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PFKFB3

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
General Information
Name 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
Alias
  • 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3
  • 6-phosphofructo-2-kinase/ fructose-2,6-bisphosphatase
  • 6PF-2-K/Fru-2,6-P2ase 3
  • 6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme
  • PFK/FBPase 3
  • fructose-6-phosphate,2-kinase/fructose-2, 6-bisphosphatase
  • inducible 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase
  • renal carcinoma antigen NY-REN-56
Gene_family 6-phosphofructo-2-kinases/fructose-2,6-biphosphatases|MicroRNA protein coding host genes
organism Homo sapiens
entrez_id 5209
location 10p15.1
transcript_count 19
exon_count 21
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez The protein encoded by this gene belongs to a family of bifunctional proteins that are involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate (F2,6BP), and a fructose-2,6-biphosphatase activity that catalyzes the degradation of F2,6BP. This protein is required for cell cycle progression and prevention of apoptosis. It functions as a regulator of cyclin-dependent kinase 1, linking glucose metabolism to cell proliferation and survival in tumor cells. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2016]
    Stringdb 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3; Synthesis and degradation of fructose 2,6-bisphosphate; In the C-terminal section; belongs to the phosphoglycerate mutase family
    nextProt Catalyzes both the synthesis and degradation of fructose 2,6-bisphosphate.
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
PFKFB3 BioGRID ORF1ab GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID PFKFB4 GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID ZRANB1 GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID HSPA8 GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID LATS1 GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID PRKN GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID ORF6 GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID PRMT1 GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID TRIM11 GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID SNX27 GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID LRRTM1 GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID PES1 GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID PFKFB2 GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID ESR1 GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID CLUH GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID YWHAQ GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID PAGE4 GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID YWHAZ GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID YWHAH GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID YWHAG GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID YWHAB GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID FZR1 GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID UFL1 GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID TXNIP GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID CIC GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID NUPR1 GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID WAPL GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID NEK4 GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID HNRNPH1 GeneID BioGRID Affinity Capture-RNA
PFKFB3 BioGRID SH3KBP1 GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID RALBP1 GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID PTPRR GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID PEBP1 GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID FGFR1 GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID EGFR GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID PFKFB1 GeneID BioGRID Two-hybrid
PFKFB3 BioGRID BAG5 GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID DNAJC7 GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID BMH1 GeneID BioGRID Affinity Capture-Western
PFKFB3 BioGRID BMH2 GeneID BioGRID Affinity Capture-Western
PFKFB3 BioGRID UBQLN2 GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID LTN1 GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID VIRMA GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID UBE2M GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID HIRA GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID GCK GeneID BioGRID PCA
PFKFB3 BioGRID HIF1A GeneID BioGRID Co-localization
PFKFB3 BioGRID CBFA2T3 GeneID BioGRID Co-localization
PFKFB3 BioGRID ARNT GeneID BioGRID Co-localization
PFKFB3 BioGRID TRIM25 GeneID BioGRID Affinity Capture-RNA
PFKFB3 BioGRID CYLD GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID H3C6 GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID ASB12 GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID EIF4A3 GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID MAGOH GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID ARRB2 GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID ARRB1 GeneID BioGRID Affinity Capture-MS
PFKFB3 BioGRID ELAVL1 GeneID BioGRID Affinity Capture-RNA
PFKFB3 BioGRID CUL2 GeneID BioGRID Affinity Capture-MS
StringDB
A B experiments database textmining combined score hadb nhadb
PFKFB3 FBXL22 0 0 0 179 1 1
PFKFB3 GSTZ1 0 0 49 151 1 1
PFKFB3 MMP10 0 0 0 158 1 1
PFKFB3 PGA3 0 0 95 151 1 1
PFKFB3 MRPS9 0 0 0 184 1 1
PFKFB3 VDAC1 0 0 165 185 1 2
PFKFB3 RASSF5 0 0 0 206 1 1
PFKFB3 GLUL 0 0 232 267 1 1
PFKFB3 CITED4 0 0 181 181 1 1
PFKFB3 MAGOH 272 0 0 272 1 1
PFKFB3 SKP1 0 0 171 183 1 2
PFKFB3 KDR 0 0 267 333 1 2
PFKFB3 ADSSL1 0 0 0 156 1 1
PFKFB3 MDH2 0 0 242 318 1 1
PFKFB3 FOXP3 0 0 123 261 1 2
PFKFB3 HDHD1 0 0 0 185 1 1
PFKFB3 HNF4A 0 0 170 258 1 1
PFKFB3 UTP20 0 0 74 450 1 1
PFKFB3 CORO1A 0 0 0 150 1 1
PFKFB3 ATG3 0 0 90 185 1 2
PFKFB3 MIF 0 0 155 154 1 2
PFKFB3 GPX6 0 0 0 158 1 1
PFKFB3 SLC2A4 0 0 558 585 1 1
PFKFB3 FSIP2 0 0 86 161 1 1
PFKFB3 FOXO3 0 0 261 275 1 2
PFKFB3 VEGFB 0 0 112 271 1 1
PFKFB3 NME5 0 0 60 150 1 1
PFKFB3 STC2 0 0 202 270 1 1
PFKFB3 PDPR 0 0 123 184 1 1
PFKFB3 EIF4EBP1 0 0 220 220 1 2
PFKFB3 TYMS 0 0 91 156 1 1
PFKFB3 DLD 0 0 134 165 1 2
PFKFB3 PINK1 0 0 66 150 1 2
PFKFB3 GPT 0 0 74 318 1 1
PFKFB3 PHGDH 0 0 261 406 1 1
PFKFB3 TRIM69 0 0 0 161 1 1
PFKFB3 FBXL14 0 0 0 203 1 1
PFKFB3 NADK 0 0 0 266 1 1
PFKFB3 SLC2A12 0 0 180 185 1 1
PFKFB3 SDHD 0 0 150 182 1 1
PFKFB3 FRMD8 0 0 96 342 1 1
PFKFB3 PHKG1 0 0 150 188 1 1
PFKFB3 SLC2A5 0 0 240 287 1 1
PFKFB3 ACACB 0 0 212 236 1 1
PFKFB3 ATP7A 0 0 91 150 1 1
PFKFB3 CA9 0 0 323 323 1 1
PFKFB3 HSPH1 0 0 68 171 1 1
PFKFB3 ACOXL 0 0 0 156 1 1
PFKFB3 SUMO1 0 0 0 164 1 1
PFKFB3 CPT1A 0 0 381 396 1 1
PFKFB3 SMPD2 0 0 42 609 1 1
PFKFB3 DDX3X 0 0 0 160 1 1
PFKFB3 POU2F1 0 0 74 217 1 1
PFKFB3 CBSL 0 0 146 201 1 1
PFKFB3 ALS2CL 0 0 101 630 1 1
PFKFB3 PHKA1 0 0 157 156 1 1
PFKFB3 NAA35 0 0 0 252 1 1
PFKFB3 GLS2 0 0 393 392 1 1
PFKFB3 IDH3A 0 0 181 198 1 1
PFKFB3 BRE 0 0 0 165 1 1
PFKFB3 ACADM 0 0 112 218 1 1
PFKFB3 UCP3 0 0 161 187 1 1
PFKFB3 PDLIM5 0 0 0 195 1 1
PFKFB3 MLX 0 0 230 229 1 1
PFKFB3 SLC1A5 0 0 325 339 1 1
PFKFB3 UBAC2 0 0 0 250 1 1
PFKFB3 FAXDC2 0 0 96 192 1 1
PFKFB3 DPP10 0 0 0 161 1 1
PFKFB3 HSPA2 0 0 0 151 1 1
PFKFB3 IGF1 0 0 216 216 1 2
PFKFB3 WDFY3 0 0 0 181 1 2
PFKFB3 ITPA 0 0 53 198 1 1
PFKFB3 SEC61A2 0 0 102 240 1 1
PFKFB3 PKM 0 0 681 731 1 1
PFKFB3 INTS9 0 0 0 269 1 1
PFKFB3 BCL2A1 0 0 181 204 1 1
PFKFB3 FGF2 0 0 180 179 1 2
PFKFB3 PIGG 0 0 0 186 1 1
PFKFB3 TNNT2 0 0 71 172 1 1
PFKFB3 IFNAR1 0 0 0 189 1 1
PFKFB3 NOS3 0 0 272 295 1 2
PFKFB3 RRM2B 0 0 205 231 1 1
PFKFB3 CD36 0 0 180 179 1 2
PFKFB3 LRRC29 0 0 0 179 1 1
PFKFB3 PRKAA1 0 600 260 714 1 2
PFKFB3 AGXT 0 0 0 158 1 1
PFKFB3 CCND1 0 0 154 153 1 2
PFKFB3 RPIA 0 0 294 350 1 1
PFKFB3 REEP3 0 0 0 196 1 1
PFKFB3 PRPS2 0 0 124 156 1 1
PFKFB3 CHCHD4 0 0 66 275 1 1
PFKFB3 FDXR 0 0 83 183 1 1
PFKFB3 HMGCR 0 0 207 256 1 1
PFKFB3 ALAD 0 0 0 176 1 1
PFKFB3 EIF4E 0 0 112 152 1 2
PFKFB3 HEY1 0 0 107 150 1 1
PFKFB3 YWHAQ 168 0 0 245 1 1
PFKFB3 KAT2B 0 0 108 150 1 1
PFKFB3 PECAM1 0 0 157 163 1 1
PFKFB3 FBXL4 0 0 0 179 1 1
PFKFB3 SNRPA1 0 0 0 206 1 1
PFKFB3 FH 0 0 393 435 1 1
PFKFB3 TXN 0 0 117 176 1 1
PFKFB3 NR1D1 0 0 167 198 1 2
PFKFB3 RHEB 0 0 181 181 1 2
PFKFB3 KLF9 0 0 72 150 1 1
PFKFB3 SFMBT2 0 0 0 158 1 1
PFKFB3 MAPK14 0 0 122 204 1 2
PFKFB3 SREBF1 0 0 358 368 1 1
PFKFB3 GPD2 0 0 122 223 1 1
PFKFB3 CLPB 0 0 0 157 1 1
PFKFB3 MAP3K3 0 0 0 195 1 1
PFKFB3 ATAD2B 0 0 0 159 1 1
PFKFB3 LEP 0 0 210 210 1 1
PFKFB3 AIMP2 0 0 56 192 1 1
PFKFB3 C12orf5 0 900 606 969 1 1
PFKFB3 SLC7A7 0 0 0 216 1 1
PFKFB3 DNM1L 0 0 146 202 1 2
PFKFB3 WIPI1 0 0 0 192 1 2
PFKFB3 PRKAA2 0 600 202 691 1 2
PFKFB3 MAPK7 0 0 67 154 1 1
PFKFB3 VEGFA 0 0 408 433 1 2
PFKFB3 PTEN 0 0 324 346 1 2
PFKFB3 CPT1C 0 0 202 206 1 1
PFKFB3 RBPJ 0 0 48 221 1 1
PFKFB3 NAMPT 0 0 240 342 1 2
PFKFB3 AMPD1 0 0 136 207 1 1
PFKFB3 PPARGC1B 0 0 241 240 1 1
PFKFB3 ATG7 0 0 134 177 1 2
PFKFB3 EGLN2 0 0 233 255 1 1
PFKFB3 CMPK2 0 0 189 203 1 1
PFKFB3 LCAT 0 0 70 169 1 1
PFKFB3 G6PD 0 0 519 545 1 1
PFKFB3 IDH2 0 0 321 363 1 1
PFKFB3 PREB 0 0 49 195 1 1
PFKFB3 MRE11A 0 0 98 276 1 1
PFKFB3 PRKAG3 0 600 194 685 1 1
PFKFB3 SHC1 0 0 48 153 1 1
PFKFB3 ATM 0 0 445 445 1 2
PFKFB3 GPX1 0 0 129 197 1 1
PFKFB3 ADK 0 0 49 166 1 1
PFKFB3 CARKD 0 0 0 162 1 1
PFKFB3 GPX3 0 0 48 164 1 1
PFKFB3 STK39 0 0 0 312 1 1
PFKFB3 LATS1 0 0 93 232 1 1
PFKFB3 WDFY4 0 0 0 181 1 1
PFKFB3 GLYCTK 0 0 112 152 1 1
PFKFB3 AQP9 0 0 103 163 1 1
PFKFB3 IVD 0 0 101 237 1 1
PFKFB3 GBE1 0 0 217 360 1 1
PFKFB3 SPAG6 0 0 54 178 1 1
PFKFB3 PRKAG2 0 600 118 652 1 1
PFKFB3 MAP2K6 0 0 49 267 1 1
PFKFB3 ATG5 0 0 157 156 1 2
PFKFB3 MGAT1 0 0 0 609 1 1
PFKFB3 SPI1 0 0 66 169 1 1
PFKFB3 ACOX1 0 0 147 452 1 1
PFKFB3 SIRT1 0 0 329 340 1 2
PFKFB3 PGM2L1 0 0 205 342 1 1
PFKFB3 PGLS 0 0 74 270 1 1
PFKFB3 OTUD7B 0 0 145 276 1 1
PFKFB3 EEF2K 0 0 66 159 1 2
PFKFB3 ARRDC4 0 0 60 190 1 1
PFKFB3 STT3A 0 0 0 168 1 1
PFKFB3 MAGEB17 0 0 0 206 1 1
PFKFB3 TLR2 0 0 153 162 1 2
PFKFB3 LDHC 0 0 154 229 1 1
PFKFB3 ST6GAL2 0 0 71 236 1 1
PFKFB3 PGLYRP3 0 0 76 189 1 1
PFKFB3 GALE 0 0 0 173 1 1
PFKFB3 PGF 0 0 107 180 1 1
PFKFB3 SLC41A1 0 0 0 155 1 1
PFKFB3 RFC5 0 0 0 183 1 1
PFKFB3 CNDP2 0 0 0 313 1 1
PFKFB3 FOS 0 0 142 167 1 2
PFKFB3 YWHAZ 259 0 81 365 1 1
PFKFB3 IL15RA 0 0 141 207 1 1
PFKFB3 SLCO4A1 0 0 45 168 1 1
PFKFB3 ANGPTL4 0 0 150 215 1 1
PFKFB3 IRG1 0 0 280 280 1 1
PFKFB3 AJUBA 0 0 60 196 1 1
PFKFB3 TIFA 0 0 112 265 1 1
PFKFB3 SUCLG2 0 0 112 191 1 1
PFKFB3 CHMP5 0 0 0 156 1 1
PFKFB3 HIST1H3J 270 0 0 270 1 1
PFKFB3 MYH13 0 0 81 164 1 1
PFKFB3 BTRC 0 0 162 161 1 1
PFKFB3 EPAS1 0 0 180 265 1 2
PFKFB3 FOXO1 0 0 285 297 1 2
PFKFB3 PGD 0 0 325 397 1 1
PFKFB3 SOD2 0 0 159 216 1 2
PFKFB3 ADM 0 0 150 375 1 2
PFKFB3 FABP4 0 0 155 161 1 1
PFKFB3 PI4K2A 0 0 0 168 1 1
PFKFB3 GK 0 0 115 216 1 1
PFKFB3 TBC1D1 0 0 366 367 1 1
PFKFB3 FOLH1 0 0 0 467 1 1
PFKFB3 ADPGK 0 0 66 166 1 1
PFKFB3 MPC2 0 0 159 199 1 1
PFKFB3 DLAT 0 0 126 195 1 1
PFKFB3 FBXL7 0 0 0 179 1 1
PFKFB3 RASSF7 0 0 85 230 1 1
PFKFB3 KLF2 0 0 286 294 1 1
PFKFB3 CHUK 0 0 74 199 1 1
PFKFB3 FBP1 0 650 405 837 1 1
PFKFB3 AK1 0 0 108 158 1 1
PFKFB3 MT-CO2 0 0 74 158 1 1
PFKFB3 DHFR 0 0 96 158 1 1
PFKFB3 CDO1 0 0 92 154 1 1
PFKFB3 SLC25A38 0 0 0 294 1 1
PFKFB3 YWHAH 130 0 0 207 1 1
PFKFB3 GPI 0 0 469 556 1 2
PFKFB3 PDCD11 0 0 0 155 1 1
PFKFB3 RRM2 0 0 140 168 1 1
PFKFB3 TRIB3 0 0 66 160 1 2
PFKFB3 SLC41A2 0 0 0 155 1 1
PFKFB3 GFPT1 0 0 212 235 1 1
PFKFB3 DTYMK 0 0 108 291 1 1
PFKFB3 HSPA1B 0 0 0 201 1 1
PFKFB3 HSPB8 0 0 95 157 1 2
PFKFB3 LIPC 0 0 0 189 1 1
PFKFB3 POU6F2 0 0 0 250 1 1
PFKFB3 NQO1 0 0 108 246 1 2
PFKFB3 ALOX5 0 0 67 229 1 1
PFKFB3 HSPA4L 0 0 67 342 1 1
PFKFB3 LIMS3 0 0 0 369 1 1
PFKFB3 LIMS1 0 0 0 369 1 1
PFKFB3 PRKCQ 0 0 243 395 1 2
PFKFB3 CD28 0 0 146 235 1 1
PFKFB3 CTNNB1 0 0 193 256 1 2
PFKFB3 HRAS 0 0 206 206 1 2
PFKFB3 MFN2 0 0 66 151 1 2
PFKFB3 AK4 0 0 123 274 1 1
PFKFB3 MAGEC2 0 0 0 161 1 1
PFKFB3 FBXL12 0 0 0 179 1 1
PFKFB3 SMPD3 0 0 42 189 1 1
PFKFB3 SUMO2 0 0 0 171 1 1
PFKFB3 NDRG1 0 0 218 329 1 1
PFKFB3 CXCL8 0 0 200 226 1 2
PFKFB3 SLC1A7 0 0 145 163 1 1
PFKFB3 HSPB7 0 0 123 310 1 1
PFKFB3 MAP3K2 0 0 45 199 1 1
PFKFB3 CLK3 0 0 0 162 1 1
PFKFB3 EPHX2 0 0 81 214 1 1
PFKFB3 DNAJB4 0 0 48 296 1 1
PFKFB3 PDE8B 0 0 73 174 1 1
PFKFB3 CXCR4 0 0 193 193 1 2
PFKFB3 MMP1 0 0 0 158 1 1
PFKFB3 MAN2C1 0 0 0 167 1 1
PFKFB3 MTOR 0 0 409 438 1 2
PFKFB3 TRIB2 0 0 46 150 1 1
PFKFB3 CARS 0 0 0 217 1 1
PFKFB3 INPPL1 0 0 0 212 1 1
PFKFB3 ALDH3B2 0 0 73 177 1 1
PFKFB3 SIRT2 0 0 184 215 1 2
PFKFB3 MRPL34 0 0 95 342 1 1
PFKFB3 UGDH 0 0 0 190 1 1
PFKFB3 RGS20 0 0 64 514 1 1
PFKFB3 SHPK 0 0 402 427 1 1
PFKFB3 GLRA3 0 0 0 173 1 1
PFKFB3 ESRRA 0 0 234 240 1 1
PFKFB3 SDHB 0 0 155 184 1 1
PFKFB3 ACO2 0 0 230 250 1 1
PFKFB3 GCKR 0 0 391 392 1 1
PFKFB3 USP9X 0 0 97 197 1 1
PFKFB3 G0S2 0 0 66 169 1 1
PFKFB3 CREB1 0 0 162 181 1 2
PFKFB3 ENO1 0 0 470 534 1 1
PFKFB3 TMCC1 0 0 112 471 1 1
PFKFB3 GAPDH 0 0 422 498 1 2
PFKFB3 GRHPR 0 0 0 209 1 1
PFKFB3 ABL1 0 0 53 161 1 1
PFKFB3 PDHA1 0 0 308 415 1 1
PFKFB3 CNOT1 0 0 0 150 1 1
PFKFB3 NFKB1 0 0 0 159 1 2
PFKFB3 HIRA 270 0 0 288 1 1
PFKFB3 PRODH 0 0 162 163 1 1
PFKFB3 RELA 0 0 96 152 1 2
PFKFB3 STRADA 0 0 167 206 1 1
PFKFB3 G6PC 0 0 404 442 1 1
PFKFB3 RICTOR 0 0 182 209 1 2
PFKFB3 MAGEB16 0 0 0 229 1 1
PFKFB3 GPT2 0 0 122 431 1 1
PFKFB3 DVL1 0 0 0 363 1 1
PFKFB3 EGLN3 0 0 325 442 1 1
PFKFB3 AMN1 0 0 0 179 1 1
PFKFB3 SLC2A6 0 0 320 324 1 1
PFKFB3 SLC25A12 0 0 138 289 1 1
PFKFB3 CLOCK 0 0 166 165 1 2
PFKFB3 TMCO5A 0 0 47 232 1 1
PFKFB3 MAGEB2 0 0 0 206 1 1
PFKFB3 VARS2 0 0 0 395 1 1
PFKFB3 PPARGC1A 0 0 458 457 1 2
PFKFB3 PCK1 0 0 284 368 1 1
PFKFB3 PDGFB 0 0 156 189 1 2
PFKFB3 STK11 0 0 391 420 1 2
PFKFB3 GTF3C3 0 0 0 304 1 1
PFKFB3 FLNA 0 0 47 163 1 1
PFKFB3 SLC2A3 0 0 559 609 1 1
PFKFB3 MDC1 0 0 57 171 1 1
PFKFB3 PDE12 0 0 113 177 1 1
PFKFB3 TMEM45A 0 0 314 464 1 1
PFKFB3 GCDH 0 0 0 156 1 1
PFKFB3 DUSP4 0 0 73 184 1 1
PFKFB3 TEX28 0 0 136 197 1 1
PFKFB3 SUCNR1 0 0 293 293 1 1
PFKFB3 FBXL16 0 0 0 179 1 1
PFKFB3 ME2 0 0 164 184 1 1
PFKFB3 PFKFB2 739 900 755 973 1 1
PFKFB3 FPGS 0 0 0 151 1 1
PFKFB3 CUL2 206 0 48 230 1 1
PFKFB3 SLC7A5 0 0 203 266 1 1
PFKFB3 TP53 0 0 391 390 1 2
PFKFB3 TGM2 0 0 90 152 1 2
PFKFB3 STEAP4 0 0 90 161 1 1
PFKFB3 HMGCS1 0 0 144 197 1 1
PFKFB3 GK2 0 0 47 156 1 1
PFKFB3 MS4A4E 0 0 0 190 1 1
PFKFB3 SLC2A1 0 0 686 705 1 2
PFKFB3 OPLAH 0 0 141 172 1 1
PFKFB3 EGFR 130 0 180 256 1 2
PFKFB3 ECM1 0 0 74 231 1 1
PFKFB3 CHCHD6 0 0 76 399 1 1
PFKFB3 SUCLG1 0 0 140 208 1 1
PFKFB3 RFC3 0 0 0 615 1 1
PFKFB3 HAGH 0 0 114 151 1 1
PFKFB3 FBXL15 0 0 0 179 1 1
PFKFB3 JAK2 0 0 134 173 1 2
PFKFB3 SLC5A1 0 0 164 163 1 1
PFKFB3 CACNA1D 0 0 0 152 1 1
PFKFB3 CRYL1 0 0 90 153 1 1
PFKFB3 REEP2 0 0 0 196 1 1
PFKFB3 ACSS1 0 0 161 264 1 1
PFKFB3 EP300 0 0 194 228 1 2
PFKFB3 IL4 0 0 170 169 1 1
PFKFB3 CLUH 130 0 0 168 1 1
PFKFB3 PKLR 0 0 241 361 1 1
PFKFB3 HKDC1 0 650 180 720 1 1
PFKFB3 BPGM 0 0 112 289 1 1
PFKFB3 RNF123 0 0 0 157 1 1
PFKFB3 SLC26A8 0 0 151 150 1 1
PFKFB3 ERO1L 0 0 167 224 1 1
PFKFB3 DAG1 0 0 0 252 1 1
PFKFB3 CCL2 0 0 181 181 1 2
PFKFB3 ALB 0 0 171 172 1 2
PFKFB3 SGK2 0 0 0 160 1 1
PFKFB3 ASB12 270 0 0 270 1 1
PFKFB3 CASP7 0 0 70 230 1 1
PFKFB3 AANAT 0 0 91 162 1 1
PFKFB3 ZYX 0 0 0 165 1 1
PFKFB3 LONRF3 0 0 0 159 1 1
PFKFB3 DUT 0 0 95 179 1 1
PFKFB3 SIRT6 0 0 213 226 1 2
PFKFB3 ZCCHC14 0 0 0 179 1 1
PFKFB3 SH3PXD2A 0 0 144 175 1 1
PFKFB3 IDH1 0 0 323 365 1 1
PFKFB3 BHLHE40 0 0 108 220 1 1
PFKFB3 CBFA2T3 273 0 113 440 1 1
PFKFB3 REEP1 0 0 0 263 1 1
PFKFB3 MOCS1 0 0 0 196 1 1
PFKFB3 MEST 0 0 0 181 1 1
PFKFB3 STAB2 0 0 60 263 1 1
PFKFB3 KDM2A 0 0 0 218 1 1
PFKFB3 SESN2 0 0 246 255 1 2
PFKFB3 GPD1L 0 0 67 255 1 1
PFKFB3 ACSF3 0 0 163 361 1 1
PFKFB3 HSPA4 0 0 123 220 1 1
PFKFB3 ENSG00000266953 0 0 0 198 1 1
PFKFB3 IGSF3 0 0 66 328 1 1
PFKFB3 PIK3R1 0 0 142 193 1 1
PFKFB3 VARS 0 0 0 444 1 1
PFKFB3 HSP90B1 0 0 55 266 1 1
PFKFB3 TEK 0 0 193 211 1 1
PFKFB3 LPL 0 0 161 179 1 1
PFKFB3 PPARA 0 0 273 281 1 2
PFKFB3 ITIH5 0 0 63 371 1 1
PFKFB3 PDP1 0 0 0 197 1 1
PFKFB3 DUSP12 0 0 116 153 1 1
PFKFB3 CYCS 0 0 181 219 1 2
PFKFB3 EGF 0 0 180 179 1 2
PFKFB3 MLXIP 0 0 285 361 1 1
PFKFB3 EXOSC4 0 0 0 171 1 1
PFKFB3 PFKP 0 650 556 884 1 1
PFKFB3 EXOSC6 0 0 0 207 1 1
PFKFB3 ITIH3 0 0 49 306 1 1
PFKFB3 ITIH2 0 0 105 426 1 1
PFKFB3 MTHFD2 0 0 123 205 1 1
PFKFB3 PYGB 0 0 113 503 1 1
PFKFB3 SLC16A4 0 0 562 562 1 1
PFKFB3 CNGA1 0 0 0 216 1 1
PFKFB3 JUN 0 0 161 181 1 2
PFKFB3 CTDSP2 0 0 73 237 1 1
PFKFB3 FABP3 0 0 123 157 1 1
PFKFB3 ACAD11 0 0 141 232 1 1
PFKFB3 AGPAT1 0 0 66 192 1 1
PFKFB3 INSIG2 0 0 96 264 1 1
PFKFB3 CDC25C 0 0 150 168 1 2
PFKFB3 TBC1D4 0 0 267 268 1 1
PFKFB3 ARIH1 0 0 74 212 1 1
PFKFB3 ARNT 273 0 360 514 1 2
PFKFB3 OTOS 0 0 102 161 1 1
PFKFB3 IRS2 0 0 220 220 1 1
PFKFB3 PRKACB 0 0 0 565 1 1
PFKFB3 NCOA3 0 0 184 223 1 1
PFKFB3 SLC27A6 0 0 113 355 1 1
PFKFB3 TBXAS1 0 0 54 223 1 1
PFKFB3 SUCLA2 0 0 90 248 1 1
PFKFB3 HNRNPH1 270 0 0 270 1 1
PFKFB3 KLHDC10 0 0 0 156 1 1
PFKFB3 LIMS2 0 0 0 369 1 1
PFKFB3 ACAD8 0 0 0 156 1 1
PFKFB3 EHHADH 0 0 47 307 1 1
PFKFB3 UMPS 0 0 0 185 1 1
PFKFB3 B3GALNT2 0 0 71 450 1 1
PFKFB3 ADSS 0 0 0 156 1 1
PFKFB3 C4BPA 0 0 0 189 1 1
PFKFB3 DPP6 0 0 0 161 1 1
PFKFB3 HSP90AA1 0 0 252 291 1 2
PFKFB3 RFC4 0 0 0 183 1 1
PFKFB3 ASS1 0 0 126 358 1 1
PFKFB3 TES 0 0 50 155 1 1
PFKFB3 CABYR 0 0 74 211 1 1
PFKFB3 UBE2E1 0 0 0 190 1 1
PFKFB3 PCK2 0 0 308 350 1 1
PFKFB3 SQSTM1 0 0 399 399 1 2
PFKFB3 SLC16A1 0 0 376 394 1 1
PFKFB3 BNIP3 0 0 324 405 1 2
PFKFB3 MMP9 0 0 155 192 1 2
PFKFB3 STK38 0 0 95 163 1 1
PFKFB3 MAPK3 0 0 150 211 1 2
PFKFB3 TKTL1 0 0 233 300 1 1
PFKFB3 ABCG1 0 0 119 158 1 2
PFKFB3 DHCR24 0 0 44 242 1 1
PFKFB3 CAMK1G 0 0 94 311 1 1
PFKFB3 TSC2 0 0 367 405 1 2
PFKFB3 CDKAL1 0 0 52 166 1 1
PFKFB3 OXSM 0 0 0 177 1 1
PFKFB3 POLR2B 0 0 0 243 1 1
PFKFB3 BNIP3L 0 0 218 273 1 2
PFKFB3 EIF2S1 0 0 96 152 1 2
PFKFB3 LDHB 0 0 420 482 1 1
PFKFB3 RASSF1 0 0 0 190 1 1
PFKFB3 H6PD 0 0 264 465 1 1
PFKFB3 GPCPD1 0 0 113 369 1 1
PFKFB3 RBPJL 0 0 0 179 1 1
PFKFB3 FBXL6 0 0 0 179 1 1
PFKFB3 FBXL13 0 0 0 179 1 1
PFKFB3 HMOX1 0 0 161 175 1 2
PFKFB3 STAT6 0 0 143 174 1 1
PFKFB3 ACLY 0 0 465 511 1 1
PFKFB3 UBE2C 0 0 108 163 1 1
PFKFB3 TMEM225 0 0 75 326 1 1
PFKFB3 EIF2AK3 0 0 173 173 1 2
PFKFB3 COASY 0 0 161 241 1 1
PFKFB3 VHL 0 0 251 254 1 2
PFKFB3 FLT1 0 0 233 372 1 1
PFKFB3 MKL1 0 0 45 179 1 1
PFKFB3 SLK 0 0 171 171 1 1
PFKFB3 SRC 0 0 184 245 1 2
PFKFB3 SCD 0 0 181 200 1 1
PFKFB3 RNASEH1 0 0 0 152 1 1
PFKFB3 YWHAB 130 0 0 211 1 1
PFKFB3 BRIX1 0 0 0 188 1 1
PFKFB3 MCU 0 0 112 153 1 2
PFKFB3 DGAT2 0 0 113 163 1 1
PFKFB3 LRRC2 0 0 0 194 1 1
PFKFB3 FBXL17 0 0 0 179 1 1
PFKFB3 BCAT1 0 0 113 155 1 1
PFKFB3 ENSG00000274276 0 0 129 185 1 1
PFKFB3 GYS2 0 0 260 738 1 1
PFKFB3 ERBB2 0 0 181 181 1 2
PFKFB3 ARG2 0 0 155 177 1 1
PFKFB3 GFPT2 0 0 211 234 1 1
PFKFB3 VLDLR 0 0 47 152 1 1
PFKFB3 MAGEB1 0 0 0 206 1 1
PFKFB3 NMT2 0 0 91 155 1 1
PFKFB3 P4HA1 0 0 284 358 1 1
PFKFB3 DHX35 0 0 82 173 1 1
PFKFB3 GSK3A 0 0 150 351 1 1
PFKFB3 SLC2A8 0 0 135 206 1 1
PFKFB3 SIRT4 0 0 202 230 1 1
PFKFB3 BIRC5 0 0 70 163 1 2
PFKFB3 CCNG2 0 0 167 167 1 1
PFKFB3 ASNS 0 0 146 238 1 1
PFKFB3 PDK3 0 0 195 305 1 1
PFKFB3 PPP2R4 0 0 166 165 1 1
PFKFB3 CCDC60 0 0 155 342 1 1
PFKFB3 PSPH 0 0 156 218 1 1
PFKFB3 ESM1 0 0 91 299 1 1
PFKFB3 IKBKB 0 0 232 290 1 2
PFKFB3 SLC16A7 0 0 293 336 1 1
PFKFB3 CD4 0 0 207 224 1 2
PFKFB3 PRKCG 0 0 0 542 1 1
PFKFB3 RBKS 0 0 96 207 1 1
PFKFB3 DIP2C 0 0 74 192 1 1
PFKFB3 ACOX2 0 0 0 207 1 1
PFKFB3 ENSG00000255767 0 0 0 152 1 1
PFKFB3 REEP6 0 0 0 159 1 1
PFKFB3 AKT1 0 0 490 530 1 2
PFKFB3 PPARG 0 0 323 323 1 2
PFKFB3 MLYCD 0 0 141 163 1 1
PFKFB3 ATXN7 0 0 0 150 1 1
PFKFB3 SLC2A4RG 0 0 233 232 1 1
PFKFB3 PPP1R15A 0 0 60 170 1 2
PFKFB3 PGM5 0 0 45 202 1 1
PFKFB3 MAGEC1 0 0 0 161 1 1
PFKFB3 EEF2 0 0 134 191 1 2
PFKFB3 SLC7A11 0 0 173 218 1 2
PFKFB3 MDH1 0 0 213 283 1 1
PFKFB3 ALDH18A1 0 0 0 386 1 1
PFKFB3 WIPI2 0 0 0 192 1 2
PFKFB3 SLC22A7 0 0 95 262 1 1
PFKFB3 TMCO6 0 0 101 239 1 1
PFKFB3 LPIN2 0 0 55 200 1 1
PFKFB3 PGM1 0 0 193 326 1 1
PFKFB3 MMP3 0 0 82 194 1 1
PFKFB3 ACOT12 0 0 113 377 1 1
PFKFB3 XYLB 0 0 107 259 1 1
PFKFB3 MAGED2 0 0 0 181 1 1
PFKFB3 IDH3B 0 0 138 161 1 1
PFKFB3 TNF 0 0 250 297 1 2
PFKFB3 GTF3C5 0 0 0 330 1 1
PFKFB3 PLOD2 0 0 90 162 1 1
PFKFB3 ARNTL 0 0 234 234 1 1
PFKFB3 CDH5 0 0 204 209 1 1
PFKFB3 PGAM1 0 0 468 574 1 1
PFKFB3 ATF3 0 0 125 252 1 2
PFKFB3 PGK2 0 0 155 278 1 1
PFKFB3 ATOX1 0 0 45 244 1 1
PFKFB3 PFKFB4 739 900 758 973 1 1
PFKFB3 ITIH6 0 0 148 478 1 1
PFKFB3 LIPG 0 0 45 251 1 1
PFKFB3 MMP8 0 0 0 392 1 1
PFKFB3 TXNIP 0 0 229 272 1 2
PFKFB3 ENSG00000164096 0 0 171 171 1 1
PFKFB3 NFKB2 0 0 44 158 1 1
PFKFB3 GCG 0 0 282 298 1 1
PFKFB3 TNFAIP3 0 0 134 159 1 2
PFKFB3 ANKRD37 0 0 143 189 1 1
PFKFB3 PC 0 0 325 357 1 1
PFKFB3 TM4SF4 0 0 67 167 1 1
PFKFB3 ALDOC 0 0 369 444 1 1
PFKFB3 APEH 0 0 0 213 1 1
PFKFB3 CD274 0 0 142 163 1 2
PFKFB3 HK3 0 650 323 773 1 1
PFKFB3 DVL2 0 0 0 347 1 2
PFKFB3 IRS1 0 0 171 171 1 2
PFKFB3 SGK1 0 0 108 159 1 2
PFKFB3 TRMT2A 0 0 0 188 1 1
PFKFB3 LOX 0 0 206 206 1 2
PFKFB3 GLRA1 0 0 0 258 1 1
PFKFB3 SESN1 0 0 141 151 1 1
PFKFB3 CDK1 0 0 230 260 1 2
PFKFB3 SERPINE1 0 0 144 172 1 1
PFKFB3 PDHB 0 0 204 234 1 1
PFKFB3 RPS6KB1 0 0 279 299 1 2
PFKFB3 HELZ2 0 0 0 184 1 1
PFKFB3 CAT 0 0 164 203 1 2
PFKFB3 TIMM17B 0 0 95 260 1 1
PFKFB3 REEP4 0 0 0 239 1 1
PFKFB3 DDIT4 0 0 320 342 1 2
PFKFB3 HPRT1 0 0 134 162 1 1
PFKFB3 CTLA4 0 0 171 202 1 2
PFKFB3 UROS 0 0 0 153 1 1
PFKFB3 DNAJB2 0 0 55 250 1 1
PFKFB3 SLC27A1 0 0 139 174 1 1
PFKFB3 CHORDC1 0 0 95 396 1 1
PFKFB3 LDHA 0 0 744 771 1 2
PFKFB3 UBE2M 270 0 0 270 1 1
PFKFB3 PNMAL2 0 0 0 167 1 1
PFKFB3 G6PC3 0 0 203 222 1 1
PFKFB3 MAB21L3 0 0 127 286 1 1
PFKFB3 RRAGB 0 0 400 400 1 1
PFKFB3 GAPDHS 0 0 94 231 1 1
PFKFB3 NME8 0 0 0 205 1 1
PFKFB3 SCEL 0 0 0 184 1 1
PFKFB3 SLC2A14 0 0 558 601 1 1
PFKFB3 ACSL4 0 0 75 152 1 1
PFKFB3 TRAFD1 0 0 0 252 1 1
PFKFB3 LTA4H 0 0 92 194 1 1
PFKFB3 YARS 0 0 0 271 1 1
PFKFB3 MAGEA4 0 0 0 181 1 1
PFKFB3 IL10 0 0 180 179 1 2
PFKFB3 GIMAP7 0 0 82 315 1 1
PFKFB3 FOSL2 0 0 0 189 1 1
PFKFB3 HCAR1 0 0 193 198 1 1
PFKFB3 GOT2 0 0 183 183 1 1
PFKFB3 SULT2B1 0 0 0 206 1 1
PFKFB3 EML3 0 0 112 169 1 1
PFKFB3 CA12 0 0 194 209 1 1
PFKFB3 PRKCA 0 0 67 554 1 1
PFKFB3 ACVRL1 0 0 0 554 1 1
PFKFB3 PCDHB7 0 0 90 152 1 1
PFKFB3 TM4SF1 0 0 134 283 1 1
PFKFB3 ULK1 0 0 172 231 1 2
PFKFB3 CDK5RAP1 0 0 0 163 1 1
PFKFB3 SPHK1 0 0 113 220 1 2
PFKFB3 AGL 0 0 151 247 1 1
PFKFB3 IRF1 0 0 70 155 1 2
PFKFB3 CAMK1 0 0 90 325 1 1
PFKFB3 PDK4 0 0 341 431 1 1
PFKFB3 SENP3 0 0 0 168 1 1
PFKFB3 SMAD7 0 0 60 151 1 1
PFKFB3 MAGEB4 0 0 0 206 1 1
PFKFB3 ESR1 0 0 195 195 1 2
PFKFB3 LIMCH1 0 0 0 179 1 1
PFKFB3 ADCY8 0 0 70 187 1 1
PFKFB3 ACADS 0 0 65 398 1 1
PFKFB3 KHK 0 0 294 329 1 1
PFKFB3 RGS2 0 0 107 269 1 1
PFKFB3 TRMT2B 0 0 0 188 1 1
PFKFB3 MYOCD 0 0 54 153 1 1
PFKFB3 CHCHD3 0 0 60 444 1 1
PFKFB3 BECN1 0 0 174 175 1 2
PFKFB3 FBXL19 0 0 0 242 1 1
PFKFB3 MOGAT2 0 0 123 238 1 1
PFKFB3 GYS1 0 0 393 513 1 1
PFKFB3 COX4I2 0 0 194 204 1 1
PFKFB3 ACADL 0 0 96 221 1 1
PFKFB3 DUSP1 0 0 134 186 1 1
PFKFB3 DNAJC10 0 0 0 194 1 1
PFKFB3 MPI 0 900 0 908 1 1
PFKFB3 COX6B2 0 0 181 186 1 1
PFKFB3 ACADVL 0 0 52 186 1 1
PFKFB3 PFKFB1 271 900 769 926 1 1
PFKFB3 SNX16 0 0 88 667 1 1
PFKFB3 PES1 182 0 0 181 1 1
PFKFB3 ACOX3 0 0 72 183 1 1
PFKFB3 LPIN1 0 0 166 236 1 2
PFKFB3 KDM6B 0 0 60 158 1 1
PFKFB3 SOCS3 0 0 113 193 1 1
PFKFB3 SFMBT1 0 0 57 400 1 1
PFKFB3 PDHX 0 0 170 212 1 1
PFKFB3 KDM2B 0 0 81 308 1 1
PFKFB3 ENSG00000257767 0 0 0 224 1 1
PFKFB3 ACADSB 0 0 137 453 1 1
PFKFB3 UEVLD 0 0 0 155 1 1
PFKFB3 KRAS 0 0 167 179 1 2
PFKFB3 PGM2 0 0 241 372 1 1
PFKFB3 DTX2 0 0 0 188 1 1
PFKFB3 DCPS 0 0 0 170 1 1
PFKFB3 TKT 0 0 455 502 1 1
PFKFB3 RPS27A 270 0 0 291 1 1
PFKFB3 GSK3B 0 0 87 287 1 2
PFKFB3 C15orf39 0 0 171 171 1 1
PFKFB3 NPLOC4 0 0 0 176 1 1
PFKFB3 AGPAT2 0 0 122 368 1 1
PFKFB3 PIGR 0 0 90 166 1 1
PFKFB3 FBXO39 0 0 0 179 1 1
PFKFB3 CEBPB 0 0 181 227 1 2
PFKFB3 TXNRD1 0 0 73 216 1 1
PFKFB3 BDH1 0 0 123 155 1 1
PFKFB3 TKTL2 0 0 91 170 1 1
PFKFB3 GMPPB 0 0 0 164 1 1
PFKFB3 RPE 0 0 204 288 1 1
PFKFB3 EGLN1 0 0 402 439 1 1
PFKFB3 ATXN7L1 0 0 0 150 1 1
PFKFB3 LMO7 0 0 0 179 1 1
PFKFB3 CASP3 0 0 206 206 1 2
PFKFB3 TEX9 0 0 134 418 1 1
PFKFB3 SLC16A9 0 0 0 161 1 1
PFKFB3 PPM1B 0 0 95 278 1 1
PFKFB3 LIMS3L 0 0 0 369 1 1
PFKFB3 CYBB 0 0 450 450 1 2
PFKFB3 MRPL55 0 0 113 168 1 1
PFKFB3 NEK4 270 0 0 270 1 1
PFKFB3 FSIP1 0 0 75 330 1 1
PFKFB3 SLC7A6 0 0 108 270 1 1
PFKFB3 ENSG00000268643 0 0 0 267 1 1
PFKFB3 SHMT2 0 0 181 272 1 1
PFKFB3 GANAB 0 0 48 184 1 1
PFKFB3 FGGY 0 0 0 157 1 1
PFKFB3 DHCR7 0 0 56 152 1 1
PFKFB3 PSAT1 0 0 145 429 1 1
PFKFB3 ACSL3 0 0 108 182 1 1
PFKFB3 LDHD 0 0 166 205 1 1
PFKFB3 MS4A4A 0 0 92 233 1 1
PFKFB3 PRKAG1 0 600 162 671 1 1
PFKFB3 PRKCB 0 0 0 542 1 2
PFKFB3 HIF1A 273 0 697 774 1 2
PFKFB3 GCK 191 0 560 653 1 1
PFKFB3 PYGL 0 0 289 370 1 1
PFKFB3 SIRT5 0 0 204 217 1 1
PFKFB3 CEP128 0 0 84 294 1 1
PFKFB3 POLR1B 0 0 57 302 1 1
PFKFB3 IL1B 0 0 421 446 1 2
PFKFB3 KIAA1429 270 0 0 285 1 1
PFKFB3 UCP2 0 0 227 247 1 2
PFKFB3 SUMO4 0 0 0 171 1 1
PFKFB3 IL6 0 0 286 303 1 2
PFKFB3 RPS6 0 0 134 157 1 2
PFKFB3 SHMT1 0 0 112 211 1 1
PFKFB3 SLC25A1 0 0 283 325 1 1
PFKFB3 NOTCH1 0 0 286 308 1 2
PFKFB3 SCO2 0 0 402 402 1 1
PFKFB3 SEC61A1 0 0 0 189 1 1
PFKFB3 SMARCAD1 0 0 0 152 1 1
PFKFB3 UPB1 0 0 103 159 1 1
PFKFB3 KPNA1 0 0 481 493 1 1
PFKFB3 GNE 0 0 0 184 1 1
PFKFB3 ANXA5 0 0 201 201 1 2
PFKFB3 CS 0 0 276 331 1 1
PFKFB3 CCNB1 0 0 154 153 1 1
PFKFB3 GLOD4 0 0 0 183 1 1
PFKFB3 AK3 0 0 74 150 1 1
PFKFB3 MGMT 0 0 0 189 1 2
PFKFB3 OSBPL1A 0 0 0 156 1 1
PFKFB3 PDP2 0 0 62 214 1 1
PFKFB3 IST1 0 0 107 346 1 1
PFKFB3 GPD1 0 0 171 338 1 1
PFKFB3 TENC1 0 0 63 395 1 1
PFKFB3 LONP1 0 0 123 175 1 1
PFKFB3 NFATC2IP 0 0 0 164 1 1
PFKFB3 PRKACA 0 0 0 577 1 1
PFKFB3 HSPA1L 0 0 0 201 1 1
PFKFB3 PFKL 0 650 601 895 1 1
PFKFB3 TGFB3 0 0 91 153 1 1
PFKFB3 PDHA2 0 0 90 231 1 1
PFKFB3 NDN 0 0 0 179 1 1
PFKFB3 TLR4 0 0 180 213 1 2
PFKFB3 PHKA2 0 0 182 181 1 1
PFKFB3 LMOD1 0 0 66 234 1 1
PFKFB3 NUDT17 0 0 45 263 1 1
PFKFB3 SNW1 0 0 0 159 1 1
PFKFB3 DAPL1 0 0 0 216 1 1
PFKFB3 PGAM4 0 0 432 545 1 1
PFKFB3 NOS2 0 0 134 161 1 2
PFKFB3 ACSS2 0 0 193 292 1 1
PFKFB3 SLC9A1 0 0 162 205 1 1
PFKFB3 ME1 0 0 166 186 1 1
PFKFB3 LONRF2 0 0 108 218 1 1
PFKFB3 P4HA2 0 0 243 358 1 1
PFKFB3 RGS21 0 0 134 151 1 1
PFKFB3 ZBTB20 0 0 43 262 1 1
PFKFB3 ALDOA 0 0 469 536 1 1
PFKFB3 GLS 0 0 459 459 1 2
PFKFB3 GLDC 0 0 150 260 1 1
PFKFB3 FBP2 0 650 391 834 1 1
PFKFB3 SEMA6A 0 0 71 163 1 1
PFKFB3 NDNL2 0 0 0 181 1 1
PFKFB3 TIGD4 0 0 155 174 1 1
PFKFB3 TPI1 0 0 391 503 1 1
PFKFB3 NR4A3 0 0 55 194 1 1
PFKFB3 ACACA 0 0 322 343 1 1
PFKFB3 HMGCLL1 0 0 103 159 1 1
PFKFB3 PDK1 0 0 561 620 1 2
PFKFB3 MYC 0 0 423 422 1 2
PFKFB3 IL18 0 0 96 170 1 2
PFKFB3 ZDHHC4 0 0 0 208 1 1
PFKFB3 SDHC 0 0 204 225 1 1
PFKFB3 OGDHL 0 0 66 169 1 1
PFKFB3 CAB39 0 0 194 198 1 1
PFKFB3 AKT2 0 0 113 164 1 2
PFKFB3 ACAD9 0 0 0 177 1 1
PFKFB3 IYD 0 0 0 166 1 1
PFKFB3 PFKM 0 650 859 963 1 1
PFKFB3 ENDOV 0 0 0 150 1 1
PFKFB3 HDAC3 0 0 61 331 1 2
PFKFB3 EIF5B 0 0 209 227 1 1
PFKFB3 TFR2 0 0 98 150 1 1
PFKFB3 FBXL3 0 0 66 237 1 1
PFKFB3 ACSL1 0 0 150 197 1 1
PFKFB3 SLC2A2 0 0 334 375 1 1
PFKFB3 HK2 0 650 681 894 1 2
PFKFB3 PLOD1 0 0 218 273 1 1
PFKFB3 LPP 0 0 47 153 1 1
PFKFB3 PRKACG 0 0 0 565 1 1
PFKFB3 PRKX 0 0 0 435 1 1
PFKFB3 TALDO1 0 0 391 543 1 1
PFKFB3 HMBS 0 0 49 220 1 1
PFKFB3 FOXS1 0 0 73 230 1 1
PFKFB3 DECR1 0 0 142 282 1 1
PFKFB3 MOGAT1 0 0 0 167 1 1
PFKFB3 CDK4 0 0 555 572 1 2
PFKFB3 CGA 0 0 54 152 1 2
PFKFB3 NAALAD2 0 0 101 668 1 1
PFKFB3 STAT3 0 0 244 243 1 2
PFKFB3 MST1 0 0 0 290 1 2
PFKFB3 CPT2 0 0 172 190 1 1
PFKFB3 MAGEB6 0 0 0 206 1 1
PFKFB3 C14orf180 0 0 167 167 1 1
PFKFB3 POLR3B 0 0 64 268 1 1
PFKFB3 G3BP2 0 0 448 448 1 1
PFKFB3 CAMKK2 0 0 320 333 1 2
PFKFB3 CACNA1F 0 0 0 152 1 1
PFKFB3 OXSR1 0 0 84 492 1 1
PFKFB3 FAM161A 0 0 0 365 1 1
PFKFB3 DHRS12 0 0 47 312 1 1
PFKFB3 RASSF6 0 0 56 227 1 1
PFKFB3 SDHA 0 0 218 305 1 1
PFKFB3 REEP5 0 0 0 161 1 1
PFKFB3 FAP 0 0 0 161 1 2
PFKFB3 PGK1 0 0 505 577 1 2
PFKFB3 EIF4E2 0 0 67 210 1 1
PFKFB3 FKBP5 0 0 127 204 1 1
PFKFB3 DPP4 0 0 55 173 1 1
PFKFB3 SLC3A2 0 0 139 237 1 1
PFKFB3 AK7 0 0 66 236 1 1
PFKFB3 ABCA1 0 0 138 177 1 2
PFKFB3 YWHAG 131 0 0 208 1 1
PFKFB3 MAPKAPK2 0 0 134 183 1 1
PFKFB3 NDUFA4 0 0 42 184 1 1
PFKFB3 HMGCS2 0 0 143 232 1 1
PFKFB3 CDK6 0 0 466 487 1 2
PFKFB3 MLXIPL 0 0 317 389 1 1
PFKFB3 SCARA5 0 0 45 151 1 1
PFKFB3 PTGIS 0 0 193 193 1 1
PFKFB3 ADIPOQ 0 0 183 183 1 2
PFKFB3 RASSF2 0 0 45 210 1 1
PFKFB3 PRKAB1 0 600 251 747 1 2
PFKFB3 PYGM 0 0 194 426 1 1
PFKFB3 SUMO3 0 0 0 171 1 1
PFKFB3 ARG1 0 0 206 227 1 2
PFKFB3 ADAMTS2 0 0 66 164 1 1
PFKFB3 ENO2 0 0 264 370 1 1
PFKFB3 HSPA6 0 0 57 166 1 1
PFKFB3 GLUD1 0 0 181 279 1 1
PFKFB3 NR3C1 0 0 96 188 1 1
PFKFB3 CPT1B 0 0 88 157 1 1
PFKFB3 GSKIP 0 0 0 336 1 1
PFKFB3 ACAD10 0 0 0 302 1 1
PFKFB3 ENTPD5 0 0 135 174 1 1
PFKFB3 RPTOR 0 0 255 336 1 2
PFKFB3 RAD17 0 0 56 196 1 1
PFKFB3 NMRK2 0 0 92 163 1 1
PFKFB3 HK1 0 650 460 816 1 1
PFKFB3 NRP1 0 0 113 186 1 1
PFKFB3 PRKAB2 0 600 96 670 1 1
PFKFB3 AKR1B1 0 0 118 166 1 1
PFKFB3 UBE2Q2 0 0 74 152 1 1
PFKFB3 FASN 0 0 390 391 1 2
PFKFB3 EIF4A3 196 0 0 216 1 1
PFKFB3 GLUD2 0 0 0 156 1 1
PFKFB3 SLC16A3 0 0 558 570 1 1
PFKFB3 AKT1S1 0 0 142 237 1 1
PFKFB3 RFC2 0 0 0 183 1 1
PFKFB3 HSPA1A 0 0 66 240 1 1
PFKFB3 OGDH 0 0 194 283 1 1
PFKFB3 MAP2K3 0 0 0 183 1 1
PFKFB3 PER2 0 0 139 157 1 1
PFKFB3 DLL4 0 0 181 181 1 1
PFKFB3 NAALADL1 0 0 0 153 1 1
PFKFB3 ARID5A 0 0 61 224 1 1
PFKFB3 IDI2 0 0 96 158 1 1
PFKFB3 DVL3 0 0 0 347 1 1
PFKFB3 CAMK1D 0 0 81 206 1 1
PFKFB3 CASS4 0 0 0 177 1 1
PFKFB3 CSTF3 0 0 0 190 1 1
PFKFB3 IGFBP3 0 0 123 155 1 2
PFKFB3 TFAM 0 0 246 310 1 2
PFKFB3 ANGPT2 0 0 134 290 1 1
PFKFB3 ATP5B 0 0 112 150 1 1
PFKFB3 MMP2 0 0 134 151 1 2
PFKFB3 PNCK 0 0 113 450 1 1
PFKFB3 FZR1 0 0 160 190 1 1
PFKFB3 GSR 0 0 210 247 1 1
PFKFB3 INSR 0 0 165 198 1 1
PFKFB3 HSPA8 0 0 72 324 1 2
PFKFB3 CRTC2 0 0 194 221 1 1
PFKFB3 RHOA 0 0 87 151 1 2
PFKFB3 GUCY1A3 0 0 57 192 1 1
PFKFB3 PGAM2 0 0 246 396 1 1
PFKFB3 TIMM17A 0 0 49 427 1 1
PFKFB3 PDK2 0 0 193 303 1 1
PFKFB3 SIRT7 0 0 164 177 1 2
PFKFB3 MXI1 0 0 234 247 1 1
PFKFB3 ALDOB 0 0 228 310 1 1
PFKFB3 PNPLA2 0 0 139 184 1 2
PFKFB3 COX4I1 0 0 242 241 1 1
PFKFB3 KY 0 0 107 205 1 1
PFKFB3 INS 0 0 468 468 1 2
PFKFB3 AK2 0 0 0 157 1 1
PFKFB3 ACTB 0 0 370 379 1 2
PFKFB3 ZCCHC2 0 0 0 179 1 1
PFKFB3 KEAP1 0 0 150 185 1 2
PFKFB3 ENO3 0 0 195 276 1 1
PFKFB3 ANGPT1 0 0 134 160 1 1
PFKFB3 SIRT3 0 0 320 345 1 2
Ontologies
ID Category Term Effect Evidence PubMed
GO:0003873 Molecular Function 6-phosphofructo-2-kinase activity enables IBA
GO:0003873 Molecular Function 6-phosphofructo-2-kinase activity enables IDA
GO:0003873 Molecular Function 6-phosphofructo-2-kinase activity enables NAS
GO:0005524 Molecular Function ATP binding enables IEA
GO:0004331 Molecular Function fructose-2,6-bisphosphate 2-phosphatase activity enables IBA
GO:0005515 Molecular Function protein binding enables IPI
GO:0046835 Biological Process carbohydrate phosphorylation involved_in IEA
GO:0006003 Biological Process fructose 2,6-bisphosphate metabolic process involved_in IBA
GO:0006000 Biological Process fructose metabolic process involved_in IEA
GO:0005829 Cellular Component cytosol is_active_in IBA
GO:0005829 Cellular Component cytosol located_in TAS
GO:0005654 Cellular Component nucleoplasm located_in IDA
Pathways
Name DB ID
Metabolism Reactome R-HSA-1430728
Glycolysis Reactome R-HSA-70171
Glucose metabolism Reactome R-HSA-70326
Metabolism of carbohydrates Reactome R-HSA-71387
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism Reactome R-HSA-9634600
Focal adhesion: PI3K-Akt-mTOR-signaling pathway (WP3932) WikiPathways WP3932_r124527
AMP-activated protein kinase signaling (WP1403) WikiPathways WP1403_r123620
Transcripts
Accession Version MolecularType Name NCBI Comments
NR_136554 2 miscRNA transcript variant 7 NC_000010 Reference
XM_047425341 1 mRNA transcript variant X2 NC_000010 Reference
NM_001323016 2 mRNA transcript variant 5 NC_000010 Reference
NM_001145443 3 mRNA transcript variant 2 NC_000010 Reference
XM_047425347 1 mRNA transcript variant X9 NC_000010 Reference
XM_047425346 1 mRNA transcript variant X7 NC_000010 Reference
XM_047425343 1 mRNA transcript variant X4 NC_000010 Reference
NM_001282630 3 mRNA transcript variant 3 NC_000010 Reference
NM_001363545 2 mRNA transcript variant 8 NC_000010 Reference
NM_001323017 2 mRNA transcript variant 6 NC_000010 Reference
NM_001314063 2 mRNA transcript variant 4 NC_000010 Reference
NM_004566 4 mRNA transcript variant 1 NC_000010 Reference
XM_005252464 2 mRNA transcript variant X8 NC_000010 Reference
XM_047425344 1 mRNA transcript variant X5 NC_000010 Reference
XM_047425342 1 mRNA transcript variant X3 NC_000010 Reference
XM_011519493 2 mRNA transcript variant X10 NC_000010 Reference
XM_017016329 2 mRNA transcript variant X1 NC_000010 Reference
XM_047425345 1 mRNA transcript variant X6 NC_000010 Reference
XM_047425349 1 mRNA transcript variant X11 NC_000010 Reference