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TLR7

toll like receptor 7
General Information
Name toll like receptor 7
Alias
  • toll-like receptor 7
  • toll-like receptor 7-like
Gene_family Toll like receptors
organism Homo sapiens
entrez_id 51284
location Xp22.2
transcript_count 1
exon_count 3
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. The human TLR family comprises 11 members. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. For the recognition of structural components in foreign microorganisms, the various TLRs exhibit different patterns of expression as well; in this way for example, TLR-3, -7, and -8 are essential in the recognition of single-stranded RNA viruses. TLR7 senses single-stranded RNA oligonucleotides containing guanosine- and uridine-rich sequences from RNA viruses, a recognition occuring in the endosomes of plasmacytoid dendritic cells and B cells. This gene is predominantly expressed in lung, placenta, and spleen, and is phylogenetically related and lies in close proximity to another family member, TLR8, on chromosome X. [provided by RefSeq, Aug 2020]
    Stringdb Toll-like receptor 7; Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity)
    nextProt Endosomal receptor that plays a key role in innate and adaptive immunity (PubMed:14976261, PubMed:32433612). Controls host immune response against pathogens through recognition of uridine-containing single strand RNAs (ssRNAs) of viral origin or guanosine analogs (PubMed:31608988, PubMed:27742543, PubMed:12738885, PubMed:32706371). Upon binding to agonists, undergoes dimerization that brings TIR domains from the two molecules into direct contact, leading to the recruitment of TIR-containing downstream adapter MYD88 through homotypic interaction (PubMed:27742543). In turn, the Myddosome signaling complex is formed involving IRAK4, IRAK1, TRAF6, TRAF3 leading to activation of downstream transcription factors NF-kappa-B and IRF7 to induce pro-inflammatory cytokines and interferons, respectively (PubMed:27742543, PubMed:32706371).
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
TLR7 BioGRID SPPL3 GeneID BioGRID Positive Genetic
TLR7 BioGRID RNF115 GeneID BioGRID Affinity Capture-Western
TLR7 BioGRID A2ML1 GeneID BioGRID Affinity Capture-MS
TLR7 BioGRID SDR9C7 GeneID BioGRID Affinity Capture-MS
TLR7 BioGRID ALOXE3 GeneID BioGRID Affinity Capture-MS
TLR7 BioGRID EPDR1 GeneID BioGRID Affinity Capture-MS
TLR7 BioGRID DNAJB9 GeneID BioGRID Affinity Capture-MS
TLR7 BioGRID HAL GeneID BioGRID Affinity Capture-MS
TLR7 BioGRID GRAMD1A GeneID BioGRID Two-hybrid
TLR7 BioGRID MYD88 GeneID BioGRID Two-hybrid
TLR7 Protein MYD88 GeneID HPRD
StringDB
A B experiments database textmining combined score hadb nhadb
TLR7 IL12RB2 0 0 150 177 1 1
TLR7 TYR 0 0 181 181 1 2
TLR7 TRIM5 0 0 406 455 1 1
TLR7 POTEJ 0 0 0 156 1 1
TLR7 SNRPN 0 0 92 215 1 1
TLR7 SNRPD2 0 0 49 161 1 1
TLR7 CLEC17A 0 0 0 202 1 1
TLR7 PPIB 0 0 77 166 1 1
TLR7 CX3CR1 0 0 427 462 1 1
TLR7 XCR1 0 0 402 433 1 1
TLR7 PMEL 0 0 349 349 1 1
TLR7 LRMP 0 0 0 228 1 1
TLR7 TBC1D9B 0 0 0 155 1 1
TLR7 MRPS5 0 0 0 185 1 1
TLR7 LUC7L2 0 0 0 183 1 1
TLR7 DEFB103B 0 0 301 301 1 1
TLR7 MAPK9 0 0 107 159 1 2
TLR7 PLK2 0 0 0 165 1 1
TLR7 NRP1 0 0 459 459 1 1
TLR7 RPS6KA3 0 0 101 212 1 1
TLR7 ATG4A 0 0 0 155 1 2
TLR7 CASP9 0 0 155 180 1 2
TLR7 ARL11 0 0 0 193 1 1
TLR7 NLRP5 0 0 91 188 1 1
TLR7 ETS1 0 0 209 215 1 1
TLR7 NRXN2 0 0 0 153 1 1
TLR7 MS4A7 0 0 0 171 1 1
TLR7 IL17A 0 0 653 655 1 2
TLR7 BCL11A 0 0 141 189 1 1
TLR7 MAGEA3 0 0 241 240 1 2
TLR7 MOB1A 0 0 0 154 1 1
TLR7 ARG1 0 0 373 373 1 2
TLR7 AURKB 0 0 0 155 1 1
TLR7 ADIPOQ 0 0 143 191 1 2
TLR7 IGHV4-38-2 0 0 323 323 1 1
TLR7 C5AR2 0 0 132 154 1 1
TLR7 CD79B 0 0 211 344 1 1
TLR7 HLA-DQA1 0 0 267 354 1 1
TLR7 HIST2H3PS2 0 0 162 175 1 1
TLR7 IFIH1 0 0 804 835 1 1
TLR7 DNASE2 0 0 170 169 1 1
TLR7 CXorf38 0 0 0 151 1 1
TLR7 KLRF1 0 0 95 173 1 1
TLR7 IL2RG 0 0 260 581 1 1
TLR7 PRF1 0 0 466 486 1 1
TLR7 NR3C1 0 0 156 185 1 1
TLR7 MX2 0 0 391 473 1 1
TLR7 CISH 0 0 391 400 1 1
TLR7 CD244 0 0 142 271 1 1
TLR7 RCSD1 0 0 0 178 1 1
TLR7 CSK 0 0 97 204 1 1
TLR7 FLG 0 0 170 200 1 1
TLR7 IFNA10 0 0 185 185 1 1
TLR7 HNRNPA2B1 0 0 131 223 1 1
TLR7 HTR7 0 0 61 162 1 1
TLR7 DPP4 0 0 134 212 1 1
TLR7 ABCA1 0 0 160 191 1 2
TLR7 CUL5 0 0 96 182 1 1
TLR7 CCL4 0 0 556 647 1 1
TLR7 CEACAM1 0 0 150 168 1 1
TLR7 IL1A 0 0 556 566 1 1
TLR7 MAVS 0 0 703 748 1 2
TLR7 AIM2 0 0 602 629 1 2
TLR7 DDX58 0 0 843 865 1 1
TLR7 C4B 0 0 233 285 1 1
TLR7 YWHAG 0 0 0 161 1 1
TLR7 CCR10 0 0 154 153 1 1
TLR7 DEFB4B 0 0 298 298 1 1
TLR7 MFGE8 0 0 182 181 1 1
TLR7 PTPRJ 0 0 66 171 1 1
TLR7 DDX55 0 0 0 167 1 1
TLR7 TRIM21 0 0 392 414 1 1
TLR7 IL9 0 0 323 327 1 1
TLR7 TROVE2 0 0 560 560 1 1
TLR7 SERPINB1 0 0 49 220 1 1
TLR7 MLLT4 0 0 150 198 1 1
TLR7 TNFRSF10A 0 0 240 240 1 1
TLR7 PPEF1 0 0 95 307 1 1
TLR7 IFI44L 0 0 244 271 1 1
TLR7 TSSC4 0 0 140 272 1 1
TLR7 ROBO3 0 0 0 249 1 1
TLR7 KNG1 0 0 139 157 1 1
TLR7 LRRFIP1 0 0 292 336 1 1
TLR7 RC3H1 0 0 233 232 1 1
TLR7 CASP8 0 0 370 406 1 2
TLR7 IGLL5 0 0 138 188 1 1
TLR7 IFNE 0 0 103 163 1 1
TLR7 CD276 0 0 558 558 1 1
TLR7 AOAH 0 0 88 167 1 1
TLR7 ITGB1 0 0 123 248 1 1
TLR7 TNFAIP8L2 0 0 95 180 1 1
TLR7 NYX 0 0 0 151 1 1
TLR7 IL3 0 0 418 418 1 1
TLR7 NHS 0 0 0 183 1 1
TLR7 PRPF40B 0 0 0 273 1 1
TLR7 CEBPA 0 0 162 183 1 1
TLR7 LAIR1 0 0 175 271 1 1
TLR7 SLAMF6 0 0 204 257 1 1
TLR7 MYO1G 0 0 0 290 1 1
TLR7 INS 0 0 285 284 1 2
TLR7 ACTB 0 0 503 563 1 2
TLR7 NEU1 0 0 103 188 1 1
TLR7 FPR2 0 0 262 298 1 1
TLR7 CD8B 0 0 113 155 1 1
TLR7 LSM6 0 0 0 154 1 1
TLR7 ITGB7 0 0 90 209 1 1
TLR7 CD40 0 0 853 864 1 2
TLR7 RPS6KA6 0 0 0 155 1 1
TLR7 B2M 0 0 294 337 1 1
TLR7 PAX5 0 0 181 241 1 1
TLR7 GLI3 0 0 143 159 1 1
TLR7 FCGR2B 0 0 520 592 1 1
TLR7 RAB24 0 0 0 153 1 2
TLR7 TNFRSF14 0 0 161 209 1 1
TLR7 CA5B 0 0 0 154 1 1
TLR7 HSPA8 0 0 125 238 1 2
TLR7 UBE2L3 0 0 134 150 1 1
TLR7 EPCAM 0 0 180 231 1 2
TLR7 RHOA 0 0 138 213 1 2
TLR7 TLR5 0 0 870 402 1 1
TLR7 KLRK1 0 0 372 411 1 1
TLR7 CD3D 0 0 108 184 1 1
TLR7 IL36A 0 0 155 207 1 1
TLR7 UBE2N 0 900 275 926 1 1
TLR7 CXCL12 0 0 392 392 1 2
TLR7 ZRSR2 0 0 0 181 1 1
TLR7 RHOG 0 0 57 177 1 1
TLR7 MLKL 0 0 160 227 1 2
TLR7 SART1 0 0 0 177 1 1
TLR7 CD160 0 0 150 239 1 1
TLR7 FYB 0 0 81 538 1 1
TLR7 MS4A1 0 0 74 207 1 1
TLR7 IL22 0 0 324 331 1 1
TLR7 CD24 0 0 261 261 1 2
TLR7 CTAG1B 0 0 380 380 1 1
TLR7 GPR84 0 0 95 198 1 1
TLR7 ZMAT2 0 0 0 173 1 1
TLR7 PTPRN 0 0 48 155 1 1
TLR7 ADORA2A 0 0 289 288 1 1
TLR7 UNC93B1 0 600 988 995 1 1
TLR7 GABARAPL1 0 0 171 171 1 2
TLR7 OCA2 0 0 141 160 1 1
TLR7 CCRL2 0 0 391 432 1 1
TLR7 LAMP2 0 0 208 274 1 2
TLR7 IL17RA 0 0 321 344 1 1
TLR7 PRPF40A 0 0 0 161 1 1
TLR7 CD37 0 0 134 203 1 1
TLR7 SNAPC4 0 0 0 171 1 1
TLR7 YWHAE 0 0 81 195 1 1
TLR7 RPL4 0 0 0 163 1 1
TLR7 LCK 0 0 232 340 1 1
TLR7 CYSLTR1 0 0 94 238 1 1
TLR7 TICAM1 0 0 661 674 1 2
TLR7 LAMP3 0 0 235 278 1 1
TLR7 CD69 0 0 517 548 1 1
TLR7 RTP4 0 0 127 183 1 1
TLR7 PHF5A 0 0 0 174 1 1
TLR7 DNAJC3 0 0 306 344 1 1
TLR7 P2RY12 0 0 101 156 1 1
TLR7 CCR5 0 0 556 662 1 1
TLR7 IL37 0 0 142 233 1 1
TLR7 CALR 0 0 303 324 1 1
TLR7 MCOLN2 0 0 150 192 1 1
TLR7 CD8A 0 0 736 752 1 1
TLR7 APOBEC3A 0 0 213 258 1 1
TLR7 SIGLEC7 0 0 100 244 1 1
TLR7 FCRLA 0 0 108 151 1 1
TLR7 HAVCR2 0 0 391 463 1 1
TLR7 PSMB8 0 0 170 189 1 1
TLR7 SLAMF1 0 0 293 357 1 1
TLR7 MMP2 0 0 182 181 1 2
TLR7 IL1RAPL2 0 0 141 174 1 1
TLR7 RIPK2 0 0 382 412 1 2
TLR7 IL22RA2 0 0 157 160 1 1
TLR7 TNFSF4 0 0 425 424 1 1
TLR7 CCR3 0 0 258 345 1 1
TLR7 CASP1 0 0 645 705 1 2
TLR7 SNCA 0 0 158 171 1 2
TLR7 CXCL6 0 0 124 376 1 1
TLR7 CD27 0 0 468 494 1 1
TLR7 CD74 0 0 396 496 1 1
TLR7 MAP2K3 0 0 146 178 1 1
TLR7 PLK5 0 0 0 165 1 1
TLR7 FFAR2 0 0 139 170 1 1
TLR7 HSPA1A 0 0 205 337 1 1
TLR7 GBP4 0 0 153 232 1 1
TLR7 HLA-DRB1 0 0 181 250 1 1
TLR7 MST4 0 0 0 182 1 1
TLR7 ZFP36 0 0 156 171 1 1
TLR7 TNFSF10 0 0 401 422 1 2
TLR7 LUC7L 0 0 0 183 1 1
TLR7 SERPINA1 0 0 150 171 1 2
TLR7 CCL24 0 0 180 237 1 1
TLR7 SIGLEC1 0 0 392 471 1 1
TLR7 IL10RA 0 0 369 467 1 1
TLR7 BCL2L11 0 0 193 230 1 2
TLR7 ABCA10 0 0 0 177 1 1
TLR7 TMEM173 0 0 452 463 1 1
TLR7 AURKC 0 0 0 155 1 1
TLR7 BATF 0 0 158 228 1 1
TLR7 ATG14 0 0 161 161 1 2
TLR7 TNFRSF25 0 0 212 212 1 1
TLR7 DNASE1 0 0 180 179 1 1
TLR7 TRIAP1 0 0 150 173 1 1
TLR7 TLR4 0 0 941 716 1 2
TLR7 EMR1 0 0 73 342 1 1
TLR7 NOS2 0 0 290 323 1 2
TLR7 POTEE 0 0 0 156 1 1
TLR7 CD14 0 0 177 413 1 1
TLR7 FCGBP 0 0 0 156 1 1
TLR7 SNW1 0 0 0 248 1 1
TLR7 SNRPG 0 0 0 232 1 1
TLR7 NMI 0 0 117 157 1 1
TLR7 GAPT 0 0 73 163 1 1
TLR7 GABARAPL2 0 0 170 169 1 2
TLR7 CYSLTR2 0 0 68 193 1 1
TLR7 PHRF1 0 0 181 181 1 1
TLR7 CLEC7A 0 0 634 677 1 1
TLR7 LONRF2 0 0 0 199 1 1
TLR7 ENSG00000250349 0 0 184 183 1 1
TLR7 TAB3 0 0 318 420 1 1
TLR7 ACKR4 0 0 161 161 1 1
TLR7 KITLG 0 0 171 171 1 1
TLR7 TMEM203 0 0 74 151 1 1
TLR7 SF3B5 0 0 0 179 1 1
TLR7 PINLYP 0 0 0 512 1 1
TLR7 MYO1D 0 0 0 224 1 1
TLR7 BCL2L1 0 0 270 270 1 2
TLR7 AOC3 0 0 306 306 1 1
TLR7 CCL4L1 0 0 421 494 1 1
TLR7 NTNG2 0 0 0 167 1 1
TLR7 C1R 0 0 134 174 1 1
TLR7 HMGB2 0 0 411 410 1 1
TLR7 LGALS9 0 0 243 314 1 1
TLR7 AP3B1 0 0 0 201 1 1
TLR7 HSPD1 0 0 254 284 1 1
TLR7 ANXA5 0 0 336 350 1 2
TLR7 CCNB1 0 0 95 185 1 1
TLR7 TNFSF18 0 0 193 193 1 1
TLR7 PLK1 0 0 108 224 1 2
TLR7 TNFSF9 0 0 247 246 1 1
TLR7 CXCL13 0 0 363 376 1 1
TLR7 CLEC4D 0 0 242 308 1 1
TLR7 RANBP2 0 0 0 170 1 1
TLR7 HSPA1L 0 0 61 189 1 1
TLR7 NTN3 0 0 0 167 1 1
TLR7 TECTA 0 0 0 157 1 1
TLR7 ARHGEF6 0 0 0 191 1 1
TLR7 HAVCR1 0 0 72 186 1 1
TLR7 TNFRSF17 0 0 294 319 1 1
TLR7 PLCG2 0 0 252 281 1 1
TLR7 CCL5 0 0 609 647 1 2
TLR7 HCST 0 0 134 195 1 1
TLR7 STAG2 0 0 116 158 1 1
TLR7 IFNG 0 0 464 669 1 2
TLR7 BIRC2 0 0 187 214 1 1
TLR7 LYZ 0 0 108 241 1 1
TLR7 IL6 0 0 759 800 1 2
TLR7 BTLA 0 0 168 273 1 1
TLR7 IL3RA 0 0 620 630 1 1
TLR7 MPO 0 0 367 367 1 2
TLR7 TNFRSF1A 0 0 459 470 1 1
TLR7 LSM4 0 0 0 167 1 1
TLR7 NOTCH1 0 0 208 238 1 2
TLR7 ENTPD1 0 0 226 288 1 1
TLR7 MAST1 0 0 0 180 1 1
TLR7 CD40LG 0 0 606 663 1 1
TLR7 TRAF4 0 0 193 208 1 1
TLR7 CTAG1A 0 0 373 373 1 1
TLR7 HLA-G 0 0 203 220 1 1
TLR7 DDX21 0 0 233 281 1 1
TLR7 MYO1H 0 0 0 155 1 1
TLR7 POTEF 0 0 181 279 1 1
TLR7 KPNA1 0 0 123 156 1 1
TLR7 C4A 0 0 240 292 1 1
TLR7 NLRP1 0 0 420 433 1 1
TLR7 APOBEC3G 0 0 391 417 1 1
TLR7 FCRL4 0 0 202 219 1 1
TLR7 EPHA2 0 0 108 172 1 1
TLR7 FCGR3A 0 0 519 571 1 1
TLR7 SOCS7 0 0 167 180 1 1
TLR7 TNFRSF1B 0 0 255 334 1 1
TLR7 DDX18 0 0 0 164 1 1
TLR7 B7RP1 0 0 402 411 1 1
TLR7 MS4A4A 0 0 81 176 1 1
TLR7 HERC5 0 0 235 247 1 1
TLR7 CXCR2 0 0 339 368 1 1
TLR7 HMGN1 0 0 283 283 1 1
TLR7 MYOM2 0 0 218 218 1 1
TLR7 MFAP1 0 0 0 177 1 1
TLR7 IL1B 0 0 734 787 1 2
TLR7 PRKCB 0 0 123 155 1 2
TLR7 CYP27B1 0 0 155 154 1 1
TLR7 OAS1 0 0 505 533 1 1
TLR7 EDN1 0 0 153 152 1 1
TLR7 HIF1A 0 0 283 294 1 2
TLR7 SIGLEC12 0 0 0 150 1 1
TLR7 TRAF5 0 0 280 309 1 1
TLR7 HCLS1 0 0 0 168 1 1
TLR7 NCR1 0 0 322 321 1 1
TLR7 STAB1 0 0 113 192 1 1
TLR7 NCR3 0 0 229 257 1 1
TLR7 MSRB3 0 0 0 151 1 1
TLR7 GATA3 0 0 294 311 1 1
TLR7 CCL25 0 0 181 181 1 1
TLR7 TRIM23 0 0 153 360 1 1
TLR7 ERN1 0 0 161 202 1 2
TLR7 C1QTNF7 0 0 123 177 1 1
TLR7 STAT3 0 0 508 518 1 2
TLR7 CD55 0 0 162 161 1 1
TLR7 AGO2 0 0 261 274 1 2
TLR7 FCER2 0 0 108 216 1 1
TLR7 SNX22 0 0 45 158 1 1
TLR7 HLA-DQB1 0 0 134 248 1 1
TLR7 SPIC 0 0 89 155 1 1
TLR7 BTN3A2 0 0 0 155 1 1
TLR7 TSC22D3 0 0 160 201 1 1
TLR7 LY86 0 0 294 620 1 1
TLR7 HGS 0 0 123 155 1 2
TLR7 RPGR 0 0 0 157 1 1
TLR7 SNRPD1 0 0 63 174 1 2
TLR7 DAW1 0 0 0 157 1 1
TLR7 FGR 0 0 95 256 1 1
TLR7 SRSF1 0 0 49 156 1 1
TLR7 TRAF1 0 0 244 296 1 1
TLR7 CAMP 0 0 595 606 1 2
TLR7 MOB3B 0 0 0 174 1 1
TLR7 NRXN3 0 0 0 153 1 1
TLR7 RPS16 0 0 0 163 1 1
TLR7 CSF3 0 0 425 435 1 1
TLR7 TXK 0 0 0 155 1 1
TLR7 MUC5B 0 0 123 230 1 1
TLR7 LMNA 0 0 161 161 1 2
TLR7 HLA-DQB2 0 0 0 162 1 1
TLR7 LCP2 0 0 103 553 1 1
TLR7 SPECC1 0 0 112 169 1 1
TLR7 SELPLG 0 0 233 278 1 1
TLR7 LPP 0 0 81 189 1 1
TLR7 KIR3DL2 0 0 142 158 1 1
TLR7 S100A1 0 0 143 179 1 1
TLR7 SCN10A 0 0 108 151 1 1
TLR7 KLRC1 0 0 242 241 1 1
TLR7 IRF9 0 0 518 530 1 1
TLR7 PSTPIP1 0 0 56 301 1 1
TLR7 MYD88 272 900 989 999 1 2
TLR7 FES 0 0 0 225 1 1
TLR7 ADORA3 0 0 294 335 1 1
TLR7 RAB4A 0 0 82 162 1 1
TLR7 SARM1 0 0 469 560 1 1
TLR7 FADD 0 0 323 333 1 2
TLR7 VWCE 0 0 0 165 1 1
TLR7 AKT2 0 0 47 173 1 2
TLR7 ENSG00000272772 0 0 0 209 1 1
TLR7 TLR1 0 0 857 520 1 1
TLR7 NLRP10 0 0 181 181 1 1
TLR7 CAB39 0 0 0 161 1 1
TLR7 DHX58 0 0 612 703 1 1
TLR7 OSM 0 0 128 179 1 1
TLR7 IKZF3 0 0 54 186 1 1
TLR7 MAP2K1 0 0 202 231 1 1
TLR7 CH25H 0 0 122 160 1 1
TLR7 ABCA8 0 0 0 177 1 1
TLR7 NLRP12 0 0 244 266 1 1
TLR7 CD80 0 0 681 830 1 2
TLR7 GRPR 0 0 107 232 1 1
TLR7 FURIN 0 0 207 242 1 1
TLR7 ASGR1 0 0 143 156 1 1
TLR7 SH3BGRL 0 0 0 153 1 1
TLR7 NCKAP1L 0 0 0 193 1 1
TLR7 PPP3CC 0 0 0 182 1 1
TLR7 FXN 0 0 0 167 1 1
TLR7 TAX1BP1 0 0 114 154 1 2
TLR7 NELFCD 0 0 391 390 1 1
TLR7 UBD 0 0 94 150 1 1
TLR7 MPEG1 0 0 0 599 1 1
TLR7 TNFRSF13B 0 0 678 694 1 1
TLR7 CD300A 0 0 215 322 1 1
TLR7 PPP3CB 0 0 0 182 1 1
TLR7 APOH 0 0 124 216 1 1
TLR7 DHX33 0 0 193 283 1 1
TLR7 TAB1 0 0 344 369 1 1
TLR7 LSM5 0 0 0 160 1 1
TLR7 TRAF2 0 0 167 197 1 2
TLR7 MX1 0 0 611 661 1 1
TLR7 CDC40 0 0 0 185 1 1
TLR7 SIGLEC11 0 0 43 151 1 1
TLR7 IL27RA 0 0 171 189 1 1
TLR7 PIK3CA 0 0 47 164 1 2
TLR7 IL18 0 0 662 710 1 2
TLR7 IL1R1 0 0 603 603 1 1
TLR7 CLECL1 0 0 66 174 1 1
TLR7 CWC22 0 0 0 197 1 1
TLR7 ARL8B 0 0 81 161 1 1
TLR7 IFITM3 0 0 325 339 1 1
TLR7 MYC 0 0 289 294 1 2
TLR7 IRGM 0 0 282 297 1 2
TLR7 S100A7 0 0 193 193 1 1
TLR7 TREM1 0 0 322 362 1 1
TLR7 LILRA1 0 0 139 246 1 1
TLR7 PI3 0 0 170 169 1 2
TLR7 SNRPE 0 0 0 154 1 2
TLR7 TAB2 0 0 421 436 1 2
TLR7 SLAMF7 0 0 150 240 1 1
TLR7 CD84 0 0 216 327 1 1
TLR7 TNFAIP2 0 0 118 173 1 1
TLR7 IRF1 0 0 561 594 1 2
TLR7 ATP4A 0 0 122 157 1 1
TLR7 MYBL2 0 0 45 174 1 1
TLR7 TTF1 0 0 0 171 1 1
TLR7 C1QA 0 0 194 536 1 1
TLR7 RPL23 0 0 0 158 1 1
TLR7 CXCR3 0 0 464 508 1 1
TLR7 RPL27A 0 0 0 165 1 1
TLR7 PPT1 0 0 0 156 1 1
TLR7 CALCOCO2 0 0 213 213 1 2
TLR7 ESR1 0 0 218 244 1 2
TLR7 NCL 0 0 144 255 1 2
TLR7 IFNB1 0 0 806 818 1 1
TLR7 POU2AF1 0 0 71 157 1 1
TLR7 PDCD1 0 0 345 381 1 2
TLR7 TRPA1 0 0 922 924 1 1
TLR7 P2RY2 0 0 113 202 1 1
TLR7 EOMES 0 0 150 163 1 1
TLR7 AIRE 0 0 166 180 1 1
TLR7 IL10RB 0 0 335 354 1 1
TLR7 HNRNPDL 0 0 97 193 1 1
TLR7 C3 0 0 325 372 1 2
TLR7 MMP13 0 0 135 170 1 2
TLR7 RAG2 0 0 219 219 1 1
TLR7 CCR9 0 0 370 378 1 1
TLR7 ZMAT1 0 0 0 151 1 1
TLR7 FN1 0 0 358 358 1 2
TLR7 PLK3 0 0 0 165 1 1
TLR7 CD300LB 0 0 108 240 1 1
TLR7 RIPK4 0 0 0 152 1 1
TLR7 ULK1 0 0 307 307 1 2
TLR7 ELANE 0 0 263 274 1 1
TLR7 SLC15A3 0 0 157 226 1 1
TLR7 HAND2 0 0 0 248 1 1
TLR7 MAP1LC3B 0 0 141 175 1 2
TLR7 RIN3 0 0 0 155 1 1
TLR7 SERPINB5 0 0 0 309 1 1
TLR7 XCL1 0 0 208 264 1 1
TLR7 CD1E 0 0 323 341 1 1
TLR7 TBC1D8B 0 0 0 206 1 1
TLR7 OBBP2 297 0 44 367 1 1
TLR7 VAV1 0 0 142 235 1 1
TLR7 TIFAB 0 0 81 180 1 1
TLR7 KCNN4 0 0 144 174 1 1
TLR7 NCF2 0 0 137 317 1 1
TLR7 TXNL4B 0 0 0 171 1 1
TLR7 VAMP3 0 0 150 163 1 1
TLR7 GBP3 0 0 135 169 1 1
TLR7 IRAK4 0 600 689 890 1 1
TLR7 FLT3 0 0 404 461 1 2
TLR7 TBC1D8 0 0 0 197 1 1
TLR7 IL10 0 0 717 762 1 2
TLR7 DMD 0 0 81 230 1 2
TLR7 OTUD5 0 0 209 226 1 1
TLR7 CCL3 0 0 596 645 1 1
TLR7 CTSG 0 0 247 258 1 1
TLR7 FCGR3B 0 0 520 559 1 1
TLR7 CCL22 0 0 358 374 1 1
TLR7 TRIM26 0 0 81 186 1 1
TLR7 CWC25 0 0 0 194 1 1
TLR7 HLA-A 0 0 206 223 1 1
TLR7 LITAF 0 0 86 167 1 1
TLR7 PTPN20A 0 0 48 155 1 1
TLR7 IL18RAP 0 0 164 218 1 1
TLR7 MARCO 0 0 181 390 1 1
TLR7 FCGR2A 0 0 689 725 1 1
TLR7 CD79A 0 0 235 296 1 1
TLR7 DOCK4 0 0 0 182 1 1
TLR7 CLEC4E 0 0 510 547 1 1
TLR7 RORC 0 0 135 154 1 1
TLR7 DOCK8 0 0 163 496 1 1
TLR7 TNFRSF9 0 0 322 329 1 1
TLR7 IL21R 0 0 260 366 1 1
TLR7 FERMT3 0 0 61 191 1 1
TLR7 KIT 0 0 229 268 1 2
TLR7 PDCD1LG2 0 0 371 405 1 1
TLR7 CD200 0 0 269 309 1 1
TLR7 CYTIP 0 0 0 233 1 1
TLR7 PLP2 0 0 145 173 1 1
TLR7 BST2 0 0 560 569 1 1
TLR7 FPR1 0 0 261 321 1 1
TLR7 IFNA21 0 0 535 535 1 1
TLR7 NLRP6 0 0 294 310 1 1
TLR7 CARD16 0 0 0 197 1 1
TLR7 CD53 0 0 97 230 1 1
TLR7 REL 0 0 391 512 1 2
TLR7 NLRP3 0 0 651 701 1 2
TLR7 UBE2V1 0 900 263 924 1 1
TLR7 CASP3 0 0 323 343 1 2
TLR7 F3 0 0 167 199 1 1
TLR7 PTGS2 0 0 330 330 1 2
TLR7 MSR1 0 0 228 280 1 1
TLR7 MRPS16 0 0 0 167 1 1
TLR7 DHX29 0 0 50 179 1 1
TLR7 IL13 0 0 557 557 1 2
TLR7 TNFRSF10B 0 0 232 232 1 2
TLR7 RNASE2 0 0 269 304 1 1
TLR7 TNFSF13B 0 0 610 655 1 1
TLR7 CTSS 0 900 193 961 1 1
TLR7 ACE 0 0 134 267 1 1
TLR7 TRIM22 0 0 234 282 1 1
TLR7 CYBB 0 0 369 559 1 2
TLR7 GPR65 0 0 57 574 1 1
TLR7 FPR3 0 0 167 216 1 1
TLR7 MRC1 0 0 401 500 1 1
TLR7 GUSB 0 0 181 198 1 1
TLR7 CXCL16 0 0 242 260 1 1
TLR7 PPP6C 0 0 56 195 1 1
TLR7 CDKN2A 0 0 181 207 1 2
TLR7 PIGR 0 0 150 178 1 1
TLR7 NRROS 0 0 48 192 1 1
TLR7 IL1RAP 0 0 203 239 1 1
TLR7 PFN1 0 0 0 190 1 1
TLR7 PIK3CD 0 0 84 254 1 1
TLR7 IL13RA1 0 0 151 220 1 1
TLR7 CEBPB 0 0 244 261 1 2
TLR7 ATG16L1 0 0 335 346 1 2
TLR7 ECSIT 0 0 218 218 1 1
TLR7 CIITA 0 0 284 656 1 1
TLR7 MRPL27 0 0 0 180 1 1
TLR7 NOD2 0 0 694 723 1 2
TLR7 RIPK1 0 0 413 454 1 2
TLR7 WWC3 0 0 0 157 1 1
TLR7 LTBR 0 0 261 292 1 1
TLR7 SOCS3 0 0 391 413 1 1
TLR7 IL31 0 0 180 179 1 1
TLR7 IGSF6 0 0 54 620 1 1
TLR7 SLU7 0 0 0 163 1 1
TLR7 MNDA 0 0 106 283 1 1
TLR7 FASLG 0 0 391 404 1 1
TLR7 KDM6B 0 0 94 186 1 1
TLR7 IFNL3 0 0 469 490 1 1
TLR7 RNASE6 0 0 44 223 1 1
TLR7 TNIP1 0 0 324 339 1 1
TLR7 MYO1C 0 0 0 155 1 1
TLR7 CLDN2 0 0 91 150 1 1
TLR7 PTPN18 0 0 0 374 1 1
TLR7 STAT5A 0 0 284 330 1 1
TLR7 RXRA 0 0 92 161 1 1
TLR7 EMR3 0 0 0 157 1 1
TLR7 SNRPB 0 0 74 215 1 1
TLR7 CD3E 0 0 218 276 1 1
TLR7 HLA-B 0 0 167 205 1 1
TLR7 SNRNP200 0 0 0 185 1 1
TLR7 HNRNPC 0 0 108 202 1 1
TLR7 ITGB2 0 0 236 650 1 1
TLR7 LILRB4 0 0 260 350 1 1
TLR7 KRAS 0 0 141 265 1 2
TLR7 IL2 0 0 615 623 1 1
TLR7 TLR6 0 0 806 477 1 1
TLR7 OLR1 0 0 194 206 1 2
TLR7 VSIG4 0 0 57 179 1 1
TLR7 ANXA1 0 0 134 155 1 1
TLR7 ITGA2 0 0 165 202 1 1
TLR7 LRP1 0 0 217 251 1 1
TLR7 VAMP5 0 0 53 227 1 1
TLR7 BECN1 0 0 325 377 1 2
TLR7 MYO16 0 0 0 161 1 1
TLR7 HLA-DPA1 0 0 72 156 1 1
TLR7 ZC3HAV1 0 0 184 201 1 1
TLR7 ENSG00000262660 0 0 0 156 1 1
TLR7 CAB39L 0 0 0 161 1 1
TLR7 HSH2D 0 0 125 157 1 1
TLR7 SSB 0 0 247 262 1 1
TLR7 DUSP1 0 0 252 305 1 1
TLR7 ISY1-RAB43 0 0 0 189 1 1
TLR7 CCDC130 0 0 0 180 1 1
TLR7 RBM22 0 0 0 213 1 1
TLR7 IFNA13 0 0 261 261 1 1
TLR7 UNC93A 0 0 62 161 1 1
TLR7 IL18R1 0 0 205 205 1 1
TLR7 IFNA17 0 0 535 535 1 1
TLR7 CARD11 0 0 162 609 1 1
TLR7 HLA-DRA 0 0 127 231 1 1
TLR7 CD81 0 0 304 321 1 1
TLR7 CD72 0 0 468 546 1 1
TLR7 CLEC4C 0 0 681 685 1 1
TLR7 CFH 0 0 170 246 1 1
TLR7 IFNLR1 0 0 339 339 1 1
TLR7 XIAP 0 0 175 266 1 2
TLR7 SERPINB6 0 0 0 254 1 1
TLR7 LPHN3 0 0 0 176 1 1
TLR7 HAS3 0 0 73 201 1 1
TLR7 ALOX5AP 0 0 73 243 1 1
TLR7 IKBKB 0 0 505 533 1 2
TLR7 SWAP70 0 0 101 162 1 1
TLR7 SLC10A1 0 0 139 305 1 1
TLR7 KLF4 0 0 143 179 1 2
TLR7 PANX1 0 0 180 179 1 1
TLR7 CARD8 0 0 91 150 1 1
TLR7 CARD14 0 0 182 240 1 1
TLR7 CD4 0 0 763 818 1 2
TLR7 MRPL33 0 0 0 167 1 1
TLR7 GBP2 0 0 217 269 1 1
TLR7 AKT1 0 0 418 495 1 2
TLR7 CYTH4 0 0 0 539 1 1
TLR7 TGFB2 0 0 161 174 1 1
TLR7 PPARG 0 0 258 283 1 2
TLR7 IL12RB1 0 0 294 331 1 1
TLR7 LY96 0 0 651 683 1 1
TLR7 IL17C 0 0 164 163 1 1
TLR7 CD48 0 0 129 252 1 1
TLR7 ARG2 0 0 261 261 1 1
TLR7 ERBB2 0 0 246 294 1 2
TLR7 CR2 0 0 455 463 1 1
TLR7 IRF3 0 0 760 760 1 2
TLR7 NLRP7 0 0 160 212 1 1
TLR7 CCL3L3 0 0 154 245 1 1
TLR7 CFP 0 0 157 288 1 1
TLR7 CD1D 0 0 466 482 1 1
TLR7 PYCARD 0 0 359 373 1 2
TLR7 MAP3K1 0 0 134 258 1 1
TLR7 YME1L1 0 0 0 167 1 1
TLR7 IL6ST 0 0 181 181 1 1
TLR7 TLR9 0 800 915 838 1 2
TLR7 NTN5 0 0 0 167 1 1
TLR7 CLEC12B 0 0 123 168 1 1
TLR7 MALT1 0 0 226 242 1 1
TLR7 CXCL10 0 0 681 699 1 2
TLR7 USH2A 0 0 54 180 1 1
TLR7 ZBTB46 0 0 231 246 1 1
TLR7 ID2 0 0 193 193 1 1
TLR7 PRPF39 0 0 0 190 1 1
TLR7 SIGLEC6 0 0 164 256 1 1
TLR7 TCERG1L 0 0 0 161 1 1
TLR7 LSM7 0 0 0 169 1 1
TLR7 DHX35 0 0 0 209 1 1
TLR7 IL24 0 0 134 155 1 2
TLR7 EIF2AK3 0 0 210 238 1 2
TLR7 STK25 0 0 0 182 1 1
TLR7 STAT6 0 0 335 375 1 1
TLR7 HFM1 0 0 0 185 1 1
TLR7 SUOX 0 0 0 261 1 1
TLR7 ROBO2 0 0 0 189 1 1
TLR7 PLSCR1 0 0 189 207 1 1
TLR7 LGALS3 0 0 212 308 1 2
TLR7 FRMPD2 0 0 0 157 1 1
TLR7 CADM1 0 0 204 218 1 1
TLR7 ADAM22 0 0 217 234 1 1
TLR7 TNFRSF18 0 0 249 248 1 1
TLR7 FLT1 0 0 136 180 1 1
TLR7 SRC 0 0 310 344 1 2
TLR7 GPR112 0 0 0 228 1 1
TLR7 SAMD9L 0 0 57 181 1 1
TLR7 HP 0 0 134 173 1 1
TLR7 GRAP 0 0 0 150 1 1
TLR7 DOCK2 0 0 246 455 1 1
TLR7 BPI 0 0 134 154 1 1
TLR7 EEA1 0 0 244 258 1 2
TLR7 CD47 0 0 270 282 1 2
TLR7 GFM1 0 0 0 181 1 1
TLR7 YWHAB 0 0 0 161 1 1
TLR7 IL26 0 0 172 171 1 1
TLR7 KDM6A 0 0 0 228 1 1
TLR7 IL36B 0 0 134 225 1 1
TLR7 IFIT1 0 0 561 599 1 1
TLR7 CDA 0 0 137 156 1 1
TLR7 CCR4 0 0 66 193 1 1
TLR7 GPATCH8 0 0 0 190 1 1
TLR7 CD2 0 0 267 310 1 1
TLR7 C1QB 0 0 281 639 1 1
TLR7 ADORA2B 0 0 283 282 1 1
TLR7 PF4 0 0 220 237 1 1
TLR7 ENSG00000244255 0 0 113 152 1 1
TLR7 ARHGAP15 0 0 0 152 1 1
TLR7 SF3B1 0 0 0 238 1 1
TLR7 PTPN7 0 0 0 200 1 1
TLR7 NFATC2 0 0 139 160 1 1
TLR7 LILRA5 0 0 125 186 1 1
TLR7 LYST 0 0 58 271 1 1
TLR7 NWD1 0 0 0 177 1 1
TLR7 ICOS 0 0 210 285 1 1
TLR7 EIF2S1 0 0 235 235 1 2
TLR7 PTPRQ 0 0 0 174 1 1
TLR7 ANPEP 0 0 156 174 1 1
TLR7 NTN1 0 0 0 167 1 1
TLR7 JAK1 0 0 406 436 1 2
TLR7 HMOX1 0 0 210 210 1 2
TLR7 TRIM14 0 0 150 238 1 1
TLR7 TICAM2 0 0 391 531 1 1
TLR7 NCR2 0 0 294 309 1 1
TLR7 PPBP 0 0 134 305 1 1
TLR7 RHOH 0 0 55 205 1 1
TLR7 CAT 0 0 180 203 1 2
TLR7 CCL1 0 0 152 172 1 1
TLR7 CANX 0 0 159 172 1 2
TLR7 CWF19L2 0 0 0 174 1 1
TLR7 TRAF3IP2 0 0 160 159 1 1
TLR7 HGF 0 0 167 197 1 2
TLR7 SFTPD 0 0 162 231 1 1
TLR7 SRRM3 0 0 0 197 1 1
TLR7 IFI44 0 0 325 347 1 1
TLR7 ARHGAP6 0 0 74 165 1 1
TLR7 RNASEL 0 0 509 581 1 1
TLR7 RBM25 0 0 0 387 1 1
TLR7 HPRT1 0 0 293 296 1 1
TLR7 MLANA 0 0 248 248 1 1
TLR7 PTPN2 0 0 81 185 1 2
TLR7 MYB 0 0 85 209 1 1
TLR7 CCL19 0 0 414 439 1 1
TLR7 CTLA4 0 0 600 608 1 2
TLR7 MLC1 0 0 66 271 1 1
TLR7 CD97 0 0 54 168 1 1
TLR7 CSF2RB 0 0 112 597 1 1
TLR7 CD274 0 0 561 597 1 2
TLR7 HLA-E 0 0 201 245 1 1
TLR7 FLT3LG 0 0 505 523 1 1
TLR7 HEXB 0 0 46 151 1 1
TLR7 PPT2 0 0 0 156 1 1
TLR7 HK3 0 0 0 166 1 1
TLR7 PRPF19 0 0 0 234 1 1
TLR7 NTRK1 0 0 117 179 1 1
TLR7 HMSD 0 0 0 206 1 1
TLR7 KLRG1 0 0 161 174 1 1
TLR7 P2RY10 0 0 0 297 1 1
TLR7 DDX60 0 0 261 289 1 1
TLR7 LOX 0 0 147 171 1 2
TLR7 GNLY 0 0 180 210 1 1
TLR7 USHBP1 0 0 0 167 1 1
TLR7 RPS6KB1 0 0 135 192 1 2
TLR7 FCGR1A 0 0 418 488 1 1
TLR7 REM1 0 0 0 157 1 1
TLR7 MUC1 0 0 248 248 1 1
TLR7 NLRP2 0 0 119 174 1 1
TLR7 AHR 0 0 220 220 1 2
TLR7 SERPINE1 0 0 123 162 1 1
TLR7 LRRC25 0 0 0 158 1 1
TLR7 IRF7 0 600 844 944 1 1
TLR7 ITIH4 0 0 460 472 1 1
TLR7 SOCS4 0 0 176 188 1 1
TLR7 DDX53 0 0 284 329 1 1
TLR7 UVRAG 0 0 156 155 1 2
TLR7 SYF2 0 0 0 210 1 1
TLR7 MERTK 0 0 234 288 1 1
TLR7 EVI2A 0 0 0 179 1 1
TLR7 MS4A14 0 0 0 161 1 1
TLR7 IFNL1 0 0 505 524 1 1
TLR7 IFI35 0 0 203 218 1 1
TLR7 CASK 0 0 0 257 1 1
TLR7 LSM8 0 0 0 167 1 1
TLR7 ATF3 0 0 186 216 1 2
TLR7 CD9 0 0 214 214 1 1
TLR7 RAB7A 0 0 218 242 1 2
TLR7 S100A9 0 0 134 215 1 1
TLR7 DRAM1 0 0 117 164 1 2
TLR7 IFI16 0 0 518 536 1 1
TLR7 MMP8 0 0 147 176 1 1
TLR7 IFNL2 0 0 455 476 1 1
TLR7 IL5 0 0 518 518 1 1
TLR7 CD70 0 0 423 427 1 1
TLR7 MAP3K14 0 0 95 225 1 1
TLR7 IL1R2 0 0 218 239 1 1
TLR7 TFRC 0 0 251 263 1 1
TLR7 NFKB2 0 0 294 331 1 1
TLR7 IL34 0 0 173 203 1 1
TLR7 SPN 0 0 310 391 1 1
TLR7 ATP12A 0 0 122 157 1 1
TLR7 TNFAIP3 0 0 421 447 1 2
TLR7 EMB 0 0 362 362 1 1
TLR7 RNF135 0 0 284 296 1 1
TLR7 NFAT5 0 0 69 162 1 1
TLR7 RBM8A 0 0 171 171 1 1
TLR7 EEF2 0 0 0 181 1 2
TLR7 IFI27 0 0 281 296 1 1
TLR7 MS4A6A 0 0 45 192 1 1
TLR7 NAIP 0 0 254 324 1 1
TLR7 PRPF6 0 0 0 169 1 1
TLR7 CLEC10A 0 0 218 296 1 1
TLR7 ITK 0 0 100 232 1 1
TLR7 DCT 0 0 203 203 1 1
TLR7 NT5E 0 0 195 208 1 1
TLR7 VDR 0 0 162 190 1 2
TLR7 IL1RN 0 0 310 344 1 1
TLR7 CGI-74 0 0 0 183 1 1
TLR7 MMP3 0 0 159 172 1 1
TLR7 TNF 0 0 758 809 1 2
TLR7 NBR1 0 0 150 172 1 2
TLR7 IFITM1 0 0 334 348 1 1
TLR7 BCAS2 0 0 0 179 1 1
TLR7 MRPL15 0 0 0 165 1 1
TLR7 MRPL20 0 0 0 167 1 1
TLR7 PTPRK 0 0 44 152 1 1
TLR7 DICER1 0 0 301 390 1 1
TLR7 PDZD2 0 0 0 193 1 1
TLR7 HSPA4 0 0 633 659 1 1
TLR7 IRF2 0 0 341 355 1 1
TLR7 CXCL9 0 0 504 528 1 1
TLR7 IL12B 0 0 82 214 1 1
TLR7 TEK 0 0 113 158 1 1
TLR7 PPARA 0 0 142 171 1 2
TLR7 DDX1 0 0 233 281 1 1
TLR7 CCR2 0 0 501 611 1 2
TLR7 ISG20 0 0 369 389 1 1
TLR7 PDCD4 0 0 161 174 1 2
TLR7 CLEC12A 0 0 212 294 1 1
TLR7 XPO5 0 0 193 224 1 1
TLR7 HSP90B1 0 600 369 740 1 1
TLR7 RAC3 0 0 45 222 1 2
TLR7 DHX36 0 0 369 490 1 1
TLR7 CXCL11 0 0 405 405 1 1
TLR7 DUSP12 0 0 97 179 1 1
TLR7 CYCS 0 0 193 210 1 2
TLR7 TRAF6 0 900 683 970 1 2
TLR7 PYHIN1 0 0 143 207 1 1
TLR7 VCAN 0 0 134 160 1 1
TLR7 FCGRT 0 0 194 211 1 1
TLR7 MRPL3 0 0 0 165 1 1
TLR7 RASAL3 0 0 0 154 1 1
TLR7 PELI1 0 0 148 232 1 1
TLR7 DOCK11 0 0 0 237 1 1
TLR7 PRTN3 0 0 264 275 1 1
TLR7 EGF 0 0 253 264 1 2
TLR7 CRNKL1 0 0 0 213 1 1
TLR7 MAPK8 0 0 294 335 1 2
TLR7 KLRD1 0 0 260 304 1 1
TLR7 LILRB2 0 0 211 339 1 1
TLR7 NTNG1 0 0 0 213 1 1
TLR7 SNRNP70 0 0 193 283 1 1
TLR7 DIABLO 0 0 151 182 1 2
TLR7 SF3B4 0 0 0 181 1 1
TLR7 IL1F10 0 0 161 213 1 1
TLR7 CEACAM8 0 0 182 181 1 1
TLR7 VR1 0 0 248 266 1 1
TLR7 BATF3 0 0 390 407 1 1
TLR7 CCR1 0 0 391 519 1 1
TLR7 PPP2CB 0 0 0 182 1 1
TLR7 P2RX7 0 0 314 441 1 2
TLR7 NMBR 0 0 388 388 1 1
TLR7 MAF 0 0 174 192 1 1
TLR7 FAM26F 0 0 48 163 1 1
TLR7 PPP1CB 0 0 46 186 1 1
TLR7 SIGLEC9 297 0 70 434 1 1
TLR7 TRADD 0 0 291 336 1 1
TLR7 PIK3AP1 0 0 117 211 1 1
TLR7 GBP1 0 0 252 299 1 1
TLR7 LONRF3 0 0 0 185 1 1
TLR7 KLHL6 0 0 0 536 1 1
TLR7 CRYGC 0 0 292 292 1 1
TLR7 DDX41 0 0 424 446 1 1
TLR7 SGK494 0 0 0 174 1 1
TLR7 AGER 0 0 369 369 1 2
TLR7 ABCA9 0 0 0 177 1 1
TLR7 NCF4 0 0 123 229 1 1
TLR7 CDH1 0 0 181 193 1 2
TLR7 WAC 0 0 0 161 1 1
TLR7 MB21D1 0 0 610 620 1 1
TLR7 DUSP10 0 0 57 150 1 1
TLR7 CD33 0 0 294 498 1 1
TLR7 IL27 0 0 204 239 1 1
TLR7 MSRB2 0 0 0 151 1 1
TLR7 PLD3 0 0 47 271 1 1
TLR7 SCARB1 0 0 217 235 1 1
TLR7 IL4 0 0 654 657 1 1
TLR7 PDGFRB 0 0 118 163 1 2
TLR7 SIRPA 0 0 391 405 1 1
TLR7 EP300 0 0 170 200 1 2
TLR7 SMAD3 0 0 149 164 1 2
TLR7 IL17F 0 0 370 370 1 1
TLR7 PLS3 0 0 0 169 1 1
TLR7 BIRC3 0 0 187 256 1 1
TLR7 IFNA6 0 0 264 264 1 1
TLR7 CCL2 0 0 611 631 1 2
TLR7 GYPC 0 0 184 183 1 1
TLR7 ALB 0 0 414 475 1 2
TLR7 CD68 0 0 391 426 1 2
TLR7 ENPEP 0 0 140 193 1 1
TLR7 IDO1 0 0 451 451 1 1
TLR7 IL16 0 0 184 360 1 1
TLR7 IFI6 0 0 203 203 1 1
TLR7 CARD17 0 0 0 156 1 1
TLR7 MME 0 0 140 158 1 1
TLR7 CASP7 0 0 125 151 1 1
TLR7 TYROBP 0 0 382 493 1 1
TLR7 NAA38 0 0 0 154 1 1
TLR7 LTB 0 0 150 183 1 1
TLR7 LSM2 0 0 0 154 1 1
TLR7 LBP 0 0 180 199 1 1
TLR7 IFNA16 0 0 194 194 1 1
TLR7 HSP90AA1 0 0 541 548 1 2
TLR7 MBL2 0 0 286 297 1 1
TLR7 IL21 0 0 164 216 1 1
TLR7 DHX57 0 0 0 178 1 1
TLR7 SPIN3 0 0 0 183 1 1
TLR7 IFIT5 0 0 260 372 1 1
TLR7 CLEC2D 0 0 134 196 1 1
TLR7 ATF2 0 0 134 188 1 1
TLR7 CRP 0 0 324 325 1 2
TLR7 SELP 0 0 260 339 1 1
TLR7 EMR2 0 0 45 160 1 1
TLR7 EPRS 0 0 187 266 1 1
TLR7 SELL 0 0 454 512 1 1
TLR7 RPS2 0 0 0 185 1 1
TLR7 GPR34 0 0 82 207 1 1
TLR7 C1S 0 0 165 207 1 1
TLR7 NLRX1 0 0 368 383 1 2
TLR7 STK38 0 0 0 167 1 1
TLR7 MMP9 0 0 321 351 1 2
TLR7 MAPK3 0 0 320 336 1 2
TLR7 THY1 0 0 204 210 1 1
TLR7 HLA-DMB 0 0 91 182 1 1
TLR7 MICB 0 0 151 150 1 1
TLR7 SQSTM1 0 0 202 221 1 2
TLR7 MFNG 0 0 0 186 1 1
TLR7 CSF2RA 0 0 202 355 1 1
TLR7 SPP1 0 0 415 428 1 2
TLR7 IFNA7 0 0 167 167 1 1
TLR7 CD1C 0 0 602 643 1 1
TLR7 BANK1 0 0 442 479 1 1
TLR7 FGL2 0 0 45 346 1 1
TLR7 IFNAR2 0 0 508 508 1 1
TLR7 CRLF2 0 0 134 174 1 1
TLR7 AURKA 0 0 47 160 1 2
TLR7 GPR29 0 0 387 401 1 1
TLR7 TIMP1 0 0 170 183 1 1
TLR7 CCL18 0 0 195 305 1 1
TLR7 BCL10 0 0 294 369 1 1
TLR7 LILRA6 0 0 113 175 1 1
TLR7 SF3B2 0 0 0 236 1 1
TLR7 PTPRC 0 0 589 832 1 1
TLR7 CXCR1 0 0 261 282 1 1
TLR7 RHBDF2 0 0 113 154 1 1
TLR7 CRTAM 0 0 48 195 1 1
TLR7 IGDCC3 0 0 0 195 1 1
TLR7 PTPRO 0 0 0 175 1 1
TLR7 ICAM1 0 0 470 494 1 2
TLR7 ROBO1 0 0 0 189 1 1
TLR7 LY9 0 0 134 585 1 1
TLR7 CLEC6A 0 0 421 464 1 1
TLR7 PQBP1 0 0 90 282 1 1
TLR7 JAG1 0 0 134 182 1 1
TLR7 TXNL4A 0 0 0 171 1 1
TLR7 IFNK 0 0 212 333 1 1
TLR7 FYN 0 0 166 207 1 1
TLR7 NFKBIE 0 0 143 203 1 1
TLR7 PARP14 0 0 77 199 1 1
TLR7 LTA 0 0 289 427 1 1
TLR7 IL7R 0 0 343 443 1 1
TLR7 RPL3 0 0 0 165 1 1
TLR7 IL36RN 0 0 213 241 1 1
TLR7 EIF2AK2 0 0 390 437 1 2
TLR7 MOB2 0 0 0 154 1 1
TLR7 FER 0 0 48 201 1 1
TLR7 RAP2C 0 0 0 162 1 1
TLR7 CNPY3 0 600 422 765 1 1
TLR7 TREM2 0 0 265 377 1 1
TLR7 TNFRSF13C 0 0 405 432 1 1
TLR7 IRF6 0 0 108 169 1 1
TLR7 SIGLEC14 0 0 98 243 1 1
TLR7 ALG13 0 0 0 151 1 1
TLR7 CCNA2 0 0 68 161 1 1
TLR7 PVR 0 0 141 174 1 1
TLR7 TRIM38 0 0 203 244 1 1
TLR7 PIK3CG 0 0 161 317 1 1
TLR7 PADI4 0 0 218 240 1 1
TLR7 TFIP11 0 0 0 190 1 1
TLR7 JAK3 0 0 181 250 1 1
TLR7 SH2D3C 0 0 208 241 1 1
TLR7 AIF1 0 0 263 352 1 2
TLR7 CXorf58 0 0 0 167 1 1
TLR7 ENSG00000173366 0 0 919 207 1 1
TLR7 PTCRA 0 0 90 167 1 1
TLR7 GZMA 0 0 193 252 1 1
TLR7 SLC9A7 0 0 0 173 1 1
TLR7 SERPINB2 0 0 67 342 1 1
TLR7 ITGAL 0 0 257 361 1 1
TLR7 TYK2 0 0 455 493 1 1
TLR7 DHX15 0 0 57 162 1 1
TLR7 TAPBP 0 0 195 212 1 1
TLR7 JUN 0 0 497 501 1 2
TLR7 GAPDH 0 0 517 552 1 2
TLR7 LPAR5 0 0 0 520 1 1
TLR7 DUSP5 0 0 123 185 1 1
TLR7 PML 0 0 134 181 1 2
TLR7 B3GAT1 0 0 167 167 1 1
TLR7 CD22 0 0 321 471 1 1
TLR7 BUD31 0 0 0 226 1 1
TLR7 FAM214B 0 0 261 269 1 1
TLR7 CX3CL1 0 0 324 338 1 1
TLR7 CD1A 0 0 322 346 1 1
TLR7 MAP2K7 0 0 235 283 1 1
TLR7 CD83 0 0 594 603 1 1
TLR7 OAS2 0 0 391 502 1 1
TLR7 TNFSF15 0 0 204 204 1 1
TLR7 TLR10 0 0 739 481 1 1
TLR7 ZAP70 0 0 234 342 1 1
TLR7 STAT4 0 0 391 464 1 1
TLR7 ITGA4 0 0 243 291 1 1
TLR7 SF3A1 0 0 0 196 1 1
TLR7 SNRPD3 0 0 44 157 1 1
TLR7 P2RY8 0 0 0 529 1 1
TLR7 TRIM25 0 0 390 453 1 1
TLR7 RELA 0 0 391 403 1 2
TLR7 NFKB1 0 0 337 383 1 2
TLR7 PLK4 0 0 0 165 1 1
TLR7 RBMX2 0 0 0 197 1 1
TLR7 PRPF4 0 0 0 157 1 1
TLR7 NKTR 0 0 118 203 1 1
TLR7 INPPL1 0 0 46 519 1 1
TLR7 TNFSF13 0 0 157 264 1 1
TLR7 IL1RAPL1 0 0 171 251 1 1
TLR7 ZFX 0 0 0 152 1 1
TLR7 HDX 0 0 0 154 1 1
TLR7 C5AR1 0 0 285 545 1 1
TLR7 IL4R 0 0 260 276 1 1
TLR7 HLA-DPB1 0 0 103 156 1 1
TLR7 CREBBP 0 0 135 198 1 1
TLR7 DGCR8 0 0 165 165 1 1
TLR7 ARHGAP30 0 0 45 187 1 1
TLR7 BCL11B 0 0 75 172 1 1
TLR7 FRAS1 0 0 0 154 1 1
TLR7 IGJ 0 0 168 269 1 1
TLR7 CREB1 0 0 254 254 1 2
TLR7 GSDMD 0 0 181 228 1 2
TLR7 NOX3 0 0 0 181 1 1
TLR7 IL2RB 0 0 205 390 1 1
TLR7 DHX9 0 0 261 409 1 1
TLR7 HLA-DQA2 0 0 170 212 1 1
TLR7 CTRL 0 0 143 156 1 2
TLR7 CXCL14 0 0 143 196 1 1
TLR7 MOG 0 0 253 252 1 1
TLR7 SNRPA 0 0 126 299 1 1
TLR7 MAP3K2 0 0 0 179 1 1
TLR7 PPP4C 0 0 0 182 1 1
TLR7 NLRC3 0 0 260 317 1 1
TLR7 BRWD3 0 0 0 170 1 1
TLR7 PIK3C3 0 0 217 229 1 2
TLR7 GZMB 0 0 459 483 1 1
TLR7 PLEK 0 0 108 616 1 1
TLR7 OCLN 0 0 184 183 1 1
TLR7 SRRM2 0 0 0 197 1 1
TLR7 STAT1 0 0 631 662 1 2
TLR7 SOCS5 0 0 218 230 1 1
TLR7 DEFB1 0 0 240 239 1 1
TLR7 LSM3 0 0 0 182 1 1
TLR7 PABPC5 0 0 0 179 1 1
TLR7 CXCR4 0 0 617 636 1 2
TLR7 CD163 0 0 438 482 1 1
TLR7 ADAR 0 0 323 347 1 1
TLR7 MTOR 0 0 297 307 1 2
TLR7 APP 0 0 195 224 1 2
TLR7 IFNA4 0 0 358 358 1 1
TLR7 EGR1 0 0 165 181 1 2
TLR7 TRPV1 0 0 248 266 1 2
TLR7 MRPL12 0 0 0 156 1 1
TLR7 PPP1R42 0 0 0 163 1 1
TLR7 CTNNB1 0 0 211 227 1 2
TLR7 HRAS 0 0 180 251 1 2
TLR7 EFTUD1 0 0 0 181 1 1
TLR7 IKBKE 0 0 455 586 1 1
TLR7 WDR25 0 0 0 185 1 1
TLR7 APOBEC3B 0 0 112 210 1 1
TLR7 PASK 0 0 0 152 1 1
TLR7 C3AR1 0 0 269 539 1 1
TLR7 RAB5A 0 0 150 203 1 2
TLR7 CNPY4 0 0 257 272 1 1
TLR7 FOLR2 0 0 71 165 1 1
TLR7 CTSL 0 900 202 916 1 2
TLR7 ZMAT5 0 0 0 177 1 1
TLR7 NFKBID 0 0 157 202 1 1
TLR7 IL6R 0 0 283 312 1 1
TLR7 PLD4 0 0 66 505 1 1
TLR7 CXCL8 0 0 681 726 1 2
TLR7 ENSG00000268500 0 0 44 224 1 1
TLR7 MCOLN1 0 0 146 182 1 2
TLR7 MUC5AC 0 0 166 268 1 1
TLR7 MICA 0 0 201 201 1 1
TLR7 PPP1R11 0 0 0 227 1 1
TLR7 IFNA2 0 0 517 535 1 1
TLR7 HBEGF 0 0 251 250 1 1
TLR7 CD300C 0 0 150 244 1 1
TLR7 EIF2AK4 0 0 193 193 1 2
TLR7 PTPN22 0 0 342 713 1 1
TLR7 APAF1 0 0 134 156 1 2
TLR7 BUD13 0 0 0 183 1 1
TLR7 NLRC5 0 0 243 383 1 1
TLR7 JAK2 0 0 294 329 1 2
TLR7 NR4A1 0 0 193 208 1 2
TLR7 MYBL1 0 0 0 171 1 1
TLR7 CARD9 0 0 395 410 1 1
TLR7 DOK3 0 0 113 172 1 1
TLR7 PSTPIP2 0 0 48 206 1 1
TLR7 IRAK1 0 900 753 977 1 1
TLR7 DCAF12L1 0 0 0 173 1 1
TLR7 CXorf22 0 0 0 156 1 1
TLR7 EDA 0 0 54 170 1 1
TLR7 ZBP1 0 0 338 393 1 1
TLR7 NFKBIZ 0 0 243 283 1 1
TLR7 CD200R1 0 0 294 339 1 1
TLR7 MAP3K7 0 0 369 400 1 2
TLR7 NLRP4 0 0 211 212 1 1
TLR7 TDRP 0 0 0 189 1 1
TLR7 CWC15 0 0 0 219 1 1
TLR7 MSL3 0 0 74 188 1 1
TLR7 LCN2 0 0 208 225 1 1
TLR7 TP53 0 0 324 323 1 2
TLR7 EGFR 0 0 450 485 1 2
TLR7 CFLAR 0 0 217 277 1 2
TLR7 EFHC2 0 0 0 256 1 1
TLR7 PPP1CC 0 0 59 197 1 1
TLR7 DEFB103A 0 0 302 302 1 1
TLR7 CD2BP2 0 0 206 218 1 1
TLR7 TNFRSF4 0 0 391 408 1 1
TLR7 LAMP1 0 0 390 390 1 2
TLR7 TSLP 0 0 404 404 1 1
TLR7 BTN3A1 0 0 70 176 1 1
TLR7 CDC5L 0 0 0 171 1 1
TLR7 LILRB1 0 0 283 380 1 1
TLR7 VGLL3 0 0 75 231 1 1
TLR7 CLEC1B 0 0 150 193 1 1
TLR7 TCF3 0 0 180 193 1 1
TLR7 FUT4 0 0 180 179 1 1
TLR7 MAP3K8 0 0 208 340 1 1
TLR7 IFITM2 0 0 233 249 1 1
TLR7 CCL21 0 0 391 404 1 1
TLR7 OASL 0 0 336 407 1 1
TLR7 TFEC 0 0 0 193 1 1
TLR7 MDC1 0 0 156 155 1 1
TLR7 CLEC4A 0 0 469 521 1 1
TLR7 MOSPD2 0 0 0 167 1 1
TLR7 PRSS57 0 0 171 183 1 1
TLR7 OAS3 0 0 340 437 1 1
TLR7 GOLPH3 0 0 170 169 1 1
TLR7 LY75 0 0 520 580 1 1
TLR7 LAG3 0 0 341 341 1 1
TLR7 SUCNR1 0 0 156 181 1 1
TLR7 ACTA1 0 0 74 152 1 1
TLR7 IL1RL2 0 0 288 298 1 1
TLR7 FAM78A 0 0 0 154 1 1
TLR7 IL12A 0 0 0 248 1 1
TLR7 CASP10 0 0 144 214 1 1
TLR7 ADORA1 0 0 283 282 1 1
TLR7 EFTUD2 0 0 0 181 1 1
TLR7 MEFV 0 0 459 505 1 1
TLR7 TMEM154 0 0 113 175 1 1
TLR7 SLC15A4 0 0 423 439 1 1
TLR7 IL2RA 0 0 288 343 1 1
TLR7 SF3A2 0 0 0 192 1 1
TLR7 DHX40 0 0 61 166 1 1
TLR7 ROR1 0 0 115 178 1 1
TLR7 CEACAM5 0 0 171 171 1 1
TLR7 TOP1 0 0 113 165 1 1
TLR7 SLC2A6 0 0 0 197 1 1
TLR7 LGMN 0 900 181 916 1 1
TLR7 IFNA1 0 0 865 865 1 1
TLR7 FCGR1B 0 0 0 157 1 1
TLR7 PPP5C 0 0 0 182 1 1
TLR7 ITGAE 0 0 510 525 1 1
TLR7 RNF125 0 0 216 225 1 1
TLR7 IL15 0 0 519 577 1 1
TLR7 TAGAP 0 0 66 255 1 1
TLR7 IL36G 0 0 118 209 1 1
TLR7 TCERG1 0 0 0 161 1 1
TLR7 ROBO4 0 0 0 163 1 1
TLR7 PRB1 0 0 203 203 1 1
TLR7 HLA-C 0 0 164 182 1 1
TLR7 PTPN1 0 0 89 192 1 1
TLR7 SASH3 0 0 0 227 1 1
TLR7 MOB3C 0 0 0 192 1 1
TLR7 XBP1 0 0 266 266 1 2
TLR7 FAM46D 0 0 0 158 1 1
TLR7 SCARF1 0 0 150 175 1 1
TLR7 FAM120B 0 0 156 155 1 1
TLR7 GYPA 0 0 156 155 1 1
TLR7 STAT2 0 0 518 559 1 1
TLR7 SH2D3A 0 0 323 323 1 1
TLR7 ITGB3 0 0 96 217 1 1
TLR7 TIA1 0 0 73 177 1 1
TLR7 TLR8 270 800 913 897 1 1
TLR7 MAGEA1 0 0 180 179 1 1
TLR7 PPP5D1 0 0 0 182 1 1
TLR7 LAPTM5 0 0 72 205 1 1
TLR7 ATG5 0 0 392 395 1 2
TLR7 MAP2K6 0 0 140 172 1 1
TLR7 RAC1 0 0 73 213 1 2
TLR7 HMGB1 0 0 633 633 1 2
TLR7 DUOX2 0 0 103 176 1 1
TLR7 IRF5 0 0 738 772 1 1
TLR7 PPP1CA 0 0 142 280 1 1
TLR7 CTSK 0 900 155 914 1 2
TLR7 LYN 0 0 396 467 1 1
TLR7 RCVRN 0 0 0 195 1 1
TLR7 RGS1 0 0 90 253 1 1
TLR7 GATA2 0 0 112 224 1 1
TLR7 ITGAM 0 0 634 717 1 1
TLR7 MAP3K5 0 0 141 216 1 1
TLR7 ACKR2 0 0 393 392 1 1
TLR7 ERVW-1 0 0 367 367 1 1
TLR7 MCL1 0 0 167 214 1 2
TLR7 ELF4 0 0 129 186 1 1
TLR7 CR1 0 0 180 256 1 1
TLR7 CST7 0 0 45 178 1 1
TLR7 NOX1 0 0 95 258 1 1
TLR7 SPI1 0 0 337 670 1 1
TLR7 CTSB 0 900 278 926 1 2
TLR7 AKT3 0 0 0 167 1 2
TLR7 IL5RA 0 0 150 236 1 1
TLR7 UPRT 0 0 81 158 1 1
TLR7 CXCR5 0 0 392 466 1 1
TLR7 MAP4K4 0 0 120 193 1 1
TLR7 CCR7 0 0 556 581 1 1
TLR7 IKBKG 0 0 491 518 1 1
TLR7 C1QC 0 0 181 519 1 1
TLR7 TIAL1 0 0 60 165 1 1
TLR7 NCAM1 0 0 418 428 1 1
TLR7 TBX21 0 0 460 499 1 1
TLR7 LILRB3 0 0 207 263 1 1
TLR7 PACSIN2 0 0 0 151 1 1
TLR7 ADAM17 0 0 171 184 1 1
TLR7 SUGT1 0 0 0 175 1 1
TLR7 SERPINB9 0 0 57 191 1 1
TLR7 SERPINB8 0 0 0 309 1 1
TLR7 NFKBIB 0 0 203 264 1 1
TLR7 MYO1F 0 0 0 283 1 1
TLR7 LY6E 0 0 203 220 1 1
TLR7 WDFY4 0 0 60 561 1 1
TLR7 ISG15 0 0 564 615 1 2
TLR7 CXorf36 0 0 0 156 1 1
TLR7 CMA1 0 0 181 193 1 1
TLR7 ENSG00000255819 0 0 370 406 1 1
TLR7 SOCS6 0 0 184 196 1 1
TLR7 TGFBR1 0 0 108 172 1 1
TLR7 USP18 0 0 324 338 1 1
TLR7 MRPL17 0 0 0 167 1 1
TLR7 IL22RA1 0 0 150 173 1 1
TLR7 ATG10 0 0 160 159 1 2
TLR7 CXCL2 0 0 417 559 1 1
TLR7 LPHN1 0 0 53 186 1 1
TLR7 PARVG 0 0 62 565 1 1
TLR7 PTK7 0 0 0 189 1 1
TLR7 CCL20 0 0 459 459 1 1
TLR7 GFAP 0 0 170 185 1 2
TLR7 CXCR6 0 0 171 189 1 1
TLR7 ACTG1 0 0 181 265 1 1
TLR7 CCL23 0 0 138 184 1 1
TLR7 SNRNP40 0 0 0 156 1 1
TLR7 IKZF1 0 0 176 626 1 1
TLR7 KIAA1210 0 0 0 155 1 1
TLR7 ATG7 0 0 275 301 1 2
TLR7 DHX8 0 0 0 327 1 1
TLR7 TGFBR2 0 0 113 176 1 1
TLR7 TJP1 0 0 156 157 1 1
TLR7 SELE 0 0 310 368 1 1
TLR7 TRAT1 0 0 325 359 1 1
TLR7 HTR2B 0 0 81 176 1 1
TLR7 TAC1 0 0 150 168 1 1
TLR7 GPR174 0 0 56 555 1 1
TLR7 ICAM3 0 0 270 285 1 1
TLR7 RPS13 0 0 50 157 1 1
TLR7 NRXN1 0 0 0 153 1 1
TLR7 GPR132 0 0 90 236 1 1
TLR7 ITGA2B 0 0 143 159 1 1
TLR7 DNASE1L3 0 0 231 299 1 1
TLR7 THBD 0 0 509 509 1 1
TLR7 IL23A 0 0 426 426 1 1
TLR7 TYRO3 0 0 180 221 1 1
TLR7 MRPL21 0 0 0 167 1 1
TLR7 CD226 0 0 181 211 1 1
TLR7 SH3BP1 0 0 0 242 1 1
TLR7 MAPK14 0 0 292 354 1 2
TLR7 CSF3R 0 0 181 323 1 1
TLR7 S1PR1 0 0 181 206 1 1
TLR7 SYK 0 0 503 585 1 2
TLR7 LEP 0 0 155 154 1 1
TLR7 NFKBIA 0 0 519 548 1 2
TLR7 WT1 0 0 140 157 1 1
TLR7 MAP3K3 0 0 155 276 1 1
TLR7 ATAD2B 0 0 0 163 1 1
TLR7 ZC3H12A 0 0 185 215 1 1
TLR7 LSM10 0 0 0 154 1 1
TLR7 TCF4 0 0 343 354 1 1
TLR7 FCER1G 0 0 297 397 1 1
TLR7 TRAF7 0 0 167 186 1 1
TLR7 CASP5 0 0 158 288 1 1
TLR7 TREML4 0 0 261 303 1 1
TLR7 SIGLEC8 0 0 167 261 1 1
TLR7 PTEN 0 0 233 287 1 2
TLR7 MBP 0 0 155 168 1 2
TLR7 TENM1 0 0 0 168 1 1
TLR7 IRF4 0 0 457 506 1 1
TLR7 VEGFA 0 0 400 400 1 2
TLR7 SNIP1 0 0 0 166 1 1
TLR7 LRR1 0 0 180 213 1 1
TLR7 HSPA1B 0 0 0 201 1 1
TLR7 CXCL1 0 0 469 598 1 2
TLR7 IL33 0 0 459 470 1 2
TLR7 PSMB9 0 0 202 258 1 1
TLR7 CCL11 0 0 323 413 1 1
TLR7 CLEC4M 0 0 245 273 1 1
TLR7 AICDA 0 0 414 431 1 1
TLR7 TNFRSF21 0 0 204 204 1 1
TLR7 IL1RL1 0 0 265 281 1 1
TLR7 TBC1D9 0 0 0 155 1 1
TLR7 PGLYRP1 0 0 160 159 1 1
TLR7 CD1B 0 0 341 341 1 1
TLR7 ATG12 0 0 293 293 1 2
TLR7 ALOX5 0 0 134 189 1 1
TLR7 HEATR6 0 0 0 211 1 1
TLR7 ANG 0 0 90 152 1 2
TLR7 NOTCH2 0 0 135 180 1 1
TLR7 IFNA5 0 0 283 309 1 1
TLR7 PPIA 0 0 193 275 1 1
TLR7 CXCL5 0 0 307 506 1 1
TLR7 TRIM56 0 0 210 239 1 1
TLR7 VSIG1 0 0 0 155 1 1
TLR7 CD28 0 0 470 502 1 1
TLR7 CD5 0 0 310 339 1 1
TLR7 SLC11A1 0 0 207 300 1 1
TLR7 BLK 0 0 256 647 1 1
TLR7 ITGAX 0 0 732 770 1 1
TLR7 FOLH1 0 0 138 152 1 1
TLR7 SFN 0 0 0 161 1 2
TLR7 SOCS2 0 0 193 205 1 1
TLR7 CASP4 0 0 194 284 1 2
TLR7 PTPN12 0 0 0 374 1 1
TLR7 S100A12 0 0 124 200 1 1
TLR7 CXorf23 0 0 0 319 1 1
TLR7 CHUK 0 0 556 583 1 1
TLR7 SAMHD1 0 0 392 459 1 1
TLR7 IFIT1B 0 0 81 161 1 1
TLR7 STK24 0 0 0 182 1 1
TLR7 HMGB3 0 0 539 539 1 1
TLR7 HCK 0 0 155 308 1 1
TLR7 CSF1 0 0 457 468 1 1
TLR7 TRIM68 0 0 83 153 1 1
TLR7 MSRB1 0 0 0 151 1 1
TLR7 PRDM1 0 0 362 377 1 1
TLR7 YWHAH 0 0 0 161 1 1
TLR7 CLEC9A 0 0 492 524 1 1
TLR7 IL15RA 0 0 156 155 1 1
TLR7 MATK 0 0 90 198 1 1
TLR7 FOS 0 0 293 313 1 2
TLR7 S100A8 0 0 123 174 1 2
TLR7 YWHAZ 0 0 81 195 1 1
TLR7 CCL27 0 0 218 218 1 1
TLR7 RAB11B 0 0 0 196 1 1
TLR7 FCER1A 0 0 249 288 1 1
TLR7 PTPN11 0 0 194 291 1 1
TLR7 SIGIRR 0 0 406 406 1 1
TLR7 IRAK3 0 0 518 587 1 1
TLR7 DDX31 0 0 0 163 1 1
TLR7 IRG1 0 0 357 371 1 1
TLR7 FTH1 0 0 66 159 1 1
TLR7 CCL8 0 0 310 419 1 1
TLR7 GBP6 0 0 108 150 1 1
TLR7 MID2 0 0 74 161 1 1
TLR7 NRAS 0 0 74 155 1 1
TLR7 HSPA5 0 0 113 176 1 2
TLR7 CCL17 0 0 286 301 1 1
TLR7 IFNGR1 0 0 341 372 1 1
TLR7 RNASE3 0 0 141 160 1 1
TLR7 ARF6 0 0 91 170 1 1
TLR7 NFAM1 0 0 73 181 1 1
TLR7 SF3B3 0 0 81 276 1 1
TLR7 CCL7 0 0 380 413 1 1
TLR7 NR6A1 0 0 0 172 1 1
TLR7 STK38L 0 0 0 167 1 1
TLR7 SDC1 0 0 373 373 1 1
TLR7 LRRK2 0 0 122 227 1 2
TLR7 TOLLIP 0 0 405 405 1 1
TLR7 TRAF3 0 0 612 652 1 2
TLR7 LILRA4 0 0 572 618 1 1
TLR7 RPL3L 0 0 0 165 1 1
TLR7 IFITM5 0 0 123 202 1 1
TLR7 PIK3CB 0 0 60 182 1 1
TLR7 TLR2 0 0 870 436 1 2
TLR7 ENSG00000277117 0 0 402 424 1 1
TLR7 CD86 0 0 700 787 1 1
TLR7 NHP2 0 0 0 171 1 1
TLR7 WAS 0 0 151 244 1 1
TLR7 NOD1 0 0 618 640 1 2
TLR7 CFB 0 0 181 217 1 1
TLR7 DROSHA 0 0 217 240 1 1
TLR7 KIR2DL3 0 0 163 163 1 1
TLR7 EDF1 0 0 0 156 1 1
TLR7 TRIM69 0 0 120 196 1 1
TLR7 CD247 0 0 242 291 1 1
TLR7 AQR 0 0 0 167 1 1
TLR7 BMX 0 0 70 160 1 1
TLR7 CLDN1 0 0 112 175 1 1
TLR7 ENSG00000279392 0 0 134 150 1 1
TLR7 NLRC4 0 0 469 508 1 2
TLR7 SECISBP2L 0 0 325 325 1 1
TLR7 DUOX1 0 0 97 171 1 1
TLR7 F13A1 0 0 45 193 1 1
TLR7 SNRPB2 0 0 0 219 1 1
TLR7 CIRBP 0 0 61 160 1 1
TLR7 FAS 0 0 325 517 1 2
TLR7 INPP5D 0 0 234 530 1 1
TLR7 CCL14 0 0 122 223 1 1
TLR7 VCAM1 0 0 325 657 1 1
TLR7 IFIT3 0 0 360 418 1 1
TLR7 SPIB 0 0 310 343 1 1
TLR7 DDX10 0 0 0 163 1 1
TLR7 SF3A3 0 0 0 224 1 1
TLR7 CSF2 0 0 662 667 1 1
TLR7 ACKR1 0 0 155 154 1 1
TLR7 CD34 0 0 372 385 1 2
TLR7 UBA7 0 0 103 177 1 1
TLR7 NGF 0 0 171 201 1 2
TLR7 KAL1 0 0 0 157 1 1
TLR7 MRGPRD 0 0 91 185 1 1
TLR7 ISY1 0 0 0 189 1 1
TLR7 TNFSF8 0 0 134 194 1 1
TLR7 PRKRA 0 0 308 307 1 1
TLR7 PIK3R6 0 0 0 158 1 1
TLR7 GPR183 0 0 212 352 1 1
TLR7 CXorf21 0 0 341 561 1 1
TLR7 PTPN23 0 0 0 154 1 1
TLR7 DDX56 0 0 240 288 1 1
TLR7 AXL 0 0 243 296 1 2
TLR7 EIF4EBP1 0 0 95 153 1 2
TLR7 XAB2 0 0 0 211 1 1
TLR7 CYLD 0 0 260 274 1 1
TLR7 GPT 0 0 218 231 1 1
TLR7 IFNGR2 0 0 244 243 1 1
TLR7 BCL6 0 0 336 363 1 1
TLR7 PPP3CA 0 0 0 182 1 1
TLR7 CD58 0 0 218 218 1 1
TLR7 CCR8 0 0 150 168 1 1
TLR7 FCRL5 0 0 206 234 1 1
TLR7 SERPINB7 0 0 0 309 1 1
TLR7 MAP3K19 0 0 0 179 1 1
TLR7 MYO1E 0 0 0 224 1 1
TLR7 RNASE7 0 0 123 202 1 1
TLR7 SERPINB3 0 0 0 288 1 1
TLR7 P2RY13 0 0 61 172 1 1
TLR7 TLR3 0 500 913 698 1 2
TLR7 RSAD2 0 0 613 642 1 1
TLR7 IL19 0 0 182 181 1 1
TLR7 MIF 0 0 212 212 1 2
TLR7 ATG3 0 0 293 293 1 2
TLR7 RGS18 0 0 54 554 1 1
TLR7 CD52 0 0 164 250 1 1
TLR7 CD180 0 0 390 372 1 1
TLR7 CD93 0 0 227 287 1 1
TLR7 ADA 0 0 207 224 1 1
TLR7 IRF8 0 0 510 595 1 1
TLR7 CD3G 0 0 125 205 1 1
TLR7 RAG1 0 0 260 260 1 1
TLR7 CDC42 0 0 135 265 1 2
TLR7 MRPL4 0 0 0 163 1 1
TLR7 RNPC3 0 0 0 219 1 1
TLR7 TNFSF11 0 0 246 265 1 2
TLR7 APOE 0 0 253 269 1 2
TLR7 TRPV2 0 0 48 177 1 1
TLR7 FOXO3 0 0 150 165 1 2
TLR7 RIPK3 0 0 397 455 1 2
TLR7 PRPF3 0 0 0 163 1 1
TLR7 PRKCD 0 0 166 184 1 2
TLR7 CDKL5 0 0 0 155 1 1
TLR7 KLF8 0 0 45 202 1 1
TLR7 RAB7B 0 0 218 308 1 1
TLR7 STAT5B 0 0 285 314 1 1
TLR7 MRPS9 0 0 0 167 1 1
TLR7 HRH4 0 0 142 160 1 1
TLR7 TGFB1 0 0 156 245 1 2
TLR7 PACSIN1 0 0 203 298 1 1
TLR7 MARCH5 0 0 171 438 1 1
TLR7 RAC2 0 0 120 310 1 1
TLR7 RAB11A 0 0 125 289 1 2
TLR7 KLRB1 0 0 195 260 1 1
TLR7 LILRA2 0 0 155 223 1 1
TLR7 AGTR2 0 0 181 181 1 1
TLR7 PLRG1 0 0 0 229 1 1
TLR7 RARRES2 0 0 158 157 1 1
TLR7 KDR 0 0 138 199 1 2
TLR7 IL4I1 0 0 88 153 1 1
TLR7 FOXP3 0 0 565 602 1 2
TLR7 YTHDC2 0 0 0 158 1 1
TLR7 PTPN6 0 0 171 297 1 1
TLR7 TBK1 0 0 667 738 1 2
TLR7 CLEC5A 0 0 324 383 1 1
TLR7 PECAM1 0 0 203 250 1 1
TLR7 MARCH1 0 0 120 243 1 1
TLR7 PTK2B 0 0 96 171 1 1
TLR7 LCP1 0 0 0 289 1 1
TLR7 LST1 0 0 81 174 1 1
TLR7 ENSG00000264813 0 0 129 216 1 1
TLR7 FSTL1 0 0 562 562 1 1
TLR7 MOB3A 0 0 0 198 1 1
TLR7 CD46 0 0 242 241 1 2
TLR7 FCAR 0 0 184 209 1 1
TLR7 CD38 0 0 417 454 1 2
TLR7 SNRPF 0 0 0 224 1 1
TLR7 SNRPC 0 0 45 181 1 1
TLR7 LDLR 0 0 184 196 1 2
TLR7 TIMD4 0 0 202 228 1 1
TLR7 LPHN2 0 0 0 176 1 1
TLR7 AGXT 0 0 97 154 1 1
TLR7 CCND1 0 0 161 174 1 2
TLR7 CD36 0 0 72 195 1 2
TLR7 PTAFR 0 0 187 422 1 1
TLR7 VNN2 0 0 0 162 1 1
TLR7 NCF1 0 0 233 336 1 1
TLR7 BLNK 0 0 279 339 1 1
TLR7 IRAK2 0 600 527 824 1 1
TLR7 CD19 0 0 602 637 1 1
TLR7 ASCC3 0 0 0 185 1 1
TLR7 ICAM2 0 0 157 199 1 1
TLR7 PTPRE 0 0 0 171 1 1
TLR7 SIGLEC10 0 0 138 266 1 1
TLR7 IFIT2 0 0 464 506 1 1
TLR7 CD207 0 0 503 533 1 1
TLR7 MGA 0 0 162 187 1 1
TLR7 FAM46A 0 0 136 159 1 1
TLR7 RRAD 0 0 128 235 1 1
TLR7 CCDC94 0 0 0 180 1 1
TLR7 YWHAQ 0 0 0 161 1 1
TLR7 DRP2 0 0 0 165 1 1
TLR7 DMTF1 0 0 0 171 1 1
TLR7 EIF4E 0 0 123 153 1 2
TLR7 DHX30 0 0 0 158 1 1
TLR7 PPP2CA 0 0 45 185 1 1
TLR7 HIST2H2BE 0 0 183 195 1 1
TLR7 SLPI 0 0 207 224 1 1
TLR7 MAPK1 0 0 152 173 1 2
TLR7 IGF1 0 0 157 175 1 2
TLR7 DEFB4A 0 0 407 407 1 1
TLR7 WDFY3 0 0 53 340 1 2
TLR7 APOB 0 0 157 185 1 2
TLR7 CSF1R 0 0 391 734 1 1
TLR7 MOB1B 0 0 0 154 1 1
TLR7 SOCS1 0 0 468 476 1 1
TLR7 RAB39A 0 0 50 152 1 1
TLR7 BTK 0 0 599 692 1 1
TLR7 CD6 0 0 122 166 1 1
TLR7 PRPF8 0 0 0 219 1 1
TLR7 GBP5 0 0 149 191 1 1
TLR7 FGF2 0 0 152 151 1 2
TLR7 IL31RA 0 0 138 231 1 1
TLR7 TIGIT 0 0 161 181 1 1
TLR7 CXCL3 0 0 260 440 1 1
TLR7 PPEF2 0 0 0 182 1 1
TLR7 RELB 0 0 341 341 1 2
TLR7 BCL2A1 0 0 124 583 1 1
TLR7 TNFSF14 0 0 113 172 1 1
TLR7 CD63 0 0 206 206 1 2
TLR7 CD2AP 0 0 161 167 1 1
TLR7 VWF 0 0 150 261 1 1
TLR7 ASB11 0 0 0 276 1 1
TLR7 ENSG00000272980 0 0 386 423 1 1
TLR7 CUL4B 0 0 0 151 1 1
TLR7 IFNAR1 0 0 681 704 1 1
TLR7 CISD3 0 0 0 167 1 1
TLR7 POTEI 0 0 0 156 1 1
TLR7 CMKLR1 0 0 234 278 1 1
TLR7 TBC1D10C 0 0 48 184 1 1
TLR7 IL23R 0 0 293 293 1 1
TLR7 NMB 0 0 127 181 1 1
TLR7 DDX3X 0 0 244 334 1 1
TLR7 ABCA6 0 0 0 177 1 1
TLR7 CD300LF 0 0 105 214 1 1
TLR7 FGD2 0 0 0 183 1 1
TLR7 IFI30 0 0 150 214 1 1
TLR7 TRAF3IP3 0 0 0 542 1 1
TLR7 HERC6 0 0 90 161 1 1
TLR7 CD209 0 0 563 594 1 1
TLR7 IL7 0 0 413 412 1 1
TLR7 CD44 0 0 390 403 1 2
TLR7 BDNF 0 0 144 175 1 2
TLR7 ATP11C 0 0 60 190 1 1
TLR7 LUC7L3 0 0 0 183 1 1
TLR7 TANK 0 0 582 591 1 2
TLR7 HNRNPD 0 0 57 188 1 1
TLR7 HLA-DMA 0 0 181 211 1 1
TLR7 TIRAP 0 0 735 735 1 1
TLR7 HSPA2 0 0 0 165 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0003725 Molecular Function double-stranded RNA binding enables IDA
GO:0038187 Molecular Function pattern recognition receptor activity enables IBA
GO:0005515 Molecular Function protein binding enables IPI
GO:0035197 Molecular Function siRNA binding enables ISS
GO:0003727 Molecular Function single-stranded RNA binding enables IMP
GO:0003727 Molecular Function single-stranded RNA binding enables ISS
GO:0007252 Biological Process I-kappaB phosphorylation involved_in IDA
GO:0007254 Biological Process JNK cascade involved_in IEA
GO:0007249 Biological Process canonical NF-kappaB signal transduction involved_in IBA
GO:0007249 Biological Process canonical NF-kappaB signal transduction involved_in IMP
GO:0071260 Biological Process cellular response to mechanical stimulus involved_in IEP
GO:0098586 Biological Process cellular response to virus involved_in IEA
GO:0051607 Biological Process defense response to virus involved_in IBA
GO:0051607 Biological Process defense response to virus involved_in IEP
GO:0051607 Biological Process defense response to virus involved_in IMP
GO:0006954 Biological Process inflammatory response involved_in IEA
GO:0045087 Biological Process innate immune response involved_in IMP
GO:0032722 Biological Process positive regulation of chemokine production involved_in IDA
GO:0050729 Biological Process positive regulation of inflammatory response involved_in IC
GO:0032727 Biological Process positive regulation of interferon-alpha production involved_in IDA
GO:0032728 Biological Process positive regulation of interferon-beta production involved_in IDA
GO:0032755 Biological Process positive regulation of interleukin-6 production involved_in IBA
GO:0032757 Biological Process positive regulation of interleukin-8 production involved_in IDA
GO:0032757 Biological Process positive regulation of interleukin-8 production involved_in IMP
GO:0060907 Biological Process positive regulation of macrophage cytokine production involved_in IEA
GO:1901224 Biological Process positive regulation of non-canonical NF-kappaB signal transduction involved_in IDA
GO:0045944 Biological Process positive regulation of transcription by RNA polymerase II involved_in IEA
GO:0032729 Biological Process positive regulation of type II interferon production involved_in IDA
GO:0001932 Biological Process regulation of protein phosphorylation involved_in IEA
GO:0070305 Biological Process response to cGMP involved_in IMP
GO:0034154 Biological Process toll-like receptor 7 signaling pathway involved_in IBA
GO:0002224 Biological Process toll-like receptor signaling pathway involved_in IBA
GO:0000139 Cellular Component Golgi membrane located_in TAS
GO:0005737 Cellular Component cytoplasm located_in IDA
GO:0032009 Cellular Component early phagosome located_in ISS
GO:0036020 Cellular Component endolysosome membrane located_in TAS
GO:0005783 Cellular Component endoplasmic reticulum located_in ISS
GO:0005789 Cellular Component endoplasmic reticulum membrane located_in TAS
GO:0005768 Cellular Component endosome located_in ISS
GO:0010008 Cellular Component endosome membrane located_in TAS
GO:0005764 Cellular Component lysosome located_in ISS
GO:0005886 Cellular Component plasma membrane is_active_in IBA
GO:0005886 Cellular Component plasma membrane located_in IDA
GO:0043235 Cellular Component receptor complex part_of IDA
Pathways
Name DB ID
Disease Reactome R-HSA-1643685
Trafficking and processing of endosomal TLR Reactome R-HSA-1679131
Toll Like Receptor 9 (TLR9) Cascade Reactome R-HSA-168138
Toll Like Receptor 7/8 (TLR7/8) Cascade Reactome R-HSA-168181
Innate Immune System Reactome R-HSA-168249
Immune System Reactome R-HSA-168256
Toll-like Receptor Cascades Reactome R-HSA-168898
Infectious disease Reactome R-HSA-5663205
SARS-CoV-1 Infection Reactome R-HSA-9678108
Potential therapeutics for SARS Reactome R-HSA-9679191
SARS-CoV Infections Reactome R-HSA-9679506
SARS-CoV-1-host interactions Reactome R-HSA-9692914
SARS-CoV-1 activates/modulates innate immune responses Reactome R-HSA-9692916
SARS-CoV-2 Infection Reactome R-HSA-9694516
SARS-CoV-2 activates/modulates innate and adaptive immune responses Reactome R-HSA-9705671
SARS-CoV-2-host interactions Reactome R-HSA-9705683
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling Reactome R-HSA-975110
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation Reactome R-HSA-975138
MyD88 dependent cascade initiated on endosome Reactome R-HSA-975155
Viral Infection Pathways Reactome R-HSA-9824446
mRNA vaccine activation of dendritic cell and induction of IFN-1 (WP5187) WikiPathways WP5187_r122433
MYD88 distinct input-output pathway (WP3877) WikiPathways WP3877_r117828
Measles virus infection (WP4630) WikiPathways WP4630_r123414
Toll-like receptor signaling related to MyD88 (WP3858) WikiPathways WP3858_r117850
Platelet-mediated interactions with vascular and circulating cells (WP4462) WikiPathways WP4462_r102079
Extrafollicular and follicular B cell activation by SARS-CoV-2 (WP5218) WikiPathways WP5218_r124690
SARS-CoV-2 and COVID-19 pathway (WP4846) WikiPathways WP4846_r124663
Type I interferon induction and signaling during SARS-CoV-2 infection (WP4868) WikiPathways WP4868_r124657
SARS-CoV-2 innate immunity evasion and cell-specific immune response (WP5039) WikiPathways WP5039_r124653
Burn wound healing (WP5055) WikiPathways WP5055_r122621
miRNAs involvement in the immune response in sepsis (WP4329) WikiPathways WP4329_r123505
Toll-like receptor signaling pathway (WP75) WikiPathways WP75_r119233
Mitochondrial immune response to SARS-CoV-2 (WP5038) WikiPathways WP5038_r124641
Interactions between immune cells and microRNAs in tumor microenvironment (WP4559) WikiPathways WP4559_r104316
Host-pathogen interaction of human coronaviruses - interferon induction (WP4880) WikiPathways WP4880_r124638
Transcripts
Accession Version MolecularType Name NCBI Comments
NM_016562 4 mRNA None NC_000023 Reference