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MAVS

mitochondrial antiviral signaling protein
General Information
Name mitochondrial antiviral signaling protein
Alias
  • mitochondrial antiviral-signaling protein
  • CARD adapter inducing interferon beta
  • CARD adaptor inducing IFN-beta
  • IFN-B promoter stimulator 1
  • interferon beta promoter stimulator protein 1
  • putative NF-kappa-B-activating protein 031N
  • virus-induced signaling adaptor
  • virus-induced-signaling adapter
Gene_family Caspase recruitment domain containing
organism Homo sapiens
entrez_id 57506
location 20p13
transcript_count 4
exon_count 8
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez This gene encodes an intermediary protein necessary in the virus-triggered beta interferon signaling pathways. It is required for activation of transcription factors which regulate expression of beta interferon and contributes to antiviral innate immunity. [provided by RefSeq, Jul 2020]
    Stringdb Mitochondrial antiviral-signaling protein; Required for innate immune defense against viruses. Acts downstream of DDX58/RIG-I and IFIH1/MDA5, which detect intracellular dsRNA produced during viral replication, to coordinate pathways leading to the activation of NF-kappa-B, IRF3 and IRF7, and to the subsequent induction of antiviral cytokines such as IFN-beta and RANTES (CCL5). Peroxisomal and mitochondrial MAVS act sequentially to create an antiviral cellular state. Upon viral infection, peroxisomal MAVS induces the rapid interferon- independent expression of defense factors that provi [...]
    nextProt Required for innate immune defense against viruses (PubMed:16125763, PubMed:16127453, PubMed:16153868, PubMed:16177806, PubMed:19631370, PubMed:20451243, PubMed:23087404, PubMed:20127681, PubMed:21170385). Acts downstream of DHX33, RIGI and IFIH1/MDA5, which detect intracellular dsRNA produced during viral replication, to coordinate pathways leading to the activation of NF-kappa-B, IRF3 and IRF7, and to the subsequent induction of antiviral cytokines such as IFNB and RANTES (CCL5) (PubMed:16125763, PubMed:16127453, PubMed:16153868, PubMed:16177806, PubMed:19631370, PubMed:20451243, PubMed:23087404, PubMed:25636800, PubMed:20127681, PubMed:21170385, PubMed:20628368, PubMed:33110251, PubMed:27736772). Peroxisomal and mitochondrial MAVS act sequentially to create an antiviral cellular state (PubMed:20451243). Upon viral infection, peroxisomal MAVS induces the rapid interferon-independent expression of defense factors that provide short-term protection, whereas mitochondrial MAVS activates an interferon-dependent signaling pathway with delayed kinetics, which amplifies and stabilizes the antiviral response (PubMed:20451243). May activate the same pathways following detection of extracellular dsRNA by TLR3 (PubMed:16153868). May protect cells from apoptosis (PubMed:16125763).
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
MAVS BioGRID ORF6 GeneID BioGRID Proximity Label-MS
MAVS BioGRID Rab18 GeneID BioGRID Proximity Label-MS
MAVS BioGRID USP35 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
MAVS BioGRID RAB11A GeneID BioGRID Proximity Label-MS
MAVS BioGRID RAB25 GeneID BioGRID Proximity Label-MS
MAVS BioGRID RAB4A GeneID BioGRID Proximity Label-MS
MAVS BioGRID TRIM67 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID RIGI GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
MAVS BioGRID IKBKE GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
MAVS BioGRID TRAF2 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Proximity Label-MS; Two-hybrid
MAVS BioGRID FGFR3 GeneID BioGRID Proximity Label-MS
MAVS BioGRID CCNF GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
MAVS BioGRID BAG6 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Proximity Label-MS; Reconstituted Complex
MAVS BioGRID TRAF6 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-crystal Structure; Reconstituted Complex
MAVS BioGRID TRAF5 GeneID BioGRID Affinity Capture-Western; Two-hybrid
MAVS BioGRID TRAF3 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
MAVS BioGRID ORF7b GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Two-hybrid
MAVS BioGRID N GeneID BioGRID Affinity Capture-Western
MAVS BioGRID TBK1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity
MAVS BioGRID TRIM31 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
MAVS BioGRID FHIP2B GeneID BioGRID Proximity Label-MS
MAVS BioGRID ORF10 GeneID BioGRID Proximity Label-MS
MAVS BioGRID ORF1ab GeneID BioGRID Proximity Label-MS
MAVS BioGRID ORF1ab GeneID BioGRID Proximity Label-MS
MAVS BioGRID ORF1ab GeneID BioGRID Proximity Label-MS
MAVS BioGRID ORF1ab GeneID BioGRID Proximity Label-MS
MAVS BioGRID ORF1ab GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Proximity Label-MS
MAVS BioGRID ORF1ab GeneID BioGRID Proximity Label-MS
MAVS BioGRID ORF1ab GeneID BioGRID Proximity Label-MS
MAVS BioGRID SBK2 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID sars9b GeneID BioGRID Affinity Capture-Western; Co-localization
MAVS BioGRID S GeneID BioGRID Affinity Capture-MS
MAVS BioGRID ZRANB1 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID PCBP2 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID HSPA1A GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
MAVS BioGRID ITCH GeneID BioGRID Affinity Capture-Western
MAVS BioGRID RNF146 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID TNKS2 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
MAVS BioGRID NLRX1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
MAVS BioGRID SMURF1 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID STK26 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID TNKS GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity
MAVS BioGRID RUVBL1 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID PLK1 GeneID BioGRID Affinity Capture-MS; Proximity Label-MS; Two-hybrid
MAVS BioGRID PCBP1 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID OPA1 GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
MAVS BioGRID GNB1 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID ARL1 GeneID BioGRID Proximity Label-MS
MAVS BioGRID ARL10 GeneID BioGRID Proximity Label-MS
MAVS BioGRID ARL5B GeneID BioGRID Proximity Label-MS
MAVS BioGRID SAR1A GeneID BioGRID Proximity Label-MS
MAVS BioGRID ARL8B GeneID BioGRID Proximity Label-MS
MAVS BioGRID SAR1B GeneID BioGRID Proximity Label-MS
MAVS BioGRID ARL5A GeneID BioGRID Proximity Label-MS
MAVS BioGRID ARFRP1 GeneID BioGRID Proximity Label-MS
MAVS BioGRID DHX16 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID SGTA GeneID BioGRID Affinity Capture-Western; Proximity Label-MS; Reconstituted Complex
MAVS BioGRID RNF5 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
MAVS BioGRID REC8 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID NUP43 GeneID BioGRID Proximity Label-MS
MAVS BioGRID SOX9 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID USP25 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
MAVS BioGRID CNTN1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
MAVS BioGRID SERINC5 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID MARCHF5 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Proximity Label-MS
MAVS BioGRID MAP4K1 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID N4BP3 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID MAVS GeneID BioGRID Affinity Capture-Western; Co-fractionation; Reconstituted Complex; Two-hybrid
MAVS BioGRID PML GeneID BioGRID Proximity Label-MS
MAVS BioGRID RAB7A GeneID BioGRID Proximity Label-MS
MAVS BioGRID RND2 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID MCCC1 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID RHOD GeneID BioGRID Affinity Capture-MS
MAVS BioGRID RAC3 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID RAC2 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID CDC42 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID RHOH GeneID BioGRID Affinity Capture-MS
MAVS BioGRID RHOG GeneID BioGRID Affinity Capture-MS
MAVS BioGRID RHOA GeneID BioGRID Affinity Capture-MS
MAVS BioGRID EIF2AK2 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
MAVS BioGRID USP18 GeneID BioGRID Affinity Capture-Western; Co-localization
MAVS BioGRID DUT GeneID BioGRID Affinity Capture-Western
MAVS BioGRID ATG12 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID ATG5 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID INSC GeneID BioGRID Affinity Capture-MS
MAVS BioGRID PIPSL GeneID BioGRID Affinity Capture-MS
MAVS BioGRID SLC39A12 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID ADGRF3 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID NXPE2 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID TMEM169 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID NAA40 GeneID BioGRID Proximity Label-MS
MAVS BioGRID IFIH1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
MAVS BioGRID SPPL2B GeneID BioGRID Affinity Capture-MS
MAVS BioGRID VAC14 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID ZDHHC4 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID HEATR3 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID BZW2 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID H2AP GeneID BioGRID Affinity Capture-MS
MAVS BioGRID HSPBP1 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID KPTN GeneID BioGRID Affinity Capture-MS
MAVS BioGRID TDRKH GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
MAVS BioGRID CALCOCO2 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-localization; Reconstituted Complex
MAVS BioGRID OPTN GeneID BioGRID Affinity Capture-Western; Proximity Label-MS
MAVS BioGRID BAG2 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID LY86 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID SQSTM1 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID DNAH17 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID TACR3 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID SOD1 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID SLC7A1 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID RPL35A GeneID BioGRID Affinity Capture-MS
MAVS BioGRID NBR1 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID HSPA9 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID HSPA8 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID HSPA2 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID GPR17 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID GCGR GeneID BioGRID Affinity Capture-MS
MAVS BioGRID DNM2 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID AVPR2 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID CCDC50 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
MAVS BioGRID DDX39A GeneID BioGRID Affinity Capture-RNA
MAVS BioGRID UBQLN2 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID SFXN1 GeneID BioGRID Proximity Label-MS
MAVS BioGRID ACBD5 GeneID BioGRID Proximity Label-MS
MAVS BioGRID HSD3B7 GeneID BioGRID Proximity Label-MS
MAVS BioGRID MARCHF1 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID RNF115 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
MAVS BioGRID MAPRE1 GeneID BioGRID Proximity Label-MS
MAVS BioGRID PHB2 GeneID BioGRID Proximity Label-MS
MAVS BioGRID RAB35 GeneID BioGRID Proximity Label-MS
MAVS BioGRID NUP155 GeneID BioGRID Proximity Label-MS
MAVS BioGRID RAB9A GeneID BioGRID Proximity Label-MS
MAVS BioGRID AIFM1 GeneID BioGRID Proximity Label-MS
MAVS BioGRID PEX3 GeneID BioGRID Proximity Label-MS
MAVS BioGRID AKAP1 GeneID BioGRID Proximity Label-MS
MAVS BioGRID ZFPL1 GeneID BioGRID Proximity Label-MS
MAVS BioGRID RAB5C GeneID BioGRID Proximity Label-MS
MAVS BioGRID RAB5A GeneID BioGRID Proximity Label-MS
MAVS BioGRID RAB3B GeneID BioGRID Proximity Label-MS
MAVS BioGRID PXMP2 GeneID BioGRID Proximity Label-MS
MAVS BioGRID PEX14 GeneID BioGRID Proximity Label-MS
MAVS BioGRID MARCKS GeneID BioGRID Proximity Label-MS
MAVS BioGRID MAP1LC3A GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
MAVS BioGRID PSMD14 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID ABL1 GeneID BioGRID Affinity Capture-Western; Far Western
MAVS BioGRID ORF7b GeneID BioGRID Affinity Capture-MS
MAVS BioGRID M GeneID BioGRID Affinity Capture-Western
MAVS BioGRID NACC1 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID E5 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID E5a GeneID BioGRID Affinity Capture-MS
MAVS BioGRID TP53 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID DNM1L GeneID BioGRID Proximity Label-MS
MAVS BioGRID MFN2 GeneID BioGRID Affinity Capture-Western; Proximity Label-MS
MAVS BioGRID ARMCX2 GeneID BioGRID Proximity Label-MS
MAVS BioGRID PEX5 GeneID BioGRID Proximity Label-MS
MAVS BioGRID ABCD3 GeneID BioGRID Proximity Label-MS
MAVS BioGRID PTPN1 GeneID BioGRID Proximity Label-MS
MAVS BioGRID PRKAR2B GeneID BioGRID Proximity Label-MS
MAVS BioGRID PRKAR2A GeneID BioGRID Proximity Label-MS
MAVS BioGRID PDCL GeneID BioGRID Proximity Label-MS
MAVS BioGRID IFIT1 GeneID BioGRID Proximity Label-MS
MAVS BioGRID GK GeneID BioGRID Proximity Label-MS
MAVS BioGRID ADSL GeneID BioGRID Proximity Label-MS
MAVS BioGRID MIGA1 GeneID BioGRID Proximity Label-MS
MAVS BioGRID C9orf72 GeneID BioGRID Proximity Label-MS
MAVS BioGRID HSCB GeneID BioGRID Affinity Capture-MS
MAVS BioGRID SMCR8 GeneID BioGRID Proximity Label-MS
MAVS BioGRID SLC25A51 GeneID BioGRID Proximity Label-MS
MAVS BioGRID SLC25A46 GeneID BioGRID Proximity Label-MS
MAVS BioGRID TIMM29 GeneID BioGRID Proximity Label-MS
MAVS BioGRID RHOT2 GeneID BioGRID Proximity Label-MS
MAVS BioGRID USP30 GeneID BioGRID Proximity Label-MS
MAVS BioGRID CDCA3 GeneID BioGRID Proximity Label-MS
MAVS BioGRID TRABD GeneID BioGRID Proximity Label-MS
MAVS BioGRID MYO19 GeneID BioGRID Proximity Label-MS
MAVS BioGRID MFF GeneID BioGRID Proximity Label-MS
MAVS BioGRID SH3GLB2 GeneID BioGRID Proximity Label-MS
MAVS BioGRID ZC3HAV1 GeneID BioGRID Proximity Label-MS
MAVS BioGRID DIABLO GeneID BioGRID Proximity Label-MS
MAVS BioGRID CISD1 GeneID BioGRID Proximity Label-MS
MAVS BioGRID WDR41 GeneID BioGRID Proximity Label-MS
MAVS BioGRID EXD2 GeneID BioGRID Proximity Label-MS
MAVS BioGRID VPS13D GeneID BioGRID Proximity Label-MS
MAVS BioGRID RMDN3 GeneID BioGRID Proximity Label-MS
MAVS BioGRID OCIAD1 GeneID BioGRID Proximity Label-MS
MAVS BioGRID FIS1 GeneID BioGRID Proximity Label-MS
MAVS BioGRID FBXL4 GeneID BioGRID Proximity Label-MS
MAVS BioGRID SAMM50 GeneID BioGRID Proximity Label-MS
MAVS BioGRID MTCH2 GeneID BioGRID Proximity Label-MS
MAVS BioGRID MTCH1 GeneID BioGRID Proximity Label-MS
MAVS BioGRID BCL2L13 GeneID BioGRID Proximity Label-MS
MAVS BioGRID FKBP8 GeneID BioGRID Affinity Capture-Western; Proximity Label-MS; Two-hybrid
MAVS BioGRID FAF2 GeneID BioGRID Proximity Label-MS
MAVS BioGRID UBXN4 GeneID BioGRID Proximity Label-MS
MAVS BioGRID AFG3L2 GeneID BioGRID Proximity Label-MS
MAVS BioGRID YKT6 GeneID BioGRID Proximity Label-MS
MAVS BioGRID MTX2 GeneID BioGRID Proximity Label-MS
MAVS BioGRID HAX1 GeneID BioGRID Proximity Label-MS
MAVS BioGRID HTRA2 GeneID BioGRID Proximity Label-MS
MAVS BioGRID KCTD10 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID TRAF3IP3 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
MAVS BioGRID RNF34 GeneID BioGRID Affinity Capture-Western; Co-localization; Far Western; Reconstituted Complex; Two-hybrid
MAVS BioGRID STING1 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID YOD1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
MAVS BioGRID JOSD2 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID USP46 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID USP29 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID USP28 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID OTUD7B GeneID BioGRID Affinity Capture-Western
MAVS BioGRID OTUD4 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
MAVS BioGRID USP22 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID COPS6 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID USP19 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID RACK1 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID USP12 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID CYLD GeneID BioGRID Affinity Capture-Western
MAVS BioGRID USP2 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID EIF3H GeneID BioGRID Affinity Capture-Western
MAVS BioGRID USP4 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID DYNC1LI1 GeneID BioGRID Proximity Label-MS
MAVS BioGRID DYNC1LI2 GeneID BioGRID Proximity Label-MS
MAVS BioGRID TRIM21 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID COX14 GeneID BioGRID Proximity Label-MS
MAVS BioGRID TOMM22 GeneID BioGRID Proximity Label-MS
MAVS BioGRID PLGRKT GeneID BioGRID Proximity Label-MS
MAVS BioGRID PTRH2 GeneID BioGRID Proximity Label-MS
MAVS BioGRID TOMM20 GeneID BioGRID Proximity Label-MS
MAVS BioGRID SCO1 GeneID BioGRID Proximity Label-MS
MAVS BioGRID MGST3 GeneID BioGRID Proximity Label-MS
MAVS BioGRID ESR2 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID ZC3H12A GeneID BioGRID Affinity Capture-Western
MAVS BioGRID WDR82 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID TRIM25 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID TRIM40 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID PPIA GeneID BioGRID Affinity Capture-Western
MAVS BioGRID WRNIP1 GeneID BioGRID Affinity Capture-Western; Co-localization
MAVS BioGRID TRIM14 GeneID BioGRID Affinity Capture-Western; Co-fractionation; Co-localization
MAVS BioGRID TAX1BP1 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID PPP6C GeneID BioGRID Affinity Capture-Western; Co-localization
MAVS BioGRID FBXO32 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID PRKACB GeneID BioGRID Affinity Capture-Western
MAVS BioGRID PRKACA GeneID BioGRID Affinity Capture-Western
MAVS BioGRID PLAAT4 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID PRKN GeneID BioGRID Affinity Capture-Western
MAVS BioGRID RNF114 GeneID BioGRID Affinity Capture-Western; Co-fractionation; Co-localization
MAVS BioGRID RNF31 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID RAB6B GeneID BioGRID Affinity Capture-MS
MAVS BioGRID DHRS9 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID VIPR2 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID TLR1 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID PSMC3 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID CDH1 GeneID BioGRID Proximity Label-MS
MAVS BioGRID Trim31 GeneID BioGRID Biochemical Activity
MAVS BioGRID DDX3X GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
MAVS BioGRID CSNK1E GeneID BioGRID Affinity Capture-Western
MAVS BioGRID IRF3 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
MAVS BioGRID IKBKG GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
MAVS BioGRID CISD3 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID COQ9 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID TRAF1 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID RNF166 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID HERC2 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID NUP35 GeneID BioGRID Proximity Label-MS
MAVS BioGRID NFKBIA GeneID BioGRID Affinity Capture-Western
MAVS BioGRID IKBKB GeneID BioGRID Biochemical Activity
MAVS BioGRID CHRNA9 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID IFIT3 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID MIB2 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID KCNIP3 GeneID BioGRID Two-hybrid
MAVS BioGRID UBXN1 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID SMURF2 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
MAVS BioGRID POLY GeneID BioGRID Proximity Label-MS
MAVS BioGRID AMFR GeneID BioGRID Affinity Capture-Western
MAVS BioGRID MFN1 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID MUL1 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID TOMM70 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID FLOT2 GeneID BioGRID Co-fractionation
MAVS BioGRID NDFIP1 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID TICAM1 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID MAP3K7 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID SRC GeneID BioGRID Affinity Capture-Western
MAVS BioGRID IRF7 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID TSPAN6 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID ECSIT GeneID BioGRID Affinity Capture-Western
MAVS BioGRID PSMA7 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID WDR5 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID HECTD3 GeneID BioGRID Affinity Capture-MS
MAVS BioGRID PDS5A GeneID BioGRID Affinity Capture-MS
MAVS BioGRID KRR1 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID UBE4A GeneID BioGRID Affinity Capture-MS; Reconstituted Complex
MAVS BioGRID FADD GeneID BioGRID Affinity Capture-Western
MAVS BioGRID RIPK2 GeneID BioGRID Affinity Capture-MS; Reconstituted Complex
MAVS BioGRID STAT1 GeneID BioGRID Affinity Capture-MS; Reconstituted Complex
MAVS BioGRID OAS3 GeneID BioGRID Affinity Capture-MS; Reconstituted Complex
MAVS BioGRID IRF5 GeneID BioGRID Affinity Capture-MS; Reconstituted Complex
MAVS BioGRID OTUB2 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID OTUB1 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID BIRC3 GeneID BioGRID Affinity Capture-Western
MAVS BioGRID BIRC2 GeneID BioGRID Affinity Capture-Western
MAVS None RIGI GeneID HPRD
MAVS None TICAM1 GeneID HPRD
MAVS None IRF7 GeneID HPRD
MAVS None TBK1 GeneID HPRD
MAVS None IRF3 GeneID HPRD
MAVS None MAP3K7 GeneID HPRD
MAVS None TRAF6 GeneID HPRD
StringDB
A B experiments database textmining combined score hadb nhadb
MAVS TOPORS 0 0 0 207 1 1
MAVS XIAP 0 0 193 193 1 2
MAVS PML 0 0 218 259 1 2
MAVS TLR4 0 0 566 575 1 2
MAVS USP46 270 0 0 322 1 1
MAVS GAPDH 0 0 458 468 1 2
MAVS RNF216 0 900 107 912 1 1
MAVS ATG14 0 0 156 155 1 2
MAVS CLEC4C 0 0 159 158 1 1
MAVS IFNLR1 0 0 459 459 1 1
MAVS SLC10A1 0 0 92 167 1 1
MAVS FKBP8 350 0 123 405 1 1
MAVS PANX1 0 0 157 156 1 1
MAVS GABARAPL2 0 0 181 181 1 2
MAVS MARCH8 0 0 268 268 1 1
MAVS CLDN1 0 0 180 236 1 1
MAVS CD83 0 0 150 173 1 1
MAVS SCN5A 0 0 327 327 1 1
MAVS ATF6 0 0 142 161 1 2
MAVS IKBKB 674 800 619 973 1 2
MAVS OAS2 0 0 393 429 1 1
MAVS NLRC4 0 0 507 507 1 2
MAVS NARS 0 0 63 161 1 1
MAVS MAP2K7 0 0 425 425 1 1
MAVS ABL1 297 0 71 329 1 1
MAVS IFIT3 270 0 474 608 1 1
MAVS TRIM25 486 600 917 985 1 1
MAVS B9D1 0 0 0 181 1 1
MAVS MAP3K15 0 0 56 151 1 1
MAVS TMEM203 0 0 161 179 1 1
MAVS CD4 0 0 454 454 1 2
MAVS INPP5D 0 0 358 358 1 1
MAVS PRKCG 0 0 0 205 1 1
MAVS STAT4 0 0 141 435 1 1
MAVS SUMO1 0 0 171 171 1 1
MAVS TAB3 0 0 265 265 1 1
MAVS FAS 0 0 136 158 1 2
MAVS JADE2 0 0 120 184 1 1
MAVS CLEC7A 0 0 252 252 1 1
MAVS TLR10 0 0 236 306 1 1
MAVS ENSG00000250349 0 0 167 167 1 1
MAVS CARD14 0 0 127 177 1 1
MAVS CARD8 0 0 152 184 1 1
MAVS UBR4 0 0 209 230 1 1
MAVS CSF2 0 0 322 321 1 1
MAVS PARP4 0 0 44 297 1 1
MAVS NFKB1 0 650 124 694 1 2
MAVS LY96 0 0 261 261 1 1
MAVS COX5B 0 0 819 823 1 1
MAVS UBE3A 0 0 150 198 1 1
MAVS WRNIP1 270 0 47 274 1 1
MAVS AKT1 0 0 267 278 1 2
MAVS RELA 0 650 370 775 1 2
MAVS GBP2 0 0 181 193 1 1
MAVS TRAF3IP1 0 0 145 181 1 1
MAVS DDX10 0 0 0 248 1 1
MAVS BCL2L1 0 0 241 240 1 2
MAVS GRIA2 0 0 149 296 1 1
MAVS PDE4C 0 0 0 181 1 1
MAVS NLRP7 0 0 292 385 1 1
MAVS ANXA5 0 0 317 317 1 2
MAVS FAM196A 0 0 95 327 1 1
MAVS IRF3 878 600 971 998 1 2
MAVS UBA7 0 0 232 317 1 1
MAVS RNASEH2B 0 0 284 289 1 1
MAVS SLC25A6 0 0 253 278 1 1
MAVS FBXO32 270 0 0 270 1 2
MAVS UBE2E2 0 0 166 165 1 1
MAVS KRR1 270 0 0 270 1 1
MAVS GSDMA 0 0 157 156 1 1
MAVS TLR9 0 0 651 683 1 2
MAVS PYCARD 0 0 460 539 1 2
MAVS MAP3K1 0 600 137 640 1 1
MAVS PRKRA 0 0 181 181 1 1
MAVS TRIM10 0 0 0 159 1 1
MAVS PLK1 423 0 870 923 1 2
MAVS HSF1 0 0 0 189 1 2
MAVS CD1D 0 0 125 154 1 1
MAVS ZNHIT2 0 0 0 188 1 1
MAVS LONP1 0 0 141 173 1 1
MAVS SDHB 0 0 183 183 1 1
MAVS MALT1 0 0 545 545 1 1
MAVS UBE2D3 0 0 184 183 1 1
MAVS PRKACA 270 0 0 270 1 1
MAVS HAVCR1 0 0 0 302 1 1
MAVS CXCL10 0 0 518 537 1 2
MAVS USP25 0 0 236 314 1 1
MAVS CYLD 486 0 464 712 1 1
MAVS PLGRKT 226 0 0 225 1 1
MAVS PHF20 0 0 166 165 1 1
MAVS AXL 0 0 123 186 1 2
MAVS CREBBP 0 0 155 177 1 1
MAVS MOV10 0 0 180 215 1 1
MAVS TRIM9 0 0 162 161 1 1
MAVS GP2 0 0 156 155 1 1
MAVS TAAR2 0 0 0 175 1 1
MAVS DDX56 0 0 459 459 1 1
MAVS DHX9 0 0 955 957 1 1
MAVS USP3 0 0 325 325 1 1
MAVS IFNG 0 0 140 491 1 2
MAVS BIRC2 270 0 459 588 1 1
MAVS PINK1 0 0 323 337 1 2
MAVS DHX35 0 0 0 243 1 1
MAVS IFNGR2 0 0 195 201 1 1
MAVS WWP1 0 0 47 169 1 1
MAVS GSDMD 0 0 310 325 1 2
MAVS PHGDH 0 0 163 163 1 1
MAVS C9orf89 0 0 242 241 1 1
MAVS SSR2 0 0 501 501 1 1
MAVS CCL5 0 0 457 457 1 2
MAVS USP12 270 0 0 322 1 2
MAVS NLRC3 0 0 459 462 1 1
MAVS PIK3C3 0 0 220 220 1 2
MAVS STAT6 270 0 444 612 1 1
MAVS YOD1 270 0 90 307 1 1
MAVS IL6 0 0 517 527 1 2
MAVS ZBTB24 0 0 47 243 1 1
MAVS EIF2AK3 0 0 181 191 1 2
MAVS WWP2 0 0 74 203 1 1
MAVS TXNDC9 0 0 235 235 1 1
MAVS STAT1 157 0 684 752 1 2
MAVS SOCS5 0 0 124 215 1 1
MAVS ATG3 0 0 170 169 1 2
MAVS DNAJB1 0 0 108 163 1 2
MAVS OCLN 0 0 170 221 1 1
MAVS GZMB 0 0 218 227 1 1
MAVS TNFRSF1A 0 0 583 592 1 1
MAVS TLR3 0 0 762 843 1 2
MAVS TRIM28 0 0 170 182 1 2
MAVS GMPS 0 0 142 173 1 1
MAVS PARP9 0 0 82 317 1 1
MAVS RSAD2 0 0 761 778 1 1
MAVS PEX19 0 0 342 376 1 1
MAVS SMOX 0 0 53 224 1 1
MAVS C1QBP 312 0 963 974 1 1
MAVS TRAF4 0 0 320 345 1 1
MAVS CDC42 0 0 60 156 1 2
MAVS SMURF2 270 0 193 447 1 1
MAVS SEC61A1 0 0 431 431 1 1
MAVS SAMD9L 0 0 134 175 1 1
MAVS IRF8 0 0 290 295 1 1
MAVS SRC 270 0 307 480 1 2
MAVS C4orf22 0 0 93 171 1 1
MAVS ADA 0 0 294 309 1 1
MAVS TRIM59 0 0 150 294 1 1
MAVS VDAC3 0 0 183 194 1 1
MAVS RAD51 0 0 166 165 1 2
MAVS MTOR 0 0 181 181 1 2
MAVS APOBEC3G 0 0 261 261 1 1
MAVS APOE 0 0 103 159 1 2
MAVS BBOX1 0 0 391 390 1 1
MAVS NLRP1 0 0 457 457 1 1
MAVS USP2 270 0 45 273 1 1
MAVS ADAR 0 0 467 503 1 1
MAVS DDX21 0 0 455 455 1 1
MAVS MCU 0 0 351 351 1 2
MAVS KPNA1 0 0 229 228 1 1
MAVS PEX13 0 0 260 373 1 1
MAVS CTNNB1 0 0 181 181 1 2
MAVS CLRN3 0 0 71 383 1 1
MAVS MAP1LC3A 270 0 71 292 1 2
MAVS AKR1C3 0 0 242 241 1 1
MAVS USP7 0 0 174 180 1 1
MAVS TRIM13 0 0 210 342 1 1
MAVS DUSP11 0 0 112 266 1 1
MAVS RIPK3 0 0 529 547 1 2
MAVS IFIT1 118 0 653 683 1 1
MAVS RNF145 0 0 49 259 1 1
MAVS MFN2 350 800 976 996 1 2
MAVS HAUS8 0 0 181 181 1 1
MAVS IFNA4 0 0 432 433 1 1
MAVS RNF24 0 0 60 302 1 1
MAVS VDAC1 0 0 526 547 1 2
MAVS MYOM2 0 0 358 358 1 1
MAVS STAT5B 0 0 91 177 1 1
MAVS PLA2G4A 0 0 454 454 1 1
MAVS RAB7B 0 0 178 177 1 1
MAVS TRIM4 0 0 459 467 1 1
MAVS IKBKE 871 600 801 995 1 1
MAVS ABCD3 117 0 287 393 1 1
MAVS HERC5 0 0 295 322 1 1
MAVS DDX18 0 0 0 252 1 1
MAVS TRIM29 0 0 254 260 1 1
MAVS DDX20 0 0 75 167 1 1
MAVS COQ9 195 0 0 195 1 1
MAVS BNIP3L 0 0 167 173 1 2
MAVS PNPT1 0 0 141 164 1 1
MAVS OAS1 0 0 504 504 1 1
MAVS DHX32 0 0 101 201 1 1
MAVS TRIM27 0 0 242 259 1 1
MAVS NEDD4 0 0 167 269 1 2
MAVS TRAF5 835 0 885 981 1 1
MAVS JAK1 0 0 468 496 1 2
MAVS EIF2S1 0 0 374 374 1 2
MAVS PRKCB 0 0 108 260 1 2
MAVS UQCRC2 0 0 271 271 1 1
MAVS PIAS4 0 0 122 184 1 1
MAVS TOMM20 117 0 370 441 1 2
MAVS RAC2 0 0 57 167 1 1
MAVS IL1B 0 0 557 572 1 2
MAVS DDX39B 0 0 140 158 1 1
MAVS TBPL2 0 0 123 233 1 1
MAVS MARCH5 350 0 555 698 1 1
MAVS NDUFAF1 0 0 0 165 1 1
MAVS NDFIP1 270 0 442 575 1 1
MAVS ADAP2 0 0 166 182 1 1
MAVS CXCL8 0 0 395 406 1 2
MAVS PPWD1 0 0 74 172 1 1
MAVS TBK1 880 600 989 999 1 2
MAVS GOLM1 0 0 186 192 1 1
MAVS TICAM2 0 0 180 236 1 1
MAVS DHRS9 285 0 0 284 1 1
MAVS RNF11 0 0 217 217 1 1
MAVS SUMO2 0 0 155 154 1 1
MAVS TRIM14 486 0 923 959 1 1
MAVS FOXP3 0 0 158 157 1 2
MAVS DOCK1 0 0 0 216 1 1
MAVS PEX11A 0 0 158 157 1 1
MAVS XRCC6 0 0 205 205 1 1
MAVS TRIM23 0 0 323 368 1 1
MAVS ERN1 0 0 224 252 1 2
MAVS TRIM42 0 0 150 200 1 1
MAVS LYPD6 0 0 58 152 1 1
MAVS CAT 0 0 150 185 1 2
MAVS UBB 800 0 92 810 1 1
MAVS AGO2 0 0 213 214 1 2
MAVS EIF2AK4 0 0 150 171 1 2
MAVS IFNA2 0 0 392 419 1 1
MAVS VDAC2 0 0 454 454 1 1
MAVS CANX 0 0 207 207 1 2
MAVS CD300C 0 0 263 263 1 1
MAVS TRIM8 0 0 135 201 1 1
MAVS STAT3 0 0 244 320 1 2
MAVS USP13 0 0 378 378 1 1
MAVS FAF2 117 0 86 176 1 1
MAVS JAK2 0 0 182 194 1 2
MAVS NLRC5 0 900 641 963 1 1
MAVS DOCK5 0 0 45 251 1 1
MAVS DDX46 0 0 195 196 1 1
MAVS RNASEL 0 0 669 709 1 1
MAVS HPRT1 0 0 139 164 1 1
MAVS CD46 0 0 174 173 1 2
MAVS HSCB 270 0 0 270 1 1
MAVS SKIV2L 0 0 253 252 1 1
MAVS G3BP2 0 0 154 186 1 1
MAVS RHEB 0 0 58 173 1 2
MAVS EXOC2 0 0 415 419 1 1
MAVS APAF1 0 0 261 261 1 2
MAVS IFI44 0 0 246 245 1 1
MAVS HDAC6 0 0 163 163 1 2
MAVS SRSF1 0 0 444 444 1 1
MAVS PSMA7 270 0 520 748 1 1
MAVS CTLA4 0 0 218 218 1 2
MAVS KCTD10 270 0 0 270 1 1
MAVS BAG6 211 0 0 211 1 1
MAVS SERAC1 0 0 57 200 1 1
MAVS UBE4A 157 0 58 231 1 1
MAVS CARD18 0 0 235 264 1 1
MAVS CAPRIN1 0 0 136 190 1 1
MAVS EIF3H 270 0 0 270 1 1
MAVS GNB2L1 270 0 95 311 1 1
MAVS EXO1 0 0 139 161 1 1
MAVS GEMIN5 0 0 89 157 1 1
MAVS IRAK1 0 800 504 900 1 1
MAVS TRIM65 0 0 473 481 1 1
MAVS FLT3LG 0 0 122 255 1 1
MAVS PEF1 0 0 106 157 1 1
MAVS HK2 0 0 384 384 1 2
MAVS DOK3 0 0 88 193 1 1
MAVS CD274 0 0 217 217 1 2
MAVS CAMP 0 0 229 228 1 2
MAVS TRAF1 270 0 334 517 1 1
MAVS LSM14A 0 0 262 314 1 1
MAVS CARD9 0 0 403 403 1 1
MAVS RMDN3 117 0 141 209 1 1
MAVS TGIF2LX 0 0 134 188 1 1
MAVS AIMP1 0 0 81 220 1 1
MAVS TRIM15 0 0 181 515 1 1
MAVS TRIM40 270 0 94 321 1 1
MAVS IFIT2 0 0 556 556 1 1
MAVS MAP3K7 270 800 242 881 1 2
MAVS CCDC58 0 0 125 188 1 1
MAVS LPP 0 0 0 162 1 1
MAVS NLRP4 0 0 391 390 1 1
MAVS PTPRE 0 0 45 211 1 1
MAVS CD19 0 0 180 179 1 1
MAVS SPECC1 0 0 294 294 1 1
MAVS LHFPL1 0 0 120 254 1 1
MAVS IRAK2 0 0 325 348 1 1
MAVS PSMA8 0 0 0 245 1 1
MAVS CRADD 0 0 166 165 1 1
MAVS LCP2 0 0 0 160 1 1
MAVS ZBP1 0 0 517 535 1 1
MAVS PABPC1 0 0 177 177 1 1
MAVS UXT 0 0 171 171 1 1
MAVS IRF9 0 0 602 610 1 1
MAVS TP53 0 0 268 268 1 2
MAVS DDX60 0 0 617 617 1 1
MAVS DDX23 0 0 62 152 1 1
MAVS MGA 0 0 483 483 1 1
MAVS CBL 0 0 139 184 1 1
MAVS HSPA9 130 0 159 237 1 1
MAVS TAAR5 0 0 57 226 1 1
MAVS C6orf203 0 0 108 202 1 1
MAVS TRIM24 0 0 124 181 1 1
MAVS LAMP1 0 0 189 206 1 2
MAVS LRRC25 0 0 184 183 1 1
MAVS ACBD5 117 0 66 170 1 2
MAVS RNASEH2A 0 0 298 302 1 1
MAVS SARM1 0 0 265 270 1 1
MAVS ESX1 0 0 160 159 1 1
MAVS EIF4E 0 0 162 161 1 2
MAVS FADD 270 600 942 983 1 2
MAVS NLRP2 0 0 68 191 1 1
MAVS HTT 0 0 70 213 1 2
MAVS MYD88 0 0 688 753 1 2
MAVS PPP1CC 0 0 268 346 1 1
MAVS TNFRSF4 0 0 127 164 1 1
MAVS CFLAR 0 0 289 377 1 2
MAVS RNF41 0 0 289 318 1 1
MAVS NLRP10 0 0 212 212 1 1
MAVS SOCS1 0 0 341 346 1 1
MAVS MARCH7 0 0 170 197 1 1
MAVS GDAP1 0 0 108 201 1 1
MAVS TLR1 129 0 391 450 1 1
MAVS PGAM5 270 0 448 580 1 1
MAVS UVRAG 0 0 166 169 1 2
MAVS IRF7 270 600 815 962 1 1
MAVS G3BP1 0 0 372 411 1 1
MAVS FURIN 0 0 134 162 1 1
MAVS USP38 0 0 96 294 1 1
MAVS RBCK1 0 0 300 333 1 1
MAVS OASL 0 0 466 499 1 1
MAVS ITPA 0 0 218 218 1 1
MAVS USP19 270 0 165 364 1 1
MAVS NLRP12 0 0 369 369 1 1
MAVS IFITM2 0 0 294 338 1 1
MAVS RAB1B 0 0 260 260 1 2
MAVS GBP5 0 0 264 264 1 1
MAVS CD80 0 0 233 232 1 2
MAVS IFNL1 0 0 503 537 1 1
MAVS IFI35 0 0 244 349 1 1
MAVS PPIF 0 0 147 203 1 1
MAVS MAP3K8 0 0 113 160 1 1
MAVS CARD10 0 0 212 229 1 1
MAVS CH25H 0 0 181 181 1 1
MAVS OPA1 117 0 75 171 1 2
MAVS DHX58 0 0 982 985 1 1
MAVS TCF3 0 0 134 193 1 1
MAVS MFF 117 0 259 333 1 1
MAVS C10orf120 0 0 150 208 1 1
MAVS IFNL2 0 0 467 503 1 1
MAVS NOL3 0 0 453 453 1 1
MAVS TXNIP 0 0 193 210 1 2
MAVS SMC5 0 0 100 239 1 1
MAVS MTHFD2L 0 0 0 206 1 1
MAVS IFI16 0 0 662 662 1 1
MAVS OAS3 157 0 344 458 1 1
MAVS PRSS57 0 0 334 334 1 1
MAVS UBE2J1 0 0 94 156 1 1
MAVS RELB 0 0 258 258 1 2
MAVS RAB7A 0 0 165 165 1 2
MAVS BCAP31 0 0 120 163 1 1
MAVS CLEC4A 0 0 125 159 1 1
MAVS CASP10 0 600 261 733 1 1
MAVS TNFAIP3 0 0 211 211 1 2
MAVS NFKB2 0 650 218 726 1 1
MAVS UBD 0 0 194 194 1 1
MAVS CISD3 208 0 0 208 1 1
MAVS RNF166 270 0 120 430 1 1
MAVS IFNAR1 0 0 710 739 1 1
MAVS AZIN1 0 0 107 202 1 1
MAVS TAX1BP1 270 0 391 584 1 2
MAVS IL5 0 0 153 152 1 1
MAVS USP14 0 0 195 195 1 2
MAVS SLC15A4 0 0 184 185 1 1
MAVS TRAF2 870 800 805 995 1 2
MAVS DDX3X 486 0 952 974 1 1
MAVS TAB1 0 800 341 867 1 1
MAVS ITCH 486 600 633 935 1 1
MAVS MX1 0 0 601 625 1 1
MAVS MEFV 0 0 557 565 1 1
MAVS PPP1R15A 0 0 166 165 1 2
MAVS DHX33 0 800 836 967 1 1
MAVS USP15 0 0 329 329 1 1
MAVS CMC1 0 0 0 161 1 1
MAVS RNF135 0 600 751 900 1 1
MAVS CD209 0 0 315 315 1 1
MAVS HERC6 0 0 73 196 1 1
MAVS KNCN 0 0 120 153 1 1
MAVS SERPINA5 0 0 125 151 1 1
MAVS ERV3-1 0 0 166 165 1 1
MAVS TRAF3IP3 270 0 103 317 1 1
MAVS NAIP 0 0 259 258 1 1
MAVS IFI27 0 0 324 323 1 1
MAVS FIS1 117 0 322 375 1 2
MAVS IFITM3 0 0 391 429 1 1
MAVS KRT37 0 0 161 161 1 1
MAVS IRGM 0 0 279 279 1 2
MAVS IL15 0 0 218 235 1 1
MAVS RNF125 270 0 609 734 1 1
MAVS ITGAE 0 0 203 203 1 1
MAVS MYC 0 0 547 553 1 2
MAVS IL1R1 0 0 378 378 1 1
MAVS RARRES3 835 0 81 841 1 1
MAVS TRAPPC9 0 0 57 193 1 1
MAVS PARK2 270 0 433 568 1 1
MAVS PPIP5K1 0 0 415 414 1 1
MAVS IFNA1 0 0 737 737 1 1
MAVS IL18 0 0 518 526 1 2
MAVS HERC2 270 0 0 270 1 1
MAVS AZI2 0 0 281 281 1 1
MAVS TIRAP 0 0 460 459 1 1
MAVS SDHC 0 0 247 275 1 1
MAVS LARS 0 0 53 298 1 1
MAVS TAB2 0 800 342 862 1 2
MAVS NBR1 0 0 260 260 1 2
MAVS IFITM1 0 0 322 364 1 1
MAVS HPSE 0 0 108 192 1 1
MAVS UBE2D1 0 0 230 229 1 1
MAVS TNF 0 0 519 543 1 2
MAVS TANK 0 600 951 980 1 2
MAVS PCBP2 486 600 772 950 1 1
MAVS STAT2 0 0 611 652 1 1
MAVS RNASEH2C 0 0 321 333 1 1
MAVS ARSK 0 0 90 230 1 1
MAVS CXCR3 0 0 180 179 1 1
MAVS IRF2 0 0 246 250 1 1
MAVS HSPA4 0 0 180 180 1 1
MAVS XBP1 0 0 150 173 1 2
MAVS USP22 270 0 432 567 1 1
MAVS TRIM5 0 0 414 423 1 1
MAVS DICER1 0 0 292 292 1 1
MAVS RIOK3 0 0 183 188 1 1
MAVS USP29 270 0 0 270 1 1
MAVS IRF1 0 0 602 637 1 2
MAVS ENDOU 0 0 181 310 1 1
MAVS CALCOCO2 634 0 391 767 1 2
MAVS LRPPRC 0 0 174 174 1 2
MAVS ATG5 270 800 600 950 1 2
MAVS RNF114 270 0 125 403 1 1
MAVS ISG20 0 0 392 402 1 1
MAVS C5orf47 0 0 125 156 1 1
MAVS DDX1 0 0 567 567 1 1
MAVS NLRP14 0 0 118 169 1 1
MAVS PTPRA 0 0 0 210 1 1
MAVS TIA1 0 0 262 278 1 1
MAVS TLR8 0 0 560 565 1 1
MAVS SH2D3A 0 0 576 576 1 1
MAVS CXCL9 0 0 249 248 1 1
MAVS RNF144B 0 0 0 188 1 1
MAVS MAP3K5 0 0 117 157 1 1
MAVS OPTN 131 0 323 407 1 2
MAVS PYHIN1 0 0 241 240 1 1
MAVS CASP9 0 0 243 272 1 2
MAVS EYA4 0 0 700 700 1 1
MAVS TRAF6 978 800 988 999 1 2
MAVS SEC14L1 0 0 218 218 1 1
MAVS GNRH2 0 0 0 206 1 1
MAVS ITGAM 0 0 265 265 1 1
MAVS CYCS 0 0 296 296 1 2
MAVS UBE2D2 0 0 173 173 1 1
MAVS LYN 0 0 87 213 1 1
MAVS LCA5 0 0 0 189 1 1
MAVS DFNA5 0 0 113 248 1 1
MAVS TLR7 0 0 703 748 1 2
MAVS DHX36 0 0 524 561 1 1
MAVS RAC3 0 0 0 152 1 2
MAVS AFG3L2 117 0 61 158 1 1
MAVS PPP1CA 0 0 400 415 1 1
MAVS NWD2 0 0 257 256 1 1
MAVS IFNB1 0 0 857 871 1 1
MAVS NCL 0 0 149 295 1 2
MAVS IRF5 157 0 519 606 1 1
MAVS HMGB1 0 0 215 215 1 2
MAVS RAC1 0 0 55 151 1 2
MAVS CXCL11 0 0 218 218 1 1
MAVS SIKE1 0 650 325 753 1 1
MAVS CTSB 0 0 181 181 1 2
MAVS IL17A 0 0 244 243 1 2
MAVS SLC25A17 0 0 211 224 1 1
MAVS TMEM2 0 0 107 309 1 1
MAVS PAN2 0 0 432 432 1 1
MAVS NACC1 0 0 454 454 1 1
MAVS ELF4 0 0 763 768 1 1
MAVS PELI1 0 0 217 300 1 1
MAVS HECTD3 157 0 0 192 1 1
MAVS IL10RB 0 0 310 315 1 1
MAVS ERVW-1 0 0 228 227 1 1
MAVS TIAL1 0 0 209 278 1 1
MAVS PCBP1 0 0 162 161 1 1
MAVS PLEKHM3 0 0 181 181 1 1
MAVS IKBKG 806 800 812 992 1 1
MAVS CCR7 0 0 141 163 1 1
MAVS PEX5 117 0 134 202 1 1
MAVS MARCH4 0 0 122 166 1 1
MAVS CXCR5 0 0 93 257 1 1
MAVS MAPK8 0 0 203 203 1 2
MAVS SEC61B 0 0 398 398 1 1
MAVS OTUD1 0 0 143 176 1 1
MAVS GLRX3 0 0 0 216 1 1
MAVS KCTD9 0 0 61 270 1 1
MAVS PRKCA 0 0 134 370 1 1
MAVS ULK1 0 0 205 205 1 2
MAVS LATS1 0 0 95 183 1 1
MAVS UBC 800 0 107 813 1 2
MAVS ISG15 0 0 681 763 1 2
MAVS TUFM 0 0 626 634 1 2
MAVS BATF3 0 0 167 187 1 1
MAVS MAP1LC3B 0 0 193 204 1 2
MAVS OTUB1 270 0 251 429 1 1
MAVS KPTN 195 0 0 195 1 1
MAVS DNASE2 0 0 142 160 1 1
MAVS NFKBIB 0 650 125 700 1 1
MAVS IFIH1 870 800 989 999 1 1
MAVS DIABLO 118 0 210 273 1 2
MAVS SLC15A3 0 0 150 194 1 1
MAVS TTLL12 0 0 410 410 1 1
MAVS P2RX7 0 0 164 170 1 2
MAVS USP18 0 0 503 506 1 1
MAVS CPEB1 0 0 216 216 1 1
MAVS USP30 117 0 155 221 1 1
MAVS MX2 0 0 391 429 1 1
MAVS PRF1 0 0 210 210 1 1
MAVS CISH 0 0 297 297 1 1
MAVS ENSG00000255819 0 0 175 175 1 1
MAVS BPNT1 0 0 46 182 1 1
MAVS RNF128 0 0 122 176 1 1
MAVS IL10 0 0 391 390 1 2
MAVS CCL20 0 0 123 274 1 1
MAVS MIEF2 0 0 167 167 1 1
MAVS PSMB10 0 0 52 160 1 1
MAVS NICN1 0 0 82 222 1 1
MAVS IRAK4 0 800 421 882 1 1
MAVS CXCL2 0 0 181 232 1 1
MAVS RNF31 270 0 369 519 1 1
MAVS DHX8 0 0 0 557 1 1
MAVS CRYGC 0 0 261 261 1 1
MAVS TRAT1 0 0 557 557 1 1
MAVS OTUD5 0 900 463 946 1 1
MAVS GBP1 0 0 262 273 1 1
MAVS CCL4 0 0 233 232 1 1
MAVS ATG7 0 0 287 286 1 2
MAVS IL1A 0 0 233 232 1 1
MAVS CMPK2 0 0 143 166 1 1
MAVS TRADD 0 800 985 997 1 1
MAVS ACTG1 0 0 122 188 1 1
MAVS PDS5A 157 0 0 156 1 1
MAVS CUL5 0 0 134 164 1 1
MAVS KCNIP3 302 0 0 302 1 1
MAVS LITAF 0 0 65 227 1 1
MAVS TRIM26 0 0 193 211 1 1
MAVS CCL3 0 0 247 246 1 1
MAVS ICT1 0 0 56 154 1 1
MAVS AIM2 0 0 632 637 1 2
MAVS DDX58 981 800 990 999 1 1
MAVS DDX41 0 0 651 668 1 1
MAVS BCL2L13 117 0 141 209 1 2
MAVS ADARB1 0 0 143 213 1 1
MAVS RNF26 0 0 246 264 1 1
MAVS CTSD 0 0 700 700 1 2
MAVS COA3 270 0 0 270 1 1
MAVS TRIM21 270 0 417 576 1 1
MAVS UBXN1 270 0 937 954 1 1
MAVS TSPAN6 270 0 816 859 1 1
MAVS OTUB2 270 0 222 407 1 1
MAVS DDX55 0 0 0 254 1 1
MAVS DNASE1L3 0 0 180 179 1 1
MAVS MB21D1 0 0 759 782 1 1
MAVS TOMM70A 270 0 981 986 1 1
MAVS TRIM32 0 0 289 300 1 1
MAVS CLEC4E 0 0 157 156 1 1
MAVS CSF3R 0 0 0 207 1 1
MAVS EP300 0 0 193 194 1 2
MAVS PSMC3 236 0 0 236 1 1
MAVS RCHY1 0 0 60 226 1 1
MAVS MAPK14 0 0 134 166 1 2
MAVS MAPK10 0 0 226 226 1 2
MAVS IL4 0 0 261 261 1 1
MAVS SCARB1 0 0 167 200 1 1
MAVS RNF157 0 0 56 200 1 1
MAVS ROBO3 0 0 432 530 1 1
MAVS IFNA6 0 0 497 498 1 1
MAVS BIRC3 270 0 171 408 1 1
MAVS ZC3H12A 270 0 684 765 1 1
MAVS UBOX5 0 0 108 393 1 1
MAVS IFI44L 0 0 252 252 1 1
MAVS RHOT2 117 0 150 270 1 1
MAVS SYK 0 0 233 261 1 2
MAVS NFKBIA 270 650 468 858 1 2
MAVS CCDC27 0 0 96 155 1 1
MAVS EIF4A1 0 0 152 151 1 1
MAVS CYTIP 0 0 54 151 1 1
MAVS DNM1L 117 0 341 393 1 2
MAVS CASP5 0 0 215 298 1 1
MAVS OTULIN 0 0 182 199 1 1
MAVS TRIM62 0 0 159 172 1 1
MAVS TRAF7 0 0 325 350 1 1
MAVS PANK2 0 0 0 187 1 1
MAVS CD276 0 0 159 165 1 1
MAVS IDO1 0 0 150 168 1 1
MAVS CARD17 0 0 160 249 1 1
MAVS IFI6 0 0 290 290 1 1
MAVS ALB 0 0 261 322 1 2
MAVS CASP8 0 600 835 941 1 2
MAVS LRRFIP1 0 0 424 428 1 1
MAVS KIAA0226 0 0 172 171 1 1
MAVS CCL2 0 0 323 323 1 2
MAVS NLRP6 0 0 450 487 1 1
MAVS IFNA21 0 0 391 392 1 1
MAVS FPR1 0 0 146 169 1 1
MAVS IRF4 0 0 180 179 1 1
MAVS BST2 0 0 487 499 1 1
MAVS ACSL4 0 0 127 164 1 1
MAVS TRAFD1 0 0 676 676 1 1
MAVS NEK7 63 0 181 209 1 1
MAVS PLP2 0 0 368 373 1 1
MAVS DYRK4 0 0 0 167 1 1
MAVS USP28 270 0 0 320 1 1
MAVS CUL1 0 0 134 160 1 1
MAVS TRIM41 0 0 141 240 1 1
MAVS DAK 0 650 260 729 1 1
MAVS CXCL1 0 0 217 265 1 2
MAVS IL33 0 0 160 159 1 2
MAVS CPSF4 0 0 284 302 1 1
MAVS UBE2V1 0 0 282 282 1 1
MAVS HPGDS 0 0 194 194 1 1
MAVS HSP90AA1 0 0 361 361 1 2
MAVS NLRP3 486 800 988 998 1 2
MAVS REL 0 0 267 267 1 2
MAVS CARD16 0 0 108 203 1 1
MAVS FOSL1 0 0 47 256 1 1
MAVS COX4I1 0 0 186 203 1 1
MAVS DHX29 0 0 261 297 1 1
MAVS DAXX 0 0 152 162 1 1
MAVS SIDT2 0 0 76 174 1 1
MAVS DYRK2 0 0 81 283 1 1
MAVS PGLYRP1 0 0 123 177 1 1
MAVS ZPLD1 0 0 123 177 1 1
MAVS ATF2 0 0 171 191 1 1
MAVS MUL1 270 0 483 607 1 2
MAVS HTRA2 93 0 101 164 1 1
MAVS IFIT5 0 0 334 339 1 1
MAVS CLEC4M 0 0 180 179 1 1
MAVS SMURF1 270 0 469 637 1 1
MAVS WDR82 270 0 0 270 1 1
MAVS CASP3 0 0 324 350 1 2
MAVS SP100 0 0 156 169 1 1
MAVS DHX57 0 0 107 153 1 1
MAVS CD40 0 0 299 299 1 2
MAVS STUB1 0 0 139 157 1 2
MAVS NLRX1 486 800 989 998 1 2
MAVS PPM1B 0 0 216 313 1 1
MAVS EPRS 0 0 73 474 1 1
MAVS ATG12 270 800 965 995 1 2
MAVS IL13 0 0 183 183 1 2
MAVS ACTB 0 0 469 486 1 2
MAVS SQSTM1 270 0 320 482 1 2
MAVS FCGR2B 0 0 143 161 1 1
MAVS KCNF1 0 0 260 260 1 1
MAVS TRIM56 0 0 451 484 1 1
MAVS TRIM22 0 0 328 338 1 1
MAVS RNF5 270 0 711 785 1 1
MAVS CYBB 0 0 202 202 1 2
MAVS CSNK1E 270 0 0 270 1 1
MAVS ASZ1 0 0 212 212 1 1
MAVS CXCL5 0 0 62 156 1 1
MAVS TIPARP 0 0 103 197 1 1
MAVS STK38 0 0 140 199 1 1
MAVS IFNA5 0 0 217 252 1 1
MAVS PPIA 270 0 216 451 1 1
MAVS MAPK3 0 0 133 155 1 2
MAVS IFNAR2 0 0 506 506 1 1
MAVS SLC4A5 0 0 0 211 1 1
MAVS EIF4G1 0 0 262 297 1 2
MAVS SOCS2 0 0 164 175 1 1
MAVS PARP1 0 0 108 205 1 2
MAVS CASP4 0 0 67 166 1 2
MAVS PPP6C 270 0 123 334 1 1
MAVS SFN 0 0 397 396 1 2
MAVS HSPA8 131 0 73 159 1 2
MAVS RPS27A 270 0 53 279 1 1
MAVS SNX8 0 0 251 251 1 1
MAVS PEX7 0 0 120 175 1 1
MAVS ATG9A 0 0 226 237 1 2
MAVS NMRAL1 0 0 212 212 1 1
MAVS ITGAX 0 0 323 323 1 1
MAVS NKRF 0 0 43 465 1 1
MAVS SLC32A1 0 0 122 239 1 1
MAVS SAMHD1 0 0 458 457 1 1
MAVS UBE2N 0 0 323 371 1 1
MAVS LRRC59 0 0 161 161 1 1
MAVS KLRK1 0 0 181 181 1 1
MAVS CHUK 270 800 830 974 1 1
MAVS TRIM44 0 0 322 507 1 1
MAVS TLR5 0 0 342 356 1 1
MAVS TMLHE 0 0 82 158 1 1
MAVS NLRP11 0 0 213 222 1 1
MAVS FLOT2 271 0 0 271 1 1
MAVS KIDINS220 0 0 0 202 1 1
MAVS TRIM31 486 0 753 871 1 1
MAVS PI4KA 0 0 194 194 1 1
MAVS CIITA 0 0 261 261 1 1
MAVS ECSIT 270 0 518 657 1 1
MAVS NOD2 0 800 988 997 1 2
MAVS PTPRC 0 0 215 235 1 1
MAVS ADAD2 0 0 112 265 1 1
MAVS IFIT1B 0 0 181 187 1 1
MAVS MLKL 0 0 321 346 1 2
MAVS BCL10 0 0 818 818 1 1
MAVS UBE2L6 0 0 306 306 1 1
MAVS JOSD2 270 0 0 270 1 1
MAVS ATG16L1 0 0 545 555 1 2
MAVS LTBR 0 0 175 193 1 1
MAVS TOMM22 276 0 142 417 1 1
MAVS GABARAPL1 0 0 167 167 1 2
MAVS OCA2 0 0 310 309 1 1
MAVS PHB2 0 0 163 196 1 1
MAVS UNC93B1 0 0 401 464 1 1
MAVS NFS1 0 0 0 189 1 1
MAVS ICAM1 0 0 181 181 1 2
MAVS AKAP1 117 0 68 160 1 1
MAVS MXI1 0 0 128 190 1 1
MAVS RIPK1 0 800 923 986 1 2
MAVS TRIM68 0 0 103 176 1 1
MAVS MID1 0 0 108 176 1 1
MAVS CSF1 0 0 210 227 1 1
MAVS FASLG 0 0 180 179 1 1
MAVS TICAM1 270 0 683 767 1 2
MAVS YWHAE 0 0 458 458 1 1
MAVS MNDA 0 0 212 212 1 1
MAVS IFNK 0 0 101 334 1 1
MAVS SOCS3 0 0 322 355 1 1
MAVS DDX24 0 0 342 368 1 1
MAVS ADARB2 0 0 184 190 1 1
MAVS PQBP1 0 0 182 187 1 1
MAVS CLEC6A 0 0 160 159 1 1
MAVS DDX31 0 0 0 261 1 1
MAVS RTP4 0 0 134 193 1 1
MAVS CCR5 0 0 194 194 1 1
MAVS CD69 0 0 155 154 1 1
MAVS MIB2 270 0 461 589 1 1
MAVS SOD1 130 0 123 204 1 2
MAVS RNF34 297 0 206 504 1 1
MAVS STAT5A 0 0 94 162 1 1
MAVS KPNA2 0 0 134 156 1 1
MAVS USP4 270 0 242 423 1 1
MAVS TMC8 0 0 0 155 1 1
MAVS FAF1 0 0 162 161 1 1
MAVS TNIP1 0 0 123 156 1 1
MAVS IRAK3 0 0 195 223 1 1
MAVS DTX4 0 0 294 294 1 1
MAVS XAF1 0 0 167 167 1 1
MAVS IFNL3 0 0 519 552 1 1
MAVS OTUD4 270 0 134 417 1 1
MAVS COPS6 270 0 0 270 1 1
MAVS FANCA 0 0 0 189 1 1
MAVS PSMB8 0 0 113 192 1 1
MAVS SYNJ2BP 0 0 235 257 1 1
MAVS MFN1 486 800 983 998 1 2
MAVS SH3RF2 0 0 54 274 1 1
MAVS MID2 0 0 143 246 1 1
MAVS XRN1 0 0 234 234 1 1
MAVS EIF2AK2 270 0 456 611 1 2
MAVS HAVCR2 0 0 141 233 1 1
MAVS CD8A 0 0 465 465 1 1
MAVS BTRC 0 0 183 193 1 1
MAVS FUNDC1 0 0 195 195 1 2
MAVS CALR 63 0 161 180 1 1
MAVS BAIAP2L1 0 0 175 194 1 1
MAVS RNF13 0 0 113 267 1 1
MAVS RIPK2 415 0 505 702 1 2
MAVS DCP1A 0 0 150 156 1 1
MAVS RNF122 0 0 310 309 1 1
MAVS TNFRSF13C 0 0 234 234 1 1
MAVS PRKACB 270 0 0 270 1 1
MAVS IFNGR1 0 0 324 333 1 1
MAVS ZC3HAV1 117 0 335 388 1 1
MAVS OTUD7B 270 0 204 394 1 1
MAVS MVP 0 0 135 221 1 1
MAVS SNAP29 0 0 156 174 1 2
MAVS BECN1 0 0 930 930 1 2
MAVS TRIM38 0 0 342 379 1 1
MAVS SNCA 0 0 123 152 1 2
MAVS TRIM6 0 0 292 303 1 1
MAVS CASP1 0 0 605 647 1 2
MAVS SCO1 420 0 0 420 1 1
MAVS FOXI2 0 0 57 218 1 1
MAVS TLR6 0 0 323 354 1 1
MAVS IL2 0 0 258 258 1 1
MAVS PEX16 0 0 127 154 1 1
MAVS UBXN4 117 0 63 157 1 1
MAVS PIAS1 0 0 193 193 1 1
MAVS VAC14 184 0 0 183 1 1
MAVS IFITM5 0 0 170 190 1 1
MAVS MEX3C 0 0 391 404 1 1
MAVS PMAIP1 0 0 234 234 1 2
MAVS TLR2 0 0 518 539 1 2
MAVS TNFSF10 0 0 231 230 1 2
MAVS LILRA4 0 0 170 169 1 1
MAVS PPM1A 0 0 194 265 1 1
MAVS SH2D3C 0 0 441 456 1 1
MAVS USP35 270 0 70 392 1 1
MAVS PHB 0 0 180 179 1 1
MAVS TRAF3 917 800 989 999 1 2
MAVS HSH2D 0 0 167 167 1 1
MAVS WDR5 270 0 95 311 1 1
MAVS CD86 0 0 294 294 1 1
MAVS IL10RA 0 0 128 153 1 1
MAVS TRIM17 0 0 232 244 1 1
MAVS MTHFD2 0 0 54 312 1 1
MAVS LZTS3 0 0 89 189 1 1
MAVS AMFR 270 0 322 484 1 1
MAVS TBKBP1 0 0 459 459 1 1
MAVS SIGLEC1 0 0 150 176 1 1
MAVS USP20 0 0 182 181 1 1
MAVS ENSG00000173366 0 0 650 682 1 1
MAVS SHARPIN 0 0 254 254 1 1
MAVS PFAS 0 0 134 163 1 1
MAVS JUN 0 0 392 392 1 2
MAVS DHX15 0 0 805 834 1 1
MAVS RHOT1 0 0 162 192 1 1
MAVS CD81 0 0 324 323 1 1
MAVS TYK2 0 0 467 498 1 1
MAVS TRIM11 0 0 206 237 1 1
MAVS IFNA17 0 0 370 371 1 1
MAVS NOD1 0 0 877 882 1 2
MAVS CARD11 0 0 243 244 1 1
MAVS TMEM173 870 800 848 995 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0050700 Molecular Function CARD domain binding enables IPI
GO:0039552 Molecular Function RIG-I binding enables IDA
GO:0042802 Molecular Function identical protein binding enables IDA
GO:0060090 Molecular Function molecular adaptor activity enables IDA
GO:0140693 Molecular Function molecular condensate scaffold activity enables IDA
GO:0005515 Molecular Function protein binding enables IPI
GO:0019901 Molecular Function protein kinase binding enables IPI
GO:0035591 Molecular Function signaling adaptor activity enables IDA
GO:0035591 Molecular Function signaling adaptor activity enables IMP
GO:0002218 Biological Process activation of innate immune response involved_in IDA
GO:0002218 Biological Process activation of innate immune response involved_in IMP
GO:0140374 Biological Process antiviral innate immune response involved_in IDA
GO:0071360 Biological Process cellular response to exogenous dsRNA involved_in IMP
GO:0002753 Biological Process cytoplasmic pattern recognition receptor signaling pathway involved_in IDA
GO:0042742 Biological Process defense response to bacterium involved_in IMP
GO:0051607 Biological Process defense response to virus involved_in IDA
GO:0051607 Biological Process defense response to virus involved_in NAS
GO:0045087 Biological Process innate immune response acts_upstream_of_positive_effect IDA
GO:0045087 Biological Process innate immune response involved_in IMP
GO:0045071 Biological Process negative regulation of viral genome replication involved_in IDA
GO:0051091 Biological Process positive regulation of DNA-binding transcription factor activity involved_in IDA
GO:0071660 Biological Process positive regulation of IP-10 production involved_in IDA
GO:1900227 Biological Process positive regulation of NLRP3 inflammasome complex assembly involved_in IDA
GO:0043123 Biological Process positive regulation of canonical NF-kappaB signal transduction involved_in HMP
GO:0071651 Biological Process positive regulation of chemokine (C-C motif) ligand 5 production involved_in IDA
GO:0002230 Biological Process positive regulation of defense response to virus by host involved_in IDA
GO:0002230 Biological Process positive regulation of defense response to virus by host involved_in IMP
GO:0032727 Biological Process positive regulation of interferon-alpha production involved_in IDA
GO:0032727 Biological Process positive regulation of interferon-alpha production involved_in IMP
GO:0032728 Biological Process positive regulation of interferon-beta production involved_in IDA
GO:0032728 Biological Process positive regulation of interferon-beta production involved_in IMP
GO:0032755 Biological Process positive regulation of interleukin-6 production involved_in IMP
GO:0032757 Biological Process positive regulation of interleukin-8 production involved_in IDA
GO:0002735 Biological Process positive regulation of myeloid dendritic cell cytokine production involved_in ISS
GO:0042307 Biological Process positive regulation of protein import into nucleus involved_in IDA
GO:0001934 Biological Process positive regulation of protein phosphorylation involved_in IDA
GO:0060760 Biological Process positive regulation of response to cytokine stimulus involved_in IMP
GO:0045944 Biological Process positive regulation of transcription by RNA polymerase II involved_in IDA
GO:0032760 Biological Process positive regulation of tumor necrosis factor production involved_in IDA
GO:0032760 Biological Process positive regulation of tumor necrosis factor production involved_in IMP
GO:0032481 Biological Process positive regulation of type I interferon production involved_in IDA
GO:0060340 Biological Process positive regulation of type I interferon-mediated signaling pathway involved_in IDA
GO:0070585 Biological Process protein localization to mitochondrion involved_in IDA
GO:1900063 Biological Process regulation of peroxisome organization involved_in IMP
GO:0007165 Biological Process signal transduction involved_in IMP
GO:0060337 Biological Process type I interferon-mediated signaling pathway involved_in NAS
GO:0031966 Cellular Component mitochondrial membrane located_in IDA
GO:0005741 Cellular Component mitochondrial outer membrane is_active_in IDA
GO:0005741 Cellular Component mitochondrial outer membrane located_in IDA
GO:0005741 Cellular Component mitochondrial outer membrane located_in TAS
GO:0005739 Cellular Component mitochondrion is_active_in IDA
GO:0005739 Cellular Component mitochondrion located_in IDA
GO:0005778 Cellular Component peroxisomal membrane located_in IDA
GO:0000151 Cellular Component ubiquitin ligase complex part_of NAS
Pathways
Name DB ID
Disease Reactome R-HSA-1643685
Innate Immune System Reactome R-HSA-168249
Immune System Reactome R-HSA-168256
DDX58/IFIH1-mediated induction of interferon-alpha/beta Reactome R-HSA-168928
Metabolism of proteins Reactome R-HSA-392499
Infectious disease Reactome R-HSA-5663205
Deubiquitination Reactome R-HSA-5688426
Ovarian tumor domain proteases Reactome R-HSA-5689896
Post-translational protein modification Reactome R-HSA-597592
TRAF3-dependent IRF activation pathway Reactome R-HSA-918233
TRAF6 mediated IRF7 activation Reactome R-HSA-933541
TRAF6 mediated NF-kB activation Reactome R-HSA-933542
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 Reactome R-HSA-933543
Negative regulators of DDX58/IFIH1 signaling Reactome R-HSA-936440
SARS-CoV-1 Infection Reactome R-HSA-9678108
SARS-CoV Infections Reactome R-HSA-9679506
SARS-CoV-1-host interactions Reactome R-HSA-9692914
SARS-CoV-1 activates/modulates innate immune responses Reactome R-HSA-9692916
SARS-CoV-2 Infection Reactome R-HSA-9694516
SARS-CoV-2 activates/modulates innate and adaptive immune responses Reactome R-HSA-9705671
SARS-CoV-2-host interactions Reactome R-HSA-9705683
Viral Infection Pathways Reactome R-HSA-9824446
mRNA vaccine activation of dendritic cell and induction of IFN-1 (WP5187) WikiPathways WP5187_r122433
Network map of SARS-CoV-2 signaling pathway (WP5115) WikiPathways WP5115_r124648
Measles virus infection (WP4630) WikiPathways WP4630_r123414
Hepatitis B infection (WP4666) WikiPathways WP4666_r123495
SARS-CoV-2 B.1.1.7 variant antagonises innate immune activation (WP5116) WikiPathways WP5116_r124652
SARS coronavirus and innate immunity (WP4912) WikiPathways WP4912_r124650
Type I interferon induction and signaling during SARS-CoV-2 infection (WP4868) WikiPathways WP4868_r124657
SARS-CoV-2 innate immunity evasion and cell-specific immune response (WP5039) WikiPathways WP5039_r124653
Mitochondrial immune response to SARS-CoV-2 (WP5038) WikiPathways WP5038_r124641
SARS-CoV-2 mitochondrial chronic oxidative stress and endothelial dysfunction (WP5183) WikiPathways WP5183_r124655
Cytosolic DNA-sensing pathway (WP4655) WikiPathways WP4655_r123496
Host-pathogen interaction of human coronaviruses - interferon induction (WP4880) WikiPathways WP4880_r124638
Novel intracellular components of RIG-I-like receptor pathway (WP3865) WikiPathways WP3865_r123636
Pathways of nucleic acid metabolism and innate immune sensing (WP4705) WikiPathways WP4705_r123423
Transcripts
Accession Version MolecularType Name NCBI Comments
NR_037921 2 miscRNA transcript variant 2 NC_000020 Reference
NM_001385663 1 mRNA transcript variant 4 NC_000020 Reference
NM_020746 5 mRNA transcript variant 1 NC_000020 Reference
NM_001206491 2 mRNA transcript variant 3 NC_000020 Reference