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BLM

BLM RecQ like helicase
General Information
Name BLM RecQ like helicase
Alias
  • recQ-like DNA helicase BLM
  • Bloom syndrome RecQ like helicase
  • Bloom syndrome, RecQ helicase-like
  • DNA helicase, RecQ-like type 2
  • bloom syndrome protein
  • recQ protein-like 3
Gene_family RecQ like helicases
organism Homo sapiens
entrez_id 641
location 15q26.1
transcript_count 7
exon_count 24
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez The Bloom syndrome is an autosomal recessive disorder characterized by growth deficiency, microcephaly and immunodeficiency among others. It is caused by homozygous or compound heterozygous mutation in the gene encoding DNA helicase RecQ protein on chromosome 15q26. This Bloom-associated helicase unwinds a variety of DNA substrates including Holliday junction, and is involved in several pathways contributing to the maintenance of genome stability. Identification of pathogenic Bloom variants is required for heterozygote testing in at-risk families. [provided by RefSeq, May 2020]
    Stringdb Bloom syndrome protein; ATP-dependent DNA helicase that unwinds single- and double-stranded DNA in a 3'-5' direction. Participates in DNA replication and repair. Involved in 5'-end resection of DNA during double-strand break (DSB) repair: unwinds DNA and recruits DNA2 which mediates the cleavage of 5'-ssDNA. Negatively regulates sister chromatid exchange (SCE). Stimulates DNA 4-way junction branch migration and DNA Holliday junction dissolution. Binds single-stranded DNA (ssDNA), forked duplex DNA and DNA Holliday junction; RecQ like helicases
    nextProt ATP-dependent DNA helicase that unwinds single- and double-stranded DNA in a 3'-5' direction (PubMed:9388193, PubMed:24816114, PubMed:25901030). Participates in DNA replication and repair (PubMed:12019152, PubMed:21325134, PubMed:23509288). Involved in 5'-end resection of DNA during double-strand break (DSB) repair: unwinds DNA and recruits DNA2 which mediates the cleavage of 5'-ssDNA (PubMed:21325134). Negatively regulates sister chromatid exchange (SCE) (PubMed:25901030). Stimulates DNA 4-way junction branch migration and DNA Holliday junction dissolution (PubMed:25901030). Binds single-stranded DNA (ssDNA), forked duplex DNA and DNA Holliday junction (PubMed:20639533, PubMed:24257077, PubMed:25901030). Recruited by the KHDC3L-OOEP scaffold to DNA replication forks where it is retained by TRIM25 ubiquitination, it thereby promotes the restart of stalled replication forks (By similarity).
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
BLM BioGRID NLE1 GeneID BioGRID Proximity Label-MS
BLM BioGRID RBBP5 GeneID BioGRID Proximity Label-MS
BLM BioGRID MYC GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Proximity Label-MS; Reconstituted Complex
BLM BioGRID SNRNP40 GeneID BioGRID Proximity Label-MS
BLM BioGRID NUP43 GeneID BioGRID Proximity Label-MS
BLM BioGRID ZMYM2 GeneID BioGRID Proximity Label-MS
BLM BioGRID ADARB1 GeneID BioGRID Proximity Label-MS
BLM BioGRID SLX4 GeneID BioGRID Proximity Label-MS
BLM BioGRID H3C3 GeneID BioGRID Proximity Label-MS
BLM BioGRID TIPARP GeneID BioGRID Affinity Capture-MS
BLM BioGRID H3-3A GeneID BioGRID Proximity Label-MS
BLM BioGRID FLT1 GeneID BioGRID Proximity Label-MS
BLM BioGRID RBBP8 GeneID BioGRID Affinity Capture-Western
BLM BioGRID ARL4D GeneID BioGRID Proximity Label-MS
BLM BioGRID RMI1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-fractionation
BLM BioGRID TP53BP1 GeneID BioGRID Affinity Capture-Western; Co-fractionation; Co-localization; Proximity Label-MS; Reconstituted Complex
BLM BioGRID TP53 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Co-localization; Proximity Label-MS; Reconstituted Complex; Two-hybrid
BLM BioGRID PAXIP1 GeneID BioGRID Affinity Capture-MS; Co-fractionation
BLM BioGRID RAD50 GeneID BioGRID Affinity Capture-Western; Co-fractionation; Co-purification
BLM BioGRID RPA3 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-fractionation
BLM BioGRID RPA2 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-fractionation
BLM BioGRID RPA1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity; Co-fractionation; Co-localization; Reconstituted Complex
BLM BioGRID RFC4 GeneID BioGRID Co-fractionation
BLM BioGRID RFC1 GeneID BioGRID Co-fractionation; Co-purification
BLM BioGRID NBN GeneID BioGRID Affinity Capture-Western; Co-fractionation; Co-localization; Co-purification; Reconstituted Complex
BLM BioGRID MSH2 GeneID BioGRID Affinity Capture-Western; Co-fractionation; Co-purification
BLM BioGRID MRE11 GeneID BioGRID Affinity Capture-Western; Co-fractionation; Co-purification
BLM BioGRID MLH1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Co-purification; Far Western; Protein-peptide; Reconstituted Complex; Two-hybrid
BLM BioGRID MSH6 GeneID BioGRID Affinity Capture-Western; Co-fractionation; Co-purification
BLM BioGRID ARL16 GeneID BioGRID Proximity Label-MS
BLM BioGRID PRKN GeneID BioGRID Affinity Capture-MS
BLM BioGRID RNF4 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity
BLM BioGRID RBM3 GeneID BioGRID Affinity Capture-MS
BLM BioGRID PSMB1 GeneID BioGRID Affinity Capture-MS
BLM BioGRID PML GeneID BioGRID Proximity Label-MS
BLM BioGRID MIF GeneID BioGRID Affinity Capture-MS
BLM BioGRID MAP4 GeneID BioGRID Affinity Capture-MS
BLM BioGRID RMI2 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
BLM BioGRID USP37 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
BLM BioGRID RIF1 GeneID BioGRID Affinity Capture-MS
BLM BioGRID H2BC21 GeneID BioGRID Affinity Capture-MS
BLM BioGRID TOP3A GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-localization; Far Western; Reconstituted Complex
BLM BioGRID SRP14 GeneID BioGRID Affinity Capture-MS
BLM BioGRID SRP9 GeneID BioGRID Affinity Capture-MS
BLM BioGRID ATRX GeneID BioGRID Affinity Capture-Western; Proximity Label-MS; Reconstituted Complex
BLM BioGRID NHLH1 GeneID BioGRID Proximity Label-MS
BLM BioGRID MYB GeneID BioGRID Proximity Label-MS
BLM BioGRID KLF16 GeneID BioGRID Proximity Label-MS; Synthetic Growth Defect
BLM BioGRID SIRT6 GeneID BioGRID Affinity Capture-MS
BLM BioGRID Paxip1 GeneID BioGRID Affinity Capture-MS
BLM BioGRID LHX2 GeneID BioGRID Proximity Label-MS
BLM BioGRID LHX1 GeneID BioGRID Proximity Label-MS
BLM BioGRID HNF4A GeneID BioGRID Proximity Label-MS
BLM BioGRID ETV3 GeneID BioGRID Proximity Label-MS
BLM BioGRID DVL2 GeneID BioGRID Affinity Capture-MS
BLM BioGRID KLF9 GeneID BioGRID Proximity Label-MS
BLM BioGRID KLF15 GeneID BioGRID Proximity Label-MS
BLM BioGRID LHX6 GeneID BioGRID Proximity Label-MS
BLM BioGRID KLF12 GeneID BioGRID Proximity Label-MS
BLM BioGRID RPL26L1 GeneID BioGRID Affinity Capture-MS
BLM BioGRID GNL2 GeneID BioGRID Affinity Capture-MS
BLM BioGRID ABT1 GeneID BioGRID Affinity Capture-MS
BLM BioGRID ZBTB44 GeneID BioGRID Affinity Capture-MS
BLM BioGRID APOBEC3C GeneID BioGRID Affinity Capture-MS
BLM BioGRID AIPL1 GeneID BioGRID Affinity Capture-MS
BLM BioGRID KRR1 GeneID BioGRID Affinity Capture-MS
BLM BioGRID RPS16 GeneID BioGRID Affinity Capture-MS
BLM BioGRID RPS13 GeneID BioGRID Affinity Capture-MS
BLM BioGRID RPL27A GeneID BioGRID Affinity Capture-MS
BLM BioGRID RPL19 GeneID BioGRID Affinity Capture-MS
BLM BioGRID MECP2 GeneID BioGRID Affinity Capture-MS
BLM BioGRID ZNF467 GeneID BioGRID Affinity Capture-MS
BLM BioGRID ZNF512 GeneID BioGRID Affinity Capture-MS
BLM BioGRID H2AC17 GeneID BioGRID Affinity Capture-MS
BLM BioGRID MAGEB2 GeneID BioGRID Affinity Capture-MS
BLM BioGRID ANOS1 GeneID BioGRID Affinity Capture-MS
BLM BioGRID H3C1 GeneID BioGRID Proximity Label-MS
BLM BioGRID H2BC8 GeneID BioGRID Proximity Label-MS
BLM BioGRID COIL GeneID BioGRID Proximity Label-MS
BLM BioGRID RPS24 GeneID BioGRID Proximity Label-MS
BLM BioGRID RPS6 GeneID BioGRID Proximity Label-MS
BLM BioGRID RPL31 GeneID BioGRID Proximity Label-MS
BLM BioGRID UTP4 GeneID BioGRID Proximity Label-MS
BLM BioGRID NIFK GeneID BioGRID Proximity Label-MS
BLM BioGRID DHX40 GeneID BioGRID Proximity Label-MS
BLM BioGRID POLR1E GeneID BioGRID Proximity Label-MS
BLM BioGRID TERF2IP GeneID BioGRID Proximity Label-MS
BLM BioGRID ZNF330 GeneID BioGRID Proximity Label-MS
BLM BioGRID ASF1A GeneID BioGRID Proximity Label-MS
BLM BioGRID CBX3 GeneID BioGRID Proximity Label-MS
BLM BioGRID POLR1G GeneID BioGRID Proximity Label-MS
BLM BioGRID NUP50 GeneID BioGRID Proximity Label-MS
BLM BioGRID NOP56 GeneID BioGRID Proximity Label-MS
BLM BioGRID ECT2 GeneID BioGRID Affinity Capture-MS
BLM BioGRID DHX8 GeneID BioGRID Proximity Label-MS
BLM BioGRID CENPA GeneID BioGRID Proximity Label-MS
BLM BioGRID APEX1 GeneID BioGRID Proximity Label-MS
BLM BioGRID PARP1 GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
BLM BioGRID DNAJB1 GeneID BioGRID Proximity Label-MS
BLM BioGRID M GeneID BioGRID Affinity Capture-MS
BLM BioGRID ORF1ab GeneID BioGRID Affinity Capture-MS
BLM BioGRID BRD4 GeneID BioGRID Affinity Capture-MS
BLM BioGRID CHCHD1 GeneID BioGRID Proximity Label-MS
BLM BioGRID KIF20A GeneID BioGRID Affinity Capture-MS
BLM BioGRID KIF14 GeneID BioGRID Affinity Capture-MS
BLM BioGRID RNGTT GeneID BioGRID Proximity Label-MS
BLM BioGRID ESR1 GeneID BioGRID Affinity Capture-MS
BLM BioGRID EXO1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
BLM BioGRID DNA2 GeneID BioGRID Reconstituted Complex
BLM BioGRID FANCD2 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
BLM BioGRID PLEKHA4 GeneID BioGRID Affinity Capture-MS
BLM BioGRID H4C1 GeneID BioGRID Affinity Capture-MS
BLM BioGRID FBXO38 GeneID BioGRID Proximity Label-MS
BLM BioGRID RAD51 GeneID BioGRID Affinity Capture-Western; Co-localization; Far Western; Reconstituted Complex; Synthetic Growth Defect; Two-hybrid
BLM BioGRID XRCC6 GeneID BioGRID Proximity Label-MS
BLM BioGRID TOPBP1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Protein-peptide; Reconstituted Complex
BLM BioGRID FANCA GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
BLM BioGRID SPIDR GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
BLM BioGRID DYNLL1 GeneID BioGRID Affinity Capture-Western; Co-localization
BLM BioGRID FANCM GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
BLM BioGRID ETAA1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
BLM BioGRID MIB1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity
BLM BioGRID FBXW7 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
BLM BioGRID JUN GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
BLM BioGRID BRCA1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-purification; Proximity Label-MS
BLM BioGRID ATM GeneID BioGRID Affinity Capture-Western; Co-purification; Reconstituted Complex
BLM BioGRID RNF8 GeneID BioGRID Biochemical Activity; Reconstituted Complex
BLM BioGRID H2AC4 GeneID BioGRID Affinity Capture-MS
BLM BioGRID XRCC4 GeneID BioGRID Affinity Capture-Western; Co-localization
BLM BioGRID H2AX GeneID BioGRID Affinity Capture-Western; Co-localization
BLM BioGRID SNAI1 GeneID BioGRID Affinity Capture-MS
BLM BioGRID ESR2 GeneID BioGRID Affinity Capture-MS
BLM BioGRID HERC2 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
BLM BioGRID EGLN3 GeneID BioGRID Affinity Capture-MS
BLM BioGRID HIF1AN GeneID BioGRID Affinity Capture-MS
BLM BioGRID ZUP1 GeneID BioGRID Affinity Capture-MS
BLM BioGRID vIRF-4 GeneID BioGRID Affinity Capture-MS
BLM BioGRID RABGGTB GeneID BioGRID Synthetic Lethality
BLM BioGRID MAP2K1 GeneID BioGRID Synthetic Lethality
BLM BioGRID FNTA GeneID BioGRID Synthetic Lethality
BLM BioGRID COX15 GeneID BioGRID Affinity Capture-MS
BLM BioGRID CHEK1 GeneID BioGRID Affinity Capture-Western; Co-localization; Synthetic Lethality
BLM BioGRID CHEK2 GeneID BioGRID Synthetic Lethality
BLM BioGRID TUBA1A GeneID BioGRID Synthetic Lethality
BLM BioGRID WEE1 GeneID BioGRID Synthetic Lethality
BLM BioGRID CENPS GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
BLM BioGRID ADA GeneID BioGRID Synthetic Lethality
BLM BioGRID BRIP1 GeneID BioGRID Affinity Capture-Luminescence; Affinity Capture-Western; Reconstituted Complex
BLM BioGRID MIOS GeneID BioGRID Affinity Capture-MS
BLM BioGRID CEP43 GeneID BioGRID Affinity Capture-MS
BLM BioGRID PDE5A GeneID BioGRID Affinity Capture-MS
BLM BioGRID NEK4 GeneID BioGRID Affinity Capture-MS
BLM BioGRID PPM1H GeneID BioGRID Affinity Capture-MS
BLM BioGRID PHF8 GeneID BioGRID Affinity Capture-MS
BLM BioGRID APBB1 GeneID BioGRID Affinity Capture-Western; Co-localization
BLM BioGRID SNW1 GeneID BioGRID Affinity Capture-MS
BLM BioGRID FOXP1 GeneID BioGRID Affinity Capture-MS
BLM BioGRID Srp72 GeneID BioGRID Affinity Capture-MS
BLM BioGRID Rpl35 GeneID BioGRID Affinity Capture-MS
BLM BioGRID Eif3e GeneID BioGRID Affinity Capture-MS
BLM BioGRID DYNLT1 GeneID BioGRID Proximity Label-MS
BLM BioGRID CASP8 GeneID BioGRID Affinity Capture-MS
BLM BioGRID PSME3IP1 GeneID BioGRID Affinity Capture-MS
BLM BioGRID CORO7 GeneID BioGRID Affinity Capture-MS
BLM BioGRID HPS5 GeneID BioGRID Affinity Capture-MS
BLM BioGRID MCM3AP GeneID BioGRID Affinity Capture-MS
BLM BioGRID TRIM8 GeneID BioGRID Synthetic Growth Defect
BLM BioGRID ACTR5 GeneID BioGRID Synthetic Growth Defect
BLM BioGRID CARS2 GeneID BioGRID Synthetic Growth Defect
BLM BioGRID NDUFA13 GeneID BioGRID Synthetic Growth Defect
BLM BioGRID SNRNP200 GeneID BioGRID Synthetic Growth Defect
BLM BioGRID CILK1 GeneID BioGRID Synthetic Growth Defect
BLM BioGRID TREX2 GeneID BioGRID Synthetic Growth Defect
BLM BioGRID RAD23B GeneID BioGRID Synthetic Growth Defect
BLM BioGRID PSMD1 GeneID BioGRID Synthetic Growth Defect
BLM BioGRID POU3F3 GeneID BioGRID Synthetic Growth Defect
BLM BioGRID ELK4 GeneID BioGRID Synthetic Growth Defect
BLM BioGRID CSNK2B GeneID BioGRID Synthetic Growth Defect
BLM BioGRID CEBPD GeneID BioGRID Synthetic Growth Defect
BLM BioGRID XIAP GeneID BioGRID Synthetic Growth Defect
BLM BioGRID AKR1B1 GeneID BioGRID Synthetic Growth Defect
BLM BioGRID ALDH3B1 GeneID BioGRID Synthetic Growth Defect
BLM BioGRID RAMP1 GeneID BioGRID Synthetic Growth Defect
BLM BioGRID AQR GeneID BioGRID Synthetic Growth Defect
BLM BioGRID MORF4L2 GeneID BioGRID Synthetic Growth Defect
BLM BioGRID RPL14 GeneID BioGRID Synthetic Growth Defect
BLM BioGRID URI1 GeneID BioGRID Synthetic Growth Defect
BLM BioGRID H2AC13 GeneID BioGRID Synthetic Growth Defect
BLM BioGRID VCP GeneID BioGRID Synthetic Growth Defect
BLM BioGRID SUPT5H GeneID BioGRID Synthetic Growth Defect
BLM BioGRID RREB1 GeneID BioGRID Synthetic Growth Defect
BLM BioGRID RPS27A GeneID BioGRID Synthetic Growth Defect
BLM BioGRID RPS19 GeneID BioGRID Synthetic Growth Defect
BLM BioGRID RPS14 GeneID BioGRID Synthetic Growth Defect
BLM BioGRID RPL37 GeneID BioGRID Synthetic Growth Defect
BLM BioGRID RPL23A GeneID BioGRID Synthetic Growth Defect
BLM BioGRID RPL7 GeneID BioGRID Synthetic Growth Defect
BLM BioGRID HES5 GeneID BioGRID Synthetic Growth Defect
BLM BioGRID MMS22L GeneID BioGRID Synthetic Growth Defect
BLM BioGRID TRIM15 GeneID BioGRID Synthetic Growth Defect
BLM BioGRID FAAP100 GeneID BioGRID Affinity Capture-MS
BLM BioGRID SUMO2 GeneID BioGRID Two-hybrid
BLM BioGRID NEK11 GeneID BioGRID Biochemical Activity
BLM BioGRID TRIM49 GeneID BioGRID Biochemical Activity; Reconstituted Complex
BLM BioGRID EGFR GeneID BioGRID Affinity Capture-MS
BLM BioGRID FAN1 GeneID BioGRID Affinity Capture-Western
BLM BioGRID CENPX GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
BLM BioGRID BLM GeneID BioGRID Affinity Capture-MS
BLM BioGRID PWP1 GeneID BioGRID Affinity Capture-MS
BLM BioGRID UPF2 GeneID BioGRID Two-hybrid
BLM BioGRID SUMO1 GeneID BioGRID Two-hybrid
BLM BioGRID UIMC1 GeneID BioGRID Affinity Capture-Western
BLM BioGRID TERF2 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
BLM BioGRID TERF1 GeneID BioGRID Reconstituted Complex
BLM BioGRID MAGOH GeneID BioGRID Affinity Capture-MS
BLM BioGRID EIF4A3 GeneID BioGRID Affinity Capture-MS
BLM BioGRID SF3B2 GeneID BioGRID Affinity Capture-MS
BLM BioGRID TOP2A GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
BLM BioGRID TEP1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
BLM BioGRID HSP90AA1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
BLM BioGRID CAND1 GeneID BioGRID Affinity Capture-MS
BLM BioGRID COPS5 GeneID BioGRID Affinity Capture-MS
BLM BioGRID SIRT7 GeneID BioGRID Affinity Capture-MS
BLM BioGRID Ercc6l GeneID BioGRID Affinity Capture-MS
BLM BioGRID Rmi1 GeneID BioGRID Affinity Capture-MS
BLM BioGRID Top3a GeneID BioGRID Affinity Capture-MS
BLM BioGRID FANCG GeneID BioGRID Affinity Capture-Western
BLM BioGRID ATR GeneID BioGRID Affinity Capture-Western; Biochemical Activity
BLM BioGRID MCRS1 GeneID BioGRID Two-hybrid
BLM BioGRID UBE2I GeneID BioGRID Affinity Capture-Western; Two-hybrid
BLM BioGRID SYN1 GeneID BioGRID Two-hybrid
BLM BioGRID PSMD3 GeneID BioGRID Two-hybrid
BLM BioGRID RRM3 GeneID BioGRID Dosage Rescue
BLM BioGRID SGS1 GeneID BioGRID Dosage Rescue
BLM BioGRID FEN1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
BLM BioGRID RAD50 GeneID BioGRID Dosage Rescue
BLM BioGRID MLH1 GeneID BioGRID Protein-peptide; Two-hybrid
BLM Protein TP53BP1 GeneID HPRD
BLM Protein WRN GeneID HPRD
BLM Protein CHEK1 GeneID HPRD
BLM Protein SUMO2 GeneID HPRD
BLM Protein RAD51D GeneID HPRD
BLM Protein SUMO3 GeneID HPRD
BLM Protein TERF2 GeneID HPRD
BLM Protein CHAF1A GeneID HPRD
BLM Protein TOP3A GeneID HPRD
BLM Protein TERF1 GeneID HPRD
BLM Protein CASP3 GeneID HPRD
BLM Protein FEN1 GeneID HPRD
BLM Protein SMC1A GeneID HPRD
BLM Protein FANCD2 GeneID HPRD
BLM Protein TP53 GeneID HPRD
BLM Protein RPA1 GeneID HPRD
BLM Protein RAD51 GeneID HPRD
BLM Protein MX1 GeneID HPRD
BLM Protein MLH1 GeneID HPRD
BLM BioGRID WRN GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
BLM BioGRID RAD51D GeneID BioGRID Affinity Capture-Western; Far Western; Reconstituted Complex; Two-hybrid
BLM BioGRID CHAF1A GeneID BioGRID Affinity Capture-Western; Far Western; Two-hybrid
BLM BioGRID XRCC2 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
BLM BioGRID CASP3 GeneID BioGRID Biochemical Activity
BLM BioGRID MX1 GeneID BioGRID Two-hybrid
BLM Protein TP53 GeneID BIND BLM interacts with p53. This interaction was modeled on a demonstrated interaction between BLM and p53 both from African green monkey.
BLM Protein TOP3A GeneID BIND BLM interacts with Top3A (Topo III-alpha).
BLM Protein MLH1 GeneID BIND MLH1 interacts with BLM.
BLM Protein WRN GeneID BIND BLM interacts with WRN.
BLM Protein TERF2 GeneID BIND BLM interacts with TRF2.
BLM Protein TOP3A GeneID BIND BLM interacts with Topoisomerase III-alpha.
BLM Protein TP53 GeneID BIND BLM interacts with p53.
BLM Protein TP53 GeneID BIND p53 interacts with BLM.
BLM Protein RAD51 GeneID BIND BLM interacts with RAD51.
StringDB
A B experiments database textmining combined score hadb nhadb
BLM LIG1 0 0 383 704 1 1
BLM SOD3 0 0 0 151 1 1
BLM NEK2 0 0 0 237 1 1
BLM NBN 535 600 467 931 1 1
BLM PSMD14 0 0 0 164 1 1
BLM DDX11 0 0 261 432 1 1
BLM FANCL 0 900 539 954 1 1
BLM SMEK2 0 0 0 168 1 1
BLM FAM175A 0 0 261 272 1 1
BLM PIAS3 0 0 0 487 1 1
BLM CHD3 0 0 74 302 1 1
BLM POLE4 0 900 0 906 1 1
BLM SMG6 0 0 72 165 1 1
BLM KCTD19 0 0 0 198 1 1
BLM POLE3 0 900 0 906 1 1
BLM ENSG00000268361 0 0 0 314 1 1
BLM ERCC6 0 0 161 365 1 1
BLM GIT1 0 0 0 153 1 1
BLM PCNA 0 900 0 963 1 2
BLM NUP160 0 0 58 176 1 1
BLM SMC1B 0 0 203 424 1 1
BLM RAD51D 297 0 150 760 1 1
BLM TP53BP1 687 0 393 987 1 1
BLM CBX1 0 0 306 328 1 1
BLM SMARCA4 0 0 143 479 1 1
BLM SIRT1 0 0 108 563 1 2
BLM HIST1H2AD 0 0 0 165 1 1
BLM IQCA1P1 0 0 0 156 1 1
BLM ORC2 0 0 0 324 1 1
BLM GPR149 0 0 0 171 1 1
BLM CENPQ 0 0 134 328 1 1
BLM RIF1 486 0 280 716 1 1
BLM ATAD2B 0 0 0 150 1 1
BLM HIST1H3C 0 0 71 205 1 1
BLM MSH3 0 0 181 624 1 1
BLM AIPL1 169 0 0 169 1 1
BLM LMNB2 0 0 44 163 1 1
BLM RASAL2 0 0 103 215 1 1
BLM UBA52 0 900 0 900 1 1
BLM GPD2 0 0 0 283 1 1
BLM ERCC6L 766 0 436 919 1 1
BLM UIMC1 270 0 182 404 1 1
BLM LRR1 0 0 0 205 1 1
BLM HIST1H3A 86 0 55 229 1 1
BLM GINS2 0 0 95 380 1 1
BLM SRCAP 0 0 74 343 1 1
BLM PI4KB 0 0 0 284 1 1
BLM UBN1 0 0 122 273 1 1
BLM MCM8 0 0 108 363 1 1
BLM ORC5 0 0 0 163 1 1
BLM PSMB11 0 0 66 269 1 1
BLM RECQL4 0 0 687 423 1 1
BLM PDS5A 0 0 0 220 1 1
BLM CHD4 0 0 46 281 1 1
BLM PSMB7 0 0 0 213 1 1
BLM GMNN 0 0 95 342 1 1
BLM RMI2 872 800 574 990 1 1
BLM NUB1 0 0 0 202 1 1
BLM ATM 674 900 523 997 1 2
BLM POLE2 0 900 181 957 1 1
BLM PWP1 270 0 0 270 1 1
BLM MRE11A 674 600 310 992 1 1
BLM RAD23B 44 0 70 214 1 1
BLM PNKP 0 0 90 364 1 1
BLM POLI 0 0 156 276 1 1
BLM RBL2 0 0 108 192 1 1
BLM HAT1 0 0 90 288 1 1
BLM C8orf82 0 0 0 187 1 1
BLM MEIOB 0 0 53 692 1 1
BLM DTL 0 0 0 680 1 1
BLM NABP2 270 0 141 346 1 1
BLM HIST1H3I 0 0 55 191 1 1
BLM ERCC1 0 900 240 969 1 1
BLM CENPI 0 0 0 223 1 1
BLM FANCF 0 900 645 962 1 1
BLM XRCC5 0 0 374 847 1 1
BLM PHB2 0 0 0 205 1 1
BLM AKAP1 0 0 0 152 1 1
BLM PSMD3 192 0 0 214 1 1
BLM RRM2 0 0 66 428 1 1
BLM PDCD11 0 0 0 207 1 1
BLM HMGB3 0 0 0 151 1 1
BLM CHD8 0 0 0 267 1 1
BLM PI4KA 0 0 0 284 1 1
BLM FBXO5 0 0 0 340 1 1
BLM DHFR 0 0 0 242 1 1
BLM ZRANB3 0 0 124 369 1 1
BLM RACGAP1 0 0 0 324 1 1
BLM HIST3H3 0 900 0 914 1 1
BLM STRA13 913 0 0 913 1 1
BLM DAXX 0 0 294 310 1 1
BLM AICDA 0 0 306 306 1 1
BLM PSMB9 0 0 0 224 1 1
BLM KAT8 0 0 0 231 1 1
BLM VPS29 0 0 0 161 1 1
BLM DTYMK 0 0 0 234 1 1
BLM KIAA1524 0 0 0 184 1 1
BLM POT1 0 900 397 958 1 1
BLM GNA15 0 0 108 245 1 1
BLM POLA2 0 0 0 398 1 1
BLM USP48 0 0 142 219 1 1
BLM HELLS 0 0 91 520 1 1
BLM TIMELESS 0 600 230 979 1 1
BLM ZWILCH 0 0 0 284 1 1
BLM MIS18A 0 0 0 161 1 1
BLM NCAPG 0 0 0 766 1 1
BLM PIK3CB 0 0 0 284 1 1
BLM SKA1 0 0 0 175 1 1
BLM STK38L 0 0 134 164 1 1
BLM WEE1 131 0 112 398 1 1
BLM CDT1 0 0 132 515 1 1
BLM OTC 0 0 0 163 1 1
BLM RFC5 0 600 0 744 1 1
BLM ENSG00000267618 0 0 150 673 1 1
BLM RNF20 0 0 55 260 1 1
BLM SPC25 0 0 0 203 1 1
BLM UBE2E3 0 0 0 164 1 1
BLM NHP2 0 0 134 161 1 1
BLM DDX43 0 0 0 171 1 1
BLM TBPL1 0 0 0 225 1 1
BLM PARP2 0 0 233 624 1 1
BLM DDX31 0 0 0 226 1 1
BLM HIST1H2AH 0 0 0 342 1 1
BLM GAB1 0 0 0 213 1 1
BLM RAD1 0 600 230 836 1 1
BLM TTLL5 0 0 0 160 1 1
BLM DDX24 0 0 45 177 1 1
BLM APLF 0 0 58 235 1 1
BLM E2F1 0 0 54 158 1 2
BLM TOP2B 0 0 0 838 1 1
BLM EIF4A2 0 0 43 157 1 1
BLM HIST1H3J 116 0 55 272 1 1
BLM HIST1H2BN 0 900 0 904 1 1
BLM CHTF18 0 0 0 618 1 1
BLM SMC6 0 0 234 879 1 1
BLM C1orf112 0 0 0 272 1 1
BLM AGO3 0 0 0 235 1 1
BLM NEIL3 0 0 0 392 1 1
BLM NOP10 0 0 140 168 1 1
BLM NCAPD3 0 0 0 210 1 1
BLM PHF14 0 0 0 204 1 1
BLM MMS22L 44 0 0 211 1 1
BLM PDE5A 256 0 0 272 1 1
BLM INO80 0 0 0 351 1 1
BLM TYMS 0 0 75 405 1 1
BLM USP25 0 0 140 231 1 1
BLM POLA1 0 0 193 785 1 1
BLM XAB2 0 0 165 183 1 1
BLM PMS2 0 0 123 541 1 1
BLM EP400NL 0 0 0 320 1 1
BLM DDX56 0 0 0 171 1 1
BLM DROSHA 0 0 0 156 1 1
BLM PSME4 0 0 134 499 1 1
BLM E2F4 0 0 87 244 1 1
BLM CLPP 0 0 74 495 1 1
BLM PARP4 0 0 0 162 1 1
BLM DDX10 0 0 0 179 1 1
BLM WEE2 0 0 0 255 1 1
BLM FAN1 270 0 0 467 1 1
BLM SUMO1 192 0 207 567 1 1
BLM CDK18 0 0 0 386 1 1
BLM DIS3 0 0 66 152 1 1
BLM PIK3C2A 0 0 0 286 1 1
BLM DDX59 0 0 0 156 1 1
BLM DDB1 0 0 81 217 1 1
BLM TDRD12 0 0 0 171 1 1
BLM MAGOH 272 0 0 297 1 1
BLM MCIDAS 0 0 0 153 1 1
BLM RTEL1 0 900 503 971 1 1
BLM DDX20 0 0 0 196 1 1
BLM ZGRF1 0 0 0 288 1 1
BLM USP7 0 0 74 151 1 1
BLM TEP1 270 0 0 270 1 1
BLM ENSG00000259316 0 0 61 156 1 1
BLM PURG 0 0 0 152 1 1
BLM ZWINT 0 0 0 337 1 1
BLM ENSG00000279928 0 0 0 221 1 1
BLM TRUB2 0 0 0 160 1 1
BLM ZNF112 0 0 228 406 1 1
BLM PRIM2 0 0 96 486 1 1
BLM H2AFJ 0 0 0 296 1 1
BLM YTHDC2 0 0 0 301 1 1
BLM HIST1H2BJ 0 900 0 901 1 1
BLM DDX39B 0 0 0 207 1 1
BLM C1orf53 0 0 0 156 1 1
BLM HMMR 0 0 0 575 1 1
BLM MCRS1 192 0 0 356 1 1
BLM HARS2 0 0 81 494 1 1
BLM ORC6 0 0 0 229 1 1
BLM BIRC6 0 0 0 168 1 1
BLM GMPS 0 0 0 186 1 1
BLM UTP20 0 0 0 154 1 1
BLM CDKN3 0 0 57 333 1 1
BLM TRUB1 0 0 0 170 1 1
BLM TERF2IP 0 900 0 904 1 1
BLM POLB 0 0 170 221 1 1
BLM IGHMBP2 0 0 0 263 1 1
BLM ACIN1 0 0 0 174 1 1
BLM CRY1 0 0 0 219 1 1
BLM LRP8 0 0 0 150 1 1
BLM RAD54L2 0 0 0 255 1 1
BLM STIL 0 0 0 278 1 1
BLM PKMYT1 0 0 90 545 1 1
BLM CCNO 0 0 0 175 1 1
BLM ADA 187 0 0 252 1 1
BLM CRAT 0 0 0 179 1 1
BLM DKC1 0 0 180 312 1 1
BLM ASCC3 0 0 0 219 1 1
BLM UBE2I 270 900 193 976 1 1
BLM PSPC1 0 0 52 313 1 1
BLM RNF170 0 0 0 416 1 1
BLM FAM192A 246 0 0 245 1 1
BLM TACC3 0 0 0 210 1 1
BLM HIST2H2BE 0 900 69 907 1 1
BLM PRKDC 0 0 289 501 1 2
BLM CCNB1IP1 0 0 68 203 1 1
BLM PAK6 0 0 0 177 1 1
BLM DMTF1 0 0 0 175 1 1
BLM MCMBP 0 0 0 255 1 1
BLM PIK3C2B 0 0 0 284 1 1
BLM L3MBTL2 0 0 67 159 1 1
BLM TOPBP1 486 600 406 967 1 1
BLM DDX23 0 0 0 187 1 1
BLM GINS3 0 0 0 214 1 1
BLM NSMCE2 0 0 181 648 1 1
BLM MCM10 0 0 193 890 1 1
BLM SSBP1 0 0 54 365 1 1
BLM EXD2 0 0 61 290 1 1
BLM SLX1B 0 0 299 898 1 1
BLM NHEJ1 0 0 167 167 1 1
BLM TTLL2 0 0 0 160 1 1
BLM SNRPA1 0 0 0 155 1 1
BLM CCNE1 0 0 57 226 1 1
BLM FANCI 0 0 352 789 1 1
BLM CENPK 0 0 0 340 1 1
BLM NDC80 0 0 0 575 1 1
BLM UBB 0 900 0 900 1 1
BLM SYCP3 0 0 155 169 1 1
BLM ERCC6L2 0 0 0 274 1 1
BLM TUBA1A 130 0 0 150 1 1
BLM HELZ 0 0 0 225 1 1
BLM E2F8 0 0 96 348 1 1
BLM CLCNKA 0 0 0 205 1 1
BLM AHCY 0 0 56 235 1 1
BLM KIF23 0 0 0 377 1 1
BLM SHPRH 0 0 57 460 1 1
BLM MUTYH 0 0 94 285 1 1
BLM DDX3X 0 0 73 309 1 1
BLM RPUSD3 0 0 0 158 1 1
BLM CENPH 0 0 0 243 1 1
BLM C11orf30 0 0 0 303 1 1
BLM LIG4 0 0 296 784 1 1
BLM CDK12 0 0 57 171 1 1
BLM TIPIN 0 600 138 974 1 1
BLM HERC2 270 0 0 291 1 1
BLM DDX51 0 0 0 187 1 1
BLM ITPA 0 0 0 247 1 1
BLM C11orf85 0 0 260 296 1 1
BLM MUS81 0 900 504 998 1 1
BLM BRIP1 486 900 322 981 1 1
BLM SGOL2 0 0 0 239 1 1
BLM KNSTRN 0 0 0 177 1 1
BLM TREX1 0 0 0 185 1 1
BLM SUV39H2 0 0 0 320 1 1
BLM HIST1H3H 0 0 55 191 1 1
BLM PEX10 0 0 0 167 1 1
BLM CUL4B 0 0 0 201 1 1
BLM PRDX2 0 0 0 261 1 1
BLM PLEKHA4 270 0 0 270 1 1
BLM GINS4 0 0 0 183 1 1
BLM CDK17 0 0 0 386 1 1
BLM GEN1 0 900 279 960 1 1
BLM PRDX4 0 0 0 261 1 1
BLM GAB4 0 0 0 213 1 1
BLM SAMD1 0 0 0 231 1 1
BLM BHLHE40 0 900 0 900 1 1
BLM CENPF 0 0 46 468 1 1
BLM PHF8 270 0 0 303 1 1
BLM DONSON 0 0 0 261 1 1
BLM XRCC1 0 0 195 424 1 1
BLM HIST1H2AA 0 0 0 308 1 1
BLM EEPD1 0 0 154 290 1 1
BLM XPNPEP2 0 0 74 171 1 1
BLM H2AFY2 0 0 0 214 1 1
BLM PDSS1 0 0 0 173 1 1
BLM CENPW 0 0 0 156 1 1
BLM CHD5 0 0 0 277 1 1
BLM NUP133 0 0 0 226 1 1
BLM HIST3H2A 0 0 0 296 1 1
BLM RABGGTB 128 0 55 194 1 1
BLM CHAT 0 0 0 179 1 1
BLM DDX1 0 0 126 269 1 1
BLM TDP1 0 0 108 397 1 1
BLM SMARCA2 0 0 179 501 1 1
BLM FIGN 0 0 0 156 1 1
BLM DICER1 0 0 66 449 1 1
BLM SENP1 0 0 0 168 1 1
BLM DEPDC1 0 0 0 264 1 1
BLM C17orf70 913 900 0 990 1 1
BLM CDC6 0 0 163 547 1 1
BLM CLSPN 0 600 325 848 1 1
BLM FAM83D 0 0 0 154 1 1
BLM PAICS 0 0 0 248 1 1
BLM DHX36 0 0 194 271 1 1
BLM CRY2 0 0 0 219 1 1
BLM RAPH1 0 0 0 213 1 1
BLM SLBP 0 0 70 202 1 1
BLM REC8 0 0 108 164 1 1
BLM SPIDR 270 600 0 704 1 1
BLM CHD1 0 0 46 289 1 1
BLM SH3PXD2B 0 0 0 284 1 1
BLM EXOSC8 0 0 0 159 1 1
BLM DSCC1 0 0 108 467 1 1
BLM CSNK1D 0 0 0 670 1 1
BLM EIF4A1 0 0 0 199 1 1
BLM BAIAP3 0 0 0 189 1 1
BLM ERCC4 0 900 112 986 1 1
BLM H3F3B 0 0 95 226 1 1
BLM ARL6IP4 0 0 60 552 1 1
BLM XRCC4 270 0 320 496 1 1
BLM MIOS 256 0 0 261 1 1
BLM CDK16 0 0 0 386 1 1
BLM BUB1B 0 0 127 667 1 1
BLM MB21D1 0 0 73 284 1 1
BLM SH3PXD2A 0 0 0 284 1 1
BLM HEATR1 0 0 0 167 1 1
BLM SYCP1 0 0 171 171 1 1
BLM DUT 0 0 0 152 1 1
BLM HIST1H2BO 0 900 0 907 1 1
BLM SIRT6 0 0 397 503 1 2
BLM SYN1 192 0 0 192 1 1
BLM AURKA 0 0 95 547 1 2
BLM HIST1H3D 0 0 71 205 1 1
BLM NUP93 0 0 0 153 1 1
BLM RAD51AP1 0 600 113 834 1 1
BLM CDCA7 0 0 162 366 1 1
BLM ECT2 0 0 0 195 1 1
BLM POLN 0 0 73 262 1 1
BLM SUV420H2 0 0 47 160 1 1
BLM DEPDC1B 0 0 0 312 1 1
BLM TINF2 0 900 324 931 1 1
BLM CCNB2 0 0 49 587 1 1
BLM AUNIP 0 0 0 300 1 1
BLM RNF8 487 0 171 587 1 1
BLM UMPS 0 0 0 463 1 1
BLM SENP6 0 0 0 388 1 1
BLM YEATS2 0 0 0 159 1 1
BLM H2AFB1 0 0 0 165 1 1
BLM COBLL1 0 0 0 213 1 1
BLM SF3B2 270 0 0 312 1 1
BLM DMC1 0 900 108 961 1 1
BLM WDR48 0 0 0 169 1 1
BLM ABCA4 0 0 0 190 1 1
BLM CNTD1 0 0 67 440 1 1
BLM RFC4 0 600 437 881 1 1
BLM SP100 0 0 181 190 1 1
BLM STK11IP 0 0 174 406 1 1
BLM E2F7 0 0 55 295 1 1
BLM HIST2H2AA3 0 0 172 392 1 1
BLM TEN1 0 0 247 246 1 1
BLM UFD1L 0 0 0 159 1 1
BLM DDX4 0 0 0 304 1 1
BLM HSP90AA1 270 0 0 294 1 2
BLM NIPBL 0 0 0 200 1 1
BLM PRLH 0 0 95 157 1 1
BLM DDIAS 0 0 0 188 1 1
BLM CUL4A 0 0 64 218 1 1
BLM RAD9B 0 600 0 774 1 1
BLM PLD6 0 0 113 151 1 1
BLM MTHFD1 0 0 0 175 1 1
BLM TTF2 0 0 0 371 1 1
BLM YEATS4 0 0 0 213 1 1
BLM EPRS 0 0 54 205 1 1
BLM HIST2H2AA 0 0 172 392 1 1
BLM ENSG00000137843 0 0 0 177 1 1
BLM NCAPG2 0 0 0 350 1 1
BLM RNGTT 297 0 0 297 1 1
BLM UBE2E1 0 0 0 164 1 1
BLM PIK3CG 0 0 0 284 1 1
BLM NUP107 0 0 49 280 1 1
BLM TK1 0 0 57 216 1 1
BLM CCNA2 0 0 85 621 1 1
BLM JUN 486 0 55 493 1 2
BLM ASF1A 0 0 103 509 1 1
BLM ASF1B 0 0 125 614 1 1
BLM SKA3 0 0 0 295 1 1
BLM NTHL1 0 0 0 292 1 1
BLM SMC1A 213 0 501 709 1 1
BLM SMC3 0 0 45 391 1 1
BLM CETN2 0 0 62 186 1 1
BLM KPNA2 0 0 0 187 1 1
BLM CDC25C 0 0 96 342 1 2
BLM SOD1 0 0 0 187 1 2
BLM CENPE 0 0 95 406 1 1
BLM HIST1H2AM 0 0 0 328 1 1
BLM MCM3AP 151 0 0 220 1 1
BLM H3F3C 0 0 0 179 1 1
BLM CTSF 0 0 81 193 1 1
BLM DCLRE1C 0 0 0 178 1 1
BLM INSIG2 0 0 42 265 1 1
BLM CEP55 0 0 0 562 1 1
BLM ARHGAP11A 0 0 0 338 1 1
BLM SKA2 0 0 0 153 1 1
BLM QRSL1 0 0 0 159 1 1
BLM HIST1H2BK 0 900 0 901 1 1
BLM ZBTB7A 0 0 74 154 1 1
BLM APBB1 270 0 67 289 1 1
BLM SIRT2 0 0 47 206 1 2
BLM TEF 0 0 74 154 1 1
BLM RPA3 822 600 205 944 1 1
BLM TREX2 44 0 325 578 1 1
BLM POLR2A 0 0 0 212 1 1
BLM ZNFX1 0 0 0 225 1 1
BLM HIST2H2AC 0 0 173 392 1 1
BLM DHX9 0 0 123 221 1 1
BLM DBF4 0 0 103 391 1 1
BLM GSG2 0 0 0 323 1 1
BLM BIVM-ERCC5 0 0 0 750 1 1
BLM UBE2D3 0 0 0 197 1 1
BLM MOV10 0 0 0 225 1 1
BLM CKAP5 0 0 0 448 1 1
BLM TERF2 675 900 438 980 1 1
BLM SMG1 0 0 74 313 1 1
BLM POLD2 0 900 0 935 1 1
BLM RHNO1 0 600 112 648 1 1
BLM PML 0 0 150 159 1 2
BLM ESPL1 0 0 0 408 1 1
BLM PLK4 0 0 54 528 1 1
BLM KAT6A 0 0 0 235 1 1
BLM C19orf40 0 900 384 954 1 1
BLM PARPBP 0 0 0 219 1 1
BLM BUB1 0 0 49 726 1 1
BLM PIGP 0 0 0 200 1 1
BLM FANCB 0 900 120 929 1 1
BLM NUSAP1 0 0 0 565 1 1
BLM POLH 0 900 104 944 1 1
BLM ORC1 0 0 0 484 1 1
BLM PMM1 0 0 0 239 1 1
BLM PNPT1 0 0 0 160 1 1
BLM SMC2 0 0 43 460 1 1
BLM MSH6 535 0 398 972 1 1
BLM TRIM49 270 0 0 278 1 1
BLM SUMO2 476 900 245 982 1 1
BLM DDX28 0 0 0 171 1 1
BLM DARS2 0 0 0 182 1 1
BLM MED6 0 0 0 177 1 1
BLM UBE2G1 0 0 0 157 1 1
BLM HPS5 218 0 0 238 1 1
BLM VRK1 0 0 0 364 1 1
BLM MAEL 0 0 95 568 1 1
BLM RAD51C 0 600 288 837 1 1
BLM TROAP 0 0 0 312 1 1
BLM PDS5B 0 0 0 200 1 1
BLM PIK3C3 0 0 0 285 1 2
BLM ACAN 0 0 0 155 1 1
BLM PPP4C 0 0 95 282 1 1
BLM UBN2 0 0 0 206 1 1
BLM TCF20 0 0 0 154 1 1
BLM CHD1L 0 0 0 255 1 1
BLM SRSF9 0 0 0 174 1 1
BLM RAD23A 0 0 0 187 1 1
BLM RAD51 870 600 602 999 1 2
BLM SGOL1 0 0 47 190 1 1
BLM MTOR 0 0 49 290 1 2
BLM E2F2 0 0 66 194 1 1
BLM HIST1H4F 270 0 90 328 1 1
BLM KAT6B 0 0 0 247 1 1
BLM APBB1IP 0 0 0 213 1 1
BLM CHAF1B 0 0 172 479 1 1
BLM FGFR1OP 256 0 0 257 1 1
BLM RNF10 0 0 0 416 1 1
BLM NOA1 0 0 0 199 1 1
BLM NUP37 0 0 0 216 1 1
BLM VRK3 0 0 0 158 1 1
BLM RBL1 0 0 54 213 1 1
BLM MARS 0 0 0 151 1 1
BLM NSMCE4A 0 0 0 453 1 1
BLM DLGAP5 0 0 0 623 1 1
BLM TP53 871 900 459 992 1 2
BLM MDM2 0 0 123 156 1 2
BLM FAM64A 0 0 46 273 1 1
BLM BTAF1 0 0 0 209 1 1
BLM INSIG1 0 0 0 265 1 1
BLM RFC3 0 600 0 781 1 1
BLM FANCC 0 900 611 959 1 1
BLM ERGIC2 0 0 155 178 1 1
BLM SFPQ 0 0 0 166 1 1
BLM HJURP 0 0 0 556 1 1
BLM FMN2 0 0 0 153 1 1
BLM CENPA 0 0 54 352 1 1
BLM ZNF618 0 0 166 305 1 1
BLM RAD9A 0 600 277 829 1 1
BLM MELK 0 0 0 356 1 1
BLM NEK11 270 0 0 383 1 1
BLM BOD1L1 0 0 180 347 1 1
BLM CCNI 0 0 0 175 1 1
BLM RAD18 0 0 184 860 1 1
BLM TOP1 0 0 341 905 1 1
BLM RNF212B 0 0 0 531 1 1
BLM TBC1D31 0 0 0 155 1 1
BLM CENPS-CORT 0 0 0 212 1 1
BLM MTFMT 0 0 0 173 1 1
BLM CASC5 0 0 0 294 1 1
BLM DBF4B 0 0 0 270 1 1
BLM CKS2 0 0 90 253 1 1
BLM DDX49 0 0 0 191 1 1
BLM HLTF 0 0 124 861 1 1
BLM HORMAD1 0 0 0 161 1 1
BLM CBX5 0 0 291 315 1 1
BLM PURA 0 0 0 219 1 1
BLM DSN1 0 0 0 204 1 1
BLM MAD2L1 0 0 73 639 1 1
BLM HIST1H2AE 270 0 0 364 1 1
BLM HNRNPU 0 0 159 205 1 1
BLM BRCA1 704 600 466 950 1 2
BLM TOP2A 270 0 184 931 1 1
BLM ZNF367 0 0 0 150 1 1
BLM REV1 0 0 194 506 1 1
BLM BOLA2 0 0 0 297 1 1
BLM YRDC 0 0 0 167 1 1
BLM CDC5L 0 0 81 398 1 1
BLM PRR11 0 0 0 231 1 1
BLM KIF20B 0 0 0 319 1 1
BLM RFC1 291 900 0 975 1 1
BLM DDX50 0 0 0 156 1 1
BLM DDX39A 0 0 0 218 1 1
BLM XRCC3 0 600 387 992 1 1
BLM HIST1H2AG 0 0 0 308 1 1
BLM HIST1H2BH 0 900 0 907 1 1
BLM SLC12A9 0 0 0 315 1 1
BLM MDC1 0 0 293 758 1 1
BLM PBK 0 0 0 351 1 1
BLM FBXO24 0 0 74 225 1 1
BLM RAD52 0 600 520 991 1 1
BLM PLK3 0 0 0 390 1 1
BLM RAD51B 0 600 261 850 1 1
BLM SNX5 0 0 353 384 1 1
BLM NONO 0 0 95 197 1 1
BLM CDC45 0 0 309 886 1 1
BLM MCM2 0 0 241 708 1 1
BLM TERT 0 0 167 759 1 2
BLM PSMC3IP 0 0 0 180 1 1
BLM UBC 0 900 0 900 1 2
BLM SASS6 0 0 0 192 1 1
BLM SARS 0 0 0 164 1 1
BLM TTK 0 0 104 604 1 1
BLM FOXN2 0 0 167 167 1 1
BLM MLLT1 0 0 0 159 1 1
BLM CTPS1 0 0 0 157 1 1
BLM ENSG00000279765 0 0 0 267 1 1
BLM HIST2H3A 0 0 0 179 1 1
BLM SMEK1 0 0 0 156 1 1
BLM OBFC1 0 0 252 514 1 1
BLM MYBL2 0 0 0 264 1 1
BLM MIB1 487 0 0 495 1 1
BLM LMNB1 0 0 301 409 1 1
BLM SLX4 0 900 337 930 1 1
BLM AIRE 0 0 74 434 1 1
BLM POLD1 0 900 174 971 1 1
BLM H2AFY 0 0 0 214 1 1
BLM PURB 0 0 0 152 1 1
BLM UBE2D2 0 0 0 197 1 1
BLM MSH2 535 0 360 930 1 1
BLM CHD2 0 0 0 293 1 1
BLM H2BFS 0 900 0 901 1 1
BLM HIST1H3B 0 0 55 222 1 1
BLM KAT5 0 600 103 713 1 1
BLM MRPL45 0 0 0 181 1 1
BLM MASTL 0 0 0 214 1 1
BLM RFWD3 0 0 0 353 1 1
BLM RPUSD2 0 0 0 159 1 1
BLM PRIM1 0 0 218 695 1 1
BLM HIST1H2AK 0 0 0 308 1 1
BLM CHFR 0 0 43 155 1 1
BLM E2F3 0 0 61 190 1 1
BLM PTTG1 0 0 0 317 1 1
BLM TERF1 297 900 392 955 1 1
BLM AGO1 0 0 0 235 1 1
BLM E2F5 0 0 75 343 1 1
BLM TELO2 0 0 357 387 1 1
BLM RECQL5 0 0 674 415 1 1
BLM TRAIP 0 0 0 174 1 1
BLM ASPM 0 0 0 615 1 1
BLM UBE2S 0 0 83 200 1 1
BLM PSMB10 0 0 54 312 1 1
BLM ST5 0 0 107 307 1 1
BLM APITD1 992 900 0 999 1 1
BLM REV3L 0 0 123 649 1 1
BLM UNG 0 0 172 364 1 1
BLM PRDM9 0 0 167 180 1 1
BLM UBE2O 0 0 0 177 1 1
BLM TXNDC12 0 0 112 286 1 1
BLM MRPL36 0 0 134 264 1 1
BLM RPS27A 44 900 0 901 1 1
BLM CCNG1 0 0 0 175 1 1
BLM ORC4 0 0 163 312 1 1
BLM DDX42 0 0 46 171 1 1
BLM POC1A 0 0 0 154 1 1
BLM ERCC5 0 0 81 761 1 1
BLM ENSG00000258838 0 0 85 307 1 1
BLM PIK3CD 0 0 0 284 1 1
BLM CENPN 0 0 0 269 1 1
BLM MLLT3 0 0 0 159 1 1
BLM MBD4 0 0 131 281 1 1
BLM DDX6 0 0 0 169 1 1
BLM CASP3 270 0 51 277 1 2
BLM UPF2 177 0 0 221 1 1
BLM UBE2V1 0 0 0 382 1 1
BLM HIST1H2AL 0 0 0 308 1 1
BLM CDCA2 0 0 0 270 1 1
BLM BRCA2 0 800 467 933 1 1
BLM PSMB6 0 0 81 189 1 1
BLM NCAPH 0 0 0 440 1 1
BLM NUF2 0 0 0 335 1 1
BLM NEK4 178 0 0 198 1 1
BLM RAD21 0 0 50 155 1 1
BLM PPME1 0 0 93 168 1 1
BLM ASZ1 0 0 154 193 1 1
BLM SMARCA1 0 0 126 321 1 1
BLM C17orf64 0 0 0 267 1 1
BLM UBA2 0 0 90 267 1 1
BLM PHF21B 0 0 0 271 1 1
BLM DDX60L 0 0 0 367 1 1
BLM PIAS1 0 0 93 514 1 1
BLM NCAPD2 0 0 0 353 1 1
BLM CHAF1A 297 0 180 630 1 1
BLM MLH1 872 650 397 995 1 1
BLM CPSF3 0 0 0 155 1 1
BLM CYB5R4 0 0 0 207 1 1
BLM AKIRIN2 0 0 0 183 1 1
BLM HIST1H2BB 0 900 0 904 1 1
BLM GIT2 0 0 81 292 1 1
BLM CHD9 0 0 61 282 1 1
BLM RBBP8 0 600 505 805 1 1
BLM MSH4 0 600 280 901 1 1
BLM CDC25A 0 0 306 473 1 1
BLM TMPO 0 0 0 194 1 1
BLM PAK4 0 0 0 177 1 1
BLM PPAT 0 0 0 236 1 1
BLM MCM6 0 0 163 524 1 1
BLM MTFR2 0 0 0 265 1 1
BLM TRDMT1 0 0 0 179 1 1
BLM ANKRD32 0 0 0 509 1 1
BLM NUP155 0 0 0 294 1 1
BLM FANCG 270 900 609 973 1 1
BLM HNRNPC 0 0 112 196 1 1
BLM SNRNP200 44 0 0 180 1 1
BLM CORO1C 0 0 92 165 1 1
BLM ANAPC10 0 0 95 309 1 1
BLM TTLL8 0 0 0 160 1 1
BLM UPF1 0 0 66 259 1 1
BLM HIST1H3E 0 0 71 205 1 1
BLM KDM2B 0 0 358 374 1 1
BLM TOP1MT 0 0 0 862 1 1
BLM CDK15 0 0 0 386 1 1
BLM CCNE2 0 0 74 259 1 1
BLM FANCD2 486 0 607 904 1 1
BLM NSMCE1 0 0 0 375 1 1
BLM HIST1H3G 0 0 55 208 1 1
BLM UBE2E2 0 0 0 164 1 1
BLM PRDX3 0 0 0 261 1 1
BLM BIRC5 0 0 0 341 1 2
BLM SIRT4 0 0 0 201 1 1
BLM MCM9 0 0 66 298 1 1
BLM OIP5 0 0 0 610 1 1
BLM CASC1 0 0 167 185 1 1
BLM SF1 0 0 0 216 1 1
BLM CCNG2 0 0 0 175 1 1
BLM CETN1 0 0 0 167 1 1
BLM PIKFYVE 0 0 0 174 1 2
BLM SMC4 0 0 45 504 1 1
BLM WDHD1 0 0 150 785 1 1
BLM HUS1 0 600 296 862 1 1
BLM EIF2B2 0 0 66 169 1 1
BLM PPP2R4 0 0 46 182 1 1
BLM HIST2H2AB 0 0 0 308 1 1
BLM UBR2 0 0 0 220 1 1
BLM CTC1 0 0 212 223 1 1
BLM STAG3 0 0 112 189 1 1
BLM MKI67 0 0 0 381 1 2
BLM ARPC4-TTLL3 0 0 0 166 1 1
BLM SETX 0 0 108 377 1 1
BLM ENSG00000267173 0 0 0 262 1 1
BLM HIST1H2BA 0 900 0 901 1 1
BLM ALKBH8 0 0 0 215 1 1
BLM RRM1 0 0 137 423 1 1
BLM KNTC1 0 0 0 360 1 1
BLM ENSG00000255767 0 0 0 294 1 1
BLM TRRAP 0 0 0 286 1 1
BLM ACD 0 900 276 924 1 2
BLM OTP 0 0 0 219 1 1
BLM NARFL 0 0 261 322 1 1
BLM CDCA8 0 0 0 565 1 1
BLM BOLA2-SMG1P6 0 0 0 284 1 1
BLM TTLL3 0 0 0 160 1 1
BLM LIN28B 0 0 0 164 1 1
BLM POLD3 0 900 211 954 1 1
BLM MOV10L1 0 0 0 226 1 1
BLM USP1 0 0 94 217 1 1
BLM PIAS4 0 0 72 503 1 1
BLM IQGAP3 0 0 0 165 1 1
BLM CKAP2 0 0 0 232 1 1
BLM COASY 0 0 0 202 1 1
BLM UBE2C 0 0 0 397 1 1
BLM HFM1 0 0 150 513 1 1
BLM TEN1-CDK3 0 0 0 386 1 1
BLM MCM3 0 0 90 502 1 1
BLM ATAD5 0 0 120 824 1 1
BLM CCNI2 0 0 0 175 1 1
BLM C10orf54 0 0 88 285 1 1
BLM RNASEH1 0 0 299 489 1 1
BLM PINX1 0 0 306 324 1 1
BLM XRCC2 270 600 306 830 1 1
BLM ATR 270 600 400 995 1 2
BLM PAXIP1 270 0 141 973 1 1
BLM PRPF19 0 0 112 190 1 1
BLM DDB2 0 0 253 345 1 1
BLM CDK1 0 0 270 765 1 2
BLM AHCYL2 0 0 0 189 1 1
BLM TTBK1 0 0 0 158 1 1
BLM C10orf2 0 0 122 475 1 1
BLM DDX60 0 0 0 367 1 1
BLM SESN1 0 0 150 243 1 1
BLM MCM7 0 0 230 540 1 1
BLM KIF14 270 0 0 495 1 1
BLM C15orf43 0 0 202 260 1 1
BLM HIST1H3F 0 0 55 191 1 1
BLM EID3 0 0 0 453 1 1
BLM HELZ2 0 0 0 229 1 1
BLM HUS1B 0 0 0 223 1 1
BLM BARD1 0 600 233 741 1 1
BLM DDX5 0 0 0 156 1 1
BLM LIN28A 0 0 0 167 1 1
BLM ACOT13 0 0 0 150 1 1
BLM MAD2L2 0 0 62 364 1 1
BLM EXOSC7 0 0 0 155 1 1
BLM TMEM189-UBE2V1 0 0 0 378 1 1
BLM KIF22 0 0 0 200 1 1
BLM RPA1 890 600 306 997 1 1
BLM RAD54B 0 0 236 872 1 1
BLM AHCTF1 0 0 0 153 1 1
BLM DDX46 0 0 0 210 1 1
BLM DIAPH3 0 0 0 206 1 1
BLM ALDH18A1 0 0 0 395 1 1
BLM DDX17 0 0 0 178 1 1
BLM GH1 0 0 306 306 1 1
BLM ERCC3 0 0 96 649 1 1
BLM TTL 0 0 0 160 1 1
BLM TPX2 0 0 0 555 1 1
BLM CDK3 0 0 0 386 1 1
BLM FMR1 0 0 74 217 1 1
BLM NUP205 0 0 0 203 1 1
BLM PRC1 0 0 0 562 1 1
BLM RNF4 270 0 226 518 1 1
BLM PIAS2 0 0 97 517 1 1
BLM FBXO18 0 0 325 915 1 1
BLM HIST1H2AJ 0 0 0 182 1 1
BLM H2AFB2 0 0 0 165 1 1
BLM OR4F21 0 0 186 186 1 1
BLM ENSG00000142539 0 0 0 378 1 1
BLM INTS3 270 0 128 340 1 1
BLM DCLRE1A 0 0 167 388 1 1
BLM DDX53 0 0 0 171 1 1
BLM PARP3 0 0 91 205 1 1
BLM PBLD 0 0 0 173 1 1
BLM CDC7 0 0 124 573 1 1
BLM PIK3C2G 0 0 0 284 1 1
BLM MND1 0 0 123 494 1 1
BLM SMC5 0 0 421 861 1 1
BLM RPA4 0 600 0 740 1 1
BLM RPUSD1 0 0 0 158 1 1
BLM FAM35A 270 0 0 270 1 1
BLM PAK2 0 0 0 228 1 1
BLM HIST1H2AI 44 0 0 329 1 1
BLM PDRG1 0 0 45 198 1 1
BLM PMS1 0 0 97 395 1 1
BLM GRB7 0 0 0 213 1 1
BLM AURKB 0 0 66 536 1 1
BLM HORMAD2 0 0 0 161 1 1
BLM SUMO3 213 900 156 970 1 1
BLM SKP2 0 0 0 171 1 2
BLM HAUS1 0 0 0 166 1 1
BLM SMARCB1 0 0 0 217 1 1
BLM H2AFZ 0 0 0 422 1 1
BLM PAK3 0 0 0 222 1 1
BLM DNASE2 0 0 0 162 1 1
BLM UBR7 0 0 155 190 1 1
BLM MTHFD1L 0 0 0 174 1 1
BLM RPS27 270 0 0 270 1 1
BLM IFIH1 0 0 0 468 1 1
BLM HIST2H3PS2 0 0 157 279 1 1
BLM ZUFSP 270 0 0 285 1 1
BLM BPTF 0 0 242 265 1 1
BLM FANCE 0 900 608 959 1 1
BLM PIF1 0 0 323 951 1 1
BLM RAD17 0 600 308 940 1 1
BLM CSE1L 0 0 0 199 1 1
BLM TRIP13 0 0 0 350 1 1
BLM RPUSD4 0 0 0 158 1 1
BLM SPC24 0 0 0 179 1 1
BLM SMARCA5 0 0 81 286 1 1
BLM NLRP5 0 0 213 213 1 1
BLM ESCO2 0 0 0 213 1 1
BLM EIF4A3 196 0 0 312 1 1
BLM CNOT7 0 0 0 170 1 1
BLM CHEK2 131 0 343 867 1 1
BLM OGG1 0 0 137 419 1 1
BLM PLK2 0 0 0 390 1 1
BLM ZMIZ1 0 0 0 331 1 1
BLM TICRR 0 0 146 456 1 1
BLM LIG3 0 0 170 443 1 1
BLM HIST2H3D 0 0 0 179 1 1
BLM UBE2U 0 0 66 303 1 1
BLM SYCE1 0 0 141 194 1 1
BLM KIAA0101 0 0 0 561 1 1
BLM EME2 0 900 206 918 1 1
BLM ZMIZ2 0 0 0 331 1 1
BLM MCM4 0 0 181 615 1 1
BLM GPR148 0 0 155 174 1 1
BLM CASP8 168 0 0 167 1 2
BLM CKAP2L 0 0 54 249 1 1
BLM H2AFX 486 900 397 977 1 1
BLM KIF20A 270 0 0 531 1 1
BLM SPAST 0 0 0 156 1 1
BLM POLG 0 0 0 183 1 1
BLM CCNB3 0 0 0 178 1 1
BLM HIST1H2AB 0 0 0 165 1 1
BLM FANCM 992 900 521 999 1 1
BLM PRIMPOL 0 0 142 367 1 1
BLM BOLA2B 0 0 0 293 1 1
BLM EIF2B4 0 0 0 225 1 1
BLM CEP152 0 0 0 230 1 1
BLM DDX55 0 0 0 201 1 1
BLM MORF4L2 44 0 156 241 1 1
BLM NDC1 0 0 0 241 1 1
BLM KDM8 0 0 720 720 1 1
BLM UBE2D4 0 0 0 197 1 1
BLM OCM2 0 0 157 156 1 1
BLM CDK6 0 0 0 260 1 2
BLM TTLL1 0 0 0 190 1 1
BLM DDX58 0 0 0 468 1 1
BLM UBE2N 0 0 73 493 1 1
BLM HIST1H2BL 0 900 0 907 1 1
BLM PARP1 270 0 282 791 1 2
BLM SPO11 0 0 323 783 1 1
BLM CPEB4 0 0 90 156 1 1
BLM SIRT7 270 0 55 429 1 2
BLM FEN1 486 0 468 982 1 1
BLM SUV39H1 0 0 0 299 1 1
BLM WRN 297 600 710 866 1 1
BLM FBXW7 486 0 0 498 1 2
BLM MCM5 0 0 150 515 1 1
BLM CSNK1E 0 0 0 670 1 1
BLM HAUS6 0 0 0 178 1 1
BLM SIRT3 0 0 43 203 1 2
BLM ANLN 0 0 0 336 1 1
BLM DNMT1 0 0 67 262 1 2
BLM GTSE1 0 0 0 308 1 1
BLM WDR70 0 0 183 217 1 1
BLM CIT 0 0 0 161 1 1
BLM EXOSC9 0 0 0 181 1 1
BLM RFC2 0 600 434 830 1 1
BLM VRK2 0 0 0 158 1 1
BLM PLK5 0 0 0 278 1 1
BLM CDC20 0 0 134 308 1 1
BLM CHEK1 419 600 391 993 1 2
BLM MTBP 0 0 0 159 1 1
BLM DNAJC9 0 0 0 237 1 1
BLM PMM2 0 0 134 469 1 1
BLM PHF21A 0 0 0 271 1 1
BLM AURKC 0 0 0 285 1 1
BLM RHOT1 0 0 0 202 1 1
BLM BORA 0 0 0 316 1 1
BLM WDR5 0 0 0 181 1 1
BLM RBMX 0 0 146 202 1 1
BLM POLD4 0 900 0 900 1 1
BLM KIF11 0 0 0 625 1 1
BLM HNRNPA1 0 0 118 190 1 1
BLM CENPJ 0 0 73 199 1 1
BLM DNA2 270 600 742 989 1 1
BLM PRDX1 0 0 0 265 1 1
BLM ATAD2 0 0 75 375 1 1
BLM XPC 0 0 96 366 1 1
BLM VCP 44 0 0 193 1 2
BLM TDRD3 0 0 0 594 1 1
BLM NEIL1 0 0 137 155 1 1
BLM UHRF2 0 0 0 155 1 1
BLM IGF2BP3 0 0 0 172 1 1
BLM HIST2H3C 0 0 0 179 1 1
BLM CLPX 0 0 54 216 1 1
BLM SHCBP1 0 0 0 372 1 1
BLM FANCA 992 900 622 999 1 1
BLM PSMB8 0 0 0 237 1 1
BLM POLQ 0 0 184 851 1 1
BLM SENP7 0 0 60 277 1 1
BLM XRN1 0 0 0 172 1 1
BLM NUPR1L 0 0 181 181 1 1
BLM SAE1 0 0 106 268 1 1
BLM RPA2 748 600 298 972 1 1
BLM RANBP2 0 0 123 188 1 1
BLM POLK 0 900 46 914 1 1
BLM UBE2B 0 0 0 466 1 1
BLM PRDX6 0 0 0 176 1 1
BLM PLK1 270 0 197 672 1 2
BLM PTGER1 0 0 0 483 1 1
BLM CCNB1 0 0 63 588 1 1
BLM MGMT 0 0 91 172 1 2
BLM HES1 0 900 0 900 1 2
BLM WHSC1 0 0 74 212 1 1
BLM FOXM1 0 0 45 293 1 1
BLM TOP3B 0 800 144 958 1 1
BLM NSF 0 0 73 509 1 2
BLM DCLRE1B 0 0 330 442 1 1
BLM MUM1 0 0 57 161 1 1
BLM POLE 0 900 123 969 1 1
BLM NFATC2IP 0 0 95 362 1 1
BLM GRB10 0 0 0 213 1 1
BLM EP400 0 0 0 320 1 1
BLM TDRD9 0 0 0 377 1 1
BLM RAD50 674 600 297 979 1 1
BLM CCDC79 0 0 201 229 1 1
BLM UBE2V2 0 0 66 740 1 1
BLM SNW1 114 0 0 198 1 1
BLM ATRX 270 0 456 679 1 1
BLM HIST1H2AC 0 0 0 296 1 1
BLM NF1 0 0 91 161 1 1
BLM APTX 0 0 87 501 1 1
BLM KSR2 270 0 0 271 1 1
BLM CHD7 0 0 0 267 1 1
BLM LARS2 0 0 90 472 1 1
BLM DNMT3B 0 0 297 379 1 1
BLM HMGB2 0 0 0 200 1 1
BLM DNMT3A 0 0 297 297 1 2
BLM XPA 0 0 253 586 1 1
BLM UHRF1 0 0 297 467 1 1
BLM SLX1A 0 0 299 898 1 1
BLM RECQL 0 0 681 237 1 1
BLM SPDL1 0 0 0 230 1 1
BLM WRNIP1 0 0 113 763 1 1
BLM ETAA1 270 0 123 344 1 1
BLM SMARCAL1 0 0 294 491 1 1
BLM DDX18 0 0 0 193 1 1
BLM H2AFV 0 0 0 412 1 1
BLM CDK2 0 650 134 811 1 2
BLM CDC73 0 0 74 215 1 1
BLM MCMDC2 0 0 48 231 1 1
BLM CDCA5 0 0 0 345 1 1
BLM CNTD2 0 0 0 175 1 1
BLM SIRT5 0 0 0 245 1 1
BLM BOD1L2 0 0 0 272 1 1
BLM RINT1 0 0 118 151 1 1
BLM RAD54L 0 0 285 935 1 1
BLM WDR76 0 0 154 326 1 1
BLM CBX3 0 0 307 352 1 1
BLM H3F3A 0 0 95 226 1 1
BLM UBE2A 0 0 0 469 1 1
BLM SLC25A1 0 0 0 190 1 1
BLM LEPRE1 0 0 242 241 1 1
BLM E2F6 0 0 54 184 1 1
BLM ATRIP 0 600 391 747 1 1
BLM CENPM 0 0 0 330 1 1
BLM CCNF 0 0 0 202 1 1
BLM SUMO4 0 0 57 617 1 1
BLM CXorf57 0 0 163 163 1 1
BLM PALB2 0 600 284 715 1 1
BLM SMARCAD1 0 0 117 679 1 1
BLM CHD6 0 0 0 267 1 1
BLM CORO7 259 0 0 258 1 1
BLM BOD1 0 0 150 355 1 1
BLM KAT7 0 0 0 231 1 1
BLM DDX21 0 0 0 198 1 1
BLM HELQ 0 0 174 567 1 1
BLM APEX2 0 0 0 201 1 1
BLM FIGNL1 0 0 49 227 1 1
BLM MSH5 0 600 211 876 1 1
BLM CT55 0 0 0 225 1 1
BLM NOTCH1 0 0 296 311 1 2
BLM RMI1 883 900 838 999 1 1
BLM ARPC2 0 0 0 215 1 1
BLM LMNA 0 0 325 339 1 2
BLM EXO1 675 600 650 999 1 1
BLM KIF15 0 0 0 680 1 1
BLM TTLL10 0 0 0 160 1 1
BLM GNL3 0 0 0 169 1 1
BLM UCHL5 0 0 0 190 1 1
BLM EME1 0 900 391 981 1 1
BLM RNASEH2A 0 0 234 840 1 1
BLM CCS 0 0 0 290 1 2
BLM CDK4 0 800 56 845 1 2
BLM ERCC2 0 0 125 493 1 1
BLM GART 0 0 0 346 1 1
BLM TTLL9 0 0 0 190 1 1
BLM RNF40 0 0 0 249 1 1
BLM TTBK2 0 0 0 158 1 1
BLM DDX54 0 0 50 182 1 1
BLM CKS1B 0 0 134 268 1 1
BLM AGO2 0 0 75 262 1 2
BLM CDK14 0 0 0 386 1 1
BLM EXOSC10 0 0 60 266 1 1
BLM RBBP6 0 0 0 175 1 1
BLM UBE2T 0 900 72 932 1 1
BLM EZH2 0 0 291 454 1 2
BLM CLCNKB 0 0 0 205 1 1
BLM HELB 0 0 81 501 1 1
BLM XRCC6 0 0 446 953 1 1
BLM DYNLL1 270 0 0 288 1 1
BLM NASP 0 0 103 265 1 1
BLM SRSF1 0 0 193 429 1 1
BLM KIF4A 0 0 0 402 1 1
BLM HDDC3 0 0 0 153 1 1
BLM NPRL2 0 0 0 163 1 1
BLM PAK1 0 0 0 222 1 2
BLM TPR 0 0 0 359 1 1
BLM ANP32E 0 0 71 155 1 1
BLM FNTA 128 0 0 158 1 1
BLM KIF18B 0 0 0 196 1 1
BLM SKIV2L 0 0 52 217 1 1
BLM PSME3 0 0 0 150 1 1
BLM PIK3CA 0 0 0 284 1 2
BLM RIOK1 0 0 0 459 1 1
BLM NDNL2 0 0 81 170 1 1
BLM TOP3A 900 900 882 999 1 1
BLM H2AFB3 0 0 0 165 1 1
BLM MX1 192 0 0 228 1 1
BLM RNF168 0 0 181 222 1 1
BLM HNRNPUL1 0 0 181 226 1 1
BLM MLH3 0 650 75 882 1 1
BLM KIF2C 0 0 0 570 1 1
BLM GRB14 0 0 0 213 1 1
BLM UBE2D1 0 0 0 197 1 1
BLM HIST1H2BD 0 900 0 904 1 1
BLM POLL 0 0 139 192 1 1
BLM MYC 421 0 217 527 1 2
BLM CENPU 0 0 95 581 1 1
BLM APEX1 0 0 150 357 1 1
BLM WDR12 0 0 0 156 1 1
BLM DDX47 0 0 0 155 1 1
BLM DDX27 0 0 0 178 1 1
BLM KIF18A 0 0 0 344 1 1
BLM HIST1H2BM 0 900 0 901 1 1
BLM ODC1 0 0 54 189 1 1
BLM RNF212 0 0 155 393 1 1
BLM DHX58 0 0 0 468 1 1
BLM GINS1 0 0 0 231 1 1
BLM MECP2 234 0 81 265 1 1
BLM EIF2B5 0 0 57 179 1 1
BLM PAK7 0 0 0 177 1 1
BLM UNC13D 0 0 0 189 1 1
BLM UBE2K 0 0 108 217 1 1
BLM AHCYL1 0 0 0 188 1 1
BLM AGO4 0 0 43 236 1 1
BLM SPAG5 0 0 0 549 1 1
BLM KIFC1 0 0 0 163 1 1
BLM SYCE2 0 0 161 181 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0043138 Molecular Function 3'-5' DNA helicase activity enables IBA
GO:0043138 Molecular Function 3'-5' DNA helicase activity enables TAS
GO:1905773 Molecular Function 8-hydroxy-2'-deoxyguanosine DNA binding enables IDA
GO:0005524 Molecular Function ATP binding enables IDA
GO:0016887 Molecular Function ATP hydrolysis activity enables IEA
GO:0008094 Molecular Function ATP-dependent activity, acting on DNA enables IDA
GO:0003677 Molecular Function DNA binding enables IDA
GO:0003678 Molecular Function DNA helicase activity enables IDA
GO:0003678 Molecular Function DNA helicase activity enables IMP
GO:1990814 Molecular Function DNA/DNA annealing activity enables IDA
GO:0051880 Molecular Function G-quadruplex DNA binding enables IDA
GO:0000403 Molecular Function Y-form DNA binding enables IDA
GO:0000405 Molecular Function bubble DNA binding enables IDA
GO:0061749 Molecular Function forked DNA-dependent helicase activity enables IDA
GO:0000400 Molecular Function four-way junction DNA binding enables IDA
GO:0009378 Molecular Function four-way junction helicase activity enables IBA
GO:0009378 Molecular Function four-way junction helicase activity enables IDA
GO:0004386 Molecular Function helicase activity enables IDA
GO:0042802 Molecular Function identical protein binding enables IDA
GO:0140677 Molecular Function molecular function activator activity enables IDA
GO:0002039 Molecular Function p53 binding enables IPI
GO:0005515 Molecular Function protein binding enables IPI
GO:0042803 Molecular Function protein homodimerization activity enables IDA
GO:0003697 Molecular Function single-stranded DNA binding enables IDA
GO:0061821 Molecular Function telomeric D-loop binding enables IDA
GO:0061849 Molecular Function telomeric G-quadruplex DNA binding enables IDA
GO:0008270 Molecular Function zinc ion binding enables IDA
GO:0006974 Biological Process DNA damage response involved_in IDA
GO:0006974 Biological Process DNA damage response involved_in IMP
GO:0000729 Biological Process DNA double-strand break processing involved_in IDA
GO:0032508 Biological Process DNA duplex unwinding involved_in IDA
GO:0006310 Biological Process DNA recombination involved_in NAS
GO:0006281 Biological Process DNA repair involved_in NAS
GO:0006260 Biological Process DNA replication involved_in ISS
GO:0006268 Biological Process DNA unwinding involved in DNA replication involved_in IBA
GO:0044806 Biological Process G-quadruplex DNA unwinding involved_in IBA
GO:0044806 Biological Process G-quadruplex DNA unwinding involved_in IDA
GO:0044806 Biological Process G-quadruplex DNA unwinding involved_in ISS
GO:0072757 Biological Process cellular response to camptothecin involved_in IDA
GO:0072711 Biological Process cellular response to hydroxyurea involved_in IDA
GO:0071479 Biological Process cellular response to ionizing radiation involved_in IDA
GO:0000724 Biological Process double-strand break repair via homologous recombination involved_in IBA
GO:0000724 Biological Process double-strand break repair via homologous recombination involved_in IDA
GO:0000724 Biological Process double-strand break repair via homologous recombination involved_in NAS
GO:0007095 Biological Process mitotic G2 DNA damage checkpoint signaling involved_in IDA
GO:0045910 Biological Process negative regulation of DNA recombination involved_in IMP
GO:0051782 Biological Process negative regulation of cell division involved_in IMP
GO:0045893 Biological Process positive regulation of DNA-templated transcription involved_in IDA
GO:0051259 Biological Process protein complex oligomerization involved_in IDA
GO:0051260 Biological Process protein homooligomerization involved_in IDA
GO:0090329 Biological Process regulation of DNA-templated DNA replication involved_in IMP
GO:0000079 Biological Process regulation of cyclin-dependent protein serine/threonine kinase activity involved_in IMP
GO:0031297 Biological Process replication fork processing involved_in IDA
GO:0071139 Biological Process resolution of DNA recombination intermediates involved_in IDA
GO:0010165 Biological Process response to X-ray involved_in IDA
GO:0090656 Biological Process t-circle formation involved_in TAS
GO:0000723 Biological Process telomere maintenance involved_in IBA
GO:0032201 Biological Process telomere maintenance via semi-conservative replication involved_in TAS
GO:0061820 Biological Process telomeric D-loop disassembly involved_in IDA
GO:0016605 Cellular Component PML body colocalizes_with IDA
GO:0016605 Cellular Component PML body located_in IDA
GO:0031422 Cellular Component RecQ family helicase-topoisomerase III complex part_of IPI
GO:0005694 Cellular Component chromosome is_active_in IBA
GO:0000781 Cellular Component chromosome, telomeric region colocalizes_with IDA
GO:0005737 Cellular Component cytoplasm is_active_in IBA
GO:0005829 Cellular Component cytosol located_in IDA
GO:0000800 Cellular Component lateral element located_in IDA
GO:0000228 Cellular Component nuclear chromosome located_in IDA
GO:0016363 Cellular Component nuclear matrix located_in IDA
GO:0005730 Cellular Component nucleolus located_in IDA
GO:0005654 Cellular Component nucleoplasm located_in IDA
GO:0005654 Cellular Component nucleoplasm located_in TAS
GO:0005634 Cellular Component nucleus is_active_in IBA
GO:0005634 Cellular Component nucleus located_in IDA
GO:0005634 Cellular Component nucleus located_in NAS
GO:0032991 Cellular Component protein-containing complex part_of IDA
GO:0005657 Cellular Component replication fork located_in ISS
Pathways
Name DB ID
Reproduction Reactome R-HSA-1474165
Meiosis Reactome R-HSA-1500620
Telomere Maintenance Reactome R-HSA-157579
Cell Cycle Reactome R-HSA-1640170
Disease Reactome R-HSA-1643685
Processive synthesis on the C-strand of the telomere Reactome R-HSA-174414
Telomere C-strand (Lagging Strand) Synthesis Reactome R-HSA-174417
Extension of Telomeres Reactome R-HSA-180786
Generic Transcription Pathway Reactome R-HSA-212436
SUMOylation Reactome R-HSA-2990846
SUMOylation of DNA damage response and repair proteins Reactome R-HSA-3108214
SUMO E3 ligases SUMOylate target proteins Reactome R-HSA-3108232
Transcriptional Regulation by TP53 Reactome R-HSA-3700989
Metabolism of proteins Reactome R-HSA-392499
Regulation of TP53 Activity Reactome R-HSA-5633007
HDR through Single Strand Annealing (SSA) Reactome R-HSA-5685938
HDR through Homologous Recombination (HRR) Reactome R-HSA-5685942
DNA Double-Strand Break Repair Reactome R-HSA-5693532
Resolution of D-Loop Structures Reactome R-HSA-5693537
Homology Directed Repair Reactome R-HSA-5693538
Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) Reactome R-HSA-5693554
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) Reactome R-HSA-5693567
Resolution of D-loop Structures through Holliday Junction Intermediates Reactome R-HSA-5693568
Homologous DNA Pairing and Strand Exchange Reactome R-HSA-5693579
Processing of DNA double-strand break ends Reactome R-HSA-5693607
Presynaptic phase of homologous DNA pairing and strand exchange Reactome R-HSA-5693616
Post-translational protein modification Reactome R-HSA-597592
Regulation of TP53 Activity through Phosphorylation Reactome R-HSA-6804756
G2/M DNA damage checkpoint Reactome R-HSA-69473
G2/M Checkpoints Reactome R-HSA-69481
Cell Cycle Checkpoints Reactome R-HSA-69620
RNA Polymerase II Transcription Reactome R-HSA-73857
Chromosome Maintenance Reactome R-HSA-73886
DNA Repair Reactome R-HSA-73894
Gene expression (Transcription) Reactome R-HSA-74160
Meiotic recombination Reactome R-HSA-912446
Diseases of DNA repair Reactome R-HSA-9675135
Diseases of DNA Double-Strand Break Repair Reactome R-HSA-9675136
Defective homologous recombination repair (HRR) due to BRCA2 loss of function Reactome R-HSA-9701190
Defective homologous recombination repair (HRR) due to BRCA1 loss of function Reactome R-HSA-9701192
Defective homologous recombination repair (HRR) due to PALB2 loss of function Reactome R-HSA-9701193
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function Reactome R-HSA-9704331
Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function Reactome R-HSA-9704646
Impaired BRCA2 binding to RAD51 Reactome R-HSA-9709570
Impaired BRCA2 binding to PALB2 Reactome R-HSA-9709603
DNA IR-double strand breaks and cellular response via ATM (WP3959) WikiPathways WP3959_r118468
Integrated cancer pathway (WP1971) WikiPathways WP1971_r117762
Transcripts
Accession Version MolecularType Name NCBI Comments
NM_001287246 2 mRNA transcript variant 2 NC_000015 Reference
NM_001287248 2 mRNA transcript variant 4 NC_000015 Reference
NM_000057 4 mRNA transcript variant 1 NC_000015 Reference
NM_001287247 2 mRNA transcript variant 3 NC_000015 Reference
XM_011521882 4 mRNA transcript variant X2 NC_000015 Reference
XM_047432934 1 mRNA transcript variant X1 NC_000015 Reference
XM_006720632 3 mRNA transcript variant X3 NC_000015 Reference