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PVT1

Pvt1 oncogene
General Information
Name Pvt1 oncogene
Alias
  • CXCR4/PVT1 fusion
  • HIST1H2BD/PVT1 fusion
  • MIR1204, MIR1205, MIR1206 and MIR1207 host
  • Oncogene PVT-1 (MYC activator)
  • PVT1/CASC8 fusion
  • PVT1/CCDC26 fusion
  • PVT1/IFRD1 fusion
  • PVT1/IRF2BP2 fusion
  • PVT1/LINC00824 fusion
  • PVT1/MYC fusion
  • PVT1/NFIL3 fusion
  • PVT1/NSMCE2 fusion
  • PVT1/SPRY2 fusion
  • PVT1/UBB fusion
  • Pvt1 oncogene (non-protein coding)
  • RP11-89K10/PVT1 fusion
  • long intergenic non-protein coding RNA 79
  • plasmacytoma variant translocation 1
  • pvt-1 (murine) oncogene homolog, MYC activator
Gene_family Long non-coding RNAs with non-systematic symbols|MicroRNA non-coding host genes
organism Homo sapiens
entrez_id 5820
location 8q24.21
transcript_count 50
exon_count 34
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez This gene represents a long non-coding RNA locus that has been identified as a candidate oncogene. Increased copy number and overexpression of this gene are associated with many types of cancers including breast and ovarian cancers, acute myeloid leukemia and Hodgkin lymphoma. Allelic variants of this gene are also associated with end-stage renal disease attributed to type 1 diabetes. Consistent with its association with various types of cancer, transcription of this gene is regulated by the tumor suppressor p53 through a canonical p53-binding site, and it has been implicated in regulating levels of the proto-oncogene MYC to promote tumorigenesis. [provided by RefSeq, Sep 2015]
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
PVT1 BioGRID TRIM28 GeneID BioGRID Affinity Capture-RNA; Protein-RNA
PVT1 BioGRID HSP90B1 GeneID BioGRID Protein-RNA
PVT1 BioGRID NOP2 GeneID BioGRID Protein-RNA
PVT1 BioGRID POTEKP GeneID BioGRID Protein-RNA
PVT1 BioGRID RBM25 GeneID BioGRID Protein-RNA
PVT1 BioGRID SPOP GeneID BioGRID Affinity Capture-RNA; Protein-RNA
PVT1 BioGRID RPS16 GeneID BioGRID Protein-RNA
PVT1 BioGRID KRT9 GeneID BioGRID Protein-RNA
PVT1 BioGRID ERG GeneID BioGRID Protein-RNA
PVT1 BioGRID RUNX3 GeneID BioGRID Affinity Capture-RNA
PVT1 BioGRID HNRNPL GeneID BioGRID Affinity Capture-RNA
PVT1 BioGRID TRIM25 GeneID BioGRID Affinity Capture-RNA
StringDB
A B experiments database textmining combined score hadb nhadb
Ontologies
ID Category Term Effect Evidence PubMed
Pathways
Name DB ID
Transcripts
Accession Version MolecularType Name NCBI Comments
NR_186144 1 ncRNA transcript variant 26 NC_000008 Reference
NR_186151 1 ncRNA transcript variant 33 NC_000008 Reference
NR_186156 1 ncRNA transcript variant 38 NC_000008 Reference
NR_186146 1 ncRNA transcript variant 28 NC_000008 Reference
NR_186126 1 ncRNA transcript variant 8 NC_000008 Reference
NR_186120 1 ncRNA transcript variant 3 NC_000008 Reference
NR_186131 1 ncRNA transcript variant 13 NC_000008 Reference
NR_186168 1 ncRNA transcript variant 50 NC_000008 Reference
NR_186119 1 ncRNA transcript variant 2 NC_000008 Reference
NR_186137 1 ncRNA transcript variant 19 NC_000008 Reference
NR_186145 1 ncRNA transcript variant 27 NC_000008 Reference
NR_186158 1 ncRNA transcript variant 40 NC_000008 Reference
NR_186125 1 ncRNA transcript variant 7 NC_000008 Reference
NR_186121 1 ncRNA transcript variant 4 NC_000008 Reference
NR_186132 1 ncRNA transcript variant 14 NC_000008 Reference
NR_186123 1 ncRNA transcript variant 5 NC_000008 Reference
NR_186142 1 ncRNA transcript variant 24 NC_000008 Reference
NR_186129 1 ncRNA transcript variant 11 NC_000008 Reference
NR_186134 1 ncRNA transcript variant 16 NC_000008 Reference
NR_186141 1 ncRNA transcript variant 23 NC_000008 Reference
NR_186136 1 ncRNA transcript variant 18 NC_000008 Reference
NR_186148 1 ncRNA transcript variant 30 NC_000008 Reference
NR_186147 1 ncRNA transcript variant 29 NC_000008 Reference
NR_186164 1 ncRNA transcript variant 46 NC_000008 Reference
NR_186150 1 ncRNA transcript variant 32 NC_000008 Reference
NR_186161 1 ncRNA transcript variant 43 NC_000008 Reference
NR_186155 1 ncRNA transcript variant 37 NC_000008 Reference
NR_003367 4 ncRNA transcript variant 1 NC_000008 Reference
NR_186130 1 ncRNA transcript variant 12 NC_000008 Reference
NR_186149 1 ncRNA transcript variant 31 NC_000008 Reference
NR_186124 1 ncRNA transcript variant 6 NC_000008 Reference
NR_186127 1 ncRNA transcript variant 9 NC_000008 Reference
NR_186135 1 ncRNA transcript variant 17 NC_000008 Reference
NR_186140 1 ncRNA transcript variant 22 NC_000008 Reference
NR_186165 1 ncRNA transcript variant 47 NC_000008 Reference
NR_186133 1 ncRNA transcript variant 15 NC_000008 Reference
NR_186143 1 ncRNA transcript variant 25 NC_000008 Reference
NR_186128 1 ncRNA transcript variant 10 NC_000008 Reference
NR_186153 1 ncRNA transcript variant 35 NC_000008 Reference
NR_186154 1 ncRNA transcript variant 36 NC_000008 Reference
NR_186159 1 ncRNA transcript variant 41 NC_000008 Reference
NR_186167 1 ncRNA transcript variant 49 NC_000008 Reference
NR_186160 1 ncRNA transcript variant 42 NC_000008 Reference
NR_186152 1 ncRNA transcript variant 34 NC_000008 Reference
NR_186166 1 ncRNA transcript variant 48 NC_000008 Reference
NR_186162 1 ncRNA transcript variant 44 NC_000008 Reference
NR_186157 1 ncRNA transcript variant 39 NC_000008 Reference
NR_186163 1 ncRNA transcript variant 45 NC_000008 Reference
NR_186138 1 ncRNA transcript variant 20 NC_000008 Reference
NR_186139 1 ncRNA transcript variant 21 NC_000008 Reference