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DEPTOR

DEP domain containing MTOR interacting protein
General Information
Name DEP domain containing MTOR interacting protein
Alias
  • DEP domain-containing mTOR-interacting protein
  • DEP domain containing 6
  • DEP domain-containing protein 6
Gene_family PDZ domain containing
organism Homo sapiens
entrez_id 64798
location 8q24.12
transcript_count 2
exon_count 9
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez Involved in several processes, including negative regulation of TOR signaling; negative regulation of cell size; and negative regulation of protein kinase activity. [provided by Alliance of Genome Resources, Apr 2022]
    Stringdb DEP domain-containing mTOR-interacting protein; Negative regulator of the mTORC1 and mTORC2 signaling pathways. Inhibits the kinase activity of both complexes; PDZ domain containing
    nextProt Negative regulator of the mTORC1 and mTORC2 signaling pathways. Inhibits the kinase activity of both complexes.
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
DEPTOR BioGRID OBI1 GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID ERGIC1 GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID ZC3HAV1 GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID RNF126 GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID ERAP1 GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID ERGIC3 GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID UBR5 GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID DCAF8 GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID EIF3K GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID AGO2 GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID MYCBP2 GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID COPG1 GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID SYNRG GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID AKAP11 GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID LSM6 GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID PIM2 GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID IMMT GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID MAGED2 GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID DDX39A GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID KEAP1 GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID EIF2B3 GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID SQSTM1 GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID MAPKAPK5 GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID UBL4A GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID CCDC6 GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID BAG6 GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID USP7 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
DEPTOR BioGRID UQCRC1 GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID UBE3A GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID TFRC GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID SMARCB1 GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID SCD GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID ATXN2 GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID PSME1 GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID PSMD13 GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID PSMB3 GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID MAPK3 GeneID BioGRID Biochemical Activity
DEPTOR BioGRID PRKAR2A GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID PRKACA GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID PPP2CB GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID OPA1 GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID NDUFB4 GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID MYO1C GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID LGALS7 GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID LAMB3 GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID KIF2A GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID MTOR GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity
DEPTOR BioGRID CSK GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID CNP GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID AUP1 GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID ARHGAP4 GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID ARF4 GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID PTBP2 GeneID BioGRID Co-fractionation
DEPTOR BioGRID NUMB GeneID BioGRID Affinity Capture-Western
DEPTOR BioGRID BTRC GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity; Reconstituted Complex; Two-hybrid
DEPTOR BioGRID ERBB2 GeneID BioGRID Affinity Capture-Western; Co-localization
DEPTOR BioGRID ANKRD11 GeneID BioGRID Two-hybrid
DEPTOR BioGRID NRAS GeneID BioGRID Proximity Label-MS
DEPTOR BioGRID TNFAIP3 GeneID BioGRID Affinity Capture-Western; Co-localization; Reconstituted Complex; Two-hybrid
DEPTOR BioGRID OTUB1 GeneID BioGRID Affinity Capture-Western
DEPTOR BioGRID HNRNPL GeneID BioGRID Affinity Capture-RNA
DEPTOR BioGRID TRIM16 GeneID BioGRID Affinity Capture-Western
DEPTOR BioGRID FBXW7 GeneID BioGRID Affinity Capture-Western
DEPTOR BioGRID FBXW11 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
DEPTOR BioGRID RPS6KB1 GeneID BioGRID Biochemical Activity
DEPTOR BioGRID RPS6KA1 GeneID BioGRID Biochemical Activity
DEPTOR BioGRID TRIM41 GeneID BioGRID Two-hybrid
DEPTOR BioGRID PSME3 GeneID BioGRID Two-hybrid
DEPTOR BioGRID XPO1 GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID CUL5 GeneID BioGRID Biochemical Activity
DEPTOR BioGRID NXF1 GeneID BioGRID Affinity Capture-RNA
DEPTOR BioGRID CCDC110 GeneID BioGRID Two-hybrid
DEPTOR BioGRID TRAF1 GeneID BioGRID Two-hybrid
DEPTOR BioGRID FBXO25 GeneID BioGRID Biochemical Activity
DEPTOR BioGRID RICTOR GeneID BioGRID Affinity Capture-Western
DEPTOR BioGRID RPTOR GeneID BioGRID Affinity Capture-Western
DEPTOR BioGRID APP GeneID BioGRID Reconstituted Complex
DEPTOR BioGRID MLST8 GeneID BioGRID Affinity Capture-MS
DEPTOR BioGRID CUL1 GeneID BioGRID Affinity Capture-Western
DEPTOR BioGRID CHKA GeneID BioGRID Biochemical Activity
DEPTOR BioGRID LNX1 GeneID BioGRID Reconstituted Complex
StringDB
A B experiments database textmining combined score hadb nhadb
DEPTOR PDE1C 0 0 96 152 1 1
DEPTOR PLD1 0 0 277 415 1 2
DEPTOR ULK1 0 600 519 799 1 2
DEPTOR API5 0 0 0 258 1 1
DEPTOR PRKCA 0 0 520 520 1 1
DEPTOR RPS6KA1 270 0 492 616 1 1
DEPTOR SKP2 0 0 249 248 1 2
DEPTOR PRKAB1 0 0 181 181 1 2
DEPTOR AKT3 0 0 268 273 1 2
DEPTOR MAPK8 0 0 202 202 1 2
DEPTOR FNIP1 0 0 296 296 1 1
DEPTOR DAPK3 0 0 118 250 1 2
DEPTOR CHKA 270 0 0 270 1 1
DEPTOR FKBP1A 0 0 708 727 1 2
DEPTOR RPS6KB2 0 600 382 745 1 2
DEPTOR TDP2 0 0 260 306 1 1
DEPTOR ATG10 0 0 253 252 1 2
DEPTOR ARHGEF3 0 0 280 295 1 1
DEPTOR PXN 0 0 195 195 1 1
DEPTOR SESN2 0 0 392 442 1 2
DEPTOR KPTN 0 0 180 179 1 1
DEPTOR OTUB1 270 0 155 368 1 1
DEPTOR TNS1 0 0 184 183 1 1
DEPTOR MAP1LC3B 0 0 233 251 1 2
DEPTOR HMGCL 0 0 53 158 1 1
DEPTOR PPARA 0 0 181 198 1 2
DEPTOR YIPF1 0 0 141 213 1 1
DEPTOR ATG5 0 0 325 325 1 2
DEPTOR PDCD4 0 0 294 294 1 2
DEPTOR RPTOR 486 900 989 999 1 2
DEPTOR PIK3R1 0 0 181 181 1 1
DEPTOR HSPA4 0 0 150 173 1 1
DEPTOR MCL1 0 0 232 231 1 2
DEPTOR INPP4A 0 0 73 216 1 1
DEPTOR DDIT4L 0 0 265 278 1 1
DEPTOR NUAK1 0 0 168 167 1 1
DEPTOR SIRT1 0 0 263 263 1 2
DEPTOR EGF 0 0 185 185 1 2
DEPTOR DEPDC1 0 0 61 159 1 1
DEPTOR RPS6KA3 0 0 275 275 1 1
DEPTOR SESN3 0 0 249 265 1 1
DEPTOR TRAF6 0 0 162 161 1 2
DEPTOR SMARCD2 0 0 130 190 1 1
DEPTOR DKK4 0 0 53 215 1 1
DEPTOR FLCN 0 0 336 340 1 1
DEPTOR MRPL35 0 0 0 188 1 1
DEPTOR NFKBIA 0 0 181 181 1 2
DEPTOR UBE2M 0 0 205 205 1 1
DEPTOR LEP 0 0 181 181 1 1
DEPTOR AMBRA1 0 0 392 392 1 2
DEPTOR SMAD3 0 0 174 173 1 2
DEPTOR RNF157 0 0 112 167 1 1
DEPTOR SREBF1 0 0 334 334 1 1
DEPTOR RPS24 0 0 0 418 1 1
DEPTOR ENSG00000248405 0 0 0 187 1 1
DEPTOR AKR7A2 0 0 75 234 1 1
DEPTOR KAT5 0 0 57 202 1 1
DEPTOR LGALS1 0 0 0 202 1 1
DEPTOR EP300 0 0 87 217 1 2
DEPTOR EIF4EBP3 0 0 137 193 1 1
DEPTOR CUL1 270 0 533 645 1 1
DEPTOR PTEN 0 0 469 478 1 2
DEPTOR ZMYM4 0 0 103 192 1 1
DEPTOR GABARAP 0 0 189 189 1 2
DEPTOR VEGFA 0 0 190 190 1 2
DEPTOR ARHGAP8 0 0 0 187 1 1
DEPTOR ALB 0 0 136 189 1 2
DEPTOR TELO2 0 0 565 662 1 1
DEPTOR RRAGB 0 900 517 953 1 1
DEPTOR WIPI1 0 0 248 248 1 2
DEPTOR TMEM14A 0 0 95 341 1 1
DEPTOR EIF4A1 0 0 321 325 1 1
DEPTOR CUL5 270 0 255 432 1 1
DEPTOR WNT1 0 0 58 158 1 2
DEPTOR PREX1 0 0 294 188 1 1
DEPTOR ATG7 0 0 325 325 1 2
DEPTOR TJP1 0 0 438 438 1 1
DEPTOR DAPK2 0 0 451 451 1 2
DEPTOR RPS3A 0 0 67 209 1 1
DEPTOR MAF 0 0 579 579 1 1
DEPTOR SNAI1 0 0 158 157 1 1
DEPTOR SLC3A2 0 0 183 189 1 1
DEPTOR GLMN 0 0 207 207 1 1
DEPTOR DAP 0 0 280 306 1 2
DEPTOR ATM 0 0 417 417 1 2
DEPTOR TRIM63 0 0 209 209 1 1
DEPTOR EIF3F 0 0 180 179 1 1
DEPTOR IGF2 0 0 117 216 1 1
DEPTOR MIOS 0 0 261 261 1 1
DEPTOR TTI1 0 0 977 978 1 1
DEPTOR SIRT6 0 0 169 169 1 2
DEPTOR EXOC3L4 0 0 124 362 1 1
DEPTOR ANKRD11 268 0 0 268 1 1
DEPTOR C11orf87 0 0 128 179 1 1
DEPTOR YWHAG 0 900 0 915 1 1
DEPTOR CWC25 0 0 82 212 1 1
DEPTOR SLC38A2 0 0 189 189 1 1
DEPTOR GATSL3 0 0 367 380 1 1
DEPTOR GSK3B 0 0 182 264 1 2
DEPTOR ATG9A 0 0 112 167 1 2
DEPTOR CRTC2 0 0 150 173 1 1
DEPTOR SFN 0 900 0 901 1 2
DEPTOR INSR 0 0 157 156 1 1
DEPTOR RHOA 0 0 184 183 1 2
DEPTOR EIF4G1 0 0 455 455 1 2
DEPTOR SIRT7 0 0 181 181 1 2
DEPTOR GABARAPL1 0 0 271 271 1 2
DEPTOR YWHAH 0 900 0 901 1 1
DEPTOR DEPDC1B 0 0 87 227 1 1
DEPTOR PDK2 0 0 242 264 1 1
DEPTOR LAMTOR1 0 0 426 461 1 1
DEPTOR INPP4B 0 0 134 267 1 1
DEPTOR PIK3CD 0 0 210 210 1 1
DEPTOR RPL8 0 0 0 329 1 1
DEPTOR FBXO5 0 0 212 212 1 1
DEPTOR USP6 0 0 195 195 1 1
DEPTOR ATG16L1 0 0 248 248 1 2
DEPTOR TBC1D7 0 0 557 568 1 2
DEPTOR PLA2G2D 0 0 49 180 1 1
DEPTOR DEPDC7 0 0 106 243 1 1
DEPTOR TOR1B 0 0 0 218 1 1
DEPTOR CASP3 0 0 265 265 1 2
DEPTOR SNTB1 0 0 142 162 1 1
DEPTOR CEBPA 0 0 107 151 1 1
DEPTOR KAT8 0 0 60 156 1 1
DEPTOR COL14A1 0 0 227 251 1 1
DEPTOR EIF4B 0 0 460 480 1 1
DEPTOR TFEB 0 0 394 394 1 2
DEPTOR LNX1 270 0 90 321 1 1
DEPTOR ATG101 0 0 374 374 1 2
DEPTOR HSP90AA1 0 0 150 173 1 2
DEPTOR RNF152 0 0 204 204 1 1
DEPTOR CPSF4 0 0 54 204 1 1
DEPTOR PLD2 0 0 234 291 1 1
DEPTOR FBXW7 270 0 182 441 1 2
DEPTOR HNRNPL 270 0 0 270 1 1
DEPTOR CTSZ 0 0 68 270 1 1
DEPTOR MAPK3 0 0 293 301 1 2
DEPTOR SIRT3 0 0 155 154 1 2
DEPTOR CUL4A 0 0 148 167 1 1
DEPTOR PRR5L 0 0 663 672 1 1
DEPTOR DDIAS 0 0 113 306 1 1
DEPTOR SQSTM1 0 0 279 279 1 2
DEPTOR BNIP3 0 0 244 243 1 2
DEPTOR ACTB 0 0 242 241 1 2
DEPTOR CCDC110 294 0 0 294 1 1
DEPTOR ATG13 0 0 529 569 1 2
DEPTOR INS 0 0 460 459 1 2
DEPTOR ATG12 0 0 293 293 1 2
DEPTOR FOXG1 0 0 0 179 1 1
DEPTOR ETV7 0 0 134 153 1 1
DEPTOR PIK3CG 0 0 166 165 1 1
DEPTOR JAK3 0 0 0 197 1 1
DEPTOR ULK2 0 600 324 718 1 2
DEPTOR PIK3CB 0 0 244 243 1 1
DEPTOR PMAIP1 0 0 234 234 1 2
DEPTOR AUH 0 0 124 217 1 1
DEPTOR SIX4 0 0 171 185 1 1
DEPTOR EVI2B 0 0 134 155 1 1
DEPTOR WEE1 0 0 181 198 1 1
DEPTOR EEF2K 0 0 391 420 1 2
DEPTOR EIF4EBP2 0 0 338 343 1 1
DEPTOR AKT1S1 0 900 989 998 1 1
DEPTOR BECN1 0 0 370 370 1 2
DEPTOR SMARCD3 0 0 288 288 1 1
DEPTOR MAFB 0 0 642 642 1 1
DEPTOR DAPK1 0 0 181 211 1 2
DEPTOR LPIN1 0 0 400 413 1 2
DEPTOR JUN 0 0 212 212 1 2
DEPTOR CDT1 0 0 166 165 1 1
DEPTOR DSCAM 0 0 0 558 1 1
DEPTOR MAPK12 0 0 113 171 1 1
DEPTOR CDC25A 0 0 145 172 1 1
DEPTOR POLDIP3 0 0 277 277 1 1
DEPTOR MTHFD2 0 0 150 168 1 1
DEPTOR TSC1 0 900 603 958 1 2
DEPTOR RRAGD 0 900 468 944 1 1
DEPTOR BCL2L11 0 0 240 239 1 2
DEPTOR CSNK1A1 0 0 253 252 1 1
DEPTOR RRAGC 0 900 665 965 1 1
DEPTOR MSTN 0 0 134 168 1 1
DEPTOR RPS11 0 0 0 301 1 1
DEPTOR NPRL3 0 0 284 284 1 1
DEPTOR NCK2 0 0 43 262 1 1
DEPTOR UBE2F 0 0 180 179 1 1
DEPTOR LAMP2 0 0 235 236 1 2
DEPTOR WDR59 0 0 246 245 1 1
DEPTOR YWHAE 0 900 0 901 1 1
DEPTOR KDM4A 0 0 474 474 1 1
DEPTOR GNMT 0 0 524 564 1 1
DEPTOR YWHAZ 0 900 90 906 1 1
DEPTOR KRAS 0 0 143 277 1 2
DEPTOR FOXO1 0 0 393 401 1 2
DEPTOR FAM84B 0 0 167 197 1 1
DEPTOR DEPDC5 0 0 342 342 1 1
DEPTOR IRS2 0 0 259 258 1 1
DEPTOR MLST8 486 900 989 999 1 1
DEPTOR EIF4A2 0 0 323 323 1 1
DEPTOR BTRC 879 0 847 980 1 1
DEPTOR NRAS 169 0 82 226 1 1
DEPTOR TFE3 0 0 167 302 1 2
DEPTOR NRBP2 0 0 134 151 1 1
DEPTOR SIRT2 0 0 158 157 1 2
DEPTOR C12orf66 0 0 203 203 1 1
DEPTOR RGS4 0 0 60 204 1 1
DEPTOR ZKSCAN3 0 0 163 163 1 2
DEPTOR FBXO32 0 0 240 239 1 2
DEPTOR ERBB2 0 0 166 182 1 2
DEPTOR LAMTOR5 0 0 282 282 1 1
DEPTOR SLC38A9 0 0 452 461 1 1
DEPTOR ANXA5 0 0 150 187 1 2
DEPTOR FBXO25 270 0 0 270 1 1
DEPTOR USP9X 0 0 54 153 1 1
DEPTOR CDC16 0 0 170 169 1 1
DEPTOR SPATA13 0 0 0 208 1 1
DEPTOR ATOH1 0 0 0 189 1 1
DEPTOR SIRT4 0 0 187 187 1 1
DEPTOR ARF1 0 0 181 198 1 1
DEPTOR SEH1L 0 0 206 206 1 1
DEPTOR FOXO4 0 0 202 229 1 1
DEPTOR EIF4EBP1 0 0 720 734 1 2
DEPTOR RNF7 0 0 323 323 1 1
DEPTOR GRB10 0 0 391 406 1 1
DEPTOR NF1 0 0 215 215 1 1
DEPTOR MAP2K7 0 0 270 270 1 1
DEPTOR ATP7A 0 0 164 163 1 1
DEPTOR PRR5 0 900 977 997 1 1
DEPTOR IKBKB 0 0 167 167 1 2
DEPTOR SMG1 0 0 335 335 1 1
DEPTOR GABARAPL2 0 0 270 270 1 2
DEPTOR FKBP8 0 0 630 630 1 1
DEPTOR LARS2 0 0 324 335 1 1
DEPTOR ATG14 0 0 384 394 1 2
DEPTOR GAPDH 0 0 283 282 1 2
DEPTOR PPP2R4 0 0 216 216 1 1
DEPTOR PML 0 900 0 900 1 2
DEPTOR STEAP1B 0 0 193 193 1 1
DEPTOR BCL2L1 0 0 218 218 1 2
DEPTOR AKT1 0 900 662 965 1 2
DEPTOR STRADA 0 0 135 153 1 1
DEPTOR PPARG 0 0 259 258 1 2
DEPTOR KLF6 0 0 53 150 1 1
DEPTOR PREX2 0 0 374 228 1 1
DEPTOR PHLPP1 0 0 265 291 1 2
DEPTOR ATF4 0 0 164 216 1 2
DEPTOR PIK3R4 0 0 287 286 1 2
DEPTOR BNIP3L 0 0 181 181 1 2
DEPTOR TSC2 0 900 682 969 1 2
DEPTOR DDB1 0 0 134 184 1 1
DEPTOR MTSS1 0 0 136 209 1 1
DEPTOR RAB7B 0 0 223 223 1 1
DEPTOR RBX1 0 0 335 335 1 1
DEPTOR MCCC1 0 0 56 202 1 1
DEPTOR TRRAP 0 0 217 230 1 1
DEPTOR EFCAB3 0 0 120 153 1 1
DEPTOR LURAP1L 0 0 96 150 1 1
DEPTOR ZFYVE1 0 0 201 201 1 2
DEPTOR MAP1LC3A 0 0 142 225 1 2
DEPTOR HRAS 0 0 181 256 1 2
DEPTOR CTNNB1 0 0 230 229 1 2
DEPTOR NIPAL3 0 0 117 169 1 1
DEPTOR CDKN1B 0 0 141 173 1 2
DEPTOR SLC1A7 0 0 291 290 1 1
DEPTOR MGST1 0 0 0 216 1 1
DEPTOR SEC13 0 0 491 516 1 1
DEPTOR TCHP 0 0 189 189 1 1
DEPTOR NDRG1 0 0 218 240 1 1
DEPTOR STX17 0 0 117 163 1 2
DEPTOR RAC2 0 0 274 274 1 1
DEPTOR NAE1 0 0 218 218 1 1
DEPTOR YY1 0 0 157 156 1 1
DEPTOR SKP1 0 0 332 332 1 2
DEPTOR RPL12 0 0 0 260 1 1
DEPTOR SIRT5 0 0 171 171 1 1
DEPTOR JAK1 0 0 81 177 1 2
DEPTOR ARHGEF4 0 0 0 208 1 1
DEPTOR RRAGA 0 900 556 957 1 1
DEPTOR SH3BP4 0 0 183 183 1 1
DEPTOR NEDD4 0 0 160 159 1 2
DEPTOR HIF1A 0 0 372 372 1 2
DEPTOR RPS6 0 0 556 565 1 2
DEPTOR PLEK 0 0 458 463 1 1
DEPTOR ATG3 0 0 262 262 1 2
DEPTOR FBXW9 0 0 97 200 1 1
DEPTOR FOXO6 0 0 154 153 1 1
DEPTOR FBXW11 745 0 142 771 1 1
DEPTOR GATSL2 0 0 183 200 1 1
DEPTOR EIF2AK3 0 0 155 154 1 2
DEPTOR IL6 0 0 156 155 1 2
DEPTOR ACLY 0 0 150 188 1 1
DEPTOR PIK3C3 0 0 415 414 1 2
DEPTOR CHMP2B 0 0 74 173 1 2
DEPTOR WDR24 0 0 268 268 1 1
DEPTOR DGAT2 0 0 42 303 1 1
DEPTOR NAT10 0 0 108 199 1 1
DEPTOR YWHAB 0 900 84 906 1 1
DEPTOR MAPKAP1 0 900 817 992 1 1
DEPTOR MTOR 675 900 989 999 1 2
DEPTOR FBXW5 0 0 220 220 1 1
DEPTOR KDM4B 0 0 456 456 1 1
DEPTOR FOXO3 0 0 366 366 1 2
DEPTOR SRC 0 0 200 205 1 2
DEPTOR NOTCH1 0 0 173 173 1 2
DEPTOR RPL14 0 0 0 303 1 1
DEPTOR CDC42 0 0 153 152 1 2
DEPTOR RAB10 0 0 253 252 1 1
DEPTOR DDIT3 0 0 90 189 1 2
DEPTOR SLC7A5 0 0 246 245 1 1
DEPTOR NOL6 0 0 74 168 1 1
DEPTOR CUL2 0 0 164 186 1 1
DEPTOR CCND1 0 0 330 330 1 2
DEPTOR HK2 0 0 167 189 1 2
DEPTOR NOS3 0 0 81 204 1 2
DEPTOR PC 0 0 61 180 1 1
DEPTOR RPS6KB1 270 600 710 911 1 2
DEPTOR EGFR 0 0 247 246 1 2
DEPTOR KAT2B 0 0 52 196 1 1
DEPTOR REM1 0 0 0 202 1 1
DEPTOR YWHAQ 0 900 0 901 1 1
DEPTOR HTT 0 0 218 223 1 2
DEPTOR TOR1A 0 0 0 218 1 1
DEPTOR EIF4E 0 0 602 611 1 2
DEPTOR ETV6 0 0 52 214 1 1
DEPTOR SLC2A1 0 0 161 161 1 2
DEPTOR NEDD8 0 0 261 274 1 2
DEPTOR LAMP1 0 0 146 153 1 2
DEPTOR SESN1 0 0 383 396 1 1
DEPTOR IRS1 0 0 470 491 1 2
DEPTOR SGK1 0 0 661 668 1 2
DEPTOR TP53 0 0 335 349 1 2
DEPTOR MDM2 0 0 213 213 1 2
DEPTOR DEPDC4 0 0 187 492 1 1
DEPTOR TRIM16 270 0 72 293 1 2
DEPTOR STAT3 0 0 212 212 1 2
DEPTOR C7orf60 0 0 167 167 1 1
DEPTOR EIF2AK4 0 0 215 215 1 2
DEPTOR MAP4K3 0 0 181 181 1 1
DEPTOR LAMTOR4 0 0 387 386 1 1
DEPTOR AATF 0 0 164 191 1 1
DEPTOR PDPK1 0 0 335 335 1 2
DEPTOR NPRL2 0 0 308 307 1 1
DEPTOR SZT2 0 0 157 164 1 1
DEPTOR DDIT4 0 0 594 599 1 2
DEPTOR FAM180A 0 0 125 166 1 1
DEPTOR RHEB 0 900 710 972 1 2
DEPTOR BCAT2 0 0 150 173 1 1
DEPTOR TLDC1 0 0 142 327 1 1
DEPTOR ZNF572 0 0 152 205 1 1
DEPTOR JAK2 0 0 81 383 1 2
DEPTOR SYCE1L 0 0 170 169 1 1
DEPTOR PIK3CA 0 0 283 282 1 2
DEPTOR WIPI2 0 0 138 155 1 2
DEPTOR ALS2CL 0 0 97 168 1 1
DEPTOR IGBP1 0 800 0 809 1 1
DEPTOR RICTOR 270 900 989 999 1 2
DEPTOR EEF2 0 0 268 274 1 2
DEPTOR FNIP2 0 0 183 183 1 1
DEPTOR PPARGC1A 0 0 287 286 1 2
DEPTOR TNF 0 0 146 168 1 2
DEPTOR SMARCD1 0 0 123 198 1 1
DEPTOR NBR1 0 0 146 169 1 2
DEPTOR LARS 0 0 325 354 1 1
DEPTOR IGF1R 0 0 234 234 1 2
DEPTOR SYT17 0 0 81 287 1 1
DEPTOR ILK 0 0 181 182 1 1
DEPTOR SLC1A5 0 0 171 189 1 1
DEPTOR PIK3R2 0 0 164 163 1 1
DEPTOR MYC 0 0 340 340 1 2
DEPTOR YRDC 0 0 0 298 1 1
DEPTOR RTKN 0 0 53 177 1 1
DEPTOR STK11 0 0 422 422 1 2
DEPTOR TCEANC2 0 0 150 214 1 1
DEPTOR IGF1 0 0 337 351 1 2
DEPTOR AKT2 0 900 292 926 1 2
DEPTOR ANAPC2 0 0 81 345 1 1
DEPTOR MAPK1 0 0 135 171 1 2
DEPTOR UVRAG 0 0 323 323 1 2
DEPTOR EIF2B5 0 0 107 168 1 1
DEPTOR CCND3 0 0 646 646 1 1
DEPTOR NEDD4L 0 0 138 157 1 1
DEPTOR FBXW8 0 0 241 263 1 1
DEPTOR RB1CC1 0 0 465 465 1 2
DEPTOR LARP1 0 0 181 196 1 1
DEPTOR VPS39 0 0 211 211 1 1
DEPTOR NGDN 0 0 413 421 1 1
DEPTOR RPS6KA2 0 0 318 317 1 1
DEPTOR EFNA5 0 0 395 394 1 1
DEPTOR ATG4B 0 0 194 202 1 2
DEPTOR TNFAIP3 270 0 0 270 1 2
DEPTOR LAMTOR3 0 0 334 338 1 1
DEPTOR BCAP31 0 0 64 207 1 1
DEPTOR RAB7A 0 0 218 218 1 2
DEPTOR DRAM1 0 0 166 165 1 2
DEPTOR DSCAML1 0 0 0 309 1 1
DEPTOR ITFG2 0 0 162 168 1 1
DEPTOR LAMTOR2 0 0 369 369 1 1
DEPTOR FKBP1C 0 0 124 178 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0070300 Molecular Function phosphatidic acid binding enables IDA
GO:0005515 Molecular Function protein binding enables IPI
GO:0004860 Molecular Function protein kinase inhibitor activity enables IDA
GO:0030291 Molecular Function protein serine/threonine kinase inhibitor activity enables IDA
GO:0035556 Biological Process intracellular signal transduction involved_in IEA
GO:0032007 Biological Process negative regulation of TOR signaling involved_in IMP
GO:1904262 Biological Process negative regulation of TORC1 signaling involved_in IBA
GO:1904262 Biological Process negative regulation of TORC1 signaling involved_in IDA
GO:1904262 Biological Process negative regulation of TORC1 signaling involved_in IGI
GO:1903940 Biological Process negative regulation of TORC2 signaling involved_in IBA
GO:1903940 Biological Process negative regulation of TORC2 signaling involved_in IDA
GO:1903940 Biological Process negative regulation of TORC2 signaling involved_in IGI
GO:0045792 Biological Process negative regulation of cell size involved_in IMP
GO:0006469 Biological Process negative regulation of protein kinase activity involved_in IBA
GO:0006469 Biological Process negative regulation of protein kinase activity involved_in IMP
GO:0010508 Biological Process positive regulation of autophagy involved_in IDA
GO:2001236 Biological Process regulation of extrinsic apoptotic signaling pathway involved_in IMP
GO:0005765 Cellular Component lysosomal membrane is_active_in IDA
Pathways
Name DB ID
Network map of SARS-CoV-2 signaling pathway (WP5115) WikiPathways WP5115_r124648
p53 transcriptional gene network (WP4963) WikiPathways WP4963_r122690
Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling (WP3850) WikiPathways WP3850_r121711
Fragile X syndrome (WP4549) WikiPathways WP4549_r124287
Clear cell renal cell carcinoma pathways (WP4018) WikiPathways WP4018_r123404
DYRK1A (WP5180) WikiPathways WP5180_r122423
Regulatory circuits of the STAT3 signaling pathway (WP4538) WikiPathways WP4538_r104390
Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway (WP4577) WikiPathways WP4577_r123500
Autophagy (WP4923) WikiPathways WP4923_r110416
Malignant pleural mesothelioma (WP5087) WikiPathways WP5087_r122659
T-cell activation SARS-CoV-2 (WP5098) WikiPathways WP5098_r119538
Transcripts
Accession Version MolecularType Name NCBI Comments
NM_022783 4 mRNA transcript variant 1 NC_000008 Reference
NM_001283012 2 mRNA transcript variant 2 NC_000008 Reference