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REST

RE1 silencing transcription factor
General Information
Name RE1 silencing transcription factor
Alias
  • RE1-silencing transcription factor
  • neural-restrictive silencer factor
  • neuron restrictive silencer factor
  • repressor binding to the X2 box
Gene_family
organism Homo sapiens
entrez_id 5978
location 4q12
transcript_count 5
exon_count 5
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez This gene was initially identified as a transcriptional repressor that represses neuronal genes in non-neuronal tissues. However, depending on the cellular context, this gene can act as either an oncogene or a tumor suppressor. The encoded protein is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regulator of neurogenesis. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2018]
    Stringdb RE1-silencing transcription factor; Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. Transcriptional repression by REST-C [...]
    nextProt Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells (PubMed:12399542, PubMed:26551668, PubMed:7697725, PubMed:7871435, PubMed:8568247, PubMed:11741002, PubMed:11779185). Restricts the expression of neuronal genes by associating with two distinct corepressors, SIN3A and RCOR1, which in turn recruit histone deacetylase to the promoters of REST-regulated genes (PubMed:10449787, PubMed:10734093). Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier (By similarity). Transcriptional repression by REST-CDYL via the recruitment of histone methyltransferase EHMT2 may be important in transformation suppression (PubMed:19061646). Represses the expression of SRRM4 in non-neural cells to prevent the activation of neural-specific splicing events and to prevent production of REST isoform 3 (By similarity). Repressor activity may be inhibited by forming heterodimers with isoform 3, thereby preventing binding to NRSE or binding to corepressors and leading to derepression of target genes (PubMed:11779185). Also maintains repression of neuronal genes in neural stem cells, and allows transcription and differentiation into neurons by dissociation from RE1/NRSE sites of target genes (By similarity). Thereby is involved in maintaining the quiescent state of adult neural stem cells and preventing premature differentiation into mature neurons (PubMed:21258371). Plays a role in the developmental switch in synaptic NMDA receptor composition during postnatal development, by repressing GRIN2B expression and thereby altering NMDA receptor properties from containing primarily GRIN2B to primarily GRIN2A subunits (By similarity). Acts as a regulator of osteoblast differentiation (By similarity). Key repressor of gene expression in hypoxia; represses genes in hypoxia by direct binding to an RE1/NRSE site on their promoter regions (PubMed:27531581). May also function in stress resistance in the brain during aging; possibly by regulating expression of genes involved in cell death and in the stress response (PubMed:24670762). Repressor of gene expression in the hippocampus after ischemia by directly binding to RE1/NRSE sites and recruiting SIN3A and RCOR1 to promoters of target genes, thereby promoting changes in chromatin modifications and ischemia-induced cell death (By similarity). After ischemia, might play a role in repression of miR-132 expression in hippocampal neurons, thereby leading to neuronal cell death (By similarity). Negatively regulates the expression of SRRM3 in breast cancer cell lines (PubMed:26053433).
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
REST BioGRID LATS1 GeneID BioGRID Affinity Capture-MS
REST BioGRID MDM2 GeneID BioGRID Affinity Capture-Western
REST BioGRID DVL2 GeneID BioGRID Affinity Capture-MS
REST BioGRID CUL4B GeneID BioGRID Affinity Capture-Western; Co-localization
REST BioGRID CELSR3 GeneID BioGRID Reconstituted Complex
REST BioGRID BTRC GeneID BioGRID Affinity Capture-Western
REST BioGRID TP53 GeneID BioGRID Affinity Capture-MS
REST BioGRID FASN GeneID BioGRID Negative Genetic
REST BioGRID H2BC21 GeneID BioGRID Proximity Label-MS
REST BioGRID H2BC5 GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
REST BioGRID H4C1 GeneID BioGRID Affinity Capture-MS
REST BioGRID APEX1 GeneID BioGRID Affinity Capture-RNA
REST BioGRID AGRN GeneID BioGRID Affinity Capture-MS
REST BioGRID VIRMA GeneID BioGRID Affinity Capture-RNA
REST BioGRID H1-2 GeneID BioGRID Affinity Capture-MS
REST BioGRID H1-0 GeneID BioGRID Affinity Capture-MS
REST BioGRID FHL1 GeneID BioGRID Affinity Capture-MS
REST BioGRID FAU GeneID BioGRID Affinity Capture-MS
REST BioGRID EWSR1 GeneID BioGRID Affinity Capture-MS
REST BioGRID FBL GeneID BioGRID Affinity Capture-MS
REST BioGRID ELAVL1 GeneID BioGRID Affinity Capture-MS
REST BioGRID EIF2S1 GeneID BioGRID Affinity Capture-MS
REST BioGRID DMD GeneID BioGRID Affinity Capture-MS
REST BioGRID DHX9 GeneID BioGRID Affinity Capture-MS
REST BioGRID DDX3X GeneID BioGRID Affinity Capture-MS
REST BioGRID COL12A1 GeneID BioGRID Affinity Capture-MS
REST BioGRID CAT GeneID BioGRID Affinity Capture-MS
REST BioGRID C1QBP GeneID BioGRID Affinity Capture-MS
REST BioGRID BRAF GeneID BioGRID Affinity Capture-MS
REST BioGRID ATP5F1B GeneID BioGRID Affinity Capture-MS
REST BioGRID RERE GeneID BioGRID Affinity Capture-MS
REST BioGRID SLC25A5 GeneID BioGRID Affinity Capture-MS
REST BioGRID PARP1 GeneID BioGRID Affinity Capture-Western; Co-localization
REST BioGRID SEC23IP GeneID BioGRID Affinity Capture-MS
REST BioGRID ADAMTS6 GeneID BioGRID Affinity Capture-MS
REST BioGRID PSIP1 GeneID BioGRID Affinity Capture-MS
REST BioGRID SF3B2 GeneID BioGRID Affinity Capture-MS
REST BioGRID HNRNPA0 GeneID BioGRID Affinity Capture-MS
REST BioGRID RUVBL2 GeneID BioGRID Affinity Capture-MS
REST BioGRID IGF2BP1 GeneID BioGRID Affinity Capture-MS
REST BioGRID SPAG5 GeneID BioGRID Affinity Capture-MS
REST BioGRID CHERP GeneID BioGRID Affinity Capture-MS
REST BioGRID DDX17 GeneID BioGRID Affinity Capture-MS
REST BioGRID SYNCRIP GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-localization
REST BioGRID TUBB4B GeneID BioGRID Affinity Capture-MS
REST BioGRID HNRNPR GeneID BioGRID Affinity Capture-MS
REST BioGRID ALYREF GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-localization
REST BioGRID TRIM28 GeneID BioGRID Affinity Capture-Western; Co-localization
REST BioGRID HDAC5 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-localization
REST BioGRID NR1D2 GeneID BioGRID Affinity Capture-MS
REST BioGRID G3BP2 GeneID BioGRID Affinity Capture-MS
REST BioGRID MATR3 GeneID BioGRID Affinity Capture-MS
REST BioGRID MACROH2A1 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPL23 GeneID BioGRID Affinity Capture-MS
REST BioGRID DDX21 GeneID BioGRID Affinity Capture-MS
REST BioGRID MTMR4 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPL14 GeneID BioGRID Affinity Capture-MS
REST BioGRID H1-10 GeneID BioGRID Affinity Capture-MS
REST BioGRID H2BC11 GeneID BioGRID Affinity Capture-MS
REST BioGRID SYNJ1 GeneID BioGRID Affinity Capture-MS
REST BioGRID SRSF9 GeneID BioGRID Affinity Capture-MS
REST BioGRID SMARCA5 GeneID BioGRID Affinity Capture-MS
REST BioGRID H2BC9 GeneID BioGRID Affinity Capture-MS
REST BioGRID H2BC15 GeneID BioGRID Affinity Capture-MS
REST BioGRID H2AC6 GeneID BioGRID Affinity Capture-MS
REST BioGRID H2AC14 GeneID BioGRID Affinity Capture-MS
REST BioGRID SF3A2 GeneID BioGRID Affinity Capture-MS
REST BioGRID TAF15 GeneID BioGRID Affinity Capture-MS
REST BioGRID TUFM GeneID BioGRID Affinity Capture-MS
REST BioGRID SSBP1 GeneID BioGRID Affinity Capture-MS
REST BioGRID SRP14 GeneID BioGRID Affinity Capture-MS
REST BioGRID SNRPN GeneID BioGRID Affinity Capture-MS
REST BioGRID SNRPE GeneID BioGRID Affinity Capture-MS
REST BioGRID SNRPD3 GeneID BioGRID Affinity Capture-MS
REST BioGRID SNRPD1 GeneID BioGRID Affinity Capture-MS
REST BioGRID SNRPA1 GeneID BioGRID Affinity Capture-MS
REST BioGRID SRSF7 GeneID BioGRID Affinity Capture-MS
REST BioGRID SRSF6 GeneID BioGRID Affinity Capture-MS
REST BioGRID SRSF5 GeneID BioGRID Affinity Capture-MS
REST BioGRID SRSF3 GeneID BioGRID Affinity Capture-MS
REST BioGRID SRSF1 GeneID BioGRID Affinity Capture-MS
REST BioGRID SFPQ GeneID BioGRID Affinity Capture-MS
REST BioGRID RPS29 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPS26 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPS25 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPS24 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPS23 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPS20 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPS19 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPS18 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPS17 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPS16 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPS15A GeneID BioGRID Affinity Capture-MS
REST BioGRID RPS14 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPS13 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPS11 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPS10 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPS9 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPS8 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPS7 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPS6 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPS4X GeneID BioGRID Affinity Capture-MS
REST BioGRID RPS3A GeneID BioGRID Affinity Capture-MS
REST BioGRID RPS3 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPS2 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPLP2 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPLP1 GeneID BioGRID Affinity Capture-MS
REST BioGRID CCDC180 GeneID BioGRID Affinity Capture-MS
REST BioGRID KNOP1 GeneID BioGRID Affinity Capture-MS
REST BioGRID CYSRT1 GeneID BioGRID Affinity Capture-MS
REST BioGRID ACTBL2 GeneID BioGRID Affinity Capture-MS
REST BioGRID H3C15 GeneID BioGRID Affinity Capture-MS
REST BioGRID LCN12 GeneID BioGRID Affinity Capture-MS
REST BioGRID HNRNPA3 GeneID BioGRID Affinity Capture-MS
REST BioGRID TUBB GeneID BioGRID Affinity Capture-MS
REST BioGRID COL22A1 GeneID BioGRID Affinity Capture-MS
REST BioGRID SDE2 GeneID BioGRID Affinity Capture-MS
REST BioGRID EEF1A1P5 GeneID BioGRID Affinity Capture-MS
REST BioGRID DOCK11 GeneID BioGRID Affinity Capture-MS
REST BioGRID PDCL2 GeneID BioGRID Affinity Capture-MS
REST BioGRID H2BC26 GeneID BioGRID Affinity Capture-MS
REST BioGRID SAMD1 GeneID BioGRID Affinity Capture-MS
REST BioGRID KIAA1671 GeneID BioGRID Affinity Capture-MS
REST BioGRID TUBA1C GeneID BioGRID Affinity Capture-MS
REST BioGRID MRPL24 GeneID BioGRID Affinity Capture-MS
REST BioGRID C1orf35 GeneID BioGRID Affinity Capture-MS
REST BioGRID GNPTAB GeneID BioGRID Affinity Capture-MS
REST BioGRID DDX54 GeneID BioGRID Affinity Capture-MS
REST BioGRID MRPL11 GeneID BioGRID Affinity Capture-MS
REST BioGRID MRPS26 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPLP0 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPL36A GeneID BioGRID Affinity Capture-MS
REST BioGRID RPL38 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPL37A GeneID BioGRID Affinity Capture-MS
REST BioGRID RPL35A GeneID BioGRID Affinity Capture-MS
REST BioGRID RPL34 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPL31 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPL29 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPL28 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPL27A GeneID BioGRID Affinity Capture-MS
REST BioGRID RPL30 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPL27 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPL26 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPL24 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPL23A GeneID BioGRID Affinity Capture-MS
REST BioGRID RPL22 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPL21 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPL19 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPL18A GeneID BioGRID Affinity Capture-MS
REST BioGRID RPL18 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPL17 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPL15 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPL13 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPL12 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPL11 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPL10 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPL9 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPL8 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPL7A GeneID BioGRID Affinity Capture-MS
REST BioGRID RPL7 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPL6 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPL5 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPL4 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPL3 GeneID BioGRID Affinity Capture-MS
REST BioGRID RFC1 GeneID BioGRID Affinity Capture-MS
REST BioGRID RBM3 GeneID BioGRID Affinity Capture-MS
REST BioGRID RBBP7 GeneID BioGRID Affinity Capture-MS
REST BioGRID MOK GeneID BioGRID Affinity Capture-MS
REST BioGRID PSME1 GeneID BioGRID Affinity Capture-MS
REST BioGRID PPP1CB GeneID BioGRID Affinity Capture-MS
REST BioGRID PPID GeneID BioGRID Affinity Capture-MS
REST BioGRID POLR2E GeneID BioGRID Affinity Capture-MS
REST BioGRID YBX1 GeneID BioGRID Affinity Capture-MS
REST BioGRID NPM1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-localization
REST BioGRID NONO GeneID BioGRID Affinity Capture-MS
REST BioGRID RPL10A GeneID BioGRID Affinity Capture-MS
REST BioGRID NCL GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-localization
REST BioGRID HNRNPM GeneID BioGRID Affinity Capture-MS
REST BioGRID LMNB1 GeneID BioGRID Affinity Capture-MS
REST BioGRID LGALS3BP GeneID BioGRID Affinity Capture-MS
REST BioGRID RPSA GeneID BioGRID Affinity Capture-MS
REST BioGRID KPNA2 GeneID BioGRID Affinity Capture-MS
REST BioGRID JARID2 GeneID BioGRID Affinity Capture-MS
REST BioGRID ILF3 GeneID BioGRID Affinity Capture-MS
REST BioGRID ILF2 GeneID BioGRID Affinity Capture-MS
REST BioGRID HSPE1 GeneID BioGRID Affinity Capture-MS
REST BioGRID HSPA9 GeneID BioGRID Affinity Capture-MS
REST BioGRID HSPA8 GeneID BioGRID Affinity Capture-MS
REST BioGRID HSPA5 GeneID BioGRID Affinity Capture-MS
REST BioGRID HSPA1A GeneID BioGRID Affinity Capture-MS
REST BioGRID HNRNPU GeneID BioGRID Affinity Capture-MS
REST BioGRID HNRNPL GeneID BioGRID Affinity Capture-MS
REST BioGRID HNRNPF GeneID BioGRID Affinity Capture-MS
REST BioGRID HNRNPD GeneID BioGRID Affinity Capture-MS
REST BioGRID HNRNPAB GeneID BioGRID Affinity Capture-MS
REST BioGRID HMGA1 GeneID BioGRID Affinity Capture-MS
REST BioGRID HMGN1 GeneID BioGRID Affinity Capture-MS
REST BioGRID DMAP1 GeneID BioGRID Affinity Capture-MS
REST BioGRID LYAR GeneID BioGRID Affinity Capture-MS
REST BioGRID MRGBP GeneID BioGRID Affinity Capture-MS
REST BioGRID H2BC12L GeneID BioGRID Affinity Capture-MS
REST BioGRID AMOTL2 GeneID BioGRID Affinity Capture-MS
REST BioGRID DDX47 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPS27L GeneID BioGRID Affinity Capture-MS
REST BioGRID STRN4 GeneID BioGRID Affinity Capture-MS
REST BioGRID IGKV4-1 GeneID BioGRID Affinity Capture-MS
REST BioGRID HTATSF1 GeneID BioGRID Affinity Capture-MS
REST BioGRID RBMX GeneID BioGRID Affinity Capture-MS
REST BioGRID PABPC1 GeneID BioGRID Affinity Capture-MS
REST BioGRID SERBP1 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPL13A GeneID BioGRID Affinity Capture-MS
REST BioGRID SF3B1 GeneID BioGRID Affinity Capture-MS
REST BioGRID RALY GeneID BioGRID Affinity Capture-MS
REST BioGRID CBX3 GeneID BioGRID Affinity Capture-MS
REST BioGRID RPL35 GeneID BioGRID Affinity Capture-MS
REST BioGRID EZH2 GeneID BioGRID Affinity Capture-MS
REST BioGRID SUZ12 GeneID BioGRID Affinity Capture-MS
REST BioGRID MEPCE GeneID BioGRID Affinity Capture-MS
REST BioGRID ZNF598 GeneID BioGRID Affinity Capture-MS
REST BioGRID FOXK2 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-purification
REST BioGRID AURKA GeneID BioGRID Reconstituted Complex
REST BioGRID RCOR1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
REST BioGRID MAPK1 GeneID BioGRID Biochemical Activity
REST BioGRID PIN1 GeneID BioGRID Affinity Capture-Western
REST BioGRID CTDSP1 GeneID BioGRID Affinity Capture-Western
REST BioGRID Wiz GeneID BioGRID Affinity Capture-MS
REST BioGRID SCYL1 GeneID BioGRID Affinity Capture-Western
REST BioGRID TEX14 GeneID BioGRID Affinity Capture-Western
REST BioGRID FBXW11 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
REST BioGRID PLK1 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
REST BioGRID UBC GeneID BioGRID Affinity Capture-Western
REST BioGRID CSNK1E GeneID BioGRID Affinity Capture-Western
REST BioGRID EHMT2 GeneID BioGRID Affinity Capture-Western
REST BioGRID EIF4A3 GeneID BioGRID Affinity Capture-MS
REST BioGRID FBXW4 GeneID BioGRID Affinity Capture-Western
REST BioGRID FBXW7 GeneID BioGRID Affinity Capture-Western
REST BioGRID FBXW5 GeneID BioGRID Affinity Capture-Western
REST BioGRID FBXW8 GeneID BioGRID Affinity Capture-Western
REST BioGRID FBXW2 GeneID BioGRID Affinity Capture-Western
REST BioGRID SIN3A GeneID BioGRID Affinity Capture-Western
REST BioGRID TERF2 GeneID BioGRID Affinity Capture-Western; Co-localization
REST BioGRID GRIA2 GeneID BioGRID Affinity Capture-Western
REST BioGRID SUB1 GeneID BioGRID Affinity Capture-Western; Co-localization; Reconstituted Complex
REST BioGRID GTF2B GeneID BioGRID Reconstituted Complex
REST BioGRID Gtf2b GeneID BioGRID Reconstituted Complex
REST BioGRID Tbp GeneID BioGRID Reconstituted Complex
REST BioGRID SIN3B GeneID BioGRID Affinity Capture-Western
REST BioGRID TBP GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
REST BioGRID HDAC1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
REST BioGRID SP1 GeneID BioGRID Affinity Capture-Western
REST BioGRID SMARCE1 GeneID BioGRID Affinity Capture-Western
REST BioGRID SMARCC2 GeneID BioGRID Affinity Capture-Western
REST BioGRID SMARCA4 GeneID BioGRID Affinity Capture-Western
REST BioGRID CDYL GeneID BioGRID Affinity Capture-MS; Reconstituted Complex
REST BioGRID HDAC4 GeneID BioGRID Affinity Capture-Western
REST Protein SIN3B GeneID HPRD
REST Protein RCOR1 GeneID HPRD
REST Protein HTT GeneID HPRD
REST BioGRID NCOR1 GeneID BioGRID Affinity Capture-MS
REST BioGRID KDM5C GeneID BioGRID Affinity Capture-MS
REST BioGRID RNF2 GeneID BioGRID Affinity Capture-MS
REST BioGRID HDAC2 GeneID BioGRID Affinity Capture-MS
REST BioGRID Hdac1 GeneID BioGRID Reconstituted Complex
REST BioGRID Sin3b GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
REST BioGRID Sin3a GeneID BioGRID Reconstituted Complex
REST Protein STMN2 GeneID BIND NRSF/REST interacts with SCG10 promoter in the region of the NRSE/RE1 (neuron restrictive silencer element).
REST Protein GRM2 GeneID BIND NRSF/REST interacts with mGluR2 promoter in the region of the NRSE/RE1 (neuron restrictive silencer element).
REST Protein CTDSP1 GeneID BIND SCP1 interacts with REST.
REST Protein EHMT2 GeneID BIND NRSF interacts with G9a.
StringDB
A B experiments database textmining combined score hadb nhadb
REST XPO6 0 0 91 195 1 1
REST BRE 0 0 48 195 1 1
REST DDX3X 270 0 0 283 1 1
REST POU2F1 0 0 135 169 1 1
REST RPLP0 270 0 48 286 1 1
REST TUBB4B 270 0 0 282 1 1
REST HNRNPD 270 0 0 282 1 1
REST YBX1 270 0 66 301 1 1
REST SNAP25 0 0 223 223 1 1
REST WIZ 0 0 108 163 1 1
REST STAG1 0 0 0 585 1 1
REST BDNF 0 0 562 562 1 2
REST CDK5R2 0 0 264 310 1 1
REST MUS81 0 0 332 347 1 1
REST RPS10 270 0 0 270 1 1
REST ESRRB 0 0 157 187 1 1
REST SUV39H2 0 0 93 164 1 1
REST MAPK1 270 0 63 356 1 2
REST IGF1 0 0 149 168 1 2
REST NR0B1 0 0 0 386 1 1
REST ATN1 0 500 103 544 1 1
REST CUL4B 0 0 96 179 1 1
REST HIST1H4H 0 0 246 278 1 1
REST SEC23IP 270 0 0 278 1 1
REST SOX5 0 0 112 167 1 1
REST SH3GL3 0 0 297 297 1 1
REST KMT2A 0 0 88 169 1 1
REST CDK17 0 0 71 192 1 1
REST FOXK2 270 0 87 349 1 1
REST FGF2 0 0 245 256 1 2
REST FAU 270 0 0 312 1 2
REST PSIP1 270 0 0 270 1 1
REST JUND 0 0 294 338 1 1
REST MEIS1 0 0 105 154 1 1
REST CCND1 0 0 203 232 1 2
REST PSME1 270 0 0 281 1 1
REST HIST2H2BE 88 900 232 925 1 1
REST SCG3 0 0 140 158 1 1
REST OLIG2 0 0 243 256 1 1
REST KAT2B 0 0 193 264 1 1
REST KRT20 0 0 48 165 1 1
REST L3MBTL2 0 0 0 199 1 1
REST GRIK5 0 0 0 155 1 1
REST SSBP1 270 0 0 286 1 1
REST LCP1 0 0 329 339 1 1
REST SNRPA1 270 0 0 290 1 1
REST DMAP1 270 0 0 281 1 1
REST OPRM1 0 0 364 373 1 1
REST SAP18 0 600 181 664 1 1
REST RUNX1 0 0 71 169 1 2
REST MYCBP2 0 0 156 173 1 1
REST ARID4A 0 600 0 641 1 1
REST ANK2 0 0 0 225 1 1
REST HOXC12 0 0 181 263 1 1
REST DCLK2 0 0 0 215 1 1
REST HIST2H4B 0 0 246 278 1 1
REST KCNQ5 0 0 150 322 1 1
REST GLUL 0 0 108 169 1 1
REST MAF1 0 650 0 657 1 1
REST RTEL1 0 0 122 215 1 1
REST PGBD5 0 0 142 433 1 1
REST USP7 0 0 244 316 1 1
REST ARHGAP32 0 0 229 281 1 1
REST DCX 0 0 265 265 1 1
REST ZNF488 270 0 0 286 1 1
REST PRDM2 0 0 157 171 1 1
REST TUBB2A 0 0 328 339 1 1
REST HIST1H4D 0 0 246 278 1 1
REST RNF2 270 650 156 774 1 1
REST HIST1H2BJ 270 900 64 930 1 1
REST SKP1 0 0 125 214 1 2
REST YY1 0 0 427 227 1 1
REST RPL11 270 0 0 270 1 1
REST COL28A1 0 0 88 308 1 1
REST TRIM28 270 0 194 409 1 2
REST TAF4 0 0 210 232 1 1
REST S100A6 0 0 304 304 1 1
REST EWSR1 270 0 157 369 1 1
REST ALYREF 270 0 0 284 1 1
REST ZBED6CL 0 0 170 169 1 1
REST POU4F1 0 0 113 200 1 1
REST HNF4A 0 0 219 349 1 1
REST FOXO3 0 0 134 167 1 2
REST FBXW5 270 0 45 273 1 1
REST APOE 0 0 160 177 1 2
REST C1QBP 270 0 0 285 1 1
REST SIN3B 887 0 294 935 1 1
REST TLL2 0 0 0 189 1 1
REST MPHOSPH8 0 0 0 156 1 1
REST NME1-NME2 0 0 109 220 1 1
REST HIST1H2BN 270 900 0 929 1 1
REST PITX3 0 0 216 288 1 1
REST CTCFL 0 0 325 193 1 1
REST TH 0 0 222 222 1 2
REST NGF 0 0 269 269 1 2
REST RPL29 270 0 0 290 1 1
REST RALY 270 0 0 282 1 1
REST HMGA1 270 0 0 270 1 1
REST NTRK2 0 0 325 352 1 1
REST CDK8 0 0 143 209 1 1
REST RPLP2 270 0 0 281 1 1
REST KMT2D 0 0 135 235 1 1
REST RPL35 270 0 0 270 1 1
REST MTMR4 270 0 0 270 1 1
REST DROSHA 0 0 240 275 1 1
REST E2F4 0 0 234 265 1 1
REST HIST1H4C 0 0 246 278 1 1
REST CTDP1 0 0 218 239 1 1
REST LHX3 0 0 155 209 1 1
REST RPL26 270 0 0 270 1 1
REST SUMO1 0 0 74 172 1 1
REST GNL1 0 0 150 181 1 1
REST CDKN2B 0 0 113 173 1 1
REST MET 0 0 74 152 1 2
REST LRRK2 0 0 154 277 1 2
REST GRIN2B 0 0 325 335 1 1
REST STK38L 0 0 0 167 1 1
REST IFT57 0 0 212 212 1 1
REST HNRNPAB 270 0 0 300 1 1
REST CHRM4 0 0 170 169 1 1
REST NELFA 0 0 113 224 1 1
REST FZD5 0 0 45 172 1 1
REST ST6GAL2 0 0 134 193 1 1
REST HIST1H2AH 0 900 0 903 1 1
REST FOS 0 0 393 406 1 2
REST AMOTL2 270 0 0 270 1 1
REST RPL10 270 0 0 270 1 1
REST RPS15A 270 0 0 281 1 1
REST MTCL1 0 0 85 161 1 1
REST DNM1 0 0 74 202 1 1
REST HSPA5 270 0 45 285 1 2
REST FOXP2 0 0 97 150 1 1
REST TFE3 0 0 0 160 1 2
REST FGF20 0 0 170 182 1 1
REST BTRC 873 0 324 914 1 1
REST CAMK4 0 0 82 163 1 1
REST SAP25 0 0 187 187 1 1
REST USF2 0 0 218 246 1 1
REST WNT2 0 0 45 163 1 1
REST HIST2H4A 0 0 246 278 1 1
REST KCNQ2 0 0 195 260 1 1
REST RPS4X 270 0 95 322 1 1
REST HDAC1 486 800 954 995 1 2
REST CHD8 0 0 150 245 1 1
REST MEF2A 0 0 142 171 1 1
REST DAXX 0 0 150 243 1 1
REST POU6F2 0 0 653 661 1 1
REST LIMK1 0 0 143 229 1 1
REST CYP26A1 0 0 218 230 1 1
REST RPSA 270 0 0 283 1 1
REST MED26 0 0 150 222 1 1
REST TET1 0 0 212 243 1 1
REST NR2C2 0 0 158 194 1 1
REST GRM1 0 0 142 231 1 1
REST RPL31 270 0 0 270 1 1
REST SUDS3 0 600 168 665 1 1
REST ZBTB33 0 0 204 204 1 1
REST FHL1 270 0 0 283 1 1
REST BMP4 0 0 211 235 1 1
REST WT1 0 0 440 217 1 1
REST ONECUT2 0 0 91 253 1 1
REST WDR1 0 0 45 168 1 1
REST ENSG00000258947 0 0 240 270 1 1
REST MAPK14 0 0 73 163 1 2
REST HIST1H4A 0 0 246 278 1 1
REST KDM5C 270 0 731 820 1 1
REST NFIA 0 0 171 227 1 1
REST IRF4 0 0 154 153 1 1
REST BARHL1 0 0 81 236 1 1
REST PTEN 0 0 235 266 1 2
REST RPS29 270 0 0 287 1 1
REST MYOD1 0 0 218 233 1 1
REST RPS20 270 0 0 270 1 1
REST POU6F1 0 0 211 276 1 1
REST KNOP1 270 0 0 270 1 1
REST OTX1 0 0 90 207 1 1
REST TAC1 0 0 118 151 1 1
REST RPL21 270 0 0 270 1 1
REST RPL38 270 0 0 282 1 1
REST CHD4 0 600 134 670 1 1
REST GFAP 0 0 293 304 1 2
REST RFX5 0 0 180 209 1 1
REST PPARGC1B 0 0 66 167 1 1
REST RPS3A 270 0 0 270 1 1
REST RBPJ 0 0 166 220 1 1
REST HIST1H1C 270 0 0 285 1 1
REST NRXN1 0 0 537 537 1 1
REST RPS13 270 0 0 270 1 1
REST RPS18 270 0 0 270 1 1
REST RPL18A 270 0 0 290 1 1
REST POU2F2 0 0 133 151 1 1
REST STMN1 0 0 431 439 1 1
REST RPS23 270 0 0 281 1 1
REST NOVA1 0 0 577 587 1 1
REST HNRNPK 0 0 174 200 1 1
REST NCAM1 0 0 123 156 1 1
REST PTBP3 0 0 52 172 1 1
REST KDM5B 0 0 124 258 1 1
REST RCOR1 835 800 988 999 1 1
REST COL22A1 270 0 0 283 1 1
REST DYRK1A 0 0 537 575 1 1
REST CHD3 0 600 64 639 1 1
REST GUCY1B3 0 0 57 291 1 1
REST POLE4 0 0 0 197 1 1
REST ARID1A 0 0 442 454 1 1
REST GRIN1 0 0 136 235 1 1
REST CRH 0 0 259 258 1 1
REST SOX6 0 0 115 170 1 1
REST SPAG6 0 0 57 164 1 1
REST SP3 0 0 411 356 1 1
REST HIPK2 0 0 112 186 1 2
REST FUS 0 0 141 154 1 2
REST SPI1 0 0 243 242 1 1
REST SMARCA4 486 0 646 827 1 1
REST SIRT1 0 0 293 305 1 2
REST HIST1H2AD 0 900 0 903 1 1
REST PCDH1 0 0 46 334 1 1
REST BACE1 0 0 233 252 1 2
REST TUBB 270 0 328 497 1 1
REST GATA2 0 0 181 336 1 1
REST ACTL6B 0 0 417 487 1 1
REST EHMT1 0 0 425 470 1 1
REST RIF1 0 0 91 335 1 1
REST RBBP4 0 600 234 726 1 1
REST CBX4 0 650 67 666 1 1
REST RPL15 270 0 0 270 1 1
REST SF3A2 270 0 0 284 1 1
REST RPL27 270 0 0 282 1 1
REST CDS2 0 0 107 151 1 1
REST USP15 0 0 233 249 1 1
REST SCN2A 0 0 297 307 1 1
REST NLGN2 0 0 415 424 1 1
REST NOVA2 0 0 145 214 1 1
REST TCERG1 0 0 134 282 1 1
REST PPARGC1A 0 0 157 227 1 2
REST CBX5 0 0 120 153 1 1
REST RPL35A 270 0 0 270 1 1
REST SOX11 0 0 251 297 1 1
REST SYNJ1 270 0 74 314 1 1
REST HNRNPU 270 0 81 332 1 1
REST USP39 0 0 122 154 1 1
REST PITX1 0 0 0 184 1 1
REST BRCA1 0 0 146 179 1 2
REST STK11 0 0 61 154 1 2
REST MED19 0 0 450 459 1 1
REST GLRA2 0 0 143 156 1 1
REST PPP1R1B 0 0 181 181 1 1
REST RFC1 270 0 0 288 1 1
REST RCOR3 0 0 361 640 1 1
REST HIST1H2BH 270 900 0 929 1 1
REST DLX2 0 0 244 259 1 1
REST MTA1 0 600 167 658 1 1
REST CHGA 0 0 232 231 1 1
REST CYSRT1 270 0 0 270 1 1
REST HDAC2 270 800 471 925 1 1
REST EMX1 0 0 142 160 1 1
REST GATAD2B 0 600 89 626 1 1
REST NCOR2 0 0 194 326 1 1
REST RPL28 270 0 0 270 1 1
REST ASB7 0 0 0 155 1 1
REST LHX1 0 0 62 175 1 1
REST HNRNPR 270 0 74 306 1 1
REST HTT 213 800 946 992 1 2
REST MAOA 0 0 120 159 1 1
REST MDM2 270 0 107 320 1 2
REST TP53 0 650 370 778 1 2
REST SATB2 0 0 143 187 1 1
REST KCND3 0 0 253 264 1 1
REST SFPQ 270 0 47 274 1 1
REST GSX2 0 0 204 218 1 1
REST SOX4 0 0 150 203 1 1
REST MELK 0 0 0 161 1 1
REST CALM3 0 0 67 159 1 1
REST BRD4 0 0 113 215 1 2
REST VGF 0 900 199 918 1 1
REST ZNF335 0 0 283 185 1 1
REST MTA3 0 600 134 644 1 1
REST HDAC6 0 0 193 263 1 2
REST APAF1 0 0 55 183 1 2
REST PASK 0 0 0 171 1 1
REST BAZ1A 0 0 53 168 1 1
REST DCLK3 0 0 55 190 1 1
REST WDR25 0 0 155 154 1 1
REST ARC 0 0 113 194 1 2
REST SP140L 0 0 0 173 1 1
REST CTNNB1 0 0 287 301 1 2
REST APP 0 0 285 284 1 2
REST EGR1 0 650 324 694 1 2
REST SUMO2 0 0 113 222 1 1
REST DLX4 0 0 66 180 1 1
REST PAX2 0 0 123 169 1 1
REST RPL30 270 0 0 270 1 1
REST PHC1 0 650 67 688 1 1
REST RPL12 270 0 0 270 1 1
REST ISL1 0 0 180 449 1 1
REST POU4F2 0 0 74 216 1 1
REST STAT1 0 0 340 354 1 2
REST KCNMA1 0 0 171 190 1 1
REST CXXC1 0 0 212 225 1 1
REST SRSF9 270 0 0 282 1 1
REST TCF20 0 0 193 256 1 1
REST RPL9 270 0 0 270 1 1
REST IGFBP7 0 0 96 152 1 1
REST TBL1XR1 0 0 154 199 1 1
REST MTOR 0 0 155 189 1 2
REST JARID2 270 0 124 399 1 1
REST EVI5L 0 0 0 225 1 1
REST HIST1H4F 486 0 246 613 1 1
REST HCN2 0 0 166 165 1 1
REST L1CAM 0 0 181 426 1 1
REST TRAPPC8 0 0 67 174 1 1
REST TRIP12 0 0 0 168 1 1
REST GJD2 0 0 257 256 1 1
REST GRIK2 0 0 71 180 1 1
REST SIRT2 0 0 204 218 1 2
REST ZFX 0 0 250 151 1 1
REST MYT1L 0 0 261 272 1 1
REST RPS27L 270 0 0 282 1 1
REST CTNND1 0 0 435 468 1 1
REST DHX9 270 0 44 285 1 1
REST HIST2H2AC 0 900 218 920 1 1
REST USP44 0 0 124 159 1 1
REST KHDRBS1 0 0 114 170 1 1
REST CREB1 0 650 459 811 1 2
REST FGF14 0 0 155 168 1 1
REST USP9X 0 0 76 154 1 1
REST SDHB 0 0 134 158 1 1
REST FRAS1 0 0 0 278 1 1
REST NFE2 0 0 140 171 1 1
REST CREBBP 0 0 251 337 1 1
REST FOXD4L1 0 0 118 153 1 1
REST DGCR8 0 0 202 263 1 1
REST TERF2 270 0 0 270 1 1
REST PPID 270 0 0 298 1 1
REST TCF7L2 0 0 84 175 1 1
REST HDAC10 0 0 108 178 1 1
REST EBF1 0 0 172 218 1 1
REST DYNC1I1 0 0 398 413 1 1
REST PTBP1 0 0 455 584 1 2
REST HIST4H4 0 0 246 278 1 1
REST PML 0 0 296 322 1 2
REST SLC6A5 0 0 47 214 1 1
REST GAPDH 0 0 282 282 1 2
REST KAT6A 0 0 108 175 1 1
REST RPL13 270 0 0 270 1 1
REST ABLIM2 0 0 540 540 1 1
REST LGALS3BP 270 0 0 270 1 1
REST PHF10 0 0 327 336 1 1
REST GNRHR 0 0 0 377 1 1
REST EVI5 0 0 0 226 1 1
REST SNRPD3 270 0 0 281 1 1
REST SLC8A1 0 0 143 243 1 1
REST ZBTB3 0 0 95 157 1 1
REST HMG20B 0 600 390 766 1 1
REST RERE 270 0 0 289 1 1
REST INA 0 0 166 193 1 1
REST CCNA2 0 0 107 158 1 1
REST JUN 0 650 265 748 1 2
REST RPL37A 270 0 0 270 1 1
REST TAF1 0 0 342 369 1 1
REST FBL 270 0 0 270 1 2
REST CTDSP2 0 0 721 725 1 1
REST RPL3 270 0 0 270 1 1
REST SMC3 0 0 185 215 1 1
REST BMI1 0 0 218 230 1 1
REST SOD1 0 0 150 165 1 2
REST TBL1X 0 0 137 204 1 1
REST KPNA2 270 0 0 298 1 1
REST CENPE 0 0 0 153 1 1
REST ANKRD44 0 0 0 177 1 1
REST GTF2F1 0 0 357 367 1 1
REST PHC2 0 650 0 656 1 1
REST MAX 0 0 84 459 1 2
REST GRIN2A 0 0 286 297 1 1
REST JAG1 0 0 140 153 1 1
REST BARHL2 0 0 57 382 1 1
REST ID4 0 0 143 179 1 1
REST RUNX3 0 0 84 195 1 1
REST PRKACB 0 0 0 184 1 1
REST HIST1H2BK 0 900 0 905 1 1
REST PUM2 0 0 57 153 1 1
REST UCHL1 0 0 173 195 1 2
REST GAP43 0 0 138 157 1 1
REST RING1 0 650 107 684 1 1
REST RPL24 270 0 0 270 1 1
REST AURKA 270 0 120 375 1 2
REST SYN1 0 0 417 416 1 1
REST AR 0 0 414 436 1 2
REST GNRH1 0 0 54 156 1 1
REST NR1D2 270 0 47 305 1 1
REST CDKN1A 0 0 144 159 1 2
REST PHOX2A 0 0 147 162 1 1
REST SLC32A1 0 0 122 158 1 1
REST NEUROG1 0 0 284 298 1 1
REST SOX9 0 0 283 327 1 1
REST SF3B2 270 0 0 281 1 1
REST HUNK 0 0 70 207 1 1
REST PSEN1 0 0 181 199 1 2
REST ATF2 0 650 81 682 1 1
REST CCDC180 270 0 0 270 1 1
REST SOX2 0 0 405 442 1 2
REST SP100 0 0 95 279 1 1
REST HIST2H2AA3 0 0 218 241 1 1
REST HDAC4 270 0 868 908 1 2
REST ZMYM2 0 0 155 235 1 1
REST CTBP1 0 0 443 463 1 1
REST SIM2 0 0 120 158 1 1
REST SUB1 270 0 0 270 1 1
REST STK38 0 0 0 167 1 1
REST MAPK3 0 0 119 205 1 2
REST HIST2H2AA 0 0 218 241 1 1
REST RPS2 270 0 0 270 1 1
REST RAD21L1 0 0 0 268 1 1
REST HNRNPF 270 0 57 300 1 1
REST PLS3 0 0 310 320 1 1
REST ONECUT1 0 0 113 502 1 1
REST SOX15 0 0 101 176 1 1
REST GGH 0 0 0 188 1 1
REST PTBP2 0 0 322 391 1 1
REST BRWD1 0 0 125 194 1 1
REST EP300 0 650 363 797 1 2
REST CHD1 0 0 193 307 1 1
REST CDK5 0 0 170 193 1 2
REST SLC12A2 0 0 151 164 1 1
REST LEF1 0 0 66 159 1 1
REST PRMT3 0 0 45 257 1 1
REST ILF3 270 0 0 270 1 1
REST ELAVL1 270 0 134 340 1 2
REST CUL1 0 0 137 188 1 1
REST ADAMTS6 270 0 0 281 1 1
REST SNAI2 0 650 104 668 1 1
REST RPL19 270 0 0 307 1 1
REST ALB 0 0 157 156 1 2
REST PEX5L 0 0 134 166 1 1
REST MAP1B 0 0 134 205 1 2
REST ZNF395 0 0 412 412 1 1
REST PAX6 0 0 699 710 1 1
REST PPP1CB 270 0 0 320 1 1
REST DRD2 0 0 164 177 1 1
REST GATA1 0 0 243 273 1 1
REST H3F3B 0 0 61 159 1 1
REST MAF 0 0 134 169 1 1
REST SMARCE1 270 0 266 450 1 1
REST PDGFRA 0 0 112 164 1 1
REST IGF2BP1 270 0 0 270 1 1
REST CDH1 0 0 148 171 1 2
REST NEUROG2 0 0 308 320 1 1
REST SCG2 0 0 217 217 1 1
REST HIST1H2BO 0 900 0 907 1 1
REST SGK494 0 0 0 181 1 1
REST SIRT6 0 0 143 158 1 2
REST BRAF 270 0 46 303 1 2
REST NR2E1 0 600 358 741 1 1
REST CTDSPL 0 0 728 734 1 1
REST CHERP 270 0 0 270 1 1
REST MBTD1 0 0 0 172 1 1
REST SAMD1 270 0 0 325 1 1
REST HIST1H2AA 0 900 0 903 1 1
REST PHF8 0 0 238 253 1 1
REST ZNF217 0 0 260 257 1 1
REST MIER2 0 0 123 366 1 1
REST EXD3 0 0 143 152 1 1
REST TUFM 270 0 0 270 1 2
REST XPO5 0 0 174 277 1 1
REST NGB 0 0 204 216 1 1
REST CHAT 0 0 266 282 1 1
REST HIST3H2A 0 900 0 906 1 1
REST PDE6B 0 0 134 176 1 1
REST MRPL24 270 0 0 270 1 1
REST NFYA 0 0 234 265 1 1
REST GATA4 0 0 486 506 1 2
REST RPLP1 270 0 0 281 1 1
REST SMARCA2 0 0 193 252 1 1
REST HSPA4 0 0 63 177 1 1
REST DICER1 0 0 306 327 1 1
REST RPL17 270 0 0 270 1 1
REST BMP2 0 0 150 165 1 1
REST EGF 0 0 276 276 1 2
REST SP4 0 0 0 181 1 1
REST DOCK11 270 0 0 270 1 1
REST ZZZ3 0 0 180 227 1 1
REST SLC1A2 0 0 170 169 1 1
REST GADD45B 0 0 134 175 1 1
REST HIST2H2BF 0 900 0 904 1 1
REST CARF 0 0 306 409 1 1
REST DDX17 270 0 48 288 1 1
REST RCAN1 0 0 412 421 1 2
REST USP14 0 0 138 158 1 2
REST SLC2A4RG 0 0 357 357 1 1
REST ATXN7 0 0 180 200 1 1
REST RBBP7 270 600 236 790 1 1
REST FMR1 0 0 236 249 1 1
REST RBFOX3 0 0 292 306 1 1
REST TDG 0 0 166 165 1 1
REST HMG20A 0 0 138 243 1 1
REST KDM3A 0 0 166 165 1 1
REST KCND2 0 0 150 163 1 1
REST NR4A2 0 0 206 222 1 1
REST MEF2C 0 0 162 190 1 1
REST RPL18 270 0 0 270 1 1
REST SIN3A 486 800 852 991 1 1
REST ATF3 0 0 183 200 1 2
REST USP19 0 0 96 150 1 1
REST HIST1H2AJ 270 900 0 926 1 1
REST FBXW2 270 0 0 296 1 1
REST SIX5 0 0 282 368 1 1
REST EZH1 0 0 136 203 1 1
REST ESCO1 0 0 135 189 1 1
REST TMPRSS2 0 0 161 161 1 1
REST TFAP2A 0 0 167 231 1 1
REST TLE2 0 0 0 187 1 1
REST SSU72 0 0 123 182 1 1
REST RPL7A 270 0 0 270 1 1
REST MEPCE 270 0 0 278 1 1
REST DLX6 0 0 134 152 1 1
REST SAP30 0 600 123 642 1 1
REST HNRNPA3 270 0 46 286 1 1
REST HDAC7 0 500 124 580 1 1
REST KCNQ4 0 0 93 261 1 1
REST HIST1H4B 0 0 246 278 1 1
REST PDCL2 270 0 134 360 1 1
REST NCOR1 270 0 401 593 1 1
REST CDK1 0 0 77 168 1 2
REST HGNC:9982 0 0 180 209 1 1
REST RPS9 270 0 0 270 1 1
REST DRD1 0 0 122 154 1 1
REST CC2D1A 0 0 415 415 1 1
REST HSPA9 270 0 0 341 1 1
REST PRMT8 0 0 63 177 1 1
REST HTATSF1 270 0 0 270 1 1
REST GLRA1 0 0 167 180 1 1
REST NTRK1 0 0 128 164 1 1
REST NUMBL 0 0 156 170 1 1
REST SRRM3 0 0 342 342 1 1
REST POU5F1 0 0 391 490 1 2
REST MECOM 0 650 0 650 1 1
REST GRIA1 0 0 181 193 1 1
REST ADAMTS3 0 0 0 167 1 1
REST MRGBP 270 0 0 285 1 1
REST TAL1 0 0 245 264 1 1
REST CAT 270 0 61 298 1 2
REST DNAJB2 0 0 55 170 1 1
REST LIN28A 0 0 157 190 1 1
REST FOXA2 0 0 172 203 1 1
REST RNASEL 0 0 0 153 1 1
REST SAP30L 0 600 0 603 1 1
REST GTF2B 270 0 120 366 1 1
REST CTCF 0 0 631 311 1 1
REST KDM5A 0 0 194 310 1 1
REST EIF2S1 270 0 0 270 1 2
REST ELK4 0 0 163 404 1 1
REST CBX2 0 650 381 779 1 1
REST SF3B1 270 0 0 285 1 1
REST NFATC2 0 0 329 339 1 1
REST FBXW11 764 0 46 776 1 1
REST SRSF7 270 0 0 270 1 1
REST ABLIM1 0 0 292 292 1 1
REST SLC25A5 270 0 0 292 1 1
REST NEUROD2 0 0 265 278 1 1
REST TCF12 0 650 213 717 1 1
REST GAD1 0 0 181 211 1 1
REST FOXJ2 0 0 86 169 1 1
REST LCN12 270 0 0 270 1 1
REST KDM6A 0 0 142 254 1 1
REST CUX2 0 0 95 285 1 1
REST MRPS26 270 0 0 270 1 1
REST SMARCC1 0 0 365 458 1 1
REST RPS8 270 0 0 270 1 1
REST TUBA1C 270 0 0 282 1 1
REST ACTL6A 0 0 390 524 1 1
REST SRC 0 0 99 156 1 2
REST EED 0 650 235 740 1 1
REST IGF2R 0 0 44 185 1 1
REST MAFK 0 0 210 223 1 1
REST SHBG 0 0 270 270 1 1
REST ILF2 270 0 0 270 1 1
REST CDYL2 0 0 0 204 1 1
REST SIRT4 0 0 147 342 1 1
REST CHRD 0 0 113 168 1 1
REST ATOH1 0 0 150 226 1 1
REST TCERG1L 0 0 0 157 1 1
REST KCNJ2 0 0 108 195 1 1
REST ANK3 0 0 71 316 1 1
REST HIST3H2BB 270 0 0 313 1 1
REST CELSR3 0 0 181 193 1 1
REST HIST2H2AB 0 900 0 903 1 1
REST STAG3 0 0 0 294 1 1
REST SP140 0 0 0 173 1 1
REST PPARG 0 650 162 705 1 2
REST UBE3A 0 0 123 177 1 1
REST AKT1 0 0 232 263 1 2
REST ATF1 0 650 45 659 1 1
REST HIST1H2BA 0 900 0 907 1 1
REST SYT4 0 0 256 267 1 1
REST CPE 0 0 90 258 1 1
REST FOXA1 0 0 325 351 1 1
REST RPL23A 270 0 0 286 1 1
REST ORAI3 0 0 82 173 1 1
REST SMARCD3 0 0 134 167 1 1
REST MAPT 0 0 216 247 1 2
REST SCAMP5 0 0 95 260 1 1
REST HIST1H2BB 0 900 0 907 1 1
REST SRRM4 0 0 425 477 1 1
REST SRSF5 270 0 0 282 1 1
REST ZMYND8 0 0 163 278 1 1
REST DLX5 0 0 155 172 1 1
REST ITPKA 0 0 171 171 1 1
REST TMPO 0 0 0 181 1 1
REST SRP14 270 0 0 270 1 1
REST RXRA 0 0 154 184 1 1
REST RPS11 270 0 0 282 1 1
REST KDM6B 0 0 145 280 1 1
REST COL12A1 270 0 0 282 1 1
REST WDR59 0 0 0 154 1 1
REST HNRNPA0 270 0 0 282 1 1
REST ZNF598 270 0 0 276 1 1
REST RPS14 270 0 0 270 1 1
REST ONECUT3 0 0 0 212 1 1
REST SYNCRIP 270 0 46 309 1 1
REST ASCL1 0 650 423 794 1 1
REST NTF3 0 0 157 173 1 1
REST CACNA1H 0 0 234 245 1 1
REST CDKN2A 0 0 141 192 1 2
REST RPS27A 270 0 0 297 1 1
REST MOK 270 0 0 280 1 1
REST RIMS3 0 0 84 225 1 1
REST GSK3B 0 0 74 152 1 2
REST SALL4 0 650 0 672 1 1
REST S100B 0 0 180 179 1 1
REST PHC3 0 650 66 665 1 1
REST MORF4L1 0 0 141 193 1 1
REST CBX8 0 650 0 657 1 1
REST BANF1 0 0 324 344 1 1
REST NPAS4 0 0 265 287 1 1
REST CEBPB 0 0 223 254 1 2
REST SOX1 0 0 216 265 1 1
REST MBD4 0 0 137 153 1 1
REST SH3GL2 0 0 270 270 1 1
REST CASP3 0 0 162 195 1 2
REST HNRNPL 270 0 85 312 1 1
REST SLITRK1 0 0 134 225 1 1
REST HDAC9 0 0 170 235 1 1
REST BZW1 0 0 72 224 1 1
REST HDAC11 0 0 236 296 1 1
REST RAD21 0 0 322 360 1 1
REST NME2 0 0 113 224 1 1
REST INSM1 0 0 415 415 1 1
REST SMARCA1 0 0 136 193 1 1
REST HOXC11 0 0 145 245 1 1
REST H2BFS 270 0 55 320 1 1
REST RPL34 270 0 0 288 1 1
REST COMMD3-BMI1 0 0 218 230 1 1
REST KAT5 0 0 113 198 1 1
REST RPS24 270 0 0 270 1 1
REST RCOR2 0 0 391 780 1 1
REST HIST1H4K 0 0 246 278 1 1
REST CHL1 0 0 123 217 1 1
REST MTA2 0 600 174 661 1 1
REST RPL10A 270 0 0 270 1 1
REST NTRK3 0 0 204 250 1 1
REST NFATC1 0 0 328 338 1 2
REST DMD 270 0 0 281 1 2
REST SMARCC2 270 0 307 533 1 1
REST FOSB 0 0 124 228 1 1
REST DLG4 0 0 219 240 1 2
REST DYRK1B 0 0 46 170 1 1
REST FOSL2 0 0 103 177 1 1
REST SNAI1 0 650 134 672 1 1
REST MATR3 270 0 0 281 1 1
REST NPM1 270 0 66 322 1 1
REST SRSF3 270 0 66 289 1 1
REST TAF1L 0 0 310 338 1 1
REST KCNA2 0 0 141 229 1 1
REST BRMS1 0 600 74 619 1 1
REST GAD2 0 0 207 247 1 1
REST SOX10 0 0 125 179 1 1
REST LYAR 270 0 0 281 1 1
REST MFSD4 0 0 0 248 1 1
REST RPL5 270 0 0 271 1 1
REST PRKCA 0 0 172 172 1 1
REST RIPK4 0 0 0 153 1 1
REST SETD2 0 0 108 177 1 1
REST DLX1 0 0 210 231 1 1
REST TBP 270 0 243 441 1 1
REST NONO 270 0 62 285 1 1
REST GATAD2A 0 600 113 651 1 1
REST KCNN4 0 0 377 386 1 1
REST PRLHR 0 0 224 236 1 1
REST TET2 0 0 159 172 1 2
REST RAB3A 0 0 90 153 1 1
REST UBC 270 0 112 363 1 2
REST LAMA1 0 0 307 334 1 1
REST TEAD4 0 0 150 196 1 1
REST DYNC1H1 0 0 0 248 1 1
REST SYP 0 0 325 325 1 1
REST OTX2 0 0 146 248 1 1
REST RPL27A 270 0 0 270 1 1
REST RPL23 270 0 0 270 1 1
REST ATOH7 0 0 155 287 1 1
REST MIB1 0 0 57 166 1 1
REST LMNB1 270 0 122 359 1 1
REST SERBP1 270 0 0 281 1 1
REST TLE3 0 0 0 218 1 1
REST EOMES 0 0 167 265 1 1
REST INPP5K 0 0 0 167 1 1
REST H2AFY 270 0 45 375 1 1
REST ACTBL2 270 0 0 311 1 1
REST HOMER1 0 0 163 163 1 1
REST UBE2D2 0 0 83 174 1 1
REST ESR1 0 0 247 274 1 2
REST NCL 270 0 82 312 1 2
REST CDYL 270 0 156 481 1 1
REST RARG 0 0 96 161 1 1
REST TFAP2B 0 0 48 383 1 1
REST BDP1 0 0 138 178 1 1
REST MAP2 0 0 108 163 1 2
REST NOG 0 0 167 167 1 1
REST CTDSP1 847 0 724 957 1 1
REST RUVBL2 270 0 0 295 1 1
REST STRN4 270 0 0 285 1 1
REST SDHC 0 0 181 218 1 1
REST USF1 0 0 392 464 1 1
REST H1F0 270 0 142 361 1 1
REST SNRPE 270 0 0 281 1 2
REST HIST1H2BD 308 900 0 933 1 1
REST MYC 0 0 393 422 1 2
REST FABP7 0 0 113 192 1 1
REST SLC6A4 0 0 142 198 1 1
REST DDX47 270 0 0 283 1 1
REST RPS26 270 0 0 282 1 1
REST RPS17 270 0 42 282 1 1
REST HIST1H2BM 0 900 0 901 1 1
REST MECP2 0 0 595 603 1 1
REST FBXW8 270 0 46 300 1 1
REST EHMT2 486 0 724 863 1 2
REST ENSG00000272772 0 0 0 156 1 1
REST RPS19 270 0 0 270 1 1
REST RPS25 270 0 0 270 1 1
REST KCNN3 0 0 87 179 1 1
REST NGDN 0 0 64 179 1 1
REST SPAG5 270 0 0 285 1 1
REST HDAC3 0 500 150 620 1 2
REST HIST1H4L 0 0 246 278 1 1
REST MYCN 0 0 294 308 1 1
REST SMAD4 0 0 150 172 1 2
REST HDAC5 486 500 241 812 1 1
REST MED13 0 0 134 234 1 1
REST PRKX 0 0 50 191 1 1
REST PABPC1 270 0 49 313 1 1
REST PRKACG 0 0 0 184 1 1
REST PITX2 0 0 90 174 1 1
REST ARPC2 0 0 52 164 1 1
REST RPS16 270 0 0 270 1 1
REST NRXN3 0 0 647 647 1 1
REST STAU1 0 0 122 204 1 1
REST SLAIN1 0 0 82 194 1 1
REST HIST1H4I 0 0 246 278 1 1
REST SLC12A5 0 0 340 350 1 1
REST SCN10A 0 0 243 254 1 1
REST USP37 0 0 218 276 1 1
REST DDX54 270 0 0 283 1 1
REST ZNF143 0 0 379 182 1 1
REST AGO2 0 0 161 199 1 2
REST POU5F1B 0 0 0 197 1 1
REST SRSF6 270 0 0 282 1 1
REST STAT3 0 0 261 293 1 2
REST DEAF1 0 0 170 212 1 1
REST EZH2 42 650 392 801 1 2
REST EFCAB2 0 0 0 168 1 1
REST NR2F1 0 0 120 152 1 1
REST ELAVL2 0 0 123 155 1 1
REST GATA3 0 0 117 209 1 1
REST PIN1 270 0 61 297 1 1
REST PAX4 0 0 306 331 1 1
REST SRSF1 270 0 90 319 1 1
REST CTBP2 0 0 162 195 1 1
REST TGM1 0 0 294 294 1 1
REST SNRPD1 270 0 0 281 1 2
REST TEX14 270 0 122 331 1 1
REST TPR 0 0 415 439 1 1
REST RBM3 270 0 0 282 1 1
REST KDM7A 0 0 96 158 1 1
REST G3BP2 270 0 0 282 1 1
REST HMGN1 270 0 50 290 1 1
REST HCN4 0 0 193 193 1 1
REST XPO1 0 0 0 172 1 1
REST CDK2 0 0 93 187 1 2
REST MTMR6 0 0 109 230 1 1
REST KCNQ1 0 0 93 168 1 1
REST KIAA1429 270 0 53 294 1 1
REST GABPA 0 0 193 206 1 1
REST ID1 0 0 141 173 1 1
REST HIF1A 0 0 142 157 1 2
REST SIRT5 0 0 139 154 1 1
REST RPS7 270 0 0 282 1 1
REST ZMYM3 0 0 150 224 1 1
REST IL1B 0 0 164 163 1 2
REST SP1 270 0 302 391 1 2
REST H3F3A 0 0 61 159 1 1
REST CBX3 270 0 113 350 1 1
REST BRD2 0 0 71 153 1 1
REST E2F6 282 0 217 425 1 1
REST RPS6 270 0 0 282 1 2
REST SUMO4 0 0 0 159 1 1
REST MYSM1 0 0 0 154 1 1
REST IL6 0 0 162 161 1 2
REST NFYB 0 0 252 286 1 1
REST RPL13A 270 0 0 270 1 1
REST TBR1 0 0 151 202 1 1
REST DDX21 270 0 0 305 1 1
REST FBXW4 270 0 0 270 1 1
REST SDE2 270 0 0 270 1 1
REST ZNF648 0 0 170 239 1 1
REST PRICKLE1 0 0 324 336 1 1
REST FGF13 0 0 166 179 1 1
REST PSEN2 0 0 134 153 1 1
REST LYPLA1 0 0 122 179 1 1
REST PRMT1 0 0 62 176 1 1
REST RPL14 270 0 0 282 1 1
REST CCNC 0 0 140 156 1 1
REST NOTCH1 0 0 322 332 1 2
REST MAST1 0 0 0 180 1 1
REST PLK1 270 0 118 339 1 2
REST RELN 0 0 203 203 1 1
REST GRIA2 270 0 288 466 1 1
REST NPPA 0 0 164 163 1 1
REST RPS3 270 0 0 270 1 1
REST BAP1 0 0 123 181 1 1
REST STAG2 0 0 0 368 1 1
REST PRKACA 0 0 0 184 1 1
REST TAF15 270 0 0 281 1 1
REST CTDSPL2 0 0 123 157 1 1
REST C1orf35 270 0 55 280 1 1
REST POU3F2 0 0 324 338 1 1
REST SLC18A3 0 0 218 218 1 1
REST SCYL1 270 0 235 430 1 1
REST ATRX 0 0 166 240 1 1
REST HIST1H2AC 270 900 0 927 1 1
REST NF1 0 0 125 154 1 1
REST CHD7 0 0 116 213 1 1
REST OLIG1 0 0 218 231 1 1
REST HMGB2 0 0 102 261 1 1
REST DNMT3B 0 0 261 289 1 1
REST MAPK8IP1 0 0 135 174 1 1
REST UHRF1 0 0 108 160 1 1
REST DNMT3A 0 0 298 324 1 2
REST RNPS1 0 0 0 166 1 1
REST CBX6 0 650 0 657 1 1
REST TLL1 0 0 52 310 1 1
REST RPL36A 270 0 61 285 1 1
REST HSPA1A 270 0 0 285 1 1
REST SRF 0 0 218 243 1 1
REST NPC2 0 0 0 642 1 1
REST SNCA 0 0 216 216 1 2
REST PHF21A 0 600 294 737 1 1
REST BATF 0 0 171 410 1 1
REST DCAF10 0 0 0 151 1 1
REST STMN3 0 0 230 242 1 1
REST RPL7 270 0 0 270 1 1
REST MAFB 0 0 92 163 1 1
REST OR8J1 0 0 158 288 1 1
REST RBMX 270 0 0 284 1 1
REST WDR5 0 0 142 175 1 1
REST CALB1 0 0 216 237 1 1
REST NR2F2 0 0 119 151 1 1
REST NRF1 0 0 146 159 1 2
REST MIB2 0 0 0 152 1 1
REST MED12 0 0 277 292 1 1
REST SHH 0 0 298 335 1 2
REST TLE4 0 0 0 218 1 1
REST NKX2-2 0 0 210 224 1 1
REST ANK1 0 0 0 177 1 1
REST TPH2 0 0 247 246 1 1
REST H1FX 270 0 0 285 1 1
REST TET3 0 0 235 263 1 1
REST KDM4A 0 0 163 204 1 1
REST RPL4 270 0 0 270 1 1
REST CAPN2 0 0 60 168 1 2
REST SPOP 0 0 0 157 1 1
REST SLC16A6 0 0 0 206 1 1
REST TCF7 0 0 107 224 1 1
REST AGRN 270 0 0 270 1 1
REST ATP5B 270 0 0 348 1 1
REST ISL2 0 0 54 245 1 1
REST USP50 0 0 167 240 1 1
REST SETMAR 0 0 66 159 1 1
REST KDM1A 0 800 727 946 1 2
REST PIWIL1 0 0 223 248 1 1
REST TARDBP 0 0 124 227 1 2
REST HIST1H2BL 0 900 0 903 1 1
REST HNRNPM 270 0 48 301 1 1
REST PARP1 270 0 108 321 1 2
REST MBD3 0 600 0 614 1 1
REST HSPA8 270 0 0 285 1 2
REST POU3F4 0 0 140 188 1 1
REST DPF3 0 0 153 178 1 1
REST MXI1 0 0 234 247 1 1
REST PHPT1 0 0 157 245 1 1
REST RPL8 270 0 0 287 1 1
REST RPL22 270 0 0 270 1 1
REST SUV39H1 0 0 261 318 1 1
REST DYRK2 0 0 415 464 1 1
REST KDM1B 0 0 316 347 1 1
REST SETD1A 0 0 124 192 1 1
REST CEBPA 0 0 203 560 1 1
REST NEUROD1 0 0 554 562 1 1
REST HAPLN3 0 0 66 209 1 1
REST FBXW7 270 0 107 345 1 2
REST SETDB1 0 0 294 349 1 1
REST PAX8 0 0 0 161 1 1
REST ARID4B 0 600 0 641 1 1
REST HIST1H4J 0 0 246 278 1 1
REST PBX3 0 0 217 233 1 1
REST KMT2C 0 0 90 184 1 1
REST SIRT3 0 0 150 165 1 2
REST CSNK1E 270 0 0 303 1 1
REST HSPE1 270 0 0 270 1 1
REST PAX5 0 0 142 187 1 1
REST DPF1 0 0 325 345 1 1
REST STUB1 0 0 134 154 1 2
REST DNMT1 0 0 340 362 1 2
REST TLE1 0 0 103 404 1 1
REST FOXG1 0 0 233 262 1 1
REST INS 0 0 195 195 1 2
REST ACTB 0 0 218 262 1 2
REST CNTF 0 0 155 154 1 1
REST TUBB3 0 0 260 287 1 1
REST CTBS 0 0 107 162 1 1
REST SPOPL 0 0 0 158 1 1
REST NRCAM 0 0 108 203 1 1
REST HCFC1 0 0 189 189 1 1
REST HIST2H3D 270 0 0 303 1 1
REST KAT2A 0 0 145 220 1 1
REST PIWIL4 0 0 218 230 1 1
REST USP28 0 0 124 199 1 1
REST STMN2 0 0 578 610 1 1
REST CAMK2N1 0 0 85 157 1 1
REST DCLK1 0 0 55 328 1 1
REST CUX1 0 0 166 380 1 1
REST LBX1 0 0 55 234 1 1
REST HTR1A 0 0 240 254 1 1
REST SUZ12 42 650 329 787 1 1
REST LGALS4 0 0 207 221 1 1
REST OR8J3 0 0 0 190 1 1
REST FRK 0 0 0 176 1 1
REST RPL6 270 0 0 282 1 1
REST MFGE8 0 0 0 155 1 1
REST UBE2D4 0 0 0 166 1 1
REST HIST1H4E 0 0 246 278 1 1
REST HDAC8 0 0 155 227 1 1
REST CDK6 0 0 74 158 1 2
REST KMT2B 0 0 142 217 1 1
REST PRPH2 0 0 150 307 1 1
REST NEUROG3 0 0 181 195 1 1
REST ADAMTS2 0 0 0 151 1 1
REST FOXP1 0 0 136 191 1 1
REST ENO2 0 0 170 182 1 1
REST ABLIM3 0 0 307 307 1 1
REST SUMO3 0 0 0 159 1 1
REST GNPTAB 270 0 0 270 1 1
REST MEIS2 0 0 108 160 1 1
REST POLR2E 270 0 0 275 1 1
REST HES5 0 0 261 261 1 1
REST HNMT 0 0 163 163 1 1
REST NR3C1 0 0 234 311 1 1
REST H2AFZ 0 0 216 245 1 1
REST SMARCB1 0 0 170 480 1 1
REST HIST2H3PS2 0 0 459 483 1 1
REST NFIC 0 0 143 199 1 1
REST NES 0 0 323 323 1 2
REST BPTF 0 0 107 533 1 1
REST MRPL11 270 0 0 285 1 1
REST KIAA1671 270 0 0 270 1 1
REST SNRPN 270 0 0 281 1 1
REST SCMH1 0 650 82 677 1 1
REST SMARCA5 270 0 108 366 1 1
REST SETD7 0 0 84 155 1 1
REST NRXN2 0 0 647 647 1 1
REST SLC6A11 0 0 108 169 1 1
REST EIF4A3 195 0 0 210 1 1
REST ESCO2 0 0 134 181 1 1
REST ETS1 0 0 166 179 1 1
REST NANOG 0 0 414 500 1 2
REST RPS6KA3 0 0 57 152 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0003700 Molecular Function DNA-binding transcription factor activity enables IDA
GO:0001227 Molecular Function DNA-binding transcription repressor activity, RNA polymerase II-specific enables IBA
GO:0001227 Molecular Function DNA-binding transcription repressor activity, RNA polymerase II-specific enables IDA
GO:0001227 Molecular Function DNA-binding transcription repressor activity, RNA polymerase II-specific enables IMP
GO:0000978 Molecular Function RNA polymerase II cis-regulatory region sequence-specific DNA binding enables IDA
GO:0000978 Molecular Function RNA polymerase II cis-regulatory region sequence-specific DNA binding enables IMP
GO:0000979 Molecular Function RNA polymerase II core promoter sequence-specific DNA binding enables IEA
GO:0061629 Molecular Function RNA polymerase II-specific DNA-binding transcription factor binding enables IPI
GO:0003682 Molecular Function chromatin binding enables ISS
GO:0046872 Molecular Function metal ion binding enables IEA
GO:0005515 Molecular Function protein binding enables IPI
GO:0000976 Molecular Function transcription cis-regulatory region binding enables IBA
GO:0000976 Molecular Function transcription cis-regulatory region binding enables IDA
GO:0060379 Biological Process cardiac muscle cell myoblast differentiation involved_in ISS
GO:0071257 Biological Process cellular response to electrical stimulus involved_in IMP
GO:0071385 Biological Process cellular response to glucocorticoid stimulus involved_in IDA
GO:0071466 Biological Process cellular response to xenobiotic stimulus involved_in IMP
GO:0006338 Biological Process chromatin remodeling involved_in ISS
GO:0002244 Biological Process hematopoietic progenitor cell differentiation involved_in IEA
GO:0099563 Biological Process modification of synaptic structure involved_in ISS
GO:0043922 Biological Process negative regulation by host of viral transcription involved_in IDA
GO:0045892 Biological Process negative regulation of DNA-templated transcription involved_in IBA
GO:0045892 Biological Process negative regulation of DNA-templated transcription involved_in IDA
GO:0045892 Biological Process negative regulation of DNA-templated transcription involved_in IMP
GO:0045892 Biological Process negative regulation of DNA-templated transcription involved_in NAS
GO:0032348 Biological Process negative regulation of aldosterone biosynthetic process involved_in IMP
GO:2000798 Biological Process negative regulation of amniotic stem cell differentiation involved_in IMP
GO:0045955 Biological Process negative regulation of calcium ion-dependent exocytosis involved_in ISS
GO:0008285 Biological Process negative regulation of cell population proliferation involved_in IMP
GO:2000065 Biological Process negative regulation of cortisol biosynthetic process involved_in IMP
GO:2000706 Biological Process negative regulation of dense core granule biogenesis involved_in ISS
GO:0010629 Biological Process negative regulation of gene expression involved_in IMP
GO:0046676 Biological Process negative regulation of insulin secretion involved_in IMP
GO:2000740 Biological Process negative regulation of mesenchymal stem cell differentiation involved_in IMP
GO:1902894 Biological Process negative regulation of miRNA transcription involved_in IMP
GO:0050768 Biological Process negative regulation of neurogenesis involved_in ISS
GO:0045665 Biological Process negative regulation of neuron differentiation involved_in IBA
GO:0045665 Biological Process negative regulation of neuron differentiation involved_in IDA
GO:0045665 Biological Process negative regulation of neuron differentiation involved_in IMP
GO:0000122 Biological Process negative regulation of transcription by RNA polymerase II involved_in IDA
GO:0000122 Biological Process negative regulation of transcription by RNA polymerase II involved_in TAS
GO:0050877 Biological Process nervous system process involved_in IMP
GO:0097150 Biological Process neuronal stem cell population maintenance involved_in ISS
GO:0045893 Biological Process positive regulation of DNA-templated transcription involved_in IDA
GO:0043065 Biological Process positive regulation of apoptotic process involved_in IMP
GO:0043280 Biological Process positive regulation of cysteine-type endopeptidase activity involved in apoptotic process involved_in IMP
GO:0045666 Biological Process positive regulation of neuron differentiation involved_in ISS
GO:0043068 Biological Process positive regulation of programmed cell death involved_in ISS
GO:1902459 Biological Process positive regulation of stem cell population maintenance involved_in IDA
GO:0045944 Biological Process positive regulation of transcription by RNA polymerase II involved_in IBA
GO:0006355 Biological Process regulation of DNA-templated transcription involved_in NAS
GO:0000381 Biological Process regulation of alternative mRNA splicing, via spliceosome involved_in ISS
GO:0045667 Biological Process regulation of osteoblast differentiation involved_in ISS
GO:0001666 Biological Process response to hypoxia involved_in IDA
GO:0002931 Biological Process response to ischemia involved_in ISS
GO:0035019 Biological Process somatic stem cell population maintenance involved_in ISS
GO:0005737 Cellular Component cytoplasm located_in IDA
GO:0005829 Cellular Component cytosol located_in IDA
GO:0005654 Cellular Component nucleoplasm located_in IDA
GO:0005654 Cellular Component nucleoplasm located_in TAS
GO:0005634 Cellular Component nucleus is_active_in IBA
GO:0005634 Cellular Component nucleus located_in IDA
GO:0005634 Cellular Component nucleus located_in IMP
GO:0005634 Cellular Component nucleus located_in NAS
GO:0017053 Cellular Component transcription repressor complex part_of IBA
GO:0017053 Cellular Component transcription repressor complex part_of IDA
Pathways
Name DB ID
PIP3 activates AKT signaling Reactome R-HSA-1257604
Signal Transduction Reactome R-HSA-162582
Disease Reactome R-HSA-1643685
Signaling by NTRKs Reactome R-HSA-166520
Signaling by NTRK1 (TRKA) Reactome R-HSA-187037
Nuclear Events (kinase and transcription factor activation) Reactome R-HSA-198725
Generic Transcription Pathway Reactome R-HSA-212436
HDACs deacetylate histones Reactome R-HSA-3214815
Chromatin modifying enzymes Reactome R-HSA-3247509
Chromatin organization Reactome R-HSA-4839726
Infectious disease Reactome R-HSA-5663205
PTEN Regulation Reactome R-HSA-6807070
RNA Polymerase II Transcription Reactome R-HSA-73857
Gene expression (Transcription) Reactome R-HSA-74160
Regulation of PTEN gene transcription Reactome R-HSA-8943724
Intracellular signaling by second messengers Reactome R-HSA-9006925
Signaling by Receptor Tyrosine Kinases Reactome R-HSA-9006934
NGF-stimulated transcription Reactome R-HSA-9031628
Transcriptional Regulation by NPAS4 Reactome R-HSA-9634815
Potential therapeutics for SARS Reactome R-HSA-9679191
SARS-CoV Infections Reactome R-HSA-9679506
Regulation of NPAS4 gene expression Reactome R-HSA-9768759
Regulation of NPAS4 gene transcription Reactome R-HSA-9768777
Viral Infection Pathways Reactome R-HSA-9824446
MECP2 and associated Rett syndrome (WP3584) WikiPathways WP3584_r123274
Sudden infant death syndrome (SIDS) susceptibility pathways (WP706) WikiPathways WP706_r117178
DYRK1A (WP5180) WikiPathways WP5180_r122423
Transcripts
Accession Version MolecularType Name NCBI Comments
NM_005612 5 mRNA transcript variant 1 NC_000004 Reference
XM_017008527 2 mRNA transcript variant X1 NC_000004 Reference
NM_001363453 2 mRNA transcript variant 3 NC_000004 Reference
NM_001193508 1 mRNA transcript variant 2 NC_000004 Reference
XM_047416053 1 mRNA transcript variant X2 NC_000004 Reference