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SYK

spleen associated tyrosine kinase
General Information
Name spleen associated tyrosine kinase
Alias
  • tyrosine-protein kinase SYK
  • spleen tyrosine kinase
Gene_family SH2 domain containing|Syk family tyrosine kinases
organism Homo sapiens
entrez_id 6850
location 9q22.2
transcript_count 9
exon_count 15
Location
by NCBI GRCh38.p14
Summary
    Entrez This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
    Stringdb Tyrosine-protein kinase SYK; Non-receptor tyrosine kinase which mediates signal transduction downstream of a variety of transmembrane receptors including classical immunoreceptors like the B-cell receptor (BCR). Regulates several biological processes including innate and adaptive immunity, cell adhesion, osteoclast maturation, platelet activation and vascular development. Assembles into signaling complexes with activated receptors at the plasma membrane via interaction between its SH2 domains and the receptor tyrosine- phosphorylated ITAM domains. The association with the receptor can [...]
    nextProt Non-receptor tyrosine kinase which mediates signal transduction downstream of a variety of transmembrane receptors including classical immunoreceptors like the B-cell receptor (BCR). Regulates several biological processes including innate and adaptive immunity, cell adhesion, osteoclast maturation, platelet activation and vascular development (PubMed:33782605). Assembles into signaling complexes with activated receptors at the plasma membrane via interaction between its SH2 domains and the receptor tyrosine-phosphorylated ITAM domains. The association with the receptor can also be indirect and mediated by adapter proteins containing ITAM or partial hemITAM domains. The phosphorylation of the ITAM domains is generally mediated by SRC subfamily kinases upon engagement of the receptor. More rarely signal transduction via SYK could be ITAM-independent. Direct downstream effectors phosphorylated by SYK include VAV1, PLCG1, PI-3-kinase, LCP2 and BLNK. Initially identified as essential in B-cell receptor (BCR) signaling, it is necessary for the maturation of B-cells most probably at the pro-B to pre-B transition. Activated upon BCR engagement, it phosphorylates and activates BLNK an adapter linking the activated BCR to downstream signaling adapters and effectors. It also phosphorylates and activates PLCG1 and the PKC signaling pathway. It also phosphorylates BTK and regulates its activity in B-cell antigen receptor (BCR)-coupled signaling. In addition to its function downstream of BCR also plays a role in T-cell receptor signaling. Plays also a crucial role in the innate immune response to fungal, bacterial and viral pathogens. It is for instance activated by the membrane lectin CLEC7A. Upon stimulation by fungal proteins, CLEC7A together with SYK activates immune cells inducing the production of ROS. Also activates the inflammasome and NF-kappa-B-mediated transcription of chemokines and cytokines in presence of pathogens. Regulates neutrophil degranulation and phagocytosis through activation of the MAPK signaling cascade (By similarity). Required for the stimulation of neutrophil phagocytosis by IL15 (PubMed:15123770). Also mediates the activation of dendritic cells by cell necrosis stimuli. Also involved in mast cells activation. Involved in interleukin-3/IL3-mediated signaling pathway in basophils (By similarity). Also functions downstream of receptors mediating cell adhesion. Relays for instance, integrin-mediated neutrophils and macrophages activation and P-selectin receptor/SELPG-mediated recruitment of leukocytes to inflammatory loci. Also plays a role in non-immune processes. It is for instance involved in vascular development where it may regulate blood and lymphatic vascular separation. It is also required for osteoclast development and function. Functions in the activation of platelets by collagen, mediating PLCG2 phosphorylation and activation. May be coupled to the collagen receptor by the ITAM domain-containing FCER1G. Also activated by the membrane lectin CLEC1B that is required for activation of platelets by PDPN/podoplanin. Involved in platelet adhesion being activated by ITGB3 engaged by fibrinogen. Together with CEACAM20, enhances production of the cytokine CXCL8/IL-8 via the NFKB pathway and may thus have a role in the intestinal immune response (By similarity).
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
SYK BioGRID NUFIP2 GeneID BioGRID Affinity Capture-MS
SYK BioGRID PLEKHD1 GeneID BioGRID Affinity Capture-MS
SYK BioGRID ZFC3H1 GeneID BioGRID Affinity Capture-MS
SYK BioGRID AFG2A GeneID BioGRID Affinity Capture-MS
SYK BioGRID PPP4R2 GeneID BioGRID Affinity Capture-MS
SYK BioGRID FTSJ3 GeneID BioGRID Affinity Capture-MS
SYK BioGRID OSBPL8 GeneID BioGRID Affinity Capture-MS
SYK BioGRID NAF1 GeneID BioGRID Affinity Capture-MS
SYK BioGRID MTDH GeneID BioGRID Affinity Capture-MS
SYK BioGRID DHX57 GeneID BioGRID Affinity Capture-MS
SYK BioGRID LTV1 GeneID BioGRID Affinity Capture-MS
SYK BioGRID TRMT1L GeneID BioGRID Affinity Capture-MS
SYK BioGRID DDX54 GeneID BioGRID Affinity Capture-MS
SYK BioGRID AFG2B GeneID BioGRID Affinity Capture-MS
SYK BioGRID C8orf33 GeneID BioGRID Affinity Capture-MS
SYK BioGRID KRI1 GeneID BioGRID Affinity Capture-MS
SYK BioGRID MRPS5 GeneID BioGRID Affinity Capture-MS
SYK BioGRID MRPS26 GeneID BioGRID Affinity Capture-MS
SYK BioGRID PPP4R3B GeneID BioGRID Affinity Capture-MS
SYK BioGRID DDX24 GeneID BioGRID Affinity Capture-MS
SYK BioGRID PPAN GeneID BioGRID Affinity Capture-MS
SYK BioGRID PPP2R2D GeneID BioGRID Affinity Capture-MS
SYK BioGRID TSR1 GeneID BioGRID Affinity Capture-MS
SYK BioGRID MAP7D1 GeneID BioGRID Affinity Capture-MS
SYK BioGRID PPP4R3A GeneID BioGRID Affinity Capture-MS
SYK BioGRID GTF3C3 GeneID BioGRID Affinity Capture-MS
SYK BioGRID GTF3C4 GeneID BioGRID Affinity Capture-MS
SYK BioGRID NOLC1 GeneID BioGRID Affinity Capture-MS
SYK BioGRID DDX18 GeneID BioGRID Affinity Capture-MS
SYK BioGRID PRKRA GeneID BioGRID Affinity Capture-MS
SYK BioGRID NUP214 GeneID BioGRID Affinity Capture-MS
SYK BioGRID TCOF1 GeneID BioGRID Affinity Capture-MS
SYK BioGRID SURF6 GeneID BioGRID Affinity Capture-MS
SYK BioGRID SRPK1 GeneID BioGRID Affinity Capture-MS
SYK BioGRID RPS15 GeneID BioGRID Affinity Capture-MS
SYK BioGRID RPL39 GeneID BioGRID Affinity Capture-MS
SYK BioGRID RFC2 GeneID BioGRID Affinity Capture-MS
SYK BioGRID PURB GeneID BioGRID Affinity Capture-MS
SYK BioGRID PURA GeneID BioGRID Affinity Capture-MS
SYK BioGRID PPP2R2A GeneID BioGRID Affinity Capture-MS
SYK BioGRID PPP2R1B GeneID BioGRID Affinity Capture-MS
SYK BioGRID PPP2R1A GeneID BioGRID Affinity Capture-MS
SYK BioGRID PPP2CA GeneID BioGRID Affinity Capture-MS
SYK BioGRID POLRMT GeneID BioGRID Affinity Capture-MS
SYK BioGRID EXOSC10 GeneID BioGRID Affinity Capture-MS
SYK BioGRID DDX27 GeneID BioGRID Affinity Capture-MS
SYK BioGRID LYAR GeneID BioGRID Affinity Capture-MS
SYK BioGRID PBRM1 GeneID BioGRID Affinity Capture-MS
SYK BioGRID SDAD1 GeneID BioGRID Affinity Capture-MS
SYK BioGRID RBM28 GeneID BioGRID Affinity Capture-MS
SYK BioGRID PTCD3 GeneID BioGRID Affinity Capture-MS
SYK BioGRID ZFR GeneID BioGRID Affinity Capture-MS
SYK BioGRID MRPS23 GeneID BioGRID Affinity Capture-MS
SYK BioGRID RRP15 GeneID BioGRID Affinity Capture-MS
SYK BioGRID EXOSC1 GeneID BioGRID Affinity Capture-MS
SYK BioGRID HP1BP3 GeneID BioGRID Affinity Capture-MS
SYK BioGRID NOP53 GeneID BioGRID Affinity Capture-MS
SYK BioGRID GNL2 GeneID BioGRID Affinity Capture-MS
SYK BioGRID USP25 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Two-hybrid
SYK BioGRID BABAM1 GeneID BioGRID Affinity Capture-MS
SYK BioGRID MRPS18B GeneID BioGRID Affinity Capture-MS
SYK BioGRID PELP1 GeneID BioGRID Affinity Capture-MS
SYK BioGRID GNL3 GeneID BioGRID Affinity Capture-MS
SYK BioGRID NOC2L GeneID BioGRID Affinity Capture-MS
SYK BioGRID GTPBP4 GeneID BioGRID Affinity Capture-MS
SYK BioGRID MTREX GeneID BioGRID Affinity Capture-MS
SYK BioGRID RRP8 GeneID BioGRID Affinity Capture-MS
SYK BioGRID LARP1 GeneID BioGRID Affinity Capture-MS
SYK BioGRID BOP1 GeneID BioGRID Affinity Capture-MS
SYK BioGRID RRP12 GeneID BioGRID Affinity Capture-MS
SYK BioGRID RRS1 GeneID BioGRID Affinity Capture-MS
SYK BioGRID ABRAXAS2 GeneID BioGRID Affinity Capture-MS
SYK BioGRID RRP1B GeneID BioGRID Affinity Capture-MS
SYK BioGRID RBM34 GeneID BioGRID Affinity Capture-MS
SYK BioGRID PDCD11 GeneID BioGRID Affinity Capture-MS
SYK BioGRID EXOSC8 GeneID BioGRID Affinity Capture-MS
SYK BioGRID CPSF6 GeneID BioGRID Affinity Capture-MS
SYK BioGRID EBNA1BP2 GeneID BioGRID Affinity Capture-MS
SYK BioGRID POP1 GeneID BioGRID Affinity Capture-MS
SYK BioGRID CTCF GeneID BioGRID Affinity Capture-MS
SYK BioGRID RACK1 GeneID BioGRID Affinity Capture-MS
SYK BioGRID MRPS31 GeneID BioGRID Affinity Capture-MS
SYK BioGRID CEBPZ GeneID BioGRID Affinity Capture-MS
SYK BioGRID SART3 GeneID BioGRID Affinity Capture-MS
SYK BioGRID BABAM2 GeneID BioGRID Affinity Capture-MS
SYK BioGRID MOV10 GeneID BioGRID Affinity Capture-MS
SYK BioGRID HADHB GeneID BioGRID Affinity Capture-MS
SYK BioGRID HADHA GeneID BioGRID Affinity Capture-MS
SYK BioGRID HSD17B10 GeneID BioGRID Affinity Capture-MS
SYK BioGRID GTF3C1 GeneID BioGRID Affinity Capture-MS
SYK BioGRID GRSF1 GeneID BioGRID Affinity Capture-MS
SYK BioGRID GLG1 GeneID BioGRID Affinity Capture-MS
SYK BioGRID FMR1 GeneID BioGRID Affinity Capture-MS
SYK BioGRID DDX1 GeneID BioGRID Affinity Capture-MS
SYK BioGRID CRYAA GeneID BioGRID Reconstituted Complex
SYK BioGRID ALCAM GeneID BioGRID Co-fractionation
SYK BioGRID PTPN6 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
SYK BioGRID CLEC7A GeneID BioGRID Affinity Capture-Western
SYK BioGRID TRIM31 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
SYK BioGRID FCER1G GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SYK BioGRID EP300 GeneID BioGRID Affinity Capture-MS
SYK BioGRID BTF3 GeneID BioGRID Affinity Capture-MS
SYK BioGRID EBNA-1 GeneID BioGRID Affinity Capture-MS
SYK BioGRID INS GeneID BioGRID Affinity Capture-MS
SYK BioGRID AR GeneID BioGRID Reconstituted Complex
SYK BioGRID MET GeneID BioGRID Reconstituted Complex
SYK BioGRID KIT GeneID BioGRID Reconstituted Complex
SYK BioGRID GAB1 GeneID BioGRID Reconstituted Complex
SYK BioGRID ERBB4 GeneID BioGRID Protein-peptide; Reconstituted Complex
SYK BioGRID ERBB3 GeneID BioGRID Protein-peptide; Reconstituted Complex
SYK BioGRID ERBB2 GeneID BioGRID Protein-peptide; Reconstituted Complex
SYK BioGRID EGFR GeneID BioGRID Protein-peptide; Reconstituted Complex
SYK BioGRID NHLRC2 GeneID BioGRID Proximity Label-MS
SYK BioGRID STAT3 GeneID BioGRID Two-hybrid
SYK BioGRID BRD7 GeneID BioGRID Affinity Capture-MS
SYK BioGRID TP53 GeneID BioGRID Affinity Capture-MS
SYK BioGRID PLEKHA4 GeneID BioGRID Affinity Capture-MS
SYK BioGRID CBL GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Co-localization; Reconstituted Complex
SYK BioGRID ABCF1 GeneID BioGRID Affinity Capture-Western
SYK BioGRID ATG16L1 GeneID BioGRID Affinity Capture-MS
SYK BioGRID COASY GeneID BioGRID Biochemical Activity
SYK BioGRID PIK3AP1 GeneID BioGRID Affinity Capture-Western
SYK BioGRID DPP9 GeneID BioGRID Biochemical Activity; Co-localization; Reconstituted Complex
SYK BioGRID FLNA GeneID BioGRID Co-localization
SYK BioGRID TAMALIN GeneID BioGRID Affinity Capture-Western
SYK BioGRID GRM1 GeneID BioGRID Affinity Capture-Western
SYK BioGRID SRC GeneID BioGRID Affinity Capture-Western; Biochemical Activity
SYK BioGRID CBLB GeneID BioGRID Affinity Capture-Western; Biochemical Activity
SYK BioGRID HGS GeneID BioGRID Biochemical Activity
SYK BioGRID RHOU GeneID BioGRID Reconstituted Complex
SYK BioGRID TNFRSF1A GeneID BioGRID Affinity Capture-Western
SYK BioGRID CTTN GeneID BioGRID Affinity Capture-Western; Co-localization
SYK BioGRID TRIM15 GeneID BioGRID PCA
SYK BioGRID HCLS1 GeneID BioGRID Co-localization
SYK BioGRID FCGR1A GeneID BioGRID Co-localization
SYK BioGRID TENT5A GeneID BioGRID Affinity Capture-Luminescence; Two-hybrid
SYK BioGRID PEAR1 GeneID BioGRID Affinity Capture-Western
SYK BioGRID MEGF10 GeneID BioGRID Affinity Capture-Western
SYK BioGRID SH2D2A GeneID BioGRID Two-hybrid
SYK BioGRID TRAF6 GeneID BioGRID Affinity Capture-Western
SYK BioGRID IL17RA GeneID BioGRID Affinity Capture-Western
SYK BioGRID TRAF3IP2 GeneID BioGRID Affinity Capture-Western
SYK BioGRID PTPRO GeneID BioGRID Affinity Capture-Western
SYK BioGRID FCGR3A GeneID BioGRID Affinity Capture-Western; Biochemical Activity
SYK BioGRID TICAM1 GeneID BioGRID Affinity Capture-Western
SYK BioGRID TLR9 GeneID BioGRID Affinity Capture-Western
SYK BioGRID TBK1 GeneID BioGRID Affinity Capture-Western
SYK BioGRID TRAF3 GeneID BioGRID Affinity Capture-Western
SYK BioGRID TLR4 GeneID BioGRID Affinity Capture-Western
SYK BioGRID TLR3 GeneID BioGRID Affinity Capture-Western
SYK BioGRID MAP3K7 GeneID BioGRID Affinity Capture-Western
SYK BioGRID MYD88 GeneID BioGRID Affinity Capture-Western
SYK BioGRID SYK GeneID BioGRID Biochemical Activity; Co-crystal Structure
SYK BioGRID UBASH3B GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
SYK BioGRID VCAM1 GeneID BioGRID Affinity Capture-MS
SYK BioGRID ITGA4 GeneID BioGRID Affinity Capture-MS
SYK BioGRID APP GeneID BioGRID Reconstituted Complex
SYK BioGRID SH3BP2 GeneID BioGRID Affinity Capture-Western; Two-hybrid
SYK BioGRID MAPT GeneID BioGRID Affinity Capture-Western; Biochemical Activity
SYK BioGRID TUBB GeneID BioGRID Affinity Capture-Western
SYK BioGRID VAV2 GeneID BioGRID Two-hybrid
SYK BioGRID VAV1 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex; Two-hybrid
SYK BioGRID PIK3CG GeneID BioGRID Affinity Capture-Western
SYK BioGRID BLNK GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
SYK BioGRID BTK GeneID BioGRID Affinity Capture-Western
SYK BioGRID PIK3R1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SYK BioGRID TRAIP GeneID BioGRID Affinity Capture-Western; Two-hybrid
SYK BioGRID KLRA1P GeneID BioGRID Affinity Capture-Western
SYK BioGRID SEC23B GeneID BioGRID Affinity Capture-MS
SYK BioGRID GRAP2 GeneID BioGRID Affinity Capture-MS
SYK BioGRID TYROBP GeneID BioGRID Reconstituted Complex
SYK BioGRID TERF1 GeneID BioGRID Two-hybrid
SYK BioGRID SLC4A1 GeneID BioGRID Biochemical Activity
SYK BioGRID RPS10 GeneID BioGRID Two-hybrid
SYK BioGRID PIK3R2 GeneID BioGRID Two-hybrid
SYK BioGRID NCK1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
SYK BioGRID LCP2 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
SYK BioGRID LCK GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SYK BioGRID ITGB3 GeneID BioGRID Affinity Capture-Western
SYK BioGRID INPP5D GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
SYK BioGRID GRB2 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
SYK BioGRID FGR GeneID BioGRID Affinity Capture-Western; Two-hybrid
SYK BioGRID FCER1A GeneID BioGRID Affinity Capture-Western
SYK BioGRID NEDD4 GeneID BioGRID Reconstituted Complex
SYK BioGRID TUBG1 GeneID BioGRID Affinity Capture-Western; Co-fractionation
SYK BioGRID Cbl GeneID BioGRID Affinity Capture-Western
SYK BioGRID CALM1 GeneID BioGRID Biochemical Activity
SYK BioGRID HDAC6 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
SYK BioGRID HDAC4 GeneID BioGRID Reconstituted Complex
SYK BioGRID HDAC9 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
SYK BioGRID HDAC3 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
SYK BioGRID SP1 GeneID BioGRID Affinity Capture-Western
SYK BioGRID HDAC2 GeneID BioGRID Reconstituted Complex
SYK BioGRID HDAC1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
SYK Protein NFAM1 GeneID HPRD
SYK Protein SH2B2 GeneID HPRD
SYK Protein CD3E GeneID HPRD
SYK Protein LAX1 GeneID HPRD
SYK Protein UBB GeneID HPRD
SYK Protein DBNL GeneID HPRD
SYK Protein PIK3AP1 GeneID HPRD
SYK Protein GAB2 GeneID HPRD
SYK Protein PAG1 GeneID HPRD
SYK Protein PRKD1 GeneID HPRD
SYK Protein SIT1 GeneID HPRD
SYK Protein BLNK GeneID HPRD
SYK Protein CBLB GeneID HPRD
SYK Protein TYROBP GeneID HPRD
SYK Protein PIK3R2 GeneID HPRD
SYK Protein TLR4 GeneID HPRD
SYK Protein HNRNPU GeneID HPRD
SYK Protein TUBA1A GeneID HPRD
SYK Protein PXN GeneID HPRD
SYK Protein TRAF6 GeneID HPRD
SYK Protein LAT GeneID HPRD
SYK Protein SH3BP2 GeneID HPRD
SYK Protein CRKL GeneID HPRD
SYK Protein MAP4K1 GeneID HPRD
SYK Protein MAPK3 GeneID HPRD
SYK Protein RPS6KA1 GeneID HPRD
SYK Protein LCP2 GeneID HPRD
SYK Protein STAT5A GeneID HPRD
SYK Protein HCLS1 GeneID HPRD
SYK Protein PTK2B GeneID HPRD
SYK Protein POU2AF1 GeneID HPRD
SYK Protein SLA GeneID HPRD
SYK Protein PTK2 GeneID HPRD
SYK Protein SELPLG GeneID HPRD
SYK Protein SHC1 GeneID HPRD
SYK Protein STAT1 GeneID HPRD
SYK Protein VAV2 GeneID HPRD
SYK Protein PLCG2 GeneID HPRD
SYK Protein DUSP3 GeneID HPRD
SYK Protein SYK GeneID HPRD
SYK Protein ITGB2 GeneID HPRD
SYK Protein BTK GeneID HPRD
SYK Protein TNFRSF1A GeneID HPRD
SYK Protein TUBA4A GeneID HPRD
SYK Protein SRC GeneID HPRD
SYK Protein PRKCA GeneID HPRD
SYK Protein PTPN6 GeneID HPRD
SYK Protein PLCG1 GeneID HPRD
SYK Protein PIK3R1 GeneID HPRD
SYK Protein CBL GeneID HPRD
SYK Protein LYN GeneID HPRD
SYK Protein FGR GeneID HPRD
SYK Protein VAV1 GeneID HPRD
SYK Protein CTTN GeneID HPRD
SYK Protein SNCA GeneID HPRD
SYK Protein LCK GeneID HPRD
SYK Protein JAK1 GeneID HPRD
SYK Protein CD79B GeneID HPRD
SYK Protein FCER1G GeneID HPRD
SYK Protein MS4A2 GeneID HPRD
SYK Protein FCGR2A GeneID HPRD
SYK Protein FCGR1A GeneID HPRD
SYK Protein IL2RB GeneID HPRD
SYK Protein RASA1 GeneID HPRD
SYK Protein CSF2RB GeneID HPRD
SYK Protein CSF3R GeneID HPRD
SYK Protein FYN GeneID HPRD
SYK Protein EPOR GeneID HPRD
SYK Protein CD79A GeneID HPRD
SYK Protein SLC4A1 GeneID HPRD
SYK Protein GRB2 GeneID HPRD
SYK Protein CD22 GeneID HPRD
SYK Protein CD19 GeneID HPRD
SYK Protein STAT3 GeneID HPRD
SYK BioGRID FCGR2A GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
SYK BioGRID CSF3R GeneID BioGRID Affinity Capture-Western
SYK BioGRID CD4 GeneID BioGRID Affinity Capture-Western
SYK BioGRID FCRL3 GeneID BioGRID Reconstituted Complex
SYK BioGRID SIT1 GeneID BioGRID Affinity Capture-Western
SYK BioGRID FYN GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
SYK BioGRID EPOR GeneID BioGRID Affinity Capture-Luminescence
SYK BioGRID CD22 GeneID BioGRID Affinity Capture-Western
SYK BioGRID PAG1 GeneID BioGRID Reconstituted Complex
SYK BioGRID LAT GeneID BioGRID Biochemical Activity
SYK BioGRID SIRPB1 GeneID BioGRID Affinity Capture-Western
SYK BioGRID TUBA1A GeneID BioGRID Biochemical Activity
SYK BioGRID SLA GeneID BioGRID Affinity Capture-Western
SYK BioGRID RPS6KB2 GeneID BioGRID Biochemical Activity
SYK BioGRID RPS6KB1 GeneID BioGRID Biochemical Activity
SYK BioGRID PXN GeneID BioGRID Affinity Capture-Western
SYK BioGRID PTK2 GeneID BioGRID Affinity Capture-Western
SYK BioGRID PRKD1 GeneID BioGRID Affinity Capture-Western
SYK BioGRID PLCG2 GeneID BioGRID Affinity Capture-Western
SYK BioGRID PLCG1 GeneID BioGRID Affinity Capture-Western
SYK BioGRID ITGB2 GeneID BioGRID Affinity Capture-Western
SYK BioGRID MS4A2 GeneID BioGRID Reconstituted Complex
SYK BioGRID CRKL GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
SYK BioGRID CD79A GeneID BioGRID Reconstituted Complex
SYK BioGRID CD72 GeneID BioGRID Biochemical Activity
SYK BioGRID CD19 GeneID BioGRID Affinity Capture-Western
SYK BioGRID CD3E GeneID BioGRID Reconstituted Complex
SYK BioGRID LYN GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
SYK BioGRID PTK2B GeneID BioGRID Affinity Capture-Western
SYK BioGRID CD79B GeneID BioGRID Reconstituted Complex
SYK Protein EZR GeneID BIND Syk interacts with ezrin. This interaction was modeled on a demonstrated interaction between Syk and ezrin from unspecified species.
SYK Protein MSN GeneID BIND Syk interacts with moesin. This interaction was modeled on a demonstrated interaction between Syk and moesin from unspecified species.
SYK Protein SYK GeneID BIND SYK autophosphorylates.
SYK Protein STAT1 GeneID BIND Syk interacts with STAT1-beta.
SYK Protein STAT1 GeneID BIND Syk interacts with and phosphorylates STAT1-alpha.
SYK Protein CRKL GeneID BIND CrkL interacts with Syk.
SYK Protein HHV4gp002 GeneID BIND Epstein-Barr virus LMP2A interacts with Syk.
SYK Protein UBB GeneID BIND Syk interacts with ubiquitin.
StringDB
A B experiments database textmining combined score hadb nhadb
SYK EFNB2 0 0 113 249 1 1
SYK CCL20 0 0 235 235 1 1
SYK MCTP2 0 0 66 588 1 1
SYK FMN1 0 0 181 295 1 1
SYK CXCR6 0 0 123 175 1 1
SYK GRK6 0 0 55 154 1 1
SYK NCK1 270 500 470 819 1 1
SYK RBPJ 0 0 134 198 1 1
SYK CXCL2 0 0 324 338 1 1
SYK ITGB4 0 0 466 483 1 1
SYK LPHN1 0 0 47 191 1 1
SYK PARVG 0 0 0 228 1 1
SYK CDH11 0 0 157 171 1 1
SYK ATG7 0 0 134 150 1 2
SYK SELE 0 0 324 335 1 1
SYK TJP1 0 0 122 228 1 1
SYK TGFBR2 0 0 134 205 1 1
SYK TRAT1 0 900 194 921 1 1
SYK ACTG1 0 0 146 245 1 1
SYK WDR7 0 0 0 188 1 1
SYK ITGB5 0 0 127 153 1 1
SYK IKZF1 0 0 298 446 1 1
SYK ICAM3 0 0 291 311 1 1
SYK RET 0 0 235 181 1 1
SYK ENSG00000267261 0 0 0 178 1 1
SYK GPR174 0 0 0 203 1 1
SYK GNAI1 0 0 81 205 1 1
SYK AXIN1 0 0 81 167 1 1
SYK IDH2 0 0 181 181 1 1
SYK IL23A 0 0 321 321 1 1
SYK PREB 0 0 155 207 1 1
SYK PLEKHG4B 0 0 0 165 1 1
SYK FERMT2 0 0 135 171 1 1
SYK ITGA2B 0 600 340 744 1 1
SYK EZR 0 0 552 568 1 1
SYK SHC1 459 900 558 975 1 1
SYK THBD 0 0 183 183 1 1
SYK ATM 0 0 293 305 1 2
SYK SFRP1 0 0 158 182 1 1
SYK TIMP3 0 0 193 207 1 1
SYK CD226 0 0 289 321 1 1
SYK MAPK14 0 900 424 931 1 2
SYK SH3BP1 0 0 0 164 1 1
SYK CSF3R 270 0 758 841 1 1
SYK CFL1 0 0 287 330 1 1
SYK LPXN 0 0 122 187 1 1
SYK MGEA5 0 0 464 467 1 1
SYK FAM134B 0 0 53 200 1 1
SYK MAPK10 0 0 193 186 1 2
SYK WT1 0 0 112 178 1 1
SYK CLIC4 0 0 0 159 1 1
SYK MAP3K3 0 0 159 151 1 1
SYK EFHD2 0 0 375 399 1 1
SYK BMP4 0 0 67 173 1 1
SYK ZC3H12A 0 0 101 157 1 1
SYK ASAP2 0 0 0 165 1 1
SYK ATAD2B 0 0 0 153 1 1
SYK S1PR1 0 0 137 183 1 1
SYK NFKBIA 0 900 519 955 1 2
SYK VILL 0 0 51 157 1 1
SYK FCER1G 675 900 988 999 1 1
SYK SLC7A7 0 0 0 282 1 1
SYK CASP5 0 0 155 297 1 1
SYK TRAF7 0 0 113 235 1 1
SYK PRKAA2 0 0 66 167 1 2
SYK STXBP5L 0 0 0 167 1 1
SYK MAPK7 0 0 181 209 1 1
SYK IRF4 0 0 408 456 1 1
SYK LRR1 0 0 63 171 1 1
SYK VEGFA 0 0 341 341 1 2
SYK SIGLEC8 0 0 218 245 1 1
SYK PTEN 0 0 456 499 1 2
SYK TREML4 0 0 173 229 1 1
SYK STX11 0 0 120 183 1 1
SYK ID3 0 0 155 154 1 1
SYK MBP 0 0 143 156 1 2
SYK SCARF1 0 0 150 220 1 1
SYK XBP1 0 0 176 197 1 2
SYK STAT2 0 0 195 310 1 1
SYK GIT1 0 0 112 233 1 1
SYK HLA-C 0 0 205 240 1 1
SYK SASH3 0 0 0 244 1 1
SYK PTPN1 0 0 299 342 1 1
SYK MPL 0 0 441 455 1 1
SYK PPP5D1 0 0 0 150 1 1
SYK NLRP14 0 0 122 202 1 1
SYK LAPTM5 0 0 62 294 1 1
SYK ATG5 0 0 178 193 1 2
SYK CYTH1 0 0 101 167 1 1
SYK ITGB3 270 900 914 993 1 1
SYK TLR8 0 0 342 471 1 1
SYK GNA11 0 0 97 226 1 1
SYK TUBB 270 0 97 333 1 1
SYK RGS1 0 0 57 244 1 1
SYK GATA2 0 0 171 302 1 1
SYK ITGAM 0 0 527 648 1 1
SYK MAP3K5 0 0 203 273 1 1
SYK ACKR2 0 0 141 154 1 1
SYK MAPK6 0 0 0 154 1 1
SYK TSPAN33 0 0 59 166 1 1
SYK PPP1CA 117 0 75 254 1 1
SYK IRF5 0 0 300 404 1 1
SYK RAC1 94 900 372 945 1 2
SYK HMGB1 0 0 233 264 1 2
SYK CTSK 0 0 323 335 1 2
SYK LYN 462 900 989 967 1 1
SYK CST7 0 0 155 312 1 1
SYK BCOR 0 0 194 194 1 1
SYK SPI1 0 0 369 535 1 1
SYK NOX1 0 0 144 204 1 1
SYK CTSB 0 0 295 323 1 2
SYK MCL1 0 0 419 431 1 2
SYK GMIP 0 0 0 169 1 1
SYK CR1 0 0 141 233 1 1
SYK CCR7 0 0 323 376 1 1
SYK IKBKG 0 0 314 326 1 1
SYK VTN 0 0 284 284 1 1
SYK C1QC 0 0 107 198 1 1
SYK PARD6B 0 0 0 189 1 1
SYK RALA 0 0 81 195 1 1
SYK CXCR5 0 0 335 361 1 1
SYK NEK2 0 0 107 175 1 1
SYK LILRB3 0 600 349 748 1 1
SYK RPS6KA1 213 0 260 388 1 1
SYK PACSIN2 0 0 0 156 1 1
SYK THPO 0 0 202 202 1 1
SYK NCAM1 0 0 299 345 1 1
SYK RASL10A 0 0 74 187 1 1
SYK TBX21 0 0 284 340 1 1
SYK MYO1F 0 0 442 577 1 1
SYK WDFY4 0 0 0 354 1 1
SYK ISG15 0 0 113 187 1 2
SYK ADAM17 0 0 206 223 1 1
SYK NFKBIB 0 0 154 253 1 1
SYK SERPINB8 0 0 0 248 1 1
SYK SOCS6 0 0 162 241 1 1
SYK ANXA6 0 0 399 399 1 1
SYK CEACAM4 0 0 61 169 1 1
SYK CMA1 0 0 210 247 1 1
SYK ANO6 0 0 124 156 1 1
SYK DYRK1A 0 0 203 274 1 1
SYK HSPB1 0 0 125 171 1 2
SYK ENSG00000255819 0 0 469 513 1 1
SYK GLI1 0 0 46 150 1 2
SYK FOS 0 900 420 941 1 2
SYK S100A8 0 0 81 187 1 2
SYK YWHAZ 0 0 137 248 1 1
SYK PPM1N 0 0 0 198 1 1
SYK GNGT2 0 0 67 151 1 1
SYK CLEC9A 0 0 716 735 1 1
SYK IL15RA 213 0 90 253 1 1
SYK GAB1 128 0 95 300 1 1
SYK LMO2 0 0 135 202 1 1
SYK RAB11B 0 0 0 174 1 1
SYK CRKL 270 650 407 862 1 1
SYK SHB 0 0 193 210 1 1
SYK FCER1A 270 900 398 958 1 1
SYK MCTP1 0 0 0 261 1 1
SYK PTPN11 0 900 680 934 1 1
SYK IRAK3 0 0 162 322 1 1
SYK NRAS 0 800 211 857 1 1
SYK HSPA5 0 0 96 363 1 2
SYK ARHGEF1 0 0 157 214 1 1
SYK FCRL6 0 0 90 171 1 1
SYK BTRC 0 0 67 157 1 1
SYK ARHGAP44 0 0 139 310 1 1
SYK CAMK4 0 0 282 196 1 1
SYK FKBP10 0 0 0 153 1 1
SYK DUSP3 213 0 181 381 1 1
SYK ADRBK1 0 0 113 187 1 1
SYK FOXO1 0 0 298 354 1 2
SYK SIGLEC15 0 0 372 384 1 1
SYK IFNGR1 0 0 112 193 1 1
SYK CCL17 0 0 213 213 1 1
SYK TUSC3 0 0 0 152 1 1
SYK CCL7 0 0 150 240 1 1
SYK SDC1 0 0 293 293 1 1
SYK WEE1 0 0 104 212 1 1
SYK NFAM1 213 0 517 682 1 1
SYK ARF6 0 0 250 470 1 1
SYK SF3B3 0 0 229 250 1 1
SYK ANKRD45 0 0 0 221 1 1
SYK PRKCH 0 0 71 174 1 1
SYK PIM3 0 0 66 199 1 1
SYK LILRA4 0 600 390 763 1 1
SYK PMAIP1 0 0 167 180 1 2
SYK TLR2 0 0 711 793 1 2
SYK PIK3CB 0 900 391 942 1 1
SYK CDKN2B 0 0 160 229 1 1
SYK LRRK2 0 0 135 224 1 2
SYK GNAO1 0 0 0 171 1 1
SYK MET 128 0 234 219 1 2
SYK TRAF3 270 0 646 765 1 2
SYK PHB 0 0 944 945 1 1
SYK GSTM2 0 0 57 214 1 1
SYK RASL10B 0 0 45 202 1 1
SYK WAS 0 0 460 600 1 1
SYK CD86 0 0 504 603 1 1
SYK FCN1 0 0 54 187 1 1
SYK ENSG00000277117 0 0 202 239 1 1
SYK FKBP9 0 0 0 153 1 1
SYK GNAI3 0 0 0 171 1 2
SYK NOD1 0 0 298 314 1 2
SYK UGP2 0 0 0 162 1 1
SYK ARHGAP35 0 0 113 178 1 1
SYK CLIC1 0 0 0 151 1 1
SYK TRIB3 0 0 0 162 1 2
SYK CXCL1 0 0 369 382 1 2
SYK IL33 0 0 325 325 1 2
SYK GNA15 0 0 56 247 1 1
SYK HSPA1B 62 0 0 159 1 1
SYK LNX1 0 0 0 200 1 1
SYK RPS6KC1 0 0 47 168 1 1
SYK FIGF 0 0 143 196 1 1
SYK CMTM2 0 0 90 164 1 1
SYK LIMK1 0 0 113 182 1 1
SYK PGLYRP1 0 0 108 152 1 1
SYK CCL11 0 0 181 200 1 1
SYK PSMB9 0 0 435 467 1 1
SYK AICDA 0 0 286 309 1 1
SYK CLEC4M 0 0 195 239 1 1
SYK BCAR1 0 900 248 922 1 1
SYK ALOX5 0 0 251 426 1 1
SYK HEATR6 0 0 0 288 1 1
SYK NOTCH2 0 0 166 217 1 1
SYK LIMS1 0 0 112 158 1 1
SYK NCAPG 0 0 0 519 1 1
SYK PRKCQ 0 0 307 261 1 2
SYK CD5 0 0 478 517 1 1
SYK CD28 0 900 505 953 1 1
SYK MIEN1 0 0 451 451 1 1
SYK GRM1 270 0 0 308 1 1
SYK CXCL5 0 0 142 226 1 1
SYK DIRAS3 0 0 101 193 1 2
SYK SFN 0 0 122 235 1 2
SYK SOCS2 0 0 210 282 1 1
SYK PTPN12 0 0 234 346 1 1
SYK CASP4 0 0 82 216 1 2
SYK ITGAX 0 0 456 560 1 1
SYK BLK 0 900 640 921 1 1
SYK SLC11A1 0 0 90 254 1 1
SYK ST14 0 0 0 152 1 1
SYK SAMHD1 0 0 123 327 1 1
SYK WNT2 0 0 0 165 1 1
SYK S100A12 0 0 73 153 1 1
SYK STAM 0 0 113 180 1 1
SYK SH2D1A 0 0 260 302 1 1
SYK KLF2 0 0 103 172 1 1
SYK CUL3 0 0 95 174 1 2
SYK CHUK 0 0 419 244 1 1
SYK HCK 0 900 814 942 1 1
SYK FCRLB 0 0 260 271 1 1
SYK ZNF24 129 0 0 164 1 1
SYK UBE2L6 0 0 57 203 1 1
SYK YWHAH 0 0 55 177 1 1
SYK TRPV5 0 0 74 337 1 1
SYK EGFLAM 0 0 0 177 1 1
SYK CSF1 0 0 459 558 1 1
SYK HDAC1 270 0 425 579 1 2
SYK PRDM1 0 0 322 347 1 1
SYK EWSR1 0 0 108 163 1 1
SYK SERPINB3 0 0 0 167 1 1
SYK P2RY13 0 0 71 164 1 1
SYK SERPINB7 0 0 0 248 1 1
SYK FCRL5 0 0 279 577 1 1
SYK RASA3 0 0 73 157 1 1
SYK TXNDC9 0 0 302 334 1 1
SYK RGS18 0 0 216 396 1 1
SYK CD52 0 0 214 369 1 1
SYK DBNL 213 0 503 604 1 1
SYK ARHGAP27 0 0 0 181 1 1
SYK HEXA 0 0 0 303 1 1
SYK CD93 0 0 150 256 1 1
SYK CD180 0 0 124 262 1 1
SYK TLR3 270 0 459 608 1 2
SYK CDKN3 0 0 87 159 1 1
SYK BIRC6 0 0 44 158 1 1
SYK CORO1A 0 0 147 316 1 1
SYK MIF 0 0 164 178 1 2
SYK CDC42 0 650 518 846 1 2
SYK RAG1 0 0 392 399 1 1
SYK F2 0 0 42 312 1 1
SYK LRP8 0 0 90 305 1 1
SYK IRF8 0 0 322 462 1 1
SYK UAP1L1 0 0 0 162 1 1
SYK CD3G 0 900 325 933 1 1
SYK APOE 0 0 253 252 1 2
SYK FMNL1 0 0 82 206 1 1
SYK FOXO3 0 0 181 246 1 2
SYK TNFSF11 0 0 459 462 1 2
SYK PRKCD 0 0 662 417 1 2
SYK MAP3K6 0 0 0 168 1 1
SYK RIPK3 0 0 167 217 1 2
SYK LRIT3 0 0 0 165 1 1
SYK STAT5B 0 900 504 954 1 1
SYK RAB7B 0 0 157 286 1 1
SYK PIK3C2A 0 0 82 166 1 1
SYK TGFB1 0 0 112 278 1 2
SYK RASSF5 0 0 218 264 1 1
SYK IKZF2 0 0 150 214 1 1
SYK TIAM1 0 0 134 183 1 1
SYK ALG2 0 0 0 157 1 1
SYK KDR 0 0 310 219 1 2
SYK PARD6G 0 0 0 189 1 1
SYK PACSIN1 0 0 49 223 1 1
SYK YY1 0 0 188 222 1 1
SYK RAB11A 0 0 142 310 1 2
SYK RAC2 0 650 464 846 1 1
SYK LILRA2 0 600 172 677 1 1
SYK KLRB1 0 0 260 334 1 1
SYK PRDM2 0 0 161 181 1 1
SYK TBK1 270 0 341 449 1 2
SYK CORO2A 0 0 0 170 1 1
SYK CLEC5A 0 0 732 757 1 1
SYK FGA 0 600 52 635 1 1
SYK FOXP3 0 0 373 423 1 2
SYK LAT2 0 900 601 964 1 1
SYK PTPN6 865 900 689 996 1 1
SYK KMT2D 0 0 127 151 1 1
SYK SHC2 0 800 90 830 1 1
SYK E2F4 0 0 73 161 1 1
SYK KIR2DL3 0 0 283 312 1 1
SYK TNKS2 0 0 81 189 1 1
SYK BMX 0 0 470 183 1 1
SYK NLRC4 0 0 408 477 1 2
SYK TPT1 0 0 161 222 1 1
SYK SSH2 0 0 0 156 1 1
SYK SLC2A5 0 0 0 161 1 1
SYK DUOX1 0 0 162 227 1 1
SYK CD247 0 900 722 975 1 1
SYK IGHV3-15 0 360 0 360 1 1
SYK ATP7A 0 0 284 367 1 1
SYK ATP2A3 0 0 56 161 1 1
SYK INPP5D 270 0 556 543 1 1
SYK SLC30A5 0 0 90 185 1 1
SYK VCAM1 94 0 323 377 1 1
SYK MAP3K15 0 0 0 182 1 1
SYK FAS 0 900 268 928 1 2
SYK CSF2 0 900 518 950 1 1
SYK EFNB3 0 0 0 168 1 1
SYK TMEM68 0 0 62 559 1 1
SYK SPIB 0 0 386 420 1 1
SYK WEE2 0 0 0 157 1 1
SYK YES1 0 900 507 915 1 1
SYK GPLD1 0 0 386 407 1 1
SYK NGF 0 0 151 176 1 2
SYK DDR1 0 0 263 162 1 1
SYK CD34 0 0 324 328 1 2
SYK DHODH 0 0 89 216 1 1
SYK PPM1E 0 0 0 198 1 1
SYK PIK3R6 0 900 113 918 1 1
SYK GRK5 0 0 74 161 1 1
SYK IMPAD1 0 0 0 537 1 1
SYK GPR183 0 0 108 240 1 1
SYK TNFSF8 0 0 137 196 1 1
SYK LTB4R 0 0 210 256 1 1
SYK MGAM 0 0 49 159 1 1
SYK CYLD 0 0 181 204 1 1
SYK EIF4EBP1 0 0 251 308 1 2
SYK USP25 854 0 697 955 1 1
SYK FOXO4 0 0 81 154 1 1
SYK AXL 0 0 603 249 1 2
SYK HSP90AB1 0 0 54 224 1 2
SYK GRM5 0 0 46 167 1 1
SYK BCL6 0 900 426 942 1 1
SYK MAG 0 0 74 196 1 1
SYK PPP3CA 0 0 103 209 1 1
SYK CD58 0 0 201 295 1 1
SYK ST6GALNAC2 0 0 0 206 1 1
SYK GPT 0 0 125 158 1 1
SYK ITPKC 0 0 74 153 1 1
SYK GDF1 0 0 0 156 1 1
SYK PDE5A 0 0 90 199 1 1
SYK EFNA3 0 0 0 168 1 1
SYK CCND3 0 0 236 236 1 1
SYK SLAMF8 0 0 71 168 1 1
SYK SOCS1 0 0 499 537 1 1
SYK BTK 462 900 982 973 1 1
SYK MAPK1 0 0 372 271 1 2
SYK IGF1 0 0 212 212 1 2
SYK CYTH3 0 0 103 151 1 1
SYK CSF1R 0 0 460 413 1 1
SYK CD6 0 0 125 262 1 1
SYK GBP5 0 0 112 188 1 1
SYK PKM 128 0 57 205 1 1
SYK RPS10 192 0 45 214 1 1
SYK BCL2A1 0 0 247 309 1 1
SYK KMT2A 0 0 164 187 1 1
SYK PLEKHA4 270 0 0 270 1 1
SYK SLAMF9 0 0 112 157 1 1
SYK GCSAM 0 0 378 401 1 1
SYK FGF2 0 0 171 171 1 2
SYK PPEF2 0 0 0 205 1 1
SYK RELB 0 0 341 355 1 2
SYK ITSN2 0 0 75 257 1 1
SYK PPTC7 0 0 0 198 1 1
SYK SOS1 0 900 325 938 1 1
SYK CD2AP 0 0 189 202 1 1
SYK VWF 0 600 405 761 1 1
SYK CD63 0 0 325 338 1 2
SYK ENSG00000272980 0 0 182 240 1 1
SYK IFNAR1 0 0 419 441 1 1
SYK RABL2B 0 0 0 157 1 1
SYK IL23R 0 0 161 161 1 1
SYK NPBWR1 0 0 49 278 1 1
SYK TBC1D10C 0 0 0 173 1 1
SYK TSSK1B 0 0 0 158 1 1
SYK CD209 0 0 567 600 1 1
SYK IFI30 0 0 92 212 1 1
SYK FGD2 0 0 0 186 1 1
SYK CD300LF 0 0 123 265 1 1
SYK TRAF3IP3 0 0 0 263 1 1
SYK VCL 0 0 281 281 1 1
SYK HDC 0 0 103 198 1 1
SYK GNAI2 0 0 92 215 1 1
SYK IL7 0 0 390 390 1 1
SYK CD44 0 0 422 443 1 2
SYK HLA-DMA 0 0 132 183 1 1
SYK SEMA4D 0 0 211 290 1 1
SYK TIRAP 0 0 395 405 1 1
SYK SDK2 0 0 0 190 1 1
SYK TANK 0 0 195 208 1 2
SYK TSSK2 0 0 0 158 1 1
SYK PECAM1 0 0 323 366 1 1
SYK UBB 213 0 0 279 1 1
SYK MARCH1 0 0 96 192 1 1
SYK PTK2B 270 900 703 946 1 1
SYK INADL 0 0 0 211 1 1
SYK CCNE1 0 0 95 153 1 1
SYK TXN 0 0 142 181 1 1
SYK LCP1 0 0 90 327 1 1
SYK PHLPP2 0 0 60 178 1 1
SYK MAP2K2 0 0 154 223 1 1
SYK CD38 0 0 404 447 1 2
SYK RHEB 0 0 90 183 1 2
SYK EVL 0 0 0 184 1 1
SYK ADD1 0 0 0 210 1 1
SYK FCAR 0 0 501 513 1 1
SYK PLCE1 0 0 270 329 1 1
SYK UAP1 0 0 0 162 1 1
SYK P2RY6 0 0 95 166 1 1
SYK WIPF1 0 900 397 941 1 1
SYK EFNA1 0 0 0 168 1 1
SYK APOBR 0 0 0 183 1 1
SYK LDLR 0 0 164 221 1 2
SYK SH2D2A 280 0 107 369 1 1
SYK TUBA1A 270 0 0 298 1 1
SYK PLAGL2 0 0 0 385 1 1
SYK NOS3 0 0 161 198 1 2
SYK PPIP5K2 0 0 0 344 1 1
SYK PPM1K 0 0 0 198 1 1
SYK CD36 0 0 323 369 1 2
SYK TIMD4 0 0 125 150 1 1
SYK PRKAA1 0 0 0 158 1 2
SYK SARDH 0 0 0 190 1 1
SYK LRGUK 0 0 0 161 1 1
SYK ARHGEF7 0 0 443 486 1 1
SYK FRAT1 0 0 77 197 1 1
SYK CCND1 0 0 319 319 1 2
SYK PTPRE 0 0 64 220 1 1
SYK ICAM2 0 0 193 227 1 1
SYK CD19 270 900 785 984 1 1
SYK SIGLEC10 0 0 90 199 1 1
SYK MEGF10 270 0 92 356 1 1
SYK PTAFR 0 0 74 202 1 1
SYK ACTN1 0 0 81 159 1 1
SYK FAU 0 0 0 162 1 2
SYK BLNK 865 900 983 999 1 1
SYK IRAK2 0 0 181 294 1 1
SYK NCF1 0 0 483 553 1 1
SYK SPNS3 0 0 0 181 1 1
SYK PIK3C2B 0 0 86 169 1 1
SYK FAM46A 170 0 0 189 1 1
SYK CD207 0 0 209 223 1 1
SYK EIF4E 0 0 173 245 1 2
SYK PPP2CA 0 0 108 210 1 1
SYK PRKDC 0 0 67 152 1 2
SYK ETV6 0 0 251 333 1 1
SYK BAD 0 0 112 230 1 2
SYK YWHAQ 0 0 90 207 1 1
SYK RAB33A 0 0 43 162 1 1
SYK KAT2B 0 0 90 171 1 1
SYK GATA1 0 0 141 249 1 1
SYK TBC1D2 0 0 0 218 1 1
SYK PDE4A 0 0 157 164 1 1
SYK FCAMR 0 0 92 233 1 1
SYK CSN2 0 0 88 161 1 1
SYK MAF 0 0 135 153 1 1
SYK CLEC1A 0 0 252 265 1 1
SYK MAP1B 0 0 88 166 1 2
SYK KLHL6 0 0 61 151 1 1
SYK SRGN 0 0 75 155 1 1
SYK CRYGC 0 0 181 181 1 1
SYK PPP1CB 0 0 45 183 1 1
SYK ROCK2 0 0 193 199 1 1
SYK SIGLEC9 0 0 96 215 1 1
SYK PIK3AP1 462 800 241 936 1 1
SYK TRADD 0 0 184 196 1 1
SYK AGER 0 0 150 185 1 2
SYK LAX1 213 0 261 424 1 1
SYK SGK494 0 0 0 195 1 1
SYK PDGFRA 0 0 193 177 1 1
SYK VPS35 0 0 44 173 1 2
SYK CDH1 0 0 284 295 1 2
SYK NCF4 0 0 246 415 1 1
SYK SH3PXD2A 0 0 73 158 1 1
SYK DUSP10 0 0 82 155 1 1
SYK CD33 0 0 323 376 1 1
SYK MB21D1 0 0 171 171 1 1
SYK LEF1 0 0 131 182 1 1
SYK NUMB 0 0 0 178 1 1
SYK PDGFRB 0 0 330 227 1 2
SYK EP300 0 0 194 265 1 2
SYK SIRPA 0 800 340 867 1 1
SYK CHD1 0 0 0 390 1 1
SYK IL4 0 0 565 582 1 1
SYK NMRK1 0 0 0 164 1 1
SYK ELMO1 0 600 141 655 1 1
SYK RAP1B 0 600 218 713 1 1
SYK SEC23B 270 0 0 330 1 2
SYK SCIMP 0 0 158 206 1 1
SYK SMAD3 0 0 139 215 1 2
SYK KLK10 0 0 183 195 1 1
SYK IL17F 0 0 257 256 1 1
SYK ANXA8 0 0 161 161 1 1
SYK BIRC3 0 0 204 308 1 1
SYK DOK1 0 0 321 441 1 1
SYK ROCK1 0 0 218 254 1 2
SYK CARD17 0 0 0 187 1 1
SYK IL16 0 0 141 266 1 1
SYK CCL2 0 0 425 486 1 2
SYK ALB 0 0 457 513 1 2
SYK CD68 0 0 282 369 1 2
SYK STK10 0 0 134 157 1 1
SYK RAP2A 0 0 57 154 1 1
SYK CASP7 0 0 167 203 1 1
SYK MME 0 0 271 302 1 1
SYK TYROBP 678 800 989 999 1 1
SYK GATA4 0 0 48 152 1 2
SYK PDZD2 0 0 0 178 1 1
SYK POM121 0 0 702 702 1 1
SYK HSPA4 0 0 163 245 1 1
SYK PLAUR 0 0 140 199 1 1
SYK PIK3R1 486 900 427 973 1 1
SYK CLTC 0 0 441 441 1 1
SYK CCR2 0 0 245 344 1 2
SYK CLEC12A 0 0 500 568 1 1
SYK LILRB5 0 600 60 626 1 1
SYK HSPB3 0 0 134 157 1 1
SYK HSP90B1 0 0 107 232 1 1
SYK TEK 0 0 163 162 1 1
SYK CXCL9 0 0 324 363 1 1
SYK PPARA 0 0 142 174 1 2
SYK LIN7C 0 0 0 157 1 1
SYK TRAF6 694 0 909 973 1 2
SYK GP6 0 600 957 982 1 1
SYK PDP1 0 0 0 225 1 1
SYK RAC3 0 0 396 478 1 2
SYK PPM1L 0 0 0 198 1 1
SYK DGKZ 0 0 180 207 1 1
SYK CYCS 0 0 213 213 1 2
SYK DUSP12 0 0 113 183 1 1
SYK BMP2 0 0 52 159 1 1
SYK EGF 0 0 324 349 1 2
SYK PRTN3 0 0 203 215 1 1
SYK PTPRS 0 0 95 150 1 1
SYK PLAU 0 0 138 173 1 1
SYK GNAZ 0 0 61 188 1 1
SYK FCGRT 0 0 242 282 1 1
SYK RASAL3 0 0 0 184 1 1
SYK GAK 0 0 66 206 1 1
SYK PTK2 486 900 690 960 1 2
SYK KLRD1 0 600 455 781 1 1
SYK MAPK8 0 0 454 287 1 2
SYK TNS4 0 0 74 183 1 1
SYK ATP6V0D2 0 0 159 177 1 1
SYK MAP2K4 0 0 219 179 1 1
SYK PKDCC 0 0 0 154 1 1
SYK CLIC2 0 0 0 177 1 1
SYK C1GALT1 0 0 163 269 1 1
SYK LILRB2 0 600 136 757 1 1
SYK SLA 270 0 145 455 1 1
SYK GAB4 0 0 0 462 1 1
SYK ARHGDIB 0 0 150 256 1 1
SYK VR1 0 0 108 158 1 1
SYK STAB2 0 0 96 167 1 1
SYK DIABLO 0 0 218 233 1 2
SYK BAZ1B 0 0 0 180 1 1
SYK P2RX7 0 0 307 382 1 2
SYK CCR1 0 0 226 336 1 1
SYK PPP2CB 0 0 0 151 1 1
SYK CHKA 0 0 58 173 1 1
SYK ABI1 0 0 164 258 1 1
SYK LRIT1 0 0 0 165 1 1
SYK FYN 270 900 818 942 1 1
SYK GRB2 675 900 926 997 1 1
SYK NFKBIE 0 0 141 240 1 1
SYK EYS 0 0 0 198 1 1
SYK CLEC6A 0 600 938 976 1 1
SYK JAG1 0 0 95 150 1 1
SYK PP2D1 0 0 0 198 1 1
SYK LTA 0 0 107 300 1 1
SYK TBL1X 0 0 147 173 1 1
SYK IL7R 0 0 309 393 1 1
SYK ARAP3 0 0 122 250 1 1
SYK RABL2A 0 0 0 157 1 1
SYK NCK2 0 0 239 350 1 1
SYK EPN2 0 0 54 172 1 1
SYK TMC8 0 0 0 151 1 1
SYK LSP1 0 0 139 259 1 1
SYK FER 0 900 76 916 1 1
SYK P2RY1 0 0 214 215 1 1
SYK CLIP4 0 0 167 273 1 1
SYK IRS2 0 0 99 191 1 1
SYK SIGLEC14 0 0 321 370 1 1
SYK PPM1F 0 0 0 198 1 1
SYK KLRF2 0 0 694 700 1 1
SYK NFATC3 0 0 142 214 1 1
SYK TNFRSF13C 0 0 459 484 1 1
SYK TREM2 0 800 656 932 1 1
SYK PLCH2 0 0 0 269 1 1
SYK RUNX3 0 0 150 181 1 1
SYK TBXAS1 0 0 66 197 1 1
SYK CCNA2 0 0 129 185 1 1
SYK PRAM1 0 0 94 174 1 1
SYK PFKP 0 0 0 181 1 1
SYK HIC1 0 0 140 175 1 1
SYK AIF1 0 0 210 345 1 2
SYK ERBB4 313 0 202 393 1 1
SYK GSTA4 0 0 0 194 1 1
SYK ZNF213 0 0 0 176 1 1
SYK JAK3 0 900 558 923 1 1
SYK STXBP5 0 0 0 167 1 1
SYK PADI4 0 0 141 172 1 1
SYK ZBTB16 0 0 241 272 1 1
SYK PIK3CG 270 900 458 964 1 1
SYK GZMA 0 0 143 283 1 1
SYK DAPP1 0 0 358 477 1 1
SYK GLG1 0 0 182 205 1 1
SYK SERPINB2 0 0 50 271 1 1
SYK ITGAL 0 0 324 472 1 1
SYK TRIO 0 0 0 163 1 1
SYK PTCRA 0 0 141 234 1 1
SYK ENSG00000173366 0 0 658 712 1 1
SYK S1PR4 0 0 0 230 1 1
SYK C1orf162 0 0 0 237 1 1
SYK ETNK2 0 0 0 159 1 1
SYK ASB13 0 0 46 160 1 1
SYK PFAS 0 0 0 202 1 1
SYK JUN 0 900 519 951 1 2
SYK DAPK1 0 0 288 187 1 2
SYK CLIC5 0 0 0 159 1 1
SYK TYK2 0 0 369 176 1 1
SYK MBL2 0 0 244 257 1 1
SYK HDAC4 270 0 48 303 1 2
SYK IL21 0 0 92 249 1 1
SYK TSPAN13 0 0 95 173 1 1
SYK LTB 0 0 74 178 1 1
SYK BCL3 0 0 0 159 1 1
SYK HSP90AA1 0 0 295 393 1 2
SYK PSEN1 0 0 149 172 1 2
SYK SH2D5 0 0 75 151 1 1
SYK ATF2 0 0 125 169 1 1
SYK CRP 0 0 260 260 1 2
SYK RHOV 0 0 396 458 1 1
SYK LY6G6F 0 0 181 202 1 1
SYK CLEC2D 0 0 181 271 1 1
SYK EPRS 0 0 206 270 1 1
SYK GRAP2 270 600 725 934 1 1
SYK SELL 0 0 390 484 1 1
SYK SLA2 0 0 639 351 1 1
SYK C1S 0 0 86 165 1 1
SYK SELP 0 0 502 534 1 1
SYK GNA14 0 0 0 177 1 1
SYK MSN 270 0 892 921 1 1
SYK SLC11A2 0 0 0 161 1 1
SYK SQSTM1 0 0 137 195 1 2
SYK MICB 0 0 213 213 1 1
SYK MMP9 0 0 330 372 1 2
SYK PSD4 0 0 0 205 1 1
SYK RND1 0 0 357 423 1 1
SYK MAPK3 213 0 561 462 1 2
SYK ABCG1 0 0 76 187 1 2
SYK THY1 0 0 166 179 1 1
SYK HLA-DMB 0 0 73 198 1 1
SYK BANK1 0 0 211 295 1 1
SYK CD1C 0 0 209 291 1 1
SYK IFNAR2 0 0 160 180 1 1
SYK FGL2 0 0 45 204 1 1
SYK GSN 0 0 213 468 1 1
SYK AR 128 0 74 203 1 2
SYK CSF2RA 0 900 112 916 1 1
SYK CDKN1A 0 0 164 197 1 2
SYK SPP1 0 900 208 920 1 2
SYK GPR29 0 0 182 212 1 1
SYK TIMP1 0 0 155 169 1 1
SYK PLXNA1 0 0 143 252 1 1
SYK GNA12 0 0 0 183 1 1
SYK CRLF2 0 0 209 254 1 1
SYK AURKA 0 0 210 166 1 2
SYK PTPRC 0 0 561 679 1 1
SYK NPSR1 0 0 0 202 1 1
SYK BCR 0 900 161 916 1 2
SYK CXCR1 0 0 167 220 1 1
SYK ITGAV 0 900 218 921 1 1
SYK HUNK 0 0 0 158 1 1
SYK PMCH 0 0 265 265 1 1
SYK LILRA6 0 600 167 669 1 1
SYK BCL10 0 0 736 756 1 1
SYK IGDCC3 0 0 0 212 1 1
SYK PTPRO 270 0 324 517 1 1
SYK CRTAM 0 0 75 201 1 1
SYK ICAM1 0 0 714 721 1 2
SYK RALB 0 0 72 213 1 2
SYK ROBO1 0 0 0 153 1 1
SYK LY9 0 0 166 365 1 1
SYK RNF8 0 0 0 226 1 1
SYK PPP4C 0 0 0 177 1 1
SYK CLK3 0 0 72 155 1 1
SYK DOK2 0 0 296 446 1 1
SYK PIK3C3 0 0 128 208 1 2
SYK RPL9 0 0 0 169 1 1
SYK CXCL14 0 0 0 254 1 1
SYK GNA13 0 0 67 249 1 1
SYK STAT1 213 0 564 688 1 2
SYK SOCS5 0 0 127 223 1 1
SYK GZMB 0 0 364 435 1 1
SYK RPL32 0 0 58 162 1 1
SYK IL17D 0 0 88 180 1 1
SYK KCNMA1 0 0 646 654 1 1
SYK PLEK 0 0 519 665 1 1
SYK GCA 0 0 61 173 1 1
SYK NRP2 0 0 150 181 1 1
SYK RRAS 0 0 96 189 1 1
SYK CXCR4 0 0 423 468 1 2
SYK MMP1 0 0 154 153 1 1
SYK SH3BP2 735 0 778 944 1 1
SYK MTOR 0 0 492 538 1 2
SYK TRIB2 0 0 0 162 1 1
SYK CD163 0 0 180 262 1 1
SYK PSMC6 0 0 167 255 1 1
SYK CTNNB1 0 0 321 472 1 2
SYK HRAS 0 800 358 897 1 2
SYK APP 45 0 219 253 1 2
SYK EGR1 0 0 188 221 1 2
SYK TRPV1 0 0 108 158 1 2
SYK MTSS1 0 0 74 172 1 1
SYK DCLK3 0 0 708 371 1 1
SYK RHOBTB1 0 0 388 451 1 1
SYK PASK 0 0 0 158 1 1
SYK WNT2B 0 0 0 154 1 1
SYK ALG1 0 0 0 157 1 1
SYK C3AR1 0 0 150 233 1 1
SYK IKBKE 0 0 142 187 1 1
SYK IGSF9B 0 0 0 175 1 1
SYK NEDD4 0 800 206 840 1 2
SYK NR1H3 0 0 60 188 1 1
SYK RAB5A 0 0 181 211 1 2
SYK VAV3 0 900 706 972 1 1
SYK PLD4 0 0 0 188 1 1
SYK ENSG00000268500 0 0 173 304 1 1
SYK CXCL8 0 0 501 501 1 2
SYK NFKBID 0 0 123 252 1 1
SYK ARF3 0 0 123 229 1 1
SYK IL6R 0 0 181 221 1 1
SYK B3GAT1 0 0 295 299 1 1
SYK CD22 486 900 799 989 1 1
SYK FGFR2 0 0 155 158 1 1
SYK TRPC3 0 0 184 221 1 1
SYK GAPDH 0 0 457 478 1 2
SYK ALG1L 0 0 0 157 1 1
SYK LPAR5 0 0 0 160 1 1
SYK DUSP5 0 0 181 246 1 1
SYK CD83 0 0 234 267 1 1
SYK OAS2 0 0 113 164 1 1
SYK ABL1 0 0 506 163 1 1
SYK DYNC1I1 129 0 0 155 1 1
SYK EBF1 0 0 233 248 1 1
SYK CX3CL1 0 0 173 173 1 1
SYK TSSK3 0 0 0 157 1 1
SYK MAP2K7 0 0 528 297 1 1
SYK GSTM3 0 0 0 200 1 1
SYK CLNK 0 0 151 192 1 1
SYK TLR10 0 0 194 390 1 1
SYK ZAP70 0 900 916 907 1 1
SYK ITGA4 42 0 270 329 1 1
SYK STAT4 0 0 207 364 1 1
SYK ARHGAP4 0 0 45 170 1 1
SYK DPEP2 0 0 0 167 1 1
SYK EVPL 0 0 106 165 1 1
SYK CD7 0 0 181 230 1 1
SYK NFKB1 0 900 183 926 1 2
SYK MBOAT2 0 0 52 163 1 1
SYK RELA 0 900 335 933 1 2
SYK CDH13 0 0 167 180 1 1
SYK PRRC2B 0 0 54 251 1 1
SYK INPPL1 0 0 400 270 1 1
SYK WASL 0 0 302 374 1 1
SYK TNFSF13 0 0 104 202 1 1
SYK CTNND1 0 0 108 162 1 1
SYK RHOJ 0 0 386 449 1 1
SYK DIAPH1 0 0 53 153 1 1
SYK GRID2IP 0 0 0 260 1 1
SYK IL4R 0 0 675 696 1 1
SYK CACFD1 0 0 90 157 1 1
SYK IQGAP1 0 0 123 175 1 1
SYK C5AR1 0 0 235 288 1 1
SYK ARHGAP30 0 0 67 251 1 1
SYK BCL11B 0 0 113 281 1 1
SYK IGJ 0 360 113 438 1 1
SYK RHOBTB2 0 0 388 451 1 1
SYK CREBBP 0 0 188 260 1 1
SYK KHDRBS1 0 0 90 176 1 1
SYK APC 0 0 0 151 1 1
SYK IL2RB 213 900 174 942 1 1
SYK SH3KBP1 0 500 392 695 1 1
SYK ARL14 0 0 60 157 1 1
SYK EFNB1 0 0 73 196 1 1
SYK GSDMD 0 0 241 276 1 2
SYK CREB1 0 0 325 325 1 2
SYK LILRB1 0 600 546 830 1 1
SYK ALG11 0 0 0 157 1 1
SYK CLEC1B 0 800 955 991 1 1
SYK FRS2 0 0 67 195 1 1
SYK ATCAY 0 0 0 154 1 1
SYK FKBP11 0 0 0 153 1 1
SYK BRCA1 0 0 193 193 1 2
SYK CCL21 0 0 241 257 1 1
SYK STK11 0 0 171 209 1 2
SYK HNRNPU 213 0 418 529 1 1
SYK TCF3 0 0 321 321 1 1
SYK FUT4 0 0 150 179 1 1
SYK CDKN2D 0 0 74 208 1 1
SYK MAP3K8 0 0 195 253 1 1
SYK SOAT1 0 0 0 153 1 1
SYK FLNA 273 0 552 689 1 1
SYK TFEC 0 0 0 172 1 1
SYK CLEC4A 0 0 413 487 1 1
SYK IL17RC 0 0 173 173 1 1
SYK CASP10 0 0 74 162 1 1
SYK DUSP4 0 0 73 153 1 1
SYK LY75 0 0 293 376 1 1
SYK TCL1B 0 0 373 373 1 1
SYK LAG3 0 0 193 210 1 1
SYK MEFV 0 0 327 376 1 1
SYK PIM1 0 0 74 191 1 1
SYK RICTOR 0 0 160 238 1 2
SYK SOAT2 0 0 0 153 1 1
SYK ARHGEF28 0 0 97 157 1 1
SYK DVL1 0 0 0 164 1 1
SYK GNAQ 0 0 205 318 1 1
SYK WDR64 0 0 0 158 1 1
SYK PIK3R3 0 800 164 839 1 1
SYK CEACAM5 0 0 138 161 1 1
SYK GAB2 213 900 535 960 1 1
SYK IL2RA 0 900 685 968 1 1
SYK ACP5 0 0 325 417 1 1
SYK PLCL1 0 0 0 177 1 1
SYK PPP5C 0 0 0 150 1 1
SYK DGAT1 0 0 56 320 1 2
SYK CBLB 678 900 101 981 1 1
SYK TLN1 0 600 260 698 1 1
SYK UCK2 0 0 0 194 1 1
SYK KISS1R 0 0 57 171 1 1
SYK IL15 0 0 392 406 1 1
SYK ITGAE 0 0 216 250 1 1
SYK RALGDS 0 0 134 167 1 1
SYK LGMN 0 0 60 158 1 1
SYK NR0B2 0 0 549 566 1 1
SYK IFNA1 0 0 455 455 1 1
SYK ILK 0 0 234 198 1 1
SYK WNT5A 0 0 143 233 1 2
SYK ROBO4 0 0 0 153 1 1
SYK ABI3 0 0 128 299 1 1
SYK ADRBK2 0 0 0 159 1 1
SYK TAGAP 0 0 0 246 1 1
SYK CSH2 0 0 667 667 1 1
SYK RGS10 0 0 82 170 1 1
SYK ADAM10 0 0 163 163 1 1
SYK MICA 0 0 240 239 1 1
SYK ITGA5 0 0 113 182 1 1
SYK FCRL2 0 0 150 191 1 1
SYK PTPN22 0 0 377 507 1 1
SYK SEMA3B 0 0 122 162 1 1
SYK ETNK1 0 0 0 159 1 1
SYK RASGRP3 0 0 249 315 1 1
SYK ITGB8 0 0 66 501 1 1
SYK CD300C 0 0 122 258 1 1
SYK VAMP8 0 0 155 282 1 2
SYK TP53RK 0 0 0 196 1 1
SYK JAK2 0 0 517 219 1 2
SYK NLRC5 0 0 84 157 1 1
SYK C19orf24 0 0 0 168 1 1
SYK BRD7 270 0 0 281 1 1
SYK PTPN4 0 0 68 166 1 1
SYK PTX3 0 0 157 167 1 1
SYK CDH2 0 0 139 153 1 1
SYK HDAC6 270 0 108 347 1 2
SYK APAF1 0 0 167 228 1 2
SYK GNAT1 0 0 0 171 1 1
SYK SHC3 0 800 72 826 1 1
SYK MELK 0 0 118 188 1 1
SYK BRD4 0 0 112 191 1 2
SYK CALM3 0 0 122 195 1 1
SYK NR4A1 0 0 232 261 1 2
SYK ATP2B4 0 0 97 154 1 1
SYK IRAK1 0 0 467 324 1 1
SYK PSTPIP2 0 0 143 198 1 1
SYK RAF1 0 0 310 155 1 2
SYK CARD9 0 800 988 997 1 1
SYK DOK3 0 0 395 517 1 1
SYK MAP3K7 270 0 208 402 1 2
SYK HDAC2 270 0 74 322 1 1
SYK TNS3 0 0 54 157 1 1
SYK TRIM15 191 0 0 204 1 1
SYK APBB1IP 0 600 244 732 1 1
SYK TNFRSF11B 0 0 150 174 1 1
SYK CD200R1 0 0 181 238 1 1
SYK NFKBIZ 0 0 141 231 1 1
SYK MDM2 0 0 317 328 1 2
SYK TP53 116 0 460 521 1 2
SYK SOX18 0 0 175 242 1 1
SYK PTPRCAP 0 0 103 238 1 1
SYK STEAP4 0 0 0 160 1 1
SYK NR1H2 0 0 0 245 1 1
SYK FLNB 0 0 57 175 1 1
SYK RASGRP1 0 0 459 507 1 1
SYK FGFR3 0 0 209 175 1 1
SYK LAMP1 0 0 325 349 1 2
SYK TSLP 0 0 294 294 1 1
SYK NCKAP1 0 0 66 160 1 1
SYK SLC2A1 0 0 124 189 1 2
SYK EGFR 359 0 689 526 1 2
SYK CFLAR 0 0 193 241 1 2
SYK KANK1 0 0 0 150 1 1
SYK PPP1CC 0 0 82 224 1 1
SYK TNFRSF4 0 0 195 238 1 1
SYK IL10 0 0 563 590 1 2
SYK MS4A2 270 900 323 948 1 1
SYK PPP3R1 0 0 106 161 1 1
SYK ARVCF 0 0 0 154 1 1
SYK UBASH3A 0 0 375 424 1 1
SYK IRAK4 0 0 418 320 1 1
SYK NPM1 0 0 213 235 1 1
SYK FLT3 376 600 668 833 1 2
SYK SKAP2 0 0 320 345 1 1
SYK TRAIP 270 0 170 378 1 1
SYK DLG4 0 0 107 173 1 2
SYK PREX1 0 0 161 215 1 1
SYK GDF15 0 0 46 154 1 1
SYK HLA-A 0 0 190 202 1 1
SYK MDM4 0 0 167 223 1 1
SYK CCL3 0 0 450 498 1 1
SYK CTSG 0 0 162 224 1 1
SYK CCL22 0 0 187 204 1 1
SYK DIRC3 0 0 0 202 1 1
SYK FCGR3B 0 900 583 960 1 1
SYK MARCO 0 0 181 244 1 1
SYK ATP7B 0 0 0 152 1 1
SYK BRMS1 0 0 113 192 1 1
SYK TSPAN6 0 0 0 179 1 1
SYK IL18RAP 0 0 137 226 1 1
SYK RORC 0 0 171 180 1 1
SYK CLEC4E 0 800 898 982 1 1
SYK IL21R 0 0 161 289 1 1
SYK TNFRSF9 0 0 204 204 1 1
SYK DOCK8 0 0 265 422 1 1
SYK FCGR2A 865 800 943 998 1 1
SYK FKBP2 0 0 49 589 1 1
SYK TSSK6 0 0 0 157 1 1
SYK CORO1B 0 0 84 194 1 1
SYK E2F3 0 0 113 152 1 1
SYK CD79A 270 900 988 999 1 1
SYK CHFR 0 0 90 167 1 1
SYK RARB 0 0 180 210 1 1
SYK CHD2 0 0 0 178 1 1
SYK FERMT3 0 0 391 498 1 1
SYK KIT 128 0 491 345 1 2
SYK SKAP1 0 360 357 607 1 1
SYK FGB 0 600 0 606 1 1
SYK CEACAM3 0 0 331 371 1 1
SYK CYTIP 0 0 0 342 1 1
SYK PDCD1LG2 0 0 233 249 1 1
SYK CD200 0 0 157 156 1 1
SYK IGHV3-11 0 500 0 531 1 1
SYK NME8 0 0 0 225 1 1
SYK NFATC1 0 0 503 574 1 2
SYK TERF1 295 0 0 295 1 1
SYK BST2 0 0 235 287 1 1
SYK STK40 0 0 0 158 1 1
SYK TNFRSF11A 0 0 398 408 1 1
SYK NLRP6 0 0 193 238 1 1
SYK FPR1 0 0 184 282 1 1
SYK SLC9C2 0 0 0 221 1 1
SYK MCEMP1 0 0 0 151 1 1
SYK MCF2 0 0 193 243 1 1
SYK CXCR3 0 0 234 304 1 1
SYK MIB1 0 0 0 188 1 1
SYK TNFAIP2 0 0 0 162 1 1
SYK IRF1 0 0 280 332 1 2
SYK ATP4A 0 0 124 178 1 1
SYK PLCD3 0 0 61 253 1 1
SYK PLCD1 0 0 0 210 1 1
SYK C1QA 0 0 74 204 1 1
SYK PTPRA 0 0 95 180 1 1
SYK BMP8A 0 0 66 172 1 1
SYK PRKD1 270 0 845 541 1 1
SYK ENSG00000279765 0 0 0 178 1 1
SYK ILKAP 0 0 0 198 1 1
SYK ANKRD22 0 0 45 166 1 1
SYK TRIP6 0 0 70 159 1 1
SYK POU2AF1 161 0 458 693 1 1
SYK PDK4 0 0 0 197 1 1
SYK PDCD1 0 0 248 276 1 2
SYK PIM2 0 0 243 232 1 1
SYK ESR1 0 0 256 283 1 2
SYK IFNB1 0 0 458 457 1 1
SYK CHKB 0 0 67 181 1 1
SYK NCL 0 0 103 297 1 2
SYK UBE2D2 0 0 172 199 1 1
SYK PLEKHA2 0 0 123 185 1 1
SYK CPNE8 290 0 0 301 1 1
SYK EOMES 0 0 125 171 1 1
SYK RNF146 0 0 103 162 1 1
SYK ST8SIA2 0 0 181 181 1 1
SYK AIRE 0 0 166 228 1 1
SYK CCR9 0 0 107 161 1 1
SYK RAG2 0 0 332 332 1 1
SYK KLRC2 0 600 501 793 1 1
SYK FN1 0 600 452 771 1 2
SYK FCRL1 0 0 81 170 1 1
SYK SPRED2 0 0 0 184 1 2
SYK CSNK2B 0 0 0 166 1 1
SYK C3 0 0 296 311 1 2
SYK GEM 0 0 0 193 1 1
SYK MMP13 0 0 135 168 1 2
SYK DST 0 0 69 162 1 2
SYK PRKCA 213 0 390 351 1 1
SYK ELANE 0 0 184 216 1 1
SYK CD300LB 0 0 232 347 1 1
SYK PKN3 0 0 108 165 1 1
SYK MAP4 0 0 69 168 1 1
SYK RIN3 0 0 52 172 1 1
SYK PIGA 0 0 0 230 1 1
SYK UBC 0 0 73 150 1 2
SYK SERPINB5 0 0 154 284 1 1
SYK XCL1 0 0 108 237 1 1
SYK SPHK1 0 900 157 913 1 2
SYK SLC15A3 0 0 0 206 1 1
SYK EFNA2 0 0 0 168 1 1
SYK PAG1 270 0 391 566 1 1
SYK TERT 0 0 136 181 1 2
SYK TET2 0 0 202 219 1 2
SYK OBBP2 0 0 173 203 1 1
SYK KCNN4 0 0 112 179 1 1
SYK TIFAB 0 0 0 155 1 1
SYK VAV1 969 900 988 999 1 1
SYK NCF2 0 0 211 405 1 1
SYK FASLG 0 900 233 920 1 1
SYK SOCS3 0 0 287 347 1 1
SYK MNDA 0 0 45 217 1 1
SYK IGSF6 0 0 0 359 1 1
SYK RHOD 0 0 367 432 1 1
SYK PTPN18 0 0 75 245 1 1
SYK STAT5A 213 900 505 963 1 1
SYK ARRDC5 0 0 0 199 1 1
SYK FOXN1 0 0 71 159 1 1
SYK RNASE6 0 0 0 229 1 1
SYK KIAA1614 0 0 0 189 1 1
SYK HAX1 0 0 170 192 1 1
SYK PKN2 0 0 73 150 1 1
SYK LILRB4 0 600 120 662 1 1
SYK ITGB2 486 0 454 804 1 1
SYK KRAS 0 800 260 885 1 2
SYK TSSK4 0 0 0 158 1 1
SYK CD3E 945 900 149 997 1 1
SYK RND2 0 0 355 421 1 1
SYK HLA-B 0 0 166 209 1 1
SYK BECN1 0 0 140 169 1 2
SYK MAPT 270 0 154 424 1 2
SYK HLA-DPA1 0 0 46 160 1 1
SYK EEF1G 0 0 53 215 1 1
SYK MYO16 0 0 49 152 1 1
SYK THBS1 0 0 202 220 1 1
SYK FBXL19 0 0 0 175 1 1
SYK SHC4 0 800 73 832 1 1
SYK TLR6 0 0 391 497 1 1
SYK GYS1 0 0 49 164 1 1
SYK IL2 0 900 560 954 1 1
SYK ANXA1 0 0 190 208 1 1
SYK ITGA2 0 0 630 643 1 1
SYK VSIG4 0 0 81 174 1 1
SYK OLR1 0 0 234 247 1 2
SYK GIT2 0 0 97 157 1 1
SYK LRP1 129 0 112 217 1 1
SYK FLT4 0 0 265 205 1 1
SYK MAPK11 0 900 134 919 1 1
SYK DUSP1 0 0 267 325 1 1
SYK IPO7 0 0 615 615 1 1
SYK DNAJC10 0 0 0 166 1 1
SYK CDKN2C 0 0 91 185 1 1
SYK HSH2D 0 0 105 189 1 1
SYK PPM1A 0 0 0 198 1 1
SYK IL18R1 0 0 96 168 1 1
SYK ENSG00000251246 0 0 0 168 1 1
SYK SGK223 0 0 157 156 1 1
SYK CDC25A 0 0 126 174 1 1
SYK BIN2 0 0 43 241 1 1
SYK CD81 0 0 320 371 1 1
SYK COL9A1 0 0 0 151 1 1
SYK CD72 270 900 451 961 1 1
SYK MADCAM1 0 0 156 175 1 1
SYK CARD11 0 0 558 605 1 1
SYK HLA-DRA 0 0 74 189 1 1
SYK PLD2 0 0 209 227 1 1
SYK CARD16 0 0 0 216 1 1
SYK HDAC9 270 0 43 299 1 1
SYK CD53 0 0 164 329 1 1
SYK KIR2DL1 0 0 246 277 1 1
SYK NLRP3 270 0 745 843 1 2
SYK REL 0 0 392 470 1 2
SYK MSR1 0 0 148 175 1 1
SYK ERBB3 313 0 216 401 1 1
SYK CASP3 0 0 342 357 1 2
SYK RASGRP4 0 0 171 277 1 1
SYK WASF2 0 0 308 344 1 1
SYK F3 0 0 193 193 1 1
SYK PTGS2 0 0 341 379 1 2
SYK NKG7 0 0 0 163 1 1
SYK ABCA7 0 0 74 151 1 1
SYK TNNI2 0 0 45 206 1 1
SYK TNFSF13B 0 0 518 567 1 1
SYK CTSS 0 0 74 273 1 1
SYK PPM1B 0 0 0 198 1 1
SYK VPS13A 0 0 124 224 1 1
SYK RNASE2 0 0 54 161 1 1
SYK IL13 0 0 457 461 1 2
SYK RASGRF1 0 0 208 277 1 1
SYK TONSL 0 0 92 166 1 1
SYK CYBB 0 0 370 534 1 2
SYK MAL 270 0 0 282 1 1
SYK VEGFC 0 0 244 270 1 1
SYK FPR3 0 0 82 159 1 1
SYK GPR65 0 0 0 187 1 1
SYK LIME1 0 360 72 380 1 1
SYK MAPK15 0 0 88 173 1 1
SYK PTS 0 0 395 394 1 1
SYK TREML2 0 0 171 250 1 1
SYK ARRB2 0 0 90 192 1 1
SYK CDKN2A 0 0 338 392 1 2
SYK FGD3 0 0 0 243 1 1
SYK PPP6C 0 0 112 235 1 1
SYK GSK3B 0 0 167 151 1 2
SYK MRC1 0 0 322 368 1 1
SYK TUBG1 270 0 0 292 1 1
SYK IL1RAP 0 0 150 163 1 1
SYK PLCZ1 0 0 66 151 1 1
SYK ITPKB 0 0 214 284 1 1
SYK DUSP2 0 0 69 162 1 1
SYK GP5 0 0 62 160 1 1
SYK NRROS 0 0 0 181 1 1
SYK PIGR 0 0 112 201 1 1
SYK CIITA 0 0 205 320 1 1
SYK NOD2 0 0 394 466 1 2
SYK ADAM28 0 0 113 189 1 1
SYK KIDINS220 0 0 453 498 1 1
SYK PIK3CD 0 800 497 908 1 1
SYK CEBPB 0 0 218 265 1 2
SYK SLC4A1 463 0 0 586 1 1
SYK ARRDC3 0 0 0 392 1 1
SYK LTBR 0 0 134 170 1 1
SYK WDR91 0 0 67 163 1 1
SYK SCRIB 0 0 66 165 1 1
SYK STAT6 0 0 392 484 1 1
SYK EIF2AK3 0 0 322 173 1 2
SYK ENAH 0 0 0 184 1 1
SYK TREML1 0 0 325 365 1 1
SYK COASY 270 0 0 285 1 1
SYK TCL1A 0 0 369 399 1 1
SYK CADM1 0 0 171 228 1 1
SYK FLT1 0 0 213 183 1 1
SYK ROBO2 0 0 0 153 1 1
SYK RABGEF1 0 0 55 170 1 1
SYK PLSCR1 0 0 155 180 1 1
SYK HRH1 0 0 140 291 1 1
SYK FRMPD2 0 0 0 244 1 1
SYK LGALS3 0 0 493 520 1 2
SYK GRAP 0 0 320 507 1 1
SYK DOCK2 0 0 284 421 1 1
SYK HSPA12A 0 0 0 179 1 1
SYK SRC 675 900 988 975 1 2
SYK RASGEF1B 0 0 0 161 1 1
SYK RAET1E 0 0 306 306 1 1
SYK RAB25 0 0 0 157 1 2
SYK YWHAB 0 0 94 211 1 1
SYK SPRED1 0 0 74 212 1 1
SYK CD47 0 0 324 323 1 2
SYK EEA1 0 0 210 229 1 2
SYK STAP1 0 0 140 277 1 1
SYK CTCF 0 0 75 159 1 1
SYK CD2 0 900 367 942 1 1
SYK CDKN1B 0 0 171 186 1 2
SYK TGOLN2 0 0 444 453 1 1
SYK HACE1 0 0 0 169 1 1
SYK ARHGAP15 0 0 0 172 1 1
SYK PPM1D 0 0 0 198 1 1
SYK TSC2 0 0 149 176 1 2
SYK C1QB 0 0 90 187 1 1
SYK F2R 0 0 448 448 1 1
SYK PF4 0 0 325 368 1 1
SYK PTPRQ 0 0 0 181 1 1
SYK ICOS 0 0 119 244 1 1
SYK ANPEP 0 0 134 164 1 1
SYK RASSF1 0 0 256 256 1 1
SYK MITF 0 0 156 170 1 2
SYK JAK1 213 900 544 933 1 2
SYK PTPN7 0 0 57 193 1 1
SYK NFATC2 0 0 296 328 1 1
SYK LILRA5 0 600 105 647 1 1
SYK P2RX1 0 0 112 260 1 1
SYK WASF1 0 0 135 150 1 1
SYK NCR2 0 0 375 388 1 1
SYK TICAM2 0 0 67 195 1 1
SYK LRRK1 0 0 91 155 1 1
SYK CD82 0 0 155 176 1 1
SYK LIN28B 0 0 63 191 1 1
SYK RHOH 0 0 475 551 1 1
SYK EPB41 0 0 261 274 1 1
SYK HMOX1 0 0 160 173 1 2
SYK IL32 0 0 170 169 1 1
SYK PDK3 0 0 0 197 1 1
SYK XIAP 0 0 241 300 1 2
SYK PPP2R4 0 0 246 282 1 1
SYK GMFG 0 0 0 173 1 1
SYK SERPINB6 0 0 0 160 1 1
SYK DLG1 0 0 81 168 1 1
SYK RUNX2 0 0 150 173 1 2
SYK SEMA6D 0 0 167 186 1 1
SYK CLEC4C 0 0 632 638 1 1
SYK IKBKB 0 0 395 231 1 2
SYK ALOX5AP 0 0 0 173 1 1
SYK SWAP70 0 0 240 308 1 1
SYK PANX1 0 0 154 153 1 1
SYK FGFR1 0 0 254 190 1 1
SYK CD4 270 900 605 975 1 2
SYK FEZ2 0 0 44 167 1 1
SYK ARL15 0 0 0 193 1 1
SYK GNAL 0 0 0 211 1 1
SYK UCKL1 0 0 0 194 1 1
SYK CARD14 0 0 127 200 1 1
SYK IL12RB1 0 0 209 269 1 1
SYK LY96 0 0 373 386 1 1
SYK CD48 0 0 230 342 1 1
SYK AKT1 0 0 702 348 1 2
SYK CYTH4 0 0 0 274 1 1
SYK TGFB2 0 0 74 230 1 1
SYK PPARG 0 0 662 694 1 2
SYK NLRP7 0 0 175 190 1 1
SYK CTSC 0 0 92 153 1 1
SYK GYS2 0 0 0 157 1 1
SYK ERBB2 407 0 337 501 1 2
SYK ANXA10 0 0 74 433 1 1
SYK CR2 0 0 469 502 1 1
SYK ESAM 0 0 133 156 1 1
SYK IRF3 0 0 406 415 1 2
SYK TLR9 270 0 701 813 1 2
SYK GZMK 0 0 81 220 1 1
SYK CLEC12B 0 0 276 332 1 1
SYK CFP 0 0 61 188 1 1
SYK CD1D 0 0 210 256 1 1
SYK KIR2DL4 0 0 242 291 1 1
SYK PYCARD 270 0 507 700 1 2
SYK MAP3K1 0 0 181 159 1 1
SYK RHOC 0 0 357 423 1 1
SYK PIKFYVE 0 0 139 165 1 2
SYK MALT1 0 0 619 635 1 1
SYK FGG 0 600 42 606 1 1
SYK CXCL10 0 0 322 356 1 2
SYK RPL7L1 0 0 0 202 1 1
SYK ITGB6 0 0 160 206 1 1
SYK BIRC5 0 0 122 190 1 2
SYK SIGLEC6 0 0 113 165 1 1
SYK CCNG2 0 0 0 200 1 1
SYK SIAE 0 0 118 167 1 1
SYK ARHGAP9 0 0 0 208 1 1
SYK FHIT 0 0 166 165 1 1
SYK IRF7 0 0 340 389 1 1
SYK ITIH4 0 0 182 200 1 1
SYK SOCS4 0 0 116 243 1 1
SYK PARD6A 0 0 0 189 1 1
SYK UBASH3B 486 0 711 851 1 1
SYK MS4A14 0 0 0 152 1 1
SYK NAPEPLD 0 0 0 186 1 1
SYK IFI16 0 0 163 163 1 1
SYK CSNK2A1 0 0 109 205 1 1
SYK TXNIP 0 0 149 244 1 2
SYK PROX1 0 0 172 192 1 1
SYK CD9 0 0 259 313 1 1
SYK RAB7A 0 0 151 238 1 2
SYK S100A9 0 0 49 170 1 1
SYK GSTP1 0 0 181 193 1 1
SYK NFKB2 0 0 282 356 1 1
SYK RND3 0 0 359 425 1 1
SYK IL34 0 0 144 185 1 1
SYK ATP12A 0 0 126 180 1 1
SYK SPN 0 0 454 515 1 1
SYK TNFAIP3 0 0 234 296 1 2
SYK IL5 0 0 401 405 1 1
SYK RPS6KA2 270 0 169 369 1 1
SYK MAP4K1 213 0 193 332 1 1
SYK IL1R2 0 0 123 180 1 1
SYK CD70 0 0 173 173 1 1
SYK TFRC 0 0 220 292 1 1
SYK RHOF 0 0 396 458 1 1
SYK CCND2 0 0 294 294 1 1
SYK PLAG1 0 0 67 666 1 1
SYK FUT7 0 0 84 177 1 1
SYK ITCH 0 0 124 157 1 1
SYK MAP4K2 0 0 155 166 1 1
SYK SIRPG 0 800 83 821 1 1
SYK NFAT5 0 0 67 437 1 1
SYK CLEC10A 0 0 107 223 1 1
SYK DIAPH3 0 0 66 165 1 1
SYK MS4A6A 0 0 65 247 1 1
SYK NAIP 0 0 161 249 1 1
SYK DDX17 0 0 401 412 1 1
SYK TRAP1 0 0 0 174 1 2
SYK FAIM3 0 0 95 175 1 1
SYK VDR 0 0 74 150 1 2
SYK PIK3R2 192 800 457 912 1 1
SYK IL1RN 0 0 292 353 1 1
SYK MMP3 0 0 212 212 1 1
SYK ITK 0 900 763 938 1 1
SYK ITGA9 0 0 131 214 1 1
SYK AQP5 0 0 0 308 1 1
SYK TNF 0 0 638 684 1 2
SYK IFITM1 0 0 154 153 1 1
SYK PLCB1 0 0 94 159 1 1
SYK LAT 463 900 802 988 1 1
SYK KIR3DL1 0 0 284 313 1 1
SYK DUSP6 0 0 113 200 1 1
SYK PDPK1 0 0 167 211 1 2
SYK IGHV3-43D 0 360 0 360 1 1
SYK PLCH1 0 0 0 265 1 1
SYK CAT 0 0 204 240 1 2
SYK GFI1 0 0 61 152 1 1
SYK DEK 0 0 95 150 1 1
SYK ARHGAP25 0 0 0 204 1 1
SYK ELMO2 0 600 0 606 1 1
SYK TRAF3IP2 270 0 60 296 1 1
SYK HGF 0 0 139 152 1 2
SYK KIF14 0 0 103 221 1 1
SYK NUMBL 0 0 0 178 1 1
SYK HRK 0 0 153 211 1 1
SYK RASA1 213 0 128 262 1 1
SYK SLC9A3R1 0 0 893 905 1 1
SYK CANX 129 0 185 278 1 2
SYK OCSTAMP 0 0 150 168 1 1
SYK DOCK5 0 0 99 205 1 1
SYK PTPN2 0 0 204 253 1 2
SYK MYB 0 0 113 156 1 1
SYK ITSN1 0 0 74 257 1 1
SYK RNASEL 0 0 66 165 1 1
SYK HPRT1 0 0 167 171 1 1
SYK CTLA4 0 0 518 536 1 2
SYK PACS1 0 0 142 295 1 1
SYK ARHGAP5 0 0 0 174 1 1
SYK RRAS2 0 0 202 297 1 1
SYK CD97 0 0 109 161 1 1
SYK CCL19 0 0 223 302 1 1
SYK HLA-E 0 600 302 724 1 1
SYK HEXB 0 0 0 303 1 1
SYK CLIC3 0 0 0 151 1 1
SYK ARL16 0 0 0 157 1 1
SYK FLT3LG 0 600 212 671 1 1
SYK ARAP1 0 0 89 151 1 1
SYK RAB44 0 0 0 173 1 1
SYK VSTM1 0 0 137 152 1 1
SYK CD274 0 0 317 331 1 2
SYK CSF2RB 213 900 107 943 1 1
SYK HK3 0 0 0 198 1 1
SYK PRPF19 0 0 0 181 1 1
SYK DVL2 0 0 0 164 1 2
SYK ATR 0 0 87 201 1 2
SYK STIM1 0 0 378 378 1 2
SYK C6orf25 0 900 377 935 1 1
SYK FOXC2 0 0 134 215 1 1
SYK ABCG2 0 0 128 381 1 1
SYK PDLIM7 0 0 177 213 1 1
SYK CD302 0 0 96 170 1 1
SYK IRS1 0 0 181 264 1 2
SYK SGK1 0 0 156 157 1 2
SYK CBL 941 900 988 999 1 1
SYK SNX20 0 0 0 204 1 1
SYK LOX 0 0 167 180 1 2
SYK EGR2 0 0 181 214 1 1
SYK GNLY 0 0 97 150 1 1
SYK EPOR 270 0 163 374 1 1
SYK KLRG1 0 900 161 914 1 1
SYK P2RY10 0 0 0 157 1 1
SYK PGR 0 0 144 176 1 1
SYK CDK1 0 0 212 157 1 2
SYK LEPREL2 0 0 201 201 1 1
SYK LRRC25 0 0 0 172 1 1
SYK TNFAIP8 0 0 125 213 1 1
SYK TTBK1 0 0 141 282 1 1
SYK RPS6KB1 270 0 279 394 1 2
SYK REM1 0 0 0 387 1 1
SYK FCGR1A 600 800 797 984 1 1
SYK PIK3R5 0 900 213 930 1 1
SYK DPP4 0 0 276 293 1 1
SYK LLGL1 0 0 0 177 1 1
SYK PLCD4 0 0 0 233 1 1
SYK CCL4 0 0 371 448 1 1
SYK RHOB 0 650 328 780 1 1
SYK IL1A 0 0 334 334 1 1
SYK CEACAM1 0 0 287 318 1 1
SYK MAVS 0 0 233 261 1 2
SYK DNM2 0 0 164 211 1 1
SYK CUL5 0 0 83 163 1 1
SYK FECH 0 0 49 154 1 1
SYK YWHAG 0 0 399 476 1 1
SYK GLI2 0 0 57 342 1 2
SYK AIM2 0 0 390 418 1 2
SYK DDX58 0 0 391 413 1 1
SYK C4B 0 0 125 214 1 1
SYK PLG 0 0 150 173 1 1
SYK SPPL2A 0 0 134 188 1 1
SYK AMICA1 0 0 55 193 1 1
SYK TRIM21 0 0 194 224 1 1
SYK FRK 0 0 695 199 1 1
SYK SNX15 0 0 0 163 1 1
SYK RAP2B 0 0 123 213 1 1
SYK PDPN 0 600 460 776 1 1
SYK DDX55 0 0 0 169 1 1
SYK PTPRJ 0 0 427 481 1 1
SYK BMP7 0 0 45 153 1 1
SYK RGS13 0 0 143 309 1 1
SYK CLEC2B 0 0 235 297 1 1
SYK NPBWR2 0 0 0 272 1 1
SYK XKR4 0 0 0 537 1 1
SYK CSNK2A2 0 0 142 475 1 1
SYK ENSG00000272822 0 0 0 157 1 1
SYK IL9 0 0 234 234 1 1
SYK ROBO3 0 0 0 153 1 1
SYK MYLK 0 0 195 152 1 1
SYK ARL17A 0 0 0 157 1 1
SYK MLLT4 0 0 138 190 1 1
SYK SERPINB1 0 0 0 234 1 1
SYK PIP5K1C 0 0 150 250 1 1
SYK PPEF1 0 0 0 205 1 1
SYK PLCL2 0 0 0 269 1 1
SYK SIT1 270 0 88 344 1 1
SYK HVCN1 0 0 171 261 1 1
SYK IGLL5 0 500 323 678 1 1
SYK MAGT1 0 0 74 262 1 1
SYK ALG1L2 0 0 0 157 1 1
SYK CD276 0 0 370 370 1 1
SYK PPM1G 0 0 0 218 1 1
SYK KIF16B 0 0 0 153 1 1
SYK CASP8 0 0 358 414 1 2
SYK ITGB1 0 0 419 537 1 1
SYK AOAH 0 0 0 165 1 1
SYK DHDH 0 0 140 154 1 1
SYK HSPG2 0 0 0 158 1 1
SYK TNFAIP8L2 0 0 0 203 1 1
SYK XCR1 0 0 120 258 1 1
SYK RDX 0 0 384 418 1 1
SYK CX3CR1 0 0 257 300 1 1
SYK CLEC17A 0 0 456 486 1 1
SYK BPTF 0 0 0 260 1 1
SYK DAB2 0 0 170 296 1 1
SYK DLG5 0 0 0 182 1 1
SYK RPTOR 0 0 174 236 1 2
SYK ITGA1 0 0 123 154 1 1
SYK LRMP 0 0 74 187 1 1
SYK TRIB1 0 0 0 162 1 1
SYK GNAS 0 0 96 289 1 1
SYK NMRK2 0 0 0 175 1 1
SYK GDF2 0 0 59 200 1 1
SYK CASP9 0 0 199 298 1 2
SYK ITPR1 0 650 294 746 1 2
SYK TLR7 0 0 503 585 1 2
SYK MAPK9 0 0 294 229 1 2
SYK RPS6KA3 0 0 194 181 1 1
SYK CD59 0 0 136 190 1 1
SYK SLIT1 0 0 47 151 1 1
SYK PRKAB2 0 0 53 154 1 1
SYK MS4A7 0 0 0 211 1 1
SYK IL17A 0 0 518 519 1 2
SYK ETS1 0 0 166 182 1 1
SYK SOS2 0 0 136 243 1 1
SYK ARL11 0 0 0 202 1 1
SYK CPA3 0 0 95 168 1 1
SYK CLEC2A 0 0 138 153 1 1
SYK SHANK2 0 0 0 180 1 1
SYK IGHV4-38-2 0 800 528 901 1 1
SYK BCL11A 0 0 113 202 1 1
SYK SKP2 0 0 90 165 1 2
SYK ARG1 0 0 206 242 1 2
SYK GRB7 0 0 150 154 1 1
SYK CD79B 462 900 909 995 1 1
SYK BCKDK 0 0 0 197 1 1
SYK FOXP1 0 0 137 206 1 1
SYK HLA-DQA1 0 0 134 206 1 1
SYK RAPGEF1 0 0 151 222 1 1
SYK GRAPL 0 0 0 191 1 1
SYK TBXA2R 0 900 125 911 1 1
SYK TNS1 0 0 187 278 1 1
SYK STIM2 0 0 149 202 1 1
SYK PXN 270 0 403 565 1 1
SYK HIST2H3PS2 0 0 170 190 1 1
SYK HSPA6 0 0 0 179 1 1
SYK SPRED3 0 0 0 184 1 1
SYK IFIH1 0 0 271 308 1 1
SYK CSK 0 0 612 207 1 1
SYK RCSD1 0 0 49 156 1 1
SYK RPS6KB2 270 0 0 323 1 2
SYK OMG 0 0 0 154 1 1
SYK KLRF1 0 0 265 313 1 1
SYK FKBP1A 0 0 141 165 1 2
SYK NR3C1 0 0 143 175 1 1
SYK IL2RG 0 900 218 934 1 1
SYK PRF1 0 0 340 384 1 1
SYK CISH 0 0 261 333 1 1
SYK CD244 0 0 253 366 1 1
SYK PTGER4 0 0 112 157 1 1
SYK GRN 0 0 75 151 1 1
SYK TICAM1 270 0 243 494 1 2
SYK IL17RA 270 0 456 607 1 1
SYK CCRL2 0 0 194 320 1 1
SYK NME4 0 0 66 185 1 1
SYK CD37 270 0 300 549 1 1
SYK YWHAE 0 0 52 174 1 1
SYK VCP 0 0 102 174 1 2
SYK LCK 775 900 914 983 1 1
SYK MIB2 0 0 69 229 1 1
SYK CD69 0 0 467 516 1 1
SYK CSTA 0 0 0 156 1 1
SYK P2RY12 0 0 391 390 1 1
SYK IL37 0 0 123 161 1 1
SYK CCR5 0 0 220 364 1 1
SYK DUSP22 0 0 210 273 1 1
SYK DCSTAMP 0 0 298 319 1 1
SYK CSNK1A1 0 0 95 185 1 1
SYK FCRLA 0 0 266 320 1 1
SYK HAVCR2 270 0 231 465 1 1
SYK OSCAR 0 600 342 752 1 1
SYK CALR 0 0 193 205 1 1
SYK EXOC7 0 0 0 179 1 1
SYK FKBP14 0 0 0 153 1 1
SYK CD8A 0 900 563 958 1 1
SYK ADAM8 0 0 76 202 1 1
SYK SIGLEC7 0 0 310 401 1 1
SYK CRK 0 600 408 761 1 1
SYK LIMK2 0 0 0 154 1 1
SYK RIPK2 0 0 265 219 1 2
SYK FAM129C 0 0 143 175 1 1
SYK TNFSF4 0 0 247 246 1 1
SYK RASD1 0 0 92 185 1 1
SYK TNFRSF8 0 0 240 259 1 1
SYK ANGPT2 0 0 95 150 1 1
SYK CHST12 0 0 123 187 1 1
SYK SLAMF1 0 0 284 352 1 1
SYK AGRN 0 0 45 191 1 1
SYK MMP2 0 0 163 163 1 2
SYK MORN2 0 0 63 165 1 1
SYK PLAT 0 0 157 229 1 1
SYK SNCA 213 900 106 924 1 2
SYK CD74 0 0 288 398 1 1
SYK CD27 0 0 402 439 1 1
SYK CHEK1 0 0 181 153 1 2
SYK EVI2B 0 0 0 163 1 1
SYK CASP1 270 0 520 715 1 2
SYK CCR3 0 0 142 194 1 1
SYK HSPA1A 0 0 73 169 1 1
SYK HLA-DRB1 0 0 94 208 1 1
SYK CAV1 0 0 207 221 1 2
SYK TNFSF10 0 0 171 221 1 2
SYK MAP2K3 0 0 245 152 1 1
SYK PLS1 0 0 411 448 1 1
SYK VRK2 0 0 64 184 1 1
SYK ARL17B 0 0 0 157 1 1
SYK DPP9 270 0 90 313 1 1
SYK IL10RA 0 0 183 394 1 1
SYK TNKS 0 0 204 568 1 1
SYK BCL2L11 0 0 324 349 1 2
SYK MAPK12 0 0 134 191 1 1
SYK SERPINA1 0 0 97 168 1 2
SYK CCL24 0 0 69 190 1 1
SYK SIGLEC1 0 0 234 306 1 1
SYK PLCG1 932 900 974 996 1 1
SYK BATF 0 0 112 241 1 1
SYK ITPR3 0 650 294 746 1 1
SYK MAFB 0 0 109 182 1 1
SYK GP1BA 0 0 420 465 1 1
SYK TNIP3 0 0 157 170 1 1
SYK DVL3 0 0 60 180 1 1
SYK RPL7 0 0 0 566 1 1
SYK HPGDS 0 0 520 548 1 1
SYK IL3 0 0 469 469 1 1
SYK TFEB 0 0 60 159 1 2
SYK SLAMF6 0 0 235 307 1 1
SYK DYRK2 0 0 62 153 1 1
SYK MYO1G 0 0 0 246 1 1
SYK LAIR1 0 0 270 382 1 1
SYK CEBPA 0 0 139 214 1 1
SYK XCL2 0 0 0 202 1 1
SYK CD8B 0 900 213 919 1 1
SYK FPR2 0 0 167 226 1 1
SYK THEMIS2 0 0 0 204 1 1
SYK ITGB7 0 0 167 368 1 1
SYK CD40 0 0 561 610 1 2
SYK CTTN 632 0 661 876 1 1
SYK STUB1 0 0 97 155 1 2
SYK DNMT1 0 0 155 173 1 2
SYK INS 0 0 285 284 1 2
SYK ACTB 0 0 504 548 1 2
SYK GLI3 0 0 61 188 1 1
SYK KIR3DL3 0 0 171 205 1 1
SYK GRASP 270 0 92 370 1 1
SYK FCGR2B 0 600 604 857 1 1
SYK PAX5 0 0 413 463 1 1
SYK B2M 0 600 218 689 1 1
SYK ANGPT1 0 0 90 169 1 1
SYK HSPA8 0 0 97 186 1 2
SYK RHOA 0 650 459 822 1 2
SYK LLGL2 0 0 0 197 1 1
SYK SLC39A10 0 0 124 176 1 1
SYK JUP 0 0 0 194 1 1
SYK TNFRSF14 0 0 218 263 1 1
SYK UBE2N 0 0 107 185 1 1
SYK RHOQ 0 0 323 392 1 1
SYK CXCL12 0 0 394 394 1 2
SYK TLR5 0 0 370 436 1 1
SYK CD3D 0 900 266 929 1 1
SYK KLRK1 0 0 469 512 1 1
SYK PLA2G1B 0 0 162 161 1 1
SYK FYB 0 0 450 533 1 1
SYK RHOG 0 650 396 806 1 1
SYK NIM1K 0 0 0 158 1 1
SYK CBLC 0 0 171 271 1 1
SYK SEMA4A 0 0 85 171 1 1
SYK UNC93B1 0 0 234 329 1 1
SYK PBX1 0 0 183 189 1 1
SYK PDK2 0 0 0 197 1 1
SYK MS4A1 0 0 135 287 1 1
SYK PEAR1 270 0 108 368 1 1
SYK IL22 0 0 230 229 1 1
SYK MYH9 0 0 154 231 1 1
SYK CD24 0 0 236 236 1 2
SYK BTLA 0 0 189 319 1 1
SYK RAB12 0 0 0 199 1 2
SYK VAV2 500 900 696 984 1 1
SYK MPO 0 0 321 392 1 2
SYK IL3RA 0 0 260 306 1 1
SYK BRMS1L 0 0 108 187 1 1
SYK LYZ 0 0 47 224 1 1
SYK LYVE1 0 0 171 256 1 1
SYK FRAT2 0 0 0 163 1 1
SYK F11R 0 0 450 470 1 1
SYK IL6 0 0 609 632 1 2
SYK ACTR2 0 0 171 212 1 1
SYK TNFRSF1A 462 0 474 720 1 1
SYK RPS6 0 0 149 210 1 2
SYK TRAF4 0 0 233 300 1 1
SYK NOC2L 0 0 0 219 1 1
SYK PIDD1 0 0 0 181 1 1
SYK PSEN2 0 0 91 151 1 1
SYK VPREB1 0 0 414 414 1 1
SYK PTPN13 0 0 95 155 1 1
SYK NOTCH1 0 0 310 352 1 2
SYK ENTPD1 0 0 142 201 1 1
SYK SULT1A1 0 0 0 204 1 1
SYK PTGS1 0 0 163 231 1 1
SYK CD40LG 0 0 504 566 1 1
SYK THEMIS 0 0 149 183 1 1
SYK NLRP1 0 0 290 305 1 1
SYK RHOU 270 0 390 583 1 1
SYK MYO9B 0 0 107 226 1 1
SYK TRPV6 0 0 0 202 1 1
SYK PTPRU 0 0 122 193 1 1
SYK POTEF 0 0 130 208 1 1
SYK CALM1 488 0 113 568 1 1
SYK C4A 0 0 150 237 1 1
SYK FCGR3A 270 900 467 963 1 1
SYK CDK2 0 0 219 155 1 2
SYK SOCS7 0 0 155 229 1 1
SYK FCRL4 0 0 260 271 1 1
SYK FCRL3 270 0 740 821 1 1
SYK PLA2G4A 0 900 324 936 1 1
SYK IBTK 0 900 150 912 1 1
SYK CXCR2 0 0 251 296 1 1
SYK CSNK1G1 0 0 88 167 1 1
SYK TNFRSF1B 0 0 122 211 1 1
SYK CCBE1 0 0 77 262 1 1
SYK PACS2 0 0 202 524 1 1
SYK SH2B2 213 0 0 274 1 1
SYK MS4A4A 0 0 0 158 1 1
SYK B7RP1 0 0 202 220 1 1
SYK XPO1 0 0 134 205 1 1
SYK SAMSN1 0 0 74 224 1 1
SYK TRPM7 0 0 167 177 1 1
SYK PRKCB 0 0 623 341 1 2
SYK SIGLEC12 0 0 125 213 1 1
SYK HIF1A 0 0 240 262 1 2
SYK TRAF5 0 0 212 281 1 1
SYK HCLS1 600 900 246 975 1 1
SYK SP1 270 0 134 375 1 2
SYK IL1B 0 0 603 632 1 2
SYK STAB1 0 0 74 200 1 1
SYK IGLL1 0 360 391 603 1 1
SYK RNF11 0 0 304 337 1 1
SYK MAPK13 0 0 46 180 1 1
SYK KCNQ1 0 0 0 172 1 1
SYK DOK7 0 0 0 175 1 1
SYK NCR3 0 0 390 419 1 1
SYK ADAP2 0 0 0 170 1 1
SYK NCR1 0 0 392 398 1 1
SYK DOCK1 0 600 180 680 1 1
SYK SMAD2 0 0 142 218 1 2
SYK EMR1 0 0 0 163 1 1
SYK TLR4 462 0 988 994 1 2
SYK PHKA2 0 0 125 157 1 1
SYK GP9 0 0 262 354 1 1
SYK SH2B3 0 0 166 218 1 1
SYK TNFRSF25 0 0 107 179 1 1
SYK EGR3 0 0 167 201 1 1
SYK ABCF1 270 0 0 288 1 1
SYK RPS6KA5 0 0 108 163 1 1
SYK CD14 0 0 46 285 1 1
SYK GAPT 0 0 67 221 1 1
SYK RAP1A 0 600 181 696 1 1
SYK GABARAPL2 0 0 64 179 1 2
SYK NF1 0 0 123 227 1 1
SYK CLIC6 0 0 0 159 1 1
SYK NOS2 0 0 323 353 1 2
SYK KITLG 0 0 344 367 1 1
SYK CALCR 0 0 217 260 1 1
SYK LONRF2 0 0 0 200 1 1
SYK CLEC7A 0 800 989 997 1 1
SYK ITPR2 0 650 141 692 1 1
SYK ENSG00000250349 0 0 261 275 1 1
SYK SH2D1B 0 0 501 521 1 1
SYK FBXO42 0 0 0 187 1 1
SYK PHLPP1 0 0 396 424 1 2
SYK TAB3 0 0 92 151 1 1
SYK C1R 0 0 92 162 1 1
SYK DNMT3A 0 0 181 181 1 2
SYK TEC 0 500 296 576 1 1
SYK BCL2L1 0 0 451 451 1 2
SYK AOC3 0 0 293 293 1 1
SYK CCL4L1 0 0 234 253 1 1
SYK ANXA5 0 0 392 392 1 2
SYK CCNB1 0 0 142 207 1 1
SYK NPPA 0 0 451 451 1 1
SYK GRIA2 0 0 0 165 1 1
SYK GRIA4 0 0 0 222 1 1
SYK LGALS9 0 0 162 287 1 1
SYK FOXM1 0 0 90 173 1 1
SYK TAGLN 0 0 73 165 1 1
SYK MGMT 0 0 207 208 1 2
SYK HSPD1 0 0 93 187 1 1
SYK CLEC4D 0 0 667 699 1 1
SYK PDP2 0 0 0 225 1 1
SYK PLK1 0 0 253 159 1 2
SYK CXCL13 0 0 324 339 1 1
SYK TNFSF9 0 0 134 163 1 1
SYK PLEC 0 0 70 196 1 1
SYK TENC1 0 0 161 266 1 1
SYK MAPK4 0 0 0 154 1 1
SYK ARHGEF6 0 0 47 165 1 1
SYK GRB10 0 0 145 181 1 1
SYK SIRPB1 270 0 425 593 1 1
SYK ARF1 0 0 91 219 1 1
SYK GPR18 0 0 0 169 1 1
SYK IFNG 0 0 261 422 1 2
SYK BIRC2 0 0 171 252 1 1
SYK GAST 0 0 0 153 1 1
SYK PLCG2 462 900 964 976 1 1
SYK TNFRSF17 0 0 220 239 1 1
SYK TGFB3 0 0 74 179 1 1
SYK CCL5 0 0 360 404 1 2
SYK HCST 0 0 741 790 1 1
SYK TLR1 0 0 400 520 1 1
SYK BACH2 0 0 150 223 1 1
SYK NFE2L2 0 0 95 151 1 2
SYK MAP2K5 0 0 81 199 1 1
SYK AKT2 0 0 243 157 1 2
SYK PPP1R13B 0 0 113 166 1 1
SYK UCK1 0 0 0 194 1 1
SYK ENSG00000272772 0 0 0 166 1 1
SYK UNC13D 0 0 125 186 1 1
SYK UBE2K 0 0 210 232 1 1
SYK FKBP7 0 0 61 170 1 1
SYK NLRP12 0 0 171 192 1 1
SYK CD80 0 0 426 466 1 2
SYK FURIN 0 0 113 235 1 1
SYK GP1BB 0 0 276 322 1 1
SYK ASGR1 0 0 150 177 1 1
SYK IKZF3 0 0 218 321 1 1
SYK DHX58 0 0 142 182 1 1
SYK OSM 0 0 108 198 1 1
SYK MFF 0 0 0 183 1 1
SYK VASP 0 0 261 458 1 1
SYK MAP2K1 0 0 401 308 1 1
SYK CARD10 0 0 193 223 1 1
SYK HDAC3 270 0 49 304 1 2
SYK MYCN 0 0 134 183 1 1
SYK PPP3CC 0 0 45 158 1 1
SYK SMAD4 0 0 150 225 1 2
SYK S1PR2 0 0 161 179 1 1
SYK CIDEB 0 0 144 173 1 1
SYK NCKAP1L 0 0 161 384 1 1
SYK UBA1 0 0 0 173 1 1
SYK MPEG1 0 0 0 238 1 1
SYK TNFRSF13B 0 0 317 352 1 1
SYK SHANK1 0 0 0 180 1 1
SYK STXBP6 0 0 0 167 1 1
SYK EFNA5 0 0 0 168 1 1
SYK DENND1C 0 0 0 203 1 1
SYK ARRDC2 0 0 0 169 1 1
SYK TRAF2 0 0 143 230 1 2
SYK SLC7A1 0 0 0 150 1 1
SYK GNAT3 0 0 0 171 1 1
SYK TAB1 0 0 184 319 1 1
SYK MX1 0 0 171 224 1 1
SYK PPP3CB 0 0 68 179 1 1
SYK CD300A 0 0 277 380 1 1
SYK CERS1 0 0 0 156 1 1
SYK GNAT2 0 0 0 171 1 1
SYK PIK3CA 0 900 334 937 1 2
SYK PLCB2 0 0 137 337 1 1
SYK EFNA4 0 0 45 171 1 1
SYK SIGLEC11 0 0 242 309 1 1
SYK IL1R1 0 0 378 387 1 1
SYK CLECL1 0 0 136 232 1 1
SYK PDK1 0 0 77 228 1 2
SYK MYC 0 0 579 590 1 2
SYK PPIP5K1 0 0 0 344 1 1
SYK IL18 0 0 468 501 1 2
SYK SLC6A4 0 0 444 456 1 1
SYK HOXA9 0 0 142 158 1 1
SYK PLCB3 0 0 0 171 1 1
SYK TAB2 0 0 193 246 1 2
SYK SLAMF7 0 0 209 302 1 1
SYK ITGAD 0 0 170 225 1 1
SYK GPSM3 0 0 0 161 1 1
SYK CD84 0 0 146 263 1 1
SYK TREM1 0 0 522 586 1 1
SYK LILRA1 0 600 157 694 1 1
SYK PI3 0 0 283 282 1 2
SYK TRIM23 0 0 44 171 1 1
SYK GATA3 0 0 264 344 1 1
SYK ENPP3 0 0 217 247 1 1
SYK MKKS 0 0 134 295 1 1
SYK STAT3 873 0 722 967 1 2
SYK EZH2 0 0 181 204 1 2
SYK SPIC 0 0 174 214 1 1
SYK KDM7A 0 0 0 156 1 1
SYK HLA-DQB1 0 0 61 207 1 1
SYK SNX22 0 0 70 241 1 1
SYK FCER2 0 0 233 323 1 1
SYK CAMKK2 0 0 123 153 1 2
SYK CYBA 0 0 209 259 1 1
SYK FGR 500 900 745 967 1 1
SYK LY86 0 0 51 259 1 1
SYK BAZ2A 0 0 53 154 1 1
SYK HGS 270 0 305 521 1 2
SYK SH3BP5 0 900 181 920 1 1
SYK TXK 0 500 454 590 1 1
SYK CSF3 0 0 341 341 1 1
SYK LMNA 0 0 181 208 1 2
SYK SNAP23 0 0 173 202 1 1
SYK CEACAM20 0 0 448 460 1 1
SYK CAMP 0 0 211 251 1 2
SYK TRAF1 0 0 208 297 1 1
SYK SLMAP 0 0 0 226 1 1
SYK SELPLG 213 0 701 770 1 1
SYK KLHDC2 0 0 49 167 1 1
SYK KIR3DL2 0 0 215 266 1 1
SYK LCP2 462 800 959 996 1 1
SYK ORAI1 0 0 271 337 1 1
SYK RASGRP2 0 0 281 396 1 1
SYK KLRC1 0 0 391 395 1 1
SYK TUBA4A 213 0 0 237 1 1
SYK IRF9 0 0 134 158 1 1
SYK CFTR 0 0 181 204 1 2
SYK SARM1 0 0 150 166 1 1
SYK RAB4A 0 0 165 251 1 1
SYK ESX1 0 0 181 211 1 1
SYK FADD 0 0 211 251 1 2
SYK CDK4 0 0 245 167 1 2
SYK PSTPIP1 0 0 161 276 1 1
SYK FES 0 0 391 289 1 1
SYK MYD88 270 0 780 868 1 2
SYK ADORA3 0 0 150 204 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0005524 Molecular Function ATP binding enables IEA
GO:0042169 Molecular Function SH2 domain binding enables IEA
GO:0035325 Molecular Function Toll-like receptor binding enables IEA
GO:0005178 Molecular Function integrin binding enables IPI
GO:0016170 Molecular Function interleukin-15 receptor binding enables IPI
GO:0016301 Molecular Function kinase activity enables IDA
GO:0016301 Molecular Function kinase activity enables ISS
GO:0004715 Molecular Function non-membrane spanning protein tyrosine kinase activity enables IBA
GO:0004715 Molecular Function non-membrane spanning protein tyrosine kinase activity enables IDA
GO:0004715 Molecular Function non-membrane spanning protein tyrosine kinase activity enables IGI
GO:0004715 Molecular Function non-membrane spanning protein tyrosine kinase activity enables TAS
GO:0019902 Molecular Function phosphatase binding enables IEA
GO:0043274 Molecular Function phospholipase binding enables IPI
GO:0001784 Molecular Function phosphotyrosine residue binding enables IMP
GO:0001784 Molecular Function phosphotyrosine residue binding enables IPI
GO:0005515 Molecular Function protein binding enables IPI
GO:0004672 Molecular Function protein kinase activity enables IDA
GO:0004672 Molecular Function protein kinase activity enables NAS
GO:0019901 Molecular Function protein kinase binding enables IEA
GO:0004674 Molecular Function protein serine/threonine kinase activity enables IDA
GO:0004713 Molecular Function protein tyrosine kinase activity enables EXP
GO:0004713 Molecular Function protein tyrosine kinase activity enables IDA
GO:0004713 Molecular Function protein tyrosine kinase activity enables IMP
GO:0004713 Molecular Function protein tyrosine kinase activity enables NAS
GO:0004713 Molecular Function protein tyrosine kinase activity enables TAS
GO:0097110 Molecular Function scaffold protein binding enables IPI
GO:0005102 Molecular Function signaling receptor binding enables IBA
GO:0005102 Molecular Function signaling receptor binding enables IPI
GO:0030183 Biological Process B cell differentiation involved_in IEA
GO:0050853 Biological Process B cell receptor signaling pathway involved_in IBA
GO:0050853 Biological Process B cell receptor signaling pathway involved_in IMP
GO:0050853 Biological Process B cell receptor signaling pathway involved_in ISS
GO:0038095 Biological Process Fc-epsilon receptor signaling pathway involved_in TAS
GO:0038096 Biological Process Fc-gamma receptor signaling pathway involved in phagocytosis involved_in TAS
GO:0002250 Biological Process adaptive immune response involved_in IBA
GO:0002250 Biological Process adaptive immune response involved_in ISS
GO:0001525 Biological Process angiogenesis involved_in IEA
GO:0009887 Biological Process animal organ morphogenesis involved_in TAS
GO:0043366 Biological Process beta selection involved_in IEA
GO:0048514 Biological Process blood vessel morphogenesis involved_in ISS
GO:0019722 Biological Process calcium-mediated signaling involved_in IEA
GO:0001775 Biological Process cell activation involved_in ISS
GO:0030154 Biological Process cell differentiation involved_in IBA
GO:1990858 Biological Process cellular response to lectin involved_in ISS
GO:0071396 Biological Process cellular response to lipid involved_in IMP
GO:0071404 Biological Process cellular response to low-density lipoprotein particle stimulus involved_in ISS
GO:0071226 Biological Process cellular response to molecule of fungal origin involved_in ISS
GO:0038063 Biological Process collagen-activated tyrosine kinase receptor signaling pathway involved_in IEA
GO:0042742 Biological Process defense response to bacterium involved_in ISS
GO:0042492 Biological Process gamma-delta T cell differentiation involved_in IEA
GO:0045087 Biological Process innate immune response involved_in IBA
GO:0045087 Biological Process innate immune response involved_in ISS
GO:0007229 Biological Process integrin-mediated signaling pathway involved_in ISS
GO:0007229 Biological Process integrin-mediated signaling pathway involved_in NAS
GO:0038156 Biological Process interleukin-3-mediated signaling pathway involved_in ISS
GO:0035556 Biological Process intracellular signal transduction involved_in IDA
GO:0035556 Biological Process intracellular signal transduction involved_in IGI
GO:0035556 Biological Process intracellular signal transduction involved_in IMP
GO:0035556 Biological Process intracellular signal transduction involved_in ISS
GO:0002366 Biological Process leukocyte activation involved in immune response involved_in ISS
GO:0007159 Biological Process leukocyte cell-cell adhesion involved_in IDA
GO:0019370 Biological Process leukotriene biosynthetic process involved_in IEA
GO:0001945 Biological Process lymph vessel development involved_in ISS
GO:0002281 Biological Process macrophage activation involved in immune response involved_in IBA
GO:0002281 Biological Process macrophage activation involved in immune response involved_in ISS
GO:0043303 Biological Process mast cell degranulation involved_in IEA
GO:0002862 Biological Process negative regulation of inflammatory response to antigenic stimulus involved_in TAS
GO:0002283 Biological Process neutrophil activation involved in immune response involved_in IBA
GO:0002283 Biological Process neutrophil activation involved in immune response involved_in ISS
GO:0030593 Biological Process neutrophil chemotaxis involved_in IDA
GO:0018108 Biological Process peptidyl-tyrosine phosphorylation involved_in IDA
GO:0018108 Biological Process peptidyl-tyrosine phosphorylation involved_in IGI
GO:0018108 Biological Process peptidyl-tyrosine phosphorylation involved_in IMP
GO:0018108 Biological Process peptidyl-tyrosine phosphorylation involved_in ISS
GO:0030168 Biological Process platelet activation involved_in TAS
GO:0045579 Biological Process positive regulation of B cell differentiation involved_in IBA
GO:0045579 Biological Process positive regulation of B cell differentiation involved_in IMP
GO:0043410 Biological Process positive regulation of MAPK cascade involved_in IEA
GO:1904263 Biological Process positive regulation of TORC1 signaling involved_in IDA
GO:0046638 Biological Process positive regulation of alpha-beta T cell differentiation involved_in IEA
GO:0046641 Biological Process positive regulation of alpha-beta T cell proliferation involved_in IBA
GO:0045780 Biological Process positive regulation of bone resorption involved_in ISS
GO:0050850 Biological Process positive regulation of calcium-mediated signaling involved_in IEA
GO:0033630 Biological Process positive regulation of cell adhesion mediated by integrin involved_in IBA
GO:0033630 Biological Process positive regulation of cell adhesion mediated by integrin involved_in ISS
GO:0120162 Biological Process positive regulation of cold-induced thermogenesis involved_in ISS
GO:0043280 Biological Process positive regulation of cysteine-type endopeptidase activity involved in apoptotic process involved_in IMP
GO:0045588 Biological Process positive regulation of gamma-delta T cell differentiation involved_in IEA
GO:0032725 Biological Process positive regulation of granulocyte macrophage colony-stimulating factor production involved_in IEA
GO:0032733 Biological Process positive regulation of interleukin-10 production involved_in IMP
GO:0032735 Biological Process positive regulation of interleukin-12 production involved_in IMP
GO:0032752 Biological Process positive regulation of interleukin-3 production involved_in IEA
GO:0032753 Biological Process positive regulation of interleukin-4 production involved_in ISS
GO:0032755 Biological Process positive regulation of interleukin-6 production involved_in IMP
GO:0032757 Biological Process positive regulation of interleukin-8 production involved_in IMP
GO:0051712 Biological Process positive regulation of killing of cells of another organism involved_in IMP
GO:0032765 Biological Process positive regulation of mast cell cytokine production involved_in IEA
GO:0043306 Biological Process positive regulation of mast cell degranulation involved_in IBA
GO:0071639 Biological Process positive regulation of monocyte chemotactic protein-1 production involved_in IMP
GO:0050731 Biological Process positive regulation of peptidyl-tyrosine phosphorylation involved_in IEA
GO:0031334 Biological Process positive regulation of protein-containing complex assembly involved_in IMP
GO:0002092 Biological Process positive regulation of receptor internalization involved_in IEA
GO:0032930 Biological Process positive regulation of superoxide anion generation involved_in IMP
GO:0032760 Biological Process positive regulation of tumor necrosis factor production involved_in IMP
GO:0032481 Biological Process positive regulation of type I interferon production involved_in IEA
GO:0006606 Biological Process protein import into nucleus acts_upstream_of_or_within IMP
GO:0006468 Biological Process protein phosphorylation involved_in IBA
GO:0006468 Biological Process protein phosphorylation involved_in IDA
GO:0031623 Biological Process receptor internalization involved_in ISS
GO:0051090 Biological Process regulation of DNA-binding transcription factor activity acts_upstream_of_or_within IMP
GO:0070372 Biological Process regulation of ERK1 and ERK2 cascade involved_in ISS
GO:0090237 Biological Process regulation of arachidonic acid secretion involved_in ISS
GO:0043313 Biological Process regulation of neutrophil degranulation involved_in ISS
GO:0050764 Biological Process regulation of phagocytosis involved_in ISS
GO:0010543 Biological Process regulation of platelet activation involved_in ISS
GO:0090330 Biological Process regulation of platelet aggregation involved_in IBA
GO:0090330 Biological Process regulation of platelet aggregation involved_in ISS
GO:0032928 Biological Process regulation of superoxide anion generation involved_in ISS
GO:0010803 Biological Process regulation of tumor necrosis factor-mediated signaling pathway involved_in IMP
GO:0002554 Biological Process serotonin secretion by platelet involved_in ISS
GO:0002223 Biological Process stimulatory C-type lectin receptor signaling pathway involved_in ISS
GO:0002223 Biological Process stimulatory C-type lectin receptor signaling pathway involved_in TAS
GO:0007169 Biological Process transmembrane receptor protein tyrosine kinase signaling pathway involved_in IBA
GO:0019815 Cellular Component B cell receptor complex part_of IEA
GO:0042101 Cellular Component T cell receptor complex part_of IDA
GO:0005737 Cellular Component cytoplasm located_in IDA
GO:0005737 Cellular Component cytoplasm is_active_in ISS
GO:0005829 Cellular Component cytosol located_in IC
GO:0005829 Cellular Component cytosol located_in TAS
GO:0032009 Cellular Component early phagosome located_in ISS
GO:0031234 Cellular Component extrinsic component of cytoplasmic side of plasma membrane is_active_in IBA
GO:0005634 Cellular Component nucleus located_in IDA
GO:0005886 Cellular Component plasma membrane located_in TAS
GO:0032991 Cellular Component protein-containing complex part_of IDA
Pathways
Name DB ID
Hemostasis Reactome R-HSA-109582
GPVI-mediated activation cascade Reactome R-HSA-114604
Cytokine Signaling in Immune system Reactome R-HSA-1280215
Adaptive Immune System Reactome R-HSA-1280218
Signal Transduction Reactome R-HSA-162582
Disease Reactome R-HSA-1643685
Innate Immune System Reactome R-HSA-168249
Immune System Reactome R-HSA-168256
Fcgamma receptor (FCGR) dependent phagocytosis Reactome R-HSA-2029480
FCGR activation Reactome R-HSA-2029481
Regulation of actin dynamics for phagocytic cup formation Reactome R-HSA-2029482
Role of phospholipids in phagocytosis Reactome R-HSA-2029485
DAP12 interactions Reactome R-HSA-2172127
DAP12 signaling Reactome R-HSA-2424491
Fc epsilon receptor (FCERI) signaling Reactome R-HSA-2454202
Role of LAT2/NTAL/LAB on calcium mobilization Reactome R-HSA-2730905
FCERI mediated MAPK activation Reactome R-HSA-2871796
FCERI mediated Ca+2 mobilization Reactome R-HSA-2871809
Integrin signaling Reactome R-HSA-354192
Signaling by Interleukins Reactome R-HSA-449147
Interleukin-2 family signaling Reactome R-HSA-451927
Interleukin-3, Interleukin-5 and GM-CSF signaling Reactome R-HSA-512988
CLEC7A (Dectin-1) signaling Reactome R-HSA-5607764
Dectin-2 family Reactome R-HSA-5621480
C-type lectin receptors (CLRs) Reactome R-HSA-5621481
Infectious disease Reactome R-HSA-5663205
Platelet activation, signaling and aggregation Reactome R-HSA-76002
Platelet Aggregation (Plug Formation) Reactome R-HSA-76009
Interleukin-2 signaling Reactome R-HSA-9020558
Regulation of signaling by CBL Reactome R-HSA-912631
FLT3 Signaling Reactome R-HSA-9607240
Leishmania infection Reactome R-HSA-9658195
Anti-inflammatory response favouring Leishmania parasite infection Reactome R-HSA-9662851
FCGR3A-mediated IL10 synthesis Reactome R-HSA-9664323
Parasite infection Reactome R-HSA-9664407
Leishmania phagocytosis Reactome R-HSA-9664417
FCGR3A-mediated phagocytosis Reactome R-HSA-9664422
Leishmania parasite growth and survival Reactome R-HSA-9664433
Signaling by CSF3 (G-CSF) Reactome R-HSA-9674555
Potential therapeutics for SARS Reactome R-HSA-9679191
SARS-CoV Infections Reactome R-HSA-9679506
Inactivation of CSF3 (G-CSF) signaling Reactome R-HSA-9705462
FLT3 signaling through SRC family kinases Reactome R-HSA-9706374
Parasitic Infection Pathways Reactome R-HSA-9824443
Viral Infection Pathways Reactome R-HSA-9824446
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers Reactome R-HSA-983695
Signaling by the B Cell Receptor (BCR) Reactome R-HSA-983705
Extrafollicular and follicular B cell activation by SARS-CoV-2 (WP5218) WikiPathways WP5218_r124690
IL-3 signaling pathway (WP286) WikiPathways WP286_r120663
IL-5 signaling pathway (WP127) WikiPathways WP127_r120669
Microglia pathogen phagocytosis pathway (WP3937) WikiPathways WP3937_r120792
IL-2 signaling pathway (WP49) WikiPathways WP49_r120703
B cell receptor signaling pathway (WP23) WikiPathways WP23_r120701
RANKL/RANK signaling pathway (WP2018) WikiPathways WP2018_r120672
Fibrin complement receptor 3 signaling pathway (WP4136) WikiPathways WP4136_r120387
PI3K-Akt signaling pathway (WP4172) WikiPathways WP4172_r122580
Transcripts
Accession Version MolecularType Name NCBI Comments
XM_011518946 4 mRNA transcript variant X2 NC_000009 Reference
NM_001174168 3 mRNA transcript variant 4 NC_000009 Reference
XM_047423809 1 mRNA transcript variant X5 NC_000009 Reference
XM_005252147 5 mRNA transcript variant X1 NC_000009 Reference
XM_047423810 1 mRNA transcript variant X3 NC_000009 Reference
NM_003177 7 mRNA transcript variant 1 NC_000009 Reference
NM_001135052 4 mRNA transcript variant 2 NC_000009 Reference
XM_047423811 1 mRNA transcript variant X4 NC_000009 Reference
NM_001174167 3 mRNA transcript variant 3 NC_000009 Reference