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CISD2

CDGSH iron sulfur domain 2
General Information
Name CDGSH iron sulfur domain 2
Alias
  • CDGSH iron-sulfur domain-containing protein 2
  • endoplasmic reticulum intermembrane small protein
  • mitoNEET-related 1 protein
  • nutrient-deprivation autophagy factor-1
  • zinc finger, CDGSH-type domain 2
Gene_family CDGSH iron sulfur domain containing
organism Homo sapiens
entrez_id 493856
location 4q24
transcript_count 1
exon_count 3
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez The protein encoded by this gene is a zinc finger protein that localizes to the endoplasmic reticulum. The encoded protein binds an iron/sulfur cluster and may be involved in calcium homeostasis. Defects in this gene are a cause of Wolfram syndrome 2. [provided by RefSeq, Mar 2011]
    Stringdb CDGSH iron-sulfur domain-containing protein 2; Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy. Contributes to BIK-initiated autophagy, while it is not involved in BIK-dependent activation of caspases. Involved in life span control, probably via its function as regulator of autophagy; CDGSH iron sulfur domain containing
    nextProt Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmic reticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression of endoplasmic reticulum Ca(2+) stores during autophagy. Contributes to BIK-initiated autophagy, while it is not involved in BIK-dependent activation of caspases. Involved in life span control, probably via its function as regulator of autophagy.
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
CISD2 BioGRID ORF7a GeneID BioGRID Proximity Label-MS
CISD2 BioGRID ORF7b GeneID BioGRID Proximity Label-MS
CISD2 BioGRID ORF6 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID M GeneID BioGRID Proximity Label-MS
CISD2 BioGRID Rab18 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID TGOLN2 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID TBK1 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID RAB25 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID TRIM67 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID ADIPOR2 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID ORF1ab GeneID BioGRID Proximity Label-MS
CISD2 BioGRID PRKN GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID SAR1A GeneID BioGRID Proximity Label-MS
CISD2 BioGRID ARL1 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID ATG9A GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
CISD2 BioGRID TMED10 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID SEC61B GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
CISD2 BioGRID PGRMC1 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID COPB2 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID VAPA GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID VAPB GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID RAB7A GeneID BioGRID Proximity Label-MS
CISD2 BioGRID OSBP GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID DYNLL2 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID RTN4 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID CCDC47 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID SACM1L GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID COPE GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID HNRNPD GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID COPA GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID CAPZB GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID CANX GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID RHOD GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID RAC3 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID RAC2 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID CDC42 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID RHOG GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID RHOC GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID RHOA GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID TAX1BP1 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID SQSTM1 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID TMPRSS4 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID Nudt21 GeneID BioGRID Two-hybrid
CISD2 BioGRID Pcbp1 GeneID BioGRID Two-hybrid
CISD2 BioGRID LDLRAD1 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID LRRTM1 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID TMEM178A GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID TMEM106A GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID TSPAN10 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID C3orf52 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID CENPM GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID CRELD1 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID TMPRSS3 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID STIM2 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID PCDH10 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID MYORG GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID PBXIP1 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID TMEM63C GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID PCDHA4 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID PCDHAC1 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID PCDHB7 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID PCDHGC4 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID CISD1 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID SLC39A4 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID CHRNA9 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID IL17RB GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID ASIC4 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID PACC1 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID C3orf18 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID H2AP GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID SCAP GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID SLC27A2 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID KCNE3 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID TMEM63A GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID IL1R2 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID TLR3 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID PVR GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID MPL GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID LTBR GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID LRP3 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID KIR3DL2 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID KCNA2 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID HMOX2 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID HLA-C GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID NRG1 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID GRIN2A GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID GRIN1 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID SLC31A1 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID CHRND GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID CHRNB2 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID CHRNB1 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID CHRNA4 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID ATP1B1 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID STS GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID ADCY9 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID ATP2A1 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID ARF6 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID RAB35 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID CKAP4 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID BCAP31 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID RAB9A GeneID BioGRID Proximity Label-MS
CISD2 BioGRID STX7 GeneID BioGRID Proximity Label-MS; Two-hybrid
CISD2 BioGRID AKAP1 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID REEP5 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID TMPO GeneID BioGRID Proximity Label-MS
CISD2 BioGRID SEC62 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID STX4 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID STIM1 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID SSR1 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID RPN2 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID RPN1 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID RAB5C GeneID BioGRID Proximity Label-MS
CISD2 BioGRID RAB5A GeneID BioGRID Proximity Label-MS
CISD2 BioGRID RAB3B GeneID BioGRID Proximity Label-MS
CISD2 BioGRID PXMP2 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID LMNB1 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID LMNA GeneID BioGRID Proximity Label-MS
CISD2 BioGRID LAMP2 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID LAMP1 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID EMD GeneID BioGRID Proximity Label-MS; Two-hybrid
CISD2 BioGRID DHFR2 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID GJD3 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID LNPK GeneID BioGRID Proximity Label-MS
CISD2 BioGRID HSD3B7 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID DERL1 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID ELOVL5 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID ERGIC1 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID LRRC59 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID ERGIC2 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID HSD17B11 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID B3GAT1 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID LAMP3 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID TMT1A GeneID BioGRID Proximity Label-MS
CISD2 BioGRID PANX1 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID DNAJC25 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID DNAJC22 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID DNAJC1 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID DNAJC16 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID SEC63 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID Rnf183 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID MARCHF5 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID MTCH2 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID FKBP8 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID ST7 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID PTPN1 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID IMMP2L GeneID BioGRID Proximity Label-MS
CISD2 BioGRID C4orf3 GeneID BioGRID Two-hybrid
CISD2 BioGRID C14orf180 GeneID BioGRID Two-hybrid
CISD2 BioGRID SNORC GeneID BioGRID Two-hybrid
CISD2 BioGRID SMIM1 GeneID BioGRID Two-hybrid
CISD2 BioGRID SERP2 GeneID BioGRID Two-hybrid
CISD2 BioGRID RTP2 GeneID BioGRID Two-hybrid
CISD2 BioGRID TSPAN33 GeneID BioGRID Two-hybrid
CISD2 BioGRID YIPF6 GeneID BioGRID Two-hybrid
CISD2 BioGRID FAM241B GeneID BioGRID Two-hybrid
CISD2 BioGRID PLPP4 GeneID BioGRID Two-hybrid
CISD2 BioGRID VKORC1L1 GeneID BioGRID Two-hybrid
CISD2 BioGRID NRG4 GeneID BioGRID Two-hybrid
CISD2 BioGRID TMEM86A GeneID BioGRID Two-hybrid
CISD2 BioGRID GALNT15 GeneID BioGRID Two-hybrid
CISD2 BioGRID AQP10 GeneID BioGRID Two-hybrid
CISD2 BioGRID SLC35B4 GeneID BioGRID Two-hybrid
CISD2 BioGRID CFHR5 GeneID BioGRID Two-hybrid
CISD2 BioGRID THSD7B GeneID BioGRID Two-hybrid
CISD2 BioGRID CYBC1 GeneID BioGRID Two-hybrid
CISD2 BioGRID TMEM43 GeneID BioGRID Two-hybrid
CISD2 BioGRID TMEM243 GeneID BioGRID Two-hybrid
CISD2 BioGRID SLC13A3 GeneID BioGRID Two-hybrid
CISD2 BioGRID RUSF1 GeneID BioGRID Two-hybrid
CISD2 BioGRID PLPPR2 GeneID BioGRID Two-hybrid
CISD2 BioGRID NAPB GeneID BioGRID Two-hybrid
CISD2 BioGRID HHATL GeneID BioGRID Two-hybrid
CISD2 BioGRID POMGNT1 GeneID BioGRID Two-hybrid
CISD2 BioGRID CLN6 GeneID BioGRID Two-hybrid
CISD2 BioGRID AIG1 GeneID BioGRID Two-hybrid
CISD2 BioGRID PGAP2 GeneID BioGRID Two-hybrid
CISD2 BioGRID BMP10 GeneID BioGRID Two-hybrid
CISD2 BioGRID NSG1 GeneID BioGRID Two-hybrid
CISD2 BioGRID SEC22A GeneID BioGRID Two-hybrid
CISD2 BioGRID LRP10 GeneID BioGRID Two-hybrid
CISD2 BioGRID APOL2 GeneID BioGRID Two-hybrid
CISD2 BioGRID STX12 GeneID BioGRID Two-hybrid
CISD2 BioGRID LEPROTL1 GeneID BioGRID Two-hybrid
CISD2 BioGRID MAN2B2 GeneID BioGRID Two-hybrid
CISD2 BioGRID PNKP GeneID BioGRID Two-hybrid
CISD2 BioGRID CDIPT GeneID BioGRID Two-hybrid
CISD2 BioGRID BTN2A2 GeneID BioGRID Two-hybrid
CISD2 BioGRID BET1 GeneID BioGRID Two-hybrid
CISD2 BioGRID C2CD2L GeneID BioGRID Two-hybrid
CISD2 BioGRID GPR37L1 GeneID BioGRID Two-hybrid
CISD2 BioGRID CLDN10 GeneID BioGRID Two-hybrid
CISD2 BioGRID IER3 GeneID BioGRID Two-hybrid
CISD2 BioGRID VAMP4 GeneID BioGRID Two-hybrid
CISD2 BioGRID TMEM187 GeneID BioGRID Two-hybrid
CISD2 BioGRID TTPA GeneID BioGRID Two-hybrid
CISD2 BioGRID MIP GeneID BioGRID Two-hybrid
CISD2 BioGRID KIR2DL3 GeneID BioGRID Two-hybrid
CISD2 BioGRID GAST GeneID BioGRID Two-hybrid
CISD2 BioGRID EHHADH GeneID BioGRID Two-hybrid
CISD2 BioGRID BCL2L2 GeneID BioGRID Two-hybrid
CISD2 BioGRID LMBR1L GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID OTULINL GeneID BioGRID Proximity Label-MS
CISD2 BioGRID RHBDD1 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID CA9 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID VMP1 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID NRAS GeneID BioGRID Proximity Label-MS
CISD2 BioGRID KRAS GeneID BioGRID Proximity Label-MS
CISD2 BioGRID AGR2 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID ATXN3 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID COQ9 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID NDUFA4 GeneID BioGRID Affinity Capture-MS
CISD2 BioGRID TCTN2 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID TMEM216 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID TCTN3 GeneID BioGRID Proximity Label-MS
CISD2 BioGRID VDAC3 GeneID BioGRID Co-fractionation
CISD2 BioGRID VDAC2 GeneID BioGRID Co-fractionation
CISD2 BioGRID VDAC1 GeneID BioGRID Co-fractionation
CISD2 BioGRID COX4I1 GeneID BioGRID Co-fractionation
CISD2 BioGRID APP GeneID BioGRID Reconstituted Complex
CISD2 BioGRID SPP1 GeneID BioGRID Two-hybrid
CISD2 BioGRID BCL2 GeneID BioGRID Affinity Capture-Western
CISD2 BioGRID ELAVL1 GeneID BioGRID Affinity Capture-RNA
StringDB
A B experiments database textmining combined score hadb nhadb
CISD2 TXN 0 0 52 437 1 1
CISD2 CANX 312 0 413 580 1 2
CISD2 ALDH5A1 0 0 0 152 1 1
CISD2 NDUFB5 0 0 0 165 1 1
CISD2 C2orf47 274 0 0 301 1 1
CISD2 NUBP2 0 0 115 226 1 1
CISD2 CYC1 0 0 0 316 1 1
CISD2 ALMS1 0 0 256 272 1 1
CISD2 SGPP2 0 0 0 213 1 1
CISD2 NDUFA10 0 0 0 289 1 1
CISD2 TK2 0 0 0 185 1 1
CISD2 ATP5J 0 0 0 412 1 1
CISD2 SYCP3 0 0 71 283 1 1
CISD2 NT5DC3 0 0 233 403 1 1
CISD2 PPP2R5E 0 0 0 207 1 1
CISD2 BCL2 270 0 0 320 1 2
CISD2 HSD17B1 0 0 0 169 1 1
CISD2 BCAT2 0 0 133 240 1 1
CISD2 ENSG00000257921 0 0 0 273 1 1
CISD2 FAM132B 0 0 119 265 1 1
CISD2 SNX9 0 0 95 338 1 1
CISD2 PPT2 0 0 0 285 1 1
CISD2 ENSG00000260170 0 0 0 157 1 1
CISD2 HDAC7 0 0 82 289 1 1
CISD2 BAD 270 0 0 270 1 2
CISD2 PRPS2 0 0 0 283 1 1
CISD2 HSPA9 0 0 150 253 1 1
CISD2 ALAD 0 0 0 258 1 1
CISD2 PPP2R5C 0 0 96 370 1 1
CISD2 RTN4IP1 0 0 218 235 1 1
CISD2 SUV39H2 0 0 74 320 1 1
CISD2 UVRAG 0 0 218 218 1 2
CISD2 NDUFV1 0 0 88 446 1 1
CISD2 IREB2 0 0 123 357 1 1
CISD2 ATG4B 0 0 218 224 1 2
CISD2 CISD3 0 0 829 862 1 1
CISD2 ISCA2 0 0 95 285 1 1
CISD2 CD63 0 0 60 158 1 2
CISD2 IL1R2 135 0 0 154 1 1
CISD2 NR2C2AP 0 0 0 258 1 1
CISD2 KMT2A 0 0 53 199 1 1
CISD2 DGUOK 0 0 0 239 1 1
CISD2 ZNF451 0 0 0 265 1 1
CISD2 CD9 0 0 76 155 1 1
CISD2 ZNF512B 0 0 194 529 1 1
CISD2 IDH3A 0 0 0 358 1 1
CISD2 ENSG00000111780 0 0 0 176 1 1
CISD2 PDCD6IP 0 0 72 372 1 1
CISD2 FIS1 0 0 174 349 1 2
CISD2 ZFAND5 0 0 107 150 1 1
CISD2 C8orf37 0 0 169 169 1 1
CISD2 MDH1 0 0 0 169 1 1
CISD2 SLC13A1 0 0 245 259 1 1
CISD2 IDH3B 0 0 101 304 1 1
CISD2 C22orf29 0 0 325 325 1 1
CISD2 UQCRC1 0 0 0 268 1 1
CISD2 SLC19A1 0 0 83 450 1 1
CISD2 DCK 0 0 0 185 1 1
CISD2 TMEM167A 0 0 0 154 1 1
CISD2 TNNC2 0 0 107 168 1 1
CISD2 TJP2 0 0 0 216 1 1
CISD2 VAPB 0 0 72 153 1 1
CISD2 MCFD2 0 0 0 217 1 1
CISD2 ATF6 0 0 139 161 1 2
CISD2 LETM1 0 0 73 172 1 1
CISD2 ENSG00000144785 0 0 0 263 1 1
CISD2 CREB3L4 0 0 90 182 1 1
CISD2 DCTN5 0 0 182 358 1 1
CISD2 SPEN 0 0 391 390 1 1
CISD2 PARL 0 0 83 364 1 1
CISD2 EIF2B2 0 0 156 600 1 1
CISD2 TMED10 0 0 113 204 1 1
CISD2 VMP1 129 0 96 230 1 2
CISD2 SDHD 0 0 0 193 1 1
CISD2 NDUFA5 0 0 0 354 1 1
CISD2 CLPP 0 0 67 204 1 1
CISD2 GGT1 0 0 70 163 1 1
CISD2 AKT1 0 0 139 158 1 2
CISD2 UQCRFS1 0 0 0 420 1 1
CISD2 CA9 0 0 57 180 1 1
CISD2 ISCU 0 0 324 379 1 1
CISD2 WDTC1 0 0 0 150 1 1
CISD2 PCYOX1L 0 0 0 218 1 1
CISD2 NDUFB10 0 0 124 519 1 1
CISD2 YME1L1 0 0 204 252 1 1
CISD2 SQRDL 0 0 0 157 1 1
CISD2 AIFM1 0 0 122 506 1 1
CISD2 ITM2B 0 0 127 231 1 1
CISD2 SLC19A2 0 0 287 299 1 1
CISD2 HMGXB4 0 0 209 490 1 1
CISD2 PALM3 0 0 74 274 1 1
CISD2 NDOR1 0 0 416 543 1 1
CISD2 MYH4 0 0 123 156 1 1
CISD2 NDUFB3 0 0 0 257 1 1
CISD2 BIRC5 0 0 0 207 1 2
CISD2 PINK1 0 0 210 275 1 2
CISD2 NDUFB6 0 0 194 367 1 1
CISD2 ADRM1 0 0 0 188 1 1
CISD2 FDX1 0 0 134 184 1 1
CISD2 SLC25A5 0 0 0 199 1 1
CISD2 ATG3 0 0 218 218 1 2
CISD2 RABGEF1 0 0 90 232 1 1
CISD2 TESC 0 0 137 601 1 1
CISD2 S100A6 0 0 112 204 1 1
CISD2 EIF2AK3 0 0 159 158 1 2
CISD2 VDAC3 272 0 155 407 1 1
CISD2 MCU 0 0 218 234 1 2
CISD2 TIMM44 0 0 0 228 1 1
CISD2 MPHOSPH8 0 0 141 375 1 1
CISD2 VDAC1 272 0 210 435 1 2
CISD2 ATP5C1 0 0 0 223 1 1
CISD2 RAB28 0 0 134 166 1 1
CISD2 GORASP1 0 0 95 151 1 1
CISD2 PLLP 0 0 142 274 1 1
CISD2 SLC25A13 0 0 0 173 1 1
CISD2 PIGO 0 0 157 362 1 1
CISD2 NARFL 0 0 193 505 1 1
CISD2 ADORA2B 0 0 46 219 1 1
CISD2 BNIP3L 0 0 285 284 1 2
CISD2 TIMM8A 0 0 287 347 1 1
CISD2 NRG1 204 0 0 204 1 2
CISD2 ATP5H 0 0 0 611 1 1
CISD2 PDLIM3 0 0 99 164 1 1
CISD2 ASPN 0 0 0 217 1 1
CISD2 LAPTM4B 0 0 107 199 1 2
CISD2 MDH2 0 0 0 213 1 1
CISD2 LDHB 0 0 0 259 1 1
CISD2 MARCH5 117 0 186 352 1 1
CISD2 NUBP1 0 0 170 409 1 1
CISD2 DCAKD 0 0 240 239 1 1
CISD2 NKG7 0 0 82 173 1 1
CISD2 AICDA 0 0 47 165 1 1
CISD2 ATG4D 0 0 143 182 1 2
CISD2 ZNF638 0 0 165 333 1 1
CISD2 GABRB3 0 0 67 160 1 1
CISD2 HDAC11 0 0 53 215 1 1
CISD2 COX6A1 0 0 0 196 1 1
CISD2 HELLS 0 0 134 238 1 1
CISD2 SMARCA1 0 0 57 219 1 1
CISD2 MIEN1 0 0 0 318 1 1
CISD2 TMED1 0 0 70 206 1 1
CISD2 ATG12 0 0 208 208 1 2
CISD2 NDUFS8 0 0 0 154 1 1
CISD2 BOLA1 0 0 74 191 1 1
CISD2 GP5 0 0 81 326 1 1
CISD2 ATP1A2 0 0 0 201 1 1
CISD2 MPC2 0 0 0 186 1 1
CISD2 ENSG00000276418 0 0 156 196 1 1
CISD2 BLK 0 0 171 171 1 1
CISD2 LDHAL6B 0 0 0 230 1 1
CISD2 LTBR 196 0 0 196 1 1
CISD2 ATP5I 0 0 0 333 1 1
CISD2 HDAC1 0 0 74 156 1 2
CISD2 RAB42 0 0 231 396 1 1
CISD2 ACO1 0 0 321 502 1 1
CISD2 NFU1 0 0 81 205 1 1
CISD2 FLOT2 0 0 0 248 1 1
CISD2 RAB2B 0 0 134 219 1 1
CISD2 AKAP10 0 0 411 410 1 1
CISD2 ATG16L1 0 0 151 150 1 2
CISD2 PPAT 0 0 45 292 1 1
CISD2 CYS1 0 0 234 234 1 1
CISD2 FRMD7 0 0 181 181 1 1
CISD2 GID8 0 0 181 181 1 1
CISD2 NUBPL 0 0 48 167 1 1
CISD2 GNMT 0 0 89 216 1 1
CISD2 ISCA1 0 0 89 397 1 1
CISD2 AIFM3 0 0 0 229 1 1
CISD2 SLC25A46 0 0 166 197 1 1
CISD2 UEVLD 0 0 0 195 1 1
CISD2 ANAPC10 0 0 0 154 1 1
CISD2 SOD2 0 0 116 181 1 2
CISD2 TOP2B 0 0 81 192 1 1
CISD2 APOO 0 0 143 483 1 1
CISD2 RPS21 0 0 108 201 1 1
CISD2 FTH1 0 0 140 217 1 1
CISD2 AUH 0 0 143 161 1 1
CISD2 SLC25A28 0 0 193 214 1 1
CISD2 HSD17B14 0 0 60 216 1 1
CISD2 INTS8 0 0 171 535 1 1
CISD2 SGPP1 0 0 0 213 1 1
CISD2 PHB 0 0 69 175 1 1
CISD2 PTF1A 0 0 170 169 1 1
CISD2 SLC39A4 213 0 0 222 1 1
CISD2 CYB5R4 0 0 0 171 1 1
CISD2 NDUFA6 0 0 0 541 1 1
CISD2 BECN1 0 0 722 722 1 2
CISD2 PEX16 0 0 125 154 1 1
CISD2 FKBP9 0 0 0 207 1 1
CISD2 CD81 0 0 66 165 1 1
CISD2 GLIS3 0 0 194 209 1 1
CISD2 C14orf166 0 0 167 353 1 1
CISD2 LDHC 0 0 0 200 1 1
CISD2 RRAGD 0 0 166 280 1 1
CISD2 ADGB 0 0 0 188 1 1
CISD2 PARP2 0 0 60 316 1 1
CISD2 ATP1A1 0 0 67 222 1 1
CISD2 SLC40A1 0 0 60 279 1 1
CISD2 CALCOCO2 0 0 74 284 1 2
CISD2 ATG5 0 0 285 284 1 2
CISD2 KLF11 0 0 193 208 1 1
CISD2 PPT1 0 0 84 346 1 1
CISD2 PDIA5 0 0 0 237 1 1
CISD2 GBE1 0 0 91 339 1 1
CISD2 CAPNS1 0 0 112 173 1 2
CISD2 MANF 0 0 143 253 1 1
CISD2 HLA-C 231 0 0 230 1 1
CISD2 SIRT1 0 0 292 292 1 2
CISD2 CHCHD3 0 0 120 224 1 1
CISD2 MCL1 0 0 112 167 1 2
CISD2 HOMER1 0 0 53 188 1 1
CISD2 EMC7 0 0 186 489 1 1
CISD2 NSD1 0 0 60 455 1 1
CISD2 EHMT1 0 0 67 281 1 1
CISD2 AFG3L2 0 0 269 334 1 1
CISD2 CHKB 0 0 212 218 1 1
CISD2 RAC1 0 0 0 428 1 2
CISD2 GPX3 0 0 193 214 1 1
CISD2 SOD3 0 0 0 248 1 1
CISD2 GNPTG 0 0 155 154 1 1
CISD2 HINT1 0 0 129 222 1 1
CISD2 GPX1 0 0 143 184 1 1
CISD2 COQ3 0 0 0 167 1 1
CISD2 SETDB2 0 0 103 496 1 1
CISD2 SEC61B 0 0 124 233 1 1
CISD2 SEC22B 0 0 0 161 1 1
CISD2 PACSIN3 0 0 241 448 1 1
CISD2 ATG10 0 0 212 219 1 2
CISD2 NDUFA8 0 0 117 473 1 1
CISD2 PMPCB 0 0 0 268 1 1
CISD2 USP30 0 0 68 182 1 1
CISD2 URGCP 0 0 194 462 1 1
CISD2 DCAF15 0 0 195 524 1 1
CISD2 MDH1B 0 0 0 168 1 1
CISD2 DCAF17 0 0 324 426 1 1
CISD2 WDR43 0 0 165 399 1 1
CISD2 HMOX2 270 0 0 273 1 1
CISD2 TRIM46 0 0 139 160 1 1
CISD2 ATG7 0 0 268 268 1 2
CISD2 PRPS1 0 0 181 388 1 1
CISD2 RFX5 0 0 94 186 1 1
CISD2 NAMPT 0 0 62 230 1 2
CISD2 RPS3A 0 0 0 187 1 1
CISD2 SMIM14 0 0 247 391 1 1
CISD2 NDUFS2 0 0 0 348 1 1
CISD2 IL18RAP 0 0 0 189 1 1
CISD2 ATM 0 0 66 157 1 2
CISD2 TOMM70A 0 0 177 321 1 1
CISD2 UQCR11 0 0 0 165 1 1
CISD2 ATP5L 0 0 0 245 1 1
CISD2 LDHA 0 0 0 259 1 2
CISD2 EFHD2 0 0 134 152 1 1
CISD2 AMBRA1 0 0 370 370 1 2
CISD2 RHOT2 0 0 134 200 1 1
CISD2 APOOL 0 0 0 266 1 1
CISD2 TXNDC2 0 0 0 239 1 1
CISD2 ABCB7 0 0 67 160 1 1
CISD2 DNAJC11 0 0 180 309 1 1
CISD2 BUB3 0 0 67 160 1 1
CISD2 GABARAP 0 0 160 159 1 2
CISD2 TIMM23B 0 0 0 154 1 1
CISD2 VDAC2 272 0 143 399 1 1
CISD2 AATF 0 0 65 209 1 1
CISD2 SLC9B2 0 0 163 307 1 1
CISD2 PMPCA 0 0 0 190 1 1
CISD2 GLRX5 0 0 95 172 1 1
CISD2 NDUFS1 0 0 81 339 1 1
CISD2 PAX4 0 0 166 165 1 1
CISD2 RAX2 0 0 161 161 1 1
CISD2 HSCB 0 0 261 341 1 1
CISD2 HDAC6 0 0 123 229 1 2
CISD2 PPP2R5D 0 0 108 378 1 1
CISD2 HDAC2 0 0 306 321 1 1
CISD2 SLC25A4 0 0 135 277 1 1
CISD2 RPS16 0 0 0 150 1 1
CISD2 PYROXD1 0 0 0 157 1 1
CISD2 DUOXA2 0 0 112 482 1 1
CISD2 TIMM23 0 0 0 186 1 1
CISD2 CHCHD2 0 0 112 222 1 1
CISD2 KIF5C 0 0 95 235 1 1
CISD2 LEPROT 0 0 58 263 1 1
CISD2 PRPSAP1 0 0 0 169 1 1
CISD2 GPM6B 0 0 122 212 1 1
CISD2 CFTR 0 0 328 328 1 2
CISD2 CYB5D1 0 0 0 169 1 1
CISD2 CYB5A 0 0 0 200 1 1
CISD2 BOLA2 0 0 210 256 1 1
CISD2 RB1CC1 0 0 162 161 1 2
CISD2 EHMT2 0 0 0 303 1 2
CISD2 BACH2 0 0 74 280 1 1
CISD2 LNPEP 0 0 96 573 1 1
CISD2 FAM96B 0 0 157 175 1 1
CISD2 LMBR1L 270 0 0 270 1 1
CISD2 GCDH 0 0 124 349 1 1
CISD2 HSD17B10 0 0 91 471 1 1
CISD2 NDUFB7 0 0 0 307 1 1
CISD2 TAX1BP1 0 0 49 239 1 2
CISD2 FXN 0 0 261 352 1 1
CISD2 NDUFS3 0 0 53 335 1 1
CISD2 SCG5 0 0 357 357 1 1
CISD2 HDAC3 0 0 411 415 1 2
CISD2 RP1L1 0 0 181 198 1 1
CISD2 COX7A2 0 0 0 161 1 1
CISD2 TSFM 0 0 113 676 1 1
CISD2 NDFIP2 0 0 143 328 1 1
CISD2 ZFP57 0 0 261 274 1 1
CISD2 YTHDF2 0 0 330 330 1 1
CISD2 P4HB 0 0 112 167 1 2
CISD2 ENSG00000261832 0 0 89 182 1 1
CISD2 ATP5G3 0 0 0 210 1 1
CISD2 NDUFC1 0 0 0 223 1 1
CISD2 TPK1 0 0 140 326 1 1
CISD2 FA2H 0 0 0 169 1 1
CISD2 ANKRD28 0 0 150 339 1 1
CISD2 CYP51A1 0 0 66 436 1 1
CISD2 SLC25A12 0 0 108 298 1 1
CISD2 IDH3G 0 0 0 348 1 1
CISD2 WFS1 0 0 880 902 1 1
CISD2 WDPCP 0 0 154 153 1 1
CISD2 DUOXA1 0 0 0 254 1 1
CISD2 PARK2 0 0 165 179 1 1
CISD2 NDUFS6 0 0 0 178 1 1
CISD2 ST3GAL4 0 0 0 302 1 1
CISD2 FKBP8 117 0 157 446 1 1
CISD2 HDAC10 0 0 88 380 1 1
CISD2 ATP5L2 0 0 0 228 1 1
CISD2 CCDC91 0 0 157 287 1 1
CISD2 ATG14 0 0 218 218 1 2
CISD2 LARS2 0 0 82 283 1 1
CISD2 NDUFV2 0 0 94 231 1 1
CISD2 COX5B 0 0 0 251 1 1
CISD2 SPDL1 0 0 113 422 1 1
CISD2 BCL2L1 0 0 141 210 1 2
CISD2 PIK3R4 0 0 181 181 1 2
CISD2 GJB6 0 0 306 306 1 1
CISD2 SSBP2 0 0 125 260 1 1
CISD2 PDHA1 0 0 0 271 1 1
CISD2 NDUFA12 0 0 0 172 1 1
CISD2 CIAPIN1 0 0 635 696 1 1
CISD2 PPP2R2A 0 0 75 225 1 1
CISD2 SIRT2 0 0 384 397 1 2
CISD2 PRDX6 0 0 90 569 1 1
CISD2 FGF21 0 0 134 167 1 2
CISD2 CS 0 0 0 273 1 1
CISD2 SLC25A6 0 0 0 199 1 1
CISD2 WHSC1 0 0 0 250 1 1
CISD2 ZFC3H1 0 0 204 477 1 1
CISD2 SSBP3 0 0 0 189 1 1
CISD2 GCSH 0 0 0 189 1 1
CISD2 BTF3L4 0 0 87 196 1 1
CISD2 PDHA2 0 0 0 261 1 1
CISD2 UBE2D3 0 0 181 216 1 1
CISD2 ACO2 0 0 233 489 1 1
CISD2 GPR179 0 0 170 169 1 1
CISD2 ST7 226 0 0 244 1 1
CISD2 ATP5E 0 0 67 189 1 1
CISD2 ATP1A3 0 0 91 298 1 1
CISD2 SFXN4 0 0 218 709 1 1
CISD2 BATF2 0 0 113 208 1 1
CISD2 CXXC4 0 0 113 211 1 1
CISD2 LDHAL6A 0 0 0 230 1 1
CISD2 PIK3C3 0 0 338 338 1 2
CISD2 GOLGA8A 0 0 231 230 1 1
CISD2 CXorf57 0 0 205 554 1 1
CISD2 PDCD5 0 0 116 181 1 1
CISD2 OPA3 0 0 416 677 1 1
CISD2 RAB17 0 0 113 201 1 1
CISD2 LIAS 0 0 125 232 1 1
CISD2 COQ9 245 0 0 422 1 1
CISD2 MRFAP1 0 0 205 685 1 1
CISD2 PNPT1 0 0 95 288 1 1
CISD2 GIMAP5 0 0 856 856 1 1
CISD2 MFN2 0 0 325 340 1 2
CISD2 DCAF6 0 0 0 150 1 1
CISD2 CLN3 0 0 157 243 1 2
CISD2 PPP2R2D 0 0 0 197 1 1
CISD2 BOLA3 0 0 53 150 1 1
CISD2 MTPAP 0 0 218 552 1 1
CISD2 UQCRC2 0 0 0 301 1 1
CISD2 VRK1 0 0 95 360 1 1
CISD2 CINP 0 0 246 440 1 1
CISD2 COX4I1 680 0 0 706 1 1
CISD2 SUV39H1 0 0 46 191 1 1
CISD2 RAB29 0 0 0 220 1 1
CISD2 MUL1 0 0 216 247 1 2
CISD2 SGPL1 0 0 74 157 1 1
CISD2 METAP1D 0 0 0 188 1 1
CISD2 HDAC4 0 0 75 188 1 2
CISD2 PDIA2 0 0 0 200 1 1
CISD2 SQSTM1 0 0 181 181 1 2
CISD2 BNIP3 0 0 291 290 1 2
CISD2 SIRT3 0 0 69 255 1 2
CISD2 HSPE1 0 0 0 453 1 1
CISD2 NLRX1 0 0 0 171 1 2
CISD2 GTSE1 0 0 103 302 1 1
CISD2 SPG7 0 0 264 587 1 1
CISD2 NDUFB11 0 0 135 309 1 1
CISD2 TMEM109 0 0 210 369 1 1
CISD2 INS 0 0 245 244 1 2
CISD2 ATG13 0 0 154 153 1 2
CISD2 WHSC1L1 0 0 0 250 1 1
CISD2 PGAM2 0 0 94 150 1 1
CISD2 FAM208A 0 0 213 237 1 1
CISD2 IMMP2L 63 0 0 153 1 1
CISD2 BANK1 0 0 89 183 1 1
CISD2 IER3IP1 0 0 391 420 1 1
CISD2 SPP1 192 0 47 197 1 2
CISD2 MTX1 0 0 174 262 1 1
CISD2 CRTAM 0 0 112 251 1 1
CISD2 NFS1 0 0 201 385 1 1
CISD2 TUBGCP4 0 0 157 156 1 1
CISD2 CKM 0 0 101 155 1 1
CISD2 MNT 0 0 567 567 1 1
CISD2 SOD1 0 0 0 710 1 2
CISD2 CENPE 0 0 76 151 1 1
CISD2 RABL2A 0 0 181 188 1 1
CISD2 COX6C 0 0 0 169 1 1
CISD2 PPHLN1 0 0 181 486 1 1
CISD2 CAPN2 0 0 183 188 1 2
CISD2 ZNF513 0 0 160 175 1 1
CISD2 NDUFB2 0 0 74 160 1 1
CISD2 TFAM 0 0 96 269 1 2
CISD2 CYB5B 0 0 0 222 1 1
CISD2 MFN1 0 0 170 189 1 2
CISD2 B3GNT6 0 0 0 153 1 1
CISD2 BIK 0 0 293 293 1 2
CISD2 FUNDC1 0 0 150 173 1 2
CISD2 CALR 0 0 122 154 1 1
CISD2 MANBA 0 0 324 339 1 1
CISD2 SLC25A31 0 0 0 199 1 1
CISD2 DHRS11 0 0 74 244 1 1
CISD2 PRPSAP2 0 0 0 173 1 1
CISD2 USP35 0 0 48 235 1 1
CISD2 HSPB9 0 0 57 156 1 1
CISD2 ACRV1 273 0 0 273 1 1
CISD2 ITPR3 0 0 380 402 1 1
CISD2 RHOT1 0 0 108 208 1 1
CISD2 ZNF132 0 0 81 163 1 1
CISD2 DAPK1 0 0 150 305 1 2
CISD2 VPS37C 0 0 181 306 1 1
CISD2 NDUFAB1 0 0 0 392 1 1
CISD2 PEX11B 0 0 142 164 1 1
CISD2 CETP 0 0 295 295 1 1
CISD2 HSPE1-MOB4 0 0 0 269 1 1
CISD2 MIEF1 0 0 92 234 1 1
CISD2 C12orf65 0 0 406 440 1 1
CISD2 PRPS1L1 0 0 194 397 1 1
CISD2 GTF3C6 0 0 92 187 1 1
CISD2 SMARCA5 0 0 0 254 1 1
CISD2 ATP5A1 0 0 0 277 1 1
CISD2 HGSNAT 0 0 154 153 1 1
CISD2 GAK 0 0 0 188 1 1
CISD2 ITPR1 0 0 778 787 1 2
CISD2 AIFM2 0 0 0 198 1 1
CISD2 CYCS 312 0 134 392 1 2
CISD2 OGG1 0 0 48 216 1 1
CISD2 CIAO1 0 0 193 469 1 1
CISD2 ELOVL1 0 0 193 193 1 1
CISD2 IMMT 0 0 124 185 1 1
CISD2 GLRX3 0 0 151 232 1 1
CISD2 RAB38 0 0 0 166 1 1
CISD2 COX6A2 0 0 0 533 1 1
CISD2 NISCH 0 0 107 299 1 1
CISD2 MAPK8 0 0 123 162 1 2
CISD2 GLUD1 0 0 156 155 1 1
CISD2 LYRM5 0 0 81 232 1 1
CISD2 OSTC 0 0 0 173 1 1
CISD2 OTUB1 0 0 74 236 1 1
CISD2 NDUFS7 0 0 0 336 1 1
CISD2 EMC2 0 0 0 173 1 1
CISD2 NDUFS5 0 0 0 334 1 1
CISD2 ATP2A1 0 0 160 182 1 1
CISD2 KIF20A 0 0 102 264 1 1
CISD2 NIT2 0 0 57 272 1 1
CISD2 CCNB3 0 0 96 235 1 1
CISD2 FECH 0 0 51 269 1 1
CISD2 BDH2 0 0 239 267 1 1
CISD2 ABCC8 0 0 155 154 1 1
CISD2 CDK2AP1 0 0 108 183 1 1
CISD2 PFDN5 0 0 0 161 1 1
CISD2 BOLA2B 0 0 210 256 1 1
CISD2 PPP2R5A 0 0 94 428 1 1
CISD2 VPS35 0 0 74 285 1 2
CISD2 TMEM126A 0 0 402 423 1 1
CISD2 RAB32 0 0 0 166 1 2
CISD2 SPCS1 0 0 0 157 1 1
CISD2 AKTIP 0 0 120 254 1 1
CISD2 CERS2 0 0 0 187 1 1
CISD2 HDAC8 0 0 607 610 1 1
CISD2 SAMM50 0 0 108 299 1 1
CISD2 NDUFA4 275 0 0 337 1 1
CISD2 B3GNT3 0 0 124 227 1 1
CISD2 ADCY5 0 0 82 172 1 1
CISD2 RFX6 0 0 256 256 1 1
CISD2 MRPL10 0 0 66 185 1 1
CISD2 CHRNA9 227 0 0 226 1 1
CISD2 METAP1 0 0 0 219 1 1
CISD2 MMS19 0 0 113 486 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0051537 Molecular Function 2 iron, 2 sulfur cluster binding enables IBA
GO:0051537 Molecular Function 2 iron, 2 sulfur cluster binding enables IDA
GO:0003723 Molecular Function RNA binding enables HDA
GO:0046872 Molecular Function metal ion binding enables IEA
GO:0005515 Molecular Function protein binding enables IPI
GO:0042803 Molecular Function protein homodimerization activity enables IDA
GO:0000422 Biological Process autophagy of mitochondrion involved_in IBA
GO:0010506 Biological Process regulation of autophagy involved_in IMP
GO:0005783 Cellular Component endoplasmic reticulum located_in IDA
GO:0005789 Cellular Component endoplasmic reticulum membrane located_in IDA
GO:0016020 Cellular Component membrane located_in HDA
GO:0005741 Cellular Component mitochondrial outer membrane is_active_in IBA
GO:0005741 Cellular Component mitochondrial outer membrane located_in ISS
GO:0097038 Cellular Component perinuclear endoplasmic reticulum located_in IDA
GO:0032991 Cellular Component protein-containing complex part_of IDA
Pathways
Name DB ID
Transcripts
Accession Version MolecularType Name NCBI Comments
NM_001008388 5 mRNA None NC_000004 Reference