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TET2

tet methylcytosine dioxygenase 2
General Information
Name tet methylcytosine dioxygenase 2
Alias
  • methylcytosine dioxygenase TET2
  • probable methylcytosine dioxygenase TET2
  • ten-eleven translocation 2
  • tet oncogene family member 2
Gene_family Tet methylcytosine dioxygenase family
organism Homo sapiens
entrez_id 54790
location 4q24
transcript_count 13
exon_count 14
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders. Two variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
    Stringdb Methylcytosine dioxygenase TET2; Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5- hydroxymethylcytosine (5hmC) and plays a key role in active DNA demethylation. Has a preference for 5-hydroxymethylcytosine in CpG motifs. Also mediates subsequent conversion of 5hmC into 5- formylcytosine (5fC), and conversion of 5fC to 5-carboxylcytosine (5caC). Conversion of 5mC into 5hmC, 5fC and 5caC probably constitutes the first step in cytosine demethylation. Methylation at the C5 position of cytosine bases is an epigenetic modification of the m [...]
    nextProt Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in active DNA demethylation. Has a preference for 5-hydroxymethylcytosine in CpG motifs. Also mediates subsequent conversion of 5hmC into 5-formylcytosine (5fC), and conversion of 5fC to 5-carboxylcytosine (5caC). Conversion of 5mC into 5hmC, 5fC and 5caC probably constitutes the first step in cytosine demethylation. Methylation at the C5 position of cytosine bases is an epigenetic modification of the mammalian genome which plays an important role in transcriptional regulation. In addition to its role in DNA demethylation, also involved in the recruitment of the O-GlcNAc transferase OGT to CpG-rich transcription start sites of active genes, thereby promoting histone H2B GlcNAcylation by OGT.
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
TET2 BioGRID S GeneID BioGRID Proximity Label-MS
TET2 BioGRID S GeneID BioGRID Proximity Label-MS
TET2 BioGRID ACE2 GeneID BioGRID Proximity Label-MS
TET2 BioGRID TLE3 GeneID BioGRID Proximity Label-MS
TET2 BioGRID YWHAQ GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
TET2 BioGRID SFN GeneID BioGRID Proximity Label-MS
TET2 BioGRID YWHAZ GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
TET2 BioGRID YWHAH GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
TET2 BioGRID YWHAG GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
TET2 BioGRID YWHAE GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
TET2 BioGRID TIPARP GeneID BioGRID Affinity Capture-MS
TET2 BioGRID RNF113A GeneID BioGRID Co-fractionation
TET2 BioGRID LATS1 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID PRMT1 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID PSPC1 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID YWHAB GeneID BioGRID Affinity Capture-MS
TET2 BioGRID AR GeneID BioGRID Proximity Label-MS
TET2 BioGRID NFIC GeneID BioGRID Proximity Label-MS
TET2 BioGRID ERG GeneID BioGRID Proximity Label-MS
TET2 BioGRID KLF5 GeneID BioGRID Proximity Label-MS
TET2 BioGRID MBD3 GeneID BioGRID Affinity Capture-Western
TET2 BioGRID TLX3 GeneID BioGRID Proximity Label-MS
TET2 BioGRID TBR1 GeneID BioGRID Proximity Label-MS
TET2 BioGRID GCM1 GeneID BioGRID Proximity Label-MS
TET2 BioGRID PAX8 GeneID BioGRID Proximity Label-MS
TET2 BioGRID HNF1B GeneID BioGRID Proximity Label-MS
TET2 BioGRID SOX2 GeneID BioGRID Proximity Label-MS
TET2 BioGRID SP7 GeneID BioGRID Proximity Label-MS
TET2 BioGRID NUP62CL GeneID BioGRID Affinity Capture-MS
TET2 BioGRID SEMG1 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID NONO GeneID BioGRID Affinity Capture-MS
TET2 BioGRID WDR5 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
TET2 BioGRID VHL GeneID BioGRID Affinity Capture-Western
TET2 BioGRID TP53 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID EGLN3 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
TET2 BioGRID EGLN1 GeneID BioGRID Affinity Capture-Western
TET2 BioGRID NIPBL GeneID BioGRID Affinity Capture-MS
TET2 BioGRID MAU2 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID SNIP1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-localization; Reconstituted Complex; Two-hybrid
TET2 BioGRID ZCCHC14 GeneID BioGRID Affinity Capture-Western; Two-hybrid
TET2 BioGRID TFEC GeneID BioGRID Affinity Capture-Western; Two-hybrid
TET2 BioGRID ECD GeneID BioGRID Affinity Capture-Western; Two-hybrid
TET2 BioGRID RAI1 GeneID BioGRID Affinity Capture-Western; Two-hybrid
TET2 BioGRID KEAP1 GeneID BioGRID Affinity Capture-Western; Two-hybrid
TET2 BioGRID BCLAF1 GeneID BioGRID Affinity Capture-Western
TET2 BioGRID EIF2B2 GeneID BioGRID Affinity Capture-Western; Two-hybrid
TET2 BioGRID OGT GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Two-hybrid
TET2 BioGRID ZNF207 GeneID BioGRID Affinity Capture-Western; Two-hybrid
TET2 BioGRID VPS72 GeneID BioGRID Affinity Capture-Western; Two-hybrid
TET2 BioGRID STAT5A GeneID BioGRID Affinity Capture-Western; Two-hybrid
TET2 BioGRID MED1 GeneID BioGRID Affinity Capture-Western; Two-hybrid
TET2 BioGRID PKNOX1 GeneID BioGRID Affinity Capture-Western; Two-hybrid
TET2 BioGRID MYC GeneID BioGRID Affinity Capture-Western
TET2 BioGRID MNAT1 GeneID BioGRID Affinity Capture-Western; Two-hybrid
TET2 BioGRID SMAD1 GeneID BioGRID Affinity Capture-Western; Two-hybrid
TET2 BioGRID HOXB9 GeneID BioGRID Affinity Capture-Western; Two-hybrid
TET2 BioGRID HLF GeneID BioGRID Affinity Capture-Western; Two-hybrid
TET2 BioGRID PHC1 GeneID BioGRID Affinity Capture-Western; Two-hybrid
TET2 BioGRID CDC5L GeneID BioGRID Affinity Capture-Western
TET2 BioGRID TUBB GeneID BioGRID Affinity Capture-MS
TET2 BioGRID DCD GeneID BioGRID Affinity Capture-MS
TET2 BioGRID BPIFB1 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID MYH14 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID CALML5 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID BPIFA1 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID PABPC1 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID SUB1 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID MYL12A GeneID BioGRID Affinity Capture-MS
TET2 BioGRID MYL9 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID TUBA1B GeneID BioGRID Affinity Capture-MS
TET2 BioGRID LANCL1 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID BCAR1 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID CUL2 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID BCAR3 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID H2BC4 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID TAF15 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID VIM GeneID BioGRID Affinity Capture-MS
TET2 BioGRID TPM3 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID TPM2 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID TPM1 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID TF GeneID BioGRID Affinity Capture-MS
TET2 BioGRID ELOB GeneID BioGRID Affinity Capture-MS
TET2 BioGRID ELOC GeneID BioGRID Affinity Capture-MS
TET2 BioGRID TRIM21 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID RPS18 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID PML GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-localization
TET2 BioGRID PLEC GeneID BioGRID Affinity Capture-MS
TET2 BioGRID PCMT1 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID PRDX1 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID MYL6 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID MYH10 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID MYH9 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID LYZ GeneID BioGRID Affinity Capture-MS
TET2 BioGRID LTF GeneID BioGRID Affinity Capture-MS
TET2 BioGRID LDHA GeneID BioGRID Affinity Capture-MS
TET2 BioGRID IGHG2 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID HSPD1 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID HSP90AB1 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID HSPA9 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID HSPA8 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID HSPA6 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID HSPA1L GeneID BioGRID Affinity Capture-MS
TET2 BioGRID HSPA1A GeneID BioGRID Affinity Capture-MS
TET2 BioGRID HNRNPH1 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID GRN GeneID BioGRID Affinity Capture-MS
TET2 BioGRID GAPDH GeneID BioGRID Affinity Capture-MS
TET2 BioGRID FGB GeneID BioGRID Affinity Capture-MS
TET2 BioGRID ENO1 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID EEF1A1 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID DNMT3A GeneID BioGRID Affinity Capture-Western
TET2 BioGRID DDX3X GeneID BioGRID Affinity Capture-MS
TET2 BioGRID CLTC GeneID BioGRID Affinity Capture-MS
TET2 BioGRID CLTA GeneID BioGRID Affinity Capture-MS
TET2 BioGRID AZGP1 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID ARF1 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID APOA1 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID ANXA2 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID SLC25A6 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID ALB GeneID BioGRID Affinity Capture-MS
TET2 BioGRID ACTB GeneID BioGRID Affinity Capture-MS
TET2 BioGRID ACTA1 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID VIRMA GeneID BioGRID Affinity Capture-RNA
TET2 BioGRID RNF31 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID EBF1 GeneID BioGRID Affinity Capture-Western
TET2 BioGRID DCAF1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
TET2 BioGRID DDB1 GeneID BioGRID Affinity Capture-Western
TET2 BioGRID PAN2 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID TCF3 GeneID BioGRID Affinity Capture-MS
TET2 BioGRID TBC1D4 GeneID BioGRID Two-hybrid
StringDB
A B experiments database textmining combined score hadb nhadb
TET2 PALB2 0 0 164 163 1 1
TET2 MYSM1 0 0 73 324 1 1
TET2 IL3RA 0 0 288 288 1 1
TET2 MPO 0 0 241 240 1 2
TET2 CXXC1 0 0 234 546 1 1
TET2 BRMS1L 0 0 0 201 1 1
TET2 PIK3C3 0 0 0 221 1 2
TET2 LYZ 270 0 47 288 1 1
TET2 GNA13 0 0 112 151 1 1
TET2 IL6 0 0 339 343 1 2
TET2 NFYB 0 0 95 151 1 1
TET2 BRD2 0 0 211 216 1 1
TET2 STAT1 0 0 211 211 1 2
TET2 H3F3A 0 0 293 318 1 1
TET2 CXXC4 0 0 984 987 1 1
TET2 CD177 0 0 327 327 1 1
TET2 LXN 0 0 270 270 1 1
TET2 YLPM1 0 0 57 249 1 1
TET2 RRAS 0 0 143 166 1 1
TET2 HIST1H4F 0 0 219 219 1 1
TET2 CXCR4 0 0 193 193 1 2
TET2 NOTCH1 0 0 468 468 1 2
TET2 ARAF 0 0 142 174 1 1
TET2 KAT6B 0 0 141 235 1 1
TET2 MTOR 0 0 202 220 1 2
TET2 SMARCAD1 0 0 122 232 1 1
TET2 TRIM59 0 0 73 217 1 1
TET2 BCAR3 270 0 0 270 1 1
TET2 ANXA11 0 0 0 167 1 1
TET2 POTEF 0 0 156 170 1 1
TET2 JARID2 0 0 342 357 1 1
TET2 ADAR 0 0 136 268 1 1
TET2 TSHZ1 0 0 0 205 1 1
TET2 CTNNB1 0 0 341 341 1 2
TET2 MSH6 0 0 254 292 1 1
TET2 HRAS 0 0 684 684 1 2
TET2 ASPA 0 0 0 205 1 1
TET2 EGR1 0 0 194 224 1 2
TET2 APOBEC3B 0 0 161 192 1 1
TET2 DDR2 0 0 134 168 1 1
TET2 XPO1 0 0 203 208 1 1
TET2 PHC1 270 0 57 317 1 1
TET2 HIF1A 0 0 391 390 1 2
TET2 SIRT5 0 0 207 207 1 1
TET2 PRRC2A 0 0 0 197 1 1
TET2 SP1 0 0 124 179 1 2
TET2 ZMYM3 0 0 208 225 1 1
TET2 FAT1 0 0 309 309 1 1
TET2 IL1B 0 0 250 250 1 2
TET2 KIAA1429 270 0 53 294 1 1
TET2 CXCL8 0 0 161 161 1 2
TET2 LEFTY1 0 0 252 267 1 1
TET2 PML 270 0 70 292 1 2
TET2 IL9R 0 0 54 504 1 1
TET2 TOPORS 0 0 46 605 1 1
TET2 ENO1 270 0 63 286 1 1
TET2 SH2B3 0 0 650 650 1 1
TET2 FGFR2 0 0 233 232 1 1
TET2 APOBEC2 0 0 167 254 1 1
TET2 GAPDH 270 0 390 536 1 2
TET2 SMG1 0 0 0 165 1 1
TET2 UTF1 0 0 242 253 1 1
TET2 RPS6KA5 0 0 81 169 1 1
TET2 ATRX 0 0 401 451 1 1
TET2 APOA1 270 0 0 270 1 1
TET2 ABL1 0 0 561 561 1 1
TET2 CSMD1 0 0 181 181 1 1
TET2 HIST4H4 0 0 219 219 1 1
TET2 NF1 0 0 519 531 1 1
TET2 EBF1 270 0 897 922 1 1
TET2 ELF1 0 0 66 160 1 1
TET2 MAP2K7 0 0 256 256 1 1
TET2 KITLG 0 0 233 232 1 1
TET2 ELF5 0 0 154 153 1 1
TET2 HOXB9 270 0 81 300 1 1
TET2 PCLO 0 0 54 419 1 1
TET2 SF3A1 0 0 323 323 1 1
TET2 CD7 0 0 275 275 1 1
TET2 TNRC6B 0 0 118 158 1 1
TET2 UHRF1 0 0 561 595 1 1
TET2 DNMT3A 270 0 874 915 1 2
TET2 XPA 0 0 53 155 1 1
TET2 DNMT3B 0 0 839 859 1 1
TET2 KAT6A 0 0 281 337 1 1
TET2 RELA 0 0 260 262 1 2
TET2 BCL2L1 0 0 219 219 1 2
TET2 AOC3 0 0 101 157 1 1
TET2 CARM1 0 0 148 210 1 2
TET2 KMT2E 0 0 242 307 1 1
TET2 PRRC2B 0 0 96 234 1 1
TET2 ANXA5 0 0 218 231 1 2
TET2 NPM2 0 0 150 188 1 1
TET2 FTO 0 0 368 368 1 2
TET2 WHSC1 0 0 235 251 1 1
TET2 SLC25A6 270 0 0 383 1 1
TET2 HOXA7 0 0 181 181 1 1
TET2 POLR2A 0 0 90 283 1 1
TET2 MGMT 0 0 260 260 1 2
TET2 HSPD1 270 0 0 270 1 1
TET2 MBD1 0 0 183 216 1 1
TET2 SIRT2 0 0 243 249 1 2
TET2 U2AF1L4 0 0 770 771 1 1
TET2 TTC4 0 0 180 179 1 1
TET2 FAM13A 0 0 261 277 1 1
TET2 RELN 0 0 166 172 1 1
TET2 PLEC 270 0 0 278 1 1
TET2 EPO 0 0 347 347 1 2
TET2 SDHB 0 0 154 201 1 1
TET2 BCL11B 0 0 193 212 1 1
TET2 NFE2 0 0 184 183 1 1
TET2 RUNX1T1 0 0 560 560 1 1
TET2 TNP1 0 0 48 172 1 1
TET2 ARF1 270 0 0 270 1 1
TET2 JHDM3C 0 0 325 357 1 1
TET2 HSPA1L 270 0 0 270 1 1
TET2 POU3F2 0 0 124 159 1 1
TET2 TAF15 270 0 0 270 1 1
TET2 CREBBP 0 0 455 467 1 1
TET2 C10orf35 0 0 107 154 1 1
TET2 IFNG 0 0 137 190 1 2
TET2 HIST2H2AC 0 0 341 341 1 1
TET2 ELOVL2 0 0 61 227 1 1
TET2 CREB1 0 0 206 223 1 2
TET2 STAG2 0 0 651 659 1 1
TET2 TWSG1 0 0 235 235 1 1
TET2 PAK7 0 0 91 191 1 1
TET2 MYL9 270 0 0 270 1 1
TET2 BACH2 0 0 134 153 1 1
TET2 NFE2L2 0 0 163 163 1 2
TET2 EHMT2 0 0 435 439 1 2
TET2 CDC5L 270 0 0 270 1 1
TET2 MECP2 0 0 504 554 1 1
TET2 TDGF1 0 0 126 154 1 1
TET2 MBD2 0 0 183 203 1 1
TET2 ZNF423 0 0 69 151 1 1
TET2 GRSF1 0 0 0 250 1 1
TET2 BRCA1 0 0 341 341 1 2
TET2 STK11 0 0 266 266 1 2
TET2 BRD9 0 0 156 170 1 1
TET2 TCF3 270 0 335 493 1 1
TET2 IKZF3 0 0 155 188 1 1
TET2 VPS72 270 0 0 270 1 1
TET2 FUT4 0 0 283 282 1 1
TET2 MAP2K1 0 0 170 169 1 1
TET2 DNHD1 0 0 108 153 1 1
TET2 HDAC3 0 0 107 191 1 2
TET2 HIST1H4L 0 0 219 219 1 1
TET2 SMAD4 0 0 260 260 1 2
TET2 MYCN 0 0 218 218 1 1
TET2 TFEC 270 0 0 289 1 1
TET2 LRP1B 0 0 162 246 1 1
TET2 HOXB3 0 0 134 157 1 1
TET2 HDAC5 0 0 137 221 1 1
TET2 DPPA5 0 0 141 217 1 1
TET2 TCL1B 0 0 288 288 1 1
TET2 ZNF501 0 0 166 179 1 1
TET2 ACTA1 270 0 0 278 1 1
TET2 ZFP57 0 0 265 289 1 1
TET2 ANXA9 0 0 0 189 1 1
TET2 GLS 0 0 118 152 1 2
TET2 MX1 0 0 232 238 1 1
TET2 MEN1 0 0 218 218 1 1
TET2 YTHDF2 0 0 142 195 1 1
TET2 GNAQ 0 0 139 157 1 1
TET2 DVL1 0 0 134 157 1 1
TET2 MYH10 270 0 46 273 1 1
TET2 GSTCD 0 0 212 212 1 1
TET2 EGLN3 0 0 181 232 1 1
TET2 CAMKMT 0 0 181 215 1 1
TET2 PIK3CA 0 0 336 350 1 2
TET2 IL2RA 0 0 167 167 1 1
TET2 CLTA 270 0 0 270 1 1
TET2 APEX1 0 0 215 219 1 1
TET2 ZBED6 0 0 0 579 1 1
TET2 MYC 270 0 504 622 1 2
TET2 DCD 270 0 0 270 1 1
TET2 IFNA1 0 0 195 195 1 1
TET2 CBX5 0 0 174 186 1 1
TET2 HOXA9 0 0 420 434 1 1
TET2 ROBO4 0 0 68 275 1 1
TET2 SDHC 0 0 169 183 1 1
TET2 COL11A1 0 0 53 284 1 1
TET2 PPARGC1A 0 0 140 159 1 2
TET2 HLTF 0 0 134 383 1 1
TET2 H1F0 0 0 203 203 1 1
TET2 RASAL1 0 0 150 223 1 1
TET2 MTAP 0 0 103 568 1 1
TET2 NF2 0 0 210 210 1 1
TET2 GATA3 0 0 294 294 1 1
TET2 HOXD13 0 0 124 154 1 1
TET2 RBBP6 0 0 84 255 1 1
TET2 AGO2 0 0 203 203 1 2
TET2 POU5F1B 0 0 0 206 1 1
TET2 STAT3 0 0 395 408 1 2
TET2 ETNK1 0 0 400 413 1 1
TET2 EZH2 0 0 789 798 1 2
TET2 DDAH2 0 0 57 151 1 1
TET2 JAK2 0 0 739 751 1 2
TET2 HDAC6 0 0 433 451 1 2
TET2 KDM7A 0 0 203 336 1 1
TET2 AFF1 0 0 228 227 1 1
TET2 BRD4 0 0 391 408 1 2
TET2 BAZ2A 0 0 67 184 1 1
TET2 ALKBH3 0 0 241 257 1 1
TET2 NCOR2 0 0 193 225 1 1
TET2 PTPRD 0 0 151 157 1 1
TET2 CSF3 0 0 285 284 1 1
TET2 FAM135B 0 0 235 251 1 1
TET2 CUL2 270 0 0 270 1 1
TET2 HDAC2 0 0 987 989 1 1
TET2 RNMT 0 0 210 210 1 1
TET2 HNRNPA1L2 0 0 0 156 1 1
TET2 MYL6 270 0 0 270 1 1
TET2 ZNF44 0 0 166 179 1 1
TET2 DAZL 0 0 218 257 1 1
TET2 TMEM92 0 0 60 205 1 1
TET2 PABPC1 270 0 0 270 1 1
TET2 NFKBIZ 0 0 891 893 1 1
TET2 ASPH 0 0 88 224 1 1
TET2 RHOXF2 0 0 103 165 1 1
TET2 TP53 0 0 681 681 1 2
TET2 MDM2 0 0 294 294 1 2
TET2 MYH14 270 0 0 270 1 1
TET2 MSL3 0 0 0 188 1 1
TET2 COL5A2 0 0 0 160 1 1
TET2 FGFR3 47 0 218 222 1 1
TET2 DCUN1D1 0 0 156 163 1 1
TET2 SLC2A1 0 0 170 170 1 2
TET2 EGFR 0 0 325 339 1 2
TET2 CDK4 0 0 209 209 1 2
TET2 KANK1 0 0 75 167 1 1
TET2 HIST1H4I 0 0 219 219 1 1
TET2 MYD88 0 0 286 286 1 2
TET2 GATA1 0 0 603 603 1 1
TET2 ALKBH2 0 0 246 262 1 1
TET2 H3F3B 0 0 294 319 1 1
TET2 ENSG00000280267 0 0 165 165 1 1
TET2 RBM19 0 0 161 161 1 1
TET2 KLHL1 0 0 90 152 1 1
TET2 APOBEC1 0 0 324 340 1 1
TET2 LGALS4 0 0 454 454 1 1
TET2 MAF 0 0 171 171 1 1
TET2 PRIMPOL 0 0 0 254 1 1
TET2 ECD 270 0 0 270 1 2
TET2 CUX1 0 0 367 367 1 1
TET2 KLHL6 0 0 170 190 1 1
TET2 ASXL3 0 0 282 297 1 1
TET2 ALK 0 0 310 309 1 2
TET2 PAX6 0 0 215 215 1 1
TET2 TSEN54 0 0 134 153 1 1
TET2 SUZ12 0 0 517 527 1 1
TET2 YWHAG 270 0 0 270 1 1
TET2 HIST1H4E 0 0 219 219 1 1
TET2 HLF 270 0 45 273 1 1
TET2 SIRT6 0 0 266 266 1 2
TET2 DDX41 0 0 325 325 1 1
TET2 HDAC8 0 0 181 233 1 1
TET2 ANKRD11 0 0 182 199 1 1
TET2 KMT2B 0 0 467 497 1 1
TET2 CDK6 0 0 234 234 1 2
TET2 GLIS2 0 0 163 176 1 1
TET2 ZCCHC14 270 0 0 271 1 1
TET2 ZNF763 0 0 166 179 1 1
TET2 TRIM21 270 0 0 270 1 1
TET2 PDGFRA 0 0 406 406 1 1
TET2 ZEB2 0 0 206 229 1 1
TET2 CDH1 0 0 218 218 1 2
TET2 IDH1 0 0 859 868 1 1
TET2 MORF4L2 0 0 0 188 1 1
TET2 CD33 0 0 400 400 1 1
TET2 LEF1 0 0 170 169 1 1
TET2 LIG3 0 0 48 167 1 1
TET2 PDGFRB 0 0 320 319 1 2
TET2 SRP72 0 0 202 202 1 1
TET2 EP300 0 0 460 474 1 2
TET2 CHD1 0 0 209 226 1 1
TET2 NOTCH3 0 0 162 161 1 1
TET2 MLLT10 0 0 286 319 1 1
TET2 IL4 0 0 193 193 1 1
TET2 ANKRD55 0 0 195 195 1 1
TET2 HCFC1 270 0 408 558 1 1
TET2 SMAD3 0 0 454 454 1 2
TET2 MLLT4 0 0 143 166 1 1
TET2 PKNOX1 270 0 0 270 1 1
TET2 CALML5 270 0 0 270 1 1
TET2 EME2 0 0 94 219 1 1
TET2 SDHA 0 0 203 203 1 1
TET2 ALB 270 0 194 399 1 2
TET2 SNX32 0 0 84 216 1 1
TET2 CASP8 0 0 117 167 1 2
TET2 ZNF436 0 0 168 181 1 1
TET2 ANXA3 0 0 0 188 1 1
TET2 KAT2A 0 0 218 235 1 1
TET2 CUL1 0 0 397 396 1 1
TET2 MME 0 0 218 218 1 1
TET2 PIWIL4 0 0 202 216 1 1
TET2 SMARCA2 0 0 231 248 1 1
TET2 LTF 270 0 0 270 1 1
TET2 GATA4 0 0 233 232 1 2
TET2 LIF 0 0 234 240 1 2
TET2 SNRPN 0 0 171 181 1 1
TET2 CDKN1C 0 0 155 154 1 1
TET2 DICER1 0 0 218 253 1 1
TET2 PIK3R1 0 0 210 228 1 1
TET2 CLTC 270 0 44 289 1 1
TET2 BPTF 0 0 46 239 1 1
TET2 SERINC5 0 0 120 175 1 1
TET2 PDCD4 0 0 74 217 1 2
TET2 NES 0 0 208 208 1 2
TET2 CLEC12A 0 0 123 155 1 1
TET2 XPO5 0 0 76 228 1 1
TET2 HIST3H2A 0 0 0 215 1 1
TET2 TEK 0 0 68 170 1 1
TET2 GNAS 0 0 393 392 1 1
TET2 LUC7L2 0 0 390 406 1 1
TET2 PPARA 0 0 497 497 1 2
TET2 GFI1B 0 0 217 229 1 1
TET2 NANOG 0 0 984 987 1 2
TET2 MYL12A 270 0 0 270 1 1
TET2 OGG1 0 0 142 185 1 1
TET2 YIPF6 0 0 60 156 1 1
TET2 CHEK2 0 0 261 261 1 1
TET2 GADD45B 0 0 306 323 1 1
TET2 FIP1L1 0 0 320 334 1 1
TET2 PAN2 0 0 0 163 1 1
TET2 SETD7 0 0 193 210 1 1
TET2 SMARCA5 0 0 204 204 1 1
TET2 IL17A 0 0 418 418 1 2
TET2 SBDS 0 0 203 203 1 1
TET2 ETS1 0 0 142 275 1 1
TET2 XRCC1 0 0 123 215 1 1
TET2 IGHV4-38-2 0 0 320 319 1 1
TET2 BCL11A 0 0 122 168 1 1
TET2 VIM 270 0 74 295 1 2
TET2 CBFA2T3 0 0 248 248 1 1
TET2 ZNF217 0 0 161 192 1 1
TET2 AURKB 0 0 108 158 1 1
TET2 MUT 0 0 155 161 1 1
TET2 CD79B 0 0 159 158 1 1
TET2 FOXP1 0 0 134 189 1 1
TET2 TBX3 0 0 249 258 1 1
TET2 STOX2 0 0 92 175 1 1
TET2 MEST 0 0 181 212 1 1
TET2 KLF5 0 0 170 182 1 2
TET2 SCIN 0 0 0 202 1 1
TET2 HSPA6 270 0 0 270 1 1
TET2 VEZF1 0 0 49 291 1 1
TET2 HIST2H3PS2 0 0 507 507 1 1
TET2 TPM2 270 0 0 270 1 1
TET2 KDM2A 0 0 350 380 1 1
TET2 HNRNPA2B1 0 0 49 164 1 1
TET2 BPIFA1 270 0 0 270 1 1
TET2 HNMT 0 0 264 264 1 1
TET2 H2AFZ 0 0 208 208 1 1
TET2 SMARCB1 0 0 236 236 1 1
TET2 ALKBH4 0 0 123 234 1 1
TET2 BPIFB1 270 0 0 270 1 1
TET2 NR3C1 0 0 181 201 1 1
TET2 KDM4A 0 0 390 403 1 1
TET2 ELP3 0 0 96 234 1 1
TET2 TET3 0 600 910 802 1 1
TET2 GRN 270 0 0 303 1 1
TET2 ZBTB38 0 0 218 255 1 1
TET2 PHC2 0 0 0 166 1 1
TET2 AZGP1 270 0 0 270 1 1
TET2 NEIL1 0 0 234 531 1 1
TET2 SPOP 0 0 150 182 1 1
TET2 YWHAE 270 0 0 270 1 1
TET2 LCK 0 0 358 362 1 1
TET2 MED12 0 0 219 236 1 1
TET2 TBC1D4 192 0 0 192 1 1
TET2 TEX10 0 0 430 444 1 1
TET2 ARNT 0 0 127 167 1 2
TET2 IL7R 0 0 218 218 1 1
TET2 BMI1 0 0 295 296 1 1
TET2 SMC3 0 0 506 516 1 1
TET2 SMC1A 0 0 518 543 1 1
TET2 DUSP22 0 0 205 205 1 1
TET2 SOX17 0 0 195 212 1 1
TET2 CSNK1A1 0 0 181 181 1 1
TET2 PRDX1 270 0 0 270 1 1
TET2 HAVCR2 0 0 170 169 1 1
TET2 ARID1B 0 0 254 280 1 1
TET2 FANCA 0 0 170 210 1 1
TET2 SMAD1 270 0 46 273 1 2
TET2 CALR 0 0 601 601 1 1
TET2 MNAT1 270 0 0 270 1 1
TET2 CD8A 0 0 323 323 1 1
TET2 APOBEC3A 0 0 204 213 1 1
TET2 RING1 0 0 166 178 1 1
TET2 TFAM 0 0 60 210 1 2
TET2 TCF7 0 0 145 168 1 1
TET2 ID4 0 0 181 181 1 1
TET2 UHRF2 0 0 414 438 1 1
TET2 TNFRSF8 0 0 212 212 1 1
TET2 SLAMF1 0 0 301 306 1 1
TET2 NCOA3 0 0 57 178 1 1
TET2 RUNX3 0 0 248 248 1 1
TET2 NEIL2 0 0 123 157 1 1
TET2 PPAN 0 0 52 151 1 1
TET2 CD27 0 0 143 164 1 1
TET2 OOEP 0 0 113 152 1 1
TET2 SAP130 0 0 0 181 1 1
TET2 ARID5B 0 0 117 239 1 1
TET2 PRAM1 0 0 155 173 1 1
TET2 HOOK2 0 0 63 194 1 1
TET2 NCOA2 0 0 150 220 1 1
TET2 MANBA 0 0 0 206 1 1
TET2 HIC1 0 0 157 170 1 1
TET2 HSPA1A 270 0 0 270 1 1
TET2 ZBTB16 0 0 184 252 1 1
TET2 JAK3 0 0 425 424 1 1
TET2 HNRNPA1 0 0 69 181 1 1
TET2 BCL2L11 0 0 194 194 1 2
TET2 NTHL1 0 0 74 497 1 1
TET2 WDR5 0 0 294 400 1 1
TET2 DIDO1 0 0 0 183 1 1
TET2 BRD3 0 0 213 262 1 1
TET2 PHF13 0 0 47 211 1 1
TET2 OR1D2 0 0 74 179 1 1
TET2 TMEM255B 0 0 134 152 1 1
TET2 ARID5A 0 0 0 174 1 1
TET2 PLCG1 0 0 181 181 1 1
TET2 JUN 0 0 173 173 1 2
TET2 ZNF629 0 0 170 182 1 1
TET2 TYK2 0 0 218 218 1 1
TET2 DAPK1 0 0 218 218 1 2
TET2 HDAC4 0 0 206 230 1 2
TET2 HIST2H2AA3 0 0 340 349 1 1
TET2 FBXW7 0 0 391 414 1 2
TET2 IL3 0 0 293 301 1 1
TET2 CREB3L1 0 0 101 157 1 1
TET2 HSP90AA1 0 0 156 155 1 2
TET2 SETDB1 0 0 370 389 1 1
TET2 SETBP1 0 0 710 722 1 1
TET2 KDM1B 0 0 251 251 1 1
TET2 CRP 0 0 95 157 1 2
TET2 SUV39H1 0 0 358 431 1 1
TET2 SOX2 0 0 465 483 1 2
TET2 EPHA7 0 0 234 234 1 1
TET2 PRPF40B 0 0 334 334 1 1
TET2 SETD1A 0 0 455 459 1 1
TET2 CEBPA 0 0 739 739 1 1
TET2 HIST2H2AA 0 0 340 349 1 1
TET2 HOXA5 0 0 181 181 1 1
TET2 DNMT1 0 0 866 896 1 2
TET2 PRDM14 0 0 575 600 1 1
TET2 STUB1 0 0 517 517 1 2
TET2 INS 0 0 195 195 1 2
TET2 ACTB 270 0 325 495 1 2
TET2 WHSC1L1 0 0 158 179 1 1
TET2 ASH1L 0 0 97 423 1 1
TET2 PBX3 0 0 261 261 1 1
TET2 NIPBL 75 0 120 214 1 1
TET2 HIST1H4J 0 0 219 219 1 1
TET2 ANXA4 0 0 0 151 1 1
TET2 SQSTM1 0 0 49 152 1 2
TET2 ARID4B 0 0 0 389 1 1
TET2 MMP9 0 0 150 166 1 2
TET2 B2M 0 0 217 217 1 1
TET2 SUB1 270 0 0 270 1 1
TET2 KEAP1 270 0 131 338 1 2
TET2 PAX5 0 0 325 351 1 1
TET2 ROS1 0 0 171 190 1 1
TET2 MAPK3 0 0 172 171 1 2
TET2 SIRT3 0 0 218 218 1 2
TET2 CUL4A 0 0 108 154 1 1
TET2 PROM1 0 0 329 329 1 2
TET2 THY1 0 0 181 181 1 1
TET2 KMT2C 0 0 468 560 1 1
TET2 ABCG1 0 0 60 158 1 2
TET2 HSPA8 270 0 0 270 1 2
TET2 EPCAM 0 0 161 168 1 2
TET2 ASXL1 0 0 905 916 1 1
TET2 AR 0 0 219 219 1 2
TET2 PARP1 0 0 235 243 1 2
TET2 RHOA 0 0 370 370 1 2
TET2 HIST1H3D 0 0 184 219 1 1
TET2 MBD3 0 0 218 223 1 1
TET2 CDKN1A 0 0 166 171 1 2
TET2 HNRNPH1 270 0 0 290 1 1
TET2 BCLAF1 270 0 438 581 1 1
TET2 FGF4 0 0 213 224 1 1
TET2 CXCL12 0 0 140 271 1 2
TET2 RNF43 0 0 160 217 1 1
TET2 TPM1 270 0 0 270 1 1
TET2 MOSPD3 0 0 70 216 1 1
TET2 PIWIL1 0 0 202 325 1 1
TET2 KDM1A 0 0 464 485 1 2
TET2 ZBTB7B 0 0 204 216 1 1
TET2 EPC1 0 0 0 153 1 1
TET2 PTPRC 0 0 370 389 1 1
TET2 BCR 0 0 140 158 1 2
TET2 ZRSR2 0 0 738 738 1 1
TET2 PMCH 0 0 181 198 1 1
TET2 CEBPE 0 0 157 156 1 1
TET2 HBS1L 0 0 134 156 1 1
TET2 PBX1 0 0 181 181 1 1
TET2 ZNF711 0 0 46 265 1 1
TET2 TUBA1B 270 0 0 278 1 1
TET2 SUV420H2 0 0 134 168 1 1
TET2 GNB1 0 0 167 205 1 1
TET2 SOX9 0 0 161 161 1 1
TET2 DPPA3 0 0 537 537 1 1
TET2 MYH9 270 0 0 270 1 1
TET2 SIRT7 0 0 230 229 1 2
TET2 METTL4 0 0 47 194 1 1
TET2 THYN1 0 0 141 180 1 1
TET2 ENSG00000258724 0 0 134 282 1 1
TET2 ZEB1 0 0 213 230 1 2
TET2 BCORL1 0 0 594 594 1 1
TET2 ACLY 0 0 183 183 1 1
TET2 MAP3K19 0 0 143 167 1 1
TET2 STAT6 0 0 522 522 1 1
TET2 CXXC5 0 0 628 642 1 1
TET2 HNF4A 0 0 155 154 1 1
TET2 TCL1A 0 0 325 325 1 1
TET2 TRIM28 0 0 207 221 1 2
TET2 SLC25A5 0 0 0 190 1 1
TET2 CRTC1 0 0 94 150 1 2
TET2 MKL1 0 0 137 217 1 1
TET2 SMARCC1 0 0 166 250 1 1
TET2 SRC 0 0 209 209 1 2
TET2 XRCC2 0 0 88 152 1 1
TET2 EED 0 0 287 286 1 1
TET2 IRF8 0 0 218 247 1 1
TET2 SAMD9L 0 0 235 282 1 1
TET2 CBFB 0 0 177 261 1 1
TET2 KDM6A 0 0 603 614 1 1
TET2 METTL3 0 0 193 276 1 2
TET2 GATA5 0 0 108 163 1 1
TET2 KDM4B 0 0 235 246 1 1
TET2 FOXO3 0 0 931 935 1 2
TET2 BOLA2-SMG1P6 0 0 0 165 1 1
TET2 CTCF 0 0 507 547 1 1
TET2 CD2 0 0 223 223 1 1
TET2 CDKN1B 0 0 181 198 1 2
TET2 NUP214 0 0 323 332 1 1
TET2 RB1 0 0 140 172 1 2
TET2 CDA 0 0 241 245 1 1
TET2 POLRMT 0 0 0 199 1 1
TET2 STAT5B 0 0 574 578 1 1
TET2 TSC2 0 0 164 163 1 2
TET2 PPM1D 0 0 422 422 1 1
TET2 DDB1 270 0 113 392 1 1
TET2 DIS3 0 0 190 190 1 1
TET2 TM4SF19 0 0 120 210 1 1
TET2 GADD45G 0 0 74 158 1 1
TET2 IKZF2 0 0 339 349 1 1
TET2 ARID3B 0 0 46 196 1 1
TET2 PRMT5 0 0 722 722 1 1
TET2 RASSF1 0 0 260 260 1 1
TET2 ANPEP 0 0 252 252 1 1
TET2 KDR 0 0 150 282 1 2
TET2 RNF2 0 0 217 217 1 1
TET2 JAK1 0 0 403 416 1 2
TET2 SF3B1 0 0 294 359 1 1
TET2 YY1 0 0 180 192 1 1
TET2 NCR2 0 0 0 199 1 1
TET2 PRDM2 0 0 156 184 1 1
TET2 DNMT3L 0 0 821 821 1 1
TET2 LIN28B 0 0 134 161 1 1
TET2 METTL14 0 0 181 267 1 1
TET2 HIST1H4D 0 0 219 219 1 1
TET2 PEG3 0 0 194 206 1 2
TET2 FOXP3 0 0 478 554 1 2
TET2 KDM5A 0 0 293 343 1 1
TET2 PTPN6 0 0 181 181 1 1
TET2 ZKSCAN7 0 0 188 200 1 1
TET2 EIF2B2 270 0 0 273 1 1
TET2 SPEN 0 0 137 194 1 1
TET2 RUNX2 0 0 212 212 1 2
TET2 KMT2D 0 0 555 566 1 1
TET2 RAI1 270 0 0 286 1 1
TET2 DROSHA 0 0 169 253 1 1
TET2 SDHD 0 0 143 233 1 1
TET2 ARID3C 0 0 0 174 1 1
TET2 KLF4 0 0 421 452 1 2
TET2 SATB1 0 0 181 195 1 1
TET2 FGFR1 0 0 322 321 1 1
TET2 COL4A2 0 0 53 172 1 1
TET2 BRDT 0 0 170 176 1 1
TET2 CD4 0 0 377 377 1 2
TET2 MXD1 0 0 46 403 1 1
TET2 ARL15 0 0 202 219 1 1
TET2 HOXA10 0 0 194 194 1 1
TET2 FOXA1 0 0 216 232 1 1
TET2 CSF2 0 0 249 248 1 1
TET2 SP140 0 0 270 270 1 1
TET2 CD48 0 0 182 203 1 1
TET2 ZNF774 0 0 251 262 1 1
TET2 WEE2 0 0 0 188 1 1
TET2 CPT1A 0 0 75 217 1 1
TET2 AKT1 0 0 358 358 1 2
TET2 SPIB 0 0 95 187 1 1
TET2 HIST1H4C 0 0 219 219 1 1
TET2 PPARG 0 0 218 218 1 2
TET2 BCAT1 0 0 205 236 1 1
TET2 FUBP1 0 0 125 203 1 1
TET2 CD34 0 0 557 557 1 2
TET2 HMGA2 0 0 259 258 1 1
TET2 ASXL2 0 0 469 483 1 1
TET2 ERBB2 0 0 263 269 1 2
TET2 NKX2-8 0 0 142 175 1 1
TET2 HIST1H3G 0 0 124 162 1 1
TET2 CR2 0 0 81 156 1 1
TET2 SRGAP3 0 0 54 225 1 1
TET2 IGF2R 0 0 159 211 1 1
TET2 TPM3 270 0 0 270 1 1
TET2 CTCFL 0 0 315 334 1 1
TET2 ZNF521 0 0 118 265 1 1
TET2 NR5A2 0 0 139 157 1 1
TET2 MAP3K1 0 0 181 252 1 1
TET2 PMS2 0 0 181 181 1 1
TET2 GP2 0 0 60 231 1 1
TET2 RBBP5 0 0 134 157 1 1
TET2 AXL 0 0 164 163 1 2
TET2 FBXO15 0 0 108 170 1 1
TET2 HSP90AB1 270 0 0 286 1 2
TET2 BCL6 0 0 341 351 1 1
TET2 DDA1 0 0 70 175 1 1
TET2 TCEB2 270 0 0 270 1 1
TET2 ZSCAN4 0 0 246 284 1 1
TET2 SIRT4 0 0 233 232 1 1
TET2 CSMD3 0 0 125 320 1 1
TET2 SSRP1 0 0 75 235 1 1
TET2 EZH1 0 0 261 277 1 1
TET2 SOCS1 0 0 235 235 1 1
TET2 SYNE1 0 0 143 185 1 1
TET2 BTK 0 0 232 231 1 1
TET2 NUP54 0 0 54 155 1 1
TET2 KNSTRN 0 0 160 174 1 1
TET2 HIST1H3H 0 0 124 162 1 1
TET2 MAPK1 0 0 165 165 1 2
TET2 SUV39H2 0 0 164 259 1 1
TET2 APOB 0 0 112 167 1 2
TET2 CSF1R 0 0 262 262 1 1
TET2 PRPF8 0 0 230 229 1 1
TET2 MUS81 0 0 112 354 1 1
TET2 ATF3 0 0 108 203 1 2
TET2 CCDC107 0 0 112 307 1 1
TET2 PKM 0 0 182 181 1 1
TET2 ESRRB 0 0 459 473 1 1
TET2 GADD45A 0 0 322 390 1 1
TET2 GPS2 0 0 0 171 1 1
TET2 SUPT5H 0 0 0 175 1 1
TET2 KMT2A 0 0 529 829 1 1
TET2 SRSF2 0 0 811 824 1 1
TET2 FGF2 0 0 174 192 1 2
TET2 REST 0 0 159 172 1 2
TET2 GSTP1 0 0 134 168 1 1
TET2 PIK3C2G 0 0 124 227 1 1
TET2 PTCH1 0 0 232 334 1 1
TET2 NR0B1 0 0 143 173 1 1
TET2 U2AF2 0 0 267 267 1 1
TET2 TFRC 0 0 181 181 1 1
TET2 CCND2 0 0 202 202 1 1
TET2 HIST1H4H 0 0 219 219 1 1
TET2 YTHDF3 0 0 123 160 1 1
TET2 RBBP7 0 0 108 252 1 1
TET2 DDX3X 270 0 182 406 1 1
TET2 IKZF4 0 0 161 174 1 1
TET2 TFAP2C 0 0 128 193 1 1
TET2 ZNF207 270 0 0 270 1 1
TET2 ATP11B 0 0 180 197 1 1
TET2 NRIP1 0 0 54 257 1 1
TET2 IDH3A 0 0 124 184 1 1
TET2 KDM3A 0 0 294 314 1 1
TET2 VDR 0 0 785 785 1 2
TET2 CHIA 0 0 170 169 1 1
TET2 TDG 0 0 814 852 1 1
TET2 CGI-74 0 0 379 395 1 1
TET2 ITK 0 0 207 228 1 1
TET2 GFER 0 0 107 168 1 1
TET2 CD44 0 0 195 195 1 2
TET2 SIN3A 0 0 697 816 1 1
TET2 ANKRD26 0 0 195 195 1 1
TET2 BDNF 0 0 210 211 1 2
TET2 PRRC2C 0 0 0 265 1 1
TET2 TNF 0 0 218 224 1 2
TET2 CDK12 0 0 139 173 1 1
TET2 HNRNPD 0 0 47 170 1 1
TET2 RUNX1 0 0 459 459 1 2
TET2 TAL1 0 0 170 169 1 1
TET2 GFI1 0 0 155 168 1 1
TET2 ARID4A 0 0 66 365 1 1
TET2 DEK 0 0 473 473 1 1
TET2 MCM10 0 0 108 197 1 1
TET2 POU5F1 0 0 517 600 1 2
TET2 DMAP1 0 0 95 157 1 1
TET2 CCNE1 0 0 156 155 1 1
TET2 FH 0 0 359 359 1 1
TET2 KDM3B 0 0 167 187 1 1
TET2 L2HGDH 0 0 371 394 1 1
TET2 MECOM 0 0 334 344 1 1
TET2 HIST1H3F 0 0 124 162 1 1
TET2 ANXA7 0 0 0 189 1 1
TET2 MYB 0 0 206 262 1 1
TET2 HIST2H4B 0 0 219 219 1 1
TET2 FOXA2 0 0 124 176 1 1
TET2 CD38 0 0 310 309 1 2
TET2 AHCY 0 0 170 181 1 1
TET2 SAP30L 0 0 0 213 1 1
TET2 HPRT1 0 0 170 190 1 1
TET2 ETV2 0 0 108 270 1 1
TET2 CTLA4 0 0 294 294 1 2
TET2 SLC23A1 0 0 242 243 1 1
TET2 VPRBP 270 0 381 541 1 1
TET2 ELL 0 0 170 169 1 1
TET2 LIN28A 0 0 272 272 1 1
TET2 HDAC7 0 0 181 206 1 1
TET2 HNRNPA3 0 0 0 156 1 1
TET2 FLT3LG 0 0 181 181 1 1
TET2 NOS3 0 0 85 160 1 2
TET2 ZNF569 0 0 166 179 1 1
TET2 SAP30 0 0 0 245 1 1
TET2 PROCA1 0 0 75 217 1 1
TET2 MEIS1 0 0 390 394 1 1
TET2 MTF2 0 0 103 187 1 1
TET2 CCND1 0 0 302 302 1 2
TET2 CD274 0 0 278 278 1 2
TET2 BAALC 0 0 427 426 1 1
TET2 CD19 0 0 358 358 1 1
TET2 FGF5 0 0 150 173 1 1
TET2 PAXIP1 0 0 96 194 1 1
TET2 MED13L 0 0 54 167 1 1
TET2 MYO18A 0 0 128 188 1 1
TET2 ANXA2 270 0 0 315 1 1
TET2 ABCB5 0 0 51 151 1 1
TET2 PSPC1 0 0 490 490 1 1
TET2 HSPA9 270 0 72 293 1 1
TET2 CBL 0 0 336 336 1 1
TET2 C10orf2 0 0 60 158 1 1
TET2 EPOR 0 0 240 239 1 1
TET2 NTRK1 0 0 193 210 1 1
TET2 KLF1 0 0 410 419 1 1
TET2 HIST1H4B 0 0 219 219 1 1
TET2 DOT1L 0 0 464 463 1 1
TET2 NCOR1 0 0 397 410 1 1
TET2 PRKDC 0 0 108 154 1 2
TET2 LEPREL2 0 0 47 155 1 1
TET2 ETV6 0 0 633 641 1 1
TET2 HIST2H2BE 0 0 358 359 1 1
TET2 YWHAQ 486 0 0 485 1 1
TET2 OLIG2 0 0 157 156 1 1
TET2 KAT2B 0 0 219 254 1 1
TET2 FCGR1A 0 0 144 163 1 1
TET2 SNAI1 0 0 181 181 1 1
TET2 IL10 0 0 170 169 1 2
TET2 TACC2 0 0 120 208 1 1
TET2 PFN2 0 0 0 254 1 1
TET2 KDM4C 0 0 486 511 1 1
TET2 CHD4 0 0 212 219 1 1
TET2 RBPJ 0 0 108 163 1 1
TET2 COL1A1 0 0 109 185 1 2
TET2 KDM4D 0 0 244 243 1 1
TET2 NPM1 0 0 760 760 1 1
TET2 FLT3 0 0 759 763 1 2
TET2 CCAR1 0 0 0 156 1 1
TET2 SMARCC2 270 0 86 374 1 1
TET2 EGLN2 0 0 171 185 1 1
TET2 TF 270 0 0 270 1 2
TET2 ACTG1 0 0 157 158 1 1
TET2 IKZF1 0 0 519 526 1 1
TET2 ZNF750 0 0 170 169 1 1
TET2 RET 0 0 194 194 1 1
TET2 OGT 819 0 975 995 1 2
TET2 BAZ2B 0 0 81 255 1 1
TET2 MDM4 0 0 307 324 1 1
TET2 CCDC84 0 0 96 180 1 1
TET2 FCGR3B 0 0 155 154 1 1
TET2 IDH2 0 0 858 870 1 1
TET2 AXIN1 0 0 143 375 1 1
TET2 LEPREL1 0 0 53 160 1 1
TET2 SLC39A12 0 0 83 285 1 1
TET2 IGF2 0 0 243 242 1 1
TET2 JMJD1C 0 0 155 240 1 1
TET2 FRYL 0 0 0 217 1 1
TET2 UNG 0 0 233 243 1 1
TET2 ITGA2B 0 0 170 171 1 1
TET2 BRMS1 0 0 0 201 1 1
TET2 HIST1H1C 0 0 91 192 1 1
TET2 ATM 0 0 417 442 1 2
TET2 CSF3R 0 0 564 579 1 1
TET2 KAT5 0 0 202 219 1 1
TET2 MGEA5 0 0 138 176 1 1
TET2 ABCB7 0 0 194 194 1 1
TET2 HIST1H4K 0 0 219 219 1 1
TET2 SLC36A4 0 0 0 224 1 1
TET2 CD79A 0 0 183 183 1 1
TET2 HIST1H4A 0 0 219 219 1 1
TET2 CDX2 0 0 218 231 1 1
TET2 HIST1H3B 0 0 124 162 1 1
TET2 WT1 270 0 972 981 1 1
TET2 RARB 0 0 167 167 1 1
TET2 LDHA 270 0 193 385 1 2
TET2 ZBTB33 0 0 272 283 1 1
TET2 HIST1H3C 0 0 184 219 1 1
TET2 BMP4 0 0 150 188 1 1
TET2 TCF4 0 0 134 173 1 1
TET2 SYK 0 0 202 219 1 2
TET2 NUP98 0 0 380 393 1 1
TET2 PHF6 0 0 661 668 1 1
TET2 COMMD3-BMI1 0 0 292 293 1 1
TET2 KIT 0 0 653 653 1 2
TET2 SH3GL1 0 0 297 297 1 1
TET2 FGB 270 0 0 270 1 1
TET2 PCMT1 270 0 0 275 1 1
TET2 MYOD1 0 0 155 154 1 1
TET2 MLLT6 0 0 151 169 1 1
TET2 DNM1L 0 0 454 454 1 2
TET2 D2HGDH 0 0 314 384 1 1
TET2 HIST1H3A 0 0 124 162 1 1
TET2 KDM5C 0 0 242 270 1 1
TET2 IRF4 0 0 261 274 1 1
TET2 VEGFA 0 0 164 163 1 2
TET2 SNIP1 270 0 45 296 1 1
TET2 ARID2 0 0 341 445 1 1
TET2 SCAF1 0 0 162 234 1 1
TET2 TREML4 0 0 0 161 1 1
TET2 NCOA6 0 0 0 235 1 1
TET2 PTEN 0 0 424 438 1 2
TET2 SALL1 0 0 123 183 1 1
TET2 XBP1 0 0 75 171 1 2
TET2 SMC1B 0 0 73 457 1 1
TET2 UGGT2 0 0 171 171 1 1
TET2 ZNF281 0 0 0 245 1 1
TET2 OTX2 0 0 143 186 1 1
TET2 HIPK2 0 0 324 339 1 2
TET2 GATA6 0 0 233 232 1 1
TET2 TTC25 0 0 82 185 1 1
TET2 ELN 0 0 294 294 1 1
TET2 MPL 0 0 465 465 1 1
TET2 SAMD9 0 0 157 208 1 1
TET2 MLLT1 0 0 284 284 1 1
TET2 KCMF1 0 0 113 179 1 1
TET2 TUBB 270 0 0 270 1 1
TET2 GNA11 0 0 170 188 1 1
TET2 GATA2 0 0 606 606 1 1
TET2 PDCD1 0 0 210 210 1 2
TET2 ITGAM 0 0 234 234 1 1
TET2 DIO3 0 0 184 272 1 1
TET2 MSH2 0 0 261 261 1 1
TET2 ESR1 0 0 261 261 1 2
TET2 RBBP4 0 0 210 307 1 1
TET2 CHKB 0 0 95 185 1 1
TET2 NSD1 0 0 325 372 1 1
TET2 EHMT1 0 0 210 216 1 1
TET2 BCOR 0 0 651 656 1 1
TET2 CGGBP1 0 0 112 265 1 1
TET2 SPI1 0 0 946 947 1 1
TET2 TP53BP1 0 0 141 164 1 1
TET2 EOMES 0 0 213 319 1 1
TET2 MCL1 0 0 252 252 1 2
TET2 MYOCD 0 0 181 192 1 1
TET2 SMARCA4 270 0 369 519 1 1
TET2 MBNL1 0 0 113 202 1 1
TET2 SIRT1 0 0 321 335 1 2
TET2 DLK1 0 0 235 276 1 1
TET2 RARA 0 0 501 501 1 2
TET2 RAD51B 0 0 171 171 1 1
TET2 FN1 0 0 112 230 1 2
TET2 TBP 0 0 171 171 1 1
TET2 KDM5B 0 0 322 378 1 1
TET2 MN1 0 0 322 321 1 1
TET2 RCOR1 0 0 171 177 1 1
TET2 CXCR5 0 0 167 250 1 1
TET2 RPS18 270 0 0 270 1 1
TET2 THPO 0 0 486 485 1 1
TET2 ZBTB4 0 0 194 218 1 1
TET2 DPPA2 0 0 137 207 1 1
TET2 NCAM1 0 0 235 235 1 1
TET2 SETD2 0 0 470 493 1 1
TET2 TBX21 0 0 271 280 1 1
TET2 TENM3 0 0 77 220 1 1
TET2 PIGA 0 0 369 369 1 1
TET2 CHD3 0 0 173 180 1 1
TET2 STRA8 0 0 118 151 1 1
TET2 ARID1A 0 0 394 407 1 1
TET2 PEG10 0 0 210 221 1 1
TET2 ALKBH5 0 0 259 275 1 1
TET2 TERT 0 0 384 384 1 2
TET2 ANXA6 0 0 0 188 1 1
TET2 VAV1 0 0 288 288 1 1
TET2 GLI1 0 0 134 188 1 2
TET2 TRDMT1 0 0 391 456 1 1
TET2 FOS 0 0 180 186 1 2
TET2 KDM6B 0 0 403 403 1 1
TET2 GNMT 0 0 156 208 1 1
TET2 YWHAZ 270 0 0 270 1 1
TET2 BSX 0 0 0 183 1 1
TET2 SOCS3 0 0 150 217 1 1
TET2 U2AFBP 0 0 769 770 1 1
TET2 MATK 0 0 413 412 1 1
TET2 STAT5A 270 0 377 530 1 1
TET2 LMO1 0 0 150 208 1 1
TET2 RXRA 0 0 46 218 1 1
TET2 LMO2 0 0 240 239 1 1
TET2 ZFP42 0 0 261 286 1 1
TET2 TCEB1 270 0 0 270 1 1
TET2 PTPN11 0 0 601 601 1 1
TET2 ZGPAT 0 0 107 209 1 1
TET2 NRAS 0 0 708 708 1 1
TET2 PHF23 0 0 123 165 1 1
TET2 AVPR1A 0 0 54 345 1 1
TET2 HIST1H3J 0 0 124 162 1 1
TET2 KDM2B 0 0 325 343 1 1
TET2 LANCL1 270 0 0 270 1 1
TET2 HIST1H3E 0 0 184 219 1 1
TET2 BBX 0 0 0 190 1 1
TET2 EPAS1 0 0 67 200 1 2
TET2 HIST1H2BC 270 0 66 290 1 1
TET2 KRAS 0 0 522 532 1 2
TET2 RPS14 0 0 294 294 1 1
TET2 FOXO1 0 0 208 224 1 2
TET2 ZDHHC5 270 0 0 270 1 1
TET2 YTHDF1 0 0 140 191 1 1
TET2 ALKBH1 0 0 417 507 1 1
TET2 JMJD6 0 0 195 230 1 1
TET2 CDK9 0 0 144 163 1 1
TET2 MAPT 270 0 71 292 1 2
TET2 TFCP2L1 0 0 329 344 1 1
TET2 FBXL19 0 0 0 234 1 1
TET2 ABCB1 0 0 81 178 1 2
TET2 SDC1 0 0 100 238 1 1
TET2 IL2 0 0 234 234 1 1
TET2 ASH2L 0 0 134 156 1 1
TET2 PHIP 0 0 0 182 1 1
TET2 WEE1 0 0 95 233 1 1
TET2 SFRP2 0 0 156 155 1 1
TET2 DUSP1 0 0 95 190 1 1
TET2 CDKN2B 0 0 350 390 1 1
TET2 MLH1 0 0 325 325 1 1
TET2 RBM15 0 0 232 240 1 1
TET2 PARP2 0 0 150 169 1 1
TET2 MED1 270 0 0 270 1 1
TET2 MYH11 0 0 470 470 1 1
TET2 SOX7 0 0 134 328 1 1
TET2 CARD11 0 0 213 213 1 1
TET2 ENSG00000160201 0 0 769 770 1 1
TET2 EGLN1 0 0 325 336 1 1
TET2 BRCA2 0 0 323 323 1 1
TET2 HDAC9 0 0 243 266 1 1
TET2 REL 0 0 102 154 1 2
TET2 NLRP3 0 0 181 200 1 2
TET2 SLC23A2 0 0 289 289 1 1
TET2 RGN 0 0 0 418 1 1
TET2 DAXX 0 0 184 183 1 1
TET2 MLLT3 0 0 585 585 1 1
TET2 MBD4 0 0 464 545 1 1
TET2 CASP3 0 0 193 193 1 2
TET2 ARID3A 0 0 66 196 1 1
TET2 OR51Q1 0 0 142 232 1 1
TET2 KAT8 0 0 108 167 1 1
TET2 EEF1A1 270 0 61 287 1 1
TET2 KANSL1 0 0 112 152 1 1
TET2 AICDA 0 0 458 512 1 1
TET2 BCAR1 270 0 0 270 1 1
TET2 CXorf66 0 0 210 210 1 1
TET2 NOTCH2 0 0 266 282 1 1
TET2 ZNF142 0 0 75 154 1 1
TET2 SUDS3 0 0 46 264 1 1
TET2 RAD21 0 0 469 469 1 1
TET2 WTAP 0 0 145 166 1 1
TET2 SETD1B 0 0 261 277 1 1
TET2 CD5 0 0 234 234 1 1
TET2 CREBRF 0 0 123 215 1 1
TET2 CD28 0 0 213 213 1 1
TET2 HDAC11 0 0 180 205 1 1
TET2 TET1 0 600 907 724 1 1
TET2 DPEP1 0 0 0 181 1 1
TET2 HELLS 0 0 236 288 1 1
TET2 SMUG1 0 0 454 574 1 1
TET2 SMARCA1 0 0 210 210 1 1
TET2 NUDT9 0 0 47 150 1 1
TET2 CNOT3 0 0 97 153 1 1
TET2 CDKN2A 0 0 501 501 1 2
TET2 PBRM1 0 0 257 321 1 1
TET2 GSK3B 0 0 95 174 1 2
TET2 FAT4 0 0 150 180 1 1
TET2 SALL4 0 0 453 453 1 1
TET2 SAMHD1 0 0 138 169 1 1
TET2 HAT1 0 0 146 199 1 1
TET2 HIST1H3I 0 0 124 162 1 1
TET2 KLF2 0 0 253 264 1 1
TET2 HIST2H4A 0 0 219 219 1 1
TET2 NPAS4 0 0 207 228 1 1
TET2 CHD8 0 0 170 191 1 1
TET2 BANF1 0 0 204 204 1 1
TET2 SOX1 0 0 142 166 1 1
TET2 LAMB4 0 0 245 244 1 1
TET2 CEBPB 0 0 167 167 1 2
TET2 YWHAH 270 0 0 270 1 1
TET2 PHC3 0 0 57 225 1 1
TET2 HDAC1 0 0 675 733 1 2
TET2 MORF4L1 0 0 95 233 1 1
TET2 PRDM1 0 0 299 304 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0003677 Molecular Function DNA binding enables IEA
GO:0008198 Molecular Function ferrous iron binding enables IDA
GO:0070579 Molecular Function methylcytosine dioxygenase activity enables IBA
GO:0070579 Molecular Function methylcytosine dioxygenase activity enables IDA
GO:0070579 Molecular Function methylcytosine dioxygenase activity enables IMP
GO:0070579 Molecular Function methylcytosine dioxygenase activity enables ISS
GO:0005515 Molecular Function protein binding enables IPI
GO:0008270 Molecular Function zinc ion binding enables IDA
GO:0006211 Biological Process 5-methylcytosine catabolic process involved_in IDA
GO:0080111 Biological Process DNA demethylation involved_in IBA
GO:0080111 Biological Process DNA demethylation involved_in IDA
GO:0007049 Biological Process cell cycle involved_in IEA
GO:0006325 Biological Process chromatin organization involved_in IEA
GO:0002521 Biological Process leukocyte differentiation involved_in IMP
GO:0030099 Biological Process myeloid cell differentiation involved_in IBA
GO:0030099 Biological Process myeloid cell differentiation involved_in IMP
GO:0045944 Biological Process positive regulation of transcription by RNA polymerase II involved_in IBA
GO:0045944 Biological Process positive regulation of transcription by RNA polymerase II involved_in IMP
GO:0006493 Biological Process protein O-linked glycosylation involved_in IDA
GO:0006493 Biological Process protein O-linked glycosylation involved_in IMP
GO:0014070 Biological Process response to organic cyclic compound involved_in IEA
GO:0005694 Cellular Component chromosome located_in IEA
GO:0005654 Cellular Component nucleoplasm located_in TAS
GO:0005634 Cellular Component nucleus is_active_in IBA
Pathways
Name DB ID
Epigenetic regulation of gene expression Reactome R-HSA-212165
TET1,2,3 and TDG demethylate DNA Reactome R-HSA-5221030
Gene expression (Transcription) Reactome R-HSA-74160
Cytosine methylation (WP3585) WikiPathways WP3585_r123390
MECP2 and associated Rett syndrome (WP3584) WikiPathways WP3584_r123274
Transcripts
Accession Version MolecularType Name NCBI Comments
XR_007057933 1 miscRNA transcript variant X11 NC_000004 Reference
XM_024454103 2 mRNA transcript variant X2 NC_000004 Reference
NM_017628 4 mRNA transcript variant 2 NC_000004 Reference
XM_024454102 2 mRNA transcript variant X3 NC_000004 Reference
NM_001127208 3 mRNA transcript variant 1 NC_000004 Reference
XM_006714242 4 mRNA transcript variant X4 NC_000004 Reference
XM_005263082 4 mRNA transcript variant X1 NC_000004 Reference
XM_047415839 1 mRNA transcript variant X5 NC_000004 Reference
XM_047415840 1 mRNA transcript variant X6 NC_000004 Reference
XM_047415841 1 mRNA transcript variant X7 NC_000004 Reference
XM_047415842 1 mRNA transcript variant X9 NC_000004 Reference
XM_017008319 2 mRNA transcript variant X8 NC_000004 Reference
XM_047415843 1 mRNA transcript variant X10 NC_000004 Reference