NPC1 MBTPS2 0 0 129 196 1 1
    NPC1 GPR56 0 0 0 150 1 1
    NPC1 HSPA4 0 0 184 193 1 1
    NPC1 ETV5 0 0 292 292 1 1
    NPC1 C17orf78 0 0 0 156 1 1
    NPC1 CLTC 0 0 120 198 1 1
    NPC1 DICER1 0 0 134 190 1 1
    NPC1 ATP6AP2 0 0 96 158 1 1
    NPC1 PTPRK 306 0 42 321 1 1
    NPC1 TRA2B 0 0 122 272 1 1
    NPC1 XPO5 0 0 58 162 1 1
    NPC1 DNPEP 0 0 73 199 1 1
    NPC1 CETP 0 0 284 284 1 1
    NPC1 PPARA 0 0 289 288 1 1
    NPC1 LPL 0 0 248 255 1 1
    NPC1 SLC1A2 0 0 87 178 1 1
    NPC1 SQLE 0 0 234 278 1 1
    NPC1 CYCS 0 0 122 160 1 1
    NPC1 SLC8B1 0 0 0 394 1 1
    NPC1 SORCS2 0 0 75 179 1 1
    NPC1 EGF 0 0 165 184 1 1
    NPC1 HGSNAT 0 0 49 176 1 1
    NPC1 CYP27A1 0 0 302 332 1 1
    NPC1 GPR110 0 0 0 150 1 1
    NPC1 GAK 0 0 92 325 1 1
    NPC1 PCSK1 0 0 358 392 1 1
    NPC1 P4HB 0 0 125 227 1 2
    NPC1 LMBRD1 0 0 112 205 1 1
    NPC1 ENSG00000261832 0 0 391 467 1 1
    NPC1 SOAT2 0 0 260 313 1 1
    NPC1 PTPLB 0 0 0 189 1 1
    NPC1 SCN2A 0 0 53 157 1 1
    NPC1 VAPA 0 0 336 351 1 1
    NPC1 HNF4G 0 0 0 188 1 1
    NPC1 ACP5 0 0 0 184 1 1
    NPC1 CACNB4 0 0 0 189 1 1
    NPC1 HHIP 0 0 142 195 1 1
    NPC1 TM9SF1 0 0 66 286 1 2
    NPC1 SLC1A3 0 0 96 160 1 1
    NPC1 IKBKAP 0 0 134 153 1 1
    NPC1 ABCB8 0 0 0 162 1 1
    NPC1 PARK2 0 0 212 212 1 1
    NPC1 BCDIN3D 0 0 301 301 1 1
    NPC1 ST3GAL4 0 0 46 417 1 1
    NPC1 LGMN 0 0 88 155 1 1
    NPC1 PLTP 0 0 211 211 1 1
    NPC1 FA2H 0 0 122 176 1 1
    NPC1 SCARB2 0 0 391 427 1 1
    NPC1 ABCC2 0 0 46 330 1 1
    NPC1 LMBR1L 270 0 0 270 1 1
    NPC1 B3GALT4 0 0 74 278 1 1
    NPC1 FAM57B 0 0 210 210 1 1
    NPC1 A4GALT 0 0 82 156 1 1
    NPC1 POR 0 0 0 294 1 1
    NPC1 B4GALNT1 0 0 647 647 1 1
    NPC1 SMPDL3A 0 0 75 207 1 1
    NPC1 SLC29A1 0 0 0 414 1 1
    NPC1 C9orf72 0 0 136 226 1 2
    NPC1 JPH3 0 0 74 161 1 1
    NPC1 SOAT1 0 0 392 435 1 1
    NPC1 LRP1B 0 0 147 170 1 1
    NPC1 CTSE 0 0 0 224 1 1
    NPC1 IL17RC 234 0 0 234 1 1
    NPC1 GOLPH3 0 0 180 179 1 1
    NPC1 VAMP4 0 0 181 268 1 1
    NPC1 SCUBE2 0 0 167 294 1 1
    NPC1 SLC26A11 0 0 166 196 1 1
    NPC1 VPS4B 0 0 465 465 1 1
    NPC1 GPR128 0 0 0 150 1 1
    NPC1 STK36 0 0 90 157 1 1
    NPC1 HMGCS1 0 0 324 380 1 1
    NPC1 NR1H2 0 0 207 345 1 1
    NPC1 INSIG1 0 0 370 422 1 1
    NPC1 LAMP1 0 0 652 691 1 2
    NPC1 OSBPL5 270 800 937 990 1 1
    NPC1 GRAMD1C 0 0 181 213 1 1
    NPC1 ACBD5 0 0 222 222 1 1
    NPC1 HTT 0 0 269 332 1 1
    NPC1 CLEC4G 0 0 310 448 1 1
    NPC1 EGFR 0 0 123 182 1 1
    NPC1 ABCB9 0 0 0 162 1 1
    NPC1 SPTLC1 0 0 134 177 1 1
    NPC1 PCSK5 0 0 45 176 1 1
    NPC1 RAB8A 0 0 235 248 1 2
    NPC1 MCOLN1 0 0 460 489 1 1
    NPC1 ARSB 0 0 154 206 1 2
    NPC1 B4GALT6 0 0 90 175 1 1
    NPC1 B3GALT5 0 0 67 232 1 1
    NPC1 RBMS1 0 0 46 199 1 1
    NPC1 PLEKHA8 0 0 210 211 1 1
    NPC1 VIPAS39 0 0 217 234 1 1
    NPC1 RBMS3 0 0 70 170 1 1
    NPC1 HDAC6 0 0 113 170 1 2
    NPC1 TSPAN31 0 0 0 162 1 1
    NPC1 CLU 0 0 425 425 1 2
    NPC1 OSTM1 0 0 118 206 1 1
    NPC1 RNF145 0 0 81 193 1 1
    NPC1 TMEM181 0 0 113 195 1 1
    NPC1 APP 0 0 405 455 1 1
    NPC1 C3AR1 0 0 63 156 1 1
    NPC1 PASK 0 0 0 232 1 1
    NPC1 TMEM240 0 0 170 189 1 1
    NPC1 PRRC2A 0 0 323 327 1 1
    NPC1 NEDD4 0 0 82 261 1 2
    NPC1 POSTN 0 0 0 159 1 1
    NPC1 UPK1B 0 0 0 155 1 1
    NPC1 CNPY4 0 0 108 243 1 1
    NPC1 F11 0 0 0 187 1 1
    NPC1 RAB5A 0 0 369 369 1 2
    NPC1 FAM166B 0 0 150 239 1 1
    NPC1 NR1H3 0 0 260 386 1 1
    NPC1 NDRG1 0 0 0 356 1 1
    NPC1 CD151 0 0 0 158 1 1
    NPC1 SYNDIG1 0 0 0 189 1 1
    NPC1 CTSL 0 0 468 481 1 1
    NPC1 KCNE1B 0 0 0 188 1 1
    NPC1 SLC1A7 0 0 125 212 1 1
    NPC1 PIK3C3 0 0 194 270 1 2
    NPC1 RBP5 0 0 154 166 1 1
    NPC1 TTC9 0 0 113 207 1 1
    NPC1 KLHL31 0 0 73 186 1 1
    NPC1 IQCG 0 0 123 196 1 1
    NPC1 FOLR1 0 0 141 241 1 1
    NPC1 TRA2A 0 0 66 564 1 1
    NPC1 PPP1R26 0 0 141 164 1 1
    NPC1 SCPEP1 0 0 108 151 1 1
    NPC1 GBGT1 0 0 182 219 1 1
    NPC1 SYVN1 0 0 73 188 1 1
    NPC1 PLEK 0 0 171 257 1 1
    NPC1 SPNS1 0 0 131 210 1 2
    NPC1 MTOR 0 0 218 251 1 2
    NPC1 GLA 0 0 457 490 1 1
    NPC1 FLAD1 0 0 90 328 1 1
    NPC1 KCNE1 0 0 0 188 1 1
    NPC1 FTO 0 0 505 505 1 1
    NPC1 NKTR 0 0 0 151 1 1
    NPC1 SLC38A9 0 0 643 651 1 1
    NPC1 ATP13A1 0 0 55 215 1 1
    NPC1 SC5D 0 0 183 216 1 1
    NPC1 PSAP 0 0 278 371 1 1
    NPC1 LPCAT1 0 0 57 194 1 1
    NPC1 IQGAP1 0 0 57 150 1 1
    NPC1 TSPAN11 0 0 0 158 1 1
    NPC1 FIG4 0 0 167 197 1 1
    NPC1 TPCN2 0 0 469 517 1 1
    NPC1 WWP1 270 0 0 309 1 1
    NPC1 STARD3NL 0 0 643 650 1 1
    NPC1 CLTCL1 0 0 102 176 1 1
    NPC1 PCTP 0 0 134 173 1 1
    NPC1 TMBIM4 0 0 67 207 1 1
    NPC1 GAPDH 0 0 259 372 1 2
    NPC1 ELOVL5 0 0 108 197 1 1
    NPC1 TCF7L2 0 0 150 203 1 1
    NPC1 ABL1 0 0 113 180 1 1
    NPC1 PTPLA 0 0 67 210 1 1
    NPC1 OSBPL3 0 0 90 230 1 1
    NPC1 TPCN1 0 0 203 260 1 1
    NPC1 FYCO1 0 0 142 173 1 2
    Ontologies
    ID Category Term Effect Evidence PubMed
    GO:0015485 Molecular Function cholesterol binding enables IBA
    GO:0015485 Molecular Function cholesterol binding enables IDA
    GO:0120020 Molecular Function cholesterol transfer activity enables IMP
    GO:0005515 Molecular Function protein binding enables IPI
    GO:0038023 Molecular Function signaling receptor activity enables TAS
    GO:0004888 Molecular Function transmembrane signaling receptor activity enables TAS
    GO:0001618 Molecular Function virus receptor activity enables IEA
    GO:0007628 Biological Process adult walking behavior involved_in IEA
    GO:0006914 Biological Process autophagy acts_upstream_of_or_within IGI
    GO:0008206 Biological Process bile acid metabolic process involved_in ISS
    GO:0071404 Biological Process cellular response to low-density lipoprotein particle stimulus involved_in IEA
    GO:0071383 Biological Process cellular response to steroid hormone stimulus involved_in IEA
    GO:0033344 Biological Process cholesterol efflux involved_in IDA
    GO:0042632 Biological Process cholesterol homeostasis involved_in IBA
    GO:0042632 Biological Process cholesterol homeostasis involved_in IDA
    GO:0042632 Biological Process cholesterol homeostasis involved_in IMP
    GO:0042632 Biological Process cholesterol homeostasis involved_in ISS
    GO:0008203 Biological Process cholesterol metabolic process involved_in IEA
    GO:0010878 Biological Process cholesterol storage involved_in IEA
    GO:0030301 Biological Process cholesterol transport involved_in IDA
    GO:2000900 Biological Process cyclodextrin metabolic process involved_in IEA
    GO:0006897 Biological Process endocytosis involved_in IEA
    GO:0090150 Biological Process establishment of protein localization to membrane involved_in IDA
    GO:0010467 Biological Process gene expression involved_in IEA
    GO:0030299 Biological Process intestinal cholesterol absorption involved_in IBA
    GO:0032367 Biological Process intracellular cholesterol transport involved_in IMP
    GO:0032365 Biological Process intracellular lipid transport involved_in IMP
    GO:0001889 Biological Process liver development involved_in IEA
    GO:0007041 Biological Process lysosomal transport involved_in ISS
    GO:0016236 Biological Process macroautophagy involved_in IEA
    GO:0031579 Biological Process membrane raft organization involved_in IMP
    GO:1904262 Biological Process negative regulation of TORC1 signaling involved_in IDA
    GO:1904036 Biological Process negative regulation of epithelial cell apoptotic process involved_in IEA
    GO:0016242 Biological Process negative regulation of macroautophagy involved_in IEA
    GO:0022008 Biological Process neurogenesis involved_in IEA
    GO:0012501 Biological Process programmed cell death involved_in IEA
    GO:0006486 Biological Process protein glycosylation involved_in IDA
    GO:0046686 Biological Process response to cadmium ion involved_in IEA
    GO:0009410 Biological Process response to xenobiotic stimulus involved_in IEA
    GO:0015918 Biological Process sterol transport involved_in IBA
    GO:0046718 Biological Process symbiont entry into host cell involved_in IMP
    GO:0005794 Cellular Component Golgi apparatus located_in IEA
    GO:0005783 Cellular Component endoplasmic reticulum located_in IDA
    GO:0070062 Cellular Component extracellular exosome located_in HDA
    GO:0005576 Cellular Component extracellular region located_in ISS
    GO:0031902 Cellular Component late endosome membrane located_in IMP
    GO:0005765 Cellular Component lysosomal membrane located_in HDA
    GO:0005765 Cellular Component lysosomal membrane located_in IDA
    GO:0005765 Cellular Component lysosomal membrane located_in IMP
    GO:0005765 Cellular Component lysosomal membrane located_in TAS
    GO:0005764 Cellular Component lysosome located_in ISS
    GO:0016020 Cellular Component membrane located_in HDA
    GO:0045121 Cellular Component membrane raft located_in IEA
    GO:0005635 Cellular Component nuclear envelope located_in IDA
    GO:0048471 Cellular Component perinuclear region of cytoplasm located_in IDA
    GO:0005886 Cellular Component plasma membrane is_active_in IBA
    GO:0005886 Cellular Component plasma membrane located_in IDA
    Pathways
    Name DB ID
    Plasma lipoprotein assembly, remodeling, and clearance Reactome R-HSA-174824
    Transport of small molecules Reactome R-HSA-382551
    LDL clearance Reactome R-HSA-8964038
    Plasma lipoprotein clearance Reactome R-HSA-8964043
    7-oxo-C and 7-beta-HC pathways (WP5064) WikiPathways WP5064_r120384
    Degradation pathway of sphingolipids, including diseases (WP4153) WikiPathways WP4153_r123688
    Ebola virus infection in host (WP4217) WikiPathways WP4217_r120623
    Transcripts
    Accession Version MolecularType Name NCBI Comments
    XM_005258279 3 mRNA transcript variant X3 NC_000018 Reference
    XM_005258277 1 mRNA transcript variant X1 NC_000018 Reference
    XM_017025787 2 mRNA transcript variant X8 NC_000018 Reference
    XM_006722479 4 mRNA transcript variant X5 NC_000018 Reference
    XM_047437539 1 mRNA transcript variant X9 NC_000018 Reference
    XM_017025786 2 mRNA transcript variant X7 NC_000018 Reference
    XM_017025785 1 mRNA transcript variant X6 NC_000018 Reference
    XM_017025784 1 mRNA transcript variant X4 NC_000018 Reference
    NM_000271 5 mRNA None NC_000018 Reference
    XM_005258278 6 mRNA transcript variant X2 NC_000018 Reference