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BAK1

BCL2 antagonist/killer 1
General Information
Name BCL2 antagonist/killer 1
Alias
  • bcl-2 homologous antagonist/killer
  • BCL2-like 7 protein
  • apoptosis regulator BAK
  • bcl-2-like protein 7
  • bcl2-L-7
  • pro-apoptotic protein BAK
Gene_family BCL2 family
organism Homo sapiens
entrez_id 578
location 6p21.31
transcript_count 5
exon_count 9
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008]
    Stringdb Bcl-2 homologous antagonist/killer; In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti- apoptotic action of BCL2 or its adenovirus homolog E1B 19k protein. Low micromolar levels of zinc ions inhibit the promotion of apoptosis; Belongs to the Bcl-2 family
    nextProt Plays a role in the mitochondrial apoptosic process. Upon arrival of cell death signals, promotes mitochondrial outer membrane (MOM) permeabilization by oligomerizing to form pores within the MOM. This releases apoptogenic factors into the cytosol, including cytochrome c, promoting the activation of caspase 9 which in turn processes and activates the effector caspases.
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
BAK1 BioGRID BIK GeneID BioGRID Negative Genetic
BAK1 BioGRID BID GeneID BioGRID Negative Genetic; Protein-peptide
BAK1 BioGRID BAX GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Negative Genetic
BAK1 BioGRID BAD GeneID BioGRID Negative Genetic
BAK1 BioGRID HRK GeneID BioGRID Negative Genetic
BAK1 BioGRID BOK GeneID BioGRID Negative Genetic
BAK1 BioGRID BNIP3L GeneID BioGRID Negative Genetic
BAK1 BioGRID BMF GeneID BioGRID Negative Genetic
BAK1 BioGRID BCL2L11 GeneID BioGRID Negative Genetic
BAK1 BioGRID ORF1ab GeneID BioGRID Affinity Capture-Western
BAK1 BioGRID MCL1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Protein-peptide; Reconstituted Complex; Two-hybrid
BAK1 BioGRID BCL2L10 GeneID BioGRID Affinity Capture-Western
BAK1 BioGRID VDAC2 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
BAK1 BioGRID BCL2L1 GeneID BioGRID Affinity Capture-Luminescence; Affinity Capture-MS; Affinity Capture-Western; FRET; Protein-peptide; Reconstituted Complex; Two-hybrid
BAK1 BioGRID AMY1C GeneID BioGRID Affinity Capture-MS
BAK1 BioGRID A2ML1 GeneID BioGRID Affinity Capture-MS
BAK1 BioGRID TP53 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Reconstituted Complex
BAK1 BioGRID BCL2 GeneID BioGRID Affinity Capture-Western; Protein-peptide
BAK1 BioGRID FASN GeneID BioGRID Positive Genetic
BAK1 BioGRID MAPK8 GeneID BioGRID Affinity Capture-Western
BAK1 BioGRID BCL2L2 GeneID BioGRID Affinity Capture-Western; Two-hybrid
BAK1 BioGRID BCL2A1 GeneID BioGRID Two-hybrid
BAK1 BioGRID VIRMA GeneID BioGRID Affinity Capture-MS
BAK1 BioGRID RNF4 GeneID BioGRID Affinity Capture-MS
BAK1 BioGRID ND5 GeneID BioGRID Affinity Capture-Western
BAK1 BioGRID GIMAP5 GeneID BioGRID Affinity Capture-Western
BAK1 BioGRID HERC1 GeneID BioGRID Co-localization; Protein-peptide
BAK1 BioGRID BMH1 GeneID BioGRID Reconstituted Complex
BAK1 BioGRID NFKBIB GeneID BioGRID Biochemical Activity
BAK1 BioGRID HSD17B4 GeneID BioGRID Two-hybrid
BAK1 BioGRID TOMM7 GeneID BioGRID Co-fractionation
BAK1 BioGRID ABCB10 GeneID BioGRID Co-fractionation
BAK1 BioGRID TOMM40 GeneID BioGRID Co-fractionation
BAK1 BioGRID DBN1 GeneID BioGRID Two-hybrid
BAK1 BioGRID ARHGDIA GeneID BioGRID Two-hybrid
BAK1 Protein MFN1 GeneID HPRD
BAK1 Protein MCL1 GeneID HPRD
BAK1 Protein BCL2L10 GeneID HPRD
BAK1 Protein VDAC1 GeneID HPRD
BAK1 Protein ERN1 GeneID HPRD
BAK1 Protein BID GeneID HPRD
BAK1 Protein BCL2A1 GeneID HPRD
BAK1 Protein BAK1 GeneID HPRD
BAK1 Protein BAX GeneID HPRD
BAK1 Protein BCL2L1 GeneID HPRD
BAK1 Protein VDAC2 GeneID HPRD
BAK1 Protein TP53 GeneID HPRD
BAK1 Protein BCL2 GeneID HPRD
BAK1 Protein HSPD1 GeneID HPRD
BAK1 BioGRID HSPD1 GeneID BioGRID Affinity Capture-Western
BAK1 BioGRID FRYL GeneID BioGRID Affinity Capture-MS
BAK1 BioGRID SRRM2 GeneID BioGRID Affinity Capture-MS
BAK1 BioGRID MYCBP2 GeneID BioGRID Affinity Capture-MS
BAK1 BioGRID AKAP13 GeneID BioGRID Affinity Capture-MS
BAK1 BioGRID ACTR2 GeneID BioGRID Affinity Capture-MS
BAK1 BioGRID KRT31 GeneID BioGRID Affinity Capture-MS
BAK1 BioGRID FBL GeneID BioGRID Affinity Capture-MS
BAK1 BioGRID DFFA GeneID BioGRID Affinity Capture-MS
BAK1 BioGRID BAK1 GeneID BioGRID Affinity Capture-Western
BAK1 Protein BAK1 GeneID BIND BAK1 (Bak) interacts with itself to form a dimer.
BAK1 Protein TP53 GeneID BIND Mitochondrial p53-P72 interacts with Bak.
BAK1 Protein TP53 GeneID BIND Mitochondrial p53-R72 interacts with Bak.
StringDB
A B experiments database textmining combined score hadb nhadb
BAK1 JUN 0 0 310 309 1 2
BAK1 LOH12CR1 0 0 0 189 1 1
BAK1 GTF2H3 0 0 73 174 1 1
BAK1 RHOT1 0 0 50 241 1 1
BAK1 DAPK1 0 0 298 330 1 2
BAK1 UBA6 0 0 0 174 1 1
BAK1 BCL2L11 878 900 635 995 1 2
BAK1 SCRN2 0 0 0 191 1 1
BAK1 TNFSF10 0 0 370 370 1 2
BAK1 DHRS11 0 0 0 171 1 1
BAK1 ULK2 0 0 107 173 1 2
BAK1 BOK 0 0 556 565 1 1
BAK1 PIK3CG 0 0 158 202 1 1
BAK1 BAG5 0 0 145 388 1 1
BAK1 GTF2H4 0 0 46 272 1 1
BAK1 DNTT 0 0 206 206 1 1
BAK1 CHEK1 0 0 149 167 1 2
BAK1 SCO1 0 0 0 227 1 1
BAK1 CASP1 0 0 263 391 1 2
BAK1 COX15 0 0 0 181 1 1
BAK1 CCNA2 0 0 150 157 1 1
BAK1 RIPK2 0 0 231 268 1 2
BAK1 TFAM 0 0 141 202 1 2
BAK1 WBSCR16 0 0 0 171 1 1
BAK1 POFUT2 0 0 0 379 1 1
BAK1 TCIRG1 0 0 53 158 1 1
BAK1 CYB5B 0 0 0 156 1 1
BAK1 MFN1 486 0 453 791 1 2
BAK1 DND1 0 0 244 251 1 1
BAK1 MOB2 0 0 75 188 1 1
BAK1 TSTD2 0 0 68 220 1 1
BAK1 BIK 0 0 529 542 1 2
BAK1 CALR 0 0 143 177 1 1
BAK1 DEFA6 0 0 56 153 1 1
BAK1 CDC25C 0 0 150 203 1 2
BAK1 SOD1 44 0 123 155 1 2
BAK1 CENPE 0 0 91 288 1 1
BAK1 STOML2 0 0 0 153 1 1
BAK1 NFKBIE 0 0 0 197 1 1
BAK1 TICAM1 0 0 112 247 1 2
BAK1 IGFBP4 0 0 430 430 1 1
BAK1 CAPN2 0 800 137 826 1 2
BAK1 NDUFA3 0 0 0 239 1 1
BAK1 ATF7IP 0 0 595 602 1 1
BAK1 HOMEZ 0 0 91 169 1 1
BAK1 HBS1L 0 0 162 219 1 1
BAK1 GABARAPL1 0 0 129 183 1 2
BAK1 TRAPPC4 0 0 0 183 1 1
BAK1 NFS1 0 0 0 288 1 1
BAK1 ZEB1 0 0 189 189 1 2
BAK1 PEAR1 0 0 156 170 1 1
BAK1 BCL2L12 0 0 155 256 1 1
BAK1 RAB35 0 0 0 151 1 1
BAK1 MLKL 0 0 204 221 1 2
BAK1 BCL10 0 0 204 209 1 1
BAK1 IGFBP2 0 0 323 323 1 1
BAK1 CXCL12 0 0 112 167 1 2
BAK1 BAX 753 900 732 981 1 2
BAK1 TPM1 0 0 175 193 1 1
BAK1 TMLHE 0 0 0 303 1 1
BAK1 TOMM40 627 540 65 837 1 1
BAK1 EPCAM 0 0 53 206 1 2
BAK1 EIF4G1 0 0 81 161 1 2
BAK1 AR 0 0 210 223 1 2
BAK1 ABTB1 0 0 235 262 1 1
BAK1 PARP1 0 0 165 166 1 2
BAK1 BID 808 900 602 993 1 2
BAK1 IER3IP1 0 0 81 179 1 1
BAK1 ATG9A 0 0 148 155 1 2
BAK1 RAB24 0 0 181 244 1 2
BAK1 CDKN1A 0 0 303 320 1 2
BAK1 BNIP3 0 0 373 393 1 2
BAK1 SQSTM1 0 0 210 210 1 2
BAK1 CAPN12 0 0 167 224 1 1
BAK1 SIRT3 0 0 113 329 1 2
BAK1 B2M 0 0 150 173 1 1
BAK1 MMP9 0 0 126 175 1 2
BAK1 MAPK3 0 0 160 202 1 2
BAK1 CAMK2N2 0 0 84 181 1 1
BAK1 DLST 0 0 0 304 1 1
BAK1 DNMT1 0 0 152 151 1 2
BAK1 PRDM14 0 0 234 267 1 1
BAK1 SPG7 0 720 0 748 1 1
BAK1 SLC25A44 0 0 134 157 1 1
BAK1 ACTB 0 0 360 402 1 2
BAK1 AK2 0 0 0 190 1 1
BAK1 COX4I1 0 0 125 215 1 1
BAK1 TP73 0 0 309 309 1 2
BAK1 SGPL1 0 0 134 209 1 1
BAK1 RAB29 0 0 0 307 1 1
BAK1 HTRA2 0 0 302 407 1 1
BAK1 CEBPA 0 0 140 158 1 1
BAK1 COQ7 0 0 0 363 1 1
BAK1 STK11IP 0 0 103 233 1 1
BAK1 ATP5S 0 0 0 228 1 1
BAK1 TOR1B 0 0 0 204 1 1
BAK1 NCLN 0 0 0 175 1 1
BAK1 MRPS10 0 0 0 183 1 1
BAK1 E2F7 0 0 82 163 1 1
BAK1 HSP90AA1 0 0 210 225 1 2
BAK1 BCL9 0 0 53 193 1 1
BAK1 CASP7 0 0 418 531 1 1
BAK1 CLPTM1L 0 0 376 563 1 1
BAK1 CARD17 0 0 0 208 1 1
BAK1 IFI6 0 0 130 167 1 1
BAK1 ALB 0 0 153 160 1 2
BAK1 CASP8 0 0 592 667 1 2
BAK1 PMF1 0 0 160 289 1 1
BAK1 PPP2R1B 0 0 134 179 1 1
BAK1 LRRFIP1 0 0 103 196 1 1
BAK1 CCL2 0 0 142 155 1 2
BAK1 ANXA8 0 0 181 181 1 1
BAK1 BIRC3 0 0 322 405 1 1
BAK1 ONECUT1 0 0 306 306 1 1
BAK1 NAIF1 0 0 113 434 1 1
BAK1 DRAM2 0 0 218 238 1 2
BAK1 ERO1L 0 0 161 289 1 1
BAK1 BLVRB 0 0 45 220 1 1
BAK1 TARBP2 0 0 54 179 1 1
BAK1 TP53AIP1 0 0 167 167 1 1
BAK1 MAD1L1 0 0 287 324 1 1
BAK1 MLLT4 0 720 0 720 1 1
BAK1 TNFRSF10A 0 0 244 263 1 1
BAK1 STK35 0 0 108 351 1 1
BAK1 SIRPA 0 0 60 154 1 1
BAK1 TROVE2 0 0 0 181 1 1
BAK1 AUP1 0 0 53 284 1 1
BAK1 TEFM 0 0 0 307 1 1
BAK1 TMEM126A 0 0 0 307 1 1
BAK1 BCL2L13 0 0 322 341 1 2
BAK1 C8B 0 720 0 727 1 1
BAK1 BUB1B 0 0 73 150 1 1
BAK1 CDH1 0 0 232 231 1 2
BAK1 BCL2L10 213 0 470 576 1 1
BAK1 EMC6 0 0 0 183 1 1
BAK1 RMDN1 0 0 0 247 1 1
BAK1 PPOX 0 0 0 302 1 1
BAK1 DUT 0 0 0 203 1 1
BAK1 FKBP4 0 0 52 209 1 1
BAK1 SLC25A30 0 0 95 173 1 1
BAK1 CDK6 0 0 261 349 1 2
BAK1 DNM2 0 0 0 261 1 1
BAK1 ERCC4 0 0 49 169 1 1
BAK1 SUN1 0 0 0 191 1 1
BAK1 TRADD 0 0 305 430 1 1
BAK1 PPP1CB 0 0 193 311 1 1
BAK1 DCTN3 0 0 81 152 1 1
BAK1 BDH2 0 0 0 154 1 1
BAK1 SRCIN1 0 0 150 235 1 1
BAK1 MAP3K11 0 0 86 152 1 1
BAK1 XRCC4 0 0 323 323 1 1
BAK1 ATG16L2 0 0 185 201 1 2
BAK1 HIBADH 0 0 0 378 1 1
BAK1 GRINA 0 0 138 263 1 1
BAK1 XPNPEP2 0 0 63 165 1 1
BAK1 MX2 0 0 54 246 1 1
BAK1 PPP2CB 0 0 0 165 1 1
BAK1 LENG1 0 0 59 415 1 1
BAK1 NDUFS7 0 0 0 269 1 1
BAK1 EMC3 0 0 0 179 1 1
BAK1 IFIH1 0 0 92 167 1 1
BAK1 EMC2 0 0 122 205 1 1
BAK1 DIABLO 0 900 459 946 1 2
BAK1 NDUFS5 0 0 0 272 1 1
BAK1 ARHGEF3 0 0 181 262 1 1
BAK1 CTDSPL 0 0 138 161 1 1
BAK1 MRPS25 0 0 0 181 1 1
BAK1 MYLPF 0 0 0 154 1 1
BAK1 TRAPPC10 0 0 0 228 1 1
BAK1 PHF8 0 0 46 168 1 1
BAK1 PTK2 0 0 74 208 1 2
BAK1 UTS2R 0 0 103 180 1 1
BAK1 MAPK8 270 0 243 449 1 2
BAK1 SEC61G 0 0 0 187 1 1
BAK1 IGFBP1 0 0 430 430 1 1
BAK1 SLC25A17 0 0 46 210 1 1
BAK1 EGF 0 0 166 165 1 2
BAK1 BFAR 0 0 107 172 1 1
BAK1 ETS1 0 0 155 154 1 1
BAK1 NDUFB9 0 0 0 212 1 1
BAK1 NANOG 0 0 178 177 1 2
BAK1 IL18BP 0 0 52 198 1 1
BAK1 KLF13 0 0 315 341 1 1
BAK1 CASP9 0 0 595 662 1 2
BAK1 ATG4A 0 0 123 177 1 2
BAK1 TRAF6 0 0 202 221 1 2
BAK1 CYCS 0 900 607 963 1 2
BAK1 PLK2 0 0 82 176 1 1
BAK1 OGG1 0 0 0 188 1 1
BAK1 CHEK2 0 0 136 163 1 1
BAK1 MAPK9 0 0 134 178 1 2
BAK1 PDCD4 0 0 244 248 1 2
BAK1 XPO5 0 0 181 198 1 1
BAK1 HSP90B1 0 0 211 244 1 1
BAK1 PEX11B 0 0 0 183 1 1
BAK1 IER3 0 0 90 154 1 1
BAK1 SEPT9 0 0 0 156 1 1
BAK1 HSPA4 0 0 167 167 1 1
BAK1 C9 0 720 0 720 1 1
BAK1 DICER1 0 0 278 278 1 1
BAK1 IGF1R 0 0 203 203 1 2
BAK1 VARS2 0 0 0 152 1 1
BAK1 GPSM3 0 0 90 197 1 1
BAK1 SDHC 0 0 91 353 1 1
BAK1 NDUFA11 0 0 0 270 1 1
BAK1 LHFPL5 0 0 614 614 1 1
BAK1 H1F0 0 0 296 296 1 1
BAK1 ADAM10 0 720 0 720 1 1
BAK1 RIT1 0 0 86 334 1 1
BAK1 UCK2 0 0 170 188 1 1
BAK1 KISS1R 0 0 54 189 1 1
BAK1 MRPS11 0 0 0 183 1 1
BAK1 MYC 0 0 350 379 1 2
BAK1 IRGM 0 0 181 221 1 2
BAK1 PARK2 0 0 95 167 1 1
BAK1 CCNH 0 0 165 175 1 1
BAK1 NDUFS6 0 0 51 155 1 1
BAK1 TRAPPC9 0 0 0 385 1 1
BAK1 PIK3CA 0 0 134 168 1 2
BAK1 EMC4 0 0 0 183 1 1
BAK1 TRAF2 0 0 171 177 1 2
BAK1 MX1 0 0 123 304 1 1
BAK1 TMBIM6 0 800 181 832 1 1
BAK1 ENSG00000261832 0 0 167 219 1 1
BAK1 CASP10 0 0 327 451 1 1
BAK1 HIST1H1A 0 0 387 386 1 1
BAK1 PTPMT1 0 0 75 184 1 1
BAK1 KRTCAP2 0 0 0 157 1 1
BAK1 NDUFB7 0 0 0 443 1 1
BAK1 FXN 0 0 0 183 1 1
BAK1 MOAP1 0 0 136 163 1 1
BAK1 NDUFS3 0 0 0 154 1 1
BAK1 NOL3 0 0 324 342 1 1
BAK1 NKIRAS2 0 0 174 365 1 1
BAK1 CIDEB 0 0 155 167 1 1
BAK1 PHLDA3 0 0 64 385 1 1
BAK1 BRCA1 0 0 181 198 1 2
BAK1 PITX1 0 0 153 184 1 1
BAK1 CYB5A 0 0 0 159 1 1
BAK1 CAND1 0 0 129 264 1 1
BAK1 MAP2K1 0 0 150 169 1 1
BAK1 OPA1 0 0 0 267 1 2
BAK1 PPIF 0 720 270 800 1 1
BAK1 C5 0 720 0 720 1 1
BAK1 ST13 0 0 44 176 1 2
BAK1 RB1CC1 0 0 125 208 1 2
BAK1 PGAM5 0 0 166 218 1 1
BAK1 SLC25A19 0 0 93 213 1 1
BAK1 CIDEA 0 0 148 167 1 1
BAK1 RPS19 0 0 350 349 1 1
BAK1 AKT2 0 0 124 235 1 2
BAK1 ACBD5 0 0 67 169 1 2
BAK1 FADD 0 0 459 509 1 2
BAK1 MYD88 0 0 95 185 1 2
BAK1 PPP1CC 0 0 0 160 1 1
BAK1 CDK4 0 0 218 275 1 2
BAK1 CFLAR 0 0 324 436 1 2
BAK1 EGFR 0 0 255 263 1 2
BAK1 TGM2 0 0 90 165 1 2
BAK1 TP53 836 900 833 997 1 2
BAK1 MDM2 0 0 294 305 1 2
BAK1 BNIP2 0 0 296 329 1 1
BAK1 DAZL 0 0 215 244 1 1
BAK1 NME3 0 0 0 329 1 1
BAK1 DDIT3 0 0 283 282 1 2
BAK1 CRADD 0 0 260 334 1 1
BAK1 TNFRSF11B 0 0 143 258 1 1
BAK1 MAP1A 0 0 154 172 1 2
BAK1 GZMH 0 0 74 171 1 1
BAK1 UQCRH 0 0 0 377 1 1
BAK1 NCOR2 0 0 166 184 1 1
BAK1 IRAK1 0 0 140 185 1 1
BAK1 TXK 0 0 254 254 1 1
BAK1 TRAF1 0 0 145 162 1 1
BAK1 FAM210A 0 0 0 309 1 1
BAK1 ARMC1 0 0 0 275 1 1
BAK1 HUWE1 0 0 113 171 1 1
BAK1 MSTO1 0 0 112 186 1 1
BAK1 TEX14 0 0 391 404 1 1
BAK1 HGS 0 0 107 168 1 2
BAK1 PLA2G4C 0 0 117 222 1 1
BAK1 JAK2 0 0 120 175 1 2
BAK1 SKIV2L 0 0 56 169 1 1
BAK1 APAF1 0 900 562 980 1 2
BAK1 HDAC6 0 0 150 197 1 2
BAK1 AGO2 0 0 150 155 1 2
BAK1 SUCLG1 0 0 0 153 1 1
BAK1 RBBP6 0 0 102 196 1 1
BAK1 VDAC2 432 540 597 901 1 1
BAK1 CPT2 0 0 0 181 1 1
BAK1 STAT3 0 0 297 317 1 2
BAK1 EZH2 0 0 184 183 1 2
BAK1 PSMD13 0 0 96 236 1 1
BAK1 ERN1 213 0 307 453 1 2
BAK1 PRKAR2A 0 0 0 186 1 1
BAK1 CLN3 0 0 233 280 1 2
BAK1 KIAA1429 270 0 0 270 1 1
BAK1 NDUFS4 0 0 0 183 1 1
BAK1 HIF1A 0 0 193 221 1 2
BAK1 BAG3 0 0 337 369 1 2
BAK1 IL1B 0 0 203 209 1 2
BAK1 ZBTB9 0 0 403 430 1 1
BAK1 MYOM2 0 0 323 323 1 1
BAK1 DNM3 0 0 124 382 1 1
BAK1 UQCRB 0 0 0 210 1 1
BAK1 COQ9 0 0 0 274 1 1
BAK1 TNFRSF1B 0 0 163 198 1 1
BAK1 PNPT1 0 0 0 189 1 1
BAK1 TMEM14C 0 0 0 301 1 1
BAK1 PRKAR2B 0 0 48 204 1 1
BAK1 CDK2 0 0 248 306 1 2
BAK1 GIMAP5 270 0 0 282 1 1
BAK1 CTNNB1 0 0 233 236 1 2
BAK1 MAP1LC3A 0 0 161 195 1 2
BAK1 C7 0 720 0 724 1 1
BAK1 HRAS 0 0 216 235 1 2
BAK1 MFN2 486 0 357 757 1 2
BAK1 NDUFC2 0 0 0 307 1 1
BAK1 LAP3 0 0 145 181 1 1
BAK1 MTOR 0 0 242 255 1 2
BAK1 NLRP1 0 0 95 151 1 1
BAK1 ATP5D 0 0 0 228 1 1
BAK1 CISD1 0 0 47 192 1 1
BAK1 POTEF 0 0 213 249 1 1
BAK1 CXCR4 0 0 155 174 1 2
BAK1 CYR61 0 0 0 173 1 1
BAK1 CD40LG 0 0 123 259 1 1
BAK1 NOTCH1 0 0 175 209 1 2
BAK1 SCO2 0 0 0 175 1 1
BAK1 CCNC 0 0 134 191 1 1
BAK1 SFXN4 0 0 0 303 1 1
BAK1 STAT1 0 0 184 207 1 2
BAK1 ENDOG 0 0 257 318 1 1
BAK1 RAD51C 0 0 124 196 1 1
BAK1 BCL2L2-PABPN1 0 540 530 629 1 1
BAK1 GZMB 0 0 116 171 1 1
BAK1 TNFRSF1A 0 0 324 338 1 1
BAK1 PIK3C3 0 0 181 303 1 2
BAK1 UCP2 0 0 127 186 1 2
BAK1 F11R 0 0 49 212 1 1
BAK1 IL6 0 0 231 230 1 2
BAK1 AAMDC 0 0 0 183 1 1
BAK1 BCKDHB 0 0 0 183 1 1
BAK1 SLC25A10 0 0 61 223 1 1
BAK1 COX5A 0 0 68 163 1 1
BAK1 BIRC2 0 0 392 423 1 1
BAK1 TUBB1 0 0 140 162 1 1
BAK1 CREB1 0 0 134 151 1 2
BAK1 GSDMD 0 0 139 170 1 2
BAK1 SDHB 0 0 45 390 1 1
BAK1 LONP1 0 0 49 164 1 1
BAK1 TIMM22 0 0 0 378 1 1
BAK1 PLGRKT 0 0 0 179 1 1
BAK1 MINOS1 0 0 0 428 1 1
BAK1 DGCR8 0 0 164 163 1 1
BAK1 ATP5E 0 0 0 179 1 1
BAK1 ARF1 0 0 0 182 1 1
BAK1 PPID 0 0 155 169 1 1
BAK1 TNFSF18 0 0 94 150 1 1
BAK1 HSF1 0 0 70 194 1 2
BAK1 LMAN1 0 0 44 163 1 1
BAK1 PDE11A 0 0 302 302 1 1
BAK1 ZNF285 0 0 185 197 1 1
BAK1 ANXA5 0 0 391 403 1 2
BAK1 CCNB1 0 0 208 225 1 1
BAK1 CLPTM1 0 0 134 254 1 1
BAK1 PTGES2 0 0 0 297 1 1
BAK1 HSPD1 270 0 46 364 1 1
BAK1 TMEM199 0 0 0 426 1 1
BAK1 TOMM7 619 0 0 709 1 1
BAK1 NFKB1 0 0 244 314 1 2
BAK1 DNMT3A 0 0 123 152 1 2
BAK1 RELA 0 0 141 164 1 2
BAK1 BCL2L1 982 900 848 998 1 2
BAK1 C9orf69 0 0 0 155 1 1
BAK1 CCNJ 0 0 178 177 1 1
BAK1 KITLG 0 0 425 424 1 1
BAK1 COL11A2 0 0 386 386 1 1
BAK1 CASP6 0 0 370 474 1 1
BAK1 NDUFA12 0 0 58 197 1 1
BAK1 SLC25A20 0 0 50 170 1 1
BAK1 USP27X 0 0 90 152 1 1
BAK1 TFB1M 0 0 96 151 1 1
BAK1 GABARAPL2 0 0 113 208 1 2
BAK1 SMG1 0 0 358 382 1 1
BAK1 MAP2K7 0 0 203 349 1 1
BAK1 ABL1 0 0 108 164 1 1
BAK1 TUSC1 0 0 155 182 1 1
BAK1 KIAA0232 0 0 259 258 1 1
BAK1 SH2B3 0 0 181 217 1 1
BAK1 FGFR2 0 0 95 189 1 1
BAK1 TLR4 0 0 134 156 1 2
BAK1 KSR2 0 0 53 377 1 1
BAK1 GAPDH 0 0 335 335 1 2
BAK1 SLC25A11 0 0 0 212 1 1
BAK1 RIT2 0 0 0 218 1 1
BAK1 NDUFV2 0 0 0 229 1 1
BAK1 TNFRSF25 0 0 146 191 1 1
BAK1 BIN2 0 0 223 223 1 1
BAK1 SLFN13 0 0 95 151 1 1
BAK1 PDIA3 0 0 95 210 1 1
BAK1 NOD1 0 0 141 168 1 2
BAK1 TFG 0 0 0 195 1 1
BAK1 ACOX3 0 0 0 183 1 1
BAK1 PDZD11 0 720 0 720 1 1
BAK1 GFM2 0 0 0 393 1 1
BAK1 BCL2L15 0 0 235 242 1 1
BAK1 CDC25A 0 0 127 256 1 1
BAK1 TAOK1 0 0 164 185 1 1
BAK1 PMAIP1 0 0 564 622 1 2
BAK1 USMG5 0 0 0 183 1 1
BAK1 CDKN2B 0 0 150 163 1 1
BAK1 PEA15 0 0 123 268 1 1
BAK1 TRAF3 0 0 120 157 1 2
BAK1 CDKN2C 0 0 146 187 1 1
BAK1 KIAA2013 0 0 0 386 1 1
BAK1 ABCB1 0 0 163 163 1 2
BAK1 ENSG00000262660 0 0 61 183 1 1
BAK1 BECN1 312 0 390 678 1 2
BAK1 NDUFAF7 0 0 0 228 1 1
BAK1 EEF2K 0 0 48 154 1 2
BAK1 PEX16 0 0 0 309 1 1
BAK1 KRAS 0 0 182 192 1 2
BAK1 FOXO1 0 0 172 185 1 2
BAK1 MECR 0 0 0 386 1 1
BAK1 SOD2 0 0 165 190 1 2
BAK1 DNM1 0 0 0 245 1 1
BAK1 HSPA5 0 0 224 224 1 2
BAK1 UPF1 0 0 49 256 1 1
BAK1 CASP14 0 0 216 346 1 1
BAK1 GBP6 0 0 85 185 1 1
BAK1 BTRC 0 0 91 193 1 1
BAK1 ZNF346 0 0 195 195 1 1
BAK1 PDHX 0 0 72 180 1 1
BAK1 BIRC7 0 0 171 204 1 1
BAK1 TMEM11 0 0 0 273 1 1
BAK1 STAT5A 0 0 149 173 1 1
BAK1 PTPN11 0 0 74 150 1 1
BAK1 CBR4 0 0 0 323 1 1
BAK1 ROMO1 0 0 0 232 1 1
BAK1 FOS 0 0 161 161 1 2
BAK1 FASLG 0 0 371 371 1 1
BAK1 LMAN2L 0 0 0 272 1 1
BAK1 WDR59 0 0 0 245 1 1
BAK1 LTBR 0 0 154 260 1 1
BAK1 ATP5I 0 0 0 228 1 1
BAK1 HIGD1A 0 0 70 267 1 1
BAK1 HDAC1 0 0 150 181 1 2
BAK1 MAP3K10 0 0 95 151 1 1
BAK1 RIPK1 0 0 267 298 1 2
BAK1 PDIA4 0 0 127 191 1 1
BAK1 CEBPB 0 0 94 160 1 2
BAK1 ATG16L1 0 0 120 180 1 2
BAK1 NRM 0 0 0 294 1 1
BAK1 MEGF9 0 0 171 171 1 1
BAK1 NDUFS8 0 0 0 188 1 1
BAK1 CDKN2A 0 0 269 284 1 2
BAK1 CASP4 0 0 283 411 1 2
BAK1 MTCH2 0 0 75 162 1 1
BAK1 ADPGK 0 0 66 179 1 1
BAK1 GSK3B 0 0 130 156 1 2
BAK1 S100B 0 0 53 173 1 1
BAK1 ADCK1 0 0 123 170 1 1
BAK1 CTSS 0 0 166 229 1 1
BAK1 DCDC2 0 0 274 274 1 1
BAK1 ATG12 0 0 241 240 1 2
BAK1 TNFRSF10B 0 0 264 301 1 2
BAK1 MRPS16 0 0 0 159 1 1
BAK1 TNFRSF21 0 0 165 165 1 1
BAK1 PRELID1 0 0 0 218 1 1
BAK1 EEF1A1 0 0 276 280 1 1
BAK1 PTGS2 0 0 143 162 1 2
BAK1 ERBB3 0 0 214 214 1 1
BAK1 CASP3 0 0 596 669 1 2
BAK1 ARID3A 0 0 124 253 1 1
BAK1 NQO1 0 0 61 205 1 2
BAK1 ATG4D 0 0 187 228 1 2
BAK1 ATG101 0 0 75 182 1 2
BAK1 HSPB8 0 0 123 162 1 2
BAK1 PARS2 0 0 0 306 1 1
BAK1 CARD16 0 0 0 208 1 1
BAK1 NCAPH 0 0 0 181 1 1
BAK1 VEGFA 0 0 175 175 1 2
BAK1 GABARAP 0 0 125 179 1 2
BAK1 TXN2 0 0 59 159 1 1
BAK1 PTEN 0 0 336 360 1 2
BAK1 PANK2 0 0 0 189 1 1
BAK1 DNM1L 0 0 235 390 1 2
BAK1 CASP5 0 0 294 420 1 1
BAK1 IARS2 0 0 0 183 1 1
BAK1 SENP8 0 0 0 190 1 1
BAK1 RPS20 0 0 386 386 1 1
BAK1 TCF4 0 0 82 248 1 1
BAK1 AMBRA1 0 0 168 189 1 2
BAK1 TACSTD2 0 0 65 344 1 1
BAK1 RHOT2 0 0 74 223 1 1
BAK1 KIT 0 0 392 392 1 2
BAK1 MAPK14 0 0 155 155 1 2
BAK1 RFWD3 0 0 324 338 1 1
BAK1 TPD52L1 0 0 77 578 1 1
BAK1 TP53BP2 0 0 163 218 1 2
BAK1 BAG1 0 0 218 230 1 2
BAK1 E2F3 0 0 294 336 1 1
BAK1 SLC27A2 0 0 94 187 1 1
BAK1 JMJD1C 0 0 161 191 1 1
BAK1 CTSD 0 0 170 207 1 2
BAK1 PREB 0 0 0 183 1 1
BAK1 HIST1H1C 0 0 431 431 1 1
BAK1 ATM 0 0 211 220 1 2
BAK1 TOMM70A 0 0 0 273 1 1
BAK1 FRYL 130 0 74 159 1 1
BAK1 EFCAB12 0 0 180 301 1 1
BAK1 ATP5L 0 0 0 183 1 1
BAK1 PLEKHA7 0 720 0 724 1 1
BAK1 F8A1 0 0 0 228 1 1
BAK1 ATG7 0 0 218 236 1 2
BAK1 BTG2 0 0 145 182 1 1
BAK1 RCL1 0 0 233 249 1 1
BAK1 ACTG1 0 0 201 230 1 1
BAK1 WDR7 0 0 0 228 1 1
BAK1 MT-ND4 0 0 0 183 1 1
BAK1 SNAI1 0 0 210 225 1 1
BAK1 IL10 0 0 158 161 1 2
BAK1 NDUFA8 0 0 0 188 1 1
BAK1 CASP16 0 0 0 200 1 1
BAK1 TERT 0 0 324 337 1 2
BAK1 PIAS3 0 0 113 249 1 1
BAK1 DFFB 0 0 146 167 1 1
BAK1 NDUFB8 0 0 0 179 1 1
BAK1 MAP1LC3B 0 0 219 220 1 2
BAK1 DEFA4 0 0 54 151 1 1
BAK1 CANT1 0 0 82 169 1 1
BAK1 NFKBIB 270 0 73 305 1 1
BAK1 SPHK1 0 0 150 257 1 2
BAK1 THPO 0 0 152 151 1 1
BAK1 SEL1L 0 0 140 172 1 1
BAK1 CDC25B 0 0 0 151 1 1
BAK1 ULK1 0 0 141 194 1 2
BAK1 AMDHD2 0 0 0 214 1 1
BAK1 CARKD 0 0 0 245 1 1
BAK1 MED31 0 0 97 165 1 1
BAK1 COQ3 0 0 0 429 1 1
BAK1 AKT3 0 0 150 185 1 2
BAK1 TSPYL5 0 0 0 187 1 1
BAK1 C1orf50 0 0 0 219 1 1
BAK1 FUNDC2 0 0 0 248 1 1
BAK1 PBXIP1 0 0 0 179 1 1
BAK1 SPI1 0 0 150 187 1 1
BAK1 CTSB 0 0 181 187 1 2
BAK1 SIRT1 0 0 218 218 1 2
BAK1 MCL1 915 900 741 994 1 2
BAK1 MAP3K5 0 0 207 207 1 1
BAK1 TMEM55B 0 0 0 204 1 1
BAK1 DFNA5 0 0 134 205 1 1
BAK1 PDIK1L 0 0 0 215 1 1
BAK1 TSPAN33 0 720 0 720 1 1
BAK1 ESR1 0 0 219 249 1 2
BAK1 MSH2 0 0 123 187 1 1
BAK1 PPP1CA 0 0 180 396 1 1
BAK1 KSR1 0 0 0 189 1 1
BAK1 ATG5 0 0 266 275 1 2
BAK1 UQCRQ 0 0 0 181 1 1
BAK1 MT-ND1 0 0 0 301 1 1
BAK1 NDUFA2 0 0 0 270 1 1
BAK1 BCL2L14 0 0 321 333 1 1
BAK1 ITGB3 0 0 138 156 1 1
BAK1 TP63 0 0 270 270 1 2
BAK1 XBP1 0 0 306 306 1 2
BAK1 TNFAIP2 0 0 0 210 1 1
BAK1 IRF1 0 0 150 168 1 2
BAK1 IDH3B 0 0 0 152 1 1
BAK1 C22orf29 270 0 469 595 1 1
BAK1 ABHD10 0 0 0 159 1 1
BAK1 MFSD10 0 0 0 211 1 1
BAK1 HSPA13 0 0 156 155 1 1
BAK1 TNF 0 0 285 298 1 2
BAK1 RNF4 270 0 0 283 1 1
BAK1 TDG 0 0 126 158 1 1
BAK1 PNRC2 0 0 0 175 1 1
BAK1 WISP1 0 0 0 214 1 1
BAK1 CASP2 0 0 341 462 1 1
BAK1 C6 0 720 0 727 1 1
BAK1 CD44 0 0 170 188 1 2
BAK1 STARD13 0 0 181 227 1 1
BAK1 NME6 0 0 0 189 1 1
BAK1 NAIP 0 0 252 282 1 1
BAK1 RCAN1 0 0 108 163 1 2
BAK1 FIS1 0 0 143 164 1 2
BAK1 PDGFC 0 0 0 206 1 1
BAK1 DEFB108B 0 0 103 159 1 1
BAK1 PPP1R15A 0 0 212 229 1 2
BAK1 TNFAIP3 0 0 181 211 1 2
BAK1 C8G 0 540 0 540 1 1
BAK1 EDEM1 0 0 137 208 1 2
BAK1 ATG4B 0 0 161 204 1 2
BAK1 QPCTL 0 0 0 155 1 1
BAK1 CCND2 0 0 133 219 1 1
BAK1 CD70 0 0 118 170 1 1
BAK1 CCDC71L 0 0 146 170 1 1
BAK1 SFRP4 0 0 92 191 1 1
BAK1 BMF 0 0 561 610 1 1
BAK1 BCL2A1 919 0 501 964 1 1
BAK1 C1orf27 0 0 0 169 1 1
BAK1 DGUOK 0 0 0 303 1 1
BAK1 RELB 0 0 138 198 1 2
BAK1 DRAM1 0 0 244 284 1 2
BAK1 ABCB10 271 0 45 289 1 1
BAK1 TOMM5 0 0 0 183 1 1
BAK1 IFNW1 0 0 67 152 1 1
BAK1 SLC25A25 0 0 123 160 1 1
BAK1 GADD45A 0 0 277 277 1 1
BAK1 MRPS24 0 0 0 230 1 1
BAK1 RAB23 0 0 0 438 1 2
BAK1 SOCS1 0 0 150 233 1 1
BAK1 CCND3 0 0 123 280 1 1
BAK1 MTFR1 0 0 165 187 1 1
BAK1 AGK 0 0 0 229 1 1
BAK1 UVRAG 0 0 134 191 1 2
BAK1 MAPK1 0 0 145 170 1 2
BAK1 IGF1 0 0 173 173 1 2
BAK1 SERPINE1 0 0 55 162 1 1
BAK1 PPP2CA 0 0 140 251 1 1
BAK1 CDK1 0 0 286 312 1 2
BAK1 SCFD2 0 0 0 296 1 1
BAK1 CHMP4B 0 0 0 169 1 2
BAK1 EHD3 0 0 108 246 1 1
BAK1 BAD 0 0 517 613 1 2
BAK1 RPS6KB1 0 0 150 197 1 2
BAK1 UBL4A 0 0 0 153 1 1
BAK1 PLSCR2 0 0 178 177 1 1
BAK1 EFS 0 0 154 153 1 1
BAK1 ATP5F1 0 0 0 158 1 1
BAK1 MTIF3 0 0 0 314 1 1
BAK1 BCL2L2 694 540 564 878 1 1
BAK1 C8A 0 720 0 732 1 1
BAK1 FAU 0 0 0 180 1 2
BAK1 C14orf2 0 0 0 169 1 1
BAK1 MRPS33 0 0 86 230 1 1
BAK1 CCND1 0 0 315 335 1 2
BAK1 DNAJB2 0 0 113 168 1 1
BAK1 CAPN14 0 0 126 254 1 1
BAK1 DFFA 67 0 261 312 1 1
BAK1 MT-ND5 270 0 0 404 1 1
BAK1 LIN28A 0 0 233 232 1 1
BAK1 CARD18 0 0 81 233 1 1
BAK1 E2F8 0 0 0 223 1 1
BAK1 TP53I3 0 0 124 170 1 1
BAK1 MYB 0 0 162 180 1 1
BAK1 BCL2 756 900 503 979 1 2
BAK1 BCAT2 0 0 0 384 1 1
BAK1 ACOT8 0 0 0 187 1 1
BAK1 FDFT1 0 0 53 155 1 1
BAK1 DDIT4 0 0 122 158 1 2
BAK1 WDR66 0 0 211 265 1 1
BAK1 MCUR1 0 0 0 429 1 1
BAK1 POU5F1 0 0 184 203 1 2
BAK1 TMEM230 0 0 0 377 1 1
BAK1 CANX 0 0 91 208 1 2
BAK1 CCNE1 0 0 143 184 1 1
BAK1 HRK 0 0 517 517 1 1
BAK1 NDUFA13 0 0 57 315 1 1
BAK1 CYC1 0 0 96 251 1 1
BAK1 ELMO2 0 0 0 333 1 1
BAK1 CAT 0 0 218 218 1 2
BAK1 LIN28B 0 0 161 161 1 1
BAK1 ATP5H 0 0 0 183 1 1
BAK1 TCHP 0 0 201 201 1 1
BAK1 C16orf58 0 0 0 228 1 1
BAK1 TRAPPC6B 0 0 0 305 1 1
BAK1 HMOX1 0 0 123 174 1 2
BAK1 RGS19 0 0 124 215 1 2
BAK1 NT5C 0 0 81 255 1 1
BAK1 JAK1 0 0 70 228 1 2
BAK1 DMRT1 0 0 520 526 1 1
BAK1 H6PD 0 0 0 269 1 1
BAK1 EIF2S1 0 0 154 153 1 2
BAK1 VDAC1 462 720 412 909 1 2
BAK1 LYRM4 0 0 0 157 1 1
BAK1 OXSM 0 0 0 319 1 1
BAK1 TGFB1 0 0 195 241 1 2
BAK1 ARID3B 0 0 254 254 1 1
BAK1 KLF8 0 0 42 155 1 1
BAK1 BNIP3L 0 0 261 304 1 2
BAK1 PRKCD 0 0 146 177 1 2
BAK1 CDKN1B 0 0 261 261 1 2
BAK1 BET1L 0 0 181 284 1 1
BAK1 RIPK3 0 0 242 258 1 2
BAK1 ZFYVE1 0 0 0 167 1 2
BAK1 RB1 0 0 103 177 1 2
BAK1 VDAC3 0 540 96 600 1 1
BAK1 TMEM256 0 0 0 321 1 1
BAK1 FOXO3 0 0 234 246 1 2
BAK1 ETFDH 0 0 0 382 1 1
BAK1 CRIP2 0 0 57 185 1 1
BAK1 HSD17B8 0 0 0 236 1 1
BAK1 ATG4C 0 0 101 165 1 2
BAK1 DAP3 0 0 66 203 1 1
BAK1 SRC 0 0 125 156 1 2
BAK1 ATP5J2 0 0 63 511 1 1
BAK1 LYPLA2 0 0 90 342 1 1
BAK1 HARS2 0 0 0 204 1 1
BAK1 ATG3 0 0 194 209 1 2
BAK1 BIRC6 0 0 267 300 1 1
BAK1 BNIP1 0 0 232 310 1 2
BAK1 CDKN3 0 0 193 207 1 1
BAK1 TOMM40L 0 540 0 561 1 1
BAK1 TP53INP1 0 0 292 317 1 2
BAK1 ZNF180 0 0 96 313 1 1
BAK1 EIF2AK3 0 0 228 227 1 2
BAK1 BIRC5 0 0 322 349 1 2
BAK1 CLGN 0 0 0 163 1 1
BAK1 NDUFB3 0 0 0 236 1 1
BAK1 BCL6 0 0 141 154 1 1
BAK1 PINK1 0 0 103 241 1 2
BAK1 GSK3A 0 0 123 155 1 1
BAK1 NDUFB6 0 0 62 315 1 1
BAK1 TYMS 0 0 123 159 1 1
BAK1 EIF4EBP1 0 0 155 179 1 2
BAK1 RNF7 0 0 66 241 1 1
BAK1 ERI3 0 0 0 183 1 1
BAK1 BIRC8 0 0 241 271 1 1
BAK1 MTX2 0 0 0 273 1 1
BAK1 AKAP14 0 0 113 174 1 1
BAK1 HSP90AB1 0 0 103 192 1 2
BAK1 PDPR 0 0 0 284 1 1
BAK1 NDUFB10 0 0 0 152 1 1
BAK1 IMMP1L 0 0 182 218 1 1
BAK1 GOSR1 0 0 0 273 1 1
BAK1 GBAS 0 0 0 157 1 1
BAK1 MAP3K1 0 0 142 160 1 1
BAK1 PYCARD 0 0 202 247 1 2
BAK1 PRKRA 0 0 164 347 1 1
BAK1 AIFM1 0 0 259 336 1 1
BAK1 TNFSF8 0 0 213 267 1 1
BAK1 CARD6 0 0 210 241 1 1
BAK1 CCNE2 0 0 157 157 1 1
BAK1 BBC3 0 0 608 622 1 2
BAK1 NOP10 0 0 0 162 1 1
BAK1 C19orf10 0 0 0 186 1 1
BAK1 PPM1E 0 0 252 252 1 1
BAK1 CD34 0 720 131 746 1 2
BAK1 PRDX3 0 0 52 192 1 1
BAK1 HMGA2 0 0 108 166 1 1
BAK1 VTI1A 0 0 0 171 1 1
BAK1 PMF1-BGLAP 0 0 155 167 1 1
BAK1 ERBB2 0 0 288 303 1 2
BAK1 HERC1 273 0 74 298 1 1
BAK1 NDUFA5 0 0 0 185 1 1
BAK1 MKI67 0 0 124 161 1 2
BAK1 CD48 0 0 307 317 1 1
BAK1 VMA21 0 0 0 272 1 2
BAK1 UBE3A 270 0 81 345 1 1
BAK1 CCDC108 0 0 108 247 1 1
BAK1 AKT1 0 0 500 524 1 2
BAK1 CAPN1 0 800 181 848 1 2
BAK1 UQCRFS1 0 0 0 198 1 1
BAK1 CD4 0 0 155 164 1 2
BAK1 ATF4 0 0 161 195 1 2
BAK1 FAS 0 0 286 301 1 2
BAK1 CARD8 0 0 153 293 1 1
BAK1 KLF4 0 0 166 179 1 2
BAK1 DUOX1 0 0 0 196 1 1
BAK1 CARS2 0 0 0 159 1 1
BAK1 ATF6 0 0 182 182 1 2
BAK1 HUS1 0 0 107 204 1 1
BAK1 XIAP 0 0 390 414 1 2
BAK1 TMEM74 0 0 341 401 1 2
BAK1 SPRY4 0 0 595 604 1 1
BAK1 DROSHA 0 0 211 211 1 1
BAK1 SDHD 0 0 48 401 1 1
BAK1 KCNJ6 0 0 447 447 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0051400 Molecular Function BH domain binding enables IEA
GO:0031072 Molecular Function heat shock protein binding enables IEA
GO:0042802 Molecular Function identical protein binding enables IPI
GO:0046872 Molecular Function metal ion binding enables IEA
GO:0003674 Molecular Function molecular_function enables ND
GO:0015288 Molecular Function porin activity enables IDA
GO:0005515 Molecular Function protein binding enables IPI
GO:0046982 Molecular Function protein heterodimerization activity enables IBA
GO:0046982 Molecular Function protein heterodimerization activity enables IPI
GO:0042803 Molecular Function protein homodimerization activity enables IBA
GO:0042803 Molecular Function protein homodimerization activity enables IDA
GO:0044877 Molecular Function protein-containing complex binding enables IEA
GO:0051087 Molecular Function protein-folding chaperone binding enables IEA
GO:0044325 Molecular Function transmembrane transporter binding enables IPI
GO:0001783 Biological Process B cell apoptotic process involved_in IEA
GO:0001782 Biological Process B cell homeostasis involved_in IEA
GO:0002352 Biological Process B cell negative selection involved_in IEA
GO:0097202 Biological Process activation of cysteine-type endopeptidase activity involved_in IDA
GO:0031100 Biological Process animal organ regeneration involved_in IEA
GO:0006915 Biological Process apoptotic process involved_in IDA
GO:0006915 Biological Process apoptotic process involved_in NAS
GO:1902262 Biological Process apoptotic process involved in blood vessel morphogenesis involved_in IEA
GO:0097190 Biological Process apoptotic signaling pathway involved_in IMP
GO:0001974 Biological Process blood vessel remodeling involved_in IEA
GO:0060402 Biological Process calcium ion transport into cytosol involved_in IEA
GO:0034644 Biological Process cellular response to UV involved_in IMP
GO:0034644 Biological Process cellular response to UV involved_in ISS
GO:0071260 Biological Process cellular response to mechanical stimulus involved_in IEP
GO:0034620 Biological Process cellular response to unfolded protein involved_in TAS
GO:0031018 Biological Process endocrine pancreas development involved_in IEA
GO:0032469 Biological Process endoplasmic reticulum calcium ion homeostasis involved_in TAS
GO:0050673 Biological Process epithelial cell proliferation involved_in IEA
GO:0010248 Biological Process establishment or maintenance of transmembrane electrochemical gradient involved_in IDA
GO:0097192 Biological Process extrinsic apoptotic signaling pathway in absence of ligand involved_in IBA
GO:0044346 Biological Process fibroblast apoptotic process involved_in IEA
GO:0097193 Biological Process intrinsic apoptotic signaling pathway involved_in IDA
GO:0008630 Biological Process intrinsic apoptotic signaling pathway in response to DNA damage involved_in IBA
GO:0070059 Biological Process intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress involved_in TAS
GO:0035108 Biological Process limb morphogenesis involved_in IEA
GO:0008053 Biological Process mitochondrial fusion involved_in IEA
GO:0002262 Biological Process myeloid cell homeostasis involved_in IEA
GO:0008285 Biological Process negative regulation of cell population proliferation involved_in IEA
GO:0032471 Biological Process negative regulation of endoplasmic reticulum calcium ion concentration involved_in IEA
GO:0010629 Biological Process negative regulation of gene expression involved_in IEA
GO:1901029 Biological Process negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway involved_in IDA
GO:0033137 Biological Process negative regulation of peptidyl-serine phosphorylation involved_in IEA
GO:0090201 Biological Process negative regulation of release of cytochrome c from mitochondria involved_in IDA
GO:1903896 Biological Process positive regulation of IRE1-mediated unfolded protein response involved_in TAS
GO:0043065 Biological Process positive regulation of apoptotic process involved_in IMP
GO:0043065 Biological Process positive regulation of apoptotic process involved_in ISS
GO:0010524 Biological Process positive regulation of calcium ion transport into cytosol involved_in IEA
GO:1900103 Biological Process positive regulation of endoplasmic reticulum unfolded protein response involved_in IMP
GO:1901030 Biological Process positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway involved_in NAS
GO:0031334 Biological Process positive regulation of protein-containing complex assembly involved_in IDA
GO:0045862 Biological Process positive regulation of proteolysis involved_in IDA
GO:0090200 Biological Process positive regulation of release of cytochrome c from mitochondria involved_in NAS
GO:0048597 Biological Process post-embryonic camera-type eye morphogenesis involved_in IEA
GO:0051726 Biological Process regulation of cell cycle involved_in IEA
GO:0046902 Biological Process regulation of mitochondrial membrane permeability involved_in IDA
GO:0051881 Biological Process regulation of mitochondrial membrane potential involved_in IDA
GO:0001836 Biological Process release of cytochrome c from mitochondria involved_in IDA
GO:0001836 Biological Process release of cytochrome c from mitochondria involved_in IGI
GO:0010225 Biological Process response to UV-C involved_in IEA
GO:0045471 Biological Process response to ethanol involved_in IEA
GO:0009620 Biological Process response to fungus involved_in IEA
GO:0010332 Biological Process response to gamma radiation involved_in IEA
GO:0042542 Biological Process response to hydrogen peroxide involved_in IEA
GO:0010046 Biological Process response to mycotoxin involved_in IEA
GO:0014070 Biological Process response to organic cyclic compound involved_in IEA
GO:0009410 Biological Process response to xenobiotic stimulus involved_in IEA
GO:0070242 Biological Process thymocyte apoptotic process involved_in IEA
GO:0060068 Biological Process vagina development involved_in IEA
GO:0097145 Cellular Component BAK complex part_of IDA
GO:0097145 Cellular Component BAK complex part_of IPI
GO:0097136 Cellular Component Bcl-2 family protein complex part_of IDA
GO:0097136 Cellular Component Bcl-2 family protein complex part_of IPI
GO:0005829 Cellular Component cytosol located_in IEA
GO:0005783 Cellular Component endoplasmic reticulum located_in IEA
GO:0005741 Cellular Component mitochondrial outer membrane is_active_in IBA
GO:0005741 Cellular Component mitochondrial outer membrane is_active_in IDA
GO:0005741 Cellular Component mitochondrial outer membrane located_in IDA
GO:0005741 Cellular Component mitochondrial outer membrane located_in ISS
GO:0005741 Cellular Component mitochondrial outer membrane located_in TAS
GO:0005739 Cellular Component mitochondrion located_in IDA
GO:0046930 Cellular Component pore complex part_of IDA
Pathways
Name DB ID
Apoptosis Reactome R-HSA-109581
Intrinsic Pathway for Apoptosis Reactome R-HSA-109606
Activation and oligomerization of BAK protein Reactome R-HSA-111452
Release of apoptotic factors from the mitochondria Reactome R-HSA-111457
Apoptotic factor-mediated response Reactome R-HSA-111471
Regulated Necrosis Reactome R-HSA-5218859
Programmed Cell Death Reactome R-HSA-5357801
Pyroptosis Reactome R-HSA-5620971
DNA IR-double strand breaks and cellular response via ATM (WP3959) WikiPathways WP3959_r118468
Photodynamic therapy-induced HIF-1 survival signaling (WP3614) WikiPathways WP3614_r106542
Chromosomal and microsatellite instability in colorectal cancer (WP4216) WikiPathways WP4216_r123363
Measles virus infection (WP4630) WikiPathways WP4630_r123414
Nanomaterial induced apoptosis (WP2507) WikiPathways WP2507_r123897
Complement system in neuronal development and plasticity (WP5090) WikiPathways WP5090_r118898
Breast cancer pathway (WP4262) WikiPathways WP4262_r123349
Melanoma (WP4685) WikiPathways WP4685_r123437
Oxidative damage response (WP3941) WikiPathways WP3941_r123242
DNA damage response (only ATM dependent) (WP710) WikiPathways WP710_r116542
Regulation of apoptosis by parathyroid hormone-related protein (WP3872) WikiPathways WP3872_r123397
Small cell lung cancer (WP4658) WikiPathways WP4658_r124606
Apoptosis (WP254) WikiPathways WP254_r118382
Nonalcoholic fatty liver disease (WP4396) WikiPathways WP4396_r123350
Pancreatic adenocarcinoma pathway (WP4263) WikiPathways WP4263_r123405
Photodynamic therapy-induced AP-1 survival signaling (WP3611) WikiPathways WP3611_r120501
Apoptosis modulation and signaling (WP1772) WikiPathways WP1772_r120736
Non-small cell lung cancer (WP4255) WikiPathways WP4255_r123348
Regucalcin in proximal tubule epithelial kidney cells (WP4838) WikiPathways WP4838_r110282
Endometrial cancer (WP4155) WikiPathways WP4155_r123347
Malignant pleural mesothelioma (WP5087) WikiPathways WP5087_r122659
Transcripts
Accession Version MolecularType Name NCBI Comments
NM_001188 4 mRNA None NC_000006 Reference
XM_011514779 4 mRNA transcript variant X1 NC_000006 Reference
XM_011514780 2 mRNA transcript variant X3 NC_000006 Reference
XM_047419196 1 mRNA transcript variant X4 NC_000006 Reference
XM_047419194 1 mRNA transcript variant X2 NC_000006 Reference