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TYR

tyrosinase
General Information
Name tyrosinase
Alias
  • tyrosinase
  • LB24-AB
  • SK29-AB
  • monophenol monooxygenase
  • oculocutaneous albinism IA
  • tumor rejection antigen AB
Gene_family
organism Homo sapiens
entrez_id 7299
location 11q14.3
transcript_count 2
exon_count 6
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez The enzyme encoded by this gene catalyzes the first 2 steps, and at least 1 subsequent step, in the conversion of tyrosine to melanin. The enzyme has both tyrosine hydroxylase and dopa oxidase catalytic activities, and requires copper for function. Mutations in this gene result in oculocutaneous albinism, and nonpathologic polymorphisms result in skin pigmentation variation. The human genome contains a pseudogene similar to the 3' half of this gene. [provided by RefSeq, Oct 2008]
    Stringdb Tyrosinase; This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4- dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6- dihydroxyindole) to indole-5,6 quinone; Belongs to the tyrosinase family
    nextProt This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine (By similarity). In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone (PubMed:28661582).
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
TYR BioGRID Edem3 GeneID BioGRID Affinity Capture-Western
TYR BioGRID KRAS GeneID BioGRID Synthetic Lethality
TYR BioGRID PRKD2 GeneID BioGRID Affinity Capture-MS
TYR BioGRID SYVN1 GeneID BioGRID Affinity Capture-Western
TYR Protein TYRP1 GeneID HPRD
TYR Nucleotide RB1 GeneID BIND Rb interacts with the TYR promoter.
StringDB
A B experiments database textmining combined score hadb nhadb
TYR CSK 0 0 73 216 1 1
TYR FBXO11 0 0 113 208 1 1
TYR DPPA4 0 0 0 746 1 1
TYR SMARCB1 0 0 282 290 1 1
TYR MX2 0 0 218 218 1 1
TYR PRF1 0 0 287 286 1 1
TYR LPO 0 0 126 156 1 1
TYR TFF1 0 0 0 151 1 1
TYR DEFB113 0 0 0 200 1 1
TYR HBZ 0 0 0 539 1 1
TYR RAB36 0 0 66 204 1 1
TYR CALCA 0 0 147 166 1 1
TYR MUT 0 0 135 153 1 1
TYR HLA-DQA1 0 0 203 237 1 1
TYR BRAF 0 0 219 297 1 2
TYR BEST3 0 0 0 191 1 1
TYR RAB38 0 0 557 648 1 1
TYR ENO2 0 0 218 218 1 1
TYR VPS33A 0 0 108 187 1 1
TYR CENPF 0 0 74 181 1 1
TYR PTK2 0 0 181 181 1 2
TYR RAB6A 0 0 53 169 1 1
TYR DONSON 0 0 0 152 1 1
TYR MYLPF 0 0 0 167 1 1
TYR MC5R 0 0 178 276 1 1
TYR SKP2 0 0 0 181 1 2
TYR MAGEA3 0 0 739 779 1 2
TYR FAM172A 0 0 74 214 1 1
TYR HBG1 0 0 0 315 1 1
TYR ARG1 0 0 158 157 1 2
TYR EGF 0 0 293 293 1 2
TYR MAGEH1 0 0 295 295 1 1
TYR PROC 0 0 0 155 1 1
TYR BMP2 0 0 91 153 1 1
TYR RAB8B 0 0 0 169 1 2
TYR IGFBP1 0 0 0 678 1 1
TYR IL17A 0 0 202 202 1 2
TYR AKR1B1 0 0 210 210 1 1
TYR CRABP1 0 0 83 248 1 1
TYR HNF1A 0 0 108 203 1 1
TYR ETS1 0 0 143 179 1 1
TYR OR6B1 0 0 183 266 1 1
TYR POMC 0 0 560 644 1 1
TYR PAICS 0 0 45 282 1 1
TYR LIX1L 0 0 0 188 1 1
TYR CASP9 0 0 145 177 1 2
TYR NANOG 0 0 210 637 1 2
TYR TLR7 0 0 181 181 1 2
TYR CYCS 0 0 202 202 1 2
TYR MESP1 0 0 277 277 1 1
TYR DLG5 0 0 49 151 1 1
TYR MAGEA10 0 0 392 471 1 1
TYR BPTF 0 0 95 297 1 1
TYR NES 0 0 236 236 1 2
TYR HSPB3 0 0 136 198 1 1
TYR RDH5 0 0 266 311 1 1
TYR ACHE 0 0 468 468 1 2
TYR CXCL9 0 0 155 154 1 1
TYR TAT 0 900 108 907 1 2
TYR GNAS 0 0 90 201 1 1
TYR SLC8A3 0 0 166 275 1 1
TYR CYP1B1 0 0 350 354 1 1
TYR OR2M4 0 0 94 159 1 1
TYR HSPA4 0 0 298 298 1 1
TYR PMEL 0 0 878 976 1 1
TYR LIF 0 0 75 279 1 2
TYR MC1R 0 0 849 867 1 1
TYR CASP7 0 0 167 198 1 1
TYR MME 0 0 164 163 1 1
TYR COMMD1 0 0 170 170 1 1
TYR KRT71 0 0 108 262 1 1
TYR GALNTL6 0 0 110 200 1 1
TYR IDO1 0 0 202 202 1 1
TYR CLPTM1L 0 0 295 295 1 1
TYR SNAI2 0 0 326 325 1 1
TYR CD276 0 0 211 211 1 1
TYR CCL2 0 0 166 165 1 2
TYR CD68 0 0 240 239 1 2
TYR CASP8 0 0 211 240 1 2
TYR IQCF2 0 0 194 210 1 1
TYR ALB 0 0 414 606 1 2
TYR SERPINF1 0 0 259 262 1 1
TYR TNFRSF10A 0 0 325 325 1 1
TYR TICRR 0 0 0 156 1 1
TYR SERPINB1 0 0 194 199 1 1
TYR HPS3 0 0 561 589 1 1
TYR HNF1B 0 0 87 185 1 1
TYR AMBP 0 0 0 656 1 1
TYR VSX1 0 0 122 176 1 1
TYR PDGFRB 0 0 164 163 1 2
TYR LEF1 0 0 321 422 1 1
TYR EP300 0 0 120 159 1 2
TYR KCNJ13 0 0 167 167 1 1
TYR IL4 0 0 321 321 1 1
TYR OR8H3 0 0 161 161 1 1
TYR DDC 0 900 369 940 1 1
TYR CHRNA9 0 0 46 157 1 1
TYR TPTE 0 0 243 343 1 1
TYR RAB6C 0 0 0 159 1 1
TYR FZD8 0 0 112 307 1 1
TYR LEFTY2 0 0 46 158 1 1
TYR FRK 0 0 108 169 1 1
TYR PDPN 0 0 182 181 1 1
TYR CDH1 0 0 258 258 1 2
TYR GAGE2A 0 0 45 216 1 1
TYR IGF2BP1 0 0 96 289 1 1
TYR RAB32 0 0 455 479 1 2
TYR GLI2 0 0 171 171 1 2
TYR SLC24A2 0 0 150 208 1 1
TYR CRX 0 0 244 251 1 1
TYR CP 0 0 421 453 1 1
TYR CDK6 0 0 92 186 1 2
TYR ALDH3A2 0 0 0 250 1 1
TYR CHRM3 0 0 0 190 1 1
TYR SLC24A1 0 0 95 157 1 1
TYR IL1A 0 0 180 179 1 1
TYR HTR1A 0 0 98 150 1 1
TYR PCDH15 0 0 134 301 1 1
TYR SSX2 0 0 391 409 1 1
TYR C4BPB 0 0 0 204 1 1
TYR MFSD12 0 0 294 321 1 1
TYR ALK 0 0 135 171 1 2
TYR GAGE12D 0 0 0 282 1 1
TYR WNT1 0 0 193 194 1 2
TYR PAX6 0 0 296 296 1 1
TYR DRD2 0 0 145 330 1 1
TYR BCHE 0 0 468 536 1 1
TYR BSG 0 0 97 159 1 1
TYR DPP4 0 0 408 408 1 1
TYR MYOC 0 0 204 205 1 1
TYR PDE4A 0 0 285 285 1 1
TYR LIPI 0 0 112 173 1 1
TYR GTF3C2 0 0 57 158 1 1
TYR MAF 0 0 125 243 1 1
TYR LGALS4 0 0 146 189 1 1
TYR ATRN 0 0 224 358 1 1
TYR FOXD3 0 0 336 399 1 1
TYR ICAM1 0 0 241 240 1 2
TYR IGDCC3 0 0 0 191 1 1
TYR OCA2 0 0 865 959 1 1
TYR SOX9 0 0 286 296 1 1
TYR CTAG1B 0 0 681 681 1 1
TYR ZEB1 0 0 146 167 1 2
TYR PRSS3 0 0 163 163 1 1
TYR PTPRC 0 0 261 261 1 1
TYR SART1 0 0 141 165 1 1
TYR TRPT1 0 0 137 234 1 1
TYR HBE1 0 0 0 735 1 1
TYR GDF3 0 0 52 626 1 1
TYR ESR2 0 0 113 197 1 1
TYR ATRNL1 0 0 0 207 1 1
TYR LTBP2 0 0 61 161 1 1
TYR CYP2R1 0 0 67 522 1 1
TYR BEST4 0 0 0 199 1 1
TYR MTTP 0 0 0 256 1 1
TYR HIST1H1D 0 0 0 187 1 1
TYR DEF8 0 0 268 268 1 1
TYR GAGE1 0 0 195 262 1 1
TYR SLC25A48 0 0 93 250 1 1
TYR KLRK1 0 0 150 235 1 1
TYR CD3D 0 0 83 184 1 1
TYR AURKA 0 0 113 174 1 2
TYR CD1C 0 0 228 227 1 1
TYR GSR 0 0 122 162 1 1
TYR MAGEA6 0 0 390 475 1 1
TYR AR 0 0 125 229 1 2
TYR SOX8 0 0 105 160 1 1
TYR GDF10 0 0 66 160 1 1
TYR CDCA7 0 0 0 189 1 1
TYR EPCAM 0 0 163 163 1 2
TYR FXYD6 0 0 540 540 1 1
TYR CDKN1A 0 0 155 154 1 2
TYR SPP1 0 0 175 175 1 2
TYR CDHR1 0 0 305 305 1 1
TYR SPR 0 0 138 449 1 1
TYR VSX2 0 0 286 296 1 1
TYR OR51B5 0 0 0 153 1 1
TYR SLC11A2 0 0 144 177 1 1
TYR IGSF10 0 0 0 181 1 1
TYR MAPK3 0 0 267 283 1 2
TYR MMP9 0 0 217 234 1 2
TYR B2M 0 0 308 307 1 1
TYR PROM1 0 0 194 211 1 2
TYR GRAP2 0 0 0 187 1 1
TYR SLC7A3 0 0 0 155 1 1
TYR SELL 0 0 204 204 1 1
TYR BPIFB2 0 0 0 345 1 1
TYR CD8B 0 0 91 227 1 1
TYR ORM1 0 0 0 163 1 1
TYR GOT1 0 900 0 904 1 1
TYR EDEM2 0 0 160 212 1 1
TYR CD40 0 0 264 264 1 2
TYR ITGB7 0 0 0 343 1 1
TYR ALDH3A1 0 0 55 200 1 1
TYR ACTB 0 0 460 479 1 2
TYR INS 0 0 324 323 1 2
TYR SERPINA12 0 0 0 190 1 1
TYR NCAPG2 0 0 57 201 1 1
TYR AP3B2 0 0 0 202 1 1
TYR RAB29 0 0 54 199 1 1
TYR ABCA4 0 0 234 254 1 1
TYR PRSS1 0 0 180 227 1 1
TYR SOX2 0 0 261 325 1 2
TYR PDE6G 0 0 134 172 1 1
TYR KIF13A 0 0 285 296 1 1
TYR E2F7 0 0 67 184 1 1
TYR HPGDS 0 0 234 234 1 1
TYR BACE2 0 0 107 151 1 1
TYR CSAG1 0 0 74 168 1 1
TYR TFEB 0 0 181 279 1 2
TYR HSP90AA1 0 0 166 180 1 2
TYR HEPH 0 0 322 335 1 1
TYR JUN 0 0 271 271 1 2
TYR MGRN1 0 0 259 292 1 1
TYR UTS2 0 0 0 319 1 1
TYR PLCB4 0 0 123 202 1 1
TYR SLC45A1 0 0 0 189 1 1
TYR ITIH2 0 0 0 321 1 1
TYR CDH17 0 0 156 155 1 1
TYR SERPINB2 0 0 0 218 1 1
TYR SERPINA1 0 0 160 271 1 2
TYR SI 0 0 520 531 1 1
TYR CYP19A1 0 0 95 180 1 2
TYR ENSG00000173366 0 0 185 185 1 1
TYR COX17 0 0 256 256 1 1
TYR DSCAM 0 0 0 347 1 1
TYR NR2F2 0 0 120 176 1 1
TYR SLC8A2 0 0 0 167 1 1
TYR MPP4 0 0 0 154 1 1
TYR ERBB4 0 0 146 168 1 1
TYR HLA-DRB1 0 0 167 219 1 1
TYR ITIH3 0 0 0 330 1 1
TYR SLC8A1 0 0 151 262 1 1
TYR SNCA 0 0 471 543 1 2
TYR RERE 0 0 247 246 1 1
TYR DNTT 0 0 74 305 1 1
TYR CHEK1 0 0 101 233 1 2
TYR CD27 0 0 171 171 1 1
TYR CCNA2 0 0 113 235 1 1
TYR SCO1 0 0 202 271 1 1
TYR TK1 0 0 82 173 1 1
TYR TCF7 0 0 90 153 1 1
TYR KRT8 0 0 150 193 1 1
TYR MORN2 0 0 95 337 1 1
TYR IGF2BP3 0 0 0 252 1 1
TYR SLC47A1 0 0 0 203 1 1
TYR ORM2 0 0 0 245 1 1
TYR MMP2 0 0 211 247 1 2
TYR HAVCR2 0 0 181 181 1 1
TYR POLQ 0 0 0 154 1 1
TYR FAXC 0 0 0 179 1 1
TYR PSMB8 0 0 203 203 1 1
TYR RAB27A 0 0 663 724 1 1
TYR FANCA 0 0 96 196 1 1
TYR ERLEC1 0 0 113 168 1 1
TYR OTOS 0 0 95 291 1 1
TYR CALR 0 0 270 270 1 1
TYR CD8A 0 0 608 608 1 1
TYR SEPT4 0 0 561 561 1 1
TYR SOD1 0 0 170 189 1 2
TYR TBL1X 0 0 180 179 1 1
TYR FZD6 0 0 72 171 1 1
TYR CD69 0 0 212 240 1 1
TYR MNT 0 0 181 307 1 1
TYR SLC47A2 0 0 48 264 1 1
TYR LRAT 0 0 194 280 1 1
TYR CCR5 0 0 150 181 1 1
TYR KRT15 0 0 103 176 1 1
TYR SHH 0 0 293 364 1 2
TYR ARHGEF16 0 0 170 435 1 1
TYR ALX1 0 0 57 348 1 1
TYR LAMP3 0 0 160 159 1 1
TYR DCSTAMP 0 0 0 151 1 1
TYR PNMT 0 0 67 321 1 1
TYR CITED1 0 0 193 193 1 1
TYR TRPM6 0 0 45 151 1 1
TYR GRN 0 0 0 357 1 1
TYR MIA 0 0 402 423 1 2
TYR MSLN 0 0 218 220 1 1
TYR ARHGAP11A 0 0 0 177 1 1
TYR FST 0 0 54 268 1 1
TYR LAMP2 0 0 181 181 1 2
TYR SERPIND1 0 0 0 263 1 1
TYR GHRH 0 0 57 224 1 1
TYR RNF182 0 0 0 185 1 1
TYR ASIP 0 0 662 753 1 1
TYR JAG1 0 0 91 163 1 1
TYR LMAN2 0 0 55 260 1 1
TYR IFNG 0 0 310 371 1 2
TYR APC 0 0 67 155 1 1
TYR PASD1 0 0 216 619 1 1
TYR BAP1 0 0 205 205 1 1
TYR HLA-DQA2 0 0 134 171 1 1
TYR USP44 0 0 0 153 1 1
TYR CREB1 0 0 504 523 1 2
TYR GLRA3 0 0 0 215 1 1
TYR TDRD9 0 0 57 176 1 1
TYR SLC5A5 0 0 150 206 1 1
TYR POU3F2 0 0 270 381 1 1
TYR TPCN2 0 0 509 594 1 1
TYR CREBBP 0 0 112 150 1 1
TYR PSAP 0 0 119 208 1 1
TYR PTGER1 0 0 49 216 1 1
TYR TNFSF9 0 0 142 175 1 1
TYR CCNB1 0 0 142 202 1 1
TYR ANXA5 0 0 234 235 1 2
TYR MAGEA9 0 0 107 161 1 1
TYR RS1 0 0 146 169 1 1
TYR AP3B1 0 0 284 522 1 1
TYR CTAG2 0 0 255 254 1 1
TYR TRPC1 0 900 0 902 1 1
TYR SPECC1L 0 0 107 301 1 1
TYR SLC16A12 0 0 95 195 1 1
TYR BNC2 0 0 401 454 1 1
TYR TCHH 0 0 150 197 1 1
TYR DNMT3B 0 0 46 558 1 1
TYR MAGEE1 0 0 0 163 1 1
TYR BCL2L1 0 0 156 155 1 2
TYR ASGR2 0 0 0 241 1 1
TYR RAB40AL 0 0 105 179 1 1
TYR ALDH1A2 0 0 0 179 1 1
TYR WIF1 0 0 140 180 1 1
TYR SLC31A2 0 0 171 185 1 1
TYR KITLG 0 0 557 592 1 1
TYR BUB1 0 0 54 217 1 1
TYR CLNK 0 0 215 215 1 1
TYR CALCR 0 0 0 181 1 1
TYR TPO 0 900 140 915 1 1
TYR FANCB 0 0 0 188 1 1
TYR RHCE 0 0 49 213 1 1
TYR HOXB9 0 0 48 186 1 1
TYR HPS6 0 0 507 529 1 1
TYR ZIC1 0 0 108 171 1 1
TYR CD83 0 0 260 260 1 1
TYR APOA1 0 0 0 273 1 1
TYR NF1 0 0 283 282 1 1
TYR TAAR1 0 0 264 264 1 1
TYR MAP2K7 0 0 375 375 1 1
TYR NOS2 0 0 113 151 1 2
TYR CD1A 0 0 207 254 1 1
TYR CDK10 0 0 217 217 1 1
TYR TLR4 0 0 211 211 1 2
TYR APOBEC2 0 0 0 272 1 1
TYR CYP1A1 0 0 160 166 1 2
TYR CHD7 0 0 150 156 1 1
TYR GAPDH 0 0 451 464 1 2
TYR CHM 0 0 107 161 1 2
TYR CXCL8 0 0 270 270 1 2
TYR RAB6B 0 0 0 159 1 1
TYR KLK3 0 0 337 337 1 1
TYR SLC1A7 0 0 134 182 1 1
TYR ADAMTS20 0 0 167 480 1 1
TYR PRKCB 0 800 202 837 1 2
TYR HPS5 0 0 526 542 1 1
TYR TRPM7 0 0 90 191 1 1
TYR SH3BP4 0 0 96 205 1 1
TYR EDN1 0 0 400 445 1 1
TYR FZD4 0 0 144 202 1 1
TYR HIF1A 0 0 195 196 1 2
TYR MAGEC2 0 0 340 497 1 1
TYR EDEM3 0 0 143 287 1 1
TYR RAB5B 0 0 66 167 1 1
TYR IL1B 0 0 284 284 1 2
TYR RAD54L 0 0 66 159 1 1
TYR RAB5A 0 0 107 235 1 2
TYR PSAT1 0 0 0 154 1 1
TYR RHO 0 0 334 375 1 2
TYR HBG2 0 0 0 165 1 1
TYR PLA2G4A 0 0 0 258 1 1
TYR RAB17 0 0 137 212 1 1
TYR MYF5 0 0 86 182 1 1
TYR HRAS 0 0 459 462 1 2
TYR CTNNB1 0 0 454 454 1 2
TYR MAGED4B 0 0 653 653 1 1
TYR RHBG 0 0 74 228 1 1
TYR RDH10 0 0 206 227 1 1
TYR CDK2 0 0 293 379 1 2
TYR EPHA2 0 0 142 181 1 1
TYR APP 0 0 167 167 1 2
TYR GAGE12G 0 0 52 258 1 1
TYR NLRP1 0 0 181 181 1 1
TYR MTOR 0 0 147 155 1 2
TYR LAP3 0 0 43 189 1 1
TYR TRIB2 0 0 71 159 1 1
TYR MYO5A 0 0 524 558 1 1
TYR POTEF 0 0 134 165 1 1
TYR FAHD2B 0 0 0 204 1 1
TYR BLOC1S3 0 0 392 422 1 1
TYR FAM162B 0 0 123 171 1 1
TYR SMO 0 0 326 325 1 1
TYR NOC2L 0 0 0 207 1 1
TYR DR1 0 0 81 173 1 1
TYR CYR61 0 0 103 159 1 1
TYR CXCR4 0 0 202 217 1 2
TYR CTAG1A 0 0 681 681 1 1
TYR FGF13 0 0 170 189 1 1
TYR MMP1 0 0 194 230 1 1
TYR NOTCH1 0 0 260 275 1 2
TYR SCO2 0 0 112 152 1 1
TYR MPP1 0 0 0 154 1 1
TYR CD40LG 0 0 289 304 1 1
TYR PTGS1 0 0 150 160 1 1
TYR ARAF 0 0 161 179 1 1
TYR MORC1 0 0 436 453 1 1
TYR STAT1 0 0 171 171 1 2
TYR FOLR1 0 0 100 192 1 1
TYR TRIM37 0 0 0 154 1 1
TYR POU4F2 0 0 150 183 1 1
TYR ART1 0 0 321 321 1 1
TYR MYOG 0 0 74 171 1 1
TYR DCST2 0 0 108 350 1 1
TYR SLC45A4 0 0 108 245 1 1
TYR GZMB 0 0 307 307 1 1
TYR ALDH3B1 0 0 0 189 1 1
TYR TBX2 0 0 254 269 1 1
TYR SYVN1 270 0 67 289 1 1
TYR KCNMA1 0 0 63 208 1 1
TYR TFPI2 0 0 62 198 1 1
TYR MPZ 0 0 140 193 1 1
TYR TCF15 0 0 242 241 1 1
TYR ADAMTS16 0 0 0 156 1 1
TYR MPO 0 0 135 169 1 2
TYR VAT1 0 0 172 397 1 1
TYR LYVE1 0 0 161 161 1 1
TYR IL6 0 0 325 325 1 2
TYR MPP5 0 0 0 154 1 1
TYR BCO2 0 0 155 303 1 1
TYR SLC2A1 0 0 134 156 1 2
TYR LAMP1 0 0 391 390 1 2
TYR CDK4 0 0 420 420 1 2
TYR CCS 0 0 180 262 1 2
TYR EGFR 0 0 349 349 1 2
TYR CGA 0 0 46 248 1 2
TYR TNFRSF4 0 0 203 203 1 1
TYR MPP6 0 0 0 255 1 1
TYR MDM2 0 0 187 187 1 2
TYR TP53 0 0 503 510 1 2
TYR IRF9 0 0 0 161 1 1
TYR ERCC2 0 0 120 157 1 1
TYR MAOA 0 0 315 315 1 1
TYR SLC6A15 0 0 0 234 1 1
TYR S100A1 0 0 188 188 1 1
TYR AP3D1 0 0 166 199 1 1
TYR TAAR5 0 0 134 188 1 1
TYR HMBS 0 0 193 193 1 1
TYR LPP 0 0 180 179 1 1
TYR FGFR1OP 0 0 350 349 1 1
TYR PNLIP 0 0 193 196 1 1
TYR PAM 0 0 502 544 1 1
TYR PLP1 0 0 122 211 1 1
TYR FAHD2A 0 0 0 204 1 1
TYR TNFRSF11B 0 0 0 151 1 1
TYR KIF15 0 0 0 165 1 1
TYR QPCT 0 0 136 307 1 1
TYR GYG2 0 0 57 151 1 1
TYR RAF1 0 0 245 268 1 2
TYR EXO1 0 0 81 268 1 1
TYR LMNA 0 0 139 174 1 2
TYR ME2 0 0 0 254 1 1
TYR FGF7 0 0 184 183 1 1
TYR MPP7 0 0 0 154 1 1
TYR EDN3 0 0 504 554 1 1
TYR NTSR1 0 0 122 176 1 1
TYR CPB2 0 0 0 267 1 1
TYR MELK 0 0 74 166 1 1
TYR APRT 0 0 0 254 1 1
TYR ADCY1 0 0 142 182 1 1
TYR CACNA1F 0 0 113 318 1 1
TYR NKD1 0 0 0 154 1 1
TYR MAGEA2 0 0 424 490 1 1
TYR CDH2 0 0 218 282 1 1
TYR EXOC2 0 0 333 402 1 1
TYR HMCN1 0 0 124 168 1 1
TYR MREG 0 0 145 388 1 1
TYR CACNA1D 0 0 0 155 1 1
TYR MKKS 0 0 53 154 1 1
TYR PTPN22 0 0 261 261 1 1
TYR SLC14A2 0 0 54 157 1 1
TYR DEAF1 0 0 187 187 1 1
TYR EZH2 0 0 108 161 1 2
TYR STAT3 0 0 260 260 1 2
TYR IFNA2 0 0 213 213 1 1
TYR GAGE2E 0 0 0 213 1 1
TYR SLC13A5 0 0 0 257 1 1
TYR MTAP 0 0 539 544 1 1
TYR UGT2B10 0 0 0 226 1 1
TYR CHCHD6 0 0 0 189 1 1
TYR TM4SF5 0 0 248 360 1 1
TYR EDN2 0 0 172 598 1 1
TYR KRT5 0 0 194 199 1 1
TYR NF2 0 0 95 192 1 1
TYR NR2F1 0 0 134 189 1 1
TYR SERPINA11 0 0 0 195 1 1
TYR RAB8A 0 0 66 212 1 2
TYR CMSS1 0 0 81 285 1 1
TYR SCARB2 0 0 285 284 1 1
TYR USF1 0 0 270 480 1 1
TYR MPP3 0 0 0 154 1 1
TYR ABCC2 0 0 91 357 1 1
TYR SDHC 0 0 204 204 1 1
TYR IGF1R 0 0 163 163 1 2
TYR SLC18A2 0 0 450 450 1 1
TYR PPARGC1A 0 0 140 167 1 2
TYR MAGEA2B 0 0 415 457 1 1
TYR TPH1 0 0 150 165 1 1
TYR DGAT1 0 0 43 320 1 2
TYR APEX1 0 0 143 179 1 1
TYR PDK1 0 0 0 156 1 2
TYR IL15 0 0 267 267 1 1
TYR MYC 0 0 324 340 1 2
TYR SOX11 0 0 142 336 1 1
TYR UGT2A2 0 0 53 198 1 1
TYR KIF18A 0 0 0 155 1 1
TYR WNT5A 0 0 241 269 1 2
TYR IL18 0 0 145 164 1 2
TYR ABCB8 0 0 157 156 1 1
TYR IFNA1 0 0 324 323 1 1
TYR NR0B2 0 0 48 158 1 1
TYR PARK2 0 0 155 154 1 1
TYR FAHD1 0 0 0 370 1 1
TYR TSNAXIP1 0 0 170 169 1 1
TYR CEACAM5 0 0 391 390 1 1
TYR SERPINA5 0 0 51 166 1 1
TYR PIK3CA 0 0 98 154 1 2
TYR TFAP2B 0 0 96 152 1 1
TYR IL2RA 0 0 180 179 1 1
TYR AJAP1 0 0 0 264 1 1
TYR SOAT2 0 0 0 273 1 1
TYR MAGEB16 0 0 0 185 1 1
TYR NOG 0 0 115 178 1 1
TYR APOH 0 0 0 570 1 1
TYR NTS 0 0 52 677 1 1
TYR GNAQ 0 0 245 244 1 1
TYR CPN1 0 0 0 161 1 1
TYR XRCC3 0 0 74 168 1 1
TYR LAG3 0 0 215 215 1 1
TYR MLPH 0 0 560 630 1 1
TYR MYCN 0 0 113 150 1 1
TYR SUCO 0 0 92 191 1 1
TYR L1TD1 0 0 0 325 1 1
TYR PBK 0 0 83 218 1 1
TYR TFEC 0 0 431 501 1 1
TYR TDO2 0 0 408 408 1 1
TYR LGI3 0 0 143 377 1 1
TYR CD80 0 0 391 404 1 2
TYR CCL21 0 0 184 183 1 1
TYR BRCA1 0 0 161 228 1 2
TYR RPS17 0 0 123 158 1 1
TYR ASGR1 0 0 0 323 1 1
TYR C5 0 0 0 153 1 1
TYR TOP2A 0 0 86 158 1 1
TYR B4GALNT1 0 0 208 208 1 1
TYR MAP2K1 0 0 243 242 1 1
TYR GLRA2 0 0 0 207 1 1
TYR TDGF1 0 0 48 159 1 1
TYR VWCE 0 0 0 156 1 1
TYR TGFBR1 0 0 96 192 1 1
TYR MST1R 0 0 357 357 1 1
TYR CDC45 0 0 0 243 1 1
TYR RLBP1 0 0 459 515 1 1
TYR S100A4 0 0 291 290 1 1
TYR TERT 0 0 395 406 1 2
TYR HSPB2 0 0 62 192 1 1
TYR CASP16 0 0 52 155 1 1
TYR TYRP1 213 0 956 897 1 1
TYR MCAM 0 0 297 297 1 1
TYR CD1E 0 0 210 248 1 1
TYR LRP10 0 0 57 161 1 1
TYR TTK 0 0 112 183 1 1
TYR SLC24A5 0 0 757 916 1 1
TYR ADAM17 0 0 109 174 1 1
TYR SEL1L 0 0 142 169 1 1
TYR SOD3 0 0 166 184 1 1
TYR PIGQ 0 0 290 290 1 1
TYR ISM2 0 0 0 151 1 1
TYR VWDE 0 0 0 181 1 1
TYR RPS6KA1 0 0 162 161 1 1
TYR NCAM1 0 0 203 219 1 1
TYR SSX1 0 0 135 156 1 1
TYR CAMK2A 0 0 46 177 1 2
TYR ANO8 0 0 63 225 1 1
TYR GAL 0 0 0 181 1 1
TYR CCR7 0 0 288 288 1 1
TYR CCR9 0 0 0 151 1 1
TYR GALNT13 0 0 66 203 1 1
TYR WDR88 208 0 0 208 1 1
TYR BEST2 0 0 0 192 1 1
TYR MT-CO1 0 0 181 322 1 1
TYR KDM5B 0 0 171 171 1 1
TYR FN1 0 0 261 280 1 2
TYR MT-CYB 0 0 216 351 1 1
TYR AKT3 0 0 142 160 1 2
TYR PCBP3 0 0 57 189 1 1
TYR CTSB 0 0 134 152 1 2
TYR OFCC1 0 0 72 169 1 1
TYR RAB22A 0 0 95 239 1 1
TYR CHCHD3 0 0 108 419 1 1
TYR DLK1 0 0 57 263 1 1
TYR SMARCA4 0 0 181 181 1 1
TYR AIRE 0 0 259 258 1 1
TYR ITGAM 0 0 183 183 1 1
TYR PDCD1 0 0 234 235 1 2
TYR BACE1 0 0 165 185 1 2
TYR GNA11 0 0 254 254 1 1
TYR MPP2 0 0 0 154 1 1
TYR ADCY8 0 0 90 206 1 1
TYR ESR1 0 0 427 427 1 2
TYR RCVRN 0 0 154 153 1 1
TYR WNT3A 0 0 230 238 1 2
TYR CAMK2G 0 0 0 173 1 1
TYR SLC17A2 0 0 0 165 1 1
TYR MYO7A 0 0 389 388 1 1
TYR EDAR 0 0 217 230 1 1
TYR SYP 0 0 212 212 1 1
TYR MAGEA1 0 0 681 717 1 1
TYR GYPA 0 0 0 177 1 1
TYR XBP1 0 0 204 204 1 2
TYR HEMGN 0 0 0 315 1 1
TYR NECAP1 0 0 73 170 1 1
TYR CXCR3 0 0 184 183 1 1
TYR OTX2 0 0 370 398 1 1
TYR SRD5A2 0 0 61 162 1 1
TYR ATP4A 0 0 171 179 1 1
TYR ATOH7 0 0 142 236 1 1
TYR SLC6A3 0 0 112 167 1 1
TYR ELN 0 0 234 251 1 1
TYR TRIM51 0 0 0 181 1 1
TYR VEGFA 0 0 374 374 1 2
TYR IRF4 0 0 504 541 1 1
TYR MAGEA4 0 0 333 399 1 1
TYR BMPR1A 0 0 90 235 1 1
TYR PTEN 0 0 335 340 1 2
TYR RAB5C 0 0 48 151 1 1
TYR QDPR 0 0 181 270 1 1
TYR MYOD1 0 0 96 191 1 1
TYR PDCD1LG2 0 0 212 212 1 1
TYR PCBD2 0 0 66 275 1 1
TYR WT1 0 0 294 311 1 1
TYR ADAMTS7 0 0 0 156 1 1
TYR BMP4 0 0 180 181 1 1
TYR B3GALNT1 0 0 170 169 1 1
TYR KIT 0 0 562 592 1 2
TYR STEAP1 0 0 123 177 1 1
TYR ONECUT2 0 0 134 167 1 1
TYR PRAME 0 0 371 553 1 1
TYR FGB 0 0 0 151 1 1
TYR PRKG2 0 0 295 295 1 1
TYR ENSG00000258947 0 0 681 681 1 1
TYR TNFRSF9 0 0 268 268 1 1
TYR SIX6 0 0 151 349 1 1
TYR PRIM1 0 0 0 175 1 1
TYR GCHFR 0 0 92 340 1 1
TYR NGFR 0 0 339 343 1 1
TYR CD79A 0 0 0 208 1 1
TYR RAB27B 0 0 74 306 1 1
TYR NMU 0 0 0 261 1 1
TYR CTSD 0 0 156 174 1 2
TYR TRIM63 0 0 0 163 1 1
TYR ATP7B 0 0 391 484 1 1
TYR RAB41 0 0 0 159 1 1
TYR M6PR 0 0 343 343 1 1
TYR IGF2 0 0 134 180 1 1
TYR SERPINC1 0 0 49 220 1 1
TYR STX12 0 0 162 183 1 1
TYR ATM 0 0 209 209 1 2
TYR G6PD 0 0 134 194 1 1
TYR SOX10 0 0 660 743 1 1
TYR ENSG00000270386 0 0 54 199 1 1
TYR ARSJ 0 0 398 406 1 1
TYR RET 0 0 181 181 1 1
TYR C10orf11 0 0 560 560 1 1
TYR HLA-A 0 0 495 495 1 1
TYR GOT2 0 900 93 908 1 1
TYR NPTX1 0 0 0 315 1 1
TYR FCGR3B 0 0 153 152 1 1
TYR HPS1 0 0 243 259 1 1
TYR AGRP 0 0 114 343 1 1
TYR LALBA 0 0 195 195 1 1
TYR TF 0 0 0 317 1 2
TYR TJP1 0 0 212 212 1 1
TYR TGFBR2 0 0 107 172 1 1
TYR ACTG1 0 0 150 178 1 1
TYR GDF15 0 0 145 229 1 1
TYR PRAMEF4 0 0 0 181 1 1
TYR B4GALT1 0 0 293 293 1 1
TYR UBASH3A 0 0 294 294 1 1
TYR DBH 0 0 504 504 1 1
TYR HBB 0 0 329 329 1 1
TYR IL10 0 0 320 319 1 2
TYR SNAI1 0 0 171 171 1 1
TYR CXCR6 0 0 55 158 1 1
TYR GFAP 0 0 156 161 1 2
TYR ASPM 0 0 56 169 1 1
TYR FLT3 0 0 180 179 1 2
TYR RFESD 0 0 0 327 1 1
TYR ERCC5 0 0 139 157 1 1
TYR SLC35D3 0 0 95 260 1 1
TYR GPI 0 0 295 295 1 2
TYR PRODH2 0 0 0 157 1 1
TYR AHSG 0 0 0 682 1 1
TYR CDH23 0 0 150 208 1 1
TYR TG 0 0 170 169 1 1
TYR TBX15 0 0 91 169 1 1
TYR OR4S2 0 0 108 262 1 1
TYR HIST3H3 0 0 322 321 1 1
TYR DHFR 0 0 211 249 1 1
TYR TBC1D7 0 0 0 181 1 2
TYR WNT2 0 0 96 174 1 1
TYR ZIC2 0 0 112 174 1 1
TYR MEIOB 0 0 0 237 1 1
TYR USF2 0 0 61 174 1 1
TYR NTF3 0 0 270 270 1 1
TYR ELSPBP1 0 0 0 170 1 1
TYR MCHR2 0 0 415 414 1 1
TYR NLRP11 0 0 0 151 1 1
TYR DTL 0 0 0 173 1 1
TYR TRPM3 0 0 134 188 1 1
TYR EPHB2 0 0 66 160 1 2
TYR PI4K2A 0 0 50 194 1 1
TYR VAT1L 0 0 0 158 1 1
TYR CDKN2A 0 0 468 468 1 2
TYR SALL4 0 0 0 241 1 1
TYR ITGAX 0 0 232 231 1 1
TYR S100B 0 0 325 325 1 1
TYR TTR 0 0 150 247 1 1
TYR GSK3B 0 0 312 314 1 2
TYR TARBP1 0 0 152 151 1 1
TYR FOLH1 0 0 309 366 1 1
TYR MOK 0 0 181 181 1 1
TYR RAB20 0 0 0 165 1 1
TYR CD28 0 0 213 322 1 1
TYR TET1 0 0 0 183 1 1
TYR GGA3 0 0 73 172 1 1
TYR HIST1H1E 0 0 0 173 1 1
TYR MAL 0 0 0 303 1 1
TYR VEGFC 0 0 161 230 1 1
TYR GRM1 0 0 128 267 1 1
TYR SLC38A8 0 0 270 270 1 1
TYR EBF3 0 0 143 166 1 1
TYR UGT2A1 0 0 56 158 1 1
TYR OR5B17 0 0 172 258 1 1
TYR SLC25A40 0 0 98 160 1 1
TYR ACE 0 0 232 231 1 1
TYR NCAPG 0 0 63 200 1 1
TYR CD1B 0 0 204 288 1 1
TYR TMPRSS15 0 0 74 282 1 1
TYR AFP 0 0 270 801 1 2
TYR CENPN 0 0 0 151 1 1
TYR MT-ND2 0 0 150 298 1 1
TYR NQO1 0 0 161 181 1 2
TYR CASP3 0 0 291 317 1 2
TYR ERBB3 0 0 182 181 1 1
TYR PTGS2 0 0 288 296 1 2
TYR PSMB9 0 0 218 218 1 1
TYR SLC16A9 0 0 90 229 1 1
TYR LIX1 0 0 48 307 1 1
TYR CDCA2 0 0 55 150 1 1
TYR EGLN1 0 0 66 193 1 1
TYR OMP 0 0 351 368 1 1
TYR SLC4A3 0 0 0 254 1 1
TYR ACSM3 0 0 0 262 1 1
TYR PLA2G6 0 0 359 359 1 1
TYR OS9 0 0 142 233 1 1
TYR DSCR8 0 0 0 323 1 1
TYR ADCY3 0 0 150 292 1 1
TYR APBA2 0 0 180 185 1 1
TYR CDT1 0 0 0 175 1 1
TYR VHLL 0 0 0 189 1 1
TYR FOXC1 0 0 321 321 1 1
TYR CSPG4 0 0 363 475 1 1
TYR PDIA3 0 0 448 448 1 1
TYR FZD5 0 0 53 201 1 1
TYR BAGE5 0 0 556 556 1 1
TYR UNC93A 0 0 81 248 1 1
TYR DDX43 0 0 150 151 1 1
TYR CD86 0 0 325 325 1 1
TYR MCHR1 0 0 203 203 1 1
TYR FLT4 0 0 150 219 1 1
TYR DNAJC10 0 0 73 171 1 1
TYR SLC45A2 0 0 837 917 1 1
TYR HPS4 0 0 517 525 1 1
TYR KIAA2013 0 0 113 266 1 1
TYR MFI2 0 0 218 218 1 1
TYR AMH 0 0 0 173 1 1
TYR MET 0 0 229 228 1 2
TYR TMX4 0 0 75 173 1 1
TYR AP1S1 0 0 447 464 1 1
TYR MAOB 0 0 210 210 1 1
TYR EEF1G 274 0 0 274 1 1
TYR CAMK2B 0 0 0 173 1 1
TYR ABCB1 0 0 246 263 1 2
TYR ADCY10 0 0 147 155 1 1
TYR SUFU 0 0 108 171 1 1
TYR IL2 0 0 509 509 1 1
TYR NRL 0 0 162 206 1 1
TYR SERPINA7 0 0 0 459 1 1
TYR ASPSCR1 0 0 161 161 1 1
TYR DTNBP1 0 0 358 366 1 1
TYR ZIC3 0 0 54 189 1 1
TYR SNRNP200 0 0 67 161 1 1
TYR BBX 0 0 48 202 1 1
TYR PALMD 0 0 57 160 1 1
TYR KRAS 105 0 195 295 1 2
TYR GTSF1 0 0 0 331 1 1
TYR LAD1 0 0 67 178 1 1
TYR EPAS1 0 0 134 198 1 2
TYR DRAP1 0 0 55 252 1 1
TYR HLA-B 0 0 195 195 1 1
TYR GALNT1 0 0 49 188 1 1
TYR RP9 0 0 113 177 1 1
TYR NRAS 0 0 503 533 1 1
TYR CASP14 0 0 55 372 1 1
TYR TFE3 0 0 384 522 1 2
TYR ROM1 0 0 155 154 1 1
TYR SFMBT1 0 0 112 312 1 1
TYR FTH1 0 0 125 155 1 1
TYR SLC2A9 0 0 52 267 1 1
TYR BIRC7 0 0 235 308 1 1
TYR SCGB2A2 0 0 162 161 1 1
TYR FOXN1 0 0 164 346 1 1
TYR MAGED4 0 0 653 653 1 1
TYR FRMD7 0 0 234 234 1 1
TYR FAM189A1 0 0 113 249 1 1
TYR LMAN2L 0 0 0 250 1 1
TYR FASLG 0 0 181 181 1 1
TYR CRNN 0 0 69 278 1 1
TYR FOS 0 0 161 161 1 2
TYR NUP155 0 0 0 155 1 1
TYR CLEC9A 0 0 155 154 1 1
TYR FGL1 0 0 0 273 1 1
TYR MATK 0 0 0 189 1 1
TYR RHOD 0 0 112 212 1 1
TYR ANKRD32 0 0 0 264 1 1
TYR PRKAR1A 0 0 203 220 1 2
TYR SPTA1 0 0 0 554 1 1
TYR DHRS2 0 0 0 214 1 1
TYR GRM5 0 0 383 458 1 1
TYR AP1S2 0 0 167 184 1 1
TYR CLGN 0 0 0 197 1 1
TYR OPN3 0 0 150 187 1 1
TYR CD58 0 0 184 183 1 1
TYR APOA2 0 0 0 673 1 1
TYR RAB21 0 0 117 157 1 1
TYR SLC31A1 0 0 281 307 1 1
TYR PHGDH 0 0 113 169 1 1
TYR RALY 0 0 350 349 1 1
TYR EDNRB 0 0 517 617 1 1
TYR FGG 0 0 0 448 1 1
TYR USH2A 0 0 123 283 1 1
TYR CXCL10 0 0 171 171 1 2
TYR TYMS 0 0 81 175 1 1
TYR WDHD1 0 0 0 187 1 1
TYR ASPG 0 0 74 213 1 1
TYR GAS2 0 0 0 161 1 1
TYR AXL 0 0 225 230 1 2
TYR TLR9 0 0 184 183 1 2
TYR RPTN 0 0 0 363 1 1
TYR CD1D 0 0 206 206 1 1
TYR MGAM 0 0 530 541 1 1
TYR ITM2B 0 0 74 171 1 1
TYR CTCFL 0 0 0 325 1 1
TYR FOXQ1 0 0 309 309 1 1
TYR HAO1 0 0 211 211 1 1
TYR RNASET2 0 0 357 357 1 1
TYR NEIL3 0 0 0 211 1 1
TYR TH 0 900 459 943 1 2
TYR SSUH2 0 0 0 211 1 1
TYR ERBB2 0 0 417 416 1 2
TYR ARG2 0 0 182 181 1 1
TYR BCO1 0 0 48 157 1 1
TYR GJA5 0 0 53 217 1 1
TYR ENSG00000274276 0 0 124 184 1 1
TYR NGF 0 0 215 215 1 2
TYR PRDX3 0 0 77 178 1 1
TYR CD34 0 0 346 345 1 2
TYR FOXF2 0 0 0 164 1 1
TYR CPA1 0 0 140 150 1 1
TYR LY96 0 0 192 192 1 1
TYR CSF2 0 0 501 501 1 1
TYR MKI67 0 0 0 189 1 2
TYR LHX2 0 0 181 280 1 1
TYR ACKR1 0 0 90 181 1 1
TYR AKT1 0 0 394 407 1 2
TYR GIPC1 0 0 111 164 1 1
TYR PPARG 0 0 261 261 1 2
TYR CA9 0 0 113 217 1 1
TYR CD4 0 0 518 521 1 2
TYR ATF1 0 0 195 196 1 1
TYR VCAM1 0 0 150 176 1 1
TYR GNAL 0 0 0 211 1 1
TYR PRDM16 0 0 242 241 1 1
TYR MAGEA12 0 0 304 405 1 1
TYR KNTC1 0 0 0 181 1 1
TYR GSTM1 0 0 188 199 1 1
TYR KLF4 0 0 139 158 1 2
TYR FGFR1 0 0 124 178 1 1
TYR ARMC9 0 0 293 293 1 1
TYR ST3GAL6 0 0 0 266 1 1
TYR TMPRSS11D 0 0 246 246 1 1
TYR ATP7A 0 0 504 531 1 1
TYR PSMD5 0 0 134 289 1 1
TYR FABP2 0 0 143 176 1 1
TYR PRSS48 0 0 155 154 1 1
TYR PCOLCE2 0 0 0 155 1 1
TYR ING1 0 0 103 256 1 1
TYR NOX4 0 0 90 157 1 2
TYR SPANXC 0 0 95 188 1 1
TYR TAAR9 0 0 113 153 1 1
TYR TCHP 0 0 159 158 1 1
TYR PNP 0 0 91 184 1 1
TYR FGA 0 0 49 279 1 1
TYR FOXP3 0 0 321 321 1 2
TYR HMOX1 0 0 293 293 1 2
TYR MITF 0 0 870 930 1 2
TYR KDR 0 0 218 235 1 2
TYR IL4I1 0 900 47 901 1 1
TYR COX11 0 0 210 275 1 1
TYR HMMR 0 0 166 258 1 1
TYR HAS2 0 0 0 179 1 1
TYR LYST 0 0 504 516 1 1
TYR RAB11A 0 0 156 155 1 2
TYR GDA 0 0 0 228 1 1
TYR MC4R 0 0 150 281 1 1
TYR RAB28 0 0 96 302 1 1
TYR RAB7B 0 0 167 167 1 1
TYR MGAT5 0 0 255 274 1 1
TYR VAMP7 0 0 202 206 1 2
TYR TDRD12 0 0 0 256 1 1
TYR CYP2D6 0 0 126 186 1 1
TYR GPC3 0 0 96 296 1 1
TYR TRPV4 0 0 68 161 1 1
TYR HSD17B2 0 0 59 194 1 1
TYR GRM6 0 0 96 274 1 1
TYR ADCY4 0 0 134 156 1 1
TYR PCSK9 0 0 74 181 1 1
TYR SLC24A4 0 0 601 628 1 1
TYR CTXN2 0 0 141 371 1 1
TYR KIF5B 0 0 134 167 1 1
TYR MB 0 0 181 181 1 2
TYR IGHMBP2 0 0 0 181 1 1
TYR EEA1 0 0 155 156 1 2
TYR RAG1 0 0 303 560 1 1
TYR F2 0 0 53 532 1 1
TYR KRT73 0 0 0 207 1 1
TYR ADA 0 0 74 209 1 1
TYR SRC 0 0 242 255 1 2
TYR DKK1 0 0 171 217 1 1
TYR STAMBP 0 0 171 171 1 1
TYR BLOC1S6 0 0 407 407 1 1
TYR GAGE12C 0 0 0 280 1 1
TYR VHL 0 0 0 189 1 2
TYR FLT1 0 0 181 199 1 1
TYR RPE65 0 0 517 600 1 1
TYR TLR3 0 0 171 171 1 2
TYR CDKN3 0 0 92 151 1 1
TYR SYT3 0 0 68 167 1 1
TYR CAMK2D 0 0 0 173 1 1
TYR MIF 0 0 155 154 1 2
TYR EWSR1 0 0 162 161 1 1
TYR HNF4A 0 0 177 195 1 1
TYR ADAM23 0 0 0 325 1 1
TYR EIF2AK3 0 0 195 195 1 2
TYR TERF2IP 0 0 161 218 1 1
TYR ADAMTS18 0 0 0 156 1 1
TYR TRIML2 0 0 0 181 1 1
TYR COMT 0 0 245 244 1 1
TYR CDK1 0 0 90 179 1 2
TYR MUC1 0 0 325 326 1 1
TYR ETV6 0 0 62 159 1 1
TYR HIST2H2BE 0 0 160 159 1 1
TYR AHR 0 0 134 157 1 2
TYR ADAMTS12 0 0 0 156 1 1
TYR TSPAN10 0 0 210 210 1 1
TYR KCNA1 0 0 60 162 1 1
TYR SAG 0 0 181 198 1 1
TYR KRT20 0 0 81 207 1 1
TYR SKIV2L2 0 0 0 202 1 1
TYR LOX 0 0 457 481 1 2
TYR EDNRA 0 0 141 292 1 1
TYR NTRK1 0 0 249 248 1 1
TYR FGF5 0 0 119 280 1 1
TYR CD19 0 0 212 212 1 1
TYR GAGE12F 0 0 45 253 1 1
TYR SERPINE2 0 0 87 318 1 1
TYR ABCB5 0 0 423 463 1 1
TYR KXD1 0 0 150 203 1 1
TYR SEMA3A 0 0 60 158 1 1
TYR GPR143 312 0 662 776 1 1
TYR CD274 0 0 394 397 1 2
TYR CCND1 0 0 293 293 1 2
TYR CDH18 0 0 0 152 1 1
TYR CTLA4 0 0 468 471 1 2
TYR FAH 0 0 130 217 1 1
TYR SLC16A8 0 0 107 162 1 1
TYR PLCE1 0 0 438 438 1 1
TYR RAB34 0 0 0 150 1 1
TYR GBA 0 0 123 171 1 1
TYR NADSYN1 0 0 82 656 1 1
TYR SFMBT2 0 0 0 187 1 1
TYR LIN28A 0 0 136 378 1 1
TYR MLANA 0 0 872 970 1 1
TYR MDK 0 0 123 185 1 1
TYR ANHX 0 0 184 183 1 1
TYR ADCY2 0 0 193 213 1 1
TYR HPRT1 0 0 155 154 1 1
TYR KIF23 0 0 46 151 1 1
TYR DCST1 0 0 0 188 1 1
TYR GCH1 0 0 167 294 1 1
TYR HGF 0 0 210 210 1 2
TYR AOX1 0 0 0 188 1 1
TYR ENSG00000264813 0 0 181 181 1 1
TYR SASH1 0 0 74 215 1 1
TYR POU5F1 0 0 213 259 1 2
TYR HPD 0 0 119 174 1 1
TYR ABCG5 0 0 0 165 1 1
TYR OPRM1 0 0 107 152 1 1
TYR CANX 0 0 792 821 1 2
TYR CENPK 0 0 0 155 1 1
TYR CAT 0 0 372 372 1 2
TYR PECAM1 0 0 218 218 1 1
TYR HLA-DMA 0 0 170 171 1 1
TYR VPS11 0 0 323 323 1 1
TYR XDH 0 0 138 345 1 1
TYR PSMD6 0 0 0 153 1 1
TYR TNF 0 0 441 451 1 2
TYR RHAG 0 0 65 698 1 1
TYR ADAMTS9 0 0 0 232 1 1
TYR STRN3 0 0 134 230 1 1
TYR VDR 0 0 181 181 1 2
TYR SIX3 0 0 235 249 1 1
TYR HDC 0 0 85 177 1 1
TYR MMP3 0 0 101 172 1 1
TYR DKK3 0 0 181 192 1 1
TYR TSHR 0 0 147 169 1 1
TYR KLRC3 0 0 0 181 1 1
TYR ADCY6 0 0 123 164 1 1
TYR HERC2 0 0 214 338 1 1
TYR KRT14 0 0 195 200 1 1
TYR NT5E 0 0 74 221 1 1
TYR DCT 0 900 873 986 1 1
TYR IL7 0 0 244 243 1 1
TYR BDNF 0 0 155 173 1 2
TYR UBAC2 0 0 165 165 1 1
TYR CD44 0 0 247 246 1 2
TYR PNPLA6 0 0 213 213 1 1
TYR CNGA2 0 0 0 211 1 1
TYR MRPL28 0 0 520 520 1 1
TYR IFI30 0 0 218 231 1 1
TYR ERCC3 0 0 145 212 1 1
TYR IQCF1 0 0 125 189 1 1
TYR GAGE13 0 0 0 183 1 1
TYR TRPM1 0 0 523 625 1 1
TYR PAX3 0 0 599 643 1 1
TYR MAGEC1 0 0 210 441 1 1
TYR SLC7A11 0 0 156 344 1 2
TYR TPBG 0 0 245 244 1 1
TYR IKZF4 0 0 181 181 1 1
TYR AP3S1 0 0 181 181 1 1
TYR CBSL 0 0 124 227 1 1
TYR CENPH 0 0 0 214 1 1
TYR PAH 0 800 457 905 1 1
TYR ENSG00000249967 0 0 0 187 1 1
TYR MYL4 0 0 0 158 1 1
TYR NAGA 0 0 45 183 1 1
TYR GSTP1 0 0 163 163 1 1
TYR EDEM1 0 0 504 504 1 2
TYR APOC3 0 0 0 265 1 1
TYR PTCH1 0 0 169 191 1 1
TYR ATP12A 0 0 170 178 1 1
TYR SOX5 0 0 161 222 1 1
TYR FAM217A 0 0 162 161 1 1
TYR AGT 0 0 0 173 1 1
TYR CD70 0 0 297 297 1 1
TYR SPTSSB 0 0 0 693 1 1
TYR CD63 0 0 209 227 1 2
TYR RHOF 0 0 0 240 1 1
TYR TFAP2A 0 0 358 382 1 1
TYR MND1 0 0 0 237 1 1
TYR GOT1L1 0 900 0 903 1 1
TYR TFRC 0 0 234 369 1 1
TYR BCL2A1 0 0 156 155 1 1
TYR GPNMB 0 0 400 450 1 1
TYR RAB7A 0 0 181 181 1 2
TYR FGF2 0 0 362 362 1 2
TYR PCBD1 0 0 181 307 1 1
TYR C1QTNF6 0 0 324 323 1 1
TYR SLC25A25 0 0 219 224 1 1
TYR CASK 0 0 0 323 1 1
TYR CEP290 0 0 113 207 1 1
TYR MOCOS 0 0 57 177 1 1
TYR BEST1 0 0 459 536 1 1
TYR SLC4A2 0 0 70 394 1 1
TYR ANKRD27 0 0 284 298 1 1
TYR ATOX1 0 0 391 404 1 1
TYR LIPG 0 0 0 216 1 1
TYR MERTK 0 0 248 265 1 1
TYR FABP1 0 0 0 228 1 1
TYR BTK 0 0 113 157 1 1
TYR IGF1 0 0 202 202 1 2
TYR ASMT 0 0 94 232 1 1
TYR MAPK1 0 0 212 229 1 2
TYR DDX53 0 0 193 212 1 1
TYR APOB 0 0 81 598 1 2
TYR CSF1R 0 0 103 239 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0005507 Molecular Function copper ion binding enables IMP
GO:0042802 Molecular Function identical protein binding enables IDA
GO:0005515 Molecular Function protein binding enables IPI
GO:0042803 Molecular Function protein homodimerization activity enables ISS
GO:0004503 Molecular Function tyrosinase activity enables IBA
GO:0004503 Molecular Function tyrosinase activity enables IDA
GO:0008283 Biological Process cell population proliferation involved_in IEA
GO:0006726 Biological Process eye pigment biosynthetic process involved_in TAS
GO:0042438 Biological Process melanin biosynthetic process involved_in IBA
GO:0042438 Biological Process melanin biosynthetic process involved_in IDA
GO:0006583 Biological Process melanin biosynthetic process from tyrosine involved_in TAS
GO:0043473 Biological Process pigmentation involved_in IBA
GO:0009411 Biological Process response to UV involved_in IEA
GO:0009637 Biological Process response to blue light involved_in IDA
GO:0051591 Biological Process response to cAMP involved_in IEA
GO:0033280 Biological Process response to vitamin D involved_in IEA
GO:0048538 Biological Process thymus development involved_in IEA
GO:0007601 Biological Process visual perception involved_in TAS
GO:0005798 Cellular Component Golgi-associated vesicle located_in TAS
GO:0005737 Cellular Component cytoplasm located_in IDA
GO:0043231 Cellular Component intracellular membrane-bounded organelle located_in IDA
GO:0005764 Cellular Component lysosome located_in TAS
GO:0042470 Cellular Component melanosome located_in ISS
GO:0033162 Cellular Component melanosome membrane located_in TAS
GO:0048471 Cellular Component perinuclear region of cytoplasm located_in IDA
Pathways
Name DB ID
Metabolism Reactome R-HSA-1430728
Melanin biosynthesis Reactome R-HSA-5662702
Metabolism of amino acids and derivatives Reactome R-HSA-71291
GPR143 in melanocytes and retinal pigment epithelium cells (WP4941) WikiPathways WP4941_r120578
Dopamine metabolism (WP2436) WikiPathways WP2436_r107129
Prader-Willi and Angelman syndrome (WP3998) WikiPathways WP3998_r123316
Transcripts
Accession Version MolecularType Name NCBI Comments
XM_011542970 3 mRNA transcript variant X1 NC_000011 Reference
NM_000372 5 mRNA None NC_000011 Reference