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BIK

BCL2 interacting killer
General Information
Name BCL2 interacting killer
Alias
  • bcl-2-interacting killer
  • BCL2-interacting killer (apoptosis-inducing)
  • apoptosis inducer NBK
  • apoptosis-inducing NBK
  • natural born killer
Gene_family BCL2 homology region 3 (BH3) only
organism Homo sapiens
entrez_id 638
location 22q13.2
transcript_count 1
exon_count 5
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins. [provided by RefSeq, Sep 2011]
    Stringdb Bcl-2-interacting killer; Accelerates programmed cell death. Association to the apoptosis repressors Bcl-X(L), BHRF1, Bcl-2 or its adenovirus homolog E1B 19k protein suppresses this death-promoting activity. Does not interact with BAX; BCL2 homology region 3 only
    nextProt Accelerates programmed cell death. Association to the apoptosis repressors Bcl-X(L), BHRF1, Bcl-2 or its adenovirus homolog E1B 19k protein suppresses this death-promoting activity. Does not interact with BAX.
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
BIK BioGRID BMF GeneID BioGRID Negative Genetic
BIK BioGRID PMAIP1 GeneID BioGRID Negative Genetic
BIK BioGRID BNIP3L GeneID BioGRID Negative Genetic
BIK BioGRID BNIP3 GeneID BioGRID Negative Genetic; Two-hybrid
BIK BioGRID BID GeneID BioGRID Negative Genetic
BIK BioGRID BAX GeneID BioGRID Negative Genetic
BIK BioGRID BAK1 GeneID BioGRID Negative Genetic
BIK BioGRID BAD GeneID BioGRID Negative Genetic
BIK BioGRID CSNK2A1 GeneID BioGRID Affinity Capture-Western
BIK BioGRID BCL2L10 GeneID BioGRID Affinity Capture-Western; Two-hybrid
BIK BioGRID BCL2 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Protein-peptide; Two-hybrid
BIK BioGRID ASB11 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
BIK BioGRID ASB17 GeneID BioGRID Affinity Capture-Western
BIK BioGRID ANKRD9 GeneID BioGRID Affinity Capture-Western
BIK BioGRID CUL5 GeneID BioGRID Affinity Capture-Western
BIK BioGRID VCP GeneID BioGRID Affinity Capture-Western
BIK BioGRID SMIM1 GeneID BioGRID Two-hybrid
BIK BioGRID SERP2 GeneID BioGRID Two-hybrid
BIK BioGRID TRARG1 GeneID BioGRID Two-hybrid
BIK BioGRID BRICD5 GeneID BioGRID Two-hybrid
BIK BioGRID TMEM80 GeneID BioGRID Two-hybrid
BIK BioGRID TMEM86B GeneID BioGRID Two-hybrid
BIK BioGRID TSPO2 GeneID BioGRID Two-hybrid
BIK BioGRID FAM241B GeneID BioGRID Two-hybrid
BIK BioGRID FAM209A GeneID BioGRID Two-hybrid
BIK BioGRID PLPP4 GeneID BioGRID Two-hybrid
BIK BioGRID TMEM229B GeneID BioGRID Two-hybrid
BIK BioGRID ANKRD46 GeneID BioGRID Two-hybrid
BIK BioGRID CLDN19 GeneID BioGRID Two-hybrid
BIK BioGRID CNIH3 GeneID BioGRID Two-hybrid
BIK BioGRID TMEM199 GeneID BioGRID Two-hybrid
BIK BioGRID CMTM5 GeneID BioGRID Two-hybrid
BIK BioGRID SCAMP4 GeneID BioGRID Two-hybrid
BIK BioGRID CMTM7 GeneID BioGRID Two-hybrid
BIK BioGRID EXOC3L2 GeneID BioGRID Two-hybrid
BIK BioGRID FATE1 GeneID BioGRID Two-hybrid
BIK BioGRID TMEM60 GeneID BioGRID Two-hybrid
BIK BioGRID TMEM107 GeneID BioGRID Two-hybrid
BIK BioGRID TMEM222 GeneID BioGRID Two-hybrid
BIK BioGRID TMEM14B GeneID BioGRID Two-hybrid
BIK BioGRID CYB5B GeneID BioGRID Two-hybrid
BIK BioGRID REEP4 GeneID BioGRID Two-hybrid
BIK BioGRID TMEM254 GeneID BioGRID Two-hybrid
BIK BioGRID C3orf52 GeneID BioGRID Two-hybrid
BIK BioGRID TMEM243 GeneID BioGRID Two-hybrid
BIK BioGRID ALG8 GeneID BioGRID Two-hybrid
BIK BioGRID RUSF1 GeneID BioGRID Two-hybrid
BIK BioGRID TMBIM1 GeneID BioGRID Two-hybrid
BIK BioGRID SELENOK GeneID BioGRID Two-hybrid
BIK BioGRID CXCL16 GeneID BioGRID Two-hybrid
BIK BioGRID SLC35E3 GeneID BioGRID Two-hybrid
BIK BioGRID MARCHF5 GeneID BioGRID Two-hybrid
BIK BioGRID ERGIC3 GeneID BioGRID Two-hybrid
BIK BioGRID TMEM14C GeneID BioGRID Two-hybrid
BIK BioGRID AIG1 GeneID BioGRID Two-hybrid
BIK BioGRID INSIG2 GeneID BioGRID Two-hybrid
BIK BioGRID ADGRE2 GeneID BioGRID Two-hybrid
BIK BioGRID UBIAD1 GeneID BioGRID Two-hybrid
BIK BioGRID TMEM97 GeneID BioGRID Two-hybrid
BIK BioGRID PGAP2 GeneID BioGRID Two-hybrid
BIK BioGRID BMP10 GeneID BioGRID Two-hybrid
BIK BioGRID SERP1 GeneID BioGRID Two-hybrid
BIK BioGRID SEC22A GeneID BioGRID Two-hybrid
BIK BioGRID NRM GeneID BioGRID Two-hybrid
BIK BioGRID PGRMC1 GeneID BioGRID Two-hybrid
BIK BioGRID VAMP5 GeneID BioGRID Two-hybrid
BIK BioGRID FAM3C GeneID BioGRID Two-hybrid
BIK BioGRID BTN2A2 GeneID BioGRID Two-hybrid
BIK BioGRID CNIH1 GeneID BioGRID Two-hybrid
BIK BioGRID STX8 GeneID BioGRID Two-hybrid
BIK BioGRID ADIPOQ GeneID BioGRID Two-hybrid
BIK BioGRID VAMP3 GeneID BioGRID Two-hybrid
BIK BioGRID NAT8 GeneID BioGRID Two-hybrid
BIK BioGRID TMEM11 GeneID BioGRID Two-hybrid
BIK BioGRID SLC39A7 GeneID BioGRID Two-hybrid
BIK BioGRID ZFPL1 GeneID BioGRID Two-hybrid
BIK BioGRID ELOVL4 GeneID BioGRID Two-hybrid
BIK BioGRID PLP2 GeneID BioGRID Two-hybrid
BIK BioGRID PLP1 GeneID BioGRID Two-hybrid
BIK BioGRID PLN GeneID BioGRID Two-hybrid
BIK BioGRID PBX3 GeneID BioGRID Two-hybrid
BIK BioGRID KCNN4 GeneID BioGRID Two-hybrid
BIK BioGRID GRM2 GeneID BioGRID Two-hybrid
BIK BioGRID SLC37A4 GeneID BioGRID Two-hybrid
BIK BioGRID FCGR1A GeneID BioGRID Two-hybrid
BIK BioGRID CYB561 GeneID BioGRID Two-hybrid
BIK BioGRID CD72 GeneID BioGRID Two-hybrid
BIK BioGRID CD53 GeneID BioGRID Two-hybrid
BIK BioGRID BCL2L2 GeneID BioGRID Affinity Capture-Western; Protein-peptide; Two-hybrid
BIK BioGRID BCL2L1 GeneID BioGRID Affinity Capture-Western; Protein-peptide; Two-hybrid
BIK BioGRID BCL2A1 GeneID BioGRID Protein-peptide; Two-hybrid
BIK BioGRID APOD GeneID BioGRID Two-hybrid
BIK BioGRID CTXN3 GeneID BioGRID Two-hybrid
BIK BioGRID STRIT1 GeneID BioGRID Two-hybrid
BIK BioGRID MS4A13 GeneID BioGRID Two-hybrid
BIK BioGRID GPX8 GeneID BioGRID Two-hybrid
BIK BioGRID C4orf3 GeneID BioGRID Two-hybrid
BIK BioGRID C14orf180 GeneID BioGRID Two-hybrid
BIK BioGRID S100A1 GeneID BioGRID Two-hybrid
BIK BioGRID CREB3 GeneID BioGRID Two-hybrid
BIK BioGRID MCL1 GeneID BioGRID Protein-peptide; Reconstituted Complex
BIK BioGRID TANK GeneID BioGRID Two-hybrid
BIK BioGRID SOCS3 GeneID BioGRID Two-hybrid
BIK BioGRID NR2F2 GeneID BioGRID Two-hybrid
BIK BioGRID CRKL GeneID BioGRID Two-hybrid
BIK BioGRID APP GeneID BioGRID Reconstituted Complex
BIK BioGRID RHBDL3 GeneID BioGRID Affinity Capture-Western
BIK Protein MCL1 GeneID HPRD
BIK Protein BCL2L2 GeneID HPRD
BIK Protein BCL2A1 GeneID HPRD
BIK Protein BCL2L1 GeneID HPRD
BIK Protein BCL2 GeneID HPRD
BIK Protein BNC1 GeneID BIND Bik interacts with Mcl-1. This interaction was modelled on a demonstrated interaction between human Bik and mouse Mcl-1.
BIK Protein BCL2 GeneID BIND Bik interacts with Bcl-2.
BIK Protein BCL2L1 GeneID BIND Bik interacts with Bcl-XL.
BIK Protein BCL2A1 GeneID BIND Bik interacts with A1. This interaction was modelled on a demonstrated interaction between human Bik and mouse A1.
BIK Protein BCL2L2 GeneID BIND Bik interacts with Bcl-w.
BIK Protein BCL2L1 GeneID BIND Bcl-XL interacts with Bik. This interaction was modelled on a demonstrated interaction between Bcl-XL from an unspecified species and human Bik.
BIK Protein BCL2 GeneID BIND Bcl-2 interacts with Bik.
StringDB
A B experiments database textmining combined score hadb nhadb
BIK SOX4 0 0 74 234 1 1
BIK ERN1 0 0 324 338 1 2
BIK ASB1 0 0 102 164 1 1
BIK HRK 0 0 802 822 1 1
BIK STAT3 0 0 166 165 1 2
BIK EZH2 0 0 217 217 1 2
BIK VDAC2 0 0 268 268 1 1
BIK PXT1 0 0 153 315 1 1
BIK CANX 0 0 212 212 1 2
BIK RHBDL3 270 0 0 270 1 1
BIK APAF1 0 900 528 950 1 2
BIK BAK1 0 0 529 542 1 2
BIK BCL2 880 900 283 990 1 2
BIK CISD2 0 0 293 293 1 2
BIK NR4A1 0 0 181 181 1 2
BIK DFFA 0 0 160 202 1 1
BIK CTBP2 0 0 193 193 1 1
BIK ENSG00000197584 0 0 181 181 1 1
BIK TRAF1 0 0 147 166 1 1
BIK MXD4 0 0 124 152 1 1
BIK CCND1 0 0 213 213 1 2
BIK SERPINA4 0 0 214 214 1 1
BIK PDCL 0 0 231 230 1 1
BIK LIPH 0 0 75 152 1 1
BIK PANO 0 0 260 260 1 1
BIK TNFRSF11B 0 0 112 211 1 1
BIK CRADD 0 0 267 279 1 1
BIK TACC1 0 0 67 165 1 1
BIK BCL2L2 872 0 795 972 1 1
BIK DDIT3 0 0 323 323 1 2
BIK S100A1 174 0 0 173 1 1
BIK BNIP2 0 0 136 269 1 1
BIK MDM2 0 0 246 245 1 2
BIK TP53 0 0 537 537 1 2
BIK HSPA9 0 0 134 153 1 1
BIK BAD 0 0 460 471 1 2
BIK EGFR 0 0 227 226 1 2
BIK CFLAR 0 0 335 335 1 2
BIK CDK4 0 0 134 152 1 2
BIK NUDT11 0 0 187 187 1 1
BIK STX8 75 0 150 180 1 2
BIK CDK1 0 0 146 162 1 2
BIK FADD 0 0 325 325 1 2
BIK ASB7 0 0 107 171 1 1
BIK CIDEA 0 0 213 213 1 1
BIK TDGF1 0 0 150 172 1 1
BIK RELT 0 0 150 208 1 1
BIK GADD45A 0 0 284 284 1 1
BIK IFI35 0 0 66 274 1 1
BIK MAP2K1 0 0 171 171 1 1
BIK BRCA1 0 0 173 173 1 2
BIK ATF3 0 0 181 192 1 2
BIK AREG 0 0 47 169 1 1
BIK IFNW1 0 0 81 220 1 1
BIK KDELR1 0 0 167 167 1 1
BIK BCAP31 0 0 167 167 1 1
BIK SPATA31A7 0 0 208 208 1 1
BIK CIDEB 0 0 156 196 1 1
BIK GPR78 0 0 162 161 1 1
BIK RELB 0 0 142 167 1 2
BIK BCL2A1 876 0 741 966 1 1
BIK NOL3 0 0 219 236 1 1
BIK BMF 0 0 812 812 1 1
BIK CD70 0 0 246 246 1 1
BIK ASB11 270 0 130 482 1 1
BIK ACMSD 0 0 74 173 1 1
BIK EDEM1 0 0 156 155 1 2
BIK BYSL 0 0 134 151 1 1
BIK CASP10 0 0 219 245 1 1
BIK PPP1R15A 0 0 232 231 1 2
BIK TRAF2 0 0 112 167 1 2
BIK TMBIM6 0 0 419 418 1 1
BIK AIG1 113 0 96 182 1 1
BIK LBR 0 0 90 152 1 1
BIK FIS1 0 0 683 683 1 2
BIK NAIP 0 0 188 188 1 1
BIK FAIM3 0 0 124 158 1 1
BIK CASP2 0 0 265 265 1 1
BIK FAIM 0 0 161 161 1 1
BIK MYC 0 0 325 346 1 2
BIK TNF 0 0 218 218 1 2
BIK UBE2D1 270 0 45 281 1 1
BIK ANKRD9 270 0 136 342 1 1
BIK C22orf29 0 0 684 684 1 1
BIK TNFRSF25 0 0 234 250 1 1
BIK GAPDH 0 0 296 296 1 2
BIK CDK10 0 0 56 248 1 1
BIK XIAP 0 0 324 338 1 2
BIK BNIPL 0 0 260 269 1 1
BIK ABL1 0 0 123 174 1 1
BIK MAP2K7 0 0 216 298 1 1
BIK ATF6 0 0 342 342 1 2
BIK CARD8 0 0 157 156 1 1
BIK CASP6 0 0 370 370 1 1
BIK TPD52 0 0 136 151 1 1
BIK FAS 0 0 276 276 1 2
BIK ATF4 0 0 181 181 1 2
BIK AKT1 0 0 325 325 1 2
BIK BCL2L1 879 900 941 999 1 2
BIK IL17RB 0 0 74 177 1 1
BIK UHRF1 0 0 74 168 1 1
BIK EFNB3 0 0 0 297 1 1
BIK NFKB1 0 0 134 188 1 2
BIK ERBB2 0 0 212 212 1 2
BIK MED24 0 0 81 177 1 1
BIK PERP 0 0 143 200 1 1
BIK ANXA5 0 0 370 370 1 2
BIK BBC3 0 0 605 605 1 2
BIK TEF 0 0 193 207 1 1
BIK CARD6 0 0 294 309 1 1
BIK TNFSF8 0 0 275 302 1 1
BIK HSF1 0 0 134 227 1 2
BIK TNFSF9 0 0 90 168 1 1
BIK AIFM1 0 0 171 214 1 1
BIK CAAP1 0 0 157 175 1 1
BIK TENC1 0 0 135 167 1 1
BIK BIRC8 0 0 244 260 1 1
BIK CCNG2 0 0 166 165 1 1
BIK BCL6 0 0 181 181 1 1
BIK BIRC2 0 0 265 274 1 1
BIK KIAA0247 0 0 135 154 1 1
BIK BIRC5 0 0 236 236 1 2
BIK EIF2AK3 0 0 261 261 1 2
BIK NFYB 0 0 134 157 1 1
BIK UBE2C 0 0 66 372 1 1
BIK TP53INP1 0 0 173 187 1 2
BIK CYLC2 0 0 167 167 1 1
BIK TNFRSF1A 0 0 258 258 1 1
BIK BNIP1 0 0 299 333 1 2
BIK BIRC6 0 0 212 222 1 1
BIK PADI1 0 0 294 294 1 1
BIK RNF112 0 0 149 200 1 1
BIK ENDOG 0 0 285 290 1 1
BIK STAT1 0 0 157 156 1 2
BIK BCL2L2-PABPN1 0 0 683 683 1 1
BIK DAP3 0 0 153 500 1 1
BIK CD40LG 0 0 166 165 1 1
BIK TRAF4 0 0 183 208 1 1
BIK PIDD1 0 0 321 321 1 1
BIK CD47 0 0 509 509 1 2
BIK MTOR 0 0 134 176 1 2
BIK IL36B 0 0 49 179 1 1
BIK FOXO3 0 0 212 212 1 2
BIK MFN2 0 0 502 502 1 2
BIK EPHA2 0 0 47 254 1 1
BIK LMTK2 0 0 266 266 1 1
BIK PDCD7 0 0 161 161 1 1
BIK HRAS 0 0 184 183 1 2
BIK CDK2 0 0 170 169 1 2
BIK PRKCD 0 0 218 218 1 2
BIK CDKN1B 0 0 150 169 1 2
BIK TNFRSF1B 0 0 113 174 1 1
BIK PACS2 0 0 142 165 1 1
BIK BNIP3L 0 0 358 374 1 2
BIK FAM92A1 0 0 134 166 1 1
BIK DNM3 0 0 386 386 1 1
BIK VDAC1 0 0 447 447 1 2
BIK HMMR 0 0 45 430 1 1
BIK TOMM20 0 0 134 153 1 2
BIK EIF2S1 0 0 193 193 1 2
BIK BAG3 0 0 243 242 1 2
BIK HIF1A 0 0 213 213 1 2
BIK MT1E 0 0 417 416 1 1
BIK PEX11A 0 0 648 648 1 1
BIK HMOX1 0 0 158 157 1 2
BIK MTFP1 0 0 137 152 1 1
BIK TCHP 0 0 155 154 1 1
BIK HSP90AA1 0 0 211 211 1 2
BIK TRIB3 0 0 134 170 1 2
BIK CPSF1 0 0 260 260 1 1
BIK CASP3 0 0 470 479 1 2
BIK ERBB3 0 0 112 160 1 1
BIK HTRA2 0 0 259 258 1 1
BIK TNFRSF21 0 0 181 181 1 1
BIK TP73 0 0 195 226 1 2
BIK COX4I1 0 0 144 162 1 1
BIK TNFRSF10B 0 0 325 325 1 2
BIK ACTB 0 0 286 286 1 2
BIK BCAR1 0 0 428 428 1 1
BIK DNMT1 0 0 157 156 1 2
BIK MAPK3 0 0 345 345 1 2
BIK CAPN12 0 0 108 171 1 1
BIK DCAF12 0 0 150 173 1 1
BIK BNIP3 94 0 468 506 1 2
BIK GSK3B 0 0 296 296 1 2
BIK CDKN1A 0 0 287 291 1 2
BIK BLK 0 0 128 150 1 1
BIK BCLAF1 0 0 167 167 1 1
BIK CCNG1 0 0 108 163 1 1
BIK LRRC41 0 0 117 212 1 1
BIK BID 0 0 465 479 1 2
BIK RPS27A 270 0 0 270 1 1
BIK CASP4 0 0 320 394 1 2
BIK CDKN2A 0 0 282 282 1 2
BIK BAX 0 0 500 499 1 2
BIK BCL10 0 0 167 183 1 1
BIK BCL2L12 0 0 134 165 1 1
BIK RRM2 0 0 63 224 1 1
BIK LTBR 0 0 142 201 1 1
BIK VCP 270 0 70 292 1 2
BIK FASLG 0 0 348 347 1 1
BIK XAF1 0 0 169 169 1 1
BIK APOL6 0 0 150 267 1 1
BIK CASP14 0 0 210 210 1 1
BIK DNM1 0 0 536 536 1 1
BIK E2F1 0 0 128 151 1 2
BIK HSPA5 0 0 921 921 1 2
BIK IGFBP3 0 0 150 173 1 2
BIK RIPK2 0 0 155 286 1 2
BIK KRAS 0 0 149 180 1 2
BIK DERL1 0 0 162 161 1 1
BIK MSMB 0 0 170 169 1 1
BIK CCNA2 0 0 150 183 1 1
BIK CASP1 0 0 206 260 1 2
BIK BECN1 0 0 297 297 1 2
BIK BRAT1 0 0 96 160 1 1
BIK TUT1 0 0 464 463 1 1
BIK CPSF3 0 0 202 202 1 1
BIK BOK 0 0 690 692 1 1
BIK TRAF3 0 0 125 165 1 2
BIK HIC1 0 0 72 384 1 1
BIK PMAIP1 0 0 782 787 1 2
BIK TNFSF10 0 0 324 323 1 2
BIK DNAJC10 0 0 160 182 1 1
BIK CDC25A 0 0 171 189 1 1
BIK BCL2L15 0 0 284 321 1 1
BIK BCL2L11 417 0 738 857 1 2
BIK SKA3 0 0 73 474 1 1
BIK NOD1 0 0 135 173 1 2
BIK DAPK1 0 0 302 376 1 2
BIK ZNF165 0 0 134 153 1 1
BIK EEFSEC 0 0 170 172 1 1
BIK CDT1 0 0 134 178 1 1
BIK ITPR3 0 0 181 181 1 1
BIK JUN 0 0 260 260 1 2
BIK XBP1 0 0 341 341 1 2
BIK FAM46D 0 0 186 191 1 1
BIK HSPA4 0 0 241 240 1 1
BIK PDIA5 0 0 123 177 1 1
BIK NFYA 0 0 273 287 1 1
BIK IER3 0 0 211 329 1 1
BIK BCL2L14 0 0 361 361 1 1
BIK PEX11B 0 0 641 641 1 1
BIK HSP90B1 0 0 217 217 1 1
BIK ATG5 0 0 193 193 1 2
BIK ESR1 0 0 260 260 1 2
BIK CYCS 0 0 602 606 1 2
BIK GADD45B 0 0 181 211 1 1
BIK CASP9 0 0 505 505 1 2
BIK ITPR1 0 0 180 179 1 2
BIK MCL1 817 0 820 965 1 2
BIK BFAR 0 0 148 234 1 1
BIK SIRT1 0 0 89 230 1 2
BIK PAWR 0 0 157 156 1 1
BIK EGF 0 0 154 153 1 2
BIK TSPYL5 0 0 216 216 1 1
BIK PLAU 0 0 162 161 1 1
BIK RASL11B 0 0 155 229 1 1
BIK SKP2 0 0 82 184 1 2
BIK BTG3 0 0 124 152 1 1
BIK MAPK8 0 0 154 153 1 2
BIK CENPF 0 0 74 383 1 1
BIK DIABLO 0 0 455 455 1 2
BIK SERPINB9 0 0 137 160 1 1
BIK MAP1LC3B 0 0 123 186 1 2
BIK DFFB 0 0 209 209 1 1
BIK ERP27 0 0 100 151 1 1
BIK EHBP1 0 0 248 248 1 1
BIK DAPK3 0 0 93 189 1 2
BIK CSK 0 0 54 150 1 1
BIK CCDC125 0 0 181 237 1 1
BIK INCA1 0 0 125 267 1 1
BIK CUL5 270 0 103 332 1 1
BIK TRADD 0 0 269 284 1 1
BIK BTG2 0 0 143 161 1 1
BIK PCMTD2 0 0 134 227 1 1
BIK DNM2 0 0 540 540 1 1
BIK FATE1 498 0 450 712 1 1
BIK TTLL1 0 0 160 159 1 1
BIK DUSP8 0 0 46 166 1 1
BIK CDK6 0 0 145 150 1 2
BIK HYOU1 0 0 134 154 1 1
BIK HLF 0 0 181 186 1 1
BIK CDH1 0 0 141 171 1 2
BIK BCL2L10 313 0 653 756 1 1
BIK ATM 0 0 187 187 1 2
BIK BCL2L13 0 0 298 299 1 2
BIK THADA 0 0 181 181 1 1
BIK TP53BP2 0 0 203 252 1 2
BIK TIMP3 0 0 112 312 1 1
BIK TNFRSF9 0 0 170 169 1 1
BIK TNFRSF10A 0 0 341 341 1 1
BIK CCNA1 0 0 150 165 1 1
BIK ASB17 270 0 293 555 1 1
BIK RASSF6 0 0 232 248 1 1
BIK AMBP 0 0 197 197 1 1
BIK BIRC3 0 0 359 367 1 1
BIK ANXA8 0 0 155 154 1 1
BIK RNF183 0 0 261 281 1 1
BIK ASAP2 0 0 283 282 1 1
BIK ALB 0 0 169 169 1 2
BIK CASP8 0 0 466 484 1 2
BIK KCNMB2 0 0 175 175 1 1
BIK CASP5 0 0 218 303 1 1
BIK DNM1L 0 0 539 539 1 2
BIK CASP7 0 0 466 467 1 1
BIK PDC 0 0 170 169 1 1
BIK PTEN 0 0 235 235 1 2
BIK RHBDD1 0 0 403 416 1 1
BIK ASB12 0 0 147 301 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0005515 Molecular Function protein binding enables IPI
GO:0008637 Biological Process apoptotic mitochondrial changes involved_in IBA
GO:0006915 Biological Process apoptotic process involved_in TAS
GO:0008584 Biological Process male gonad development involved_in IBA
GO:0031334 Biological Process positive regulation of protein-containing complex assembly involved_in IDA
GO:0090200 Biological Process positive regulation of release of cytochrome c from mitochondria involved_in IDA
GO:0042981 Biological Process regulation of apoptotic process involved_in IDA
GO:0097136 Cellular Component Bcl-2 family protein complex part_of IPI
GO:0012505 Cellular Component endomembrane system located_in IEA
GO:0031966 Cellular Component mitochondrial membrane located_in IEA
Pathways
Name DB ID
DNA damage response (only ATM dependent) (WP710) WikiPathways WP710_r116542
Apoptosis modulation and signaling (WP1772) WikiPathways WP1772_r120736
Transcripts
Accession Version MolecularType Name NCBI Comments
NM_001197 5 mRNA None NC_000022 Reference