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PNPLA2

patatin like phospholipase domain containing 2
General Information
Name patatin like phospholipase domain containing 2
Alias
  • patatin-like phospholipase domain-containing protein 2
  • IPLA2-zeta
  • TTS2.2
  • adipose triglyceride lipase
  • calcium-independent phospholipase A2
  • calcium-independent phospholipase A2-zeta
  • desnutrin
  • mutant patatin-like phospholipase domain containing 2
  • pigment epithelium-derived factor
  • pigment epithelium-derived factor receptor
  • transport-secretion protein 2.2
  • triglyceride hydrolase
Gene_family Patatin like phospholipase domain containing|Lipases
organism Homo sapiens
entrez_id 57104
location 11p15.5
transcript_count 1
exon_count 10
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez This gene encodes an enzyme which catalyzes the first step in the hydrolysis of triglycerides in adipose tissue. Mutations in this gene are associated with neutral lipid storage disease with myopathy. [provided by RefSeq, Jul 2010]
    Stringdb Patatin-like phospholipase domain-containing protein 2; Catalyzes the initial step in triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets. Also has acylglycerol transacylase activity. May act coordinately with LIPE/HLS within the lipolytic cascade. Regulates adiposome size and may be involved in the degradation of adiposomes. May play an important role in energy homeostasis. May play a role in the response of the organism to starvation, enhancing hydrolysis of triglycerides and providing free fatty acids to other tissues to be oxidized in situations of energy depletio [...]
    nextProt Catalyzes the initial step in triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets (PubMed:15550674, PubMed:15364929, PubMed:16150821, PubMed:17603008, PubMed:16239926, PubMed:34903883). Exhibits a strong preference for the hydrolysis of long-chain fatty acid esters at the sn-2 position of the glycerol backbone and acts coordinately with LIPE/HLS and DGAT2 within the lipolytic cascade (By similarity). Also possesses acylglycerol transacylase and phospholipase A2 activities (PubMed:15364929, PubMed:17032652, PubMed:17603008). Transfers fatty acid from triglyceride to retinol, hydrolyzes retinylesters, and generates 1,3-diacylglycerol from triglycerides (PubMed:17603008). Regulates adiposome size and may be involved in the degradation of adiposomes (PubMed:16239926). May play an important role in energy homeostasis (By similarity). May play a role in the response of the organism to starvation, enhancing hydrolysis of triglycerides and providing free fatty acids to other tissues to be oxidized in situations of energy depletion (By similarity).
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
PNPLA2 BioGRID TOP3B GeneID BioGRID Affinity Capture-RNA
PNPLA2 BioGRID D2HGDH GeneID BioGRID Affinity Capture-MS
PNPLA2 BioGRID ZHX1-C8orf76 GeneID BioGRID Affinity Capture-MS
PNPLA2 BioGRID PLEKHG7 GeneID BioGRID Affinity Capture-MS
PNPLA2 BioGRID ASB14 GeneID BioGRID Affinity Capture-MS
PNPLA2 BioGRID CIAO2A GeneID BioGRID Affinity Capture-MS
PNPLA2 BioGRID G0S2 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
PNPLA2 BioGRID SULT1C4 GeneID BioGRID Affinity Capture-MS
PNPLA2 BioGRID GIMAP2 GeneID BioGRID Affinity Capture-MS
PNPLA2 BioGRID SF3B3 GeneID BioGRID Affinity Capture-MS
PNPLA2 BioGRID ALDH1L1 GeneID BioGRID Affinity Capture-MS
PNPLA2 BioGRID PTGES3 GeneID BioGRID Affinity Capture-MS
PNPLA2 BioGRID TXNRD2 GeneID BioGRID Affinity Capture-MS
PNPLA2 BioGRID B4GALT2 GeneID BioGRID Affinity Capture-MS
PNPLA2 BioGRID PEX14 GeneID BioGRID Affinity Capture-MS
PNPLA2 BioGRID SCGB2A2 GeneID BioGRID Affinity Capture-MS
PNPLA2 BioGRID F12 GeneID BioGRID Affinity Capture-MS
PNPLA2 BioGRID CTAG1B GeneID BioGRID Affinity Capture-MS
PNPLA2 BioGRID ALOX5 GeneID BioGRID Affinity Capture-MS
PNPLA2 BioGRID CD274 GeneID BioGRID Affinity Capture-MS
PNPLA2 BioGRID ORF7b GeneID BioGRID Affinity Capture-MS
PNPLA2 BioGRID COP1 GeneID BioGRID Affinity Capture-Western
PNPLA2 BioGRID TRIM25 GeneID BioGRID Affinity Capture-RNA
PNPLA2 BioGRID TIMM29 GeneID BioGRID Affinity Capture-MS
PNPLA2 BioGRID ABHD5 GeneID BioGRID Affinity Capture-Western; FRET; PCA
PNPLA2 BioGRID FKBP5 GeneID BioGRID Affinity Capture-Luminescence; Affinity Capture-MS
PNPLA2 BioGRID Abhd5 GeneID BioGRID Reconstituted Complex
PNPLA2 BioGRID ARFGEF2 GeneID BioGRID Affinity Capture-Western; Two-hybrid
PNPLA2 BioGRID CYTH2 GeneID BioGRID Affinity Capture-Western; Two-hybrid
PNPLA2 BioGRID GBF1 GeneID BioGRID Affinity Capture-Western; Co-localization; Reconstituted Complex; Two-hybrid
PNPLA2 BioGRID FAF2 GeneID BioGRID Affinity Capture-Western; PCA
PNPLA2 BioGRID SERPINF1 GeneID BioGRID Reconstituted Complex; Two-hybrid
PNPLA2 BioGRID SMAD9 GeneID BioGRID Two-hybrid
PNPLA2 BioGRID UBE2R2 GeneID BioGRID Two-hybrid
PNPLA2 None PHYHIP GeneID HPRD
PNPLA2 None SMAD9 GeneID HPRD
PNPLA2 None MARK3 GeneID HPRD
PNPLA2 BioGRID PHYHIP GeneID BioGRID Two-hybrid
PNPLA2 BioGRID MARK3 GeneID BioGRID Two-hybrid
PNPLA2 Protein None None BIND ATGL interacts with NDB-HEHP.
StringDB
A B experiments database textmining combined score hadb nhadb
PNPLA2 ADIPOQ 0 0 668 703 1 2
PNPLA2 ARG1 0 0 181 181 1 2
PNPLA2 PRKAB1 0 0 166 180 1 2
PNPLA2 GRINA 0 0 0 223 1 1
PNPLA2 TRAPPC11 0 0 0 271 1 1
PNPLA2 CPT1B 0 0 601 634 1 1
PNPLA2 NR3C1 0 0 241 240 1 1
PNPLA2 OSBPL7 0 0 0 166 1 1
PNPLA2 TNS1 0 0 93 157 1 1
PNPLA2 ZNF679 0 0 161 161 1 1
PNPLA2 GNPAT 0 0 165 228 1 1
PNPLA2 CEBPD 0 0 261 304 1 1
PNPLA2 RPTOR 0 0 284 321 1 2
PNPLA2 KCTD6 0 0 66 165 1 1
PNPLA2 TBC1D5 0 0 0 161 1 2
PNPLA2 CFD 0 0 310 352 1 1
PNPLA2 MFSD2A 0 0 113 187 1 1
PNPLA2 AKR1B1 0 0 123 214 1 1
PNPLA2 RNF19A 0 0 47 167 1 1
PNPLA2 PRKAB2 0 0 135 150 1 1
PNPLA2 GPAT2 0 0 404 411 1 1
PNPLA2 ARFRP1 0 0 375 439 1 1
PNPLA2 FASN 0 0 684 744 1 2
PNPLA2 RPS6KA4 0 0 0 175 1 1
PNPLA2 POMC 0 0 287 288 1 1
PNPLA2 PTDSS1 0 0 97 159 1 1
PNPLA2 PEX12 0 0 0 189 1 1
PNPLA2 ABHD3 0 0 129 181 1 1
PNPLA2 PIP5K1C 0 0 0 150 1 1
PNPLA2 ENPP2 0 0 150 208 1 1
PNPLA2 AUP1 0 0 392 427 1 1
PNPLA2 XKR4 0 0 0 185 1 1
PNPLA2 KAT2A 0 0 67 171 1 1
PNPLA2 ADRB3 0 0 634 647 1 1
PNPLA2 PGK1 0 0 134 151 1 2
PNPLA2 AOAH 0 0 70 173 1 1
PNPLA2 LEPR 0 0 337 406 1 1
PNPLA2 SDHA 0 0 170 169 1 1
PNPLA2 ACAA1 0 0 232 267 1 1
PNPLA2 DNM2 0 0 125 228 1 1
PNPLA2 CPTP 0 0 0 152 1 1
PNPLA2 ABCA1 0 0 325 341 1 2
PNPLA2 DPP4 0 0 120 180 1 1
PNPLA2 XKR9 0 0 0 202 1 1
PNPLA2 FKBP5 131 0 66 172 1 1
PNPLA2 LGALS4 0 0 142 179 1 1
PNPLA2 MLXIPL 0 0 529 547 1 1
PNPLA2 HSD17B11 0 0 213 307 1 1
PNPLA2 SEC31B 0 0 73 235 1 1
PNPLA2 CERS2 0 0 107 216 1 1
PNPLA2 PLA2G10 0 0 416 426 1 1
PNPLA2 HMGCS2 0 0 325 350 1 1
PNPLA2 MTTP 0 0 505 555 1 1
PNPLA2 PLA2G1B 0 0 459 517 1 1
PNPLA2 OSBPL6 0 0 0 162 1 1
PNPLA2 KDM1A 0 0 171 190 1 2
PNPLA2 ABTB1 0 0 0 166 1 1
PNPLA2 CRTC2 0 0 219 258 1 1
PNPLA2 INSR 0 0 234 314 1 1
PNPLA2 HSPA8 0 0 186 205 1 2
PNPLA2 PLIN5 0 0 986 993 1 1
PNPLA2 GABARAPL1 0 0 155 155 1 2
PNPLA2 UNC93B1 0 0 0 153 1 1
PNPLA2 SIRT7 0 0 230 229 1 2
PNPLA2 ELOVL3 0 0 391 399 1 1
PNPLA2 MPC1 0 0 102 158 1 1
PNPLA2 LRRC56 0 0 218 547 1 1
PNPLA2 PLA2G2D 0 0 268 281 1 1
PNPLA2 COX4I1 0 0 323 323 1 1
PNPLA2 CEBPA 0 0 616 647 1 1
PNPLA2 CELA3B 0 0 55 158 1 1
PNPLA2 MBOAT1 0 0 134 162 1 1
PNPLA2 ACAA2 0 0 210 280 1 1
PNPLA2 LPPR2 0 0 0 175 1 1
PNPLA2 HADHA 0 0 324 402 1 1
PNPLA2 TFEB 0 0 297 325 1 2
PNPLA2 CAPN12 0 0 141 208 1 1
PNPLA2 DPP7 0 0 52 239 1 1
PNPLA2 SIRT3 0 0 281 298 1 2
PNPLA2 B2M 0 0 122 158 1 1
PNPLA2 GLP1R 0 0 161 161 1 1
PNPLA2 PAFAH2 0 0 113 162 1 1
PNPLA2 FOXG1 0 0 46 234 1 1
PNPLA2 ACTB 0 0 527 549 1 2
PNPLA2 INS 0 0 701 708 1 2
PNPLA2 CAV1 0 0 298 298 1 2
PNPLA2 ELOVL4 0 0 218 236 1 1
PNPLA2 HAO2 0 0 0 157 1 1
PNPLA2 OGDH 0 0 108 183 1 1
PNPLA2 FFAR2 0 0 210 210 1 1
PNPLA2 ULK2 0 0 57 153 1 2
PNPLA2 REXO1 0 0 0 161 1 1
PNPLA2 AKT1S1 0 0 155 248 1 1
PNPLA2 CASP1 0 0 180 218 1 2
PNPLA2 MGRN1 0 0 0 179 1 1
PNPLA2 TAZ 0 0 299 357 1 1
PNPLA2 R3HDM4 0 0 0 151 1 1
PNPLA2 DPP9 0 0 52 173 1 1
PNPLA2 NRF1 0 0 325 325 1 2
PNPLA2 ARFGEF2 270 0 0 270 1 1
PNPLA2 LRAT 0 0 193 203 1 1
PNPLA2 C19orf12 0 0 161 161 1 1
PNPLA2 TICAM1 0 0 0 151 1 2
PNPLA2 VCP 0 0 150 259 1 2
PNPLA2 YWHAE 0 0 62 158 1 1
PNPLA2 TFAM 0 0 391 404 1 2
PNPLA2 FZR1 0 0 0 150 1 1
PNPLA2 NAT8L 0 0 209 238 1 1
PNPLA2 MAT2A 0 0 0 158 1 1
PNPLA2 TCIRG1 0 0 0 171 1 1
PNPLA2 ATP5B 0 0 181 181 1 1
PNPLA2 RBP4 0 0 305 309 1 1
PNPLA2 WDFY1 0 0 61 213 1 1
PNPLA2 PEMT 0 0 261 277 1 1
PNPLA2 CALR 0 0 193 193 1 1
PNPLA2 SCAP 0 0 157 181 1 1
PNPLA2 GPD1 0 0 209 263 1 1
PNPLA2 PRDX6 0 0 345 361 1 1
PNPLA2 FGF21 0 0 563 572 1 2
PNPLA2 CS 0 0 324 336 1 1
PNPLA2 FBXO32 0 0 293 364 1 2
PNPLA2 PXYLP1 0 0 0 188 1 1
PNPLA2 ACOT4 0 0 202 228 1 1
PNPLA2 APOA4 0 0 263 268 1 1
PNPLA2 ZSCAN29 0 0 113 202 1 1
PNPLA2 CIDEC 0 0 870 877 1 1
PNPLA2 ELOVL2 0 0 92 178 1 1
PNPLA2 MBOAT7 0 0 260 306 1 1
PNPLA2 PRKACA 0 0 0 207 1 1
PNPLA2 TMEM26 0 0 334 375 1 1
PNPLA2 BCKDHA 0 0 108 156 1 1
PNPLA2 PFKL 0 0 81 165 1 1
PNPLA2 ARF1 0 0 390 430 1 1
PNPLA2 LRSAM1 0 0 53 288 1 2
PNPLA2 PHRF1 0 0 74 156 1 1
PNPLA2 GAPT 0 0 0 286 1 1
PNPLA2 APOA1 0 0 261 261 1 1
PNPLA2 AGPAT5 0 0 172 328 1 1
PNPLA2 VWA7 0 0 0 211 1 1
PNPLA2 EMR1 0 0 150 238 1 1
PNPLA2 TLR4 0 0 260 276 1 2
PNPLA2 RAB18 0 0 592 664 1 1
PNPLA2 PHYH 0 0 130 155 1 1
PNPLA2 PDDC1 0 0 139 288 1 1
PNPLA2 ATG14 0 0 168 167 1 2
PNPLA2 LIPM 0 0 170 324 1 1
PNPLA2 BCL2L1 0 0 90 156 1 2
PNPLA2 ME1 0 0 208 233 1 1
PNPLA2 PPAP2C 0 650 66 740 1 1
PNPLA2 ACSS2 0 0 345 382 1 1
PNPLA2 SLC25A20 0 0 413 450 1 1
PNPLA2 TFB1M 0 0 139 180 1 1
PNPLA2 ACSL3 0 600 414 770 1 1
PNPLA2 PLA2G4A 0 0 450 450 1 1
PNPLA2 ACSL5 0 600 321 739 1 1
PNPLA2 PRKAR2B 0 0 96 150 1 1
PNPLA2 MAP1LC3A 0 0 134 171 1 2
PNPLA2 LIPE 0 900 913 995 1 1
PNPLA2 RETSAT 0 0 107 254 1 1
PNPLA2 PEX11A 0 0 123 261 1 1
PNPLA2 ACVR1C 0 0 160 159 1 1
PNPLA2 GCK 0 0 325 355 1 1
PNPLA2 SIRT5 0 0 234 234 1 1
PNPLA2 PYGL 0 0 170 210 1 1
PNPLA2 HIF1A 0 0 255 276 1 2
PNPLA2 IL1B 0 0 367 368 1 2
PNPLA2 CROT 0 0 189 204 1 1
PNPLA2 XK 0 0 0 156 1 1
PNPLA2 LY6G6C 0 0 67 174 1 1
PNPLA2 PRKG1 0 0 113 155 1 1
PNPLA2 UCP2 0 0 510 530 1 2
PNPLA2 ABHD12 0 0 181 269 1 1
PNPLA2 IL6 0 0 459 459 1 2
PNPLA2 SAA1 0 0 123 156 1 1
PNPLA2 SORT1 0 0 59 154 1 1
PNPLA2 ACOT2 0 0 181 212 1 1
PNPLA2 POTEF 0 0 180 218 1 1
PNPLA2 LYPLA1 0 0 97 159 1 1
PNPLA2 PEX19 0 0 157 283 1 1
PNPLA2 MRPS6 0 0 0 206 1 1
PNPLA2 PIDD1 0 0 95 161 1 1
PNPLA2 PTGS1 0 0 155 180 1 1
PNPLA2 SPSB3 0 0 95 157 1 1
PNPLA2 PNLIP 0 800 391 902 1 1
PNPLA2 DDIT3 0 0 154 169 1 2
PNPLA2 CHPT1 0 0 293 303 1 1
PNPLA2 PRKACG 0 0 0 176 1 1
PNPLA2 LIPN 0 0 124 240 1 1
PNPLA2 SNAP23 0 0 202 202 1 1
PNPLA2 LMNA 0 0 123 155 1 2
PNPLA2 SLC2A2 0 0 294 302 1 1
PNPLA2 LIPH 0 0 181 197 1 1
PNPLA2 ACSL6 0 600 134 683 1 1
PNPLA2 HK2 0 0 270 303 1 2
PNPLA2 DECR1 0 0 96 245 1 1
PNPLA2 MOGAT1 0 650 341 801 1 1
PNPLA2 FFAR1 0 0 219 219 1 1
PNPLA2 CHSY3 0 0 0 267 1 1
PNPLA2 LACTB 0 0 90 230 1 1
PNPLA2 CCRN4L 0 0 134 182 1 1
PNPLA2 PRKCE 0 0 193 194 1 1
PNPLA2 ABHD17B 0 0 91 192 1 1
PNPLA2 FITM2 0 0 342 365 1 1
PNPLA2 CPT2 0 0 517 531 1 1
PNPLA2 PLIN4 0 0 620 665 1 1
PNPLA2 PPP1R12C 0 0 0 156 1 1
PNPLA2 STAT3 0 0 241 240 1 2
PNPLA2 C1QTNF7 0 0 74 410 1 1
PNPLA2 ERN1 0 0 218 235 1 2
PNPLA2 AQP7 0 0 392 400 1 1
PNPLA2 SERAC1 0 0 45 164 1 1
PNPLA2 TMA16 0 0 0 190 1 1
PNPLA2 TSC22D3 0 0 59 151 1 1
PNPLA2 GLI4 0 0 0 161 1 1
PNPLA2 XKR6 0 0 0 185 1 1
PNPLA2 CES3 0 0 457 466 1 1
PNPLA2 SBNO2 0 0 0 205 1 1
PNPLA2 ACACA 0 0 654 692 1 1
PNPLA2 SDHC 0 0 157 156 1 1
PNPLA2 IGF1R 0 0 112 205 1 2
PNPLA2 KLB 0 0 276 276 1 1
PNPLA2 MYC 0 0 169 169 1 2
PNPLA2 CYP51A1 0 0 155 154 1 1
PNPLA2 TBC1D24 0 0 97 234 1 1
PNPLA2 FABP7 0 0 138 161 1 1
PNPLA2 ACOT11 0 0 214 285 1 1
PNPLA2 NPY 0 0 263 263 1 1
PNPLA2 FURIN 0 0 0 189 1 1
PNPLA2 PFKM 0 0 231 256 1 1
PNPLA2 CEL 0 800 212 851 1 1
PNPLA2 CALCOCO1 0 0 66 167 1 1
PNPLA2 NFE2L2 0 0 174 173 1 2
PNPLA2 ZNF423 0 0 261 261 1 1
PNPLA2 CIDEA 0 0 651 666 1 1
PNPLA2 ACAD9 0 0 137 172 1 1
PNPLA2 AKT2 0 0 262 296 1 2
PNPLA2 ACSL1 0 600 560 820 1 1
PNPLA2 NGDN 0 0 55 171 1 1
PNPLA2 HDAC3 0 0 81 157 1 2
PNPLA2 CIDEB 0 0 371 417 1 1
PNPLA2 CYTH2 270 0 0 270 1 1
PNPLA2 ULK1 0 0 202 321 1 2
PNPLA2 TBP 0 0 134 160 1 1
PNPLA2 CRACR2B 0 0 113 296 1 1
PNPLA2 PYURF 0 0 135 289 1 1
PNPLA2 XKR7 0 0 53 263 1 1
PNPLA2 AGPAT4 0 0 267 387 1 1
PNPLA2 ADRB1 0 0 241 318 1 1
PNPLA2 XKR3 0 0 0 156 1 1
PNPLA2 HADHB 0 0 260 305 1 1
PNPLA2 AGFG1 0 0 103 159 1 1
PNPLA2 SPHK2 0 0 134 152 1 1
PNPLA2 MAP1LC3B 0 0 261 270 1 2
PNPLA2 HHAT 0 0 0 151 1 1
PNPLA2 LSS 0 0 171 211 1 1
PNPLA2 SPHK1 0 0 150 171 1 2
PNPLA2 PPT1 0 0 57 150 1 1
PNPLA2 C2orf43 0 0 261 375 1 1
PNPLA2 PDIA5 0 0 415 427 1 1
PNPLA2 PANK1 0 0 155 154 1 1
PNPLA2 SLC22A5 0 0 181 190 1 1
PNPLA2 COX7A1 0 0 155 173 1 1
PNPLA2 APOA5 0 0 233 249 1 1
PNPLA2 EPHX1 0 0 58 246 1 1
PNPLA2 PTDSS2 0 0 217 259 1 1
PNPLA2 ACADS 0 0 248 371 1 1
PNPLA2 ABCD1 0 0 0 159 1 1
PNPLA2 CES4A 0 0 122 218 1 1
PNPLA2 TLE3 0 0 138 191 1 1
PNPLA2 PLIN2 0 0 953 963 1 2
PNPLA2 FKTN 0 0 88 249 1 1
PNPLA2 BBS5 0 0 0 463 1 1
PNPLA2 OSBP 0 0 122 177 1 1
PNPLA2 PDK4 0 0 558 571 1 1
PNPLA2 NCL 0 0 113 221 1 2
PNPLA2 ESR1 0 0 195 195 1 2
PNPLA2 LDHA 0 0 167 185 1 2
PNPLA2 STX3 0 0 155 173 1 1
PNPLA2 DOCK4 0 0 49 188 1 1
PNPLA2 IAH1 0 0 184 251 1 1
PNPLA2 SLC27A2 0 0 391 416 1 1
PNPLA2 ACSL4 0 600 341 741 1 1
PNPLA2 ASCL3 0 0 120 272 1 1
PNPLA2 POU2F3 0 0 182 181 1 1
PNPLA2 ABHD1 0 0 146 294 1 1
PNPLA2 CERK 0 0 124 178 1 1
PNPLA2 TRIM47 0 0 0 157 1 1
PNPLA2 HSDL1 0 0 150 275 1 1
PNPLA2 PAPLN 0 0 0 201 1 1
PNPLA2 DGKI 0 650 0 656 1 1
PNPLA2 DYRK1B 0 0 0 164 1 1
PNPLA2 HCAR1 0 0 170 189 1 1
PNPLA2 CPLX2 0 0 0 248 1 1
PNPLA2 NR1H4 0 0 321 329 1 1
PNPLA2 IL10 0 0 229 228 1 2
PNPLA2 CEPT1 0 0 235 235 1 1
PNPLA2 COL4A3BP 0 0 103 228 1 1
PNPLA2 GOT2 0 0 466 487 1 1
PNPLA2 PFDN6 0 0 0 232 1 1
PNPLA2 PNPLA3 0 800 943 819 1 1
PNPLA2 TTC39B 0 0 81 295 1 1
PNPLA2 AGPAT2 0 0 464 551 1 1
PNPLA2 TTR 0 0 96 214 1 1
PNPLA2 MRC1 0 0 178 196 1 1
PNPLA2 GSK3B 0 0 108 182 1 2
PNPLA2 BDH1 0 0 225 226 1 1
PNPLA2 ETFB 0 0 134 165 1 1
PNPLA2 PEX14 130 0 0 183 1 2
PNPLA2 PKP3 0 0 66 327 1 1
PNPLA2 CEBPB 0 0 464 517 1 2
PNPLA2 ACOT1 0 0 286 313 1 1
PNPLA2 EIF4B 0 0 0 230 1 1
PNPLA2 HADH 0 0 386 415 1 1
PNPLA2 ADAT3 0 0 0 150 1 1
PNPLA2 PTGS2 0 0 218 218 1 2
PNPLA2 CASP3 0 0 324 338 1 2
PNPLA2 CTSZ 0 0 0 174 1 1
PNPLA2 NLRP3 0 0 202 202 1 2
PNPLA2 AGPAT9 0 0 466 497 1 1
PNPLA2 ACSM3 0 0 0 188 1 1
PNPLA2 PLA2G7 0 0 294 336 1 1
PNPLA2 PLA2G6 0 0 803 814 1 1
PNPLA2 INTS1 0 0 0 175 1 1
PNPLA2 COL6A2 0 0 57 173 1 1
PNPLA2 PPME1 0 0 67 257 1 1
PNPLA2 ABHD4 0 0 335 673 1 1
PNPLA2 PNPLA4 0 0 910 151 1 1
PNPLA2 ACADL 0 0 468 492 1 1
PNPLA2 MOGAT2 0 650 231 768 1 1
PNPLA2 BECN1 0 0 241 240 1 2
PNPLA2 COX4I2 0 0 171 171 1 1
PNPLA2 OLR1 0 0 81 158 1 2
PNPLA2 GYS1 0 0 139 170 1 1
PNPLA2 LPCAT2 0 0 293 334 1 1
PNPLA2 LPIN1 0 650 520 846 1 2
PNPLA2 ACOX3 0 0 212 312 1 1
PNPLA2 GABBR1 0 0 46 252 1 1
PNPLA2 ACADVL 0 0 468 511 1 1
PNPLA2 SAR1B 0 0 108 169 1 1
PNPLA2 CILP2 0 0 0 190 1 1
PNPLA2 STRA6 0 0 112 157 1 1
PNPLA2 SCD5 0 0 233 301 1 1
PNPLA2 RXRA 0 0 124 206 1 1
PNPLA2 STAT5A 0 0 147 178 1 1
PNPLA2 GNMT 0 0 74 302 1 1
PNPLA2 FBRS 0 0 0 151 1 1
PNPLA2 SOCS3 0 0 181 245 1 1
PNPLA2 FITM1 0 0 154 201 1 1
PNPLA2 ADAM15 0 0 0 157 1 1
PNPLA2 PNPLA1 0 0 561 173 1 1
PNPLA2 PAFAH1B2 0 0 122 265 1 1
PNPLA2 MAFK 0 0 0 319 1 1
PNPLA2 VLDLR 0 0 255 274 1 1
PNPLA2 NDOR1 0 0 0 159 1 1
PNPLA2 WDR81 0 0 0 171 1 1
PNPLA2 GYS2 0 0 324 338 1 1
PNPLA2 SIRT4 0 0 230 229 1 1
PNPLA2 GSK3A 0 0 61 166 1 1
PNPLA2 SIAE 0 0 67 166 1 1
PNPLA2 SLC7A2 0 0 0 159 1 1
PNPLA2 KLF4 0 0 97 177 1 2
PNPLA2 COL6A1 0 0 123 228 1 1
PNPLA2 IKBKB 0 0 134 152 1 2
PNPLA2 ATF6 0 0 184 226 1 2
PNPLA2 ABCG8 0 0 142 160 1 1
PNPLA2 DLG1 0 0 453 453 1 1
PNPLA2 KDSR 0 0 0 153 1 1
PNPLA2 FABP2 0 0 208 223 1 1
PNPLA2 MTMR10 0 0 0 159 1 1
PNPLA2 CES5A 0 0 73 166 1 1
PNPLA2 PPARG 0 0 739 748 1 2
PNPLA2 AKT1 0 0 502 541 1 2
PNPLA2 ENSG00000260272 0 0 0 187 1 1
PNPLA2 PCYT1A 0 0 132 235 1 1
PNPLA2 ACOX2 0 0 170 188 1 1
PNPLA2 PRDM16 0 0 518 531 1 1
PNPLA2 LYPLAL1 0 0 146 276 1 1
PNPLA2 TSC2 0 0 173 195 1 2
PNPLA2 MC4R 0 0 180 191 1 1
PNPLA2 RBP1 0 0 153 238 1 1
PNPLA2 ABCD3 0 0 150 186 1 1
PNPLA2 DPP8 0 0 60 176 1 1
PNPLA2 APOC2 0 0 241 263 1 1
PNPLA2 HMOX1 0 0 150 185 1 2
PNPLA2 DGKB 0 650 63 669 1 1
PNPLA2 COASY 0 0 350 364 1 1
PNPLA2 LGALS3 0 0 155 190 1 2
PNPLA2 ACLY 0 0 503 523 1 1
PNPLA2 APOD 0 0 134 263 1 1
PNPLA2 STK25 0 0 54 154 1 1
PNPLA2 EIF2AK3 0 0 232 269 1 2
PNPLA2 PCSK9 0 0 132 198 1 1
PNPLA2 ETFDH 0 0 245 244 1 1
PNPLA2 TM6SF2 0 0 263 284 1 1
PNPLA2 KIF5B 0 0 52 182 1 1
PNPLA2 YWHAB 0 0 84 178 1 1
PNPLA2 DGAT2 0 650 733 919 1 1
PNPLA2 CHDH 0 0 90 152 1 1
PNPLA2 SCD 0 0 652 683 1 1
PNPLA2 SRC 0 0 143 174 1 2
PNPLA2 ADH5 0 0 103 164 1 1
PNPLA2 PRPF19 0 0 60 204 1 1
PNPLA2 SMYD1 0 0 0 263 1 1
PNPLA2 PROCA1 0 0 0 163 1 1
PNPLA2 PC 0 0 323 367 1 1
PNPLA2 PPT2 0 0 57 156 1 1
PNPLA2 ULK3 0 0 0 156 1 2
PNPLA2 APEH 0 0 166 242 1 1
PNPLA2 SREBF2 0 0 407 513 1 1
PNPLA2 PPP1R3B 0 0 156 175 1 1
PNPLA2 ALDH2 0 0 113 152 1 2
PNPLA2 ARAP1 0 0 0 211 1 1
PNPLA2 LPGAT1 0 0 64 180 1 1
PNPLA2 IDUA 0 0 0 175 1 1
PNPLA2 AHR 0 0 98 262 1 2
PNPLA2 SERPINE1 0 0 212 291 1 1
PNPLA2 DAGLB 0 0 241 252 1 1
PNPLA2 NCOR1 0 0 205 258 1 1
PNPLA2 ADRB2 0 0 184 206 1 1
PNPLA2 RPS6KB1 0 0 294 299 1 2
PNPLA2 RPS9 0 0 75 194 1 1
PNPLA2 LOX 0 0 258 275 1 2
PNPLA2 IRS1 0 0 469 497 1 2
PNPLA2 ABHD17C 0 0 93 195 1 1
PNPLA2 FADS2 0 0 341 368 1 1
PNPLA2 OSBPL10 0 0 0 154 1 1
PNPLA2 CANX 0 0 234 237 1 2
PNPLA2 FAF2 270 0 892 920 1 1
PNPLA2 ACAT1 0 0 140 292 1 1
PNPLA2 SLC27A4 0 0 416 465 1 1
PNPLA2 TBX1 0 0 155 154 1 1
PNPLA2 PAFAH1B3 0 0 89 195 1 1
PNPLA2 CAT 0 0 275 299 1 2
PNPLA2 CAPN14 0 0 107 185 1 1
PNPLA2 SLC27A1 0 0 651 673 1 1
PNPLA2 TPRKB 0 0 66 209 1 1
PNPLA2 ACOT13 0 0 128 216 1 1
PNPLA2 GPAM 0 0 597 633 1 1
PNPLA2 HPRT1 0 0 211 230 1 1
PNPLA2 SSH3 0 0 0 181 1 1
PNPLA2 ACOT8 0 0 141 173 1 1
PNPLA2 PNPLA6 0 0 469 671 1 1
PNPLA2 ALDH7A1 0 0 150 150 1 1
PNPLA2 PDCD6IP 0 0 0 216 1 1
PNPLA2 ATP13A2 0 0 108 159 1 1
PNPLA2 CES1 0 0 602 609 1 1
PNPLA2 MLYCD 0 0 338 366 1 1
PNPLA2 CNPPD1 0 0 0 198 1 1
PNPLA2 TDRKH 0 0 53 310 1 1
PNPLA2 TNF 0 0 424 448 1 2
PNPLA2 LPIN2 0 650 335 787 1 1
PNPLA2 CLPS 0 0 370 409 1 1
PNPLA2 KANK4 0 0 73 165 1 1
PNPLA2 PLA2G12A 0 0 170 227 1 1
PNPLA2 SCP2 0 0 123 198 1 1
PNPLA2 RAB1B 0 0 66 187 1 2
PNPLA2 UBXN6 0 0 97 201 1 1
PNPLA2 RETN 0 0 427 444 1 1
PNPLA2 MOCOS 0 0 0 173 1 1
PNPLA2 LIPG 0 800 338 861 1 1
PNPLA2 CNR1 0 0 179 179 1 1
PNPLA2 FFAR3 0 0 147 167 1 1
PNPLA2 FABP1 0 0 457 461 1 1
PNPLA2 SLC38A3 0 0 193 200 1 1
PNPLA2 ARNTL 0 0 264 264 1 1
PNPLA2 LIPF 0 800 95 849 1 1
PNPLA2 AGK 0 900 44 900 1 1
PNPLA2 ACSBG2 0 600 123 664 1 1
PNPLA2 GCG 0 0 454 458 1 1
PNPLA2 TCP1 0 0 90 235 1 1
PNPLA2 NFKB2 0 0 0 168 1 1
PNPLA2 AGT 0 0 157 194 1 1
PNPLA2 TXNIP 0 0 193 231 1 2
PNPLA2 RAB7A 0 0 181 186 1 2
PNPLA2 THRSP 0 0 288 315 1 1
PNPLA2 IMPDH1 0 0 0 177 1 1
PNPLA2 ABHD14B 0 0 111 338 1 1
PNPLA2 PEX5 0 0 143 255 1 1
PNPLA2 MAPK8 0 0 166 167 1 2
PNPLA2 CHKA 0 0 134 175 1 1
PNPLA2 GPX4 0 0 193 193 1 2
PNPLA2 MEST 0 0 117 246 1 1
PNPLA2 HSP90B1 0 0 100 189 1 1
PNPLA2 CYP2E1 0 0 182 188 1 2
PNPLA2 PPARA 0 0 841 846 1 2
PNPLA2 CETP 0 0 161 170 1 1
PNPLA2 LPL 0 900 710 970 1 1
PNPLA2 HMGCL 0 0 218 250 1 1
PNPLA2 HSPA4 0 0 142 185 1 1
PNPLA2 ZNF524 0 0 0 151 1 1
PNPLA2 ACSF3 0 0 113 159 1 1
PNPLA2 C17orf78 0 0 0 162 1 1
PNPLA2 TFAP2E 0 0 57 250 1 1
PNPLA2 LPIN3 0 650 277 768 1 1
PNPLA2 IGFBP1 0 0 108 177 1 1
PNPLA2 HNF1A 0 0 125 160 1 1
PNPLA2 LIPJ 0 0 193 343 1 1
PNPLA2 HSD17B13 0 0 195 201 1 1
PNPLA2 AIFM2 0 0 94 195 1 1
PNPLA2 SLC27A5 0 0 332 359 1 1
PNPLA2 CYCS 0 0 266 292 1 2
PNPLA2 DGKZ 0 650 45 685 1 1
PNPLA2 ELOVL1 0 0 181 279 1 1
PNPLA2 PPAPDC1B 0 650 66 718 1 1
PNPLA2 CRY2 0 0 124 237 1 1
PNPLA2 SERPINF1 486 0 734 860 1 1
PNPLA2 ADIPOR1 0 0 325 408 1 1
PNPLA2 ACSS1 0 0 249 286 1 1
PNPLA2 ADRA2A 0 0 48 212 1 1
PNPLA2 PKLR 0 0 161 195 1 1
PNPLA2 SCARB1 0 0 262 308 1 1
PNPLA2 CREB3L3 0 0 265 326 1 1
PNPLA2 CD68 0 0 261 280 1 2
PNPLA2 ALB 0 0 459 501 1 2
PNPLA2 CCL2 0 0 391 390 1 2
PNPLA2 CHSY1 0 0 0 161 1 1
PNPLA2 PDAP1 0 0 67 161 1 1
PNPLA2 FNDC5 0 0 334 334 1 1
PNPLA2 EPM2A 0 0 0 151 1 2
PNPLA2 RAB32 0 0 193 249 1 2
PNPLA2 NRG4 0 0 125 161 1 1
PNPLA2 NSDHL 0 0 181 244 1 1
PNPLA2 MOGAT3 0 650 181 712 1 1
PNPLA2 ALDH3A2 0 0 158 249 1 1
PNPLA2 PLA2G16 0 0 296 296 1 1
PNPLA2 DUSP8 0 0 66 294 1 1
PNPLA2 SIRT6 0 0 246 290 1 2
PNPLA2 PYY 0 0 151 150 1 1
PNPLA2 FABP5 0 0 324 356 1 1
PNPLA2 DUSP16 0 0 0 247 1 1
PNPLA2 NR1D2 0 0 125 179 1 1
PNPLA2 CDKN1A 0 0 71 171 1 2
PNPLA2 LDLRAP1 0 0 107 336 1 1
PNPLA2 EHHADH 0 0 368 386 1 1
PNPLA2 TST 0 0 82 164 1 1
PNPLA2 XKR8 0 0 69 244 1 1
PNPLA2 ZBTB7B 0 0 0 183 1 1
PNPLA2 GPIHBP1 0 0 252 268 1 1
PNPLA2 UBE2G2 0 0 141 159 1 1
PNPLA2 CRP 0 0 235 235 1 2
PNPLA2 NPEPL1 0 0 0 289 1 1
PNPLA2 ACSBG1 0 600 72 645 1 1
PNPLA2 HDAC4 0 0 125 173 1 2
PNPLA2 HSP90AA1 0 0 193 210 1 2
PNPLA2 LASP1 0 0 0 163 1 1
PNPLA2 SPG20 0 0 169 180 1 1
PNPLA2 SQSTM1 0 0 212 240 1 2
PNPLA2 KIFC2 0 0 0 151 1 1
PNPLA2 JUNB 0 0 0 303 1 1
PNPLA2 PCK2 0 0 406 445 1 1
PNPLA2 PNPLA5 0 0 558 160 1 1
PNPLA2 ABCG1 0 0 206 223 1 2
PNPLA2 MAPK3 0 0 278 304 1 2
PNPLA2 KLF15 0 0 210 235 1 1
PNPLA2 ACSS3 0 0 143 166 1 1
PNPLA2 SLC7A3 0 0 45 192 1 1
PNPLA2 PCYOX1 0 0 66 232 1 1
PNPLA2 UBALD1 0 0 0 165 1 1
PNPLA2 GNA14 0 0 0 189 1 1
PNPLA2 DHRS11 0 0 120 280 1 1
PNPLA2 SIK2 0 0 171 220 1 1
PNPLA2 COL18A1 0 0 113 217 1 1
PNPLA2 PAPL 0 0 0 159 1 1
PNPLA2 DGKQ 0 650 57 690 1 1
PNPLA2 TEX2 0 0 0 188 1 1
PNPLA2 CYP7A1 0 0 266 297 1 1
PNPLA2 CRTC3 0 0 183 240 1 1
PNPLA2 UBXN4 0 0 145 192 1 1
PNPLA2 JUN 0 0 232 260 1 2
PNPLA2 ACSF2 0 0 0 185 1 1
PNPLA2 FABP3 0 0 421 449 1 1
PNPLA2 AMFR 0 0 135 153 1 1
PNPLA2 TBC1D4 0 0 372 385 1 1
PNPLA2 ELOVL6 0 0 468 512 1 1
PNPLA2 TTPA 0 0 0 220 1 1
PNPLA2 AZGP1 0 0 456 460 1 1
PNPLA2 CELA3A 0 0 61 157 1 1
PNPLA2 UBXN8 0 0 240 313 1 1
PNPLA2 DOCK9 0 0 45 252 1 1
PNPLA2 INSIG2 0 0 233 247 1 1
PNPLA2 AGPAT1 0 0 421 460 1 1
PNPLA2 SERGEF 0 0 95 159 1 1
PNPLA2 PLA2G15 0 0 232 350 1 1
PNPLA2 SERTAD2 0 0 143 174 1 1
PNPLA2 SLC27A6 0 0 609 625 1 1
PNPLA2 QRSL1 0 0 54 159 1 1
PNPLA2 PRKACB 0 0 0 164 1 1
PNPLA2 AWAT1 0 0 561 577 1 1
PNPLA2 NEK5 0 0 73 481 1 1
PNPLA2 IRS2 0 0 342 358 1 1
PNPLA2 EPHX4 0 0 47 168 1 1
PNPLA2 SIRT2 0 0 244 243 1 2
PNPLA2 SC5D 0 0 141 164 1 1
PNPLA2 METRN 0 0 181 210 1 1
PNPLA2 PPAPDC1A 0 650 63 717 1 1
PNPLA2 LPCAT1 0 0 334 388 1 1
PNPLA2 FTO 0 0 155 285 1 2
PNPLA2 PLA2G2E 0 0 203 217 1 1
PNPLA2 INPPL1 0 0 0 170 1 1
PNPLA2 ODF3L2 0 0 108 181 1 1
PNPLA2 ALDH3B2 0 0 85 159 1 1
PNPLA2 HSD11B1 0 0 267 299 1 1
PNPLA2 ABHD14A 0 0 54 175 1 1
PNPLA2 G0S2 270 0 745 951 1 1
PNPLA2 CREB1 0 0 322 347 1 2
PNPLA2 PCTP 0 0 124 184 1 1
PNPLA2 AKR1B10 0 0 66 163 1 1
PNPLA2 ESRRA 0 0 315 365 1 1
PNPLA2 SDHB 0 0 159 158 1 1
PNPLA2 PFKFB3 0 0 139 184 1 2
PNPLA2 HCAR2 0 0 224 224 1 1
PNPLA2 FKBP8 0 0 81 347 1 1
PNPLA2 TCF7L2 0 0 103 159 1 1
PNPLA2 HDAC10 0 0 0 187 1 1
PNPLA2 CCM2L 0 0 54 165 1 1
PNPLA2 METRNL 0 0 117 169 1 1
PNPLA2 GAPDH 0 0 468 468 1 2
PNPLA2 ELOVL5 0 0 337 352 1 1
PNPLA2 MBOAT2 0 0 294 309 1 1
PNPLA2 NFKB1 0 0 51 172 1 2
PNPLA2 NPR1 0 0 144 191 1 1
PNPLA2 KLK15 0 0 358 358 1 1
PNPLA2 GNRHR 0 0 0 215 1 1
PNPLA2 ZIC1 0 0 113 207 1 1
PNPLA2 OSBPL3 0 0 0 219 1 1
PNPLA2 RDH10 0 0 134 164 1 1
PNPLA2 MYF5 0 0 211 211 1 1
PNPLA2 CTNNB1 0 0 164 163 1 2
PNPLA2 DCAF6 0 0 77 191 1 1
PNPLA2 EGR1 0 0 201 201 1 2
PNPLA2 MFN2 0 0 208 231 1 2
PNPLA2 CXCL8 0 0 171 171 1 2
PNPLA2 NDRG1 0 0 60 154 1 1
PNPLA2 UQCRC2 0 0 166 184 1 1
PNPLA2 NR1H3 0 0 334 408 1 1
PNPLA2 MTMR7 0 0 0 217 1 1
PNPLA2 XKR5 0 0 0 185 1 1
PNPLA2 RPL32 0 0 90 189 1 1
PNPLA2 PDS5B 0 0 0 303 1 1
PNPLA2 ALDH3B1 0 0 0 194 1 1
PNPLA2 PIK3C3 0 0 161 181 1 2
PNPLA2 PLIN1 0 0 964 967 1 1
PNPLA2 TBL1XR1 0 0 87 150 1 1
PNPLA2 EPHX2 0 0 74 195 1 1
PNPLA2 HILPDA 0 0 394 394 1 1
PNPLA2 MTOR 0 0 378 396 1 2
PNPLA2 DGKK 0 650 0 650 1 1
PNPLA2 RNF10 0 0 63 158 1 1
PNPLA2 PLA2G4E 0 0 0 211 1 1
PNPLA2 NCOR2 0 0 85 219 1 1
PNPLA2 DDHD2 0 0 170 253 1 1
PNPLA2 SLC2A1 0 0 395 394 1 2
PNPLA2 OSBPL5 0 0 0 154 1 1
PNPLA2 LAMP1 0 0 193 222 1 2
PNPLA2 TSC22D4 0 0 0 159 1 1
PNPLA2 EGFR 130 0 102 185 1 2
PNPLA2 ALOX15 0 0 250 250 1 1
PNPLA2 TP53 0 0 218 218 1 2
PNPLA2 LCN2 0 0 160 178 1 1
PNPLA2 HMGCS1 0 0 242 259 1 1
PNPLA2 DGKH 0 650 61 678 1 1
PNPLA2 INSIG1 0 0 227 309 1 1
PNPLA2 NR1H2 0 0 0 215 1 1
PNPLA2 CD300C 0 0 182 181 1 1
PNPLA2 EML2 0 0 64 286 1 1
PNPLA2 PMVK 0 0 90 177 1 1
PNPLA2 MYH6 0 0 205 205 1 1
PNPLA2 PCYT2 0 0 242 299 1 1
PNPLA2 PPARD 0 0 447 566 1 1
PNPLA2 PLA2G4C 0 0 261 278 1 1
PNPLA2 ABHD2 0 0 128 508 1 1
PNPLA2 GHRL 0 0 235 235 1 1
PNPLA2 JAK2 0 0 138 154 1 2
PNPLA2 GBF1 270 0 454 613 1 1
PNPLA2 ABHD8 0 0 49 224 1 1
PNPLA2 PNLIPRP3 0 800 0 903 1 1
PNPLA2 PPAP2B 0 650 103 679 1 1
PNPLA2 GFRAL 0 0 149 168 1 1
PNPLA2 HNF4G 0 0 0 224 1 1
PNPLA2 P4HB 0 0 167 209 1 2
PNPLA2 RICTOR 0 0 203 203 1 2
PNPLA2 SOAT2 0 0 46 164 1 1
PNPLA2 G6PC 0 0 460 471 1 1
PNPLA2 DVL1 0 0 0 150 1 1
PNPLA2 FA2H 0 0 193 213 1 1
PNPLA2 PCK1 0 0 495 528 1 1
PNPLA2 PPARGC1A 0 0 682 684 1 2
PNPLA2 ELMOD2 0 0 217 217 1 1
PNPLA2 PPRC1 0 0 108 172 1 1
PNPLA2 DGAT1 0 650 759 936 1 2
PNPLA2 CBX5 0 0 0 192 1 1
PNPLA2 CLOCK 0 0 134 166 1 2
PNPLA2 NR0B2 0 0 155 154 1 1
PNPLA2 STK11 0 0 233 340 1 2
PNPLA2 TMEM69 0 0 113 504 1 1
PNPLA2 PNLIPRP1 0 800 108 857 1 1
PNPLA2 ZNF865 0 0 0 214 1 1
PNPLA2 SLC25A19 0 0 240 239 1 1
PNPLA2 MLPH 0 0 44 152 1 1
PNPLA2 LMF2 0 0 93 206 1 1
PNPLA2 EBF2 0 0 160 159 1 1
PNPLA2 GOLPH3 0 0 426 426 1 1
PNPLA2 MKNK2 0 0 0 166 1 1
PNPLA2 SOAT1 0 0 159 234 1 1
PNPLA2 RIMS4 0 0 57 225 1 1
PNPLA2 OVCA2 0 0 113 249 1 1
PNPLA2 CERS3 0 0 117 221 1 1
PNPLA2 KLF16 0 0 61 169 1 1
PNPLA2 EPHX3 0 0 66 185 1 1
PNPLA2 HSPB1 0 0 0 170 1 2
PNPLA2 RBBP9 0 0 107 201 1 1
PNPLA2 MGLL 0 900 823 983 1 1
PNPLA2 XKRX 0 0 0 156 1 1
PNPLA2 NDUFB8 0 0 167 168 1 1
PNPLA2 FAM229A 0 0 0 156 1 1
PNPLA2 AADAC 0 0 394 517 1 1
PNPLA2 ABHD16B 0 0 70 180 1 1
PNPLA2 ATG5 0 0 278 298 1 2
PNPLA2 NCEH1 0 0 245 320 1 1
PNPLA2 XBP1 0 0 211 265 1 2
PNPLA2 PTPN1 0 0 140 155 1 1
PNPLA2 FUS 0 0 74 240 1 2
PNPLA2 PECR 0 0 155 236 1 1
PNPLA2 ACOX1 0 0 601 624 1 1
PNPLA2 MGAT1 0 0 345 391 1 1
PNPLA2 DLK1 0 0 154 153 1 1
PNPLA2 SIRT1 0 0 508 514 1 2
PNPLA2 ECI1 0 0 113 171 1 1
PNPLA2 DCP1B 0 0 66 182 1 1
PNPLA2 PPAP2A 0 0 213 349 1 1
PNPLA2 ITGAM 0 0 174 194 1 1
PNPLA2 DGKA 0 650 57 665 1 1
PNPLA2 PTRF 0 0 134 212 1 1
PNPLA2 NFKBIA 0 0 157 188 1 2
PNPLA2 LEP 0 0 652 667 1 1
PNPLA2 MAPK14 0 0 108 162 1 2
PNPLA2 GPD2 0 0 112 193 1 1
PNPLA2 SREBF1 0 0 718 780 1 1
PNPLA2 FAM134B 0 0 317 317 1 1
PNPLA2 UCP1 0 0 720 727 1 2
PNPLA2 VEGFA 0 0 435 435 1 2
PNPLA2 PTEN 0 0 176 194 1 2
PNPLA2 DNM1L 0 0 142 163 1 2
PNPLA2 PANK2 0 0 240 239 1 1
PNPLA2 PLA2G5 0 0 325 337 1 1
PNPLA2 DDHD1 0 0 157 231 1 1
PNPLA2 PRKAA2 0 0 123 388 1 2
PNPLA2 SAP30BP 0 0 0 154 1 1
PNPLA2 FFAR4 0 0 282 294 1 1
PNPLA2 PRSS27 0 0 72 164 1 1
PNPLA2 ATG7 0 0 324 355 1 2
PNPLA2 BTG2 0 0 0 214 1 1
PNPLA2 ACTG1 0 0 171 209 1 1
PNPLA2 CPT1C 0 0 510 517 1 1
PNPLA2 NAMPT 0 0 279 294 1 2
PNPLA2 PPARGC1B 0 0 266 294 1 1
PNPLA2 COL1A1 0 0 157 171 1 2
PNPLA2 CTSD 0 0 96 189 1 2
PNPLA2 TRIM63 0 0 226 225 1 1
PNPLA2 GPR132 0 0 181 181 1 1
PNPLA2 LCLAT1 0 0 218 353 1 1
PNPLA2 G6PD 0 0 207 262 1 1
PNPLA2 SIK3 0 0 202 287 1 1
PNPLA2 LCAT 0 0 122 182 1 1
PNPLA2 AGRP 0 0 282 303 1 1
PNPLA2 BPHL 0 0 145 358 1 1
PNPLA2 ICT1 0 0 150 181 1 1
PNPLA2 USF2 0 0 57 152 1 1
PNPLA2 ARFGAP1 0 0 87 152 1 1
PNPLA2 DLAT 0 0 94 159 1 1
PNPLA2 ANGPTL3 0 0 154 231 1 1
PNPLA2 KLF2 0 0 91 161 1 1
PNPLA2 PDE3B 0 0 556 573 1 1
PNPLA2 EHBP1L1 0 0 0 155 1 1
PNPLA2 GK 0 0 460 471 1 1
PNPLA2 FABP4 0 0 685 711 1 1
PNPLA2 TBC1D1 0 0 212 226 1 1
PNPLA2 ITGAX 0 0 181 181 1 1
PNPLA2 LIPK 0 0 73 191 1 1
PNPLA2 SLC35D3 0 0 67 280 1 1
PNPLA2 AKAP1 0 0 135 165 1 1
PNPLA2 TFB2M 0 0 138 171 1 1
PNPLA2 FBP1 0 0 134 170 1 1
PNPLA2 CDC27 0 0 0 154 1 1
PNPLA2 LIPC 0 800 629 925 1 1
PNPLA2 RPSA 0 0 566 577 1 1
PNPLA2 PLIN3 0 0 776 788 1 1
PNPLA2 TNN 0 0 0 291 1 1
PNPLA2 LPCAT4 0 0 142 192 1 1
PNPLA2 DBI 0 0 143 215 1 1
PNPLA2 PPIA 0 0 279 302 1 1
PNPLA2 CPPED1 0 0 0 159 1 1
PNPLA2 PNPLA8 0 0 830 839 1 1
PNPLA2 PFDN4 0 0 0 167 1 1
PNPLA2 ALOX5 130 0 244 335 1 1
PNPLA2 ATG12 0 0 141 156 1 2
PNPLA2 SLC27A3 0 0 160 199 1 1
PNPLA2 EHD2 0 0 93 174 1 1
PNPLA2 STS 0 0 306 320 1 1
PNPLA2 SLC5A2 0 0 143 175 1 1
PNPLA2 ABHD11 0 0 181 312 1 1
PNPLA2 MTMR12 0 0 0 158 1 1
PNPLA2 FAM213B 0 0 66 162 1 1
PNPLA2 PLXDC1 0 0 154 153 1 1
PNPLA2 UGP2 0 0 43 161 1 1
PNPLA2 DGKE 0 650 89 674 1 1
PNPLA2 PISD 0 0 113 174 1 1
PNPLA2 OSBPL11 0 0 0 200 1 1
PNPLA2 ANGPTL4 0 0 403 416 1 1
PNPLA2 AGPAT6 0 0 564 589 1 1
PNPLA2 MSTN 0 0 262 263 1 1
PNPLA2 METTL7B 0 0 181 199 1 1
PNPLA2 YWHAZ 0 0 101 223 1 1
PNPLA2 MAT1A 0 0 71 185 1 1
PNPLA2 DGKD 0 650 171 716 1 1
PNPLA2 PNPLA7 0 0 211 506 1 1
PNPLA2 ACAT2 0 0 160 247 1 1
PNPLA2 FAM200B 0 0 202 202 1 1
PNPLA2 FOXO1 0 0 573 583 1 2
PNPLA2 PGD 0 0 261 261 1 1
PNPLA2 SOD2 0 0 184 183 1 2
PNPLA2 HSPA5 0 0 218 266 1 2
PNPLA2 TFE3 0 0 162 261 1 2
PNPLA2 SERHL2 0 0 65 184 1 1
PNPLA2 LGALS12 0 0 248 303 1 1
PNPLA2 TMEM163 0 0 0 183 1 1
PNPLA2 TH 0 0 162 161 1 2
PNPLA2 KAL1 0 0 297 297 1 1
PNPLA2 BCO1 0 0 113 200 1 1
PNPLA2 FAAH 0 0 171 250 1 1
PNPLA2 PINK1 0 0 157 207 1 2
PNPLA2 CERS4 0 0 95 205 1 1
PNPLA2 TMEM86B 0 0 170 236 1 1
PNPLA2 RALY 0 0 0 195 1 1
PNPLA2 GPT 0 0 391 439 1 1
PNPLA2 BMP8B 0 0 193 210 1 1
PNPLA2 SDR16C5 0 0 0 227 1 1
PNPLA2 BSCL2 0 0 459 548 1 1
PNPLA2 PMS2 0 0 0 282 1 1
PNPLA2 EIF4EBP1 0 0 218 222 1 2
PNPLA2 FOXO4 0 0 123 219 1 1
PNPLA2 PTPN23 0 0 0 190 1 1
PNPLA2 ACACB 0 0 457 518 1 1
PNPLA2 DGKG 0 650 0 655 1 1
PNPLA2 ABHD15 0 0 243 273 1 1
PNPLA2 PLXDC2 0 0 151 150 1 1
PNPLA2 ARF4 0 0 160 216 1 1
PNPLA2 ECHS1 0 0 150 208 1 1
PNPLA2 GTF2A1 0 0 62 152 1 1
PNPLA2 CPT1A 0 0 662 682 1 1
PNPLA2 MBTPS1 0 0 45 191 1 1
PNPLA2 WDTC1 0 0 0 237 1 1
PNPLA2 VDAC1 0 0 157 176 1 2
PNPLA2 RAB7B 0 0 171 188 1 1
PNPLA2 LOC388210 0 0 0 153 1 1
PNPLA2 ISX 0 0 57 189 1 1
PNPLA2 DIO2 0 0 469 476 1 1
PNPLA2 HYAL1 0 0 0 210 1 1
PNPLA2 PARP10 0 0 0 165 1 1
PNPLA2 OXCT1 0 0 163 163 1 1
PNPLA2 ADIPOR2 0 0 335 381 1 1
PNPLA2 RARRES2 0 0 193 210 1 1
PNPLA2 SLC13A2 0 0 94 150 1 1
PNPLA2 LYPLA2 0 0 138 178 1 1
PNPLA2 ECH1 0 0 181 200 1 1
PNPLA2 ATG3 0 0 134 155 1 2
PNPLA2 PREPL 0 0 82 187 1 1
PNPLA2 RNPEPL1 0 0 0 196 1 1
PNPLA2 FADS3 0 0 135 154 1 1
PNPLA2 HNF4A 0 0 181 337 1 1
PNPLA2 FOXO3 0 0 235 414 1 2
PNPLA2 SLC2A4 0 0 653 669 1 1
PNPLA2 APOE 0 0 295 324 1 2
PNPLA2 CRY1 0 0 195 215 1 1
PNPLA2 AFMID 0 0 72 244 1 1
PNPLA2 CRAT 0 0 161 230 1 1
PNPLA2 SORBS1 0 0 66 180 1 1
PNPLA2 MRPS33 0 0 0 296 1 1
PNPLA2 CD36 0 0 517 557 1 2
PNPLA2 ACOT7 0 0 154 187 1 1
PNPLA2 NOS3 0 0 161 179 1 2
PNPLA2 PRKAA1 0 0 96 369 1 2
PNPLA2 RFWD2 270 0 107 385 1 1
PNPLA2 PCYT1B 0 0 180 262 1 1
PNPLA2 HMGCR 0 0 377 390 1 1
PNPLA2 LIPA 0 0 561 642 1 1
PNPLA2 FADS1 0 0 282 298 1 1
PNPLA2 LRP6 0 0 279 295 1 1
PNPLA2 AGPAT3 0 0 321 444 1 1
PNPLA2 ABCG5 0 0 181 198 1 1
PNPLA2 NDUFB5 0 0 77 185 1 1
PNPLA2 INF2 0 0 0 157 1 1
PNPLA2 HTRA4 0 0 59 177 1 1
PNPLA2 EFNA1 0 0 0 190 1 1
PNPLA2 KLF9 0 0 113 193 1 1
PNPLA2 DHRS3 0 0 113 192 1 1
PNPLA2 LDLR 0 0 334 351 1 2
PNPLA2 DFFA 0 0 348 354 1 1
PNPLA2 LPCAT3 0 0 292 307 1 1
PNPLA2 CYP4F22 0 0 167 201 1 1
PNPLA2 NR1D1 0 0 256 300 1 2
PNPLA2 SIDT1 0 0 54 155 1 1
PNPLA2 RHEB 0 0 156 155 1 2
PNPLA2 FDFT1 0 0 173 173 1 1
PNPLA2 NRIP1 0 0 282 282 1 1
PNPLA2 DAGLA 0 0 242 276 1 1
PNPLA2 PLA2G4D 0 0 117 205 1 1
PNPLA2 ACADM 0 0 502 512 1 1
PNPLA2 SMPD2 0 0 122 212 1 1
PNPLA2 RPLP0 0 0 134 245 1 1
PNPLA2 MRGPRX3 0 0 81 227 1 1
PNPLA2 ABHD17A 0 0 81 252 1 1
PNPLA2 XDH 0 0 140 181 1 1
PNPLA2 C19orf80 0 0 260 273 1 1
PNPLA2 FAXDC2 0 0 74 246 1 1
PNPLA2 ABHD10 0 0 173 305 1 1
PNPLA2 RBM7 0 0 57 157 1 1
PNPLA2 PLA2G2A 0 0 500 509 1 1
PNPLA2 ELOVL7 0 0 181 221 1 1
PNPLA2 ABHD6 0 0 292 414 1 1
PNPLA2 IP6K1 0 0 108 160 1 1
PNPLA2 UCP3 0 0 469 492 1 1
PNPLA2 ABHD5 651 800 991 999 1 1
PNPLA2 VPS51 0 0 60 276 1 1
PNPLA2 BDNF 0 0 150 177 1 2
PNPLA2 UBAC2 0 0 181 181 1 1
PNPLA2 PKM 0 0 120 163 1 1
PNPLA2 MTFR1 0 0 138 177 1 1
PNPLA2 PLA2G3 0 0 146 164 1 1
PNPLA2 APOB 0 0 583 596 1 2
PNPLA2 ALDH9A1 0 0 91 179 1 1
PNPLA2 IGF1 0 0 316 315 1 2
PNPLA2 MAPK1 0 0 92 165 1 2
PNPLA2 ANAPC2 0 0 0 183 1 1
PNPLA2 EDEM1 0 0 57 157 1 2
PNPLA2 DHRS1 0 0 122 214 1 1
PNPLA2 APOC3 0 0 263 273 1 1
PNPLA2 CYB5R3 0 0 116 164 1 1
PNPLA2 SEC23IP 0 0 74 166 1 1
PNPLA2 BCL2A1 0 0 260 276 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0016411 Molecular Function acylglycerol O-acyltransferase activity enables IDA
GO:0016411 Molecular Function acylglycerol O-acyltransferase activity enables TAS
GO:0051265 Molecular Function diolein transacylation activity enables IDA
GO:0004465 Molecular Function lipoprotein lipase activity enables TAS
GO:0051264 Molecular Function mono-olein transacylation activity enables IDA
GO:0004623 Molecular Function phospholipase A2 activity enables IDA
GO:0005515 Molecular Function protein binding enables IPI
GO:0050253 Molecular Function retinyl-palmitate esterase activity enables EXP
GO:0004806 Molecular Function triglyceride lipase activity enables EXP
GO:0004806 Molecular Function triglyceride lipase activity enables IBA
GO:0004806 Molecular Function triglyceride lipase activity enables IDA
GO:0004806 Molecular Function triglyceride lipase activity enables IMP
GO:0004806 Molecular Function triglyceride lipase activity enables ISS
GO:0004806 Molecular Function triglyceride lipase activity enables TAS
GO:0036155 Biological Process acylglycerol acyl-chain remodeling involved_in TAS
GO:0006651 Biological Process diacylglycerol biosynthetic process involved_in ISS
GO:1905691 Biological Process lipid droplet disassembly involved_in IMP
GO:0055088 Biological Process lipid homeostasis involved_in IBA
GO:0019915 Biological Process lipid storage involved_in IEA
GO:0010891 Biological Process negative regulation of sequestering of triglyceride involved_in IDA
GO:0010898 Biological Process positive regulation of triglyceride catabolic process involved_in IDA
GO:0042572 Biological Process retinol metabolic process involved_in IEA
GO:0019433 Biological Process triglyceride catabolic process involved_in IBA
GO:0019433 Biological Process triglyceride catabolic process involved_in IEA
GO:0019433 Biological Process triglyceride catabolic process involved_in ISS
GO:0005737 Cellular Component cytoplasm is_active_in IBA
GO:0005737 Cellular Component cytoplasm located_in ISS
GO:0005829 Cellular Component cytosol located_in IEA
GO:0005788 Cellular Component endoplasmic reticulum lumen located_in TAS
GO:0005789 Cellular Component endoplasmic reticulum membrane located_in TAS
GO:0005811 Cellular Component lipid droplet is_active_in IBA
GO:0005811 Cellular Component lipid droplet is_active_in IDA
GO:0005811 Cellular Component lipid droplet located_in IDA
GO:0016020 Cellular Component membrane is_active_in IBA
GO:0005654 Cellular Component nucleoplasm located_in IDA
GO:0005886 Cellular Component plasma membrane located_in IDA
Pathways
Name DB ID
Metabolism Reactome R-HSA-1430728
Acyl chain remodeling of DAG and TAG Reactome R-HSA-1482883
Glycerophospholipid biosynthesis Reactome R-HSA-1483206
Phospholipid metabolism Reactome R-HSA-1483257
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Reactome R-HSA-381426
Metabolism of proteins Reactome R-HSA-392499
Metabolism of lipids Reactome R-HSA-556833
Post-translational protein modification Reactome R-HSA-597592
Post-translational protein phosphorylation Reactome R-HSA-8957275
Thermogenesis (WP4321) WikiPathways WP4321_r123362
Thyroid hormones production and peripheral downstream signaling effects (WP4746) WikiPathways WP4746_r123317
Lipid metabolism pathway (WP3965) WikiPathways WP3965_r117154
Familial partial lipodystrophy (WP5102) WikiPathways WP5102_r123632
Fatty acid beta-oxidation (WP143) WikiPathways WP143_r116506
Triacylglyceride synthesis (WP325) WikiPathways WP325_r123953
Glycerolipids and glycerophospholipids (WP4722) WikiPathways WP4722_r124748
Transcripts
Accession Version MolecularType Name NCBI Comments
NM_020376 4 mRNA None NC_000011 Reference