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PDPK1

3-phosphoinositide dependent protein kinase 1
General Information
Name 3-phosphoinositide dependent protein kinase 1
Alias
  • 3-phosphoinositide-dependent protein kinase 1
  • 3-phosphoinositide-dependent protein kinase 2 pseudogene
  • PkB kinase like gene 1
  • Putative 3-phosphoinositide-dependent protein kinase 2
Gene_family AGC family kinases
organism Homo sapiens
entrez_id 5170
location 16p13.3
transcript_count 11
exon_count 17
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez Enables 3-phosphoinositide-dependent protein kinase activity; phospholipase activator activity; and phospholipase binding activity. Involved in several processes, including cell surface receptor signaling pathway; regulation of protein kinase activity; and regulation of signal transduction. Acts upstream of or within intracellular signal transduction. Located in cell projection; cytosol; and plasma membrane. Implicated in prostate cancer. Biomarker of lung non-small cell carcinoma. [provided by Alliance of Genome Resources, Apr 2022]
    Stringdb 3-phosphoinositide-dependent protein kinase 1; Serine/threonine kinase which acts as a master kinase, phosphorylating and activating a subgroup of the AGC family of protein kinases. Its targets include: protein kinase B (PKB/AKT1, PKB/AKT2, PKB/AKT3), p70 ribosomal protein S6 kinase (RPS6KB1), p90 ribosomal protein S6 kinase (RPS6KA1, RPS6KA2 and RPS6KA3), cyclic AMP-dependent protein kinase (PRKACA), protein kinase C (PRKCD and PRKCZ), serum and glucocorticoid-inducible kinase (SGK1, SGK2 and SGK3), p21-activated kinase-1 (PAK1), protein kinase PKN (PKN1 and PKN2). Plays a central rol [...]
    nextProt Is catalytically inactive.
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
PDPK1 BioGRID YWHAZ GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
PDPK1 BioGRID YWHAH GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
PDPK1 BioGRID YWHAE GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-localization
PDPK1 BioGRID YWHAB GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
PDPK1 BioGRID ACE2 GeneID BioGRID Proximity Label-MS
PDPK1 BioGRID PRKCB GeneID BioGRID Affinity Capture-Western; Co-localization; Reconstituted Complex
PDPK1 BioGRID GNB1 GeneID BioGRID Affinity Capture-Western
PDPK1 BioGRID N GeneID BioGRID Affinity Capture-Western
PDPK1 BioGRID M GeneID BioGRID Affinity Capture-Western
PDPK1 BioGRID RASSF3 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID AKT1 GeneID BioGRID Affinity Capture-Luminescence; Affinity Capture-Western; Biochemical Activity; Co-localization
PDPK1 BioGRID ACOT9 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID PALM2AKAP2 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID YWHAQ GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
PDPK1 BioGRID YWHAG GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID UTRN GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID SNTB2 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID PRKAR2B GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID PPP2R2A GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID INCENP GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID SFN GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID DFFB GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID M GeneID BioGRID Affinity Capture-Western
PDPK1 BioGRID TRIM67 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID PDPK2P GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID AGRN GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID EGFLAM GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID OSBPL8 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID C17orf80 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID ZRANB1 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID GPC6 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID HS2ST1 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID ROCK2 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID NRXN3 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID SQSTM1 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID NRP1 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID TMEFF1 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID TPP2 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID TGFBR3 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID SDC4 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID SDC2 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID SDC1 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID HADHB GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID HADHA GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID GPC1 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID GLG1 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID GPC3 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID FGF2 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID GPC4 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID AHSG GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID RBKS GeneID BioGRID Co-fractionation
PDPK1 BioGRID UBFD1 GeneID BioGRID Co-fractionation
PDPK1 BioGRID CARMIL1 GeneID BioGRID Co-fractionation
PDPK1 BioGRID SEC31A GeneID BioGRID Co-fractionation
PDPK1 BioGRID NR2F2 GeneID BioGRID Co-fractionation
PDPK1 BioGRID SEC13 GeneID BioGRID Co-fractionation
PDPK1 BioGRID PSME1 GeneID BioGRID Co-fractionation
PDPK1 BioGRID PLS3 GeneID BioGRID Co-fractionation
PDPK1 BioGRID PCCB GeneID BioGRID Co-fractionation
PDPK1 BioGRID IDE GeneID BioGRID Co-fractionation
PDPK1 BioGRID MRI1 GeneID BioGRID Co-fractionation
PDPK1 BioGRID WDR5 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-crystal Structure; Co-localization; Protein-peptide; Reconstituted Complex
PDPK1 BioGRID PDPK1 GeneID BioGRID Affinity Capture-MS; Biochemical Activity
PDPK1 BioGRID KRAS GeneID BioGRID Negative Genetic
PDPK1 BioGRID EGFR GeneID BioGRID Negative Genetic
PDPK1 BioGRID CDSN GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID CASP3 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID GSK3B GeneID BioGRID Biochemical Activity
PDPK1 BioGRID CSNK1E GeneID BioGRID Affinity Capture-Western
PDPK1 BioGRID CSNK1D GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity
PDPK1 BioGRID CUL3 GeneID BioGRID Reconstituted Complex
PDPK1 BioGRID SPOP GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
PDPK1 BioGRID FAXC GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID TBL2 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID BAG2 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID CPA4 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID NRBP1 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID RBBP5 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID SERPINA4 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID COX2 GeneID BioGRID Affinity Capture-Western
PDPK1 BioGRID HSPA8 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID SLC31A1 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID ATG10 GeneID BioGRID Phenotypic Suppression
PDPK1 BioGRID MAP1LC3A GeneID BioGRID Affinity Capture-Western
PDPK1 BioGRID SENP3 GeneID BioGRID Affinity Capture-Western
PDPK1 BioGRID WIPI2 GeneID BioGRID Affinity Capture-Western
PDPK1 BioGRID ATG5 GeneID BioGRID Affinity Capture-Western
PDPK1 BioGRID UBE2I GeneID BioGRID Affinity Capture-Western; Biochemical Activity
PDPK1 BioGRID RPS6KB1 GeneID BioGRID Affinity Capture-Western
PDPK1 BioGRID PIK3C3 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
PDPK1 BioGRID GTF2I GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID FLNC GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID SLC29A1 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID DHX9 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID CHD4 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID CD44 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID ASPH GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID TMED7-TICAM2 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID TPTEP2-CSNK1E GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID CAVIN1 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID SNX18 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID IMMP2L GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID GRPEL1 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID TBC1D15 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID CAMSAP3 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID DDX24 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID LRRC59 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID TMEM161A GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID PRPF31 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID TCF25 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID CDC37 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID HSPH1 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID LRPPRC GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID ARPC5 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID AKAP12 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID GTF3C5 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID MTA1 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID IQGAP1 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID CHAF1B GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID USP7 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID UQCRC2 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID UQCRC1 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID RPL38 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID PRKCI GeneID BioGRID Affinity Capture-MS; Reconstituted Complex; Two-hybrid
PDPK1 BioGRID POLRMT GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID POLR2A GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID JUP GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID HSPG2 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID HSPA9 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID HSPA6 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID HSPA5 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID HSPA4 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID HSPA1A GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID PLEKHA4 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID TANK GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID VIRMA GeneID BioGRID Affinity Capture-RNA
PDPK1 BioGRID Akt1 GeneID BioGRID Biochemical Activity
PDPK1 BioGRID AKT2 GeneID BioGRID Affinity Capture-Western
PDPK1 BioGRID FAM199X GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID SCRN2 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID MAP3K7 GeneID BioGRID Affinity Capture-Western
PDPK1 BioGRID RPS6KA3 GeneID BioGRID Affinity Capture-Western; Co-localization
PDPK1 BioGRID XPO1 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID Cct2 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID Kctd5 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID APBB3 GeneID BioGRID Two-hybrid
PDPK1 BioGRID CSK GeneID BioGRID Two-hybrid
PDPK1 BioGRID ZDHHC17 GeneID BioGRID Affinity Capture-Western; Two-hybrid
PDPK1 BioGRID SRPK1 GeneID BioGRID Biochemical Activity
PDPK1 BioGRID APP GeneID BioGRID Reconstituted Complex
PDPK1 BioGRID STRAP GeneID BioGRID Affinity Capture-Western
PDPK1 BioGRID SGK1 GeneID BioGRID Biochemical Activity; Reconstituted Complex
PDPK1 BioGRID SOCS3 GeneID BioGRID Two-hybrid
PDPK1 BioGRID PEA15 GeneID BioGRID Two-hybrid
PDPK1 BioGRID TCAP GeneID BioGRID Two-hybrid
PDPK1 BioGRID ZNF133 GeneID BioGRID Two-hybrid
PDPK1 BioGRID SMARCB1 GeneID BioGRID Two-hybrid
PDPK1 BioGRID SBF1 GeneID BioGRID Two-hybrid
PDPK1 BioGRID XRCC6 GeneID BioGRID Two-hybrid
PDPK1 BioGRID BLMH GeneID BioGRID Two-hybrid
PDPK1 BioGRID PRXL2B GeneID BioGRID Two-hybrid
PDPK1 BioGRID CARD11 GeneID BioGRID Affinity Capture-Western; Two-hybrid
PDPK1 BioGRID WDCP GeneID BioGRID Two-hybrid
PDPK1 BioGRID KATNBL1 GeneID BioGRID Two-hybrid
PDPK1 BioGRID PNO1 GeneID BioGRID Two-hybrid
PDPK1 BioGRID DDIT4 GeneID BioGRID Two-hybrid
PDPK1 BioGRID PHAX GeneID BioGRID Two-hybrid
PDPK1 BioGRID LUC7L2 GeneID BioGRID Two-hybrid
PDPK1 BioGRID ZC3HC1 GeneID BioGRID Two-hybrid
PDPK1 BioGRID GIT1 GeneID BioGRID Two-hybrid
PDPK1 BioGRID POLDIP2 GeneID BioGRID Two-hybrid
PDPK1 BioGRID XPO7 GeneID BioGRID Two-hybrid
PDPK1 BioGRID PRKCQ GeneID BioGRID Affinity Capture-Western
PDPK1 BioGRID G3BP1 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID PA2G4 GeneID BioGRID Affinity Capture-MS
PDPK1 BioGRID SND1 GeneID BioGRID Affinity Capture-MS
PDPK1 Protein RPS6KB2 GeneID HPRD
PDPK1 Protein RPS6KB1 GeneID HPRD
PDPK1 Protein CDAN1 GeneID HPRD
PDPK1 Protein AKTIP GeneID HPRD
PDPK1 Protein PRSS23 GeneID HPRD
PDPK1 Protein AKT3 GeneID HPRD
PDPK1 Protein SGK3 GeneID HPRD
PDPK1 Protein SGK2 GeneID HPRD
PDPK1 Protein CARD11 GeneID HPRD
PDPK1 Protein NHERF2 GeneID HPRD
PDPK1 Protein STRAP GeneID HPRD
PDPK1 Protein PDPK1 GeneID HPRD
PDPK1 Protein SGK1 GeneID HPRD
PDPK1 Protein PAK1 GeneID HPRD
PDPK1 Protein PKN2 GeneID HPRD
PDPK1 Protein PXN GeneID HPRD
PDPK1 Protein ILK GeneID HPRD
PDPK1 Protein RPS6KA1 GeneID HPRD
PDPK1 Protein PRKACA GeneID HPRD
PDPK1 Protein RALGDS GeneID HPRD
PDPK1 Protein MTOR GeneID HPRD
PDPK1 Protein PTK2B GeneID HPRD
PDPK1 Protein PKN1 GeneID HPRD
PDPK1 Protein PRKCI GeneID HPRD
PDPK1 Protein RPS6KA3 GeneID HPRD
PDPK1 Protein SRC GeneID HPRD
PDPK1 Protein PRKCD GeneID HPRD
PDPK1 Protein PRKCE GeneID HPRD
PDPK1 Protein PRKCB GeneID HPRD
PDPK1 Protein ITGB3 GeneID HPRD
PDPK1 Protein AKT2 GeneID HPRD
PDPK1 Protein AKT1 GeneID HPRD
PDPK1 Protein IRS1 GeneID HPRD
PDPK1 Protein YWHAQ GeneID HPRD
PDPK1 Protein HSP90AA1 GeneID HPRD
PDPK1 Protein YWHAH GeneID HPRD
PDPK1 BioGRID MAPK8 GeneID BioGRID Reconstituted Complex
PDPK1 BioGRID PRKCZ GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex; Two-hybrid
PDPK1 BioGRID ILK GeneID BioGRID Affinity Capture-Western
PDPK1 BioGRID PKN2 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
PDPK1 BioGRID PKN1 GeneID BioGRID Reconstituted Complex; Two-hybrid
PDPK1 BioGRID PRKACA GeneID BioGRID Reconstituted Complex; Two-hybrid
PDPK1 BioGRID PRKCD GeneID BioGRID Affinity Capture-Western; Two-hybrid
PDPK1 BioGRID NHERF2 GeneID BioGRID Affinity Capture-Western
PDPK1 BioGRID PRSS23 GeneID BioGRID Two-hybrid
PDPK1 Protein AKT1 GeneID BIND PDK1 phosphorylates Akt1.
PDPK1 None None None BIND An unspecified isoform of PDPK1 (PDK1) phosphorylates PRKCE (PKC-epsilon). This interaction was modeled on a demonstrated interaction between PDPK1 from an unspecified species and PRKCE from an unspecified species.
PDPK1 None None None BIND An unspecified isoform of PDPK1 (PDK1) phosphorylates PRKCZ (PKC-zeta). This interaction was modeled on a demonstrated interaction between PDPK1 from an unspecified species and PRKCZ from an unspecified species.
PDPK1 None None None BIND An unspecified isoform of PDPK1 (PDK1) interacts with and phosphorylates PRKCH (PKC-eta). This interaction was modeled on a demonstrated interaction between PDPK1 from an unspecified species and PRKCH from an unspecified species.
PDPK1 Protein PRKCQ GeneID BIND PDK1 interacts with PKC-theta.
PDPK1 Protein CARD11 GeneID BIND PDK1 interacts with CARD11.
PDPK1 Protein PRKCD GeneID BIND PRKCD (PKCD) interacts with PDPK1 (PDK1). This interaction was modelled on a demonstrated interaction between human PRKCD and rat PDPK1.
PDPK1 Protein PKN2 GeneID BIND PKN2 (PRK2) interacts with PDPK1 (PDK1). This interaction was modelled on a demonstrated interaction between human PKN2 and rat PDPK1.
PDPK1 Protein PRKCZ GeneID BIND PRKCZ (PKCZ) interacts with PDPK1 (PDK1). This interaction was modelled on a demonstrated interaction between human PRKCZ and rat PDPK1.
StringDB
A B experiments database textmining combined score hadb nhadb
PDPK1 LAT2 0 650 0 650 1 1
PDPK1 GLTP 0 0 0 157 1 1
PDPK1 DCX 0 0 47 150 1 1
PDPK1 BIN1 0 0 46 165 1 1
PDPK1 LRRK1 0 0 0 196 1 1
PDPK1 TBK1 0 0 180 233 1 2
PDPK1 TBPL2 0 0 0 169 1 1
PDPK1 RAC2 0 650 145 719 1 1
PDPK1 INPP5J 0 0 81 162 1 1
PDPK1 RRAGA 0 0 167 252 1 1
PDPK1 JAK1 0 0 136 200 1 2
PDPK1 MOS 0 0 0 247 1 1
PDPK1 KDR 0 0 422 216 1 2
PDPK1 EIF2S1 0 0 137 409 1 2
PDPK1 TESK2 0 0 0 163 1 1
PDPK1 SBF2 0 0 0 172 1 1
PDPK1 TGFB1 0 900 95 907 1 2
PDPK1 VDAC1 0 0 134 221 1 2
PDPK1 PIK3C2A 0 0 242 490 1 1
PDPK1 TSC2 0 650 519 893 1 2
PDPK1 CNBD2 0 0 0 271 1 1
PDPK1 STAT5B 0 0 126 235 1 1
PDPK1 TRRAP 0 0 0 234 1 1
PDPK1 RIPK3 0 0 0 164 1 2
PDPK1 CAMK1G 0 0 0 183 1 1
PDPK1 PIP4K2B 0 0 84 243 1 1
PDPK1 CDKN1B 0 650 206 710 1 2
PDPK1 UBR1 0 0 0 171 1 1
PDPK1 STK3 0 0 135 247 1 1
PDPK1 PRKCD 462 900 317 966 1 2
PDPK1 PGP 0 0 0 207 1 1
PDPK1 USP7 131 0 0 155 1 1
PDPK1 EIF4H 0 0 47 231 1 1
PDPK1 BOLA2-SMG1P6 0 0 0 306 1 1
PDPK1 ACTG2 0 0 0 161 1 1
PDPK1 CRIP2 0 0 0 183 1 1
PDPK1 FOXO3 0 0 425 792 1 2
PDPK1 SLC2A4 0 0 392 425 1 1
PDPK1 YWHAB 131 0 75 326 1 1
PDPK1 RNASEH1 0 0 54 150 1 1
PDPK1 ZNF705A 0 0 267 267 1 1
PDPK1 SCD 0 0 73 174 1 1
PDPK1 SRC 213 900 579 951 1 2
PDPK1 IRS4 0 0 161 310 1 1
PDPK1 EPHB3 0 0 0 163 1 1
PDPK1 CDC42 0 0 218 306 1 2
PDPK1 ATG3 0 0 119 193 1 2
PDPK1 PORCN 0 0 66 216 1 1
PDPK1 BIRC6 0 0 0 170 1 1
PDPK1 TXNDC9 0 0 272 272 1 1
PDPK1 STK25 0 0 0 158 1 1
PDPK1 TEN1-CDK3 0 0 74 193 1 1
PDPK1 RASA3 0 0 90 315 1 1
PDPK1 MAP3K19 0 0 0 155 1 1
PDPK1 ACLY 0 0 162 163 1 1
PDPK1 KIAA1804 0 0 66 178 1 1
PDPK1 SSRP1 0 0 62 185 1 1
PDPK1 SIRT4 0 0 113 209 1 1
PDPK1 SLC2A8 0 0 95 189 1 1
PDPK1 GSK3A 0 650 183 766 1 1
PDPK1 HSP90AB1 0 0 108 182 1 2
PDPK1 FOXO4 0 0 261 289 1 1
PDPK1 AXL 0 0 101 185 1 2
PDPK1 HMCES 0 0 95 278 1 1
PDPK1 MALT1 0 900 98 907 1 1
PDPK1 RHOC 0 600 96 704 1 1
PDPK1 EIF4EBP1 0 0 466 525 1 2
PDPK1 PIKFYVE 0 0 147 222 1 2
PDPK1 AIFM1 0 0 97 227 1 1
PDPK1 MRPL9 0 0 112 154 1 1
PDPK1 MAP3K1 0 0 107 174 1 1
PDPK1 CDK15 0 0 0 199 1 1
PDPK1 PIK3R6 0 800 0 800 1 1
PDPK1 LARP4B 0 0 0 171 1 1
PDPK1 ERBB2 0 0 335 207 1 2
PDPK1 NGF 0 0 151 150 1 2
PDPK1 ACVR1B 0 0 48 176 1 1
PDPK1 YES1 0 0 57 190 1 1
PDPK1 PPARG 0 0 261 261 1 2
PDPK1 CDC42BPA 0 0 0 168 1 1
PDPK1 TYSND1 0 0 0 167 1 1
PDPK1 AKT1 907 900 984 995 1 2
PDPK1 DCAF8L1 0 0 0 192 1 1
PDPK1 C2orf76 0 0 0 169 1 1
PDPK1 FOXA1 0 0 49 270 1 1
PDPK1 CDK18 0 0 0 172 1 1
PDPK1 SYNJ2 0 0 56 218 1 1
PDPK1 SGK3 213 800 401 946 1 1
PDPK1 INPP5D 0 0 123 201 1 1
PDPK1 WDTC1 0 0 0 158 1 1
PDPK1 CD4 0 0 154 153 1 2
PDPK1 NTRK2 0 0 167 210 1 1
PDPK1 GDI2 0 0 46 225 1 1
PDPK1 KCNAB2 0 0 351 351 1 1
PDPK1 PHKG1 0 0 75 164 1 1
PDPK1 IKBKB 0 900 195 918 1 2
PDPK1 BMX 0 0 150 204 1 1
PDPK1 DROSHA 0 0 96 261 1 1
PDPK1 PHKG2 0 0 0 156 1 1
PDPK1 NOX4 0 0 139 172 1 2
PDPK1 ARF4 0 0 0 237 1 1
PDPK1 CTC1 0 0 49 151 1 1
PDPK1 PPP2R4 0 0 322 327 1 1
PDPK1 XIAP 0 0 180 268 1 2
PDPK1 PDK3 0 0 51 288 1 1
PDPK1 UBR2 0 0 0 178 1 1
PDPK1 DCUN1D3 0 0 0 154 1 1
PDPK1 DNAJC6 0 0 0 233 1 1
PDPK1 SMARCD1 0 0 0 236 1 1
PDPK1 STK32C 0 0 0 488 1 1
PDPK1 EPHB6 0 0 60 170 1 1
PDPK1 TNF 0 0 213 217 1 2
PDPK1 SNAP25 0 0 0 155 1 1
PDPK1 DMPK 0 0 0 161 1 1
PDPK1 AKAP6 0 0 432 432 1 1
PDPK1 CDC42BPB 0 0 0 168 1 1
PDPK1 BDNF 0 0 167 167 1 2
PDPK1 CD44 231 0 129 301 1 2
PDPK1 ITK 0 0 81 178 1 1
PDPK1 TSHR 0 0 67 209 1 1
PDPK1 VDR 0 0 0 188 1 2
PDPK1 PIK3R2 0 800 359 915 1 1
PDPK1 DCBLD2 0 0 122 322 1 1
PDPK1 RP1 0 0 0 303 1 1
PDPK1 LEO1 0 0 0 156 1 1
PDPK1 XPO6 0 0 0 174 1 1
PDPK1 PNPLA6 0 0 0 156 1 1
PDPK1 ANKK1 0 0 0 164 1 1
PDPK1 ACVR2A 0 0 48 196 1 1
PDPK1 TSSK1B 0 0 62 193 1 1
PDPK1 C14orf6 0 0 240 239 1 1
PDPK1 C11orf30 0 0 0 152 1 1
PDPK1 CDK3 0 0 74 193 1 1
PDPK1 EEF2 0 0 149 229 1 2
PDPK1 ITCH 0 0 63 156 1 1
PDPK1 RBM8A 0 0 67 165 1 1
PDPK1 STT3B 0 0 61 204 1 1
PDPK1 IGBP1 0 0 0 257 1 1
PDPK1 SMPD2 0 0 0 307 1 1
PDPK1 CCND2 0 0 167 178 1 1
PDPK1 CUL4B 0 0 45 203 1 1
PDPK1 TFRC 0 0 109 181 1 1
PDPK1 MAP3K14 0 0 0 157 1 1
PDPK1 RPS6KA2 0 900 502 937 1 1
PDPK1 GCG 0 0 161 161 1 1
PDPK1 POTEI 0 0 0 162 1 1
PDPK1 TMEM140 0 0 95 187 1 1
PDPK1 GNG13 0 650 0 650 1 1
PDPK1 PIK3C2G 0 0 124 317 1 1
PDPK1 RND3 0 0 438 460 1 1
PDPK1 SOS1 0 650 193 730 1 1
PDPK1 FGF2 117 0 162 228 1 2
PDPK1 PLEKHA4 270 0 127 335 1 1
PDPK1 FKBP1C 0 0 0 175 1 1
PDPK1 CSNK2A1 0 0 195 255 1 1
PDPK1 CDK17 0 0 0 184 1 1
PDPK1 EPHB4 0 0 0 163 1 1
PDPK1 PKM 128 0 170 245 1 1
PDPK1 ROR2 0 0 0 163 1 1
PDPK1 PPP2R5C 0 0 57 210 1 1
PDPK1 ENSG00000132716 0 0 88 234 1 1
PDPK1 PPP2R2B 270 0 74 355 1 1
PDPK1 CYTH3 0 0 113 176 1 1
PDPK1 IGF1 0 0 456 456 1 2
PDPK1 MAPK1 0 900 325 926 1 2
PDPK1 PPP2R1A 0 0 96 193 1 1
PDPK1 BTK 0 0 218 228 1 1
PDPK1 MERTK 0 0 0 163 1 1
PDPK1 NEDD4L 0 0 107 182 1 1
PDPK1 REM1 0 0 0 186 1 1
PDPK1 KAT2B 0 0 60 155 1 1
PDPK1 YWHAQ 486 0 95 580 1 1
PDPK1 ADRB2 0 0 92 183 1 1
PDPK1 RPS6KB1 475 900 755 984 1 2
PDPK1 BAD 0 650 181 701 1 2
PDPK1 PPP2CA 0 0 113 231 1 1
PDPK1 PRKDC 0 0 134 373 1 2
PDPK1 EIF4E 0 0 344 410 1 2
PDPK1 NCOR1 0 0 108 216 1 1
PDPK1 CDK1 0 0 206 231 1 2
PDPK1 NTRK1 0 0 241 241 1 1
PDPK1 CC2D1A 0 0 231 230 1 1
PDPK1 IRS1 213 0 557 817 1 2
PDPK1 SGK1 767 900 645 992 1 2
PDPK1 PIK3C2B 0 0 213 468 1 1
PDPK1 EPHB1 0 0 72 174 1 1
PDPK1 IRAK2 0 0 0 199 1 1
PDPK1 NCF1 0 0 460 460 1 1
PDPK1 ANXA2 0 0 305 305 1 1
PDPK1 SPTLC2 0 0 0 276 1 1
PDPK1 ACTN1 0 0 44 158 1 1
PDPK1 MED13L 0 0 51 170 1 1
PDPK1 ATR 0 0 49 237 1 2
PDPK1 SREBF2 0 0 96 158 1 1
PDPK1 HSF2 0 0 0 161 1 1
PDPK1 PPP1R3B 0 0 87 170 1 1
PDPK1 CCND1 0 0 341 341 1 2
PDPK1 SRPR 0 0 49 206 1 1
PDPK1 PRKAA1 0 0 181 265 1 2
PDPK1 ARHGEF7 0 0 138 156 1 1
PDPK1 DCUN1D4 0 0 0 188 1 1
PDPK1 EPHA1 0 0 54 168 1 1
PDPK1 NOS3 0 650 321 756 1 2
PDPK1 ULK3 0 0 81 190 1 2
PDPK1 ACTA2 0 0 0 169 1 1
PDPK1 RAB14 0 0 307 324 1 1
PDPK1 GNB2L1 0 0 82 294 1 1
PDPK1 PIP5KL1 0 0 0 207 1 1
PDPK1 CTLA4 0 0 176 175 1 2
PDPK1 SSH3 0 0 0 159 1 1
PDPK1 TLDC1 0 0 0 172 1 1
PDPK1 RNASEL 0 0 0 196 1 1
PDPK1 RHEB 0 0 509 740 1 2
PDPK1 DDIT4 115 0 235 362 1 2
PDPK1 PITPNA 0 0 63 162 1 1
PDPK1 FOXA2 0 0 50 271 1 1
PDPK1 PPP2R5E 0 0 96 266 1 1
PDPK1 MAP2K2 0 0 155 221 1 1
PDPK1 PHLPP2 0 0 211 411 1 1
PDPK1 BMPR2 0 0 0 170 1 1
PDPK1 CCNE1 0 0 107 153 1 1
PDPK1 ENSG00000259060 0 0 240 239 1 1
PDPK1 MCM7 0 0 60 159 1 1
PDPK1 ENSG00000258973 0 0 0 176 1 1
PDPK1 EPN3 0 0 0 183 1 1
PDPK1 HGF 0 0 157 156 1 2
PDPK1 PTK2B 213 0 702 491 1 1
PDPK1 CAT 0 0 142 226 1 2
PDPK1 MKL2 0 0 0 302 1 1
PDPK1 TSSK2 0 0 0 175 1 1
PDPK1 TESK1 0 0 0 163 1 1
PDPK1 NEK6 0 0 94 157 1 1
PDPK1 HTRA4 0 0 0 167 1 1
PDPK1 SGPP2 0 0 0 158 1 1
PDPK1 BMPR1A 0 0 0 173 1 1
PDPK1 PTEN 0 0 603 851 1 2
PDPK1 DSTYK 0 0 0 165 1 1
PDPK1 VEGFA 0 0 298 298 1 2
PDPK1 MAPK7 0 0 204 189 1 1
PDPK1 PRKAA2 0 0 127 261 1 2
PDPK1 PMEPA1 0 0 167 167 1 1
PDPK1 RRAGB 0 0 61 156 1 1
PDPK1 PI4KB 0 0 0 279 1 1
PDPK1 RPS6KL1 0 0 0 186 1 1
PDPK1 PCMT1 0 0 0 223 1 1
PDPK1 NTRK3 0 0 103 187 1 1
PDPK1 ONECUT2 0 0 54 158 1 1
PDPK1 NFE2L1 0 0 0 188 1 1
PDPK1 NFKBIA 0 650 194 712 1 2
PDPK1 LEP 0 0 219 219 1 1
PDPK1 RHOT2 0 0 74 559 1 1
PDPK1 SYK 0 0 167 211 1 2
PDPK1 ASAP2 0 0 52 169 1 1
PDPK1 MAP3K3 0 0 136 182 1 1
PDPK1 ORMDL2 0 0 0 261 1 1
PDPK1 LOC110117498-PIK3R3 0 0 0 375 1 1
PDPK1 CHD2 0 0 103 176 1 1
PDPK1 MAPK10 0 0 143 190 1 2
PDPK1 RAB27B 0 0 77 175 1 1
PDPK1 TSSK6 0 0 0 191 1 1
PDPK1 SREBF1 0 0 267 317 1 1
PDPK1 GNB4 0 650 51 653 1 1
PDPK1 CFL1 0 0 260 283 1 1
PDPK1 MAPK14 0 0 294 283 1 2
PDPK1 RORB 0 0 0 207 1 1
PDPK1 SHC1 0 650 321 767 1 1
PDPK1 CRB2 0 0 0 192 1 1
PDPK1 ATM 0 0 201 211 1 2
PDPK1 ITGA2B 0 900 66 911 1 1
PDPK1 TYRO3 0 0 0 163 1 1
PDPK1 CSRP3 0 0 46 209 1 1
PDPK1 AGRP 0 0 165 165 1 1
PDPK1 OGT 0 800 66 809 1 2
PDPK1 ELL2 0 0 42 163 1 1
PDPK1 EPHA6 0 0 0 163 1 1
PDPK1 ACTG1 0 0 95 235 1 1
PDPK1 TRAT1 0 650 0 650 1 1
PDPK1 TJP1 0 0 184 253 1 1
PDPK1 TGFBR2 0 900 90 915 1 1
PDPK1 ATG7 0 0 124 259 1 2
PDPK1 PTK7 0 0 0 164 1 1
PDPK1 MON2 0 0 0 159 1 1
PDPK1 IRAK4 0 0 95 291 1 1
PDPK1 PA2G4 169 0 0 210 1 1
PDPK1 CLIP3 0 0 81 155 1 1
PDPK1 CPT1C 0 0 142 175 1 1
PDPK1 STRAP 462 900 157 951 1 1
PDPK1 CDK7 0 0 113 154 1 1
PDPK1 MTDH 0 0 155 154 1 2
PDPK1 HSPB1 0 0 150 199 1 2
PDPK1 APBB3 170 0 0 169 1 1
PDPK1 DYRK1A 0 0 167 171 1 1
PDPK1 HSPB2 0 0 138 169 1 1
PDPK1 PACSIN3 0 0 0 157 1 1
PDPK1 NPC1L1 0 0 0 250 1 1
PDPK1 ESPN 0 0 0 150 1 1
PDPK1 TGFBR1 0 900 119 922 1 1
PDPK1 MST1R 0 0 52 167 1 1
PDPK1 NECAB3 0 0 113 206 1 1
PDPK1 EFNA2 0 0 96 158 1 1
PDPK1 SPHK1 0 0 0 162 1 2
PDPK1 ADAM17 270 0 75 344 1 1
PDPK1 MAMDC4 0 0 0 173 1 1
PDPK1 SPHK2 0 0 67 185 1 1
PDPK1 MAP1LC3B 0 0 124 155 1 2
PDPK1 PPP1R14A 0 650 74 662 1 1
PDPK1 CDC25B 0 0 89 154 1 1
PDPK1 ULK1 270 0 234 365 1 2
PDPK1 RIPK4 0 0 60 183 1 1
PDPK1 GNPTG 0 0 69 323 1 1
PDPK1 PKN3 0 800 171 876 1 1
PDPK1 PKN1 462 800 261 932 1 1
PDPK1 STK39 0 0 0 170 1 1
PDPK1 ACVRL1 0 0 44 164 1 1
PDPK1 OSBPL8 117 0 0 207 1 1
PDPK1 RPS6KA1 213 900 519 949 1 1
PDPK1 PRKCA 0 900 360 909 1 1
PDPK1 STMN1 0 0 96 150 1 1
PDPK1 NEK2 0 0 81 157 1 1
PDPK1 PIP4K2C 0 0 0 207 1 1
PDPK1 ATXN3L 0 0 0 373 1 1
PDPK1 AKT3 213 900 712 959 1 2
PDPK1 RALA 0 0 143 178 1 1
PDPK1 TBP 0 0 66 268 1 1
PDPK1 FN1 0 0 194 194 1 2
PDPK1 MUSK 0 0 0 163 1 1
PDPK1 IKBKG 0 900 123 913 1 1
PDPK1 SIRT1 0 0 206 355 1 2
PDPK1 PLIN2 0 0 181 210 1 2
PDPK1 MCL1 0 0 218 218 1 2
PDPK1 INPP4A 0 0 141 184 1 1
PDPK1 BCOR 0 0 0 177 1 1
PDPK1 PDIK1L 0 0 0 202 1 1
PDPK1 GNG8 0 650 0 650 1 1
PDPK1 LYN 0 0 439 376 1 1
PDPK1 PPP1CA 0 0 67 192 1 1
PDPK1 RAC1 0 600 120 661 1 2
PDPK1 PIM2 0 0 113 194 1 1
PDPK1 ESR1 0 0 260 260 1 2
PDPK1 MAP3K5 0 0 432 202 1 1
PDPK1 GNA11 0 0 74 150 1 1
PDPK1 BACE1 0 0 108 159 1 2
PDPK1 SMARCD2 0 0 0 193 1 1
PDPK1 PDK4 0 0 90 317 1 1
PDPK1 SMAD7 0 900 128 911 1 1
PDPK1 ITGB3 213 900 52 924 1 1
PDPK1 ENSG00000279765 0 0 103 170 1 1
PDPK1 CAMK1 0 0 69 156 1 1
PDPK1 MAP2K6 0 0 0 154 1 1
PDPK1 KSR1 0 0 47 168 1 1
PDPK1 RNF114 0 0 58 223 1 1
PDPK1 ATG5 0 0 150 238 1 2
PDPK1 TCF25 130 0 0 157 1 1
PDPK1 PPP2R2C 0 0 107 183 1 1
PDPK1 PTPN1 0 0 241 259 1 1
PDPK1 MYBL2 0 0 164 273 1 1
PDPK1 YAP1 0 0 164 222 1 2
PDPK1 FPGT-TNNI3K 0 0 0 164 1 1
PDPK1 CARD11 277 900 120 933 1 1
PDPK1 MALRD1 0 0 0 173 1 1
PDPK1 NOD1 0 0 0 262 1 2
PDPK1 PPP1R3A 0 0 58 184 1 1
PDPK1 STK17A 0 0 0 152 1 1
PDPK1 ORMDL1 0 0 0 261 1 1
PDPK1 CDC25A 0 0 99 164 1 1
PDPK1 PSMD9 0 0 0 244 1 1
PDPK1 PAK4 0 0 308 182 1 1
PDPK1 HDHD2 0 0 0 165 1 1
PDPK1 SCD5 0 0 73 232 1 1
PDPK1 DNAH17 0 0 73 150 1 1
PDPK1 CD86 0 650 53 654 1 1
PDPK1 RRAGD 0 0 124 171 1 1
PDPK1 MET 0 0 173 214 1 2
PDPK1 SGPP1 0 0 0 158 1 1
PDPK1 ATXN3 42 0 81 399 1 2
PDPK1 LRRK2 0 0 64 288 1 2
PDPK1 PIK3CB 0 800 469 943 1 1
PDPK1 PRKCH 0 0 57 390 1 1
PDPK1 PIM3 0 0 90 193 1 1
PDPK1 MAPK11 0 0 118 238 1 1
PDPK1 PEA15 74 0 60 205 1 1
PDPK1 EIF4EBP2 0 0 108 463 1 1
PDPK1 SNX4 0 0 49 173 1 2
PDPK1 STXBP1 0 0 0 170 1 1
PDPK1 FAM213B 74 0 0 213 1 1
PDPK1 SMARCD3 0 0 0 318 1 1
PDPK1 CAMK2B 0 0 413 180 1 1
PDPK1 BECN1 0 0 166 236 1 2
PDPK1 CDK9 0 0 134 159 1 1
PDPK1 THEM4 0 650 385 775 1 1
PDPK1 GNB3 0 650 0 650 1 1
PDPK1 TSSK4 0 0 0 175 1 1
PDPK1 SOD2 0 0 56 156 1 2
PDPK1 FOXO1 0 0 517 545 1 2
PDPK1 TPTE2 0 0 53 242 1 1
PDPK1 KRAS 0 600 371 763 1 2
PDPK1 SH2B1 0 0 73 232 1 1
PDPK1 DUSP3 0 0 97 150 1 1
PDPK1 PKN2 932 800 949 993 1 1
PDPK1 CAMK4 0 0 112 180 1 1
PDPK1 EIF4A2 0 0 108 187 1 1
PDPK1 FKBP10 0 0 0 152 1 1
PDPK1 MLST8 0 0 455 681 1 1
PDPK1 MTPN 0 0 103 354 1 1
PDPK1 HAX1 0 0 54 165 1 1
PDPK1 HSPA5 117 0 134 243 1 2
PDPK1 ZNRF3 0 0 45 165 1 1
PDPK1 NRAS 0 600 140 676 1 1
PDPK1 IRAK3 0 0 0 199 1 1
PDPK1 PTPN11 0 0 207 230 1 1
PDPK1 DEPTOR 0 0 335 335 1 2
PDPK1 RRAGC 0 0 144 190 1 1
PDPK1 ASB5 0 0 95 164 1 1
PDPK1 RXRA 0 0 135 158 1 1
PDPK1 STAT5A 0 0 143 250 1 1
PDPK1 GNG5 0 650 0 654 1 1
PDPK1 ANGPTL4 0 0 217 265 1 1
PDPK1 MATK 0 0 45 164 1 1
PDPK1 PNPLA7 0 0 0 156 1 1
PDPK1 PRKAR1A 0 0 150 353 1 2
PDPK1 PTK6 0 0 144 260 1 2
PDPK1 ENSG00000263620 0 0 0 276 1 1
PDPK1 GNGT2 0 650 0 650 1 1
PDPK1 SOCS3 67 0 155 195 1 1
PDPK1 DDX24 117 0 0 156 1 1
PDPK1 YWHAZ 128 0 294 447 1 1
PDPK1 FASLG 0 0 419 419 1 1
PDPK1 TEX43 0 0 195 195 1 1
PDPK1 FOS 0 0 181 181 1 2
PDPK1 BIN3 0 0 0 161 1 1
PDPK1 MAP3K10 0 0 0 169 1 1
PDPK1 RIPK1 0 0 140 200 1 2
PDPK1 YWHAH 415 0 118 518 1 1
PDPK1 TXNRD1 0 0 123 187 1 1
PDPK1 TBC1D7 0 0 210 220 1 2
PDPK1 RASA2 0 0 0 278 1 1
PDPK1 MEF2A 0 0 103 204 1 1
PDPK1 INPP4B 0 0 218 222 1 1
PDPK1 PIK3CD 0 800 364 932 1 1
PDPK1 HCK 0 0 51 232 1 1
PDPK1 STK24 0 0 46 162 1 1
PDPK1 SORBS2 0 0 75 174 1 1
PDPK1 PI4KA 0 0 0 237 1 1
PDPK1 EPHB2 0 0 54 168 1 2
PDPK1 CHUK 0 900 180 918 1 1
PDPK1 PDE3B 0 0 173 191 1 1
PDPK1 INSRR 0 0 161 342 1 1
PDPK1 PFDN6 0 0 61 152 1 1
PDPK1 GNG3 0 650 0 650 1 1
PDPK1 BLK 0 0 67 173 1 1
PDPK1 GSK3B 0 650 412 771 1 2
PDPK1 PTPN12 129 0 53 161 1 1
PDPK1 CDKN2A 0 0 181 198 1 2
PDPK1 PPP6C 0 0 82 286 1 1
PDPK1 BMPR1B 0 0 0 173 1 1
PDPK1 FABP4 0 0 115 152 1 1
PDPK1 EPHA3 0 0 74 175 1 1
PDPK1 SFN 131 0 0 205 1 2
PDPK1 ENTHD1 0 0 0 171 1 1
PDPK1 ENSG00000268643 0 0 0 248 1 1
PDPK1 MAPK15 0 0 146 164 1 1
PDPK1 CD28 0 650 155 691 1 1
PDPK1 GNG10 0 650 73 661 1 1
PDPK1 ATG12 0 0 107 245 1 2
PDPK1 STK17B 0 0 81 191 1 1
PDPK1 PRKCQ 270 900 290 953 1 2
PDPK1 FAM168A 0 0 203 234 1 1
PDPK1 EPHA5 0 0 100 185 1 1
PDPK1 PTGS2 0 0 249 248 1 2
PDPK1 DDX6 0 0 0 270 1 1
PDPK1 CASP3 0 0 315 349 1 2
PDPK1 EIF4B 0 0 255 386 1 1
PDPK1 LIMK1 0 0 92 209 1 1
PDPK1 LTK 0 0 0 173 1 1
PDPK1 TNNI3K 0 0 0 164 1 1
PDPK1 RPS6KC1 0 0 0 205 1 1
PDPK1 HSPB8 0 0 63 305 1 2
PDPK1 HYPK 0 0 73 259 1 1
PDPK1 UBE2V1 0 900 48 900 1 1
PDPK1 PLD2 0 0 74 205 1 1
PDPK1 TRIB3 0 650 70 683 1 2
PDPK1 ATXN1 0 0 99 183 1 1
PDPK1 ASAP1 0 0 0 159 1 1
PDPK1 UBE2G1 0 0 49 153 1 1
PDPK1 ACVR1C 0 0 0 186 1 1
PDPK1 NDRG1 0 0 161 161 1 1
PDPK1 MAPK13 0 0 66 211 1 1
PDPK1 KIAA1429 270 0 0 273 1 1
PDPK1 IL1B 0 0 161 161 1 2
PDPK1 MAPKAPK5 0 0 108 150 1 1
PDPK1 SP1 0 0 90 153 1 2
PDPK1 PKD1L1 0 0 0 260 1 1
PDPK1 GCK 0 0 242 241 1 1
PDPK1 NEDD4 0 0 93 156 1 2
PDPK1 SIRT5 0 0 108 228 1 1
PDPK1 HIF1A 0 0 354 420 1 2
PDPK1 PRKCB 270 900 252 929 1 2
PDPK1 XPO1 0 0 49 173 1 1
PDPK1 INPP5B 0 0 74 185 1 1
PDPK1 PRKAG1 0 0 103 153 1 1
PDPK1 IKBKE 0 0 134 199 1 1
PDPK1 PRKAR2B 0 0 66 291 1 1
PDPK1 ENSG00000270249 0 0 0 189 1 1
PDPK1 ATE1 0 0 61 282 1 1
PDPK1 SH2B2 0 0 0 205 1 1
PDPK1 PASK 0 0 0 224 1 1
PDPK1 PLA2G4A 0 0 357 371 1 1
PDPK1 BAZ1A 0 0 0 162 1 1
PDPK1 DCAF6 0 0 48 164 1 1
PDPK1 EPHA2 0 0 103 186 1 1
PDPK1 APP 0 0 113 150 1 2
PDPK1 CDK2 0 0 294 261 1 2
PDPK1 HRAS 0 600 395 771 1 2
PDPK1 C7 0 0 58 152 1 1
PDPK1 ENSG00000258989 0 0 0 363 1 1
PDPK1 CTNNB1 0 0 296 348 1 2
PDPK1 POTEF 0 0 98 211 1 1
PDPK1 MTOR 191 0 611 842 1 2
PDPK1 MAPKAP1 0 0 357 633 1 1
PDPK1 FKBP15 0 0 0 162 1 1
PDPK1 ARAF 0 0 178 273 1 1
PDPK1 MAST1 0 0 0 169 1 1
PDPK1 NOTCH1 0 0 181 218 1 2
PDPK1 UBE2A 0 0 49 152 1 1
PDPK1 PLEK 0 0 635 635 1 1
PDPK1 TBC1D16 0 0 113 168 1 1
PDPK1 RPS6 0 0 450 654 1 2
PDPK1 SBK1 0 0 101 255 1 1
PDPK1 SOCS5 0 0 171 189 1 1
PDPK1 FOXO6 0 0 203 233 1 1
PDPK1 STAT1 0 0 108 169 1 2
PDPK1 IL6 0 0 215 215 1 2
PDPK1 DCXR 0 0 54 198 1 1
PDPK1 DCAF8L2 0 0 0 192 1 1
PDPK1 PRKG1 0 0 389 185 1 1
PDPK1 PIK3C3 0 0 232 398 1 2
PDPK1 NLRC3 0 0 66 318 1 1
PDPK1 MAP3K2 0 0 61 159 1 1
PDPK1 PPP1R12A 0 0 108 161 1 1
PDPK1 CREB1 0 0 267 303 1 2
PDPK1 TGFB3 0 900 0 901 1 1
PDPK1 DCUN1D5 0 0 98 312 1 1
PDPK1 PLCG2 0 0 95 151 1 1
PDPK1 P3R3URF 0 0 0 326 1 1
PDPK1 DHX9 117 0 0 150 1 1
PDPK1 BIRC2 0 0 67 167 1 1
PDPK1 PNPO 0 0 60 166 1 1
PDPK1 STAM2 0 0 56 166 1 1
PDPK1 PRKACA 270 0 57 424 1 1
PDPK1 GRB10 0 0 167 173 1 1
PDPK1 TENC1 0 0 60 320 1 1
PDPK1 USP43 0 0 74 232 1 1
PDPK1 HSF1 0 0 0 209 1 2
PDPK1 ENSG00000258472 0 0 0 342 1 1
PDPK1 SCAP 0 0 90 238 1 1
PDPK1 AMOTL1 0 0 305 305 1 1
PDPK1 CAMSAP3 190 0 0 190 1 1
PDPK1 POLR2A 117 0 66 228 1 1
PDPK1 FOXM1 0 0 122 155 1 1
PDPK1 FLNC 117 0 0 175 1 1
PDPK1 ZDHHC17 270 0 0 270 1 1
PDPK1 INPPL1 0 0 202 279 1 1
PDPK1 CCNB1 0 0 171 183 1 1
PDPK1 ANXA5 0 0 183 183 1 2
PDPK1 RORA 0 0 0 207 1 1
PDPK1 BCL2L1 270 0 284 454 1 2
PDPK1 RELA 0 650 107 676 1 2
PDPK1 TEC 0 0 139 199 1 1
PDPK1 DNMT3B 0 0 53 220 1 1
PDPK1 DNMT3A 0 0 63 176 1 2
PDPK1 NFKB1 0 650 125 702 1 2
PDPK1 EPHA8 0 0 0 163 1 1
PDPK1 PHLPP1 0 0 342 500 1 2
PDPK1 STAT4 0 0 43 159 1 1
PDPK1 ZAP70 0 0 91 182 1 1
PDPK1 PIK3R4 0 0 124 190 1 2
PDPK1 HEBP2 0 0 75 170 1 1
PDPK1 TSSK3 0 0 0 178 1 1
PDPK1 MAP2K7 0 0 412 192 1 1
PDPK1 CPA4 273 0 76 299 1 1
PDPK1 NF1 0 0 138 161 1 1
PDPK1 ABL1 0 0 248 263 1 1
PDPK1 GABARAPL2 0 0 126 200 1 2
PDPK1 FKBP8 0 0 174 241 1 1
PDPK1 APOA1 0 0 94 223 1 1
PDPK1 PRR5 0 0 310 385 1 1
PDPK1 RPS6KA5 0 0 214 298 1 1
PDPK1 POTEE 0 0 0 162 1 1
PDPK1 SMG1 0 0 57 345 1 1
PDPK1 GAPDH 0 0 282 313 1 2
PDPK1 LARS2 0 0 56 161 1 1
PDPK1 RIOK2 0 0 0 163 1 1
PDPK1 SMAD2 0 0 144 167 1 2
PDPK1 CDK10 0 0 0 172 1 1
PDPK1 KSR2 0 0 0 165 1 1
PDPK1 ARHGAP12 0 0 68 237 1 1
PDPK1 TLR4 0 0 120 165 1 2
PDPK1 SRMS 0 0 0 163 1 1
PDPK1 PI3 0 0 231 236 1 2
PDPK1 RASAL1 0 0 0 189 1 1
PDPK1 PPARGC1A 0 0 193 193 1 2
PDPK1 IGF1R 0 0 391 396 1 2
PDPK1 TAB2 0 600 0 609 1 2
PDPK1 GRB14 0 900 0 900 1 1
PDPK1 ILK 270 0 458 656 1 1
PDPK1 RALGDS 213 900 202 931 1 1
PDPK1 PDK1 0 0 146 359 1 2
PDPK1 MYC 0 0 341 349 1 2
PDPK1 MATN2 0 0 55 154 1 1
PDPK1 CBLB 270 0 0 286 1 1
PDPK1 STK32B 0 0 60 453 1 1
PDPK1 POLR2G 0 0 52 197 1 1
PDPK1 PPP5C 0 0 134 184 1 1
PDPK1 ACACA 0 0 150 169 1 1
PDPK1 ROR1 0 0 48 166 1 1
PDPK1 INPP5F 0 0 166 212 1 1
PDPK1 PIK3CA 0 900 556 977 1 2
PDPK1 MED30 0 0 69 240 1 1
PDPK1 TPI1 0 0 42 209 1 1
PDPK1 GAB2 0 650 67 659 1 1
PDPK1 PIK3R3 0 800 297 904 1 1
PDPK1 NPC1 0 0 0 250 1 2
PDPK1 GNAQ 0 0 108 182 1 1
PDPK1 ARHGEF28 0 0 0 150 1 1
PDPK1 USP15 0 0 0 216 1 1
PDPK1 SLC7A1 0 0 48 167 1 1
PDPK1 RICTOR 0 0 637 852 1 2
PDPK1 APPL1 0 0 70 195 1 1
PDPK1 FKBP1B 0 0 0 175 1 1
PDPK1 G6PC 0 0 262 262 1 1
PDPK1 MED21 0 0 69 168 1 1
PDPK1 MYLK4 0 0 0 160 1 1
PDPK1 ACTA1 0 0 72 188 1 1
PDPK1 ANAPC11 0 0 49 171 1 1
PDPK1 NGDN 0 0 181 206 1 1
PDPK1 FXN 0 0 217 367 1 1
PDPK1 GNG11 0 650 0 650 1 1
PDPK1 PARD3 0 0 269 395 1 1
PDPK1 PBK 0 0 66 198 1 1
PDPK1 HTRA3 0 0 0 167 1 1
PDPK1 SLC2A3 0 0 112 161 1 1
PDPK1 MEF2D 0 0 67 164 1 2
PDPK1 SMAD4 0 0 181 381 1 2
PDPK1 FLNA 0 0 73 169 1 1
PDPK1 MAP3K8 0 650 96 700 1 1
PDPK1 TOP2A 0 0 57 151 1 1
PDPK1 MAP2K1 0 0 404 283 1 1
PDPK1 BOLA2 0 0 0 324 1 1
PDPK1 SYNJ1 0 0 62 223 1 1
PDPK1 PIP4K2A 0 0 133 283 1 1
PDPK1 STK11 0 0 310 208 1 2
PDPK1 CD80 0 650 49 652 1 2
PDPK1 BRCA1 0 0 155 154 1 2
PDPK1 PLEKHA5 0 0 92 180 1 1
PDPK1 ENSG00000272772 0 0 0 162 1 1
PDPK1 GNG12 0 650 0 650 1 1
PDPK1 ACER3 0 0 57 159 1 1
PDPK1 GNG4 0 650 0 650 1 1
PDPK1 AKT2 462 900 596 971 1 2
PDPK1 LARP1 0 0 108 195 1 1
PDPK1 POLR2F 0 0 73 229 1 1
PDPK1 MAP2K5 0 0 143 222 1 1
PDPK1 RB1CC1 0 0 134 212 1 2
PDPK1 FES 0 0 53 179 1 1
PDPK1 EGFR 0 0 415 247 1 2
PDPK1 CDK4 0 0 233 262 1 2
PDPK1 AMHR2 0 0 0 170 1 1
PDPK1 SLC2A1 0 0 282 321 1 2
PDPK1 DCUN1D1 0 0 0 173 1 1
PDPK1 PRKCE 462 900 127 964 1 1
PDPK1 ATP6V0C 0 0 92 177 1 1
PDPK1 CKS1B 0 0 60 158 1 1
PDPK1 PRKCI 408 900 233 951 1 1
PDPK1 MDM2 0 650 309 753 1 2
PDPK1 TP53 0 0 391 390 1 2
PDPK1 CDC42BPG 0 0 0 168 1 1
PDPK1 PRKX 0 0 212 260 1 1
PDPK1 ARF5 0 0 49 244 1 1
PDPK1 PRKACG 0 0 0 249 1 1
PDPK1 TNS3 0 0 0 307 1 1
PDPK1 PPP2R5D 0 0 74 236 1 1
PDPK1 MED13 0 0 0 159 1 1
PDPK1 MAP3K7 270 600 112 743 1 2
PDPK1 HDAC2 0 0 293 293 1 1
PDPK1 NME3 0 0 88 150 1 1
PDPK1 HK2 0 0 236 236 1 2
PDPK1 SLC9A3R2 270 0 444 580 1 1
PDPK1 RAF1 0 0 322 304 1 2
PDPK1 SERPINA4 342 0 95 417 1 1
PDPK1 TXK 0 0 147 202 1 1
PDPK1 IRAK1 0 0 92 194 1 1
PDPK1 NCOR2 0 0 66 182 1 1
PDPK1 PPARD 0 0 140 268 1 1
PDPK1 OXSR1 0 0 0 189 1 1
PDPK1 HGS 0 0 57 158 1 2
PDPK1 NPRL2 0 0 472 477 1 1
PDPK1 AAED1 0 0 0 157 1 1
PDPK1 PDXP 0 0 0 190 1 1
PDPK1 FGR 0 0 51 167 1 1
PDPK1 SHC3 0 0 184 235 1 1
PDPK1 CDH2 0 0 161 310 1 1
PDPK1 PAK1 213 0 195 383 1 2
PDPK1 JAK2 0 0 217 228 1 2
PDPK1 HTRA1 0 0 0 167 1 1
PDPK1 KIAA0907 0 0 134 237 1 1
PDPK1 EZH2 0 0 103 189 1 2
PDPK1 GDNF 0 0 113 155 1 2
PDPK1 STAT3 0 0 320 337 1 2
PDPK1 AGO2 0 0 100 158 1 2
PDPK1 EIF2AK4 0 0 133 265 1 2
PDPK1 CECR5 0 0 0 198 1 1
PDPK1 WDR42A 0 0 88 231 1 1
PDPK1 PRKAR2A 0 0 213 403 1 1
PDPK1 NF2 0 0 88 155 1 1
PDPK1 OCRL 0 0 0 352 1 1
PDPK1 GNGT1 0 650 0 650 1 1
PDPK1 SPTLC1 0 0 0 556 1 1
PDPK1 ERN1 0 0 102 186 1 2
PDPK1 CSNK1D 117 0 45 151 1 1
PDPK1 CASP7 0 0 142 210 1 1
PDPK1 GNB5 0 650 0 650 1 1
PDPK1 ITGB1 0 0 108 182 1 1
PDPK1 CRABP2 0 0 218 231 1 1
PDPK1 CASP8 0 0 166 198 1 2
PDPK1 SGK2 213 800 193 943 1 1
PDPK1 ALB 0 0 229 240 1 2
PDPK1 RC3H1 0 0 0 161 1 1
PDPK1 CDC37 178 0 0 183 1 1
PDPK1 GNB2 0 650 55 655 1 1
PDPK1 PPP2R1B 0 0 142 265 1 1
PDPK1 EIF4A1 0 0 123 211 1 1
PDPK1 SLC25A37 0 0 96 158 1 1
PDPK1 VAMP2 0 0 82 307 1 1
PDPK1 ROCK1 0 0 458 300 1 2
PDPK1 PKNOX1 0 0 73 205 1 1
PDPK1 MYLK 0 0 310 174 1 1
PDPK1 PIP5K1C 0 0 163 334 1 1
PDPK1 BIRC3 0 0 84 184 1 1
PDPK1 FAM213A 0 0 0 157 1 1
PDPK1 SMAD3 0 0 140 163 1 2
PDPK1 CSNK2A2 0 0 193 238 1 1
PDPK1 SH3PXD2B 0 0 0 252 1 1
PDPK1 MRPL10 0 0 0 256 1 1
PDPK1 TPTE 0 0 0 233 1 1
PDPK1 IL4 0 0 107 173 1 1
PDPK1 ENSG00000267318 0 0 0 558 1 1
PDPK1 CDK5 0 0 170 173 1 2
PDPK1 EP300 0 0 150 220 1 2
PDPK1 PRKCZ 766 900 404 981 1 1
PDPK1 SH3PXD2A 0 0 0 252 1 1
PDPK1 CDH1 0 0 213 213 1 2
PDPK1 SNX15 0 0 0 216 1 1
PDPK1 VPS35 0 0 44 215 1 2
PDPK1 CDK16 0 0 66 208 1 1
PDPK1 FRK 0 0 123 282 1 1
PDPK1 ADAP1 0 0 123 164 1 1
PDPK1 CDK6 0 0 184 237 1 2
PDPK1 SGK494 0 0 0 353 1 1
PDPK1 ACTC1 0 0 0 190 1 1
PDPK1 MAPKAPK2 0 0 193 179 1 1
PDPK1 MAP3K9 0 0 0 169 1 1
PDPK1 AKTIP 213 0 645 708 1 1
PDPK1 EPHA4 0 0 0 163 1 1
PDPK1 YWHAG 131 0 56 234 1 1
PDPK1 SUZ12 0 0 0 173 1 1
PDPK1 ROCK2 117 0 280 316 1 1
PDPK1 PPP1CB 0 0 63 169 1 1
PDPK1 ALK 0 0 155 271 1 2
PDPK1 ACVR2B 0 0 0 193 1 1
PDPK1 LBX1 0 0 63 158 1 1
PDPK1 RHOB 0 600 112 709 1 1
PDPK1 STK32A 0 0 0 487 1 1
PDPK1 BOLA2B 0 0 0 306 1 1
PDPK1 PPP2R5A 0 0 0 186 1 1
PDPK1 PFDN5 0 0 0 168 1 1
PDPK1 MAP3K11 0 0 140 230 1 1
PDPK1 PIK3R5 0 800 292 852 1 1
PDPK1 ABL2 0 0 119 219 1 1
PDPK1 CPT1B 0 0 137 200 1 1
PDPK1 FKBP1A 0 0 250 354 1 2
PDPK1 NR3C1 0 0 196 196 1 1
PDPK1 DAPK3 0 0 0 158 1 2
PDPK1 SRPK1 289 0 0 320 1 1
PDPK1 TEX13A 0 0 0 165 1 1
PDPK1 RASA4 0 0 0 189 1 1
PDPK1 CSK 170 0 90 377 1 1
PDPK1 PPP2R5B 0 0 0 179 1 1
PDPK1 RPS6KB2 213 800 231 945 1 2
PDPK1 SESN2 0 0 140 161 1 2
PDPK1 PXN 213 0 143 357 1 1
PDPK1 HSPA6 129 0 0 184 1 1
PDPK1 PAK3 0 0 75 235 1 1
PDPK1 ACAP3 0 0 0 208 1 1
PDPK1 TNS1 0 0 369 544 1 1
PDPK1 PAK2 0 0 45 235 1 1
PDPK1 MAP2K4 0 0 86 166 1 1
PDPK1 PLD1 0 0 148 268 1 2
PDPK1 PKDCC 0 0 0 199 1 1
PDPK1 BRAF 0 0 157 241 1 2
PDPK1 PRKAR1B 0 0 104 318 1 1
PDPK1 MUT 0 0 113 341 1 1
PDPK1 BCKDK 0 0 0 246 1 1
PDPK1 MAPK8 270 0 231 406 1 2
PDPK1 NSMAF 0 0 82 159 1 1
PDPK1 PRKAB1 0 0 171 260 1 2
PDPK1 EIF2S2 0 0 0 200 1 1
PDPK1 ADIPOQ 0 0 150 173 1 2
PDPK1 ACAP2 0 0 64 222 1 1
PDPK1 SOS2 0 0 143 215 1 1
PDPK1 FASN 0 0 157 162 1 2
PDPK1 SETD7 0 0 0 205 1 1
PDPK1 EGF 0 0 321 321 1 2
PDPK1 PRKAB2 0 0 82 176 1 1
PDPK1 RPS6KA3 632 900 517 976 1 1
PDPK1 CYCS 0 0 172 171 1 2
PDPK1 MAPK9 0 0 166 207 1 2
PDPK1 APPL2 0 0 0 170 1 1
PDPK1 PDP1 0 0 123 195 1 1
PDPK1 CASP9 0 650 309 757 1 2
PDPK1 TBC1D15 117 0 0 172 1 1
PDPK1 MTM1 0 0 95 250 1 2
PDPK1 RPS6KA4 0 0 58 264 1 1
PDPK1 POMC 0 0 161 161 1 1
PDPK1 PRRT2 0 0 326 325 1 1
PDPK1 TRAF6 0 900 150 911 1 2
PDPK1 PPARA 0 0 251 264 1 2
PDPK1 FAM199X 879 0 0 879 1 1
PDPK1 HSP90B1 0 0 95 167 1 1
PDPK1 RPTOR 0 0 469 673 1 2
PDPK1 XPO5 0 0 53 234 1 1
PDPK1 HSPB3 0 0 134 165 1 1
PDPK1 PDCD4 0 0 123 186 1 2
PDPK1 VAMP1 0 0 0 204 1 1
PDPK1 PIK3R1 0 900 459 963 1 1
PDPK1 DICER1 0 0 112 180 1 1
PDPK1 POTEJ 0 0 0 162 1 1
PDPK1 ACVR1 0 0 89 191 1 1
PDPK1 HSPA4 117 0 134 227 1 1
PDPK1 GATA4 0 0 294 299 1 2
PDPK1 TYK2 0 0 56 169 1 1
PDPK1 ACAD11 0 0 135 221 1 1
PDPK1 JUN 0 0 294 365 1 2
PDPK1 RHOT1 0 0 0 362 1 1
PDPK1 PLCG1 0 0 472 508 1 1
PDPK1 LHPP 0 0 0 165 1 1
PDPK1 WDR31 0 0 0 207 1 1
PDPK1 MAPK12 0 0 154 233 1 1
PDPK1 PARD3B 0 0 0 294 1 1
PDPK1 WDR5 487 0 0 507 1 1
PDPK1 BCL2L11 0 0 262 262 1 2
PDPK1 RC3H2 0 0 0 162 1 1
PDPK1 TSC1 0 0 321 582 1 2
PDPK1 DAPP1 0 0 142 163 1 1
PDPK1 ULK2 0 0 232 194 1 2
PDPK1 JAK3 0 0 117 191 1 1
PDPK1 APPBP2 0 0 71 182 1 1
PDPK1 PIK3CG 0 800 451 939 1 1
PDPK1 MAP2K3 0 0 120 185 1 1
PDPK1 ENSG00000268434 0 0 0 183 1 1
PDPK1 SPTLC3 0 0 0 276 1 1
PDPK1 CAV1 0 0 170 169 1 2
PDPK1 EPN1 0 0 0 229 1 1
PDPK1 MST4 0 0 0 165 1 1
PDPK1 ORMDL3 0 0 0 261 1 2
PDPK1 HSPA1A 129 0 74 223 1 1
PDPK1 ICAM5 0 0 60 158 1 1
PDPK1 AKT1S1 0 650 491 819 1 1
PDPK1 SCO1 0 0 388 388 1 1
PDPK1 CCNA2 0 0 150 163 1 1
PDPK1 RASA4B 0 0 0 189 1 1
PDPK1 EIF2AK1 0 0 0 189 1 1
PDPK1 HCFC1R1 0 0 161 218 1 1
PDPK1 ECT2L 0 0 0 157 1 1
PDPK1 NEK3 0 0 150 164 1 1
PDPK1 ENSG00000270024 0 0 520 697 1 1
PDPK1 PRKACB 0 0 134 264 1 1
PDPK1 LIMK2 0 0 60 180 1 1
PDPK1 RIPK2 0 900 73 922 1 2
PDPK1 IRS2 0 0 426 658 1 1
PDPK1 FER 0 0 0 174 1 1
PDPK1 DLL1 0 0 74 155 1 1
PDPK1 CAMK1D 0 0 82 163 1 1
PDPK1 ERN2 0 0 0 163 1 1
PDPK1 EPN2 0 0 62 208 1 1
PDPK1 CSNK1A1 0 0 112 197 1 1
PDPK1 GTPBP4 0 0 123 214 1 1
PDPK1 SOD1 0 0 73 161 1 2
PDPK1 FKBP3 0 0 0 193 1 1
PDPK1 TBC1D4 0 0 297 320 1 1
PDPK1 CDC25C 0 650 52 670 1 2
PDPK1 TTC3 0 0 47 157 1 1
PDPK1 LCK 0 650 209 719 1 1
PDPK1 YWHAE 130 0 67 280 1 1
PDPK1 PIP5K1A 0 0 134 311 1 1
PDPK1 ZAK 0 0 0 164 1 1
PDPK1 ACAP1 0 0 0 208 1 1
PDPK1 GRB2 0 650 385 792 1 1
PDPK1 FYN 0 650 204 751 1 1
PDPK1 FOXA3 0 0 0 202 1 1
PDPK1 MPC1 0 0 53 183 1 1
PDPK1 ASAP3 0 0 0 159 1 1
PDPK1 GNB1 0 650 71 660 1 1
PDPK1 PDK2 0 0 529 646 1 1
PDPK1 GABARAPL1 0 0 113 156 1 2
PDPK1 PIP5K1B 0 0 0 237 1 1
PDPK1 MLKL 0 0 0 192 1 2
PDPK1 BCL10 0 900 125 910 1 1
PDPK1 STK4 0 0 0 247 1 1
PDPK1 RHOG 0 650 0 663 1 1
PDPK1 NIM1K 0 0 0 202 1 1
PDPK1 EHHADH 0 0 74 217 1 1
PDPK1 PTPRC 129 0 104 204 1 1
PDPK1 GNG7 0 650 0 650 1 1
PDPK1 FABP5 0 0 219 225 1 1
PDPK1 AURKA 0 0 427 191 1 2
PDPK1 UBE2N 0 900 0 902 1 1
PDPK1 ECT2 0 0 74 180 1 1
PDPK1 PEX7 0 0 47 164 1 1
PDPK1 CDKN1A 0 650 241 722 1 2
PDPK1 RHOA 0 600 180 731 1 2
PDPK1 EIF4G1 0 0 177 215 1 2
PDPK1 CRTC2 0 0 180 179 1 1
PDPK1 HSPA8 274 0 66 347 1 2
PDPK1 INSR 0 900 367 936 1 1
PDPK1 MAPK3 0 0 370 314 1 2
PDPK1 ROS1 0 0 0 163 1 1
PDPK1 MMP9 0 0 149 169 1 2
PDPK1 SQSTM1 130 0 125 206 1 2
PDPK1 BNIP3 0 0 125 167 1 2
PDPK1 PCK2 0 0 193 212 1 1
PDPK1 CIT 0 0 47 173 1 1
PDPK1 EPHA10 0 0 0 163 1 1
PDPK1 FOXG1 0 0 0 227 1 1
PDPK1 CERKL 0 0 0 162 1 1
PDPK1 ACTB 0 0 304 391 1 2
PDPK1 INS 0 900 560 954 1 2
PDPK1 ATG13 0 0 183 250 1 2
PDPK1 RPS6KA6 0 900 145 930 1 1
PDPK1 NLRX1 0 0 0 268 1 2
PDPK1 HTRA2 0 0 54 179 1 1
PDPK1 EPHA7 0 0 57 169 1 1
PDPK1 HSP90AA1 213 900 766 981 1 2
PDPK1 TBL2 486 0 0 507 1 1
PDPK1 SBF1 74 0 182 361 1 1
PDPK1 GNG2 0 650 47 652 1 1
PDPK1 HADHA 117 0 0 157 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0004676 Molecular Function 3-phosphoinositide-dependent protein kinase activity enables IDA
GO:0005524 Molecular Function ATP binding enables IEA
GO:0016004 Molecular Function phospholipase activator activity enables IMP
GO:0043274 Molecular Function phospholipase binding enables IPI
GO:0005515 Molecular Function protein binding enables IPI
GO:0106310 Molecular Function protein serine kinase activity enables IEA
GO:0004674 Molecular Function protein serine/threonine kinase activity enables IBA
GO:0004674 Molecular Function protein serine/threonine kinase activity enables IDA
GO:0004674 Molecular Function protein serine/threonine kinase activity enables TAS
GO:0031295 Biological Process T cell costimulation involved_in TAS
GO:0030036 Biological Process actin cytoskeleton organization involved_in TAS
GO:0032148 Biological Process activation of protein kinase B activity involved_in IDA
GO:0019722 Biological Process calcium-mediated signaling involved_in IMP
GO:0016477 Biological Process cell migration involved_in IMP
GO:0071364 Biological Process cellular response to epidermal growth factor stimulus involved_in IMP
GO:0032869 Biological Process cellular response to insulin stimulus involved_in IMP
GO:0007173 Biological Process epidermal growth factor receptor signaling pathway involved_in IMP
GO:0097191 Biological Process extrinsic apoptotic signaling pathway involved_in IMP
GO:0006972 Biological Process hyperosmotic response involved_in IEA
GO:0008286 Biological Process insulin receptor signaling pathway involved_in IEA
GO:0048009 Biological Process insulin-like growth factor receptor signaling pathway involved_in IEA
GO:0035556 Biological Process intracellular signal transduction involved_in IBA
GO:0035556 Biological Process intracellular signal transduction acts_upstream_of_or_within IDA
GO:0010667 Biological Process negative regulation of cardiac muscle cell apoptotic process involved_in IEA
GO:2000352 Biological Process negative regulation of endothelial cell apoptotic process involved_in IMP
GO:0006469 Biological Process negative regulation of protein kinase activity involved_in IDA
GO:0034122 Biological Process negative regulation of toll-like receptor signaling pathway involved_in IEA
GO:0030512 Biological Process negative regulation of transforming growth factor beta receptor signaling pathway involved_in IDA
GO:0018105 Biological Process peptidyl-serine phosphorylation involved_in IBA
GO:0018107 Biological Process peptidyl-threonine phosphorylation involved_in IDA
GO:0016310 Biological Process phosphorylation involved_in IEA
GO:0045766 Biological Process positive regulation of angiogenesis involved_in IMP
GO:0043536 Biological Process positive regulation of blood vessel endothelial cell migration involved_in IMP
GO:0051897 Biological Process positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction involved_in TAS
GO:0010518 Biological Process positive regulation of phospholipase activity involved_in IMP
GO:1903078 Biological Process positive regulation of protein localization to plasma membrane involved_in IMP
GO:0051281 Biological Process positive regulation of release of sequestered calcium ion into cytosol involved_in IDA
GO:1903672 Biological Process positive regulation of sprouting angiogenesis involved_in IMP
GO:1905564 Biological Process positive regulation of vascular endothelial cell proliferation involved_in IMP
GO:0046777 Biological Process protein autophosphorylation involved_in TAS
GO:0006468 Biological Process protein phosphorylation involved_in IDA
GO:0043122 Biological Process regulation of canonical NF-kappaB signal transduction involved_in IMP
GO:0043304 Biological Process regulation of mast cell degranulation involved_in IEA
GO:0003323 Biological Process type B pancreatic cell development involved_in IEA
GO:0042995 Cellular Component cell projection located_in IDA
GO:0005737 Cellular Component cytoplasm located_in IDA
GO:0005737 Cellular Component cytoplasm located_in IEA
GO:0031410 Cellular Component cytoplasmic vesicle located_in IEA
GO:0005829 Cellular Component cytosol located_in IDA
GO:0005829 Cellular Component cytosol located_in TAS
GO:0005925 Cellular Component focal adhesion located_in IEA
GO:0016020 Cellular Component membrane located_in IEA
GO:0005634 Cellular Component nucleus located_in IEA
GO:0005886 Cellular Component plasma membrane located_in IDA
GO:0005886 Cellular Component plasma membrane located_in TAS
GO:0014069 Cellular Component postsynaptic density located_in IEA
Pathways
Name DB ID
Hemostasis Reactome R-HSA-109582
PI3K Cascade Reactome R-HSA-109704
Neurotransmitter receptors and postsynaptic signal transmission Reactome R-HSA-112314
Transmission across Chemical Synapses Reactome R-HSA-112315
Neuronal System Reactome R-HSA-112316
IRS-mediated signalling Reactome R-HSA-112399
GPVI-mediated activation cascade Reactome R-HSA-114604
PIP3 activates AKT signaling Reactome R-HSA-1257604
Adaptive Immune System Reactome R-HSA-1280218
Signal Transduction Reactome R-HSA-162582
Disease Reactome R-HSA-1643685
Activation of AKT2 Reactome R-HSA-165158
Innate Immune System Reactome R-HSA-168249
Immune System Reactome R-HSA-168256
Signaling by VEGF Reactome R-HSA-194138
Signaling by Rho GTPases Reactome R-HSA-194315
RHO GTPase Effectors Reactome R-HSA-195258
TCR signaling Reactome R-HSA-202403
Downstream TCR signaling Reactome R-HSA-202424
Generic Transcription Pathway Reactome R-HSA-212436
PI3K/AKT Signaling in Cancer Reactome R-HSA-2219528
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) Reactome R-HSA-2404192
IGF1R signaling cascade Reactome R-HSA-2428924
IRS-related events triggered by IGF1R Reactome R-HSA-2428928
Fc epsilon receptor (FCERI) signaling Reactome R-HSA-2454202
Role of LAT2/NTAL/LAB on calcium mobilization Reactome R-HSA-2730905
FCERI mediated NF-kB activation Reactome R-HSA-2871837
Integrin signaling Reactome R-HSA-354192
Transcriptional Regulation by TP53 Reactome R-HSA-3700989
Signaling by GPCR Reactome R-HSA-372790
GPCR downstream signalling Reactome R-HSA-388396
Costimulation by the CD28 family Reactome R-HSA-388841
CD28 co-stimulation Reactome R-HSA-389356
CD28 dependent PI3K/Akt signaling Reactome R-HSA-389357
G beta:gamma signalling through PI3Kgamma Reactome R-HSA-392451
G-protein beta:gamma signalling Reactome R-HSA-397795
Post NMDA receptor activation events Reactome R-HSA-438064
VEGFA-VEGFR2 Pathway Reactome R-HSA-4420097
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling Reactome R-HSA-442742
Activation of NMDA receptors and postsynaptic events Reactome R-HSA-442755
RSK activation Reactome R-HSA-444257
VEGFR2 mediated vascular permeability Reactome R-HSA-5218920
VEGFR2 mediated cell proliferation Reactome R-HSA-5218921
CLEC7A (Dectin-1) signaling Reactome R-HSA-5607764
C-type lectin receptors (CLRs) Reactome R-HSA-5621481
RHO GTPases activate PKNs Reactome R-HSA-5625740
Regulation of TP53 Activity Reactome R-HSA-5633007
Diseases of signal transduction by growth factor receptors and second messengers Reactome R-HSA-5663202
Infectious disease Reactome R-HSA-5663205
Constitutive Signaling by AKT1 E17K in Cancer Reactome R-HSA-5674400
Regulation of TP53 Degradation Reactome R-HSA-6804757
Regulation of TP53 Expression and Degradation Reactome R-HSA-6806003
RNA Polymerase II Transcription Reactome R-HSA-73857
Gene expression (Transcription) Reactome R-HSA-74160
Insulin receptor signalling cascade Reactome R-HSA-74751
Signaling by Insulin receptor Reactome R-HSA-74752
Platelet activation, signaling and aggregation Reactome R-HSA-76002
Platelet Aggregation (Plug Formation) Reactome R-HSA-76009
ESR-mediated signaling Reactome R-HSA-8939211
Intracellular signaling by second messengers Reactome R-HSA-9006925
Signaling by Nuclear Receptors Reactome R-HSA-9006931
Signaling by Receptor Tyrosine Kinases Reactome R-HSA-9006934
Extra-nuclear estrogen signaling Reactome R-HSA-9009391
Estrogen-stimulated signaling through PRKCZ Reactome R-HSA-9634635
SARS-CoV-1 Infection Reactome R-HSA-9678108
SARS-CoV Infections Reactome R-HSA-9679506
SARS-CoV-1-host interactions Reactome R-HSA-9692914
SARS-CoV-2 Infection Reactome R-HSA-9694516
SARS-CoV-2-host interactions Reactome R-HSA-9705683
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Reactome R-HSA-9716542
SARS-CoV-1 targets host intracellular signalling and regulatory pathways Reactome R-HSA-9735871
SARS-CoV-2 targets host intracellular signalling and regulatory pathways Reactome R-HSA-9755779
Viral Infection Pathways Reactome R-HSA-9824446
Focal adhesion (WP306) WikiPathways WP306_r116784
Interleukin-11 signaling pathway (WP2332) WikiPathways WP2332_r120725
Integrin-mediated cell adhesion (WP185) WikiPathways WP185_r116785
EGFR tyrosine kinase inhibitor resistance (WP4806) WikiPathways WP4806_r123492
Thyroid stimulating hormone (TSH) signaling pathway (WP2032) WikiPathways WP2032_r122774
ErbB signaling pathway (WP673) WikiPathways WP673_r118930
Glioblastoma signaling pathways (WP2261) WikiPathways WP2261_r123065
T-cell receptor signaling pathway (WP69) WikiPathways WP69_r120966
MicroRNAs in cardiomyocyte hypertrophy (WP1544) WikiPathways WP1544_r121713
Leptin-insulin signaling overlap (WP3935) WikiPathways WP3935_r118425
Focal adhesion: PI3K-Akt-mTOR-signaling pathway (WP3932) WikiPathways WP3932_r124527
Brain-derived neurotrophic factor (BDNF) signaling pathway (WP2380) WikiPathways WP2380_r120727
Insulin signaling (WP481) WikiPathways WP481_r120562
Modulators of TCR signaling and T cell activation (WP5072) WikiPathways WP5072_r115764
B cell receptor signaling pathway (WP23) WikiPathways WP23_r120701
EGF/EGFR signaling pathway (WP437) WikiPathways WP437_r120689
Head and neck squamous cell carcinoma (WP4674) WikiPathways WP4674_r123494
PPAR signaling pathway (WP3942) WikiPathways WP3942_r106517
Serotonin HTR1 group and FOS pathway (WP722) WikiPathways WP722_r120570
Cardiac hypertrophic response (WP2795) WikiPathways WP2795_r117670
Endometrial cancer (WP4155) WikiPathways WP4155_r123347
PI3K-Akt signaling pathway (WP4172) WikiPathways WP4172_r122580
VEGFA-VEGFR2 signaling pathway (WP3888) WikiPathways WP3888_r116782
T-cell activation SARS-CoV-2 (WP5098) WikiPathways WP5098_r119538
Angiopoietin-like protein 8 regulatory pathway (WP3915) WikiPathways WP3915_r123920
Transcripts
Accession Version MolecularType Name NCBI Comments
XM_047434200 1 mRNA transcript variant X5 NC_000016 Reference
XM_024450296 2 mRNA transcript variant X4 NC_000016 Reference
NM_002613 5 mRNA transcript variant 1 NC_000016 Reference
NM_001261816 2 mRNA transcript variant 3 NC_000016 Reference
NM_031268 6 mRNA transcript variant 2 NC_000016 Reference
XM_047434199 1 mRNA transcript variant X3 NC_000016 Reference
XM_047434202 1 mRNA transcript variant X8 NC_000016 Reference
XM_011522523 4 mRNA transcript variant X6 NC_000016 Reference
XM_011522521 4 mRNA transcript variant X1 NC_000016 Reference
XM_047434198 1 mRNA transcript variant X2 NC_000016 Reference
XM_047434201 1 mRNA transcript variant X7 NC_000016 Reference