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RELB

RELB proto-oncogene, NF-kB subunit
General Information
Name RELB proto-oncogene, NF-kB subunit
Alias
  • transcription factor RelB
  • v-rel avian reticuloendotheliosis viral oncogene homolog B (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3)
  • v-rel reticuloendotheliosis viral oncogene homolog B, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3
Gene_family IPT domain containing|NF-kappa B complex subunits
organism Homo sapiens
entrez_id 5971
location 19q13.32
transcript_count 5
exon_count 14
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and protein kinase binding activity. Involved in lymphocyte differentiation and negative regulation of interferon-beta production. Located in cytosol and nucleoplasm. Part of chromatin; nucleus; and transcription repressor complex. Colocalizes with centrosome. Implicated in breast cancer and immunodeficiency 53. Biomarker of breast cancer and transitional cell carcinoma. [provided by Alliance of Genome Resources, Apr 2022]
    Stringdb Transcription factor RelB; NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF- kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguisha [...]
    nextProt NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors. NF-kappa-B complexes are held in the cytoplasm in an inactive state complexed with members of the NF-kappa-B inhibitor (I-kappa-B) family. In a conventional activation pathway, I-kappa-B is phosphorylated by I-kappa-B kinases (IKKs) in response to different activators, subsequently degraded thus liberating the active NF-kappa-B complex which translocates to the nucleus. NF-kappa-B heterodimeric RelB-p50 and RelB-p52 complexes are transcriptional activators. RELB neither associates with DNA nor with RELA/p65 or REL. Stimulates promoter activity in the presence of NFKB2/p49. As a member of the NUPR1/RELB/IER3 survival pathway, may provide pancreatic ductal adenocarcinoma with remarkable resistance to cell stress, such as starvation or gemcitabine treatment. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-BMAL1 heterodimer in a CRY1/CRY2 independent manner. Increased repression of the heterodimer is seen in the presence of NFKB2/p52. Is required for both T and B lymphocyte maturation and function (PubMed:26385063).
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
RELB BioGRID DAXX GeneID BioGRID Affinity Capture-Western
RELB BioGRID TOP3B GeneID BioGRID Affinity Capture-RNA
RELB BioGRID MAP1LC3A GeneID BioGRID Protein-peptide
RELB BioGRID EGFR GeneID BioGRID Negative Genetic
RELB BioGRID RELA GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-localization
RELB BioGRID NFKB2 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-localization
RELB BioGRID NFKB1 GeneID BioGRID Affinity Capture-MS; Proximity Label-MS; Two-hybrid
RELB BioGRID TAX1BP1 GeneID BioGRID Proximity Label-MS
RELB BioGRID CBL GeneID BioGRID Affinity Capture-Western
RELB BioGRID TNIP2 GeneID BioGRID Affinity Capture-MS
RELB BioGRID FBXW7 GeneID BioGRID Affinity Capture-MS
RELB BioGRID KLHL20 GeneID BioGRID Affinity Capture-MS
RELB BioGRID EEF1AKMT3 GeneID BioGRID Affinity Capture-MS
RELB BioGRID SMARCD3 GeneID BioGRID Affinity Capture-MS
RELB BioGRID SMARCD2 GeneID BioGRID Affinity Capture-MS
RELB BioGRID SMARCD1 GeneID BioGRID Affinity Capture-MS
RELB BioGRID SMARCC1 GeneID BioGRID Affinity Capture-MS
RELB BioGRID SMARCA2 GeneID BioGRID Affinity Capture-MS
RELB BioGRID REL GeneID BioGRID Affinity Capture-MS
RELB BioGRID NFKBIE GeneID BioGRID Affinity Capture-MS
RELB BioGRID NFKBIB GeneID BioGRID Affinity Capture-MS
RELB BioGRID NFKBIA GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
RELB BioGRID CTBS GeneID BioGRID Affinity Capture-MS
RELB BioGRID DDX39A GeneID BioGRID Affinity Capture-RNA
RELB BioGRID USP7 GeneID BioGRID Affinity Capture-Western
RELB BioGRID MALT1 GeneID BioGRID Biochemical Activity
RELB BioGRID HULC GeneID BioGRID Affinity Capture-MS
RELB BioGRID S1PR1 GeneID BioGRID Negative Genetic
RELB BioGRID ITFG1 GeneID BioGRID Affinity Capture-MS
RELB BioGRID MAP3K14 GeneID BioGRID Affinity Capture-MS
RELB BioGRID XPNPEP3 GeneID BioGRID Affinity Capture-MS
RELB BioGRID KPNA6 GeneID BioGRID Affinity Capture-MS
RELB BioGRID ZHX2 GeneID BioGRID Affinity Capture-Western
RELB BioGRID TCEAL1 GeneID BioGRID Affinity Capture-MS
RELB BioGRID USP11 GeneID BioGRID Affinity Capture-MS
RELB BioGRID PSMA4 GeneID BioGRID Affinity Capture-MS
RELB BioGRID PCMT1 GeneID BioGRID Affinity Capture-MS
RELB BioGRID SMAD4 GeneID BioGRID Affinity Capture-Western
RELB BioGRID SMAD3 GeneID BioGRID Affinity Capture-Western
RELB BioGRID SMAD2 GeneID BioGRID Affinity Capture-Western
RELB BioGRID KPNA2 GeneID BioGRID Affinity Capture-MS
RELB BioGRID KPNA1 GeneID BioGRID Affinity Capture-MS
RELB BioGRID STAT3 GeneID BioGRID Co-localization
RELB BioGRID SMARCC2 GeneID BioGRID Affinity Capture-MS
RELB BioGRID XPO1 GeneID BioGRID Affinity Capture-MS
RELB BioGRID BCL3 GeneID BioGRID Affinity Capture-Western; Co-localization
RELB BioGRID NEK6 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
RELB BioGRID MT1M GeneID BioGRID Two-hybrid
RELB BioGRID GSK3B GeneID BioGRID Affinity Capture-Western; Biochemical Activity
RELB BioGRID CTSL GeneID BioGRID Two-hybrid
RELB BioGRID CDK1 GeneID BioGRID Two-hybrid
RELB BioGRID BUD31 GeneID BioGRID Two-hybrid
RELB BioGRID UQCRFS1 GeneID BioGRID Two-hybrid
RELB BioGRID MTAP GeneID BioGRID Two-hybrid
RELB BioGRID COMMD9 GeneID BioGRID Affinity Capture-Western
RELB BioGRID COMMD5 GeneID BioGRID Affinity Capture-Western
RELB BioGRID COMMD1 GeneID BioGRID Affinity Capture-Western
RELB BioGRID COMMD8 GeneID BioGRID Affinity Capture-Western
RELB BioGRID COMMD4 GeneID BioGRID Affinity Capture-Western
RELB BioGRID COMMD10 GeneID BioGRID Affinity Capture-Western
RELB BioGRID COMMD2 GeneID BioGRID Affinity Capture-Western
RELB BioGRID RAC1 GeneID BioGRID Affinity Capture-Western
RELB BioGRID SUZ12 GeneID BioGRID Affinity Capture-Western
RELB BioGRID EZH2 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
RELB BioGRID DPF2 GeneID BioGRID Affinity Capture-MS; Reconstituted Complex
RELB BioGRID YY1 GeneID BioGRID Affinity Capture-Western
RELB BioGRID CBX3 GeneID BioGRID Co-localization
RELB BioGRID EHMT2 GeneID BioGRID Co-localization; Reconstituted Complex
RELB Protein KPNA6 GeneID HPRD
RELB Protein SMARCA4 GeneID HPRD
RELB Protein SMARCE1 GeneID HPRD
RELB Protein SMARCC2 GeneID HPRD
RELB Protein SMARCC1 GeneID HPRD
RELB Protein DPF2 GeneID HPRD
RELB Protein SMARCB1 GeneID HPRD
RELB Protein BCL7A GeneID HPRD
RELB Protein KPNA2 GeneID HPRD
RELB Protein HDAC6 GeneID HPRD
RELB Protein USP11 GeneID HPRD
RELB Protein RELA GeneID HPRD
RELB Protein NFKB2 GeneID HPRD
RELB Protein NFKB1 GeneID HPRD
RELB BioGRID HDAC6 GeneID BioGRID Affinity Capture-MS
RELB BioGRID SMARCE1 GeneID BioGRID Affinity Capture-MS
RELB BioGRID SMARCB1 GeneID BioGRID Affinity Capture-MS
RELB BioGRID SMARCA4 GeneID BioGRID Affinity Capture-MS
RELB BioGRID BCL7A GeneID BioGRID Affinity Capture-MS
RELB BioGRID ACTL6A GeneID BioGRID Affinity Capture-MS
StringDB
A B experiments database textmining combined score hadb nhadb
RELB IFIH1 0 0 300 359 1 1
RELB HBZ 0 0 170 176 1 1
RELB DIABLO 0 0 380 380 1 2
RELB HIST2H3PS2 0 0 588 588 1 1
RELB BATF3 0 0 403 437 1 1
RELB KLF5 0 0 126 201 1 2
RELB IL1F10 0 0 0 266 1 1
RELB MMP16 0 0 0 179 1 1
RELB TNS1 0 0 81 150 1 1
RELB CISH 0 0 217 245 1 1
RELB PTGER4 0 0 113 189 1 1
RELB NR3C1 0 0 218 218 1 1
RELB IL2RG 0 0 166 214 1 1
RELB SMARCB1 114 0 54 271 1 1
RELB CCR1 0 0 133 164 1 1
RELB ZNF148 0 0 55 156 1 1
RELB FLVCR2 0 0 75 187 1 1
RELB MAPK8 0 0 370 370 1 2
RELB ARG1 0 0 170 169 1 2
RELB SKP2 0 0 235 235 1 2
RELB IGHV4-38-2 0 0 243 242 1 1
RELB SHANK2 0 0 0 159 1 1
RELB PHLDA1 0 0 89 151 1 1
RELB GIF 0 0 164 169 1 1
RELB MAP2K4 0 0 170 169 1 1
RELB DPF2 404 0 655 785 1 1
RELB CD79B 0 0 233 260 1 1
RELB GADD45B 0 0 283 337 1 1
RELB CYCS 0 0 267 267 1 2
RELB MAPK9 0 0 217 217 1 2
RELB CXCL11 0 0 180 201 1 1
RELB ZNF219 0 0 95 296 1 1
RELB TLR7 0 0 341 341 1 2
RELB CASP9 0 0 269 269 1 2
RELB KLF13 0 0 113 249 1 1
RELB RPS6KA4 0 0 76 158 1 1
RELB NANOG 0 0 139 277 1 2
RELB TRAF6 0 0 609 630 1 2
RELB PELI1 0 0 195 195 1 1
RELB ETS1 0 0 265 290 1 1
RELB PLAU 0 0 181 211 1 1
RELB IL17A 0 0 452 452 1 2
RELB SMARCA5 0 0 48 152 1 1
RELB EGF 0 0 294 294 1 2
RELB CX3CR1 0 0 181 181 1 1
RELB NRARP 0 0 0 174 1 1
RELB IL12RB2 0 900 112 909 1 1
RELB PLAUR 0 0 113 185 1 1
RELB HSPA4 0 0 181 181 1 1
RELB IRF2 0 0 407 407 1 1
RELB ETV5 0 0 96 167 1 1
RELB SMARCA2 477 0 0 477 1 1
RELB XCR1 0 0 203 203 1 1
RELB CYP1B1 0 0 184 183 1 1
RELB PPARA 0 0 184 183 1 2
RELB IER3 0 0 287 344 1 1
RELB IL12B 0 900 0 900 1 1
RELB CXCL9 0 0 218 257 1 1
RELB CEBPD 0 0 267 302 1 1
RELB ISG20 0 0 95 152 1 1
RELB CCR2 0 0 218 218 1 2
RELB BPTF 0 0 0 303 1 1
RELB CD68 0 0 193 223 1 2
RELB CASP8 0 0 425 451 1 2
RELB ALB 0 0 301 349 1 2
RELB RC3H1 0 0 297 297 1 1
RELB CCL2 0 0 504 532 1 2
RELB SNAI2 0 0 187 187 1 1
RELB CD276 0 0 263 269 1 1
RELB IFI6 0 0 210 210 1 1
RELB IDO1 0 0 325 325 1 1
RELB TYROBP 0 0 142 184 1 1
RELB COMMD1 270 0 233 416 1 1
RELB KIAA0101 0 0 397 397 1 1
RELB IL17RE 0 0 0 224 1 1
RELB CASP7 0 0 194 212 1 1
RELB CUL1 0 600 216 672 1 1
RELB ITGB1 0 0 151 152 1 1
RELB IL9 0 0 217 217 1 1
RELB IL4 0 0 457 457 1 1
RELB NOTCH3 0 0 190 190 1 1
RELB EP300 0 0 391 394 1 2
RELB SIRPA 0 0 266 266 1 1
RELB LEF1 0 0 180 179 1 1
RELB IFI44L 0 0 214 214 1 1
RELB TNFRSF10A 0 0 241 270 1 1
RELB BIRC3 0 0 562 656 1 1
RELB IL17F 0 0 134 188 1 1
RELB SMAD3 270 0 245 425 1 2
RELB CDK6 0 0 195 200 1 2
RELB DUSP8 0 0 122 154 1 1
RELB FKBP4 0 0 457 457 1 1
RELB DDX58 0 0 370 394 1 1
RELB SIRT6 0 0 211 249 1 2
RELB MAPKAPK2 0 0 125 189 1 1
RELB GLI2 0 0 92 287 1 2
RELB RNF19B 0 0 83 174 1 1
RELB AGER 0 0 123 155 1 2
RELB DUSP10 0 0 123 153 1 1
RELB PRKCZ 0 0 134 156 1 1
RELB IDH1 0 0 392 392 1 1
RELB MFGE8 0 0 357 357 1 1
RELB PDPN 0 0 123 177 1 1
RELB CDH1 0 0 269 269 1 2
RELB ZEB2 0 0 170 169 1 1
RELB KLF12 0 0 90 247 1 1
RELB NFIL3 0 0 218 255 1 1
RELB MAF 0 0 283 298 1 1
RELB LGALS4 0 0 108 199 1 1
RELB RNF31 0 0 325 358 1 1
RELB SUZ12 270 0 135 341 1 1
RELB TRADD 0 0 505 552 1 1
RELB ATP8B2 0 0 49 173 1 1
RELB MAVS 0 0 258 258 1 2
RELB IL1A 0 0 421 456 1 1
RELB GBP1 0 0 203 266 1 1
RELB CCL4 0 0 284 344 1 1
RELB RHOB 0 0 90 301 1 1
RELB MLKL 0 0 171 189 1 2
RELB BCL10 0 0 600 614 1 1
RELB ESR2 0 0 439 473 1 1
RELB COMMD2 270 0 0 270 1 1
RELB CD160 0 0 398 398 1 1
RELB PTPRC 0 0 391 406 1 1
RELB ZBTB7B 0 0 92 317 1 1
RELB CD24 0 0 240 239 1 2
RELB ZEB1 0 0 172 171 1 2
RELB SIRT7 0 0 157 175 1 2
RELB ICAM1 0 0 469 566 1 2
RELB UNC93B1 0 0 60 195 1 1
RELB TNFRSF14 0 0 292 348 1 1
RELB CDKN1A 0 0 274 308 1 2
RELB NKRF 0 0 160 159 1 1
RELB SPP1 0 0 151 150 1 2
RELB CSF2RA 0 0 148 212 1 1
RELB NKX2-6 0 0 53 262 1 1
RELB ABTB1 0 0 0 171 1 1
RELB RHOA 0 0 150 220 1 2
RELB PARP1 0 0 193 208 1 2
RELB AR 0 0 261 261 1 2
RELB IFNAR2 0 0 136 168 1 1
RELB EPCAM 0 0 189 189 1 2
RELB CD1C 0 0 250 286 1 1
RELB TLR5 0 0 302 302 1 1
RELB CXCL12 0 0 323 323 1 2
RELB TIMP1 0 0 150 199 1 1
RELB UBE2N 0 0 323 323 1 1
RELB IL36A 0 0 72 290 1 1
RELB GABPB1 0 0 44 275 1 1
RELB GPR29 0 0 203 203 1 1
RELB ACTB 0 0 519 544 1 2
RELB SELP 0 0 141 162 1 1
RELB INS 0 0 282 282 1 2
RELB STUB1 0 0 207 207 1 2
RELB DNMT1 270 0 447 579 1 2
RELB CD40 0 0 987 988 1 2
RELB SELL 0 0 245 271 1 1
RELB CD8B 0 0 164 163 1 1
RELB SIRT3 0 0 202 202 1 2
RELB MAPK3 0 0 323 323 1 2
RELB DPF1 0 0 122 159 1 1
RELB PAX5 0 0 245 244 1 1
RELB KEAP1 0 0 201 220 1 2
RELB B2M 0 0 179 216 1 1
RELB MMP9 0 0 421 471 1 2
RELB FCGR2B 0 0 170 190 1 1
RELB SQSTM1 0 0 134 176 1 2
RELB JUNB 0 0 392 464 1 1
RELB GLI3 0 0 139 236 1 1
RELB HSP90AA1 0 0 327 327 1 2
RELB IL3 0 0 207 207 1 1
RELB LTB 0 0 556 734 1 1
RELB FOSL1 0 0 391 426 1 1
RELB BCL3 273 540 342 944 1 1
RELB FBXW7 0 0 432 432 1 2
RELB HPGDS 0 0 291 291 1 1
RELB ANKRD2 0 0 58 155 1 1
RELB ANKHD1-EIF4EBP3 0 0 0 163 1 1
RELB HDAC4 0 0 955 955 1 2
RELB CEBPA 0 0 287 304 1 1
RELB IFIT5 0 0 216 216 1 1
RELB SYT1 0 0 456 456 1 1
RELB PATZ1 0 0 0 211 1 1
RELB NKX2-4 0 0 51 261 1 1
RELB SOX2 0 0 154 153 1 2
RELB CRP 0 0 171 172 1 2
RELB ENSG00000173366 0 0 365 365 1 1
RELB MAPK12 0 0 143 201 1 1
RELB BCL2L11 0 0 321 321 1 2
RELB SERPINB2 0 0 134 179 1 1
RELB KPNA6 146 0 56 159 1 1
RELB IL10RA 0 0 167 225 1 1
RELB TYK2 0 900 211 919 1 1
RELB ZNF202 0 0 53 154 1 1
RELB TNIP3 0 0 269 312 1 1
RELB MAFB 0 0 181 198 1 1
RELB JUN 0 0 556 567 1 2
RELB TAPBP 0 0 124 325 1 1
RELB BATF 0 0 242 293 1 1
RELB ARID5A 0 0 74 186 1 1
RELB CASP1 0 0 298 354 1 2
RELB TK1 0 0 0 204 1 1
RELB CCNA2 0 0 210 210 1 1
RELB CHEK1 0 0 142 161 1 2
RELB DNTT 0 0 160 159 1 1
RELB GTF2H4 0 0 120 234 1 1
RELB CD74 0 0 167 209 1 1
RELB CD27 0 0 252 279 1 1
RELB PI4K2B 0 0 46 169 1 1
RELB JAK3 0 0 212 229 1 1
RELB MAP2K3 0 0 181 240 1 1
RELB TNFSF10 0 0 289 305 1 2
RELB ZFP36 0 0 150 195 1 1
RELB HSPA1A 103 0 97 165 1 1
RELB CD8A 0 0 459 459 1 1
RELB ADAM8 0 0 0 165 1 1
RELB BIK 0 0 142 167 1 2
RELB PSMB8 0 0 171 275 1 1
RELB ZBTB7A 0 0 67 273 1 1
RELB LSP1 0 0 112 155 1 1
RELB COMMD5 270 0 0 270 1 1
RELB SS18 0 0 0 189 1 1
RELB RUNX3 0 0 194 224 1 1
RELB MMP2 0 0 250 257 1 2
RELB IRF6 0 0 123 151 1 1
RELB TCIRG1 0 0 55 164 1 1
RELB NCOA3 0 0 135 158 1 1
RELB SLAMF1 0 0 134 176 1 1
RELB TNFRSF13C 0 0 717 717 1 1
RELB TNFSF4 0 0 275 275 1 1
RELB TNFRSF8 0 0 414 429 1 1
RELB NFATC3 0 0 166 165 1 1
RELB RIPK2 0 0 213 245 1 2
RELB ETV1 0 0 45 210 1 1
RELB HIVEP3 0 0 76 175 1 1
RELB LCK 0 0 250 250 1 1
RELB JAG1 0 0 233 232 1 1
RELB CLEC6A 0 0 233 272 1 1
RELB IL17RA 0 0 143 162 1 1
RELB CCRL2 0 0 208 269 1 1
RELB CTSF 0 0 0 161 1 1
RELB TICAM1 0 0 235 370 1 2
RELB NFKBIE 674 0 793 954 1 1
RELB PVRL2 0 0 134 188 1 1
RELB NKX2-2 0 0 67 202 1 1
RELB ANK1 0 0 74 169 1 1
RELB FYN 0 0 159 158 1 1
RELB IFI27L1 0 0 290 290 1 1
RELB DCSTAMP 0 0 170 169 1 1
RELB IL37 0 0 0 264 1 1
RELB ANKHD1 0 0 0 163 1 1
RELB CCR5 0 0 171 208 1 1
RELB IL36RN 0 0 43 266 1 1
RELB ARNT 0 0 398 399 1 2
RELB IL7R 0 0 212 233 1 1
RELB LTA 0 0 397 490 1 1
RELB KPNA2 130 0 60 165 1 1
RELB MIB2 0 0 70 186 1 1
RELB CD69 0 0 261 289 1 1
RELB CREBBP 0 0 292 340 1 1
RELB IGJ 0 0 212 212 1 1
RELB SDHB 0 0 231 230 1 1
RELB UBE2D3 0 0 156 155 1 1
RELB HCAR2 0 0 108 165 1 1
RELB CREB1 0 0 392 405 1 2
RELB TGFB3 0 0 118 212 1 1
RELB CCL5 0 0 401 449 1 2
RELB PLCG2 0 0 210 227 1 1
RELB TNFRSF17 0 0 173 173 1 1
RELB IL2RB 0 0 140 250 1 1
RELB IFNG 0 0 272 379 1 2
RELB BIRC2 0 0 609 634 1 1
RELB FBXO32 0 0 90 248 1 2
RELB RPS3 0 0 211 211 1 1
RELB LGALS9 0 0 88 199 1 1
RELB COMMD9 270 0 0 270 1 1
RELB CCNB1 0 0 171 171 1 1
RELB ANXA5 0 0 386 401 1 2
RELB CXCL13 0 0 396 396 1 1
RELB PLEC 0 0 0 161 1 1
RELB TNFSF9 0 0 193 216 1 1
RELB TNFSF18 0 0 181 181 1 1
RELB IL4R 0 0 167 286 1 1
RELB SIRT2 0 0 170 169 1 2
RELB KLF3 0 0 107 244 1 1
RELB STAT4 0 0 166 261 1 1
RELB CASP6 0 0 137 177 1 1
RELB TAB3 0 0 323 323 1 1
RELB ZAP70 0 0 248 257 1 1
RELB CLEC7A 0 0 321 325 1 1
RELB TLR10 0 0 215 331 1 1
RELB CALCR 0 0 156 173 1 1
RELB CLNK 0 0 52 150 1 1
RELB ELF5 0 0 0 167 1 1
RELB KITLG 0 0 166 165 1 1
RELB TUBB4A 106 0 113 173 1 1
RELB CCL4L1 0 0 155 174 1 1
RELB AOC3 0 0 204 204 1 1
RELB BCL2L1 0 0 556 575 1 2
RELB RELA 871 800 990 979 1 2
RELB HMGB2 0 0 0 152 1 1
RELB DNMT3A 0 0 154 153 1 2
RELB NFKB1 786 900 983 999 1 2
RELB KLF6 0 0 243 269 1 1
RELB DUSP5 0 0 170 210 1 1
RELB GAPDH 0 0 507 515 1 2
RELB TNFRSF25 0 0 167 167 1 1
RELB SIX2 270 0 0 270 1 1
RELB EGR3 0 0 193 193 1 1
RELB CYP1A1 0 0 286 286 1 2
RELB GEMIN7 0 0 127 214 1 1
RELB SMAD2 270 0 233 416 1 2
RELB TLR4 0 0 557 578 1 2
RELB MAP2K7 0 0 260 260 1 1
RELB NOS2 0 0 241 257 1 2
RELB CD1A 0 0 182 191 1 1
RELB CX3CL1 0 0 194 194 1 1
RELB NMI 0 0 102 167 1 1
RELB JAG2 0 0 165 196 1 1
RELB OAS2 0 0 142 174 1 1
RELB RPS6KA5 0 0 246 245 1 1
RELB CD83 0 0 326 376 1 1
RELB IL1B 0 0 613 650 1 2
RELB SP1 0 0 211 211 1 2
RELB TRAF5 0 0 460 471 1 1
RELB SIRT5 0 0 166 165 1 1
RELB HIF1A 0 0 372 372 1 2
RELB EDN1 0 0 138 161 1 1
RELB OAS1 0 0 204 223 1 1
RELB PRKCB 0 0 229 228 1 2
RELB BAG3 0 0 61 204 1 2
RELB IL6R 0 0 202 216 1 1
RELB NFKBID 0 0 808 840 1 1
RELB CTSL 111 0 125 204 1 2
RELB CXCL8 0 0 595 656 1 2
RELB MAPK13 0 0 123 191 1 1
RELB SELENBP1 0 0 0 187 1 1
RELB IGLL1 0 0 216 216 1 1
RELB GABPA 0 0 58 159 1 1
RELB RNF11 0 0 161 161 1 1
RELB EGR1 0 0 295 306 1 2
RELB CDK2 0 0 213 213 1 2
RELB HRAS 0 0 284 297 1 2
RELB FCGR3A 0 0 181 181 1 1
RELB CTNNB1 0 0 363 363 1 2
RELB XPO1 0 0 161 161 1 1
RELB IKBKE 0 0 342 471 1 1
RELB B7RP1 0 0 166 184 1 1
RELB TNFRSF1B 0 0 506 535 1 1
RELB CXCR2 0 0 175 175 1 1
RELB PTGS1 0 0 170 214 1 1
RELB CD40LG 0 0 561 566 1 1
RELB MMP1 0 0 180 204 1 1
RELB NOTCH1 0 0 393 415 1 2
RELB CXCR4 0 0 293 293 1 2
RELB PIDD1 0 0 263 339 1 1
RELB TRAF4 0 0 282 291 1 1
RELB SAA1 0 0 155 162 1 1
RELB KPNA1 146 0 445 506 1 1
RELB E2F2 0 0 142 175 1 1
RELB POTEF 0 0 168 211 1 1
RELB KLF7 0 0 96 260 1 1
RELB MTOR 0 0 261 261 1 2
RELB IL6 0 0 612 648 1 2
RELB CTRL 0 0 183 183 1 2
RELB IL3RA 0 0 146 184 1 1
RELB ETS2 0 0 181 255 1 1
RELB BTLA 0 0 384 396 1 1
RELB PLEK 0 0 134 183 1 1
RELB E2F6 0 0 122 381 1 1
RELB GZMB 0 0 152 183 1 1
RELB RILPL2 0 0 73 160 1 1
RELB TNFRSF1A 0 0 602 614 1 1
RELB TRIM37 0 0 53 153 1 1
RELB STAT1 0 0 464 486 1 2
RELB CBX3 273 0 0 273 1 1
RELB KPNA4 0 0 139 269 1 1
RELB IL20RA 0 0 46 293 1 1
RELB COMMD8 270 0 0 270 1 1
RELB IRF9 0 0 309 334 1 1
RELB MDM2 0 0 270 270 1 2
RELB TP53 0 0 615 615 1 2
RELB TNFRSF4 0 0 334 373 1 1
RELB MYD88 0 0 502 531 1 2
RELB EGFR 0 0 325 325 1 2
RELB CFLAR 0 0 468 468 1 2
RELB CDK4 0 0 228 227 1 2
RELB TSLP 0 0 219 219 1 1
RELB FADD 0 0 364 379 1 2
RELB TRAF1 0 0 560 637 1 1
RELB CARD9 0 0 320 360 1 1
RELB LMNA 0 0 212 267 1 2
RELB IRAK1 0 0 500 517 1 1
RELB CSF3 0 0 247 264 1 1
RELB NCOR2 0 0 209 209 1 1
RELB TNFRSF11B 0 0 211 211 1 1
RELB ASPH 0 0 0 207 1 1
RELB NFKBIZ 0 0 558 637 1 1
RELB TNS3 0 0 0 167 1 1
RELB DDIT3 0 0 183 183 1 2
RELB MAP3K7 0 0 406 406 1 2
RELB KPNA3 0 0 107 168 1 1
RELB HDAC2 0 0 230 229 1 1
RELB BOD1L1 0 0 45 170 1 1
RELB SNX22 0 0 95 189 1 1
RELB CDH2 0 0 143 161 1 1
RELB MKNK1 0 0 60 154 1 1
RELB HDAC6 114 0 143 208 1 2
RELB APAF1 0 0 182 181 1 2
RELB JAK2 0 900 268 925 1 2
RELB NLRC5 0 0 142 192 1 1
RELB PLA2G4C 0 0 118 151 1 1
RELB KLF10 0 0 123 236 1 1
RELB NR4A1 0 0 196 213 1 2
RELB CLU 0 0 74 189 1 2
RELB MAFF 0 0 123 188 1 1
RELB CTSW 0 0 0 161 1 1
RELB BRD4 0 0 150 172 1 2
RELB GATA3 0 0 261 261 1 1
RELB MMP15 0 0 0 179 1 1
RELB AATF 0 0 45 260 1 1
RELB NCOA1 0 0 97 161 1 1
RELB HBEGF 0 0 120 290 1 1
RELB EZH2 270 0 764 820 1 2
RELB IDO2 0 0 233 232 1 1
RELB GABPB2 0 0 70 295 1 1
RELB PPP1R12C 0 0 0 171 1 1
RELB STAT3 273 0 534 658 1 2
RELB IL18 0 0 325 336 1 2
RELB ILK 0 0 60 157 1 1
RELB IFNA1 0 0 335 335 1 1
RELB IL15 0 0 288 288 1 1
RELB PPRC1 0 0 134 157 1 1
RELB MYC 0 0 469 480 1 2
RELB ITGAE 0 0 292 292 1 1
RELB IL1R1 0 0 423 433 1 1
RELB H1F0 0 0 425 425 1 1
RELB HIST1H2BD 0 0 47 194 1 1
RELB TREM1 0 0 113 235 1 1
RELB SDHC 0 0 298 298 1 1
RELB TAB2 0 0 455 455 1 2
RELB IL36G 0 0 47 270 1 1
RELB CD300A 0 0 70 193 1 1
RELB MX1 0 0 251 298 1 1
RELB TRAF2 0 0 465 497 1 2
RELB TAB1 0 0 379 379 1 1
RELB ACP5 0 0 219 276 1 1
RELB MMP17 0 0 0 179 1 1
RELB IL2RA 0 0 218 231 1 1
RELB PIK3CA 0 0 164 163 1 2
RELB IL27RA 0 0 90 195 1 1
RELB SBNO2 0 0 0 165 1 1
RELB HDAC5 0 0 82 558 1 1
RELB CTSE 0 0 52 236 1 1
RELB CLEC4A 0 0 132 308 1 1
RELB MYCN 0 0 108 306 1 1
RELB SMAD4 270 0 441 574 1 2
RELB TNFRSF12A 0 0 391 418 1 1
RELB SHANK1 0 0 0 193 1 1
RELB LY75 0 0 261 292 1 1
RELB TAX1BP1 0 0 287 286 1 2
RELB CHI3L1 0 0 249 248 1 1
RELB TNFRSF13B 0 0 294 294 1 1
RELB CASP10 0 0 112 152 1 1
RELB IL12A 0 900 0 905 1 1
RELB NUPR1 0 0 188 205 1 2
RELB IL17RC 0 0 102 158 1 1
RELB AKT2 0 0 163 163 1 2
RELB TLR1 0 0 324 391 1 1
RELB EHMT2 270 0 872 902 1 2
RELB NFE2L2 0 0 170 169 1 2
RELB BCL7A 114 0 0 267 1 1
RELB PSMB3 0 0 53 267 1 1
RELB CDKN2D 0 0 91 224 1 1
RELB CARD10 0 0 293 308 1 1
RELB MAP3K8 0 0 375 423 1 1
RELB MAP2K1 0 0 233 232 1 1
RELB DHX58 0 0 159 245 1 1
RELB OSM 0 0 108 152 1 1
RELB TCF3 0 0 171 171 1 1
RELB OASL 0 0 242 299 1 1
RELB RBCK1 0 0 371 386 1 1
RELB CD80 0 0 426 446 1 2
RELB BRCA1 0 0 202 202 1 2
RELB CCL21 0 0 370 377 1 1
RELB NFKBIB 0 0 793 824 1 1
RELB ALPK3 0 0 45 170 1 1
RELB SLC15A3 0 0 57 172 1 1
RELB CD1E 0 0 182 201 1 1
RELB ISG15 0 0 170 221 1 2
RELB UBC 0 900 73 903 1 2
RELB SERPINB5 0 0 123 177 1 1
RELB HSPB1 0 0 134 165 1 2
RELB GLI1 0 0 101 191 1 2
RELB VAV1 0 0 160 179 1 1
RELB IL22RA1 0 0 113 235 1 1
RELB PMPCB 0 0 0 642 1 1
RELB CXCR5 0 0 193 217 1 1
RELB MMP13 0 0 170 177 1 2
RELB NEURL3 0 0 97 217 1 1
RELB PILRA 0 0 120 199 1 1
RELB TBP 0 0 203 203 1 1
RELB FN1 0 0 262 262 1 2
RELB CCR9 0 0 158 157 1 1
RELB CCR7 0 0 381 417 1 1
RELB IKBKG 0 0 801 812 1 1
RELB RAG2 0 0 181 181 1 1
RELB RARA 0 0 108 161 1 2
RELB TBX21 0 0 268 294 1 1
RELB RIPK4 0 0 102 194 1 1
RELB KLF16 0 0 109 177 1 1
RELB PLK3 0 0 95 199 1 1
RELB RPS6KA1 0 0 181 221 1 1
RELB DST 0 0 0 228 1 2
RELB LYN 0 0 204 222 1 1
RELB CTSK 0 0 194 228 1 2
RELB IFNB1 0 0 459 459 1 1
RELB IRF5 0 0 294 341 1 1
RELB RAC1 270 0 74 300 1 2
RELB HMGB1 0 0 207 323 1 2
RELB PIM2 0 0 217 217 1 1
RELB C11orf57 0 0 95 151 1 1
RELB ESR1 0 0 368 368 1 2
RELB ACKR2 0 0 171 171 1 1
RELB OPTN 0 0 174 224 1 2
RELB MAP3K5 0 0 208 208 1 1
RELB PDCD1 0 0 134 179 1 2
RELB ITGAM 0 0 393 416 1 1
RELB SMARCD2 458 0 60 513 1 1
RELB PDK4 0 0 383 383 1 1
RELB TUBB 105 0 90 150 1 1
RELB SMAD7 0 0 202 236 1 1
RELB TLE3 0 0 177 177 1 1
RELB ELF4 0 0 0 243 1 1
RELB SMARCA4 243 0 172 346 1 1
RELB SIRT1 0 0 813 813 1 2
RELB AIRE 0 0 537 537 1 1
RELB MCL1 0 0 335 351 1 2
RELB NKX2-3 0 0 112 207 1 2
RELB SPI1 0 0 456 486 1 1
RELB LMNB1 0 0 210 211 1 1
RELB CST7 0 0 81 153 1 1
RELB IER2 0 0 105 179 1 1
RELB HLA-C 0 0 88 166 1 1
RELB IRF1 0 0 509 562 1 2
RELB TNFAIP2 0 0 267 401 1 1
RELB SP3 0 0 155 154 1 1
RELB CXCR3 0 0 160 400 1 1
RELB STAT2 0 0 325 325 1 1
RELB ZNF281 0 0 48 172 1 1
RELB COMMD4 270 0 0 270 1 1
RELB XBP1 0 0 195 195 1 2
RELB NT5DC4 0 0 0 199 1 1
RELB TLR8 0 0 261 282 1 1
RELB EDAR 0 0 180 179 1 1
RELB MAP2K6 0 0 170 169 1 1
RELB KLF11 0 0 85 288 1 1
RELB ARGFX 0 0 58 226 1 1
RELB NFATC1 0 0 373 428 1 2
RELB PDCD1LG2 0 0 147 196 1 1
RELB CASP5 0 0 115 178 1 1
RELB TRAF7 0 0 315 324 1 1
RELB MYOD1 0 0 137 156 1 1
RELB STX11 0 0 0 175 1 1
RELB PTEN 0 0 322 321 1 2
RELB ARID2 0 0 185 193 1 1
RELB VEGFA 0 0 391 390 1 2
RELB IRF4 0 0 504 517 1 1
RELB MAPK7 0 0 155 189 1 1
RELB TNFRSF11A 0 0 322 321 1 1
RELB BST2 0 0 142 167 1 1
RELB E2F3 0 0 141 183 1 1
RELB UBA52 0 900 0 900 1 1
RELB CD79A 0 0 209 256 1 1
RELB SREBF1 0 0 103 164 1 1
RELB CNTN2 0 0 203 219 1 1
RELB TNFRSF9 0 0 261 277 1 1
RELB RORC 0 0 169 180 1 1
RELB CLEC4E 0 0 167 326 1 1
RELB MAPK14 0 0 213 288 1 2
RELB KIT 0 0 228 227 1 2
RELB NFKBIA 762 540 972 997 1 2
RELB UBE2M 0 900 49 900 1 1
RELB SYK 0 0 341 355 1 2
RELB S1PR1 189 0 123 263 1 1
RELB TCF4 0 0 205 205 1 1
RELB ZC3H12A 0 0 381 540 1 1
RELB NKAP 0 0 170 239 1 1
RELB MAP3K3 0 0 204 222 1 1
RELB FCGR3B 0 0 170 169 1 1
RELB CCL22 0 0 266 282 1 1
RELB CCL3 0 0 334 377 1 1
RELB THBD 0 0 160 185 1 1
RELB ATM 0 0 286 286 1 2
RELB TNFRSF10C 0 0 141 190 1 1
RELB CTSD 0 0 57 152 1 2
RELB AXIN1 0 0 107 155 1 1
RELB IL23A 0 0 219 265 1 1
RELB FLT3 0 0 249 248 1 2
RELB CXCL2 0 0 371 429 1 1
RELB RBPJ 0 0 325 325 1 1
RELB IRAK4 0 0 364 364 1 1
RELB GFAP 0 0 142 161 1 2
RELB PSMB10 0 0 150 213 1 1
RELB ZHX2 270 0 0 270 1 1
RELB SNAI1 0 0 240 262 1 1
RELB IL10 0 0 505 505 1 2
RELB CCL20 0 0 372 432 1 1
RELB IKZF1 0 0 241 258 1 1
RELB FOSL2 0 0 401 422 1 1
RELB ANKRD31 0 0 81 221 1 1
RELB PSMB11 0 0 186 204 1 1
RELB ACTG1 102 0 161 230 1 1
RELB HIVEP2 0 0 123 217 1 1
RELB SELE 0 0 297 301 1 1
RELB TGFBR2 0 0 113 232 1 1
RELB FOSB 0 0 345 345 1 1
RELB SMARCC2 469 0 72 532 1 1
RELB IFIT1B 0 0 284 284 1 1
RELB CEBPB 0 0 412 465 1 2
RELB IL13RA1 0 0 119 207 1 1
RELB PIK3CD 0 0 134 159 1 1
RELB KIDINS220 0 0 0 157 1 1
RELB NOD2 0 0 289 334 1 2
RELB CIITA 0 0 252 268 1 1
RELB PRDM1 0 0 288 306 1 1
RELB HDAC1 0 0 491 491 1 2
RELB CSF1 0 0 336 383 1 1
RELB RIPK1 0 0 459 477 1 2
RELB LTBR 0 0 708 753 1 1
RELB ITGAX 0 0 392 405 1 1
RELB GSK3B 270 0 142 392 1 2
RELB MRC1 0 0 194 199 1 1
RELB CDKN2A 0 0 270 345 1 2
RELB CASP4 0 0 202 273 1 2
RELB CXCL16 0 0 136 158 1 1
RELB RPS27A 117 900 57 909 1 1
RELB EPHB2 0 0 57 202 1 2
RELB CUL3 0 0 123 151 1 2
RELB CHUK 164 900 979 998 1 1
RELB KLF2 0 0 187 220 1 1
RELB PIGR 0 0 157 157 1 1
RELB TONSL 0 0 487 539 1 1
RELB PRKCQ 0 0 179 215 1 2
RELB CD1B 0 0 188 239 1 1
RELB TNFRSF10B 0 0 267 300 1 2
RELB IL13 0 0 315 315 1 2
RELB CTSS 0 0 90 158 1 1
RELB USP11 146 0 435 496 1 2
RELB NOTCH2 0 0 280 280 1 1
RELB ETV7 0 0 47 298 1 1
RELB TNFSF13B 0 0 731 732 1 1
RELB ALOX5 0 0 134 160 1 1
RELB SMARCA1 0 0 0 183 1 1
RELB CXCL5 0 0 194 248 1 1
RELB CD5 0 0 212 231 1 1
RELB CD28 0 0 373 373 1 1
RELB CYBB 0 0 180 207 1 2
RELB NLRP3 0 0 219 234 1 2
RELB REL 876 540 990 952 1 2
RELB MMP14 0 0 81 241 1 1
RELB IL33 0 0 181 181 1 2
RELB CTSZ 0 0 0 158 1 1
RELB CXCL1 0 0 381 459 1 2
RELB UBE2V1 0 0 218 218 1 1
RELB GFPT1 0 0 90 159 1 1
RELB AICDA 0 0 173 173 1 1
RELB CCL11 0 0 161 179 1 1
RELB PTGS2 0 0 493 522 1 2
RELB PSMB9 0 0 184 220 1 1
RELB CASP3 0 0 452 452 1 2
RELB DAXX 486 0 319 643 1 1
RELB TNFRSF21 0 0 137 155 1 1
RELB ENSG00000277117 0 0 166 184 1 1
RELB CD86 0 0 425 458 1 1
RELB IL18R1 0 0 108 316 1 1
RELB CARD11 0 0 549 565 1 1
RELB NOD1 0 0 216 251 1 2
RELB MADCAM1 0 0 283 282 1 1
RELB SHARPIN 0 0 324 340 1 1
RELB ZNF300 0 0 47 194 1 1
RELB TLR6 0 0 258 356 1 1
RELB IL2 0 0 454 454 1 1
RELB SMARCD3 477 0 0 488 1 1
RELB SDC1 0 0 180 179 1 1
RELB OTUD7B 0 0 242 257 1 1
RELB CCL7 0 0 171 213 1 1
RELB TRAF3 0 0 681 715 1 2
RELB ERF 0 0 0 226 1 1
RELB CDKN2C 0 0 73 168 1 1
RELB TOLLIP 0 0 205 206 1 1
RELB TLR2 0 0 457 518 1 2
RELB CDKN2B 0 0 125 238 1 1
RELB IFITM5 0 0 228 229 1 1
RELB PMAIP1 0 0 241 240 1 2
RELB MAPK11 0 0 119 161 1 1
RELB DUSP1 0 0 232 231 1 1
RELB BTRC 0 900 372 934 1 1
RELB FTH1 0 0 113 163 1 1
RELB E2F1 0 0 141 174 1 2
RELB HSPA5 102 0 113 169 1 2
RELB ITFG1 270 0 0 270 1 1
RELB NKX3-2 0 0 103 230 1 1
RELB IFNGR1 0 0 134 173 1 1
RELB CCL17 0 0 235 245 1 1
RELB HLA-B 0 0 96 189 1 1
RELB CD3E 0 0 155 155 1 1
RELB SOD2 0 0 322 367 1 2
RELB FOXO1 0 0 245 244 1 2
RELB KRAS 0 0 245 292 1 2
RELB LILRB4 0 0 135 153 1 1
RELB ITGB2 0 0 91 202 1 1
RELB ASB2 0 0 0 161 1 1
RELB IGSF6 0 0 120 191 1 1
RELB PTK6 0 0 0 207 1 2
RELB IL15RA 0 0 167 263 1 1
RELB CLEC9A 0 0 215 226 1 1
RELB SOCS3 0 0 261 305 1 1
RELB TWIST1 0 0 181 181 1 1
RELB BSX 0 0 0 150 1 1
RELB KDM6B 0 0 151 176 1 1
RELB FASLG 0 0 289 288 1 1
RELB FOS 0 0 469 469 1 2
RELB SIGIRR 0 0 123 167 1 1
RELB IRAK3 0 0 323 337 1 1
RELB TNIP1 0 0 263 401 1 1
RELB PTPN11 0 0 164 163 1 1
RELB TNIP2 484 0 309 663 1 1
RELB BIRC7 0 0 135 172 1 1
RELB MMP24 0 0 0 179 1 1
RELB STAT5A 0 0 375 412 1 1
RELB NKPD1 0 0 136 302 1 1
RELB HSP90AB1 0 0 60 157 1 2
RELB FOXO4 0 0 142 158 1 1
RELB PDLIM2 0 0 255 271 1 1
RELB GP2 0 0 163 163 1 1
RELB CXCL10 0 0 390 453 1 2
RELB MALT1 270 0 606 700 1 1
RELB RHOC 0 0 90 168 1 1
RELB CYLD 0 0 560 560 1 1
RELB PHGDH 0 0 260 260 1 1
RELB ID2 0 0 325 325 1 1
RELB ZBTB46 0 0 242 241 1 1
RELB SIRT4 0 0 182 181 1 1
RELB BIRC5 0 0 141 166 1 2
RELB BCL6 0 0 334 384 1 1
RELB CTSO 0 0 46 446 1 1
RELB IRF3 0 0 464 468 1 2
RELB CR2 0 0 234 238 1 1
RELB NKX2-8 0 0 0 214 1 1
RELB ERBB2 0 0 260 260 1 2
RELB NGF 0 0 165 165 1 2
RELB WDR81 0 0 60 208 1 1
RELB CD34 0 0 244 243 1 2
RELB BBC3 0 0 173 245 1 2
RELB AIFM1 0 0 0 201 1 1
RELB MAP3K1 0 0 340 340 1 1
RELB PYCARD 0 0 143 174 1 2
RELB ANKRA2 0 0 0 157 1 1
RELB MAFK 0 0 76 170 1 1
RELB CD1D 0 0 249 266 1 1
RELB TNFSF8 0 0 389 411 1 1
RELB TLR9 0 0 390 390 1 2
RELB GFPT2 0 0 62 205 1 1
RELB GRK5 0 0 123 217 1 1
RELB FAS 0 0 235 270 1 2
RELB SUMO1 0 0 143 158 1 1
RELB CARD14 0 0 210 210 1 1
RELB IFIT3 0 0 136 157 1 1
RELB VCAM1 0 0 414 417 1 1
RELB INPP5D 0 0 150 167 1 1
RELB CD4 0 0 517 532 1 2
RELB PPARG 0 0 315 330 1 2
RELB PPP1R13L 0 0 107 215 1 1
RELB IL17RB 0 0 125 208 1 1
RELB SPIB 0 0 404 404 1 1
RELB AKT1 0 0 548 556 1 2
RELB GBP2 0 0 81 163 1 1
RELB LY96 0 0 234 277 1 1
RELB CSF2 0 0 460 474 1 1
RELB IL12RB1 0 900 140 910 1 1
RELB IFNLR1 0 0 0 173 1 1
RELB CLEC4C 0 0 148 153 1 1
RELB E2F4 0 0 170 217 1 1
RELB RUNX2 0 0 175 175 1 2
RELB PPP2R4 0 0 154 153 1 1
RELB CEBPG 0 0 182 217 1 1
RELB XIAP 0 0 460 476 1 2
RELB NEURL1B 0 0 150 168 1 1
RELB KLF4 0 0 203 222 1 2
RELB MSS51 0 0 46 171 1 1
RELB APOL3 0 0 92 154 1 1
RELB IKBKB 0 0 803 826 1 2
RELB NLRC4 0 0 145 169 1 2
RELB UBA3 0 900 0 900 1 1
RELB NKX3-1 0 0 95 235 1 1
RELB ELK4 0 0 69 168 1 1
RELB PIAS4 0 0 193 193 1 1
RELB YY1 270 0 893 919 1 1
RELB RAC2 0 0 115 200 1 1
RELB NFATC2 0 0 315 340 1 1
RELB JAK1 0 0 253 252 1 2
RELB IL4I1 0 0 48 255 1 1
RELB SKP1 0 600 218 673 1 2
RELB COMMD3 270 0 0 270 1 1
RELB IL32 0 0 145 186 1 1
RELB FOXP3 0 0 423 434 1 2
RELB HMOX1 0 0 241 286 1 2
RELB CD82 0 0 72 152 1 1
RELB TCHP 0 0 203 203 1 1
RELB TBK1 0 0 391 411 1 2
RELB TICAM2 0 0 164 184 1 1
RELB RIPK3 0 0 243 287 1 2
RELB IFIT1 0 0 212 212 1 1
RELB MMP10 0 0 162 169 1 1
RELB PARP10 0 0 0 153 1 1
RELB CDKN1B 0 0 181 181 1 2
RELB PRKCD 0 0 185 241 1 2
RELB USP7 114 0 139 204 1 1
RELB LEUTX 0 0 57 158 1 1
RELB KLF8 0 0 91 273 1 1
RELB IKZF2 0 0 112 155 1 1
RELB CDRT4 0 0 122 154 1 1
RELB TGFB1 0 0 113 257 1 2
RELB STAT5B 0 0 342 342 1 1
RELB ACTL6A 118 0 0 156 1 1
RELB IRF8 0 0 464 498 1 1
RELB SRC 0 0 323 347 1 2
RELB SMARCC1 102 0 57 197 1 1
RELB APOC1 0 0 74 216 1 1
RELB CDC42 0 0 156 162 1 2
RELB RAG1 0 0 207 207 1 1
RELB TNFSF11 0 0 519 530 1 2
RELB CD47 0 0 92 153 1 2
RELB COMMD10 270 0 235 418 1 1
RELB CREB5 0 0 122 273 1 1
RELB IL36B 0 0 0 265 1 1
RELB FOXO3 0 0 260 260 1 2
RELB APOE 0 0 166 165 1 2
RELB ALYREF 0 0 305 305 1 1
RELB MARCKSL1 0 0 102 179 1 1
RELB HNF4A 0 0 159 158 1 1
RELB EIF2AK3 0 0 235 235 1 2
RELB TP53INP1 0 0 83 176 1 2
RELB TNFSF12 0 0 417 434 1 1
RELB TCF12 0 0 150 173 1 1
RELB STAT6 0 0 322 347 1 1
RELB LGALS3 0 0 69 251 1 2
RELB JDP2 0 0 142 213 1 1
RELB TLR3 0 0 416 416 1 2
RELB ANKRD17 0 0 0 258 1 1
RELB TNFRSF18 0 0 261 287 1 1
RELB FBXW11 0 600 0 600 1 1
RELB CADM1 0 0 157 156 1 1
RELB KLF1 0 0 107 231 1 1
RELB ERC1 0 0 217 217 1 1
RELB CD207 0 0 218 222 1 1
RELB EGR2 0 0 213 258 1 1
RELB LOX 0 0 155 154 1 2
RELB MMP19 0 0 53 451 1 1
RELB SGK1 0 0 81 209 1 2
RELB KAT2B 0 0 181 181 1 1
RELB HEY1 0 0 170 169 1 1
RELB RPS6KB1 0 0 170 188 1 2
RELB HIVEP1 0 0 91 292 1 1
RELB TNFAIP8 0 0 120 199 1 1
RELB ETV6 0 0 51 272 1 1
RELB SERPINE1 0 0 164 182 1 1
RELB AHR 0 0 988 989 1 2
RELB PRKDC 129 0 60 169 1 2
RELB NCOR1 0 0 171 171 1 1
RELB CDK1 111 0 157 218 1 2
RELB CD274 0 0 244 312 1 2
RELB SREBF2 0 0 89 151 1 1
RELB CSF2RB 0 0 90 162 1 1
RELB TNFRSF10D 0 0 122 153 1 1
RELB CCND1 0 0 469 483 1 2
RELB ARHGEF7 0 0 700 704 1 1
RELB JUND 0 0 406 419 1 1
RELB NOS3 0 0 166 165 1 2
RELB FLT3LG 0 0 255 254 1 1
RELB BLNK 0 0 181 182 1 1
RELB IRAK2 0 0 391 426 1 1
RELB NCF1 0 0 108 155 1 1
RELB PSIP1 0 0 201 201 1 1
RELB IFIT2 0 0 159 190 1 1
RELB CD19 0 0 302 322 1 1
RELB HPRT1 0 0 193 193 1 1
RELB RNASEL 0 0 74 169 1 1
RELB IFI44 0 0 228 256 1 1
RELB CD38 0 0 150 168 1 2
RELB SMAD6 0 0 113 270 1 1
RELB MYB 0 0 163 163 1 1
RELB BAK1 0 0 138 198 1 2
RELB COLEC12 0 0 0 424 1 1
RELB LIN28A 0 0 181 181 1 1
RELB CCL19 0 0 417 438 1 1
RELB TP53I3 0 0 108 191 1 1
RELB KLF9 0 0 89 183 1 1
RELB CTLA4 0 0 391 390 1 2
RELB ETV2 0 0 47 327 1 1
RELB UBB 0 900 0 900 1 1
RELB GFI1 0 0 181 210 1 1
RELB CAT 0 0 205 205 1 2
RELB PECAM1 0 0 161 161 1 1
RELB TAL1 0 0 113 154 1 1
RELB NEK6 270 0 0 270 1 1
RELB NT5C2 0 0 0 303 1 1
RELB LCP1 0 0 0 275 1 1
RELB TXN 0 0 181 181 1 1
RELB CCNE1 0 0 94 150 1 1
RELB BDNF 0 0 146 165 1 2
RELB SIN3A 213 0 74 240 1 1
RELB CD44 0 0 340 364 1 2
RELB MMP25 0 0 0 209 1 1
RELB ESRP2 0 0 0 208 1 1
RELB IL7 0 0 242 259 1 1
RELB MMP3 0 0 181 191 1 1
RELB IL1RN 0 0 203 273 1 1
RELB VDR 0 0 193 229 1 2
RELB NR4A2 0 0 145 183 1 1
RELB IFITM1 0 0 203 203 1 1
RELB SMARCD1 459 0 0 480 1 1
RELB TANK 0 0 340 340 1 2
RELB TNF 0 0 720 779 1 2
RELB UQCRC1 0 0 0 357 1 1
RELB TIRAP 0 0 265 281 1 1
RELB HLA-DMA 0 0 136 187 1 1
RELB NFAT5 0 0 127 189 1 1
RELB PPP1R15A 0 0 96 150 1 2
RELB TPX2 0 0 54 647 1 1
RELB ETV3 0 0 86 289 1 1
RELB IFI30 0 0 233 323 1 1
RELB IFI27 0 0 181 181 1 1
RELB MMP7 0 0 134 188 1 1
RELB CD209 0 0 181 222 1 1
RELB DRAM1 0 0 67 152 1 2
RELB CXCL3 0 0 273 347 1 1
RELB GCSAM 0 0 63 153 1 1
RELB FGF2 0 0 180 179 1 2
RELB TYMP 0 0 0 169 1 1
RELB TNFSF14 0 0 386 386 1 1
RELB IFI16 0 0 193 222 1 1
RELB BCL2A1 0 0 366 434 1 1
RELB IFNAR1 0 0 182 197 1 1
RELB CCND2 0 0 181 181 1 1
RELB ENSG00000272980 0 0 203 203 1 1
RELB IL1R2 0 0 157 198 1 1
RELB CD70 0 0 213 235 1 1
RELB MAP3K14 70 900 563 958 1 1
RELB IL5 0 0 262 262 1 1
RELB TNFAIP3 0 0 556 668 1 2
RELB SPN 0 0 160 161 1 1
RELB NFKB2 973 900 990 999 1 1
RELB CSF1R 0 0 260 341 1 1
RELB IGF1 0 0 210 210 1 2
RELB MAPK1 0 0 171 171 1 2
RELB IRF7 0 0 427 486 1 1
RELB BTK 0 0 323 347 1 1
RELB RFXANK 0 0 0 157 1 1
RELB SOCS1 0 0 277 329 1 1
RELB ARNTL 0 0 828 828 1 1
RELB IFI35 0 0 247 285 1 1
RELB GADD45A 0 0 211 228 1 1
RELB CLASRP 0 0 0 294 1 1
RELB RELT 0 0 101 193 1 1
RELB ATF3 0 0 323 356 1 2
RELB CD3EAP 0 0 49 193 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0000981 Molecular Function DNA-binding transcription factor activity, RNA polymerase II-specific enables IBA
GO:0000981 Molecular Function DNA-binding transcription factor activity, RNA polymerase II-specific enables ISA
GO:0000978 Molecular Function RNA polymerase II cis-regulatory region sequence-specific DNA binding enables IBA
GO:0000978 Molecular Function RNA polymerase II cis-regulatory region sequence-specific DNA binding enables IDA
GO:0000978 Molecular Function RNA polymerase II cis-regulatory region sequence-specific DNA binding enables ISS
GO:0042802 Molecular Function identical protein binding enables IEA
GO:0005515 Molecular Function protein binding enables IPI
GO:0019901 Molecular Function protein kinase binding enables IPI
GO:0045063 Biological Process T-helper 1 cell differentiation involved_in IEA
GO:0019882 Biological Process antigen processing and presentation involved_in IEA
GO:0007249 Biological Process canonical NF-kappaB signal transduction involved_in IBA
GO:0071470 Biological Process cellular response to osmotic stress involved_in IEA
GO:0033554 Biological Process cellular response to stress involved_in IBA
GO:0032922 Biological Process circadian regulation of gene expression involved_in ISS
GO:0006954 Biological Process inflammatory response involved_in IBA
GO:0045087 Biological Process innate immune response involved_in IBA
GO:0030098 Biological Process lymphocyte differentiation involved_in IMP
GO:0043011 Biological Process myeloid dendritic cell differentiation involved_in IEA
GO:0045892 Biological Process negative regulation of DNA-templated transcription involved_in IEA
GO:0032688 Biological Process negative regulation of interferon-beta production involved_in IMP
GO:0038061 Biological Process non-canonical NF-kappaB signal transduction involved_in IBA
GO:0045944 Biological Process positive regulation of transcription by RNA polymerase II involved_in IBA
GO:0045944 Biological Process positive regulation of transcription by RNA polymerase II involved_in NAS
GO:0034097 Biological Process response to cytokine involved_in IBA
GO:0071159 Cellular Component NF-kappaB complex part_of NAS
GO:0005813 Cellular Component centrosome colocalizes_with IDA
GO:0000785 Cellular Component chromatin part_of IDA
GO:0000785 Cellular Component chromatin part_of ISA
GO:0005829 Cellular Component cytosol located_in IDA
GO:0005829 Cellular Component cytosol located_in TAS
GO:0005654 Cellular Component nucleoplasm located_in IDA
GO:0005654 Cellular Component nucleoplasm located_in TAS
GO:0005634 Cellular Component nucleus located_in IDA
GO:0032991 Cellular Component protein-containing complex part_of IDA
GO:0045202 Cellular Component synapse located_in IEA
GO:0017053 Cellular Component transcription repressor complex part_of IDA
Pathways
Name DB ID
Cytokine Signaling in Immune system Reactome R-HSA-1280215
Innate Immune System Reactome R-HSA-168249
Immune System Reactome R-HSA-168256
Dectin-1 mediated noncanonical NF-kB signaling Reactome R-HSA-5607761
CLEC7A (Dectin-1) signaling Reactome R-HSA-5607764
C-type lectin receptors (CLRs) Reactome R-HSA-5621481
CD209 (DC-SIGN) signaling Reactome R-HSA-5621575
TNFR2 non-canonical NF-kB pathway Reactome R-HSA-5668541
NIK-->noncanonical NF-kB signaling Reactome R-HSA-5676590
Toll-like receptor signaling related to MyD88 (WP3858) WikiPathways WP3858_r117850
EDA signaling in hair follicle development (WP3930) WikiPathways WP3930_r116431
miRNAs involvement in the immune response in sepsis (WP4329) WikiPathways WP4329_r123505
MAPK signaling pathway (WP382) WikiPathways WP382_r119087
Circadian rhythm genes (WP3594) WikiPathways WP3594_r117682
NRP1-triggered signaling pathways in pancreatic cancer (WP5144) WikiPathways WP5144_r120537
Thymic stromal lymphopoietin (TSLP) signaling pathway (WP2203) WikiPathways WP2203_r120724
TNF-related weak inducer of apoptosis (TWEAK) signaling pathway (WP2036) WikiPathways WP2036_r120940
RANKL/RANK signaling pathway (WP2018) WikiPathways WP2018_r120672
Neovascularisation processes (WP4331) WikiPathways WP4331_r107654
Non-genomic actions of 1,25 dihydroxyvitamin D3 (WP4341) WikiPathways WP4341_r122900
Photodynamic therapy-induced NF-kB survival signaling (WP3617) WikiPathways WP3617_r106541
LDL- influence on CD14 and TLR4 (WP5272) WikiPathways WP5272_r123542
Ebola virus infection in host (WP4217) WikiPathways WP4217_r120623
Transcripts
Accession Version MolecularType Name NCBI Comments
XM_047439189 1 mRNA transcript variant X2 NC_000019 Reference
NM_006509 4 mRNA transcript variant 1 NC_000019 Reference
XM_005259128 3 mRNA transcript variant X1 NC_000019 Reference
NM_001411087 1 mRNA transcript variant 2 NC_000019 Reference
XM_047439190 1 mRNA transcript variant X3 NC_000019 Reference