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PMAIP1

phorbol-12-myristate-13-acetate-induced protein 1
General Information
Name phorbol-12-myristate-13-acetate-induced protein 1
Alias
  • phorbol-12-myristate-13-acetate-induced protein 1
  • PMA-induced protein 1
  • adult T cell leukemia-derived PMA-responsive
  • immediate-early-response protein APR
  • protein Noxa
Gene_family BCL2 homology region 3 (BH3) only
organism Homo sapiens
entrez_id 5366
location 18q21.32
transcript_count 6
exon_count 2
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez This gene belongs to a pro-apoptotic subfamily within the BCL-2 protein family, referred to as the BCL-2 homology domain 3 (BH3)-only subfamily, which determine whether a cell commits to apoptosis. In response to death-inducing stimuli, BH3-only members inhibit the anti-apoptotic BCL-2 family members, which under steady-state conditions keep the multi-BH domain proteins BAX and BAK, in an inactive state. [provided by RefSeq, Aug 2020]
    Stringdb Phorbol-12-myristate-13-acetate-induced protein 1; Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1; Belongs to the PMAIP1 family
    nextProt Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
PMAIP1 BioGRID BCL2L12 GeneID BioGRID Negative Genetic
PMAIP1 BioGRID BNIP3L GeneID BioGRID Negative Genetic
PMAIP1 BioGRID BIK GeneID BioGRID Negative Genetic
PMAIP1 BioGRID BAD GeneID BioGRID Negative Genetic
PMAIP1 BioGRID MCL1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-localization; Protein-peptide; Reconstituted Complex
PMAIP1 BioGRID SQSTM1 GeneID BioGRID Affinity Capture-Western
PMAIP1 BioGRID UBE2F GeneID BioGRID Affinity Capture-Western
PMAIP1 BioGRID PSMC5 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID PRKCSH GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID PPA1 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID PHB1 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID ETFA GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID EPB41L2 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID DSG2 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID DDT GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID DDOST GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID CSE1L GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID COX7C GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID COX7A2 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID COX4I1 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID CNP GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID CDC42 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID BTF3 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID BSG GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID ATP2B4 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID ATP2B1 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID ATP2A2 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID ATP1B3 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID ATP1B1 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID ATP1A1 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID RHOA GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID ARF4 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID APEX1 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID ANXA2 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID ALDH3A2 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID AK2 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID CKMT1A GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID COA6 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID KLRG2 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID ATP11C GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID STT3B GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID MTPN GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID DCD GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID CCDC124 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID SFXN1 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID BTF3L4 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID RIOK1 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID RAB1B GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID ANP32E GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID TXNDC5 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID TMX1 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID DNAJC5 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID ACBD3 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID SRPRB GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID RAP2C GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID AGTRAP GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID GNG12 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID TMEM30A GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID VPS35 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID LRRC59 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID ARL8B GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID KLHDC4 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID TMED9 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID NDUFB11 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID RAB14 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID HACD3 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID ZNF593 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID STOML2 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID ERO1A GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID TBL2 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID TBC1D10B GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID HIGD1A GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID HYPK GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID PITPNB GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID STX12 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID ESYT1 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID EPB41L3 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID DNAJC8 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID RRAS2 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID ERLIN2 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID STMN2 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID NUDT21 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID RAB35 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID SNRNP27 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID TMED10 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID CKAP4 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID TMED2 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID RAB10 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID PGRMC1 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID PRDX4 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID ANP32B GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID HMGN4 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID STUB1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity
PMAIP1 BioGRID ZMPSTE24 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID BCAP31 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID PDIA6 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID SCAMP3 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID COX17 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID RBX1 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID EIF5B GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID GNA14 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID PRDX6 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID SEC22B GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID ATP6V1G1 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID ZRANB2 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID COX5A GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID RAB9A GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID VAMP3 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID COPB2 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID VAPA GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID CPNE3 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID SNAP23 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID RAB11A GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID YARS1 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID STX7 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID SLC7A5 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID RAB7A GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID EZR GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID UBE2N GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID UBE2D2 GeneID BioGRID Reconstituted Complex
PMAIP1 BioGRID UBE2D1 GeneID BioGRID Reconstituted Complex
PMAIP1 BioGRID DNAJC7 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID TPD52L2 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID TFRC GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID TALDO1 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID VAMP7 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID STXBP3 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID STX4 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID SNX2 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID SLC16A1 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID SLC12A2 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID SLC7A1 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID SLC3A2 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID SLC1A5 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID SLC1A3 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID RPN2 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID RP2 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID RAP1A GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID RALA GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID RAB5C GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID RAB6A GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID RAB5A GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID RAB2A GeneID BioGRID Affinity Capture-MS; Two-hybrid
PMAIP1 BioGRID PEBP1 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID P4HB GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID NEDD8 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID COX2 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID CD99 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID MDH1 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID LMAN1 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID KRAS GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID KPNA2 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID JUP GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID STT3A GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID IGHG2 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID IGF2R GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID HMGN1 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID HLA-B GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID HLA-A GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID GNB2 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID GNB1 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID GNAS GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID GNAI3 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID GNAI2 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID GDI2 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID FKBP3 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID FKBP1A GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID Mcl1 GeneID BioGRID Affinity Capture-Western
PMAIP1 BioGRID CUL5 GeneID BioGRID Affinity Capture-Western; Synthetic Rescue
PMAIP1 BioGRID RNF7 GeneID BioGRID Biochemical Activity
PMAIP1 BioGRID MED4 GeneID BioGRID Affinity Capture-MS
PMAIP1 BioGRID BCL2L1 GeneID BioGRID Affinity Capture-Western; Protein-peptide
PMAIP1 BioGRID UCHL1 GeneID BioGRID Affinity Capture-Western
PMAIP1 BioGRID ELAVL1 GeneID BioGRID Affinity Capture-RNA
PMAIP1 BioGRID GSK3B GeneID BioGRID Two-hybrid
PMAIP1 BioGRID HUWE1 GeneID BioGRID Affinity Capture-Western
PMAIP1 Protein ZBTB16 GeneID HPRD
PMAIP1 Protein MCL1 GeneID HPRD
PMAIP1 Protein PPBP GeneID HPRD
PMAIP1 Protein BCL2A1 GeneID HPRD
PMAIP1 Protein BAX GeneID HPRD
PMAIP1 Protein BCL2L1 GeneID HPRD
PMAIP1 Protein BCL2 GeneID HPRD
PMAIP1 BioGRID BCL2 GeneID BioGRID Affinity Capture-Western; Protein-peptide
PMAIP1 BioGRID ZBTB16 GeneID BioGRID Two-hybrid
PMAIP1 BioGRID BCL2A1 GeneID BioGRID Protein-peptide
PMAIP1 BioGRID BAX GeneID BioGRID Affinity Capture-Western
PMAIP1 Nucleotide MYC GeneID BIND c-Myc interacts with NOXA promoter.
PMAIP1 Nucleotide ZBTB17 GeneID BIND Miz1 interacts with NOXA promoter.
PMAIP1 Protein BCL2A1 GeneID BIND Noxa interacts with A1. This interaction was modelled on a demonstrated interaction between human Noxa and mouse A1.
StringDB
A B experiments database textmining combined score hadb nhadb
PMAIP1 DAXX 0 0 193 193 1 1
PMAIP1 TNFRSF21 0 0 213 213 1 1
PMAIP1 PSMB9 0 0 156 155 1 1
PMAIP1 PTGS2 0 0 235 308 1 2
PMAIP1 NQO1 0 0 193 193 1 2
PMAIP1 CASP3 0 0 736 742 1 2
PMAIP1 RPS10-NUDT3 0 0 154 153 1 1
PMAIP1 ATG4D 0 0 154 153 1 2
PMAIP1 RNF152 0 0 139 426 1 1
PMAIP1 TRIB3 0 0 243 260 1 2
PMAIP1 REL 0 0 287 286 1 2
PMAIP1 BRCA2 0 0 210 239 1 1
PMAIP1 NCAPH 0 0 49 261 1 1
PMAIP1 HDAC11 0 0 140 155 1 1
PMAIP1 CYBB 0 0 423 423 1 2
PMAIP1 CD5 0 0 150 168 1 1
PMAIP1 CD28 0 0 157 156 1 1
PMAIP1 NR2C2 0 0 0 214 1 1
PMAIP1 NOTCH2 0 0 156 155 1 1
PMAIP1 TNFSF13B 0 0 180 179 1 1
PMAIP1 ATG12 0 0 335 335 1 2
PMAIP1 STS 0 0 0 355 1 1
PMAIP1 TNFRSF10B 0 0 681 688 1 2
PMAIP1 CUL3 0 0 143 157 1 2
PMAIP1 CHUK 0 0 255 254 1 1
PMAIP1 HIST2H4A 0 0 167 167 1 1
PMAIP1 DTL 0 0 86 167 1 1
PMAIP1 CASP4 0 0 337 347 1 2
PMAIP1 CDKN2A 0 0 469 477 1 2
PMAIP1 SFN 0 0 520 540 1 2
PMAIP1 CCNG1 0 0 391 408 1 1
PMAIP1 MTCH2 0 0 209 216 1 1
PMAIP1 GSK3B 64 0 160 205 1 2
PMAIP1 XRCC5 0 0 208 208 1 1
PMAIP1 PRDM1 0 0 164 163 1 1
PMAIP1 HDAC1 0 0 324 340 1 2
PMAIP1 RRM2 0 0 150 201 1 1
PMAIP1 RIPK1 0 0 326 325 1 2
PMAIP1 ATG16L1 0 0 155 154 1 2
PMAIP1 TXNRD1 0 0 212 229 1 1
PMAIP1 BIRC7 0 0 340 350 1 1
PMAIP1 STAT5A 0 0 240 239 1 1
PMAIP1 RAD1 0 0 156 155 1 1
PMAIP1 DEPTOR 0 0 234 234 1 2
PMAIP1 XAF1 0 0 268 268 1 1
PMAIP1 YWHAZ 0 0 388 388 1 1
PMAIP1 FOS 0 0 276 276 1 2
PMAIP1 FASLG 0 0 506 506 1 1
PMAIP1 MATK 0 0 174 173 1 1
PMAIP1 AIFM3 0 0 85 292 1 1
PMAIP1 KRAS 0 0 342 343 1 2
PMAIP1 SH2B1 0 0 48 260 1 1
PMAIP1 FOXO1 0 0 372 372 1 2
PMAIP1 PKN2 0 0 57 156 1 1
PMAIP1 CDK9 0 0 320 319 1 1
PMAIP1 SOD2 0 0 264 264 1 2
PMAIP1 HSPA5 0 0 470 470 1 2
PMAIP1 E2F1 0 900 292 930 1 2
PMAIP1 NRAS 0 0 254 277 1 1
PMAIP1 KDM2B 0 0 292 292 1 1
PMAIP1 BTRC 0 0 270 270 1 1
PMAIP1 CDKN2B 0 0 246 262 1 1
PMAIP1 DUSP1 0 0 185 185 1 1
PMAIP1 MAPK11 0 0 99 167 1 1
PMAIP1 PHB 0 0 160 159 1 1
PMAIP1 MET 0 0 174 173 1 2
PMAIP1 CDKN2C 0 0 167 167 1 1
PMAIP1 SDC1 0 0 232 231 1 1
PMAIP1 ABCB1 0 0 160 159 1 2
PMAIP1 THBS1 0 0 170 169 1 1
PMAIP1 BECN1 0 0 616 617 1 2
PMAIP1 IL2 0 0 233 232 1 1
PMAIP1 WEE1 0 0 334 354 1 1
PMAIP1 CDT1 0 0 325 355 1 1
PMAIP1 LPIN1 0 0 124 178 1 2
PMAIP1 DNAJB9 0 0 245 244 1 2
PMAIP1 NOD1 0 0 433 433 1 2
PMAIP1 BCL2L15 0 0 257 256 1 1
PMAIP1 PARP2 0 0 134 161 1 1
PMAIP1 CDC25A 0 0 262 305 1 1
PMAIP1 ATG5 0 0 423 422 1 2
PMAIP1 KSR1 0 0 90 186 1 1
PMAIP1 BCL2L14 0 0 391 457 1 1
PMAIP1 HIPK2 0 0 414 414 1 2
PMAIP1 HEMGN 0 0 49 307 1 1
PMAIP1 SP3 0 0 88 207 1 1
PMAIP1 TP63 0 0 213 299 1 2
PMAIP1 YAP1 0 0 207 207 1 2
PMAIP1 XBP1 0 0 458 457 1 2
PMAIP1 IRF1 0 0 410 422 1 2
PMAIP1 PRL 0 0 57 181 1 1
PMAIP1 CTSB 0 0 203 203 1 2
PMAIP1 LMNB1 0 0 150 191 1 1
PMAIP1 NOX1 0 0 322 321 1 1
PMAIP1 TSPYL5 0 0 90 265 1 1
PMAIP1 TP53BP1 0 0 260 260 1 1
PMAIP1 SIRT1 0 0 391 390 1 2
PMAIP1 MCL1 902 0 989 999 1 2
PMAIP1 MAP3K5 0 0 417 416 1 1
PMAIP1 ITGAM 0 0 156 155 1 1
PMAIP1 IP6K2 0 0 193 193 1 1
PMAIP1 RGS1 0 0 54 218 1 1
PMAIP1 COPS5 0 0 201 201 1 1
PMAIP1 DUOX2 0 0 155 154 1 1
PMAIP1 IRF5 0 0 383 382 1 1
PMAIP1 NCL 0 0 134 150 1 2
PMAIP1 IFNB1 0 0 262 262 1 1
PMAIP1 MSH2 0 0 134 155 1 1
PMAIP1 ESR1 0 0 325 325 1 2
PMAIP1 RPS6KA1 0 0 219 219 1 1
PMAIP1 RPL5 0 0 140 166 1 1
PMAIP1 ULK1 0 0 255 254 1 2
PMAIP1 CDC25B 0 0 210 210 1 1
PMAIP1 PLK3 0 0 234 281 1 1
PMAIP1 LRRC8D 0 0 108 163 1 1
PMAIP1 PSMD14 0 0 143 153 1 1
PMAIP1 TBP 0 0 187 187 1 1
PMAIP1 GPX1 0 0 155 154 1 1
PMAIP1 IKBKG 0 0 210 210 1 1
PMAIP1 ATG10 0 0 162 161 1 2
PMAIP1 NCF2 0 0 281 298 1 1
PMAIP1 GLI1 0 0 136 151 1 2
PMAIP1 HSPB1 0 0 236 236 1 2
PMAIP1 VAV1 0 0 134 156 1 1
PMAIP1 HSPB2 0 0 241 240 1 1
PMAIP1 TERT 0 0 181 195 1 2
PMAIP1 SERPINB5 0 0 234 234 1 1
PMAIP1 SPHK2 0 0 145 228 1 1
PMAIP1 DFFB 0 0 283 282 1 1
PMAIP1 MAP1LC3B 0 0 302 310 1 2
PMAIP1 SPHK1 0 0 113 199 1 2
PMAIP1 ATG7 0 0 374 374 1 2
PMAIP1 GDF15 0 0 252 366 1 1
PMAIP1 BTG2 0 0 322 321 1 1
PMAIP1 ACTG1 0 0 173 173 1 1
PMAIP1 UBE2S 0 0 120 152 1 1
PMAIP1 CDK7 0 0 210 229 1 1
PMAIP1 SNAI1 0 0 228 245 1 1
PMAIP1 IL10 0 0 164 163 1 2
PMAIP1 FLT3 0 0 271 271 1 2
PMAIP1 NPM1 0 0 172 221 1 1
PMAIP1 RBPJ 0 0 330 330 1 1
PMAIP1 TNFRSF10C 0 0 263 263 1 1
PMAIP1 ATM 0 0 561 567 1 2
PMAIP1 SHC1 0 0 150 150 1 1
PMAIP1 MDM4 0 0 507 510 1 1
PMAIP1 EFHD2 0 0 48 217 1 1
PMAIP1 LDHA 0 0 167 185 1 2
PMAIP1 AMBRA1 0 0 218 218 1 2
PMAIP1 C12orf5 0 0 493 500 1 1
PMAIP1 COMMD3-BMI1 0 0 322 326 1 1
PMAIP1 NFKBIA 0 0 401 400 1 2
PMAIP1 KIT 0 0 280 280 1 2
PMAIP1 SYK 0 0 167 180 1 2
PMAIP1 UBE2M 0 0 300 300 1 1
PMAIP1 RCHY1 0 0 323 323 1 1
PMAIP1 KAT5 0 0 260 260 1 1
PMAIP1 MASTL 0 0 0 158 1 1
PMAIP1 LRRFIP2 0 0 54 222 1 1
PMAIP1 MAPK14 0 0 193 254 1 2
PMAIP1 HIST1H4A 0 0 167 167 1 1
PMAIP1 MAPK10 0 0 396 396 1 2
PMAIP1 TP53BP2 0 0 294 294 1 2
PMAIP1 E2F3 0 0 207 235 1 1
PMAIP1 HIST1H4K 0 0 167 167 1 1
PMAIP1 VEGFA 0 0 369 369 1 2
PMAIP1 IRF4 0 0 154 153 1 1
PMAIP1 SLC2A14 0 0 124 156 1 1
PMAIP1 PTEN 0 0 468 468 1 2
PMAIP1 CYFIP2 0 0 171 171 1 1
PMAIP1 DNM1L 0 0 215 215 1 2
PMAIP1 E2F5 0 0 166 165 1 1
PMAIP1 POU5F1 0 0 176 206 1 2
PMAIP1 TSPAN14 0 0 140 166 1 1
PMAIP1 ALDH5A1 0 0 0 189 1 1
PMAIP1 CANX 0 0 201 201 1 2
PMAIP1 TXN 0 0 246 271 1 1
PMAIP1 HRK 0 0 825 828 1 1
PMAIP1 C2orf47 0 0 164 163 1 1
PMAIP1 CCNE1 0 0 181 248 1 1
PMAIP1 CAT 0 0 322 321 1 2
PMAIP1 GFI1 0 0 113 226 1 1
PMAIP1 CTLA4 0 0 195 195 1 2
PMAIP1 DFFA 0 0 213 213 1 1
PMAIP1 TP53I3 0 0 365 365 1 1
PMAIP1 E2F8 0 0 143 168 1 1
PMAIP1 CD38 0 0 194 194 1 2
PMAIP1 BCL2 799 800 406 976 1 2
PMAIP1 MYB 0 0 150 150 1 1
PMAIP1 HIST2H4B 0 0 167 167 1 1
PMAIP1 AVEN 0 0 204 204 1 1
PMAIP1 BAK1 0 0 564 622 1 2
PMAIP1 FEM1B 0 0 63 318 1 1
PMAIP1 HPRT1 0 0 193 213 1 1
PMAIP1 DDIT4 0 0 265 281 1 2
PMAIP1 RHEB 0 0 151 150 1 2
PMAIP1 ATR 0 0 289 288 1 2
PMAIP1 CD19 0 0 241 240 1 1
PMAIP1 BCL2L2 488 0 937 970 1 1
PMAIP1 NCF1 0 0 142 160 1 1
PMAIP1 GRAMD4 0 0 245 324 1 1
PMAIP1 RRM2B 0 0 464 463 1 1
PMAIP1 TNFRSF10D 0 0 264 282 1 1
PMAIP1 CCND1 0 0 504 504 1 2
PMAIP1 DDB2 0 0 310 309 1 1
PMAIP1 RPRM 0 0 391 401 1 1
PMAIP1 CRBN 0 0 151 150 1 1
PMAIP1 ZBTB32 0 0 148 163 1 1
PMAIP1 PRKDC 0 0 233 232 1 2
PMAIP1 SERPINE1 0 0 205 205 1 1
PMAIP1 CDK1 0 0 417 463 1 2
PMAIP1 EIF4E 0 0 235 235 1 2
PMAIP1 HIST1H4B 0 0 167 167 1 1
PMAIP1 PGR 0 0 164 163 1 1
PMAIP1 KAT2B 0 0 193 193 1 1
PMAIP1 REM1 0 0 46 152 1 1
PMAIP1 RPS6KB1 0 0 320 319 1 2
PMAIP1 BAD 0 0 466 465 1 2
PMAIP1 EGR2 0 0 72 187 1 1
PMAIP1 LOX 0 0 162 161 1 2
PMAIP1 FDXR 0 0 261 261 1 1
PMAIP1 HSPA9 0 0 162 161 1 1
PMAIP1 TOPBP1 0 0 134 153 1 1
PMAIP1 NOX5 0 0 218 218 1 1
PMAIP1 IFT43 0 0 156 155 1 1
PMAIP1 NTRK1 0 0 124 178 1 1
PMAIP1 SESN1 0 0 427 426 1 1
PMAIP1 ATF3 0 0 503 527 1 2
PMAIP1 GADD45A 0 0 630 641 1 1
PMAIP1 BTK 0 0 243 242 1 1
PMAIP1 SOCS1 0 0 218 237 1 1
PMAIP1 CCND3 0 0 166 165 1 1
PMAIP1 UVRAG 0 0 240 239 1 2
PMAIP1 IGF1 0 0 261 261 1 2
PMAIP1 IRF7 0 0 296 296 1 1
PMAIP1 MAPK1 0 0 216 221 1 2
PMAIP1 TNFAIP3 0 0 184 214 1 2
PMAIP1 NFKB2 0 0 218 218 1 1
PMAIP1 EDEM1 0 0 181 181 1 2
PMAIP1 CCND2 0 0 233 232 1 1
PMAIP1 HIST1H4H 0 0 167 167 1 1
PMAIP1 IFNAR1 0 0 163 163 1 1
PMAIP1 RPS6KA2 0 0 195 195 1 1
PMAIP1 BMF 0 0 802 811 1 1
PMAIP1 TXNIP 0 0 134 153 1 2
PMAIP1 BCL2A1 893 0 930 993 1 1
PMAIP1 RELB 0 0 241 240 1 2
PMAIP1 DRAM1 0 0 450 471 1 2
PMAIP1 BCAP31 0 0 194 194 1 1
PMAIP1 FGF2 0 0 147 162 1 2
PMAIP1 GLS2 0 0 339 339 1 1
PMAIP1 VCL 0 0 206 206 1 1
PMAIP1 NAIP 0 0 243 242 1 1
PMAIP1 FIS1 0 0 164 163 1 2
PMAIP1 USP14 0 0 181 181 1 2
PMAIP1 PPP1R15A 0 0 459 459 1 2
PMAIP1 SLC7A11 0 0 261 261 1 2
PMAIP1 C22orf29 0 0 873 873 1 1
PMAIP1 LHX9 0 0 0 163 1 1
PMAIP1 TNF 0 0 419 440 1 2
PMAIP1 CASP2 0 0 460 460 1 1
PMAIP1 AEN 0 0 150 206 1 1
PMAIP1 SLC1A5 0 0 113 165 1 1
PMAIP1 CD44 0 0 407 407 1 2
PMAIP1 KIAA0141 0 0 181 181 1 1
PMAIP1 IL7 0 0 213 213 1 1
PMAIP1 DUOX1 0 0 166 165 1 1
PMAIP1 KLF4 0 0 143 158 1 2
PMAIP1 IKBKB 0 0 254 254 1 2
PMAIP1 ATF6 0 0 456 456 1 2
PMAIP1 HUS1 0 0 152 151 1 1
PMAIP1 ZNF398 0 0 0 154 1 1
PMAIP1 SPEN 0 0 0 214 1 1
PMAIP1 RUNX2 0 0 233 232 1 2
PMAIP1 PPP2R4 0 0 215 215 1 1
PMAIP1 XIAP 0 0 636 651 1 2
PMAIP1 E2F4 0 0 171 171 1 1
PMAIP1 ZMAT3 0 0 454 454 1 1
PMAIP1 MKI67 0 0 74 212 1 2
PMAIP1 CSF2 0 0 163 163 1 1
PMAIP1 UBE3A 0 0 157 156 1 1
PMAIP1 PPP1R13L 0 0 373 373 1 1
PMAIP1 HIST1H4C 0 0 167 167 1 1
PMAIP1 CAPN1 0 0 134 157 1 2
PMAIP1 AKT1 0 0 600 600 1 2
PMAIP1 RPL26 0 0 134 160 1 1
PMAIP1 ATF4 0 0 391 390 1 2
PMAIP1 CD4 0 0 294 294 1 2
PMAIP1 CA9 0 0 171 171 1 1
PMAIP1 FAS 0 0 560 560 1 2
PMAIP1 TLR9 0 0 123 242 1 2
PMAIP1 AIFM1 0 0 73 277 1 1
PMAIP1 MAP3K1 0 0 162 161 1 1
PMAIP1 CCNE2 0 0 202 252 1 1
PMAIP1 FANCD2 0 0 142 167 1 1
PMAIP1 FUBP1 0 0 143 166 1 1
PMAIP1 DENR 0 0 150 167 1 1
PMAIP1 BBC3 0 800 759 949 1 2
PMAIP1 ARFIP2 0 0 51 266 1 1
PMAIP1 IRF3 0 0 277 277 1 2
PMAIP1 ERBB2 0 0 414 414 1 2
PMAIP1 CD34 0 0 247 246 1 2
PMAIP1 NGF 0 0 155 154 1 2
PMAIP1 BIRC5 0 0 365 396 1 2
PMAIP1 SIRT4 0 0 181 185 1 1
PMAIP1 IL24 0 0 134 155 1 2
PMAIP1 PINK1 0 0 161 161 1 2
PMAIP1 BCL6 0 0 211 224 1 1
PMAIP1 PHGDH 0 0 155 154 1 1
PMAIP1 CCNG2 0 0 181 181 1 1
PMAIP1 ID2 0 0 167 167 1 1
PMAIP1 TYMS 0 0 124 166 1 1
PMAIP1 CXCL10 0 0 143 174 1 2
PMAIP1 BIRC8 0 0 252 283 1 1
PMAIP1 EIF4EBP1 0 0 310 338 1 2
PMAIP1 KRT18 0 0 142 195 1 1
PMAIP1 RNF7 270 0 370 520 1 1
PMAIP1 FEM1A 0 0 0 161 1 1
PMAIP1 FOXO4 0 0 275 275 1 1
PMAIP1 FEM1C 0 0 0 161 1 1
PMAIP1 CADM1 0 0 162 161 1 1
PMAIP1 VHL 0 0 146 158 1 2
PMAIP1 PSMB5 0 0 240 239 1 1
PMAIP1 LGALS3 0 0 125 165 1 2
PMAIP1 ALAS2 0 0 0 188 1 1
PMAIP1 DNAJB1 0 0 164 163 1 2
PMAIP1 ATG3 0 0 233 232 1 2
PMAIP1 BNIP1 0 0 170 188 1 2
PMAIP1 BIRC6 0 0 217 217 1 1
PMAIP1 CDKN3 0 0 451 477 1 1
PMAIP1 TLR3 0 0 194 194 1 2
PMAIP1 TP53INP1 0 0 294 294 1 2
PMAIP1 UBE2C 0 0 107 160 1 1
PMAIP1 FAM162A 0 0 203 203 1 1
PMAIP1 EIF2AK3 0 0 460 459 1 2
PMAIP1 POU4F1 0 0 125 156 1 1
PMAIP1 FOXO3 0 0 519 519 1 2
PMAIP1 VDAC3 0 0 208 208 1 1
PMAIP1 LYRM7 0 0 94 251 1 1
PMAIP1 SHISA5 0 0 316 385 1 1
PMAIP1 CDC42 0 0 141 174 1 2
PMAIP1 SRC 0 0 261 261 1 2
PMAIP1 GADD45G 0 0 224 240 1 1
PMAIP1 VDAC1 0 0 542 542 1 2
PMAIP1 TSC2 0 0 274 274 1 2
PMAIP1 PPM1D 0 0 392 392 1 1
PMAIP1 RBX1 0 0 261 261 1 1
PMAIP1 STAT5B 0 0 215 215 1 1
PMAIP1 BNIP3L 0 0 502 502 1 2
PMAIP1 CDKN1B 0 0 323 323 1 2
PMAIP1 PRKCD 0 0 193 193 1 2
PMAIP1 USP7 0 0 292 292 1 1
PMAIP1 RIPK3 0 0 241 257 1 2
PMAIP1 RB1 0 0 235 235 1 2
PMAIP1 TCHP 0 0 520 520 1 1
PMAIP1 HMOX1 0 0 251 257 1 2
PMAIP1 HIST1H4D 0 0 167 167 1 1
PMAIP1 SKP1 0 0 248 248 1 2
PMAIP1 EIF2S1 0 0 459 459 1 2
PMAIP1 RPL11 0 0 186 210 1 1
PMAIP1 UBA3 0 0 160 159 1 1
PMAIP1 RAC2 0 0 138 157 1 1
PMAIP1 TOMM20 0 0 175 175 1 2
PMAIP1 DYRK2 0 0 150 157 1 1
PMAIP1 COX4I1 0 0 391 390 1 1
PMAIP1 TP73 0 0 292 369 1 2
PMAIP1 HTRA2 0 0 504 504 1 1
PMAIP1 SOX2 0 0 181 181 1 2
PMAIP1 FBXW7 0 0 324 323 1 2
PMAIP1 HPGDS 0 0 156 155 1 1
PMAIP1 E2F7 0 0 171 259 1 1
PMAIP1 HIST2H2AA3 0 0 151 152 1 1
PMAIP1 HSP90AA1 0 0 404 404 1 2
PMAIP1 CTBP1 0 0 261 261 1 1
PMAIP1 FOSL1 0 0 123 170 1 1
PMAIP1 IL3 0 0 193 193 1 1
PMAIP1 TFDP1 0 900 65 904 1 1
PMAIP1 SQSTM1 0 0 271 271 1 2
PMAIP1 BNIP3 0 0 601 601 1 2
PMAIP1 HIST1H4J 0 0 167 167 1 1
PMAIP1 SIRT3 0 0 184 183 1 2
PMAIP1 PROM1 0 0 181 181 1 2
PMAIP1 MAPK3 0 0 364 368 1 2
PMAIP1 MMP9 0 0 233 232 1 2
PMAIP1 B2M 0 0 204 204 1 1
PMAIP1 KEAP1 0 0 251 250 1 2
PMAIP1 GTSE1 0 0 173 233 1 1
PMAIP1 DNMT1 0 0 205 205 1 2
PMAIP1 STUB1 0 0 228 227 1 2
PMAIP1 CD40 0 0 184 183 1 2
PMAIP1 HIST2H2AA 0 0 151 152 1 1
PMAIP1 ACTB 0 0 564 564 1 2
PMAIP1 ATG13 0 0 203 203 1 2
PMAIP1 INS 0 0 263 263 1 2
PMAIP1 CXCL12 0 0 157 156 1 2
PMAIP1 BAX 270 0 603 730 1 2
PMAIP1 AURKA 0 0 243 270 1 2
PMAIP1 AR 0 0 220 220 1 2
PMAIP1 PARP1 0 0 390 428 1 2
PMAIP1 TAF1B 0 0 291 290 1 1
PMAIP1 HSPA8 0 0 170 175 1 2
PMAIP1 BID 0 800 556 907 1 2
PMAIP1 GSR 0 0 159 158 1 1
PMAIP1 CDKN1A 0 0 652 664 1 2
PMAIP1 GABARAPL1 0 0 229 228 1 2
PMAIP1 PDK2 0 0 163 163 1 1
PMAIP1 ICAM1 0 0 151 150 1 2
PMAIP1 CCNB2 0 0 202 249 1 1
PMAIP1 ZEB1 0 0 164 163 1 2
PMAIP1 SIRT7 0 0 181 181 1 2
PMAIP1 BCL2L12 0 0 261 297 1 1
PMAIP1 PTPRC 0 0 243 275 1 1
PMAIP1 BCL10 0 0 173 173 1 1
PMAIP1 MLKL 0 0 205 205 1 2
PMAIP1 BMI1 0 0 323 327 1 1
PMAIP1 ARNT 0 0 215 215 1 2
PMAIP1 IL7R 0 0 137 163 1 1
PMAIP1 CDC25C 0 0 369 399 1 2
PMAIP1 APOL6 0 0 162 161 1 1
PMAIP1 SOD1 0 0 181 181 1 2
PMAIP1 UBE2F 0 0 322 321 1 1
PMAIP1 ZBTB38 0 0 74 229 1 1
PMAIP1 LCK 0 0 212 229 1 1
PMAIP1 LAMP2 0 0 143 159 1 2
PMAIP1 RIPK2 0 0 135 160 1 2
PMAIP1 SS18 0 0 82 200 1 1
PMAIP1 EI24 0 0 219 301 1 2
PMAIP1 MMP2 0 0 181 181 1 2
PMAIP1 RUNX3 0 0 159 159 1 1
PMAIP1 IGFBP3 0 0 284 296 1 2
PMAIP1 MFN1 0 0 211 211 1 2
PMAIP1 EIF2AK2 0 0 103 166 1 2
PMAIP1 RING1 0 0 181 181 1 1
PMAIP1 UCHL1 270 0 134 340 1 2
PMAIP1 CD8A 0 0 292 292 1 1
PMAIP1 CALR 0 0 187 187 1 1
PMAIP1 BIK 0 0 782 787 1 2
PMAIP1 TNFSF10 0 0 497 497 1 2
PMAIP1 SPATA18 0 0 138 192 1 1
PMAIP1 HSPA1A 0 0 259 263 1 1
PMAIP1 BOK 0 0 662 698 1 1
PMAIP1 PIK3CG 0 0 90 152 1 1
PMAIP1 CDC20 0 0 182 230 1 1
PMAIP1 CHEK1 0 0 470 498 1 2
PMAIP1 DNTT 0 0 324 323 1 1
PMAIP1 CASP1 0 0 286 297 1 2
PMAIP1 CCNA2 0 0 359 397 1 1
PMAIP1 ITPR3 0 0 174 173 1 1
PMAIP1 JUN 0 0 517 517 1 2
PMAIP1 DAPK1 0 0 242 241 1 2
PMAIP1 BCL2L11 417 800 872 984 1 2
PMAIP1 TRIM17 0 0 202 202 1 1
PMAIP1 ENSG00000173366 0 0 124 243 1 1
PMAIP1 HSP90B1 0 0 260 260 1 1
PMAIP1 RPTOR 0 0 181 181 1 2
PMAIP1 HSPB3 0 0 241 240 1 1
PMAIP1 NFYA 0 0 171 171 1 1
PMAIP1 IER3 0 0 204 223 1 1
PMAIP1 RAD17 0 0 158 157 1 1
PMAIP1 HSPA4 0 0 391 404 1 1
PMAIP1 LIF 0 0 89 182 1 2
PMAIP1 CSE1L 0 0 134 152 1 1
PMAIP1 CDKN1C 0 0 212 212 1 1
PMAIP1 DICER1 0 0 173 173 1 1
PMAIP1 SP4 0 0 0 153 1 1
PMAIP1 EGF 0 0 286 286 1 2
PMAIP1 PAWR 0 0 112 270 1 1
PMAIP1 SH3GLB1 0 0 193 193 1 2
PMAIP1 CDC6 0 0 119 183 1 1
PMAIP1 PCSK1 0 0 155 165 1 1
PMAIP1 ITPR1 0 0 188 188 1 2
PMAIP1 CASP9 0 0 710 713 1 2
PMAIP1 NANOG 0 0 232 231 1 2
PMAIP1 GFI1B 0 0 0 163 1 1
PMAIP1 SESN3 0 0 234 234 1 1
PMAIP1 TRAF6 0 0 182 181 1 2
PMAIP1 CHEK2 0 0 503 519 1 1
PMAIP1 RPS6KA3 0 0 210 210 1 1
PMAIP1 GADD45B 0 0 391 409 1 1
PMAIP1 DUSP12 0 0 180 179 1 1
PMAIP1 PLK2 0 0 261 295 1 1
PMAIP1 CYCS 0 0 765 765 1 2
PMAIP1 MAPK9 0 0 212 212 1 2
PMAIP1 IMMT 0 0 108 179 1 1
PMAIP1 MUT 0 0 150 165 1 1
PMAIP1 API5 0 0 0 189 1 1
PMAIP1 PHLDA1 0 0 72 172 1 1
PMAIP1 IGHV4-38-2 0 0 284 284 1 1
PMAIP1 MAPK8 0 0 391 390 1 2
PMAIP1 AURKB 0 0 197 244 1 1
PMAIP1 SKP2 0 0 244 243 1 2
PMAIP1 PRF1 0 0 154 153 1 1
PMAIP1 GPX4 0 0 124 178 1 2
PMAIP1 TNS1 0 0 162 161 1 1
PMAIP1 SESN2 0 0 402 402 1 2
PMAIP1 IFIH1 0 0 266 266 1 1
PMAIP1 DIABLO 0 0 681 681 1 2
PMAIP1 HIST2H3PS2 0 0 334 334 1 1
PMAIP1 H2AFX 0 0 390 406 1 1
PMAIP1 MAVS 0 0 234 234 1 2
PMAIP1 IL1A 0 0 96 159 1 1
PMAIP1 TRADD 0 0 391 390 1 1
PMAIP1 CUL5 461 0 167 531 1 1
PMAIP1 ALK 0 0 165 165 1 2
PMAIP1 XRCC4 0 0 120 157 1 1
PMAIP1 BCL2L13 0 0 284 284 1 2
PMAIP1 BUB1B 0 0 151 194 1 1
PMAIP1 IDH1 0 0 155 154 1 1
PMAIP1 NCF4 0 0 220 237 1 1
PMAIP1 CDH1 0 0 297 297 1 2
PMAIP1 BCL2L10 0 0 803 825 1 1
PMAIP1 HIST1H4E 0 0 167 167 1 1
PMAIP1 CDK6 0 0 335 335 1 2
PMAIP1 DDX58 0 0 358 358 1 1
PMAIP1 SIRT6 0 0 181 181 1 2
PMAIP1 BIRC3 0 0 465 473 1 1
PMAIP1 ANXA8 0 0 342 342 1 1
PMAIP1 TP53AIP1 0 0 681 681 1 1
PMAIP1 ERO1L 0 0 372 372 1 1
PMAIP1 ROCK1 0 0 113 168 1 2
PMAIP1 TNFRSF10A 0 0 565 565 1 1
PMAIP1 CDK5 0 0 259 258 1 2
PMAIP1 EP300 0 0 323 323 1 2
PMAIP1 PDGFRB 0 0 161 161 1 2
PMAIP1 CTNS 0 0 45 296 1 2
PMAIP1 CUL1 0 0 294 294 1 1
PMAIP1 CASP7 0 0 509 509 1 1
PMAIP1 SNAI2 0 0 195 195 1 1
PMAIP1 CASP8 0 0 682 701 1 2
PMAIP1 ALB 0 0 289 288 1 2
PMAIP1 CCL2 0 0 166 165 1 2
PMAIP1 SDHA 0 0 95 194 1 1
PMAIP1 EIF2AK4 0 0 209 209 1 2
PMAIP1 HMHA1 0 0 44 210 1 1
PMAIP1 VDAC2 0 0 324 323 1 1
PMAIP1 EZH2 0 0 261 302 1 2
PMAIP1 STAT3 0 0 391 390 1 2
PMAIP1 SIVA1 0 0 213 213 1 1
PMAIP1 ERN1 0 0 465 465 1 2
PMAIP1 XRCC6 0 0 289 288 1 1
PMAIP1 UACA 0 0 69 235 1 1
PMAIP1 RAD9A 0 0 193 193 1 1
PMAIP1 BRD4 0 0 174 173 1 2
PMAIP1 HUWE1 270 0 391 539 1 1
PMAIP1 CTBP2 0 0 170 169 1 1
PMAIP1 NR4A1 0 0 183 183 1 2
PMAIP1 JAK2 0 0 182 181 1 2
PMAIP1 HDAC6 0 0 261 261 1 2
PMAIP1 APAF1 0 0 728 728 1 2
PMAIP1 CDH2 0 0 162 161 1 1
PMAIP1 PSME3 0 0 95 157 1 1
PMAIP1 DDIT3 0 0 505 505 1 2
PMAIP1 HDAC2 0 0 253 252 1 1
PMAIP1 CRADD 0 0 233 232 1 1
PMAIP1 FAM96A 0 0 114 185 1 1
PMAIP1 RAF1 0 0 254 254 1 2
PMAIP1 LMNA 0 0 164 163 1 2
PMAIP1 EXO1 0 0 67 151 1 1
PMAIP1 C6orf222 0 0 180 179 1 1
PMAIP1 PRIMA1 0 0 325 325 1 1
PMAIP1 TRAF1 0 0 155 187 1 1
PMAIP1 HK2 0 0 182 211 1 2
PMAIP1 CUL2 0 0 164 163 1 1
PMAIP1 SLC2A1 0 0 234 234 1 2
PMAIP1 NEDD8 0 0 323 323 1 2
PMAIP1 FADD 0 0 518 519 1 2
PMAIP1 UCHL5 0 0 193 193 1 1
PMAIP1 MYD88 0 0 166 187 1 2
PMAIP1 HTT 0 0 135 150 1 2
PMAIP1 EGFR 0 0 405 405 1 2
PMAIP1 CFLAR 0 0 566 566 1 2
PMAIP1 CDK4 0 0 407 421 1 2
PMAIP1 HIST1H4I 0 0 167 188 1 1
PMAIP1 PRKCI 0 0 46 242 1 1
PMAIP1 TP53 0 900 806 983 1 2
PMAIP1 MDM2 0 0 710 714 1 2
PMAIP1 RAB2A 240 0 0 239 1 1
PMAIP1 AREG 0 0 103 189 1 1
PMAIP1 PHLDA3 0 0 234 234 1 1
PMAIP1 CHAC1 0 0 212 229 1 1
PMAIP1 STK11 0 0 214 214 1 2
PMAIP1 BRCA1 0 0 324 336 1 2
PMAIP1 CDKN2D 0 0 156 155 1 1
PMAIP1 PPIF 0 0 325 356 1 1
PMAIP1 MAP2K1 0 0 293 293 1 1
PMAIP1 ODC1 0 0 113 195 1 1
PMAIP1 RB1CC1 0 0 205 205 1 2
PMAIP1 NFE2L2 0 0 210 210 1 2
PMAIP1 PPP1R13B 0 0 338 338 1 1
PMAIP1 AKT2 0 0 175 175 1 2
PMAIP1 FAM96B 0 0 94 236 1 1
PMAIP1 CASP10 0 0 416 452 1 1
PMAIP1 NUPR1 0 0 185 185 1 2
PMAIP1 FLII 0 0 52 150 1 1
PMAIP1 NOXA1 0 0 325 329 1 1
PMAIP1 MOAP1 0 0 266 266 1 1
PMAIP1 SMAD4 0 0 202 202 1 2
PMAIP1 MYCN 270 0 293 461 1 1
PMAIP1 HIST1H4L 0 0 167 167 1 1
PMAIP1 PIK3CA 0 0 234 234 1 2
PMAIP1 TOP1 0 0 235 235 1 1
PMAIP1 MEN1 0 0 74 163 1 1
PMAIP1 TMBIM6 0 0 184 183 1 1
PMAIP1 P4HB 0 0 152 151 1 2
PMAIP1 TRAF2 0 0 213 243 1 2
PMAIP1 SDHC 0 0 244 243 1 1
PMAIP1 IGF1R 0 0 254 254 1 2
PMAIP1 MYC 0 0 720 738 1 2
PMAIP1 IL15 0 0 207 213 1 1
PMAIP1 IL18 0 0 157 156 1 2
PMAIP1 IFNA1 0 0 234 234 1 1
PMAIP1 PARK2 0 0 164 163 1 1
PMAIP1 DIRC2 0 0 156 155 1 1
PMAIP1 GABARAPL2 0 0 209 209 1 2
PMAIP1 MAP2K7 0 0 450 450 1 1
PMAIP1 HIST4H4 0 0 167 167 1 1
PMAIP1 NF1 0 0 161 161 1 1
PMAIP1 ABL1 0 0 324 323 1 1
PMAIP1 BNIPL 0 0 150 182 1 1
PMAIP1 TLR4 0 0 166 165 1 2
PMAIP1 GAPDH 0 0 556 556 1 2
PMAIP1 TNFRSF25 0 0 250 250 1 1
PMAIP1 ATG14 0 0 181 181 1 2
PMAIP1 KAT6A 0 0 128 178 1 1
PMAIP1 NFKB1 0 0 155 154 1 2
PMAIP1 KLF6 0 0 526 540 1 1
PMAIP1 TUBB4A 0 0 282 282 1 1
PMAIP1 BCL2L1 799 800 985 999 1 2
PMAIP1 RELA 0 0 337 337 1 2
PMAIP1 BUB1 0 0 101 175 1 1
PMAIP1 PIK3R4 0 0 195 195 1 2
PMAIP1 CASP6 0 0 590 590 1 1
PMAIP1 ZAP70 0 0 150 164 1 1
PMAIP1 SIRT2 0 0 218 218 1 2
PMAIP1 EPO 0 0 180 179 1 2
PMAIP1 ATF5 0 0 210 210 1 1
PMAIP1 SIAH1 0 0 206 206 1 1
PMAIP1 PLK1 0 0 261 296 1 2
PMAIP1 CCNB1 0 0 455 487 1 1
PMAIP1 ANXA5 0 0 650 650 1 2
PMAIP1 EFHD1 0 0 0 173 1 1
PMAIP1 PERP 0 0 651 653 1 1
PMAIP1 MGMT 0 0 203 203 1 2
PMAIP1 FOXM1 0 0 151 177 1 1
PMAIP1 DHX9 0 0 90 163 1 1
PMAIP1 HIST2H2AC 0 0 151 152 1 1
PMAIP1 BIRC2 0 0 468 476 1 1
PMAIP1 IFNG 0 0 158 179 1 2
PMAIP1 CREB1 0 0 310 309 1 2
PMAIP1 CCL5 0 0 125 156 1 2
PMAIP1 USP9X 0 0 459 459 1 1
PMAIP1 PPID 0 0 134 152 1 1
PMAIP1 FOXO6 0 0 228 227 1 1
PMAIP1 BCL2L2-PABPN1 0 0 818 838 1 1
PMAIP1 STAT1 0 0 253 252 1 2
PMAIP1 ENDOG 0 0 501 512 1 1
PMAIP1 RNASE1 0 0 54 198 1 1
PMAIP1 GZMB 0 0 194 194 1 1
PMAIP1 RPS6 0 0 142 173 1 2
PMAIP1 TNFRSF1A 0 0 392 392 1 1
PMAIP1 PIK3C3 0 0 295 295 1 2
PMAIP1 IL6 0 0 325 325 1 2
PMAIP1 CTRL 0 0 342 342 1 2
PMAIP1 RAD51 0 0 174 204 1 2
PMAIP1 MTOR 0 0 391 390 1 2
PMAIP1 POTEF 0 0 180 179 1 1
PMAIP1 E2F2 0 0 213 213 1 1
PMAIP1 HIST1H4F 0 0 167 167 1 1
PMAIP1 CXCR4 0 0 216 216 1 2
PMAIP1 PIDD1 0 0 558 568 1 1
PMAIP1 NOC2L 0 0 500 499 1 1
PMAIP1 TRAF4 0 0 122 168 1 1
PMAIP1 CD40LG 0 0 207 207 1 1
PMAIP1 SCO2 0 0 320 319 1 1
PMAIP1 NOTCH1 0 0 325 325 1 2
PMAIP1 ORC1 0 0 107 151 1 1
PMAIP1 XPO1 0 0 163 163 1 1
PMAIP1 SH2B2 0 0 0 151 1 1
PMAIP1 CDK2 0 0 451 480 1 2
PMAIP1 MAP1LC3A 0 0 141 194 1 2
PMAIP1 HRAS 0 0 421 422 1 2
PMAIP1 CTNNB1 0 0 340 340 1 2
PMAIP1 EGR1 0 0 244 257 1 2
PMAIP1 MFN2 0 0 235 235 1 2
PMAIP1 CXCL8 0 0 234 296 1 2
PMAIP1 ARF3 0 0 388 388 1 1
PMAIP1 SIRT5 0 0 171 171 1 1
PMAIP1 MT1E 0 0 344 343 1 1
PMAIP1 HIF1A 0 0 460 459 1 2
PMAIP1 BAG3 0 0 185 185 1 2
PMAIP1 IL1B 0 0 257 256 1 2
PMAIP1 NAE1 0 0 259 258 1 1
PMAIP1 CNBP 0 0 0 189 1 1
PMAIP1 SP1 0 0 204 218 1 2
Ontologies
ID Category Term Effect Evidence PubMed
GO:0005515 Molecular Function protein binding enables IPI
GO:0006974 Biological Process DNA damage response involved_in IEA
GO:0043029 Biological Process T cell homeostasis involved_in ISS
GO:0006915 Biological Process apoptotic process acts_upstream_of_or_within IMP
GO:0042149 Biological Process cellular response to glucose starvation involved_in IMP
GO:0071456 Biological Process cellular response to hypoxia involved_in IEP
GO:0051607 Biological Process defense response to virus involved_in IDA
GO:0097193 Biological Process intrinsic apoptotic signaling pathway involved_in IDA
GO:0072332 Biological Process intrinsic apoptotic signaling pathway by p53 class mediator involved_in IMP
GO:0010917 Biological Process negative regulation of mitochondrial membrane potential involved_in ISS
GO:0043517 Biological Process positive regulation of DNA damage response, signal transduction by p53 class mediator involved_in IMP
GO:0043065 Biological Process positive regulation of apoptotic process involved_in IDA
GO:0043065 Biological Process positive regulation of apoptotic process involved_in IMP
GO:0043280 Biological Process positive regulation of cysteine-type endopeptidase activity involved in apoptotic process involved_in IDA
GO:1902237 Biological Process positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway involved_in TAS
GO:1902043 Biological Process positive regulation of extrinsic apoptotic signaling pathway via death domain receptors involved_in IDA
GO:0010907 Biological Process positive regulation of glucose metabolic process involved_in IDA
GO:2001244 Biological Process positive regulation of intrinsic apoptotic signaling pathway involved_in IDA
GO:0090200 Biological Process positive regulation of release of cytochrome c from mitochondria involved_in IDA
GO:0090200 Biological Process positive regulation of release of cytochrome c from mitochondria involved_in IMP
GO:0010498 Biological Process proteasomal protein catabolic process involved_in IDA
GO:0072593 Biological Process reactive oxygen species metabolic process involved_in IDA
GO:0046902 Biological Process regulation of mitochondrial membrane permeability involved_in IDA
GO:0001836 Biological Process release of cytochrome c from mitochondria involved_in IEA
GO:0043331 Biological Process response to dsRNA involved_in IDA
GO:0097136 Cellular Component Bcl-2 family protein complex part_of IPI
GO:0005829 Cellular Component cytosol located_in IDA
GO:0005829 Cellular Component cytosol located_in TAS
GO:0005741 Cellular Component mitochondrial outer membrane located_in TAS
GO:0005739 Cellular Component mitochondrion is_active_in IBA
GO:0005739 Cellular Component mitochondrion located_in IDA
GO:0005634 Cellular Component nucleus located_in IDA
Pathways
Name DB ID
Apoptosis Reactome R-HSA-109581
Intrinsic Pathway for Apoptosis Reactome R-HSA-109606
Activation of NOXA and translocation to mitochondria Reactome R-HSA-111448
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members Reactome R-HSA-111453
Activation of BH3-only proteins Reactome R-HSA-114452
Generic Transcription Pathway Reactome R-HSA-212436
Transcriptional Regulation by TP53 Reactome R-HSA-3700989
Programmed Cell Death Reactome R-HSA-5357801
TP53 Regulates Transcription of Cell Death Genes Reactome R-HSA-5633008
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release Reactome R-HSA-6803204
RNA Polymerase II Transcription Reactome R-HSA-73857
Gene expression (Transcription) Reactome R-HSA-74160
Photodynamic therapy-induced HIF-1 survival signaling (WP3614) WikiPathways WP3614_r106542
p53 transcriptional gene network (WP4963) WikiPathways WP4963_r122690
Chromosomal and microsatellite instability in colorectal cancer (WP4216) WikiPathways WP4216_r123363
miRNA regulation of p53 pathway in prostate cancer (WP3982) WikiPathways WP3982_r108115
DNA damage response (only ATM dependent) (WP710) WikiPathways WP710_r116542
Unfolded protein response (WP4925) WikiPathways WP4925_r123438
DNA damage response (WP707) WikiPathways WP707_r124174
TP53 network (WP1742) WikiPathways WP1742_r116592
Apoptosis (WP254) WikiPathways WP254_r118382
H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity (WP3969) WikiPathways WP3969_r123402
Apoptosis modulation and signaling (WP1772) WikiPathways WP1772_r120736
miRNA regulation of DNA damage response (WP1530) WikiPathways WP1530_r124175
Transcripts
Accession Version MolecularType Name NCBI Comments
NM_001382617 1 mRNA transcript variant 3 NC_000018 Reference
NM_001382623 1 mRNA transcript variant 4 NC_000018 Reference
NM_001382616 1 mRNA transcript variant 1 NC_000018 Reference
NM_001382618 1 mRNA transcript variant 2 NC_000018 Reference
NM_001382615 1 mRNA transcript variant 5 NC_000018 Reference
NM_021127 3 mRNA transcript variant 6 NC_000018 Reference