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TLR3

toll like receptor 3
General Information
Name toll like receptor 3
Alias
  • toll-like receptor 3
Gene_family Toll like receptors|CD molecules
organism Homo sapiens
entrez_id 7098
location 4q35.1
transcript_count 1
exon_count 5
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It thus plays a role in host defense against multiple viruses. [provided by RefSeq, Jul 2021]
    Stringdb Toll-like receptor 3; Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response; CD molecules
    nextProt Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response.
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
TLR3 BioGRID RNF115 GeneID BioGRID Affinity Capture-Western
TLR3 BioGRID CISD2 GeneID BioGRID Affinity Capture-MS
TLR3 BioGRID CNOT6L GeneID BioGRID Affinity Capture-MS
TLR3 BioGRID LRRC40 GeneID BioGRID Affinity Capture-MS
TLR3 BioGRID PIGH GeneID BioGRID Affinity Capture-MS
TLR3 BioGRID BLK GeneID BioGRID Affinity Capture-MS
TLR3 BioGRID ATP2A3 GeneID BioGRID Affinity Capture-MS
TLR3 BioGRID RBM39 GeneID BioGRID Affinity Capture-MS
TLR3 BioGRID NPC1 GeneID BioGRID Affinity Capture-MS
TLR3 BioGRID UNC93B1 GeneID BioGRID Affinity Capture-Western
TLR3 BioGRID TICAM1 GeneID BioGRID Affinity Capture-Western
TLR3 BioGRID RNF170 GeneID BioGRID Affinity Capture-Western; Co-localization; Reconstituted Complex
TLR3 BioGRID KCND3 GeneID BioGRID Affinity Capture-Western
TLR3 BioGRID KCND2 GeneID BioGRID Affinity Capture-Western
TLR3 BioGRID VIRMA GeneID BioGRID Affinity Capture-RNA
TLR3 BioGRID RNF123 GeneID BioGRID Affinity Capture-MS
TLR3 BioGRID SHARPIN GeneID BioGRID Affinity Capture-Western
TLR3 BioGRID RNF31 GeneID BioGRID Affinity Capture-Western
TLR3 BioGRID TBK1 GeneID BioGRID Affinity Capture-Western
TLR3 BioGRID RBCK1 GeneID BioGRID Affinity Capture-Western
TLR3 BioGRID FADD GeneID BioGRID Affinity Capture-Western
TLR3 BioGRID RIPK1 GeneID BioGRID Affinity Capture-Western
TLR3 BioGRID IKBKG GeneID BioGRID Affinity Capture-Western
TLR3 BioGRID TRAF6 GeneID BioGRID Affinity Capture-Western
TLR3 BioGRID CASP8 GeneID BioGRID Affinity Capture-Western
TLR3 BioGRID BIRC3 GeneID BioGRID Affinity Capture-Western
TLR3 BioGRID BIRC2 GeneID BioGRID Affinity Capture-Western
TLR3 BioGRID IRGM GeneID BioGRID Affinity Capture-Western
TLR3 BioGRID WDFY1 GeneID BioGRID Affinity Capture-Western
TLR3 BioGRID HLA-DRA GeneID BioGRID Affinity Capture-Western; FRET
TLR3 BioGRID CHEK2 GeneID BioGRID Two-hybrid
TLR3 BioGRID SYK GeneID BioGRID Affinity Capture-Western
TLR3 BioGRID PIK3R1 GeneID BioGRID Affinity Capture-Western
TLR3 BioGRID MAP3K7 GeneID BioGRID Affinity Capture-Western
TLR3 BioGRID TAB2 GeneID BioGRID Affinity Capture-Western
TLR3 BioGRID MAP2K6 GeneID BioGRID Biochemical Activity
TLR3 BioGRID TOLLIP GeneID BioGRID Affinity Capture-MS
TLR3 BioGRID TRAF3 GeneID BioGRID Affinity Capture-MS
TLR3 BioGRID TRIM69 GeneID BioGRID Affinity Capture-Western
TLR3 Protein TICAM2 GeneID HPRD
TLR3 Protein RNF216 GeneID HPRD
TLR3 Protein TICAM1 GeneID HPRD
TLR3 Protein TLR3 GeneID HPRD
TLR3 Protein TRAF6 GeneID HPRD
TLR3 Protein MYD88 GeneID HPRD
TLR3 Protein CD14 GeneID HPRD
TLR3 Protein CSK GeneID HPRD
TLR3 BioGRID IRAK2 GeneID BioGRID Affinity Capture-Western
TLR3 BioGRID MYD88 GeneID BioGRID Reconstituted Complex
TLR3 BioGRID RNF216 GeneID BioGRID Two-hybrid
StringDB
A B experiments database textmining combined score hadb nhadb
TLR3 RBM8A 0 0 205 205 1 1
TLR3 EEF2 0 0 0 181 1 2
TLR3 RBFOX3 0 0 205 205 1 1
TLR3 RNF135 0 0 325 335 1 1
TLR3 NFAT5 0 0 96 183 1 1
TLR3 CLEC10A 0 0 165 178 1 1
TLR3 IFI27 0 0 284 299 1 1
TLR3 PRPF6 0 0 0 169 1 1
TLR3 NAIP 0 0 283 295 1 1
TLR3 VDR 0 0 228 254 1 2
TLR3 KCND2 270 0 0 270 1 1
TLR3 CGI-74 0 0 0 183 1 1
TLR3 MMP3 0 0 258 268 1 1
TLR3 IL1RN 0 0 335 335 1 1
TLR3 ECHDC2 0 0 0 177 1 1
TLR3 NT5E 0 0 266 278 1 1
TLR3 DCT 0 0 170 169 1 1
TLR3 MRPL15 0 0 0 165 1 1
TLR3 TNF 0 0 802 845 1 2
TLR3 BCAS2 0 0 0 179 1 1
TLR3 IFITM1 0 0 369 421 1 1
TLR3 MERTK 0 0 246 299 1 1
TLR3 SYF2 0 0 0 210 1 1
TLR3 ITIH4 0 0 334 348 1 1
TLR3 IRF7 0 600 835 951 1 1
TLR3 DDX53 0 0 217 266 1 1
TLR3 SOCS4 0 0 217 229 1 1
TLR3 CASK 0 0 0 171 1 1
TLR3 CDH5 0 0 135 188 1 1
TLR3 LSM8 0 0 0 167 1 1
TLR3 ATF3 0 0 283 303 1 2
TLR3 IFI35 0 0 260 289 1 1
TLR3 IFNL1 0 0 566 593 1 1
TLR3 IFI16 0 0 558 566 1 1
TLR3 MMP8 0 0 174 175 1 1
TLR3 IFNL2 0 0 518 548 1 1
TLR3 RAB7A 0 0 211 235 1 2
TLR3 CD9 0 0 194 211 1 1
TLR3 IL34 0 0 212 243 1 1
TLR3 NFKB2 0 0 386 429 1 1
TLR3 C8G 0 0 74 150 1 1
TLR3 TNFAIP3 0 0 392 405 1 2
TLR3 SPN 0 0 205 205 1 1
TLR3 ATP12A 0 0 134 168 1 1
TLR3 MAP3K14 0 0 90 221 1 1
TLR3 CD70 0 0 363 363 1 1
TLR3 IL1R2 0 0 181 181 1 1
TLR3 IL5 0 0 522 527 1 1
TLR3 TFRC 0 0 213 226 1 1
TLR3 FLT3LG 0 0 452 464 1 1
TLR3 HLA-E 0 0 216 233 1 1
TLR3 PPT2 0 0 0 156 1 1
TLR3 CD274 0 0 556 589 1 2
TLR3 PRPF19 0 0 0 234 1 1
TLR3 CBL 0 0 123 155 1 1
TLR3 DDX60 0 0 320 481 1 1
TLR3 GNLY 0 0 122 151 1 1
TLR3 LOX 0 0 173 173 1 2
TLR3 HMSD 0 0 0 164 1 1
TLR3 NTRK1 0 0 134 215 1 1
TLR3 KLRG1 0 0 204 216 1 1
TLR3 NLRP2 0 0 180 244 1 1
TLR3 MUC1 0 0 350 350 1 1
TLR3 AHR 0 0 209 209 1 2
TLR3 SERPINE1 0 0 180 179 1 1
TLR3 RPS6KB1 0 0 150 163 1 2
TLR3 USHBP1 0 0 0 167 1 1
TLR3 FCGR1A 0 0 359 376 1 1
TLR3 REM1 0 0 0 185 1 1
TLR3 HELZ2 0 0 83 192 1 1
TLR3 CCL1 0 0 231 230 1 1
TLR3 DUSP6 0 0 90 154 1 1
TLR3 CAT 0 0 209 248 1 2
TLR3 HGF 0 0 286 311 1 2
TLR3 SFTPD 0 0 216 245 1 1
TLR3 CWF19L2 0 0 0 174 1 1
TLR3 POU5F1 0 0 154 188 1 2
TLR3 SRRM3 0 0 0 197 1 1
TLR3 CANX 0 0 185 198 1 2
TLR3 PTPN2 0 0 96 198 1 2
TLR3 MLANA 0 0 193 193 1 1
TLR3 MYB 0 0 62 216 1 1
TLR3 IFI44 0 0 336 351 1 1
TLR3 HPRT1 0 0 324 327 1 1
TLR3 RNASEL 0 0 601 675 1 1
TLR3 RBM25 0 0 0 387 1 1
TLR3 CTLA4 0 0 556 556 1 2
TLR3 CD97 0 0 94 198 1 1
TLR3 CCL19 0 0 380 432 1 1
TLR3 CDKN1B 0 0 95 150 1 2
TLR3 CD2 0 0 193 193 1 1
TLR3 GPATCH8 0 0 0 190 1 1
TLR3 CDA 0 0 149 172 1 1
TLR3 IFIT1 0 0 633 668 1 1
TLR3 C1QB 0 0 128 296 1 1
TLR3 JPH1 0 0 66 190 1 1
TLR3 ADORA2B 0 0 171 171 1 1
TLR3 PF4 0 0 207 207 1 1
TLR3 ENSG00000244255 0 0 244 278 1 1
TLR3 F2R 0 0 150 185 1 1
TLR3 GHITM 0 0 234 234 1 1
TLR3 NTN1 0 0 66 188 1 1
TLR3 ANPEP 0 0 165 183 1 1
TLR3 MMP12 0 0 206 206 1 1
TLR3 NWD1 0 0 0 177 1 1
TLR3 PTPRQ 0 0 0 174 1 1
TLR3 EIF2S1 0 0 283 282 1 2
TLR3 JAK1 0 0 466 492 1 2
TLR3 NFATC2 0 0 127 154 1 1
TLR3 CDHR3 0 0 167 180 1 1
TLR3 SF3B1 0 0 0 238 1 1
TLR3 CD82 0 0 128 215 1 1
TLR3 TICAM2 213 0 518 824 1 1
TLR3 NCR2 0 0 248 248 1 1
TLR3 PPBP 0 0 146 298 1 1
TLR3 MOV10L1 0 0 0 159 1 1
TLR3 AP1S3 0 0 166 165 1 1
TLR3 IL32 0 0 267 267 1 1
TLR3 HMOX1 0 0 294 294 1 2
TLR3 TRIM14 0 0 156 155 1 1
TLR3 HFM1 0 0 0 185 1 1
TLR3 STAT6 0 0 392 420 1 1
TLR3 WWP2 0 0 143 181 1 1
TLR3 EIF2AK3 0 0 235 262 1 2
TLR3 A2M 0 0 108 150 1 1
TLR3 STK25 0 0 45 186 1 1
TLR3 CADM1 0 0 290 295 1 1
TLR3 ADAM22 0 0 167 167 1 1
TLR3 FLT1 0 0 397 427 1 1
TLR3 TNFRSF18 0 0 234 234 1 1
TLR3 ROBO2 0 0 0 175 1 1
TLR3 SUOX 0 0 0 261 1 1
TLR3 LGALS3 0 0 261 334 1 2
TLR3 FRMPD2 0 0 0 157 1 1
TLR3 SRC 270 0 920 942 1 2
TLR3 HP 0 0 161 174 1 1
TLR3 SAMD9L 0 0 122 286 1 1
TLR3 GFM1 0 0 0 181 1 1
TLR3 KIF5B 0 0 0 166 1 1
TLR3 YWHAB 0 0 45 164 1 1
TLR3 IL36B 0 0 97 334 1 1
TLR3 IL26 0 0 231 230 1 1
TLR3 KDM6A 0 0 62 157 1 1
TLR3 EEA1 0 0 411 422 1 2
TLR3 CD47 0 0 295 322 1 2
TLR3 TAP1 0 0 113 166 1 1
TLR3 NLRP7 0 0 167 232 1 1
TLR3 ARG2 0 0 315 315 1 1
TLR3 ERBB2 0 0 432 468 1 2
TLR3 IRF3 0 600 905 960 1 2
TLR3 CR2 0 0 261 272 1 1
TLR3 TLR9 0 0 916 429 1 2
TLR3 NTN5 0 0 0 167 1 1
TLR3 CD1D 0 0 459 470 1 1
TLR3 CFP 0 0 138 211 1 1
TLR3 NR1I2 0 0 165 193 1 1
TLR3 PYCARD 0 0 392 392 1 2
TLR3 MAP3K1 0 0 195 310 1 1
TLR3 CXCL10 0 0 717 732 1 2
TLR3 USH2A 0 0 95 215 1 1
TLR3 MALT1 0 0 244 260 1 1
TLR3 PABPC4 0 0 0 191 1 1
TLR3 GSK3A 0 0 46 174 1 1
TLR3 IL24 0 0 167 167 1 2
TLR3 DHX35 0 0 0 234 1 1
TLR3 PRPF39 0 0 0 190 1 1
TLR3 SIGLEC6 297 0 108 369 1 1
TLR3 ZBTB46 0 0 263 320 1 1
TLR3 ID2 0 0 166 165 1 1
TLR3 LSM7 0 0 0 169 1 1
TLR3 TCERG1L 0 0 0 161 1 1
TLR3 NDUFB6 0 0 0 248 1 1
TLR3 IL11 0 0 243 244 1 1
TLR3 SERPINB6 0 0 0 208 1 1
TLR3 LPHN3 0 0 0 176 1 1
TLR3 XIAP 0 0 270 282 1 2
TLR3 IFNLR1 0 0 392 392 1 1
TLR3 CLEC4C 0 0 469 477 1 1
TLR3 CFH 0 0 353 381 1 1
TLR3 DISC1 0 0 134 220 1 1
TLR3 IKBKB 0 600 595 840 1 2
TLR3 ACE2 0 0 113 171 1 2
TLR3 ATF6 0 0 181 181 1 2
TLR3 KLF4 0 0 206 221 1 2
TLR3 PANX1 0 0 234 234 1 1
TLR3 SLC10A1 0 0 112 167 1 1
TLR3 MRPL33 0 0 0 167 1 1
TLR3 CD4 0 0 765 777 1 2
TLR3 SEMA7A 0 0 84 153 1 1
TLR3 CARD8 0 0 123 173 1 1
TLR3 CARD14 0 0 123 185 1 1
TLR3 LY96 0 0 686 712 1 1
TLR3 IL12RB1 0 0 324 323 1 1
TLR3 IL17C 0 0 150 172 1 1
TLR3 TGFB2 0 0 202 215 1 1
TLR3 GBP2 0 0 270 312 1 1
TLR3 AKT1 0 0 469 540 1 2
TLR3 PPARG 0 0 325 348 1 2
TLR3 MYO16 0 0 0 161 1 1
TLR3 BECN1 0 0 323 376 1 2
TLR3 CAB39L 0 0 0 161 1 1
TLR3 ENSG00000262660 0 0 0 156 1 1
TLR3 ZC3HAV1 0 0 204 238 1 1
TLR3 THBS1 0 0 164 177 1 1
TLR3 ABCB1 0 0 90 150 1 2
TLR3 OLR1 0 0 282 293 1 2
TLR3 ANXA1 0 0 202 202 1 1
TLR3 ITGA2 0 0 156 204 1 1
TLR3 IL2 0 0 604 604 1 1
TLR3 TLR6 0 0 828 426 1 1
TLR3 LRP1 0 0 260 287 1 1
TLR3 CCDC130 0 0 0 180 1 1
TLR3 ISY1-RAB43 0 0 0 189 1 1
TLR3 DUSP1 0 0 294 344 1 1
TLR3 MAPK11 0 0 91 168 1 1
TLR3 RBM22 0 0 0 213 1 1
TLR3 PIAS1 0 0 123 158 1 1
TLR3 HSH2D 0 0 158 157 1 1
TLR3 PTGER3 0 0 221 221 1 1
TLR3 SSB 0 0 167 235 1 1
TLR3 IL18R1 0 0 208 208 1 1
TLR3 IFNA13 0 0 261 261 1 1
TLR3 CD81 0 0 310 325 1 1
TLR3 CARD11 0 0 156 216 1 1
TLR3 IFNA17 0 0 431 431 1 1
TLR3 HLA-DRA 312 0 134 408 1 1
TLR3 FASLG 0 0 430 430 1 1
TLR3 KDM6B 0 0 97 189 1 1
TLR3 SOCS3 0 0 466 494 1 1
TLR3 SLU7 0 0 0 163 1 1
TLR3 IL31 0 0 145 163 1 1
TLR3 STAT5A 0 0 282 321 1 1
TLR3 VTCN1 0 0 181 290 1 1
TLR3 IFNL3 0 0 519 549 1 1
TLR3 XAF1 0 0 174 173 1 1
TLR3 TNIP1 0 0 218 218 1 1
TLR3 RPS11 0 0 55 150 1 1
TLR3 SNRPB 0 0 0 154 1 1
TLR3 EMR3 0 0 0 151 1 1
TLR3 HNRNPC 0 0 77 175 1 1
TLR3 SNRNP200 0 0 0 185 1 1
TLR3 KRAS 0 0 158 263 1 2
TLR3 ITGB2 0 0 184 214 1 1
TLR3 LILRB4 0 0 190 190 1 1
TLR3 HLA-B 0 0 194 212 1 1
TLR3 CD3E 0 0 166 186 1 1
TLR3 GUSB 0 0 187 187 1 1
TLR3 RPS27A 0 900 60 908 1 1
TLR3 CXCL16 0 0 234 234 1 1
TLR3 PPP6C 0 0 55 194 1 1
TLR3 CDKN2A 0 0 212 237 1 2
TLR3 S100B 0 0 202 202 1 1
TLR3 MRC1 0 0 424 445 1 1
TLR3 GSK3B 0 0 122 297 1 2
TLR3 PFN1 0 0 49 194 1 1
TLR3 IL1RAP 0 0 234 250 1 1
TLR3 DUSP2 0 0 81 185 1 1
TLR3 PIGR 0 0 261 298 1 1
TLR3 MRPL27 0 0 0 180 1 1
TLR3 NOD2 0 0 682 710 1 2
TLR3 ECSIT 0 0 283 342 1 1
TLR3 CIITA 0 0 321 339 1 1
TLR3 KIDINS220 0 0 0 167 1 1
TLR3 ENSG00000258838 0 0 108 165 1 1
TLR3 IL13RA1 0 0 157 181 1 1
TLR3 PIK3CD 0 0 90 182 1 1
TLR3 ATG16L1 0 0 324 335 1 2
TLR3 CEBPB 0 0 366 366 1 2
TLR3 LTBR 0 0 255 271 1 1
TLR3 RIPK1 486 600 807 960 1 2
TLR3 UBE2V1 0 900 295 927 1 1
TLR3 APCS 0 0 122 176 1 1
TLR3 CARD16 0 0 0 171 1 1
TLR3 REL 0 0 426 526 1 2
TLR3 NLRP3 0 0 661 689 1 2
TLR3 MSR1 0 0 310 325 1 1
TLR3 MRPS16 0 0 0 167 1 1
TLR3 FCN2 0 0 162 175 1 1
TLR3 DHX29 0 0 48 154 1 1
TLR3 F3 0 0 246 270 1 1
TLR3 CASP3 0 0 459 475 1 2
TLR3 PTGS2 0 0 466 478 1 2
TLR3 TNFSF13B 0 0 506 516 1 1
TLR3 PPM1B 0 0 123 157 1 1
TLR3 ACE 0 0 150 184 1 1
TLR3 CTSS 0 0 167 235 1 1
TLR3 IL13 0 0 601 601 1 2
TLR3 TNFRSF10B 0 0 271 276 1 2
TLR3 RNASE2 0 0 171 171 1 1
TLR3 CYBB 0 0 507 527 1 2
TLR3 TRIM22 0 0 262 324 1 1
TLR3 MAL 0 0 123 152 1 1
TLR3 ASZ1 0 0 154 181 1 1
TLR3 ENSG00000268643 0 0 0 170 1 1
TLR3 MRPL45 0 0 0 208 1 1
TLR3 TNFRSF9 0 0 323 330 1 1
TLR3 DOCK8 0 0 167 211 1 1
TLR3 IL21R 0 0 141 199 1 1
TLR3 CLEC4E 0 0 510 517 1 1
TLR3 RORC 0 0 164 163 1 1
TLR3 FCGR2A 0 0 666 666 1 1
TLR3 CD79A 0 0 160 159 1 1
TLR3 KIT 0 0 243 297 1 2
TLR3 NTRK3 0 0 0 170 1 1
TLR3 GAPDHS 0 0 0 246 1 1
TLR3 NFATC1 0 0 170 186 1 2
TLR3 PDCD1LG2 0 0 378 412 1 1
TLR3 CD200 0 0 263 295 1 1
TLR3 PVRL1 0 0 134 170 1 1
TLR3 BST2 0 0 460 471 1 1
TLR3 FPR1 0 0 283 282 1 1
TLR3 IFNA21 0 0 451 451 1 1
TLR3 NLRP6 0 0 336 336 1 1
TLR3 PLP2 0 0 170 202 1 1
TLR3 PSMB10 0 0 155 185 1 1
TLR3 HBB 0 0 151 150 1 1
TLR3 IL10 0 0 736 789 1 2
TLR3 PFN2 0 0 0 189 1 1
TLR3 IRAK4 0 0 710 855 1 1
TLR3 FLT3 0 0 335 373 1 2
TLR3 OTUD5 0 0 310 325 1 1
TLR3 NR1H4 0 0 128 158 1 1
TLR3 DLG4 0 0 102 166 1 2
TLR3 TRIM26 0 0 128 206 1 1
TLR3 CWC25 0 0 0 194 1 1
TLR3 HLA-A 0 0 234 251 1 1
TLR3 LITAF 0 0 175 242 1 1
TLR3 FCGR3B 0 0 468 476 1 1
TLR3 CCL22 0 0 391 390 1 1
TLR3 ENG 0 0 223 251 1 2
TLR3 CTSG 0 0 231 243 1 1
TLR3 CCL3 0 0 602 617 1 1
TLR3 MARCO 0 0 244 262 1 1
TLR3 TRIM32 0 0 162 203 1 1
TLR3 GAD2 0 0 94 156 1 1
TLR3 IL18RAP 0 0 141 165 1 1
TLR3 RAG2 0 0 215 215 1 1
TLR3 CCR9 0 0 245 244 1 1
TLR3 FN1 0 0 427 434 1 2
TLR3 C3 0 0 369 412 1 2
TLR3 HNRNPDL 0 0 67 166 1 1
TLR3 MMP13 0 0 234 234 1 2
TLR3 PRKCA 0 0 171 171 1 1
TLR3 ELANE 0 0 284 295 1 1
TLR3 PLK3 0 0 62 184 1 1
TLR3 RIPK4 0 0 73 180 1 1
TLR3 MAP1LC3B 0 0 164 175 1 2
TLR3 XCL1 0 0 264 280 1 1
TLR3 CD1E 0 0 335 349 1 1
TLR3 SERPINB5 0 0 47 313 1 1
TLR3 UBC 0 900 108 912 1 2
TLR3 HAND2 0 0 0 248 1 1
TLR3 TSG101 0 0 160 159 1 2
TLR3 TXNL4B 0 0 0 171 1 1
TLR3 GBP3 0 0 167 245 1 1
TLR3 OBBP2 297 0 107 381 1 1
TLR3 TERT 0 0 155 154 1 2
TLR3 VAV1 0 0 152 151 1 1
TLR3 RPL23 0 0 0 158 1 1
TLR3 CXCR3 0 0 459 459 1 1
TLR3 RPL27A 0 0 0 165 1 1
TLR3 ATP4A 0 0 134 168 1 1
TLR3 IRF1 0 0 631 677 1 2
TLR3 TTF1 0 0 0 171 1 1
TLR3 C1QA 0 0 90 172 1 1
TLR3 SAMD9 0 0 67 213 1 1
TLR3 MYBL2 0 0 0 178 1 1
TLR3 ELN 0 0 193 193 1 1
TLR3 PPT1 0 0 0 156 1 1
TLR3 CALCOCO2 0 0 241 257 1 2
TLR3 TRPA1 0 0 169 192 1 1
TLR3 PDCD1 0 0 335 335 1 2
TLR3 P2RY2 0 0 167 167 1 1
TLR3 SMAD7 0 0 451 461 1 1
TLR3 OPTN 0 0 240 239 1 2
TLR3 NCL 0 0 149 230 1 2
TLR3 IFNB1 0 0 952 952 1 1
TLR3 ESR1 0 0 183 211 1 2
TLR3 UBE2D2 0 900 67 905 1 1
TLR3 SIKE1 0 0 529 529 1 1
TLR3 EOMES 0 0 139 152 1 1
TLR3 IL10RB 0 0 341 360 1 1
TLR3 AIRE 0 0 233 246 1 1
TLR3 MX1 0 0 662 823 1 1
TLR3 LSM5 0 0 0 160 1 1
TLR3 TAB1 0 600 421 795 1 1
TLR3 GNAT3 0 0 42 164 1 1
TLR3 TRAF2 0 0 270 284 1 2
TLR3 PPP3CB 0 0 0 182 1 1
TLR3 DHX33 0 0 276 357 1 1
TLR3 IL27RA 0 0 167 167 1 1
TLR3 CHST1 0 0 0 189 1 1
TLR3 PIK3CA 0 0 65 160 1 2
TLR3 CDC40 0 0 0 185 1 1
TLR3 SIGLEC11 297 0 0 338 1 1
TLR3 CWC22 0 0 0 197 1 1
TLR3 IL1R1 0 0 710 715 1 1
TLR3 PPIG 0 0 81 192 1 1
TLR3 MYC 0 0 341 346 1 2
TLR3 IRGM 270 0 266 454 1 2
TLR3 S100A7 0 0 158 157 1 1
TLR3 IFITM3 0 0 424 471 1 1
TLR3 IL18 0 0 681 705 1 2
TLR3 TRAPPC9 0 0 0 252 1 1
TLR3 TAB2 270 600 513 867 1 2
TLR3 SDHC 0 0 245 244 1 1
TLR3 AZI2 0 0 324 338 1 1
TLR3 IGF1R 0 0 94 154 1 2
TLR3 TREM1 0 0 518 518 1 1
TLR3 UBE2D1 0 900 70 905 1 1
TLR3 PI3 0 0 208 208 1 2
TLR3 SNRPE 0 0 0 154 1 2
TLR3 PGAM5 0 0 202 202 1 1
TLR3 NFE2L2 0 0 151 150 1 2
TLR3 TLR1 0 0 870 445 1 1
TLR3 CAB39 0 0 0 161 1 1
TLR3 NLRP10 0 0 157 156 1 1
TLR3 AKT2 0 0 87 207 1 2
TLR3 VWCE 0 0 0 165 1 1
TLR3 ENSG00000272772 0 0 0 209 1 1
TLR3 CD80 0 0 661 676 1 2
TLR3 NLRP12 0 0 283 282 1 1
TLR3 RBCK1 270 0 248 427 1 1
TLR3 FURIN 0 0 233 266 1 1
TLR3 DSP 0 0 70 167 1 1
TLR3 C5 0 0 108 171 1 1
TLR3 DHX58 0 0 681 798 1 1
TLR3 OSM 0 0 164 163 1 1
TLR3 UNK 0 0 167 202 1 1
TLR3 CH25H 0 0 231 247 1 1
TLR3 F2RL1 0 0 81 282 1 1
TLR3 PPIF 0 0 327 392 1 1
TLR3 MAP2K1 0 0 218 247 1 1
TLR3 PPP3CC 0 0 0 182 1 1
TLR3 TNFRSF13B 0 0 289 288 1 1
TLR3 NELFCD 0 0 336 336 1 1
TLR3 FXN 0 0 0 167 1 1
TLR3 TAX1BP1 0 0 193 193 1 2
TLR3 UBD 0 0 140 193 1 1
TLR3 RPS16 0 0 0 163 1 1
TLR3 CSF3 0 0 459 459 1 1
TLR3 MUC5B 0 0 235 328 1 1
TLR3 LMNA 0 0 209 209 1 2
TLR3 TRAF1 0 0 421 445 1 1
TLR3 MOB3B 0 0 0 154 1 1
TLR3 CAMP 0 0 653 653 1 2
TLR3 NRXN3 0 0 0 153 1 1
TLR3 SELPLG 0 0 170 169 1 1
TLR3 DDIT3 0 0 151 182 1 2
TLR3 PABPC1 0 0 69 241 1 1
TLR3 ARF5 0 0 0 163 1 1
TLR3 LCP2 0 0 119 154 1 1
TLR3 SPECC1 0 0 181 233 1 1
TLR3 KLRC1 0 0 287 286 1 1
TLR3 IRF9 0 0 601 612 1 1
TLR3 S100A1 0 0 150 185 1 1
TLR3 CFTR 0 0 181 181 1 2
TLR3 TRIM24 0 0 116 163 1 1
TLR3 FADD 270 600 586 870 1 2
TLR3 SARM1 0 600 602 881 1 1
TLR3 ADORA3 0 0 185 185 1 1
TLR3 MYD88 270 900 979 998 1 2
TLR3 ERN1 0 0 210 265 1 2
TLR3 TRIM23 0 0 211 356 1 1
TLR3 GATA3 0 0 296 313 1 1
TLR3 MSRB3 0 0 0 151 1 1
TLR3 CCL25 0 0 161 161 1 1
TLR3 CD55 0 0 244 243 1 1
TLR3 AGO2 0 0 231 244 1 2
TLR3 STAT3 0 0 598 613 1 2
TLR3 SKIV2L 0 0 180 179 1 1
TLR3 HMCN1 0 0 306 343 1 1
TLR3 HLA-DQB1 0 0 94 169 1 1
TLR3 CCL26 0 0 181 181 1 1
TLR3 SRSF1 0 0 57 163 1 1
TLR3 FGR 0 0 106 150 1 1
TLR3 LY86 0 0 234 374 1 1
TLR3 SNRPD1 0 0 43 156 1 2
TLR3 DAW1 0 0 0 157 1 1
TLR3 MAP1LC3A 0 0 134 220 1 2
TLR3 FCGR3A 0 0 468 476 1 1
TLR3 SOCS7 0 0 217 229 1 1
TLR3 EPHA2 0 0 122 196 1 1
TLR3 CXCR2 0 0 367 367 1 1
TLR3 MYOM2 0 0 254 254 1 1
TLR3 DDX18 0 0 0 195 1 1
TLR3 TNFRSF1B 0 0 281 313 1 1
TLR3 HERC5 0 0 203 254 1 1
TLR3 B7RP1 0 0 283 293 1 1
TLR3 TRAF5 0 0 325 338 1 1
TLR3 CYP27B1 0 0 171 171 1 1
TLR3 OAS1 0 0 562 581 1 1
TLR3 EDN1 0 0 229 228 1 1
TLR3 HIF1A 0 0 321 346 1 2
TLR3 MFAP1 0 0 0 177 1 1
TLR3 IL1B 0 0 778 821 1 2
TLR3 KIAA1429 270 0 0 270 1 1
TLR3 NCR3 0 0 279 279 1 1
TLR3 NCR1 0 0 338 338 1 1
TLR3 IL3RA 0 0 414 414 1 1
TLR3 MPO 0 0 325 329 1 2
TLR3 LYZ 0 0 156 187 1 1
TLR3 IL6 0 0 803 833 1 2
TLR3 F11R 0 0 165 165 1 1
TLR3 WDR34 0 0 398 398 1 1
TLR3 LMLN 0 0 183 189 1 1
TLR3 TNFRSF1A 0 0 640 651 1 1
TLR3 LSM4 0 0 0 167 1 1
TLR3 TRAF4 0 0 253 267 1 1
TLR3 HLA-G 0 0 275 291 1 1
TLR3 CTAG1A 0 0 335 335 1 1
TLR3 ENTPD1 0 0 213 230 1 1
TLR3 MAST1 0 0 0 180 1 1
TLR3 NOTCH1 0 0 254 271 1 2
TLR3 CD40LG 0 0 560 572 1 1
TLR3 PTGS1 0 0 134 152 1 1
TLR3 SEC61A1 0 0 143 156 1 1
TLR3 NLRP1 0 0 459 459 1 1
TLR3 APOBEC3G 0 0 373 373 1 1
TLR3 POTEF 0 0 203 315 1 1
TLR3 DDX21 0 0 331 378 1 1
TLR3 C4A 0 0 209 263 1 1
TLR3 SAA1 0 0 155 214 1 1
TLR3 CCNB1 0 0 92 182 1 1
TLR3 ANXA5 0 0 391 404 1 2
TLR3 LGALS9 0 0 264 280 1 1
TLR3 HSPD1 0 0 339 377 1 1
TLR3 CLEC4D 0 0 165 178 1 1
TLR3 RANBP2 0 0 60 207 1 1
TLR3 TNFSF18 0 0 183 183 1 1
TLR3 PLK1 0 0 134 246 1 2
TLR3 TNFSF9 0 0 254 254 1 1
TLR3 EPO 0 0 155 154 1 2
TLR3 CXCL13 0 0 324 323 1 1
TLR3 TECTA 0 0 0 157 1 1
TLR3 HAVCR1 0 0 103 274 1 1
TLR3 ARF1 0 0 0 199 1 1
TLR3 NTN3 0 0 0 167 1 1
TLR3 ARL3 0 0 0 260 1 1
TLR3 BIRC2 270 900 343 949 1 1
TLR3 IFNG 0 0 553 832 1 2
TLR3 CCL5 0 0 688 711 1 2
TLR3 TGFB3 0 0 156 170 1 1
TLR3 TNFRSF17 0 0 155 162 1 1
TLR3 PLCG2 0 0 207 220 1 1
TLR3 TLR4 0 0 911 427 1 2
TLR3 PABPC3 0 0 0 218 1 1
TLR3 EMR1 0 0 0 313 1 1
TLR3 SMAD2 0 0 184 198 1 2
TLR3 EPC2 0 0 223 234 1 1
TLR3 IL9R 0 0 67 150 1 1
TLR3 TOPORS 0 0 0 252 1 1
TLR3 TNFRSF25 0 0 214 214 1 1
TLR3 SNW1 0 0 0 248 1 1
TLR3 POTEE 0 0 0 176 1 1
TLR3 CD14 213 0 162 518 1 1
TLR3 PGLYRP2 0 0 113 153 1 1
TLR3 APOA1 0 0 159 158 1 1
TLR3 SNRPG 0 0 0 232 1 1
TLR3 NOS2 0 0 391 441 1 2
TLR3 KITLG 0 0 210 210 1 1
TLR3 SF3B5 0 0 0 179 1 1
TLR3 ENSG00000250349 0 0 193 193 1 1
TLR3 CLEC7A 0 0 603 617 1 1
TLR3 LONRF2 0 0 0 162 1 1
TLR3 TAB3 0 600 405 755 1 1
TLR3 C1R 0 0 134 194 1 1
TLR3 HMGB2 0 0 398 409 1 1
TLR3 BCL2L1 0 0 310 309 1 2
TLR3 NTNG2 0 0 0 167 1 1
TLR3 AOC3 0 0 297 297 1 1
TLR3 CCL4L1 0 0 456 487 1 1
TLR3 CXCL6 0 0 218 522 1 1
TLR3 SNCA 0 0 362 372 1 2
TLR3 CD27 0 0 398 398 1 1
TLR3 CD74 0 0 210 258 1 1
TLR3 CCR3 0 0 264 280 1 1
TLR3 CASP1 0 0 652 699 1 2
TLR3 HSPA1A 0 0 234 312 1 1
TLR3 TNFSF10 0 0 459 471 1 2
TLR3 CAV1 0 0 145 171 1 2
TLR3 ZFP36 0 0 166 181 1 1
TLR3 MST4 0 0 48 188 1 1
TLR3 GBP4 0 0 150 227 1 1
TLR3 HLA-DRB1 0 0 161 186 1 1
TLR3 PLK5 0 0 0 165 1 1
TLR3 MAP2K3 0 0 240 265 1 1
TLR3 FFAR2 0 0 167 167 1 1
TLR3 ARL17B 0 0 0 199 1 1
TLR3 IL10RA 0 0 324 338 1 1
TLR3 HNRNPA1 0 0 61 160 1 1
TLR3 BCL2L11 0 0 208 208 1 2
TLR3 SERPINA1 0 0 161 161 1 2
TLR3 LUC7L 0 0 0 183 1 1
TLR3 SIGLEC1 0 0 305 342 1 1
TLR3 CCL24 0 0 206 223 1 1
TLR3 AURKC 0 0 0 155 1 1
TLR3 PLCG1 0 0 95 207 1 1
TLR3 TNIP3 0 0 140 151 1 1
TLR3 TMEM173 0 0 505 521 1 1
TLR3 TICAM1 766 900 988 999 1 2
TLR3 PELI3 0 0 166 223 1 1
TLR3 PVRL2 0 0 112 164 1 1
TLR3 PRPF40A 0 0 0 161 1 1
TLR3 LAMP2 0 0 181 198 1 2
TLR3 CCRL2 0 0 335 349 1 1
TLR3 IL17RA 0 0 298 317 1 1
TLR3 LCK 0 0 182 280 1 1
TLR3 SNAPC4 0 0 0 171 1 1
TLR3 RPL4 0 0 0 163 1 1
TLR3 YWHAE 0 0 90 203 1 1
TLR3 CD69 0 0 468 476 1 1
TLR3 CCR5 0 0 505 515 1 1
TLR3 IL37 0 0 181 324 1 1
TLR3 RTP4 0 0 147 218 1 1
TLR3 PHF5A 0 0 0 174 1 1
TLR3 P2RY12 0 0 155 173 1 1
TLR3 LAMP3 0 0 180 179 1 1
TLR3 ATAD2 0 0 0 245 1 1
TLR3 PRDX1 0 0 116 176 1 1
TLR3 MEX3B 0 0 389 389 1 1
TLR3 HAVCR2 0 0 370 383 1 1
TLR3 PSMB8 0 0 223 240 1 1
TLR3 CALR 0 0 342 367 1 1
TLR3 SIGLEC7 297 0 108 375 1 1
TLR3 WDFY1 270 0 842 892 1 1
TLR3 CD8A 0 0 719 725 1 1
TLR3 RIPK2 0 0 429 457 1 2
TLR3 IL1RAPL2 0 0 95 232 1 1
TLR3 IL22RA2 0 0 166 165 1 1
TLR3 TNFSF4 0 0 391 390 1 1
TLR3 SLAMF1 0 0 194 194 1 1
TLR3 MMP2 0 0 243 242 1 2
TLR3 HSPA8 0 0 447 486 1 2
TLR3 RHOA 0 0 170 242 1 2
TLR3 EPCAM 0 0 205 222 1 2
TLR3 TNFRSF14 0 0 211 228 1 1
TLR3 IL36A 0 0 96 334 1 1
TLR3 UBE2N 0 900 317 930 1 1
TLR3 CXCL12 0 0 405 405 1 2
TLR3 TLR5 0 0 870 386 1 1
TLR3 PLA2G1B 0 0 171 171 1 1
TLR3 KLRK1 0 0 452 481 1 1
TLR3 LRRC59 0 0 129 200 1 1
TLR3 SART1 0 0 0 177 1 1
TLR3 NLRP9 0 0 96 158 1 1
TLR3 MLKL 0 0 507 542 1 2
TLR3 ADORA2A 0 0 217 217 1 1
TLR3 ZMAT2 0 0 0 173 1 1
TLR3 PTPRN 0 0 73 178 1 1
TLR3 UNC93B1 486 600 966 992 1 1
TLR3 RFTN1 0 0 244 243 1 1
TLR3 OCA2 0 0 161 161 1 1
TLR3 IL22 0 0 291 298 1 1
TLR3 CTAG1B 0 0 339 339 1 1
TLR3 CD24 0 0 216 216 1 2
TLR3 LARGE 0 0 0 189 1 1
TLR3 IL3 0 0 334 334 1 1
TLR3 ACTN3 0 0 0 212 1 1
TLR3 PRPF40B 0 0 0 273 1 1
TLR3 CEBPA 0 0 170 169 1 1
TLR3 LSM6 0 0 0 154 1 1
TLR3 FPR2 0 0 272 272 1 1
TLR3 DNMT1 0 0 151 156 1 2
TLR3 CD40 0 0 834 844 1 2
TLR3 ACTB 0 0 564 625 1 2
TLR3 CLDN5 0 0 145 163 1 1
TLR3 GAS6 0 0 217 234 1 1
TLR3 INS 0 0 371 371 1 2
TLR3 ENSG00000258555 0 0 172 171 1 1
TLR3 RNF5 0 0 139 152 1 1
TLR3 GLI3 0 0 162 178 1 1
TLR3 FCGR2B 0 0 457 457 1 1
TLR3 B2M 0 0 325 361 1 1
TLR3 PAX5 0 0 125 499 1 1
TLR3 TROVE2 0 0 216 216 1 1
TLR3 IL9 0 0 370 370 1 1
TLR3 ENSG00000272822 0 0 0 199 1 1
TLR3 ROBO3 0 0 294 422 1 1
TLR3 TNFRSF10A 0 0 294 299 1 1
TLR3 PPEF1 0 0 0 182 1 1
TLR3 SERPINB1 0 0 0 232 1 1
TLR3 MLLT4 0 0 150 183 1 1
TLR3 ARL17A 0 0 0 199 1 1
TLR3 IFI44L 0 0 242 274 1 1
TLR3 CD276 0 0 519 526 1 1
TLR3 IFNE 0 0 113 168 1 1
TLR3 KNG1 0 0 150 168 1 1
TLR3 LRRFIP1 0 0 304 347 1 1
TLR3 CASP8 270 600 959 987 1 2
TLR3 ITGB1 0 0 181 206 1 1
TLR3 PLEKHH2 0 0 46 196 1 1
TLR3 DPP4 0 0 159 177 1 1
TLR3 RNF31 270 0 256 433 1 1
TLR3 IL1A 0 0 602 610 1 1
TLR3 RHOB 0 0 81 161 1 1
TLR3 CCL4 0 0 558 583 1 1
TLR3 MAVS 0 0 762 843 1 2
TLR3 CUL5 0 0 95 157 1 1
TLR3 ABCA1 0 0 270 297 1 2
TLR3 YWHAG 0 0 0 161 1 1
TLR3 DDX58 0 0 870 930 1 1
TLR3 AIM2 0 0 606 608 1 2
TLR3 C4B 0 0 215 269 1 1
TLR3 TRIM21 0 0 400 437 1 1
TLR3 PLG 0 0 208 220 1 1
TLR3 DEFB4B 0 0 323 323 1 1
TLR3 DDX55 0 0 0 197 1 1
TLR3 MFGE8 0 0 166 165 1 1
TLR3 IGHV4-38-2 0 0 181 181 1 1
TLR3 ADIPOQ 0 0 147 165 1 2
TLR3 MOB1A 0 0 0 154 1 1
TLR3 MAGEA3 0 0 234 234 1 2
TLR3 AURKB 0 0 0 155 1 1
TLR3 ARG1 0 0 392 392 1 2
TLR3 CD79B 0 0 136 169 1 1
TLR3 HLA-DQA1 0 0 260 276 1 1
TLR3 C5AR2 0 0 163 163 1 1
TLR3 OTUB1 0 0 136 150 1 1
TLR3 STOX2 0 0 46 151 1 1
TLR3 HIST2H3PS2 0 0 216 229 1 1
TLR3 IFIH1 0 0 870 947 1 1
TLR3 FLG 0 0 211 239 1 1
TLR3 CSK 213 0 777 826 1 1
TLR3 CTGF 0 0 170 169 1 1
TLR3 HNRNPA2B1 0 0 97 193 1 1
TLR3 KLRF1 0 0 122 155 1 1
TLR3 PTGER4 0 0 205 205 1 1
TLR3 CD244 0 0 160 161 1 1
TLR3 CISH 0 0 450 458 1 1
TLR3 PRF1 0 0 459 459 1 1
TLR3 IL2RG 0 0 193 214 1 1
TLR3 NR3C1 0 0 210 253 1 1
TLR3 MX2 0 0 414 693 1 1
TLR3 APOBEC3F 0 0 151 150 1 1
TLR3 PMEL 0 0 324 323 1 1
TLR3 XCR1 0 0 505 526 1 1
TLR3 LIF 0 0 206 206 1 2
TLR3 TYR 0 0 171 171 1 2
TLR3 IL12RB2 0 0 142 216 1 1
TLR3 SNRPD2 0 0 47 160 1 1
TLR3 PPIB 0 0 112 198 1 1
TLR3 CX3CR1 0 0 421 420 1 1
TLR3 TRIM5 0 0 325 352 1 1
TLR3 SNRPN 0 0 0 154 1 1
TLR3 POTEJ 0 0 0 176 1 1
TLR3 DBR1 0 0 170 169 1 1
TLR3 RPTOR 0 0 86 165 1 2
TLR3 MRPS5 0 0 0 185 1 1
TLR3 DEFB103B 0 0 391 390 1 1
TLR3 LUC7L2 0 0 0 183 1 1
TLR3 CASP9 0 0 259 290 1 2
TLR3 NANOG 0 0 155 187 1 2
TLR3 MAPK9 0 0 159 208 1 2
TLR3 TLR7 0 500 913 698 1 2
TLR3 NRP1 0 0 357 357 1 1
TLR3 PLK2 0 0 46 170 1 1
TLR3 NRXN2 0 0 0 153 1 1
TLR3 CD59 0 0 167 194 1 1
TLR3 IL17A 0 0 776 777 1 2
TLR3 DDX3X 0 0 302 347 1 1
TLR3 IL23R 0 0 241 240 1 1
TLR3 HERC6 0 0 134 233 1 1
TLR3 CD209 0 0 563 569 1 1
TLR3 CD300LF 0 0 154 153 1 1
TLR3 MMP7 0 0 150 188 1 1
TLR3 IFI30 0 0 141 178 1 1
TLR3 CASP2 0 0 142 167 1 1
TLR3 LUC7L3 0 0 0 183 1 1
TLR3 IL7 0 0 406 406 1 1
TLR3 BDNF 0 0 247 274 1 2
TLR3 CD44 0 0 391 390 1 2
TLR3 HLA-DMA 0 0 202 202 1 1
TLR3 HSPA2 0 0 0 169 1 1
TLR3 TIRAP 0 0 877 895 1 1
TLR3 TANK 0 600 603 838 1 2
TLR3 HNRNPD 0 0 93 189 1 1
TLR3 MOB1B 0 0 0 154 1 1
TLR3 BTK 0 0 487 513 1 1
TLR3 SOCS1 0 0 519 547 1 1
TLR3 RNF41 0 0 183 202 1 1
TLR3 IGF1 0 0 218 235 1 2
TLR3 MAPK1 0 0 208 227 1 2
TLR3 DEFB4A 0 0 500 499 1 1
TLR3 APOL1 0 0 136 157 1 2
TLR3 APOB 0 0 166 181 1 2
TLR3 CSF1R 0 0 369 414 1 1
TLR3 GBP5 0 0 183 212 1 1
TLR3 PRPF8 0 0 0 219 1 1
TLR3 ITPA 0 0 134 152 1 1
TLR3 RTN4IP1 0 0 122 160 1 1
TLR3 TNFSF14 0 0 142 160 1 1
TLR3 CXCL3 0 0 263 464 1 1
TLR3 FGF2 0 0 260 260 1 2
TLR3 RELB 0 0 416 416 1 2
TLR3 PPEF2 0 0 0 182 1 1
TLR3 POTEI 0 0 0 176 1 1
TLR3 CD63 0 0 218 218 1 2
TLR3 VWF 0 0 171 274 1 1
TLR3 IFNAR1 0 0 687 720 1 1
TLR3 TNFAIP6 0 0 261 272 1 1
TLR3 CISD3 0 0 0 167 1 1
TLR3 ENSG00000272980 0 0 325 325 1 1
TLR3 NOS3 0 0 150 165 1 2
TLR3 ACTA2 0 0 74 184 1 1
TLR3 RNF170 270 0 59 283 1 1
TLR3 CD36 0 0 62 159 1 2
TLR3 TIMD4 0 0 195 212 1 1
TLR3 CCND1 0 0 181 193 1 2
TLR3 LPHN2 0 0 0 176 1 1
TLR3 CD19 0 0 504 507 1 1
TLR3 ASCC3 0 0 0 185 1 1
TLR3 IFIT2 0 0 556 598 1 1
TLR3 SIGLEC10 297 0 125 396 1 1
TLR3 PTAFR 0 0 150 168 1 1
TLR3 NCF1 0 0 419 432 1 1
TLR3 IRAK2 270 0 661 770 1 1
TLR3 BLNK 0 0 155 207 1 1
TLR3 MGA 0 0 283 294 1 1
TLR3 RRAD 0 0 124 230 1 1
TLR3 CD207 0 0 469 488 1 1
TLR3 EIF4E 0 0 150 188 1 2
TLR3 HIST2H2BE 0 0 218 230 1 1
TLR3 SLPI 0 0 306 306 1 1
TLR3 PPP2CA 0 0 57 196 1 1
TLR3 CCDC94 0 0 0 180 1 1
TLR3 DMTF1 0 0 0 171 1 1
TLR3 YWHAQ 0 0 0 161 1 1
TLR3 UBB 0 900 0 906 1 1
TLR3 PECAM1 0 0 261 261 1 1
TLR3 MARCH1 0 0 126 171 1 1
TLR3 FSTL1 0 0 602 610 1 1
TLR3 RETNLB 0 0 188 188 1 1
TLR3 ENSG00000264813 0 0 143 165 1 1
TLR3 MOB3A 0 0 0 154 1 1
TLR3 LCP1 0 0 0 185 1 1
TLR3 TXN 0 0 158 181 1 1
TLR3 SIDT1 0 0 134 190 1 1
TLR3 CD38 0 0 263 263 1 2
TLR3 CD46 0 0 204 204 1 2
TLR3 IFRD1 0 0 138 191 1 1
TLR3 SLC16A8 0 0 0 256 1 1
TLR3 SNRPF 0 0 0 295 1 1
TLR3 SNRPC 0 0 0 177 1 1
TLR3 COLEC12 0 0 127 162 1 1
TLR3 LDLR 0 0 234 245 1 2
TLR3 PRKCD 0 0 180 188 1 2
TLR3 REG3A 0 0 113 150 1 1
TLR3 RIPK3 0 600 710 885 1 2
TLR3 PRPF3 0 0 0 163 1 1
TLR3 MRPS9 0 0 0 167 1 1
TLR3 RAB7B 0 0 231 275 1 1
TLR3 STAT5B 0 0 270 310 1 1
TLR3 TGFB1 0 0 193 285 1 2
TLR3 KDR 0 0 171 230 1 2
TLR3 IL4I1 0 0 108 151 1 1
TLR3 MARCH5 0 0 97 158 1 1
TLR3 PACSIN1 0 0 73 184 1 1
TLR3 KLRB1 0 0 184 243 1 1
TLR3 DDX39B 0 0 123 201 1 1
TLR3 PLRG1 0 0 0 229 1 1
TLR3 RAC2 0 0 144 218 1 1
TLR3 RAB11A 0 0 157 240 1 2
TLR3 CLEC5A 0 0 292 318 1 1
TLR3 TBK1 486 600 897 982 1 2
TLR3 CYP4V2 0 0 138 191 1 1
TLR3 YTHDC2 0 0 0 155 1 1
TLR3 PTPN6 0 0 111 218 1 1
TLR3 FOXP3 0 0 526 542 1 2
TLR3 MAP3K19 0 0 0 179 1 1
TLR3 RNASE7 0 0 170 176 1 1
TLR3 SERPINB3 0 0 45 307 1 1
TLR3 SERPINB7 0 0 0 309 1 1
TLR3 CCR8 0 0 181 181 1 1
TLR3 ALYREF 0 0 45 171 1 1
TLR3 CD180 0 0 320 153 1 1
TLR3 RSAD2 0 0 561 632 1 1
TLR3 PARP9 0 0 113 178 1 1
TLR3 IL19 0 0 178 179 1 1
TLR3 CDKN3 0 0 88 152 1 1
TLR3 MIF 0 0 261 261 1 2
TLR3 ATG3 0 0 161 161 1 2
TLR3 RAG1 0 0 266 266 1 1
TLR3 CDC42 0 0 157 230 1 2
TLR3 F2 0 0 103 177 1 1
TLR3 MRPL4 0 0 0 163 1 1
TLR3 ADA 0 0 248 248 1 1
TLR3 IRF8 0 0 508 538 1 1
TLR3 APOE 0 0 324 338 1 2
TLR3 BBOX1 0 0 161 174 1 1
TLR3 FOXO3 0 0 143 158 1 2
TLR3 TNFSF11 0 0 270 285 1 2
TLR3 RNPC3 0 0 0 219 1 1
TLR3 ISY1 0 0 0 189 1 1
TLR3 TH 0 0 113 204 1 2
TLR3 CD34 0 0 395 395 1 2
TLR3 NGF 0 0 234 261 1 2
TLR3 UBA7 0 0 134 185 1 1
TLR3 XAB2 0 0 0 211 1 1
TLR3 EIF4EBP1 0 0 112 169 1 2
TLR3 CYLD 0 0 394 394 1 1
TLR3 USP25 0 0 155 154 1 1
TLR3 PTPN23 0 0 0 154 1 1
TLR3 DDX56 0 0 358 398 1 1
TLR3 HSP90AB1 0 0 67 177 1 2
TLR3 AXL 0 0 325 374 1 2
TLR3 IFNGR2 0 0 278 278 1 1
TLR3 BCL6 0 0 235 266 1 1
TLR3 UBQLN1 0 0 368 408 1 1
TLR3 GJA1 0 0 154 153 1 1
TLR3 PPP3CA 0 0 0 182 1 1
TLR3 CD58 0 0 181 181 1 1
TLR3 GPT 0 0 263 275 1 1
TLR3 TRIM69 270 0 61 347 1 1
TLR3 ARF4 0 0 0 163 1 1
TLR3 DROSHA 0 0 201 225 1 1
TLR3 RNF216 192 0 398 492 1 1
TLR3 NOX4 0 0 154 169 1 2
TLR3 NLRC4 0 0 517 527 1 2
TLR3 CLDN1 0 0 142 161 1 1
TLR3 DUOX1 0 0 187 202 1 1
TLR3 VIP 0 0 172 171 1 1
TLR3 CD247 0 0 228 227 1 1
TLR3 AQR 0 0 0 167 1 1
TLR3 NTRK2 0 0 66 163 1 1
TLR3 INPP5D 0 0 218 230 1 1
TLR3 CCL14 0 0 123 157 1 1
TLR3 VCAM1 0 0 394 435 1 1
TLR3 IFIT3 0 0 413 505 1 1
TLR3 SNRPB2 0 0 0 219 1 1
TLR3 CIRBP 0 0 57 157 1 1
TLR3 FAS 0 0 333 387 1 2
TLR3 SUMO1 0 0 96 181 1 1
TLR3 CSF2 0 0 663 670 1 1
TLR3 ACKR1 0 0 213 213 1 1
TLR3 DDX10 0 0 0 258 1 1
TLR3 SF3A3 0 0 0 224 1 1
TLR3 STK38L 0 0 0 167 1 1
TLR3 CCL7 0 0 401 434 1 1
TLR3 SDC1 0 0 218 218 1 1
TLR3 PTGES 0 0 205 205 1 1
TLR3 SF3B3 0 0 74 270 1 1
TLR3 ARF6 0 0 75 156 1 1
TLR3 LILRA4 0 0 270 270 1 1
TLR3 RPL3L 0 0 0 165 1 1
TLR3 TLR2 0 0 962 449 1 2
TLR3 AUH 0 0 0 157 1 1
TLR3 PMAIP1 0 0 194 194 1 2
TLR3 IFITM5 0 0 166 242 1 1
TLR3 TOLLIP 157 0 470 542 1 1
TLR3 TRAF3 157 600 891 967 1 2
TLR3 MET 0 0 123 166 1 2
TLR3 CD86 0 0 681 693 1 1
TLR3 ENSG00000277117 0 0 284 294 1 1
TLR3 BGN 0 0 255 151 1 1
TLR3 TBKBP1 0 0 294 299 1 1
TLR3 PGLYRP3 0 0 125 218 1 1
TLR3 CFB 0 0 325 356 1 1
TLR3 PGF 0 0 306 306 1 1
TLR3 HNRNPAB 0 0 74 172 1 1
TLR3 SHARPIN 270 0 233 416 1 1
TLR3 NOD1 0 0 726 743 1 2
TLR3 YWHAZ 0 0 101 213 1 1
TLR3 CCL27 0 0 234 234 1 1
TLR3 FOS 0 0 342 361 1 2
TLR3 CLEC9A 0 0 562 581 1 1
TLR3 IL15RA 0 0 189 215 1 1
TLR3 DDX24 0 0 118 204 1 1
TLR3 IRG1 0 0 329 343 1 1
TLR3 DDX31 0 0 0 266 1 1
TLR3 IRAK3 0 0 520 582 1 1
TLR3 SIGIRR 0 0 452 463 1 1
TLR3 PTPN11 0 0 249 339 1 1
TLR3 NRAS 0 0 67 150 1 1
TLR3 GBP6 0 0 143 221 1 1
TLR3 HSPA5 0 0 177 235 1 2
TLR3 BTRC 0 0 163 163 1 1
TLR3 CCL8 0 0 341 366 1 1
TLR3 CCL17 0 0 366 366 1 1
TLR3 IFNGR1 0 0 391 404 1 1
TLR3 SOD2 0 0 150 166 1 2
TLR3 SFN 0 0 52 170 1 2
TLR3 CASP4 0 0 203 303 1 2
TLR3 PTPN12 0 0 74 179 1 1
TLR3 SOCS2 0 0 245 256 1 1
TLR3 SLC11A1 0 0 180 219 1 1
TLR3 ITGAX 0 0 661 680 1 1
TLR3 KLK11 0 0 158 171 1 1
TLR3 SAMHD1 0 0 346 361 1 1
TLR3 NLRP11 0 0 418 418 1 1
TLR3 SH2D1A 0 0 96 199 1 1
TLR3 S100A12 0 0 166 165 1 1
TLR3 CHUK 0 600 600 845 1 1
TLR3 CUL3 0 0 421 472 1 2
TLR3 STK24 0 0 0 182 1 1
TLR3 TSPO 0 0 123 161 1 1
TLR3 HCK 0 0 143 185 1 1
TLR3 HMGB3 0 0 538 538 1 1
TLR3 UBE2L6 0 0 124 173 1 1
TLR3 IFIT1B 0 0 106 193 1 1
TLR3 YWHAH 0 0 0 161 1 1
TLR3 CSF1 0 0 468 488 1 1
TLR3 DTX3L 0 0 71 156 1 1
TLR3 TRIM68 0 0 103 156 1 1
TLR3 PRDM1 0 0 210 210 1 1
TLR3 HDAC1 0 0 156 169 1 2
TLR3 MSRB1 0 0 0 151 1 1
TLR3 IL33 0 0 508 518 1 2
TLR3 CXCL1 0 0 556 677 1 2
TLR3 IL1RL1 0 0 321 336 1 1
TLR3 TNFRSF21 0 0 139 162 1 1
TLR3 PGLYRP1 0 0 254 254 1 1
TLR3 AFP 0 0 124 178 1 2
TLR3 LIPC 0 0 107 300 1 1
TLR3 CLEC4M 0 0 243 254 1 1
TLR3 AICDA 0 0 270 270 1 1
TLR3 PSMB9 0 0 240 258 1 1
TLR3 CCL11 0 0 391 414 1 1
TLR3 HEATR6 0 0 0 211 1 1
TLR3 ALOX5 0 0 167 167 1 1
TLR3 NOTCH2 0 0 150 188 1 1
TLR3 CD1B 0 0 349 363 1 1
TLR3 ATG12 0 0 247 246 1 2
TLR3 PRKCQ 0 0 126 154 1 2
TLR3 CD5 0 0 217 217 1 1
TLR3 CD28 0 0 459 470 1 1
TLR3 TRIM56 0 0 324 364 1 1
TLR3 IFNA5 0 0 284 328 1 1
TLR3 PPIA 0 0 194 272 1 1
TLR3 ISYNA1 0 0 347 347 1 1
TLR3 CXCL5 0 0 324 587 1 1
TLR3 MAPK14 0 0 324 416 1 2
TLR3 CD226 0 0 202 202 1 1
TLR3 CSF3R 0 0 112 150 1 1
TLR3 MAPK10 0 0 122 173 1 2
TLR3 MRPL21 0 0 0 167 1 1
TLR3 UBA52 0 900 0 900 1 1
TLR3 ATAD2B 0 0 0 239 1 1
TLR3 ZC3H12A 0 0 203 232 1 1
TLR3 LSM10 0 0 0 154 1 1
TLR3 TCF4 0 0 180 193 1 1
TLR3 MAP3K3 0 0 156 277 1 1
TLR3 NFKBIA 0 0 603 626 1 2
TLR3 S1PR1 0 0 167 196 1 1
TLR3 SYK 270 0 459 608 1 2
TLR3 LEP 0 0 171 171 1 1
TLR3 FCER1G 0 0 159 207 1 1
TLR3 TRAF7 0 0 194 213 1 1
TLR3 DNM1L 0 0 112 163 1 2
TLR3 CASP5 0 0 217 316 1 1
TLR3 VEGFA 0 0 469 469 1 2
TLR3 SNIP1 0 0 0 166 1 1
TLR3 LRR1 0 0 350 367 1 1
TLR3 IRF4 0 0 391 404 1 1
TLR3 MBP 0 0 202 214 1 2
TLR3 TREML4 0 0 181 181 1 1
TLR3 PTEN 0 0 234 288 1 2
TLR3 CCL20 0 0 510 510 1 1
TLR3 GFAP 0 0 264 282 1 2
TLR3 CXCR6 0 0 166 165 1 1
TLR3 CXCL2 0 0 467 612 1 1
TLR3 LPHN1 0 0 0 176 1 1
TLR3 PTK7 0 0 0 189 1 1
TLR3 ATG7 0 0 242 269 1 2
TLR3 TRAT1 0 0 404 417 1 1
TLR3 TAC1 0 0 157 156 1 1
TLR3 TGFBR2 0 0 108 152 1 1
TLR3 DHX8 0 0 0 382 1 1
TLR3 TJP1 0 0 267 268 1 1
TLR3 SELE 0 0 340 366 1 1
TLR3 CCL23 0 0 147 162 1 1
TLR3 SNRNP40 0 0 0 156 1 1
TLR3 ACTG1 0 0 194 308 1 1
TLR3 IKZF1 0 0 142 158 1 1
TLR3 CMPK2 0 0 150 285 1 1
TLR3 ICAM3 0 0 261 261 1 1
TLR3 RPS13 0 0 69 174 1 1
TLR3 NRXN1 0 0 0 153 1 1
TLR3 IL23A 0 0 410 410 1 1
TLR3 CTSD 0 0 141 172 1 2
TLR3 TYRO3 0 0 321 354 1 1
TLR3 ATM 0 0 163 169 1 2
TLR3 THBD 0 0 556 604 1 1
TLR3 IKBKG 270 600 599 874 1 1
TLR3 CCR7 0 0 503 508 1 1
TLR3 TIAL1 0 0 74 211 1 1
TLR3 AKT3 0 0 55 180 1 2
TLR3 CXCR5 0 0 275 366 1 1
TLR3 UNC5B 0 0 0 153 1 1
TLR3 STMN1 0 0 370 384 1 1
TLR3 NCAM1 0 0 374 385 1 1
TLR3 TBX21 0 0 391 400 1 1
TLR3 LY6E 0 0 161 161 1 1
TLR3 ISG15 0 0 614 684 1 2
TLR3 WDFY4 0 0 624 643 1 1
TLR3 ADAM17 0 0 218 231 1 1
TLR3 SUGT1 0 0 0 216 1 1
TLR3 SERPINB8 0 0 0 309 1 1
TLR3 NFKBIB 0 0 254 350 1 1
TLR3 SERPINB9 0 0 122 245 1 1
TLR3 SOCS6 0 0 194 206 1 1
TLR3 TGFBR1 0 0 116 178 1 1
TLR3 USP18 0 0 392 418 1 1
TLR3 IL22RA1 0 0 155 173 1 1
TLR3 MRPL17 0 0 0 167 1 1
TLR3 ENSG00000255819 0 0 451 480 1 1
TLR3 HSPB1 0 0 146 199 1 2
TLR3 CMA1 0 0 170 182 1 1
TLR3 FAM120B 0 0 193 211 1 1
TLR3 XBP1 0 0 265 265 1 2
TLR3 SCARF1 0 0 536 546 1 1
TLR3 STAT2 0 0 649 681 1 1
TLR3 HLA-C 0 0 209 227 1 1
TLR3 PTPN1 0 0 101 202 1 1
TLR3 MOB3C 0 0 0 154 1 1
TLR3 MT-ND1 0 0 0 248 1 1
TLR3 PPP5D1 0 0 0 182 1 1
TLR3 ATG5 0 0 327 331 1 2
TLR3 MAP2K6 270 0 181 397 1 1
TLR3 ERCC6 0 0 146 201 1 1
TLR3 SH2D3A 0 0 403 403 1 1
TLR3 TLR8 0 500 898 691 1 1
TLR3 TIA1 0 0 96 253 1 1
TLR3 GRIN1 0 0 52 154 1 1
TLR3 ITGAM 0 0 611 630 1 1
TLR3 GATA2 0 0 137 158 1 1
TLR3 ACKR2 0 0 294 294 1 1
TLR3 MAP3K5 0 0 180 220 1 1
TLR3 HMGB1 0 0 619 627 1 2
TLR3 DUOX2 0 0 146 162 1 1
TLR3 RAC1 0 0 113 190 1 2
TLR3 IRF5 0 0 606 677 1 1
TLR3 PPP1CA 0 0 180 301 1 1
TLR3 RCVRN 0 0 0 205 1 1
TLR3 CTSK 0 0 171 273 1 2
TLR3 LYN 0 0 294 344 1 1
TLR3 CTSB 0 0 293 293 1 2
TLR3 NOX1 0 0 156 189 1 1
TLR3 SPI1 0 0 324 340 1 1
TLR3 MCL1 0 0 181 181 1 2
TLR3 ERVW-1 0 0 294 294 1 1
TLR3 SIRT1 0 0 143 157 1 2
TLR3 ELF4 0 0 95 151 1 1
TLR3 MEFV 0 0 490 497 1 1
TLR3 EFTUD2 0 0 0 181 1 1
TLR3 SLC15A4 0 0 167 167 1 1
TLR3 ADORA1 0 0 181 181 1 1
TLR3 CEACAM5 0 0 416 416 1 1
TLR3 PROS1 0 0 143 191 1 1
TLR3 SF3A2 0 0 0 192 1 1
TLR3 IL2RA 0 0 229 261 1 1
TLR3 PPP5C 0 0 0 182 1 1
TLR3 ITGAE 0 0 520 534 1 1
TLR3 RNF125 0 0 291 290 1 1
TLR3 IL15 0 0 564 584 1 1
TLR3 LGMN 0 0 150 168 1 1
TLR3 IFNA1 0 0 833 833 1 1
TLR3 NR0B2 0 0 142 171 1 1
TLR3 ROBO4 0 0 0 163 1 1
TLR3 IL36G 0 0 142 368 1 1
TLR3 TCERG1 0 0 0 161 1 1
TLR3 PRB1 0 0 270 270 1 1
TLR3 ADAM10 0 0 181 194 1 1
TLR3 LILRB1 0 0 183 183 1 1
TLR3 CDC5L 0 0 0 171 1 1
TLR3 IFITM2 0 0 218 282 1 1
TLR3 CCL21 0 0 341 355 1 1
TLR3 AREG 0 0 193 193 1 1
TLR3 OASL 0 0 413 555 1 1
TLR3 TCF3 0 0 195 209 1 1
TLR3 MAP3K8 0 0 273 394 1 1
TLR3 FUT4 0 0 157 156 1 1
TLR3 OAS3 0 0 370 432 1 1
TLR3 MDC1 0 0 128 151 1 1
TLR3 CLEC4A 0 0 391 400 1 1
TLR3 PRSS57 0 0 262 273 1 1
TLR3 IL17RC 0 0 151 150 1 1
TLR3 IL12A 0 0 57 260 1 1
TLR3 CASP10 0 0 232 277 1 1
TLR3 LY75 0 0 560 593 1 1
TLR3 GOLPH3 0 0 179 179 1 1
TLR3 IL1RL2 0 0 193 193 1 1
TLR3 LAG3 0 0 292 292 1 1
TLR3 ACTA1 0 0 123 217 1 1
TLR3 SUCNR1 0 0 596 596 1 1
TLR3 IRAK1 0 900 730 979 1 1
TLR3 CARD9 0 0 391 390 1 1
TLR3 NLRP4 0 0 154 175 1 1
TLR3 MAP3K7 486 600 418 876 1 2
TLR3 NUP153 0 0 123 159 1 1
TLR3 ZBP1 0 0 460 509 1 1
TLR3 NFKBIZ 0 0 262 285 1 1
TLR3 CD200R1 0 0 251 250 1 1
TLR3 TP53 0 0 393 392 1 2
TLR3 LCN2 0 0 278 293 1 1
TLR3 MDM2 0 0 134 152 1 2
TLR3 TGM2 0 0 174 194 1 2
TLR3 TRIM16 0 0 123 478 1 2
TLR3 CWC15 0 0 49 226 1 1
TLR3 TSLP 0 0 556 556 1 1
TLR3 LAMP1 0 0 370 370 1 2
TLR3 CFLAR 0 0 392 424 1 2
TLR3 EGFR 0 0 388 427 1 2
TLR3 TNFRSF4 0 0 369 369 1 1
TLR3 PPP1CC 0 0 74 210 1 1
TLR3 DEFB103A 0 0 391 390 1 1
TLR3 MICA 0 0 283 298 1 1
TLR3 SFPQ 0 0 189 189 1 1
TLR3 PPP1R11 0 0 0 227 1 1
TLR3 KCND3 270 0 0 270 1 1
TLR3 TRIL 270 0 265 414 1 1
TLR3 MUC5AC 0 0 267 356 1 1
TLR3 EIF2AK4 0 0 150 168 1 2
TLR3 PTPN22 0 0 265 362 1 1
TLR3 HBEGF 0 0 233 232 1 1
TLR3 TRIM8 0 0 196 244 1 1
TLR3 IFNA2 0 0 467 500 1 1
TLR3 NLRC5 0 0 338 407 1 1
TLR3 JAK2 0 0 335 368 1 2
TLR3 APAF1 0 0 207 227 1 2
TLR3 BUD13 0 0 0 183 1 1
TLR3 PTX3 0 0 384 384 1 1
TLR3 MYBL1 0 0 0 185 1 1
TLR3 BRD4 0 0 134 166 1 2
TLR3 ARMS2 0 0 324 323 1 1
TLR3 HRAS 0 0 203 284 1 2
TLR3 PPP1R42 0 0 0 163 1 1
TLR3 CTNNB1 0 0 294 308 1 2
TLR3 IFNA4 0 0 314 313 1 1
TLR3 EGR1 0 0 216 231 1 2
TLR3 MFN2 0 0 95 182 1 2
TLR3 APP 0 0 206 235 1 2
TLR3 TRPV1 0 0 195 201 1 2
TLR3 MRPL12 0 0 0 156 1 1
TLR3 C3AR1 0 0 218 236 1 1
TLR3 PASK 0 0 0 152 1 1
TLR3 EFTUD1 0 0 0 181 1 1
TLR3 ERAP1 0 0 128 173 1 1
TLR3 IKBKE 0 600 519 889 1 1
TLR3 WDR25 0 0 0 185 1 1
TLR3 CNPY4 0 0 217 233 1 1
TLR3 TRIM27 0 0 195 224 1 1
TLR3 NR1H3 0 0 54 162 1 1
TLR3 RAB5A 0 0 189 240 1 2
TLR3 SUMO2 0 0 75 152 1 1
TLR3 MTNR1A 0 0 67 170 1 1
TLR3 CXCL8 0 0 733 784 1 2
TLR3 ENSG00000268500 0 0 107 155 1 1
TLR3 IL6R 0 0 265 265 1 1
TLR3 ARF3 0 0 52 208 1 1
TLR3 PAX2 0 0 0 347 1 1
TLR3 ZMAT5 0 0 0 177 1 1
TLR3 CTSL 0 0 243 242 1 2
TLR3 NFKBID 0 0 181 207 1 1
TLR3 PPP4C 0 0 0 182 1 1
TLR3 MAP3K2 0 0 46 183 1 1
TLR3 PIK3C3 0 0 161 174 1 2
TLR3 NLRC3 0 0 287 400 1 1
TLR3 MOG 0 0 246 245 1 1
TLR3 CTRL 0 0 181 193 1 2
TLR3 SNRPA 0 0 49 225 1 1
TLR3 GNA13 0 0 0 192 1 1
TLR3 SOCS5 0 0 233 244 1 1
TLR3 SRRM2 0 0 0 197 1 1
TLR3 STAT1 0 0 681 772 1 2
TLR3 UNC5C 0 0 0 181 1 1
TLR3 DEFB1 0 0 335 335 1 1
TLR3 GZMB 0 0 437 445 1 1
TLR3 OCLN 0 0 310 309 1 1
TLR3 CXCR4 0 0 424 424 1 2
TLR3 LSM3 0 0 0 182 1 1
TLR3 RNF138 0 0 53 457 1 1
TLR3 MMP1 0 0 202 202 1 1
TLR3 PABPC1L 0 0 0 172 1 1
TLR3 MTOR 0 0 266 277 1 2
TLR3 ADAR 0 0 344 364 1 1
TLR3 CD163 0 0 391 390 1 1
TLR3 NKTR 0 0 46 161 1 1
TLR3 RBMX2 0 0 0 197 1 1
TLR3 ATP13A1 0 0 0 221 1 1
TLR3 PRPF4 0 0 0 157 1 1
TLR3 IL4R 0 0 253 269 1 1
TLR3 IL1RAPL1 0 0 95 176 1 1
TLR3 C5AR1 0 0 282 299 1 1
TLR3 CCL13 0 0 167 167 1 1
TLR3 FRAS1 0 0 0 154 1 1
TLR3 UBE2D3 0 900 61 904 1 1
TLR3 PPID 0 0 45 227 1 1
TLR3 MOV10 0 0 62 188 1 1
TLR3 CREBBP 0 0 184 230 1 1
TLR3 IL2RB 0 0 167 192 1 1
TLR3 HLA-DQA2 0 0 133 151 1 1
TLR3 ZNFX1 0 0 56 184 1 1
TLR3 DHX9 0 0 243 441 1 1
TLR3 CREB1 0 0 325 325 1 2
TLR3 GSDMD 0 0 267 283 1 2
TLR3 CD22 0 0 193 236 1 1
TLR3 DUSP5 0 0 148 208 1 1
TLR3 GAPDH 0 0 595 625 1 2
TLR3 HAMP 0 0 209 209 1 1
TLR3 OAS2 0 0 503 552 1 1
TLR3 CD83 0 0 556 568 1 1
TLR3 TNFSF15 0 0 210 210 1 1
TLR3 BUD31 0 0 0 226 1 1
TLR3 MAP2K7 0 0 241 289 1 1
TLR3 PELI2 0 0 95 195 1 1
TLR3 CX3CL1 0 0 370 383 1 1
TLR3 CD1A 0 0 326 325 1 1
TLR3 SNRPD3 0 0 0 154 1 1
TLR3 TRIM25 0 0 470 568 1 1
TLR3 ZAP70 0 0 202 241 1 1
TLR3 TLR10 0 0 732 414 1 1
TLR3 STAT4 0 0 310 507 1 1
TLR3 ITGA4 0 0 205 219 1 1
TLR3 SF3A1 0 0 0 196 1 1
TLR3 NFKB1 0 0 378 425 1 2
TLR3 PLK4 0 0 0 165 1 1
TLR3 RELA 0 0 502 514 1 2
TLR3 TRIM38 0 0 363 387 1 1
TLR3 DNTT 0 0 167 167 1 1
TLR3 CCNA2 0 0 67 160 1 1
TLR3 PVR 0 0 188 267 1 1
TLR3 AIF1 0 0 358 372 1 2
TLR3 PIK3CG 0 0 155 241 1 1
TLR3 TFIP11 0 0 0 190 1 1
TLR3 JAK3 0 0 207 256 1 1
TLR3 SH2D3C 0 0 262 262 1 1
TLR3 GZMA 0 0 211 241 1 1
TLR3 ITGAL 0 0 226 240 1 1
TLR3 SERPINB2 0 0 82 338 1 1
TLR3 ENSG00000173366 0 0 911 429 1 1
TLR3 DHX15 0 0 72 175 1 1
TLR3 JUN 0 0 616 631 1 2
TLR3 TAPBP 0 0 241 257 1 1
TLR3 TYK2 0 0 503 534 1 1
TLR3 FYN 0 0 157 199 1 1
TLR3 NFKBIE 0 0 206 231 1 1
TLR3 CLEC6A 0 0 391 413 1 1
TLR3 IFNK 0 0 181 362 1 1
TLR3 JAG1 0 0 218 236 1 1
TLR3 TXNL4A 0 0 0 171 1 1
TLR3 TBL1X 0 0 162 182 1 1
TLR3 LTA 0 0 293 671 1 1
TLR3 SOD1 0 0 194 194 1 2
TLR3 PARP14 0 0 108 217 1 1
TLR3 IL7R 0 0 323 339 1 1
TLR3 RPL3 0 0 0 165 1 1
TLR3 IL36RN 0 0 155 310 1 1
TLR3 EIF2AK2 0 0 460 574 1 2
TLR3 MOB2 0 0 0 154 1 1
TLR3 CNPY3 0 650 422 795 1 1
TLR3 TREM2 0 0 285 300 1 1
TLR3 TNFRSF13C 0 0 284 284 1 1
TLR3 IRF6 0 0 193 193 1 1
TLR3 CD1C 0 0 560 569 1 1
TLR3 IFNAR2 0 0 520 520 1 1
TLR3 SPP1 0 0 258 258 1 2
TLR3 CDKN1A 0 0 125 210 1 2
TLR3 IFNA7 0 0 182 181 1 1
TLR3 TIMP1 0 0 234 246 1 1
TLR3 GPR29 0 0 325 325 1 1
TLR3 CCL18 0 0 230 260 1 1
TLR3 MAT2B 0 0 0 162 1 1
TLR3 GNA12 0 0 0 158 1 1
TLR3 CRLF2 0 0 239 238 1 1
TLR3 AURKA 0 0 60 171 1 2
TLR3 PTPRC 0 0 556 618 1 1
TLR3 CXCR1 0 0 265 265 1 1
TLR3 ITGAV 0 0 117 155 1 1
TLR3 SF3B2 0 0 0 236 1 1
TLR3 BCL10 0 0 264 343 1 1
TLR3 SMDT1 0 0 189 189 1 1
TLR3 RALB 0 0 103 181 1 2
TLR3 ICAM1 0 0 526 534 1 2
TLR3 IGDCC3 0 0 0 195 1 1
TLR3 ROBO1 0 0 0 175 1 1
TLR3 IL21 0 0 91 462 1 1
TLR3 MBL2 270 0 324 493 1 1
TLR3 LSM2 0 0 0 154 1 1
TLR3 BCL3 0 0 81 166 1 1
TLR3 LTB 0 0 143 175 1 1
TLR3 HSP90AA1 0 0 323 333 1 2
TLR3 LBP 0 0 243 242 1 1
TLR3 ATF2 0 0 212 243 1 1
TLR3 CRP 0 0 325 326 1 2
TLR3 SP100 0 0 136 188 1 1
TLR3 SOX2 0 0 184 183 1 2
TLR3 IFIT5 0 0 319 375 1 1
TLR3 CLEC2D 0 0 140 171 1 1
TLR3 SELL 0 0 370 379 1 1
TLR3 RPS2 0 0 0 185 1 1
TLR3 GBP7 0 0 96 178 1 1
TLR3 EPRS 0 0 261 332 1 1
TLR3 C1S 0 0 172 296 1 1
TLR3 NLRX1 0 0 413 414 1 2
TLR3 SELP 0 0 252 282 1 1
TLR3 EMR2 0 0 54 162 1 1
TLR3 MICB 0 0 234 250 1 1
TLR3 SQSTM1 0 0 210 229 1 2
TLR3 MAPK3 0 0 393 408 1 2
TLR3 STK38 0 0 54 178 1 1
TLR3 MMP9 0 0 391 391 1 2
TLR3 THY1 0 0 262 266 1 1
TLR3 ABCG1 0 0 229 241 1 2
TLR3 PDGFRB 0 0 113 158 1 2
TLR3 C21orf91 0 0 161 201 1 1
TLR3 SIRPA 0 0 393 406 1 1
TLR3 EP300 0 0 193 224 1 2
TLR3 SCARB1 0 0 242 241 1 1
TLR3 IL4 0 0 664 668 1 1
TLR3 IL27 0 0 294 294 1 1
TLR3 MSRB2 0 0 0 151 1 1
TLR3 SMAD3 0 0 209 223 1 2
TLR3 IFNA6 0 0 306 306 1 1
TLR3 BIRC3 270 900 249 945 1 1
TLR3 ANXA8 0 0 174 173 1 1
TLR3 IL17F 0 0 321 321 1 1
TLR3 RNF123 270 0 0 281 1 1
TLR3 IL16 0 0 194 224 1 1
TLR3 CARD17 0 0 0 171 1 1
TLR3 IFI6 0 0 279 279 1 1
TLR3 IDO1 0 0 460 459 1 1
TLR3 RPL19 0 0 66 185 1 1
TLR3 OTULIN 0 0 150 172 1 1
TLR3 CCL2 0 0 670 688 1 2
TLR3 GYPC 0 0 233 232 1 1
TLR3 CD68 0 0 391 390 1 2
TLR3 ALB 0 0 467 524 1 2
TLR3 NAA38 0 0 0 154 1 1
TLR3 ILF3 0 0 418 418 1 1
TLR3 CUL1 0 0 95 175 1 1
TLR3 CASP7 0 0 193 235 1 1
TLR3 TYROBP 0 0 324 338 1 1
TLR3 FAM26F 0 0 128 165 1 1
TLR3 GATA1 0 0 108 162 1 1
TLR3 CLEC1A 0 0 141 177 1 1
TLR3 MAF 0 0 181 181 1 1
TLR3 GBP1 0 0 300 365 1 1
TLR3 CRYGC 0 0 378 378 1 1
TLR3 SLC38A4 0 0 0 228 1 1
TLR3 SIGLEC9 297 0 71 349 1 1
TLR3 PPP1CB 0 0 81 216 1 1
TLR3 TRADD 0 0 467 501 1 1
TLR3 AGER 0 0 396 396 1 2
TLR3 EPHA4 0 0 0 155 1 1
TLR3 DDX41 0 0 467 480 1 1
TLR3 SGK494 0 0 0 174 1 1
TLR3 WAC 0 0 0 161 1 1
TLR3 NCF4 0 0 142 160 1 1
TLR3 CDH1 0 0 270 281 1 2
TLR3 MB21D1 0 0 653 660 1 1
TLR3 CD33 0 0 234 343 1 1
TLR3 DUSP10 0 0 94 158 1 1
TLR3 KLRD1 0 0 298 308 1 1
TLR3 CRNKL1 0 0 0 213 1 1
TLR3 MAPK8 0 0 369 405 1 2
TLR3 SERPING1 0 0 226 225 1 1
TLR3 LILRB2 0 0 160 159 1 1
TLR3 ACTN2 0 0 54 176 1 1
TLR3 MAP2K4 0 0 181 195 1 1
TLR3 NTNG1 0 0 0 213 1 1
TLR3 IL1F10 0 0 101 338 1 1
TLR3 BATF3 0 0 467 482 1 1
TLR3 VR1 0 0 195 201 1 1
TLR3 SF3B4 0 0 0 181 1 1
TLR3 SNRNP70 0 0 127 225 1 1
TLR3 DIABLO 0 0 320 319 1 2
TLR3 PPIL6 0 0 57 171 1 1
TLR3 P2RX7 0 0 330 389 1 2
TLR3 CCR1 0 0 342 361 1 1
TLR3 PPP2CB 0 0 0 182 1 1
TLR3 IRF2 0 0 390 404 1 1
TLR3 HSPA4 0 0 393 436 1 1
TLR3 MRPL20 0 0 0 167 1 1
TLR3 DICER1 0 0 343 427 1 1
TLR3 PIK3R1 486 0 113 524 1 1
TLR3 CCR2 0 0 470 481 1 2
TLR3 DDX1 0 0 370 410 1 1
TLR3 ISG20 0 0 415 440 1 1
TLR3 HSP90B1 0 650 410 788 1 1
TLR3 PDCD4 0 0 160 173 1 2
TLR3 HSPB3 0 0 221 221 1 1
TLR3 XPO5 0 0 159 191 1 1
TLR3 CLEC12A 0 0 216 228 1 1
TLR3 CXCL9 0 0 556 566 1 1
TLR3 IL12B 0 0 54 204 1 1
TLR3 TEK 0 0 141 218 1 1
TLR3 PPARA 0 0 210 237 1 2
TLR3 PRRT2 0 0 0 192 1 1
TLR3 TRAF6 835 900 959 999 1 2
TLR3 IL18BP 0 0 171 171 1 1
TLR3 VCAN 0 0 202 226 1 1
TLR3 CXCL11 0 0 459 470 1 1
TLR3 DHX36 0 0 393 471 1 1
TLR3 DUSP12 0 0 137 198 1 1
TLR3 CYCS 0 0 281 296 1 2
TLR3 PRTN3 0 0 218 230 1 1
TLR3 EGF 0 0 325 335 1 2
TLR3 MRPL3 0 0 0 165 1 1
TLR3 FCGRT 0 0 193 210 1 1
TLR3 PCSK1 0 0 339 362 1 1
TLR3 PELI1 0 0 213 393 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0003725 Molecular Function double-stranded RNA binding enables IBA
GO:0003725 Molecular Function double-stranded RNA binding enables IDA
GO:0003725 Molecular Function double-stranded RNA binding enables NAS
GO:0042802 Molecular Function identical protein binding enables IPI
GO:0038187 Molecular Function pattern recognition receptor activity enables IDA
GO:0005515 Molecular Function protein binding enables IPI
GO:0038023 Molecular Function signaling receptor activity enables TAS
GO:0004888 Molecular Function transmembrane signaling receptor activity enables NAS
GO:0007252 Biological Process I-kappaB phosphorylation involved_in IDA
GO:0007254 Biological Process JNK cascade involved_in IEA
GO:0007250 Biological Process activation of NF-kappaB-inducing kinase activity involved_in NAS
GO:0071360 Biological Process cellular response to exogenous dsRNA involved_in IEA
GO:0035458 Biological Process cellular response to interferon-beta involved_in IEA
GO:0071260 Biological Process cellular response to mechanical stimulus involved_in IEP
GO:0071346 Biological Process cellular response to type II interferon involved_in IEA
GO:0098586 Biological Process cellular response to virus involved_in IEA
GO:0071466 Biological Process cellular response to xenobiotic stimulus involved_in IEA
GO:0042742 Biological Process defense response to bacterium involved_in TAS
GO:0051607 Biological Process defense response to virus involved_in IEP
GO:0051607 Biological Process defense response to virus involved_in TAS
GO:0009597 Biological Process detection of virus involved_in NAS
GO:0097191 Biological Process extrinsic apoptotic signaling pathway involved_in IDA
GO:0006972 Biological Process hyperosmotic response involved_in NAS
GO:0090594 Biological Process inflammatory response to wounding involved_in IDA
GO:0045087 Biological Process innate immune response involved_in TAS
GO:0008584 Biological Process male gonad development involved_in IEA
GO:0001774 Biological Process microglial cell activation involved_in IEA
GO:0097527 Biological Process necroptotic signaling pathway involved_in IDA
GO:0045671 Biological Process negative regulation of osteoclast differentiation involved_in NAS
GO:0046330 Biological Process positive regulation of JNK cascade involved_in IDA
GO:0045766 Biological Process positive regulation of angiogenesis involved_in IEA
GO:0043065 Biological Process positive regulation of apoptotic process involved_in IEA
GO:0043123 Biological Process positive regulation of canonical NF-kappaB signal transduction involved_in IEA
GO:0032722 Biological Process positive regulation of chemokine production involved_in IDA
GO:1900017 Biological Process positive regulation of cytokine production involved in inflammatory response involved_in IEA
GO:0010628 Biological Process positive regulation of gene expression involved_in IMP
GO:0050729 Biological Process positive regulation of inflammatory response involved_in IC
GO:0032727 Biological Process positive regulation of interferon-alpha production involved_in IDA
GO:0032728 Biological Process positive regulation of interferon-beta production involved_in IDA
GO:0032728 Biological Process positive regulation of interferon-beta production involved_in IMP
GO:0032728 Biological Process positive regulation of interferon-beta production involved_in ISS
GO:0032735 Biological Process positive regulation of interleukin-12 production involved_in ISS
GO:0032755 Biological Process positive regulation of interleukin-6 production involved_in IDA
GO:0032757 Biological Process positive regulation of interleukin-8 production acts_upstream_of IDA
GO:0060907 Biological Process positive regulation of macrophage cytokine production involved_in IEA
GO:1901224 Biological Process positive regulation of non-canonical NF-kappaB signal transduction involved_in IDA
GO:0045944 Biological Process positive regulation of transcription by RNA polymerase II involved_in ISS
GO:0032760 Biological Process positive regulation of tumor necrosis factor production involved_in ISS
GO:0032729 Biological Process positive regulation of type II interferon production involved_in IDA
GO:0034346 Biological Process positive regulation of type III interferon production involved_in IEA
GO:0002730 Biological Process regulation of dendritic cell cytokine production involved_in IEA
GO:0043331 Biological Process response to dsRNA involved_in IBA
GO:0043330 Biological Process response to exogenous dsRNA acts_upstream_of_or_within IDA
GO:0007165 Biological Process signal transduction involved_in TAS
GO:0034138 Biological Process toll-like receptor 3 signaling pathway involved_in IDA
GO:0002224 Biological Process toll-like receptor signaling pathway involved_in IDA
GO:0034343 Biological Process type III interferon production involved_in IEA
GO:0000139 Cellular Component Golgi membrane located_in TAS
GO:0009986 Cellular Component cell surface NOT located_in IDA
GO:0005737 Cellular Component cytoplasm located_in IDA
GO:0005769 Cellular Component early endosome is_active_in IDA
GO:0036020 Cellular Component endolysosome membrane located_in TAS
GO:0005789 Cellular Component endoplasmic reticulum membrane located_in TAS
GO:0010008 Cellular Component endosome membrane is_active_in ISS
GO:0010008 Cellular Component endosome membrane located_in TAS
GO:0031012 Cellular Component extracellular matrix is_active_in IBA
GO:0005615 Cellular Component extracellular space is_active_in IBA
GO:0005765 Cellular Component lysosomal membrane located_in HDA
GO:0016020 Cellular Component membrane located_in NAS
GO:0005886 Cellular Component plasma membrane located_in IEA
Pathways
Name DB ID
ZBP1(DAI) mediated induction of type I IFNs Reactome R-HSA-1606322
Disease Reactome R-HSA-1643685
Trafficking and processing of endosomal TLR Reactome R-HSA-1679131
Toll Like Receptor 3 (TLR3) Cascade Reactome R-HSA-168164
Innate Immune System Reactome R-HSA-168249
Immune System Reactome R-HSA-168256
Toll-like Receptor Cascades Reactome R-HSA-168898
TICAM1, RIP1-mediated IKK complex recruitment Reactome R-HSA-168927
RIP-mediated NFkB activation via ZBP1 Reactome R-HSA-1810476
Cytosolic sensors of pathogen-associated DNA Reactome R-HSA-1834949
Diseases of Immune System Reactome R-HSA-5260271
Diseases associated with the TLR signaling cascade Reactome R-HSA-5602358
TLR3 deficiency - HSE Reactome R-HSA-5602410
UNC93B1 deficiency - HSE Reactome R-HSA-5602415
TICAM1 deficiency - HSE Reactome R-HSA-5602566
TRAF3 deficiency - HSE Reactome R-HSA-5602571
TLR3-mediated TICAM1-dependent programmed cell death Reactome R-HSA-9013957
TICAM1-dependent activation of IRF3/IRF7 Reactome R-HSA-9013973
TICAM1,TRAF6-dependent induction of TAK1 complex Reactome R-HSA-9014325
mRNA vaccine activation of dendritic cell and induction of IFN-1 (WP5187) WikiPathways WP5187_r122433
Hepatitis B infection (WP4666) WikiPathways WP4666_r123495
Toll-like receptor signaling related to MyD88 (WP3858) WikiPathways WP3858_r117850
SARS coronavirus and innate immunity (WP4912) WikiPathways WP4912_r124650
Type I interferon induction and signaling during SARS-CoV-2 infection (WP4868) WikiPathways WP4868_r124657
Burn wound healing (WP5055) WikiPathways WP5055_r122621
Acute viral myocarditis (WP4298) WikiPathways WP4298_r123508
Toll-like receptor signaling pathway (WP75) WikiPathways WP75_r119233
Mitochondrial immune response to SARS-CoV-2 (WP5038) WikiPathways WP5038_r124641
Fibrin complement receptor 3 signaling pathway (WP4136) WikiPathways WP4136_r120387
Transcripts
Accession Version MolecularType Name NCBI Comments
NM_003265 3 mRNA None NC_000004 Reference