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TP53BP2

tumor protein p53 binding protein 2
General Information
Name tumor protein p53 binding protein 2
Alias
  • apoptosis-stimulating of p53 protein 2
  • BCL2-binding protein
  • apoptosis-stimulating protein of p53, 2
  • renal carcinoma antigen NY-REN-51
  • tumor suppressor p53-binding protein 2
Gene_family Protein phosphatase 1 regulatory subunits|Ankyrin repeat domain containing
organism Homo sapiens
entrez_id 7159
location 1q41
transcript_count 5
exon_count 21
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
    Stringdb Apoptosis-stimulating of p53 protein 2; Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42; Belongs to the ASPP family
    nextProt Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions with proteins such as TP53 (PubMed:12524540). Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of NAE1 to conjugate NEDD8 to CUL1, and thereby decreases NAE1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42.
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
TP53BP2 BioGRID S GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID YWHAE GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
TP53BP2 BioGRID YWHAB GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
TP53BP2 BioGRID GSK3B GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID GSK3A GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID SFN GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID YWHAQ GeneID BioGRID Affinity Capture-MS; Proximity Label-MS; Reconstituted Complex
TP53BP2 BioGRID YWHAZ GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
TP53BP2 BioGRID YWHAH GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
TP53BP2 BioGRID YWHAG GeneID BioGRID Affinity Capture-MS; Proximity Label-MS
TP53BP2 BioGRID PHF21A GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID RCOR1 GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID KDM1A GeneID BioGRID Proximity Label-MS; Two-hybrid
TP53BP2 BioGRID HDAC1 GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID FGFR1 GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID CCNF GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID RNF43 GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID YAP1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Far Western; Protein-peptide; Proximity Label-MS; Reconstituted Complex; Two-hybrid
TP53BP2 BioGRID ORF1ab GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID NAA40 GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID EPS15L1 GeneID BioGRID Affinity Capture-MS
TP53BP2 BioGRID PRPF19 GeneID BioGRID Affinity Capture-MS
TP53BP2 BioGRID FAM168A GeneID BioGRID Affinity Capture-MS
TP53BP2 BioGRID RASSF8 GeneID BioGRID Affinity Capture-MS; Two-hybrid
TP53BP2 BioGRID EMILIN1 GeneID BioGRID Affinity Capture-MS
TP53BP2 BioGRID WWP2 GeneID BioGRID Affinity Capture-MS
TP53BP2 BioGRID SRGAP3 GeneID BioGRID Affinity Capture-MS
TP53BP2 BioGRID BAG2 GeneID BioGRID Affinity Capture-MS
TP53BP2 BioGRID HOMER1 GeneID BioGRID Affinity Capture-MS
TP53BP2 BioGRID HAP1 GeneID BioGRID Affinity Capture-MS
TP53BP2 BioGRID MPDZ GeneID BioGRID Affinity Capture-MS
TP53BP2 BioGRID RASSF7 GeneID BioGRID Affinity Capture-MS
TP53BP2 BioGRID TP53 GeneID BioGRID Affinity Capture-Western; Co-crystal Structure; Reconstituted Complex; Two-hybrid
TP53BP2 BioGRID LURAP1 GeneID BioGRID Affinity Capture-MS
TP53BP2 BioGRID WHAMMP3 GeneID BioGRID Affinity Capture-MS
TP53BP2 BioGRID P4HA3 GeneID BioGRID Affinity Capture-MS
TP53BP2 BioGRID FRMD6 GeneID BioGRID Affinity Capture-MS
TP53BP2 BioGRID CCDC85A GeneID BioGRID Affinity Capture-MS; Two-hybrid
TP53BP2 BioGRID SGF29 GeneID BioGRID Affinity Capture-MS
TP53BP2 BioGRID RPS6 GeneID BioGRID Affinity Capture-MS
TP53BP2 BioGRID PPP1CC GeneID BioGRID Affinity Capture-MS; Proximity Label-MS; Two-hybrid
TP53BP2 BioGRID PPP1CA GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Proximity Label-MS; Reconstituted Complex; Two-hybrid
TP53BP2 BioGRID HSPA2 GeneID BioGRID Affinity Capture-MS
TP53BP2 BioGRID NDC80 GeneID BioGRID Proximity Label-MS; Two-hybrid
TP53BP2 BioGRID TJP2 GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID LATS1 GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID SQSTM1 GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID ZYX GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID VASP GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID TJP1 GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID STX4 GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID PRPH GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID SYNE3 GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID AMOT GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID PARD3 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-localization; Proximity Label-MS
TP53BP2 BioGRID RIGI GeneID BioGRID Affinity Capture-RNA
TP53BP2 BioGRID PCM1 GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID OCLN GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID AFDN GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID KRT19 GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID CTNNB1 GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID CTNNA1 GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID ACTB GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID CREBBP GeneID BioGRID Two-hybrid
TP53BP2 BioGRID PRKCI GeneID BioGRID Affinity Capture-Western
TP53BP2 BioGRID GLI1 GeneID BioGRID Affinity Capture-Western
TP53BP2 BioGRID ENTR1 GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID PLEC GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID H1-2 GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID NEDD4 GeneID BioGRID Protein-peptide; Two-hybrid
TP53BP2 BioGRID MIB1 GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID PPP1CB GeneID BioGRID Affinity Capture-MS; Proximity Label-MS; Two-hybrid
TP53BP2 BioGRID PHF1 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID MOS GeneID BioGRID Two-hybrid
TP53BP2 BioGRID LMNB1 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID HHEX GeneID BioGRID Two-hybrid
TP53BP2 BioGRID GPS2 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID GOLGA1 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID GFAP GeneID BioGRID Two-hybrid
TP53BP2 BioGRID GEM GeneID BioGRID Two-hybrid
TP53BP2 BioGRID DDX6 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID CDC5L GeneID BioGRID Two-hybrid
TP53BP2 BioGRID RASSF10 GeneID BioGRID Affinity Capture-MS; Two-hybrid
TP53BP2 BioGRID INSYN2A GeneID BioGRID Two-hybrid
TP53BP2 BioGRID NHSL2 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID ZNF575 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID CCDC57 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID MTURN GeneID BioGRID Two-hybrid
TP53BP2 BioGRID ZNF438 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID TXLNA GeneID BioGRID Two-hybrid
TP53BP2 BioGRID IQUB GeneID BioGRID Two-hybrid
TP53BP2 BioGRID CCDC13 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID PRPF31 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID APPL1 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID HSF2BP GeneID BioGRID Two-hybrid
TP53BP2 BioGRID RALBP1 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID PIBF1 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID BAIAP2 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID BCAS2 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID TROAP GeneID BioGRID Two-hybrid
TP53BP2 BioGRID DIRAS1 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID EFHC1 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID CEP95 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID UBASH3B GeneID BioGRID Two-hybrid
TP53BP2 BioGRID LMNB2 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID ZGPAT GeneID BioGRID Two-hybrid
TP53BP2 BioGRID PRAM1 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID PLEKHN1 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID ADAMTS12 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID ZFP91 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID TSGA10 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID UBTD1 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID ZNF552 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID PLEKHF2 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID GCC1 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID SCNM1 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID OTUB2 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID RASAL3 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID SHTN1 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID ZBTB4 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID SH3RF1 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID CGN GeneID BioGRID Two-hybrid
TP53BP2 BioGRID RGMA GeneID BioGRID Two-hybrid
TP53BP2 BioGRID YOD1 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID SETD5 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID CEP55 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID UBASH3A GeneID BioGRID Two-hybrid
TP53BP2 BioGRID SH3KBP1 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID BAG3 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID ARHGEF6 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID H2BC9 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID TYK2 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID ELOA GeneID BioGRID Two-hybrid
TP53BP2 BioGRID ATG5 GeneID BioGRID Affinity Capture-Western
TP53BP2 BioGRID PLEKHA4 GeneID BioGRID Affinity Capture-MS
TP53BP2 BioGRID NINL GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID NIN GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID VIRMA GeneID BioGRID Affinity Capture-RNA
TP53BP2 BioGRID NFKB1 GeneID BioGRID Protein-peptide
TP53BP2 BioGRID MYC GeneID BioGRID Affinity Capture-MS
TP53BP2 BioGRID TP53BP2 GeneID BioGRID Co-purification
TP53BP2 BioGRID RELA GeneID BioGRID Reconstituted Complex; Two-hybrid
TP53BP2 BioGRID UBE3A GeneID BioGRID Two-hybrid
TP53BP2 BioGRID LHX4 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID MTMR14 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID AXIN1 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID RXRB GeneID BioGRID Two-hybrid
TP53BP2 BioGRID CRK GeneID BioGRID Two-hybrid
TP53BP2 BioGRID HIF1AN GeneID BioGRID Biochemical Activity; Reconstituted Complex
TP53BP2 BioGRID ITCH GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
TP53BP2 BioGRID APC2 GeneID BioGRID Co-localization; Reconstituted Complex; Two-hybrid
TP53BP2 BioGRID PPP1R7 GeneID BioGRID Affinity Capture-MS
TP53BP2 BioGRID CDH1 GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID CNTRL GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID CEP104 GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID CEP135 GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID Pard6b GeneID BioGRID Affinity Capture-MS
TP53BP2 BioGRID Yap1 GeneID BioGRID Affinity Capture-MS
TP53BP2 BioGRID CEP120 GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID CEP128 GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID SCLT1 GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID SSX2IP GeneID BioGRID Proximity Label-MS; Two-hybrid
TP53BP2 BioGRID CNTROB GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID FBF1 GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID CEP89 GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID PARD6B GeneID BioGRID Affinity Capture-MS
TP53BP2 BioGRID CEP44 GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID CEP97 GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID RPGRIP1 GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID CENPJ GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID PARD6A GeneID BioGRID Affinity Capture-MS
TP53BP2 BioGRID MED4 GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID RPGRIP1L GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID CEP152 GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID CEP162 GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID OFD1 GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID DYNLT1 GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID ODF2 GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID CCDC85C GeneID BioGRID Affinity Capture-MS
TP53BP2 BioGRID CPVL GeneID BioGRID Affinity Capture-MS
TP53BP2 BioGRID CCDC85B GeneID BioGRID Affinity Capture-MS
TP53BP2 BioGRID HSPH1 GeneID BioGRID Affinity Capture-MS
TP53BP2 BioGRID STAM2 GeneID BioGRID Co-fractionation
TP53BP2 BioGRID RASSF9 GeneID BioGRID Affinity Capture-MS
TP53BP2 BioGRID PPP1R3A GeneID BioGRID Affinity Capture-MS
TP53BP2 BioGRID PPP1R2 GeneID BioGRID Affinity Capture-MS
TP53BP2 BioGRID HSPA4 GeneID BioGRID Affinity Capture-MS
TP53BP2 BioGRID ANXA1 GeneID BioGRID Affinity Capture-MS
TP53BP2 BioGRID NXF1 GeneID BioGRID Affinity Capture-RNA; Two-hybrid
TP53BP2 BioGRID EP300 GeneID BioGRID Affinity Capture-Western
TP53BP2 BioGRID CWF19L2 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID ATPAF2 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID CCDC92 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID TBC1D22B GeneID BioGRID Two-hybrid
TP53BP2 BioGRID DCUN1D1 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID NUTM1 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID HNRNPUL1 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID TANK GeneID BioGRID Two-hybrid
TP53BP2 BioGRID TRAF4 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID LMO4 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID H2BC4 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID TCL1A GeneID BioGRID Two-hybrid
TP53BP2 BioGRID ZNF26 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID SIAH1 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID POLR2L GeneID BioGRID Two-hybrid
TP53BP2 BioGRID GRB2 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID BCL2L1 GeneID BioGRID Co-crystal Structure; Protein-peptide; Two-hybrid
TP53BP2 BioGRID BCL2 GeneID BioGRID Protein-peptide; Reconstituted Complex; Two-hybrid
TP53BP2 BioGRID PRKAB2 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID AMOTL2 GeneID BioGRID Affinity Capture-MS
TP53BP2 BioGRID LATS2 GeneID BioGRID Proximity Label-MS
TP53BP2 BioGRID SIAH2 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
TP53BP2 BioGRID ATXN7 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID WWTR1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
TP53BP2 BioGRID NAE1 GeneID BioGRID Affinity Capture-Western
TP53BP2 BioGRID CSNK2B GeneID BioGRID Two-hybrid
TP53BP2 BioGRID PPHLN1 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID MAPK8IP2 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID PLK1 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID BECN1 GeneID BioGRID Affinity Capture-MS
TP53BP2 Protein PPP1CA GeneID HPRD
TP53BP2 Protein MRPL20 GeneID HPRD
TP53BP2 Protein YAP1 GeneID HPRD
TP53BP2 Protein KIF5A GeneID HPRD
TP53BP2 Protein PPP1CC GeneID HPRD
TP53BP2 Protein UTP14A GeneID HPRD
TP53BP2 Protein ATXN7 GeneID HPRD
TP53BP2 Protein YWHAG GeneID HPRD
TP53BP2 Protein UNC119 GeneID HPRD
TP53BP2 Protein USP4 GeneID HPRD
TP53BP2 Protein SUMO2 GeneID HPRD
TP53BP2 Protein MAGI1 GeneID HPRD
TP53BP2 Protein WWP2 GeneID HPRD
TP53BP2 Protein WWP1 GeneID HPRD
TP53BP2 Protein SUMO3 GeneID HPRD
TP53BP2 Protein TP53 GeneID HPRD
TP53BP2 Protein YES1 GeneID HPRD
TP53BP2 Protein RELA GeneID HPRD
TP53BP2 Protein PTN GeneID HPRD
TP53BP2 Protein BCL2 GeneID HPRD
TP53BP2 Protein EEF1A1 GeneID HPRD
TP53BP2 BioGRID YAP1 GeneID BioGRID Reconstituted Complex
TP53BP2 BioGRID MRPL20 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID UTP14A GeneID BioGRID Two-hybrid
TP53BP2 BioGRID UNC119 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID USP4 GeneID BioGRID Two-hybrid
TP53BP2 BioGRID PTN GeneID BioGRID Two-hybrid
TP53BP2 BioGRID KIF5A GeneID BioGRID Two-hybrid
TP53BP2 BioGRID EEF1A1 GeneID BioGRID Two-hybrid
TP53BP2 Nucleotide E2F3 GeneID BIND E2F3 interacts with the TP53BP2 (ASPP2) promoter.
TP53BP2 Nucleotide E2F2 GeneID BIND E2F2 interacts with the TP53BP2 (ASPP2) promoter.
TP53BP2 Protein AAR06173.1 Protein BIND HCV core interacts with ASPP2. This interaction was modeled on a demonstrated interaction between HCV core from Hepatitis C virus genotype 1b from an unspecified strain and ASPP2 from human.
TP53BP2 Nucleotide E2F4 GeneID BIND E2F4 interacts with the TP53BP2 (ASPP2) promoter.
TP53BP2 Protein NAE1 GeneID BIND ASPP2 inhibits APP-BP1-mediated NEDD8 conjugation to cullin-1 and decreases APP-BP1-induced cell proliferation and neuronal apoptosis
TP53BP2 Nucleotide E2F1 GeneID BIND E2F1 interacts with the TP53BP2 (ASPP2) promoter.
TP53BP2 Nucleotide E2F1 GeneID BIND E2F1 (E2F-1) interacts with the TP53BP2 (ASPP2) promoter.
StringDB
A B experiments database textmining combined score hadb nhadb
TP53BP2 C22orf29 0 0 266 266 1 1
TP53BP2 EPB41L2 0 0 82 159 1 1
TP53BP2 RNF25 0 0 101 296 1 1
TP53BP2 RASSF9 131 0 135 398 1 1
TP53BP2 STRN3 0 0 0 273 1 1
TP53BP2 FAIM 0 0 203 288 1 1
TP53BP2 BAHD1 0 0 108 351 1 1
TP53BP2 BTF3 0 0 95 255 1 1
TP53BP2 SDHAF1 0 0 170 169 1 1
TP53BP2 TP53TG5 0 0 203 325 1 1
TP53BP2 NAIP 0 0 166 202 1 1
TP53BP2 PPP1R15A 0 0 193 198 1 2
TP53BP2 ITCH 486 0 95 539 1 1
TP53BP2 PPP1R2 131 0 105 188 1 1
TP53BP2 ELOA3B 0 0 0 248 1 1
TP53BP2 FMR1 0 0 0 187 1 1
TP53BP2 CDC7 0 0 0 188 1 1
TP53BP2 CD70 0 0 105 196 1 1
TP53BP2 DGUOK 0 0 0 213 1 1
TP53BP2 PLEKHA4 270 0 0 293 1 1
TP53BP2 FOXK2 0 0 55 226 1 1
TP53BP2 DRAM1 0 0 234 234 1 2
TP53BP2 PPEF2 0 0 0 175 1 1
TP53BP2 CD3EAP 0 0 0 183 1 1
TP53BP2 PGAM1 0 0 57 233 1 1
TP53BP2 RAB3C 299 0 0 299 1 1
TP53BP2 PARD6A 459 0 0 459 1 1
TP53BP2 GADD45A 0 0 324 341 1 1
TP53BP2 RFX3 0 0 73 277 1 1
TP53BP2 SYNE1 0 0 0 267 1 1
TP53BP2 RFXANK 0 0 202 202 1 1
TP53BP2 STRN 0 0 0 273 1 1
TP53BP2 VGLL4 0 0 137 160 1 1
TP53BP2 UVRAG 0 0 212 212 1 2
TP53BP2 TP53I13 0 0 407 407 1 1
TP53BP2 MRPS18A 0 0 141 371 1 1
TP53BP2 PPP2CA 0 0 74 211 1 1
TP53BP2 TP53INP2 0 0 101 157 1 2
TP53BP2 BAD 0 0 766 766 1 2
TP53BP2 KAT2B 0 0 134 158 1 1
TP53BP2 DMTF1 0 0 170 189 1 1
TP53BP2 RAPGEF5 0 0 95 212 1 1
TP53BP2 IRS1 0 0 383 474 1 2
TP53BP2 RRAD 0 0 321 326 1 1
TP53BP2 BCL2L2 472 0 225 591 1 1
TP53BP2 WDR6 0 0 0 190 1 1
TP53BP2 IRAK2 0 0 46 214 1 1
TP53BP2 HDAC7 0 0 0 200 1 1
TP53BP2 VPS37B 0 0 103 265 1 1
TP53BP2 CCND1 0 0 181 181 1 2
TP53BP2 TBC1D17 0 0 0 200 1 1
TP53BP2 SLC13A3 0 0 75 325 1 1
TP53BP2 TP53I3 0 900 284 944 1 1
TP53BP2 E2F8 0 0 108 150 1 1
TP53BP2 DFFA 0 0 120 272 1 1
TP53BP2 BAK1 0 0 163 218 1 2
TP53BP2 PPP2R5E 0 0 158 165 1 1
TP53BP2 BCL2 680 0 167 726 1 2
TP53BP2 STK31 0 0 0 210 1 1
TP53BP2 CCDC106 0 0 258 258 1 1
TP53BP2 ZNF507 0 0 0 189 1 1
TP53BP2 MAGI2 0 0 56 210 1 1
TP53BP2 HRK 0 0 205 220 1 1
TP53BP2 NEK6 0 0 0 173 1 1
TP53BP2 MYCBP2 0 0 150 211 1 1
TP53BP2 SAV1 0 0 180 179 1 1
TP53BP2 NDC80 118 0 101 225 1 1
TP53BP2 LRRK1 0 0 112 232 1 1
TP53BP2 TCHP 0 0 325 325 1 1
TP53BP2 RASSF1 0 0 258 264 1 1
TP53BP2 ZNF556 0 0 260 260 1 1
TP53BP2 CCDC92 284 0 0 284 1 1
TP53BP2 PPM1D 0 0 218 218 1 1
TP53BP2 VDAC1 0 0 66 162 1 2
TP53BP2 BNIP3L 0 0 217 318 1 2
TP53BP2 PLLP 0 0 90 152 1 1
TP53BP2 USP7 0 0 136 154 1 1
TP53BP2 TEP1 0 0 122 197 1 1
TP53BP2 PPIL3 0 0 141 231 1 1
TP53BP2 RB1 0 0 141 151 1 2
TP53BP2 WDR83 0 0 108 171 1 1
TP53BP2 YWHAB 171 0 0 171 1 1
TP53BP2 BBOX1 0 0 54 199 1 1
TP53BP2 ATXN2 0 0 63 318 1 1
TP53BP2 TP53I11 0 0 175 189 1 1
TP53BP2 IRS4 270 0 0 287 1 1
TP53BP2 SRC 0 0 403 448 1 2
TP53BP2 PRUNE 0 0 0 192 1 1
TP53BP2 BNIP1 0 0 153 162 1 2
TP53BP2 BIRC6 0 0 67 206 1 1
TP53BP2 LGALS3 0 0 451 451 1 2
TP53BP2 S100A6 0 0 0 192 1 1
TP53BP2 TP53INP1 0 0 241 320 1 2
TP53BP2 PREPL 0 0 112 216 1 1
TP53BP2 WWP2 462 0 0 489 1 1
TP53BP2 PPP4R1 0 0 161 434 1 1
TP53BP2 NDUFB3 0 0 95 151 1 1
TP53BP2 PYGO1 287 0 0 286 1 1
TP53BP2 PPP3CA 0 0 53 247 1 1
TP53BP2 WWOX 0 0 155 263 1 1
TP53BP2 BTBD2 0 0 143 275 1 1
TP53BP2 CYYR1 0 0 230 229 1 1
TP53BP2 PEX6 0 0 67 476 1 1
TP53BP2 SRGAP3 288 0 0 306 1 1
TP53BP2 CCDC101 244 0 0 243 1 1
TP53BP2 CARD6 0 0 0 258 1 1
TP53BP2 ITM2B 0 0 85 166 1 1
TP53BP2 YES1 213 0 89 308 1 1
TP53BP2 BBC3 0 900 267 923 1 2
TP53BP2 HERC1 0 0 762 796 1 1
TP53BP2 MTMR14 366 0 0 366 1 2
TP53BP2 ETF1 0 0 46 262 1 1
TP53BP2 AKT1 0 0 277 289 1 2
TP53BP2 UBE3A 178 0 143 335 1 1
TP53BP2 CNIH4 0 0 269 269 1 1
TP53BP2 PPP1R13L 0 0 872 280 1 1
TP53BP2 RAB40C 0 0 270 270 1 1
TP53BP2 USO1 0 0 0 188 1 1
TP53BP2 CARD8 0 0 83 326 1 1
TP53BP2 SYNE2 0 0 0 160 1 1
TP53BP2 FAS 0 900 145 923 1 2
TP53BP2 PPP2R4 0 0 155 154 1 1
TP53BP2 XIAP 0 0 107 158 1 2
TP53BP2 E2F4 0 0 117 274 1 1
TP53BP2 ARID3C 0 0 216 216 1 1
TP53BP2 AMPD3 0 0 74 171 1 1
TP53BP2 BIN2 0 0 160 189 1 1
TP53BP2 NIF3L1 0 0 181 299 1 1
TP53BP2 NOD1 0 0 150 208 1 2
TP53BP2 WBP2 0 0 349 395 1 1
TP53BP2 FRMD6 774 0 0 774 1 1
TP53BP2 SPATA4 0 0 162 167 1 1
TP53BP2 CDKN2B 0 0 142 201 1 1
TP53BP2 PMAIP1 0 0 294 294 1 2
TP53BP2 PIAS1 0 0 161 161 1 1
TP53BP2 TOLLIP 0 0 0 248 1 1
TP53BP2 PTGER3 0 0 45 171 1 1
TP53BP2 TCEB3B 0 0 0 248 1 1
TP53BP2 LRRK2 0 0 0 171 1 2
TP53BP2 TRAF3 0 0 0 230 1 2
TP53BP2 BECN1 142 0 370 436 1 2
TP53BP2 FAM160A2 0 0 0 175 1 1
TP53BP2 CAMK2B 0 0 48 297 1 1
TP53BP2 CLDN8 0 0 57 260 1 1
TP53BP2 KRAS 0 0 142 184 1 2
TP53BP2 CAPN8 0 0 248 265 1 1
TP53BP2 RPF1 0 0 92 154 1 1
TP53BP2 HSPA5 0 0 88 185 1 2
TP53BP2 E2F1 0 0 166 172 1 2
TP53BP2 FOXK1 0 0 62 460 1 1
TP53BP2 EMR3 0 0 100 278 1 1
TP53BP2 LIN54 0 0 0 157 1 1
TP53BP2 CSRNP1 0 0 90 227 1 1
TP53BP2 TADA3 0 0 193 198 1 1
TP53BP2 MCM6 0 0 75 283 1 1
TP53BP2 PTPN11 0 0 208 240 1 1
TP53BP2 S100A8 0 0 977 977 1 2
TP53BP2 YWHAZ 219 0 96 268 1 1
TP53BP2 AMOTL2 171 0 66 207 1 1
TP53BP2 AIFM3 0 0 97 369 1 1
TP53BP2 HNRNPA0 0 0 74 216 1 1
TP53BP2 IGSF6 0 0 94 177 1 1
TP53BP2 MATK 0 0 0 270 1 1
TP53BP2 HIGD1A 0 0 205 205 1 1
TP53BP2 LTBR 0 0 45 176 1 1
TP53BP2 YWHAH 680 0 71 698 1 1
TP53BP2 TP53TG3B 0 0 293 293 1 1
TP53BP2 MAP3K10 0 0 61 160 1 1
TP53BP2 JAKMIP1 0 0 93 155 1 1
TP53BP2 HDAC1 0 0 166 165 1 2
TP53BP2 RASSF7 736 0 194 829 1 1
TP53BP2 IQCA1 0 0 0 188 1 1
TP53BP2 SFN 0 0 184 183 1 2
TP53BP2 PTPN12 0 0 53 152 1 1
TP53BP2 CDKN2A 0 0 314 313 1 2
TP53BP2 PPP6C 0 0 124 247 1 1
TP53BP2 XRCC5 0 0 145 163 1 1
TP53BP2 CCNG1 0 0 112 212 1 1
TP53BP2 DDX42 0 0 909 909 1 1
TP53BP2 TCEB3CL 0 0 0 248 1 1
TP53BP2 FGFRL1 0 0 140 226 1 1
TP53BP2 BAIAP2 137 0 0 160 1 1
TP53BP2 TNFRSF10B 0 0 180 185 1 2
TP53BP2 ATG12 0 0 233 232 1 2
TP53BP2 TP53TG3D 0 0 293 293 1 1
TP53BP2 TNFRSF21 0 0 134 225 1 1
TP53BP2 DAXX 0 0 167 177 1 1
TP53BP2 CASP3 0 0 261 261 1 2
TP53BP2 RNF152 0 0 0 189 1 1
TP53BP2 CDCA2 0 0 220 220 1 1
TP53BP2 HAAO 0 0 82 281 1 1
TP53BP2 EGLN1 0 0 174 191 1 1
TP53BP2 FAM160A1 0 0 0 175 1 1
TP53BP2 LNX1 0 0 278 313 1 1
TP53BP2 BRCA2 0 0 147 163 1 1
TP53BP2 PITPNM3 0 0 90 165 1 1
TP53BP2 NUTF2 270 0 0 270 1 1
TP53BP2 TXN2 0 0 0 305 1 1
TP53BP2 VEGFA 0 0 134 188 1 2
TP53BP2 TRPV3 0 0 93 155 1 1
TP53BP2 PTEN 0 0 207 207 1 2
TP53BP2 NEK7 0 0 0 173 1 1
TP53BP2 EIF3C 0 0 145 168 1 1
TP53BP2 NREP 0 0 134 168 1 1
TP53BP2 E2F5 0 0 96 167 1 1
TP53BP2 NEURL4 0 0 202 324 1 1
TP53BP2 NFKBIA 0 0 170 208 1 2
TP53BP2 SDCCAG3 196 0 0 196 1 1
TP53BP2 CCDC115 0 0 155 215 1 1
TP53BP2 LRRFIP2 0 0 92 464 1 1
TP53BP2 ENSG00000205457 0 0 293 293 1 1
TP53BP2 BAG1 0 0 650 650 1 2
TP53BP2 MARK2 0 0 413 551 1 1
TP53BP2 E2F3 0 0 134 186 1 1
TP53BP2 AXIN1 94 0 104 187 1 1
TP53BP2 UNG 0 0 0 188 1 1
TP53BP2 PTPN20A 0 0 155 154 1 1
TP53BP2 TEAD1 0 0 150 222 1 1
TP53BP2 ATM 0 0 231 230 1 2
TP53BP2 CRB2 0 0 329 330 1 1
TP53BP2 DYX1C1 0 0 0 163 1 1
TP53BP2 TAF4B 0 0 219 236 1 1
TP53BP2 MDM4 0 0 182 187 1 1
TP53BP2 ATG7 0 0 218 218 1 2
TP53BP2 TJP1 0 0 148 166 1 1
TP53BP2 TRAIP 0 0 0 219 1 1
TP53BP2 EXOC4 0 0 0 215 1 1
TP53BP2 BARX1 0 0 89 505 1 1
TP53BP2 SPHK2 0 0 105 199 1 1
TP53BP2 LSS 0 0 57 154 1 1
TP53BP2 MAP1LC3B 0 0 185 185 1 2
TP53BP2 PTPRH 0 0 96 191 1 1
TP53BP2 SUGT1 0 0 170 169 1 1
TP53BP2 ENSG00000205457 0 0 293 293 1 1
TP53BP2 ZBTB4 94 0 108 159 1 1
TP53BP2 RPS18 0 0 107 162 1 1
TP53BP2 C20orf27 0 0 0 271 1 1
TP53BP2 LATS1 0 0 332 381 1 1
TP53BP2 PARD6B 276 0 74 300 1 1
TP53BP2 NUMA1 0 0 81 153 1 1
TP53BP2 FANCL 0 0 46 213 1 1
TP53BP2 SLX4 0 0 47 152 1 1
TP53BP2 TP53BP1 0 0 658 666 1 1
TP53BP2 TCEB3C 0 0 0 248 1 1
TP53BP2 RAB22A 0 0 57 273 1 1
TP53BP2 MCL1 0 0 214 214 1 2
TP53BP2 OVOL1 0 0 82 245 1 1
TP53BP2 NUAK1 0 0 55 392 1 1
TP53BP2 SMARCA4 0 0 53 188 1 1
TP53BP2 SIRT1 0 0 161 161 1 2
TP53BP2 HOMER1 196 0 0 196 1 1
TP53BP2 SMAD7 0 0 171 171 1 1
TP53BP2 PPP1CA 871 800 574 990 1 1
TP53BP2 MSH2 0 0 81 338 1 1
TP53BP2 CNIH3 0 0 264 264 1 1
TP53BP2 PPP5D1 0 0 0 175 1 1
TP53BP2 ATG5 270 0 861 894 1 2
TP53BP2 BRD8 0 0 0 300 1 1
TP53BP2 NKX1-1 0 0 0 171 1 1
TP53BP2 SPAG6 0 0 77 285 1 1
TP53BP2 TP63 297 600 456 844 1 2
TP53BP2 YAP1 878 800 640 990 1 2
TP53BP2 MIB1 114 0 0 150 1 1
TP53BP2 IGF1R 0 0 85 150 1 2
TP53BP2 SLCO4C1 0 0 85 297 1 1
TP53BP2 APEX1 0 0 46 454 1 1
TP53BP2 OR52J3 0 0 218 301 1 1
TP53BP2 PPP5C 0 0 0 175 1 1
TP53BP2 PPP1R7 169 0 134 416 1 1
TP53BP2 MYC 66 0 217 237 1 2
TP53BP2 APC2 270 0 233 416 1 1
TP53BP2 ILK 0 0 56 225 1 1
TP53BP2 CCNH 0 0 138 156 1 1
TP53BP2 WWTR1 270 800 158 870 1 1
TP53BP2 NR2F6 0 0 69 334 1 1
TP53BP2 RPL15 0 0 123 276 1 1
TP53BP2 CYP7B1 0 0 46 212 1 1
TP53BP2 TRAF2 0 0 101 229 1 2
TP53BP2 STRN4 0 0 0 225 1 1
TP53BP2 PPP3CB 0 0 0 237 1 1
TP53BP2 EGLN3 0 0 134 479 1 1
TP53BP2 WDR64 0 0 0 199 1 1
TP53BP2 CASP8AP2 0 0 126 223 1 1
TP53BP2 PARD3 744 0 690 917 1 1
TP53BP2 HIST1H2BH 163 0 0 163 1 1
TP53BP2 FLII 0 0 61 327 1 1
TP53BP2 JMY 0 0 392 433 1 1
TP53BP2 PPP3CC 0 0 0 237 1 1
TP53BP2 TTN 0 0 91 212 1 1
TP53BP2 NOL3 0 0 135 283 1 1
TP53BP2 MDC1 0 0 398 398 1 1
TP53BP2 CIDEB 0 0 157 241 1 1
TP53BP2 BRCA1 0 0 218 218 1 2
TP53BP2 CAND1 0 0 112 222 1 1
TP53BP2 MAGI1 213 0 0 341 1 1
TP53BP2 IKZF3 0 0 42 298 1 1
TP53BP2 PGAM5 0 0 74 326 1 1
TP53BP2 SPAG17 0 0 107 323 1 1
TP53BP2 KIAA1549L 0 0 0 177 1 1
TP53BP2 PPP1R13B 0 650 913 673 1 1
TP53BP2 CYB5R2 0 0 108 350 1 1
TP53BP2 ENSG00000272772 0 0 0 175 1 1
TP53BP2 FADD 0 0 181 186 1 2
TP53BP2 CCDC67 0 0 0 207 1 1
TP53BP2 NEDD8 0 0 150 188 1 2
TP53BP2 SPATA22 0 0 113 251 1 1
TP53BP2 EGFR 0 0 193 222 1 2
TP53BP2 CFLAR 0 0 91 183 1 2
TP53BP2 CDK4 0 0 128 182 1 2
TP53BP2 PPP1CC 871 800 447 988 1 1
TP53BP2 TP53 978 600 989 999 1 2
TP53BP2 MDM2 0 0 425 429 1 2
TP53BP2 ERCC2 0 0 75 173 1 1
TP53BP2 MARK1 0 0 108 218 1 1
TP53BP2 CREBZF 0 0 95 157 1 1
TP53BP2 BNIP2 0 0 256 256 1 1
TP53BP2 ADAT2 0 0 134 221 1 1
TP53BP2 NUP153 270 0 60 300 1 1
TP53BP2 CRADD 0 0 181 318 1 1
TP53BP2 RAF1 0 0 171 184 1 2
TP53BP2 SIAH2 270 0 154 356 1 1
TP53BP2 SLC22A6 0 0 60 223 1 1
TP53BP2 HUWE1 0 0 251 272 1 1
TP53BP2 PCDHB4 0 0 134 266 1 1
TP53BP2 CLDN17 0 0 0 188 1 1
TP53BP2 KIAA1549 0 0 0 266 1 1
TP53BP2 TP53RK 0 0 167 252 1 1
TP53BP2 APAF1 0 0 234 243 1 2
TP53BP2 TBRG1 0 0 97 491 1 1
TP53BP2 CSRNP3 0 0 139 358 1 1
TP53BP2 TCEB3CL2 0 0 0 248 1 1
TP53BP2 PPP1R11 0 0 0 281 1 1
TP53BP2 SIVA1 0 0 75 174 1 1
TP53BP2 MKRN1 0 0 143 338 1 1
TP53BP2 ZNF532 0 0 123 215 1 1
TP53BP2 NF2 0 0 158 157 1 1
TP53BP2 UACA 0 0 181 453 1 1
TP53BP2 SUPV3L1 0 0 0 216 1 1
TP53BP2 SUMO2 213 0 102 263 1 1
TP53BP2 KIAA1429 270 0 0 270 1 1
TP53BP2 TARSL2 113 0 0 151 1 1
TP53BP2 LATS2 171 0 294 434 1 1
TP53BP2 CNTD2 0 0 150 240 1 1
TP53BP2 BAG3 65 0 276 314 1 2
TP53BP2 NEDD4 113 0 451 518 1 2
TP53BP2 EDN1 0 0 0 186 1 1
TP53BP2 HIF1A 0 0 166 165 1 2
TP53BP2 RASSF10 145 0 203 494 1 1
TP53BP2 NAE1 462 0 458 727 1 1
TP53BP2 TGFBRAP1 0 0 54 185 1 1
TP53BP2 MYOM2 0 0 0 461 1 1
TP53BP2 ERBB2IP 0 0 260 294 1 1
TP53BP2 TNFRSF1B 0 0 72 206 1 1
TP53BP2 TBC1D22B 476 0 0 476 1 1
TP53BP2 DDX18 0 0 124 162 1 1
TP53BP2 HRAS 0 0 219 219 1 2
TP53BP2 CTNNB1 270 0 674 763 1 2
TP53BP2 WDR26 0 0 322 348 1 1
TP53BP2 MSH6 0 0 108 204 1 1
TP53BP2 CDK2 0 0 180 192 1 2
TP53BP2 APP 291 0 453 595 1 2
TP53BP2 FAM53A 0 0 155 169 1 1
TP53BP2 CDC73 0 0 75 246 1 1
TP53BP2 MTOR 0 0 125 154 1 2
TP53BP2 RAD51 0 0 150 166 1 2
TP53BP2 E2F2 0 0 165 325 1 1
TP53BP2 HSD11B1L 0 0 150 281 1 1
TP53BP2 TRAF4 112 0 95 281 1 1
TP53BP2 APEX2 0 0 0 270 1 1
TP53BP2 TP53TG3 0 0 285 284 1 1
TP53BP2 NOTCH1 0 0 167 168 1 2
TP53BP2 BCL2L2-PABPN1 0 0 205 205 1 1
TP53BP2 CCDC85B 131 0 0 291 1 1
TP53BP2 TNFRSF1A 0 0 122 253 1 1
TP53BP2 PPP4C 0 0 159 286 1 1
TP53BP2 SLC17A3 0 0 90 247 1 1
TP53BP2 PPP1R12A 0 0 150 168 1 1
TP53BP2 PIK3C3 0 0 202 208 1 2
TP53BP2 GPR37 0 0 122 248 1 1
TP53BP2 MPP5 247 0 90 349 1 1
TP53BP2 BTF3L4 0 0 156 385 1 1
TP53BP2 WWP1 213 0 450 571 1 1
TP53BP2 BIRC2 0 0 126 205 1 1
TP53BP2 DHX9 0 0 0 206 1 1
TP53BP2 G0S2 0 0 57 314 1 1
TP53BP2 RECK 0 0 141 194 1 1
TP53BP2 STAM2 272 0 75 315 1 1
TP53BP2 CREBBP 0 0 0 187 1 1
TP53BP2 SC5D 0 0 66 167 1 1
TP53BP2 SIAH1 129 0 150 228 1 1
TP53BP2 PLK1 64 0 155 175 1 2
TP53BP2 PLEC 88 0 50 153 1 1
TP53BP2 AGAP2 0 0 0 181 1 1
TP53BP2 ANXA5 0 0 252 265 1 2
TP53BP2 CCDC85C 131 0 0 382 1 1
TP53BP2 MBD1 0 0 282 282 1 1
TP53BP2 AMOTL1 0 0 171 181 1 1
TP53BP2 FAM126B 0 0 161 244 1 1
TP53BP2 NFKB1 0 0 210 264 1 2
TP53BP2 XPA 0 0 57 210 1 1
TP53BP2 MAPK8IP1 0 0 123 245 1 1
TP53BP2 BCL2L1 432 0 355 618 1 2
TP53BP2 PLSCR4 0 0 105 166 1 1
TP53BP2 RELA 651 0 203 710 1 2
TP53BP2 PIK3R4 0 0 134 188 1 2
TP53BP2 RAN 417 0 0 416 1 2
TP53BP2 XPOT 0 0 90 156 1 1
TP53BP2 CASP6 0 0 181 187 1 1
TP53BP2 PGAM4 0 0 0 221 1 1
TP53BP2 FKBP8 0 0 60 347 1 1
TP53BP2 ABL1 0 0 329 341 1 1
TP53BP2 MAP2K7 0 0 155 154 1 1
TP53BP2 BCCIP 0 0 81 484 1 1
TP53BP2 TM7SF2 0 0 96 235 1 1
TP53BP2 CCDC85A 114 0 0 277 1 1
TP53BP2 BNIPL 0 0 210 499 1 1
TP53BP2 WWC1 0 0 229 299 1 1
TP53BP2 TOPORS 0 0 277 292 1 1
TP53BP2 SLC39A9 0 0 90 337 1 1
TP53BP2 ATG14 0 0 161 161 1 2
TP53BP2 GAPDH 0 0 234 234 1 2
TP53BP2 ARID5A 0 0 85 181 1 1
TP53BP2 SLC22A18 0 0 72 216 1 1
TP53BP2 DAPK1 0 0 181 301 1 2
TP53BP2 TAZ 0 0 75 173 1 1
TP53BP2 NTHL1 0 0 0 161 1 1
TP53BP2 BCL2L11 0 0 236 481 1 2
TP53BP2 DISP1 0 0 260 260 1 1
TP53BP2 PHF12 0 0 0 169 1 1
TP53BP2 HSPA1A 0 0 155 154 1 1
TP53BP2 CHEK1 0 0 193 199 1 2
TP53BP2 CCNA2 0 0 161 184 1 1
TP53BP2 MB21D2 0 0 150 337 1 1
TP53BP2 RIPK2 0 0 57 223 1 2
TP53BP2 CRK 168 0 165 275 1 1
TP53BP2 WBSCR16 0 0 92 289 1 1
TP53BP2 EI24 0 0 286 286 1 2
TP53BP2 RUNX3 0 0 150 162 1 1
TP53BP2 APBB1 0 0 68 159 1 1
TP53BP2 BIK 0 0 203 252 1 2
TP53BP2 IRS2 0 0 108 217 1 1
TP53BP2 PHACTR4 0 0 134 188 1 1
TP53BP2 GRB2 112 0 135 256 1 1
TP53BP2 CEP55 69 0 108 166 1 1
TP53BP2 CAPN2 0 0 141 168 1 2
TP53BP2 C8orf46 0 0 162 161 1 1
TP53BP2 ZEB1 0 0 138 170 1 2
TP53BP2 SLC10A2 0 0 46 212 1 1
TP53BP2 BCL10 0 0 107 203 1 1
TP53BP2 METTL7A 0 0 112 272 1 1
TP53BP2 CIART 0 0 112 249 1 1
TP53BP2 BAX 0 900 83 904 1 2
TP53BP2 CASZ1 0 0 90 229 1 1
TP53BP2 BID 0 0 96 187 1 2
TP53BP2 CDCA7 0 0 67 209 1 1
TP53BP2 FGL2 0 0 113 221 1 1
TP53BP2 CDKN1A 0 0 387 386 1 2
TP53BP2 PEX7 0 0 66 210 1 1
TP53BP2 BNIP3 0 0 261 261 1 2
TP53BP2 ATP6V1G2 0 0 91 186 1 1
TP53BP2 SLTM 0 0 123 211 1 1
TP53BP2 CAV2 0 0 57 156 1 1
TP53BP2 DNMT1 0 0 145 175 1 2
TP53BP2 MSMO1 0 0 54 151 1 1
TP53BP2 CD40 0 0 0 239 1 2
TP53BP2 ACTB 0 0 189 189 1 2
TP53BP2 RASSF8 871 0 285 968 1 1
TP53BP2 TP73 853 600 261 957 1 2
TP53BP2 SETDB1 0 0 367 367 1 1
TP53BP2 CTBP1 0 0 45 346 1 1
TP53BP2 CUL1 0 0 138 156 1 1
TP53BP2 MRPL41 0 0 287 286 1 1
TP53BP2 IL16 0 0 68 167 1 1
TP53BP2 LRRFIP1 0 0 55 154 1 1
TP53BP2 CASP8 0 0 233 280 1 2
TP53BP2 BIRC3 0 0 123 203 1 1
TP53BP2 TNFRSF10A 0 0 160 166 1 1
TP53BP2 PPEF1 0 0 46 180 1 1
TP53BP2 TP53AIP1 0 0 402 403 1 1
TP53BP2 DAG1 0 0 69 414 1 1
TP53BP2 ROCK1 0 0 51 321 1 2
TP53BP2 EP300 270 0 183 400 1 2
TP53BP2 OR51A7 0 0 216 272 1 1
TP53BP2 ANKRD55 0 0 92 171 1 1
TP53BP2 CEP152 76 0 0 235 1 1
TP53BP2 SPAG8 0 0 138 360 1 1
TP53BP2 FBXO28 0 0 308 307 1 1
TP53BP2 HES7 0 0 67 247 1 1
TP53BP2 CDH1 367 0 243 511 1 2
TP53BP2 OTUB2 131 0 0 161 1 1
TP53BP2 ATP13A4 0 0 134 227 1 1
TP53BP2 YWHAG 131 0 73 172 1 1
TP53BP2 ENSG00000278848 0 0 293 293 1 1
TP53BP2 CDK6 0 0 113 250 1 2
TP53BP2 SPEF2 0 0 97 342 1 1
TP53BP2 MAGI3 0 0 0 197 1 1
TP53BP2 H2AFX 0 0 292 292 1 1
TP53BP2 ROCK2 0 0 0 155 1 1
TP53BP2 PPP1CB 474 800 453 952 1 1
TP53BP2 ERCC4 0 0 63 162 1 1
TP53BP2 PIK3AP1 0 0 74 176 1 1
TP53BP2 TEAD3 0 0 95 209 1 1
TP53BP2 FANCM 0 0 45 463 1 1
TP53BP2 TCEB3 75 0 90 507 1 1
TP53BP2 SMARCE1 0 0 0 258 1 1
TP53BP2 BEND5 0 0 165 165 1 1
TP53BP2 PLCD4 0 0 103 163 1 1
TP53BP2 CSK 0 0 165 364 1 1
TP53BP2 PPP1R10 0 0 288 298 1 1
TP53BP2 PPP2CB 0 0 0 183 1 1
TP53BP2 DIABLO 0 0 133 264 1 2
TP53BP2 HIST2H3PS2 0 0 154 155 1 1
TP53BP2 E4F1 0 0 96 389 1 1
TP53BP2 COX7C 0 0 73 217 1 1
TP53BP2 PEX5 0 0 70 392 1 1
TP53BP2 RASSF2 0 0 81 240 1 1
TP53BP2 MYLPF 0 0 45 189 1 1
TP53BP2 GRB7 0 0 143 234 1 1
TP53BP2 AMOT 171 0 262 362 1 1
TP53BP2 SUMO3 213 0 0 213 1 1
TP53BP2 NRXN2 0 0 59 153 1 1
TP53BP2 PAWR 0 0 74 466 1 1
TP53BP2 PRKAB2 218 0 0 218 1 1
TP53BP2 RGMA 163 0 0 163 1 1
TP53BP2 TNRC18 0 0 0 190 1 1
TP53BP2 BFAR 0 0 96 251 1 1
TP53BP2 RAB31 0 0 58 258 1 1
TP53BP2 TBC1D15 0 0 0 200 1 1
TP53BP2 CASP9 0 0 156 155 1 2
TP53BP2 SHOC2 0 0 98 158 1 1
TP53BP2 CHEK2 0 0 217 231 1 1
TP53BP2 CYCS 0 0 170 169 1 2
TP53BP2 PPP4R2 0 0 155 243 1 1
TP53BP2 PSMD4 0 0 58 187 1 1
TP53BP2 PDCD4 0 0 134 188 1 2
TP53BP2 CLEC12A 0 0 55 169 1 1
TP53BP2 CSDE1 0 0 180 186 1 1
TP53BP2 HIF1AN 847 0 397 904 1 1
TP53BP2 CSE1L 0 0 181 186 1 1
TP53BP2 HSPA4 131 0 438 490 1 1
TP53BP2 RPLP1 0 0 75 169 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0051059 Molecular Function NF-kappaB binding enables IPI
GO:0017124 Molecular Function SH3 domain binding enables IEA
GO:0042802 Molecular Function identical protein binding enables IPI
GO:0002039 Molecular Function p53 binding enables IBA
GO:0002039 Molecular Function p53 binding enables IPI
GO:0005515 Molecular Function protein binding enables IPI
GO:0007049 Biological Process cell cycle involved_in IEA
GO:0072332 Biological Process intrinsic apoptotic signaling pathway by p53 class mediator involved_in IDA
GO:0045786 Biological Process negative regulation of cell cycle involved_in TAS
GO:1900119 Biological Process positive regulation of execution phase of apoptosis involved_in IMP
GO:0007165 Biological Process signal transduction involved_in TAS
GO:0030054 Cellular Component cell junction located_in IDA
GO:0005737 Cellular Component cytoplasm located_in IDA
GO:0005737 Cellular Component cytoplasm located_in TAS
GO:0005829 Cellular Component cytosol located_in IDA
GO:0005654 Cellular Component nucleoplasm located_in TAS
GO:0005634 Cellular Component nucleus is_active_in IBA
GO:0005634 Cellular Component nucleus located_in IDA
GO:0048471 Cellular Component perinuclear region of cytoplasm colocalizes_with IDA
GO:0048471 Cellular Component perinuclear region of cytoplasm located_in IDA
Pathways
Name DB ID
Apoptosis Reactome R-HSA-109581
Intrinsic Pathway for Apoptosis Reactome R-HSA-109606
Activation of BH3-only proteins Reactome R-HSA-114452
Activation of PUMA and translocation to mitochondria Reactome R-HSA-139915
Generic Transcription Pathway Reactome R-HSA-212436
Transcriptional Regulation by TP53 Reactome R-HSA-3700989
Programmed Cell Death Reactome R-HSA-5357801
Regulation of TP53 Activity Reactome R-HSA-5633007
TP53 Regulates Transcription of Cell Death Genes Reactome R-HSA-5633008
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release Reactome R-HSA-6803204
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain Reactome R-HSA-6803205
TP53 Regulates Transcription of Death Receptors and Ligands Reactome R-HSA-6803211
Regulation of TP53 Activity through Association with Co-factors Reactome R-HSA-6804759
RNA Polymerase II Transcription Reactome R-HSA-73857
Gene expression (Transcription) Reactome R-HSA-74160
Transcripts
Accession Version MolecularType Name NCBI Comments
XM_011544268 3 mRNA transcript variant X2 NC_000001 Reference
NM_001031685 3 mRNA transcript variant 1 NC_000001 Reference
NM_005426 3 mRNA transcript variant 2 NC_000001 Reference
XM_047429498 1 mRNA transcript variant X1 NC_000001 Reference
XM_011544269 3 mRNA transcript variant X3 NC_000001 Reference