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VHL

von Hippel-Lindau tumor suppressor
General Information
Name von Hippel-Lindau tumor suppressor
Alias
  • von Hippel-Lindau disease tumor suppressor
  • elongin binding protein
  • protein G7
  • von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
Gene_family
organism Homo sapiens
entrez_id 7428
location 3p25.3
transcript_count 4
exon_count 4
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez This gene encodes a component of a ubiquitination complex. The encoded protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF), which is a transcription factor that plays a central role in the regulation of gene expression by oxygen. In addition to oxygen-related gene expression, this protein plays a role in many other cellular processes including cilia formation, cytokine signaling, regulation of senescence, and formation of the extracellular matrix. Variants of this gene are associated with von Hippel-Lindau syndrome, pheochromocytoma, erythrocytosis, renal cell carcinoma, and cerebellar hemangioblastoma. [provided by RefSeq, Jun 2022]
    Stringdb Von Hippel-Lindau disease tumor suppressor; Involved in the ubiquitination and subsequent proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Seems to act as a target recruitment subunit in the E3 ubiquitin ligase complex and recruits hydroxylated hypoxia- inducible factor (HIF) under normoxic conditions. Involved in transcriptional repression through interaction with HIF1A, HIF1AN and histone deacetylases. Ubiquitinates, in an oxygen-responsive manner, ADRB2; Belongs to the VHL family
    nextProt Involved in the ubiquitination and subsequent proteasomal degradation via the von Hippel-Lindau ubiquitination complex. Seems to act as a target recruitment subunit in the E3 ubiquitin ligase complex and recruits hydroxylated hypoxia-inducible factor (HIF) under normoxic conditions. Involved in transcriptional repression through interaction with HIF1A, HIF1AN and histone deacetylases. Ubiquitinates, in an oxygen-responsive manner, ADRB2.
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
VHL BioGRID PIAS4 GeneID BioGRID Affinity Capture-Western; Co-localization; Reconstituted Complex
VHL BioGRID HIF1A GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity; Co-crystal Structure; Far Western; PCA; Protein-peptide; Reconstituted Complex; Two-hybrid
VHL BioGRID DVL2 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Co-localization; Protein-peptide
VHL BioGRID CUL2 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-purification; Reconstituted Complex; Two-hybrid
VHL BioGRID EPAS1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex; Two-hybrid
VHL BioGRID ORF1ab GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
VHL BioGRID ZHX2 GeneID BioGRID Affinity Capture-Western
VHL BioGRID YAP1 GeneID BioGRID Affinity Capture-Western
VHL BioGRID PAX2 GeneID BioGRID Reconstituted Complex
VHL BioGRID HERC5 GeneID BioGRID Affinity Capture-MS
VHL BioGRID FAM110C GeneID BioGRID Negative Genetic
VHL BioGRID ARMH1 GeneID BioGRID Negative Genetic
VHL BioGRID MCM9 GeneID BioGRID Negative Genetic
VHL BioGRID C6orf136 GeneID BioGRID Negative Genetic
VHL BioGRID PROM2 GeneID BioGRID Negative Genetic
VHL BioGRID SLC20A1 GeneID BioGRID Negative Genetic
VHL BioGRID TRA2B GeneID BioGRID Negative Genetic
VHL BioGRID SDHD GeneID BioGRID Negative Genetic
VHL BioGRID SDHB GeneID BioGRID Negative Genetic
VHL BioGRID CNOT4 GeneID BioGRID Negative Genetic
VHL BioGRID MYL6 GeneID BioGRID Negative Genetic
VHL BioGRID MSMB GeneID BioGRID Negative Genetic
VHL BioGRID MPV17 GeneID BioGRID Negative Genetic
VHL BioGRID MET GeneID BioGRID Negative Genetic
VHL BioGRID CAPRIN1 GeneID BioGRID Negative Genetic
VHL BioGRID KPNA4 GeneID BioGRID Negative Genetic
VHL BioGRID IL3 GeneID BioGRID Negative Genetic
VHL BioGRID IGFALS GeneID BioGRID Negative Genetic
VHL BioGRID PDIA3 GeneID BioGRID Negative Genetic; Two-hybrid
VHL BioGRID GAK GeneID BioGRID Negative Genetic
VHL BioGRID FANCG GeneID BioGRID Negative Genetic
VHL BioGRID FANCA GeneID BioGRID Negative Genetic
VHL BioGRID DIAPH2 GeneID BioGRID Negative Genetic
VHL BioGRID DHODH GeneID BioGRID Negative Genetic
VHL BioGRID DGUOK GeneID BioGRID Negative Genetic
VHL BioGRID BMPR1A GeneID BioGRID Negative Genetic
VHL BioGRID ADRA1A GeneID BioGRID Negative Genetic
VHL BioGRID ITLN2 GeneID BioGRID Negative Genetic
VHL BioGRID C1orf122 GeneID BioGRID Negative Genetic
VHL BioGRID MTFMT GeneID BioGRID Negative Genetic
VHL BioGRID SLC39A13 GeneID BioGRID Negative Genetic
VHL BioGRID SPOCD1 GeneID BioGRID Negative Genetic
VHL BioGRID SLC25A33 GeneID BioGRID Negative Genetic
VHL BioGRID BRIP1 GeneID BioGRID Negative Genetic
VHL BioGRID SHARPIN GeneID BioGRID Affinity Capture-Western; Negative Genetic
VHL BioGRID ATG9A GeneID BioGRID Negative Genetic
VHL BioGRID HROB GeneID BioGRID Negative Genetic
VHL BioGRID RHBDF1 GeneID BioGRID Negative Genetic
VHL BioGRID ATG101 GeneID BioGRID Negative Genetic
VHL BioGRID DHX35 GeneID BioGRID Negative Genetic
VHL BioGRID FASTKD5 GeneID BioGRID Negative Genetic
VHL BioGRID RPRD1B GeneID BioGRID Negative Genetic
VHL BioGRID CIP2A GeneID BioGRID Negative Genetic
VHL BioGRID BIRC6 GeneID BioGRID Negative Genetic
VHL BioGRID OTUB1 GeneID BioGRID Negative Genetic
VHL BioGRID PPP2R3C GeneID BioGRID Negative Genetic
VHL BioGRID TOR4A GeneID BioGRID Negative Genetic
VHL BioGRID GTPBP2 GeneID BioGRID Negative Genetic
VHL BioGRID MXRA8 GeneID BioGRID Negative Genetic
VHL BioGRID FBXO42 GeneID BioGRID Negative Genetic
VHL BioGRID CAB39 GeneID BioGRID Affinity Capture-MS; Negative Genetic
VHL BioGRID GTSE1 GeneID BioGRID Negative Genetic
VHL BioGRID GAL GeneID BioGRID Negative Genetic
VHL BioGRID PHPT1 GeneID BioGRID Negative Genetic
VHL BioGRID ZNF638 GeneID BioGRID Negative Genetic
VHL BioGRID FBXL4 GeneID BioGRID Negative Genetic
VHL BioGRID AAR2 GeneID BioGRID Negative Genetic
VHL BioGRID TPSG1 GeneID BioGRID Negative Genetic
VHL BioGRID WDR7 GeneID BioGRID Negative Genetic
VHL BioGRID FBXW11 GeneID BioGRID Negative Genetic
VHL BioGRID PDS5A GeneID BioGRID Negative Genetic
VHL BioGRID SLC4A1AP GeneID BioGRID Negative Genetic
VHL BioGRID RASL10A GeneID BioGRID Negative Genetic
VHL BioGRID RB1CC1 GeneID BioGRID Negative Genetic; Two-hybrid
VHL BioGRID PSMF1 GeneID BioGRID Negative Genetic
VHL BioGRID EIF4E2 GeneID BioGRID Negative Genetic
VHL BioGRID MMP23B GeneID BioGRID Negative Genetic
VHL BioGRID CUL3 GeneID BioGRID Affinity Capture-MS
VHL BioGRID RAD54L GeneID BioGRID Negative Genetic
VHL BioGRID WIPF1 GeneID BioGRID Negative Genetic
VHL BioGRID UMPS GeneID BioGRID Negative Genetic
VHL BioGRID UBE2H GeneID BioGRID Negative Genetic
VHL BioGRID PRKRA GeneID BioGRID Negative Genetic
VHL BioGRID MRPS9 GeneID BioGRID Two-hybrid
VHL BioGRID ANKEF1 GeneID BioGRID Two-hybrid
VHL BioGRID CPNE5 GeneID BioGRID Two-hybrid
VHL BioGRID BEX4 GeneID BioGRID Two-hybrid
VHL BioGRID NSUN5 GeneID BioGRID Two-hybrid
VHL BioGRID MAP1S GeneID BioGRID Two-hybrid
VHL BioGRID MSL2 GeneID BioGRID Two-hybrid
VHL BioGRID FBXO34 GeneID BioGRID Two-hybrid
VHL BioGRID AHI1 GeneID BioGRID Two-hybrid
VHL BioGRID ANKRD11 GeneID BioGRID Two-hybrid
VHL BioGRID BRCA1 GeneID BioGRID Negative Genetic; Two-hybrid
VHL BioGRID RERE GeneID BioGRID Two-hybrid
VHL BioGRID ZBTB17 GeneID BioGRID Two-hybrid
VHL BioGRID UBE2D2 GeneID BioGRID Reconstituted Complex; Two-hybrid
VHL BioGRID TTC3 GeneID BioGRID Two-hybrid
VHL BioGRID ELOC GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-crystal Structure; Co-purification; Reconstituted Complex; Two-hybrid
VHL BioGRID SPARC GeneID BioGRID Two-hybrid
VHL BioGRID SELENOP GeneID BioGRID Two-hybrid
VHL BioGRID NFKB2 GeneID BioGRID Affinity Capture-Western
VHL BioGRID COX2 GeneID BioGRID Two-hybrid
VHL BioGRID MAP1B GeneID BioGRID Two-hybrid
VHL BioGRID GUK1 GeneID BioGRID Two-hybrid
VHL BioGRID GTF3C2 GeneID BioGRID Two-hybrid
VHL BioGRID ETFA GeneID BioGRID Two-hybrid
VHL BioGRID EEF1A1 GeneID BioGRID Two-hybrid
VHL BioGRID KLHL10 GeneID BioGRID Two-hybrid
VHL BioGRID ZNF827 GeneID BioGRID Two-hybrid
VHL BioGRID COMMD1 GeneID BioGRID Two-hybrid
VHL BioGRID PIWIL4 GeneID BioGRID Two-hybrid
VHL BioGRID ERI1 GeneID BioGRID Two-hybrid
VHL BioGRID BEX2 GeneID BioGRID Two-hybrid
VHL BioGRID SPATA22 GeneID BioGRID Two-hybrid
VHL BioGRID SPZ1 GeneID BioGRID Two-hybrid
VHL BioGRID TEX35 GeneID BioGRID Two-hybrid
VHL BioGRID CDK5RAP3 GeneID BioGRID Two-hybrid
VHL BioGRID ITPKC GeneID BioGRID Two-hybrid
VHL BioGRID ZNF668 GeneID BioGRID Two-hybrid
VHL BioGRID NSUN7 GeneID BioGRID Two-hybrid
VHL BioGRID SUV39H2 GeneID BioGRID Two-hybrid
VHL BioGRID TDRD7 GeneID BioGRID Two-hybrid
VHL BioGRID FBXO28 GeneID BioGRID Two-hybrid
VHL BioGRID SMC5 GeneID BioGRID Two-hybrid
VHL BioGRID SNRNP200 GeneID BioGRID Two-hybrid
VHL BioGRID CCT5 GeneID BioGRID Affinity Capture-MS; Two-hybrid
VHL BioGRID PHB2 GeneID BioGRID Two-hybrid
VHL BioGRID NISCH GeneID BioGRID Two-hybrid
VHL BioGRID DIDO1 GeneID BioGRID Two-hybrid
VHL BioGRID DSTN GeneID BioGRID Two-hybrid
VHL BioGRID PPP1R13L GeneID BioGRID Affinity Capture-Western; Co-localization; Reconstituted Complex
VHL BioGRID STAMBP GeneID BioGRID Two-hybrid
VHL BioGRID CCT7 GeneID BioGRID Affinity Capture-MS; Two-hybrid
VHL BioGRID FLOT1 GeneID BioGRID Two-hybrid
VHL BioGRID ARHGEF7 GeneID BioGRID Two-hybrid
VHL BioGRID SAP30 GeneID BioGRID Two-hybrid
VHL BioGRID IFT88 GeneID BioGRID Two-hybrid
VHL BioGRID GPANK1 GeneID BioGRID Two-hybrid
VHL BioGRID ZNF200 GeneID BioGRID Two-hybrid
VHL BioGRID PSMC1 GeneID BioGRID Two-hybrid
VHL BioGRID PRKG1 GeneID BioGRID Two-hybrid
VHL BioGRID PKP2 GeneID BioGRID Two-hybrid
VHL BioGRID PFKP GeneID BioGRID Two-hybrid
VHL BioGRID ELOB GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-crystal Structure; Co-purification; Reconstituted Complex; Two-hybrid
VHL BioGRID RIT1 GeneID BioGRID Affinity Capture-Western; Negative Genetic
VHL BioGRID KRAS GeneID BioGRID Negative Genetic
VHL BioGRID EGFR GeneID BioGRID Negative Genetic
VHL BioGRID RBX1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-purification; Reconstituted Complex
VHL BioGRID MARVELD2 GeneID BioGRID Affinity Capture-Western
VHL BioGRID MTOR GeneID BioGRID Affinity Capture-Western
VHL BioGRID RPTOR GeneID BioGRID Affinity Capture-Western
VHL BioGRID APOBEC3B GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
VHL BioGRID APOBEC3G GeneID BioGRID Affinity Capture-Western
VHL BioGRID APOBEC3F GeneID BioGRID Affinity Capture-Western
VHL BioGRID APOBEC3A GeneID BioGRID Affinity Capture-Western
VHL BioGRID APOBEC3H GeneID BioGRID Affinity Capture-Western
VHL BioGRID JUP GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
VHL BioGRID BRD4 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity
VHL BioGRID VBP1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Two-hybrid
VHL BioGRID UTRN GeneID BioGRID Affinity Capture-MS
VHL BioGRID CCT3 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
VHL BioGRID TCP1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
VHL BioGRID CCT6A GeneID BioGRID Affinity Capture-MS
VHL BioGRID BMP2 GeneID BioGRID Affinity Capture-MS
VHL BioGRID AVP GeneID BioGRID Affinity Capture-MS
VHL BioGRID PFDN5 GeneID BioGRID Affinity Capture-MS
VHL BioGRID PFDN4 GeneID BioGRID Affinity Capture-MS
VHL BioGRID PFDN2 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
VHL BioGRID PFDN1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
VHL BioGRID OXT GeneID BioGRID Affinity Capture-MS
VHL BioGRID LAIR2 GeneID BioGRID Affinity Capture-MS
VHL BioGRID KNG1 GeneID BioGRID Affinity Capture-MS
VHL BioGRID ECM1 GeneID BioGRID Affinity Capture-MS
VHL BioGRID COMP GeneID BioGRID Affinity Capture-MS
VHL BioGRID COL9A1 GeneID BioGRID Affinity Capture-MS
VHL BioGRID CHIT1 GeneID BioGRID Affinity Capture-MS
VHL BioGRID EGFL7 GeneID BioGRID Affinity Capture-MS
VHL BioGRID TBK1 GeneID BioGRID Affinity Capture-Western; Protein-peptide; Reconstituted Complex
VHL BioGRID CCT8 GeneID BioGRID Affinity Capture-MS
VHL BioGRID CCT2 GeneID BioGRID Affinity Capture-MS
VHL BioGRID CCT4 GeneID BioGRID Affinity Capture-MS
VHL BioGRID CREB3 GeneID BioGRID Affinity Capture-MS
VHL BioGRID PFDN6 GeneID BioGRID Affinity Capture-MS
VHL BioGRID SFTPA2 GeneID BioGRID Affinity Capture-MS
VHL BioGRID ASTL GeneID BioGRID Affinity Capture-MS
VHL BioGRID ACTBL2 GeneID BioGRID Affinity Capture-MS
VHL BioGRID TAFA3 GeneID BioGRID Affinity Capture-MS
VHL BioGRID ARL14EP GeneID BioGRID Affinity Capture-MS
VHL BioGRID C1QTNF7 GeneID BioGRID Affinity Capture-MS
VHL BioGRID C1QTNF2 GeneID BioGRID Affinity Capture-MS
VHL BioGRID C1QTNF1 GeneID BioGRID Affinity Capture-MS
VHL BioGRID RETNLB GeneID BioGRID Affinity Capture-MS
VHL BioGRID KIRREL2 GeneID BioGRID Affinity Capture-MS
VHL BioGRID INHBE GeneID BioGRID Affinity Capture-MS
VHL BioGRID BCL2L14 GeneID BioGRID Affinity Capture-MS
VHL BioGRID ATF7IP GeneID BioGRID Affinity Capture-MS
VHL BioGRID SETDB1 GeneID BioGRID Affinity Capture-MS
VHL BioGRID ADIPOQ GeneID BioGRID Affinity Capture-MS
VHL BioGRID AR GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
VHL BioGRID PPARG GeneID BioGRID Affinity Capture-Western; Biochemical Activity
VHL BioGRID PPARD GeneID BioGRID Affinity Capture-Western
VHL BioGRID PPARA GeneID BioGRID Affinity Capture-Western
VHL BioGRID MDM2 GeneID BioGRID Affinity Capture-Western; Two-hybrid
VHL BioGRID UBE2D3 GeneID BioGRID Reconstituted Complex
VHL BioGRID TET3 GeneID BioGRID Affinity Capture-Western
VHL BioGRID TET2 GeneID BioGRID Affinity Capture-Western
VHL BioGRID USP39 GeneID BioGRID Affinity Capture-Western
VHL BioGRID HNRNPA2B1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-RNA; Affinity Capture-Western; Protein-RNA
VHL BioGRID OR6K3 GeneID BioGRID Affinity Capture-MS
VHL BioGRID SMURF1 GeneID BioGRID Affinity Capture-Western
VHL BioGRID OTUD6B GeneID BioGRID Affinity Capture-Western; Co-localization; Reconstituted Complex
VHL BioGRID UBE2S GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
VHL BioGRID WSB1 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
VHL BioGRID STAT3 GeneID BioGRID Affinity Capture-Western
VHL BioGRID JAK2 GeneID BioGRID Affinity Capture-Western
VHL BioGRID NR3C1 GeneID BioGRID Proximity Label-MS
VHL BioGRID CSTA GeneID BioGRID Affinity Capture-MS
VHL BioGRID ARNT GeneID BioGRID Affinity Capture-MS
VHL BioGRID S100A9 GeneID BioGRID Affinity Capture-MS
VHL BioGRID S100A8 GeneID BioGRID Affinity Capture-MS
VHL BioGRID POLR2I GeneID BioGRID Affinity Capture-MS
VHL BioGRID POLR2G GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex; Two-hybrid
VHL BioGRID POLR2D GeneID BioGRID Affinity Capture-MS
VHL BioGRID RWDD3 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
VHL BioGRID EPAS1 GeneID BioGRID Affinity Capture-Western
VHL BioGRID DIRAS2 GeneID BioGRID Affinity Capture-Western
VHL BioGRID TNFRSF1A GeneID BioGRID Negative Genetic
VHL BioGRID IFNL1 GeneID BioGRID Negative Genetic
VHL BioGRID IL22RA1 GeneID BioGRID Negative Genetic
VHL BioGRID MSH2 GeneID BioGRID Negative Genetic
VHL BioGRID HNRNPH1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-RNA
VHL BioGRID GPS1 GeneID BioGRID Reconstituted Complex
VHL BioGRID CCNC GeneID BioGRID Two-hybrid
VHL BioGRID HSF2BP GeneID BioGRID Two-hybrid
VHL BioGRID VHL GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity; Reconstituted Complex; Two-hybrid
VHL BioGRID CDKN1C GeneID BioGRID Affinity Capture-Western; Two-hybrid
VHL BioGRID CDKN1B GeneID BioGRID Affinity Capture-Western; Negative Genetic; Two-hybrid
VHL BioGRID CDKN1A GeneID BioGRID Affinity Capture-Western; Two-hybrid
VHL BioGRID G6PD GeneID BioGRID Affinity Capture-Western
VHL BioGRID GHET1 GeneID BioGRID Affinity Capture-RNA; Reconstituted Complex
VHL BioGRID H4C1 GeneID BioGRID Affinity Capture-MS
VHL BioGRID MAP1LC3B GeneID BioGRID Affinity Capture-Western; Co-localization; Reconstituted Complex
VHL BioGRID DCAF15 GeneID BioGRID Proximity Label-MS
VHL BioGRID NEK8 GeneID BioGRID Affinity Capture-Western
VHL BioGRID POLR2A GeneID BioGRID Affinity Capture-Western; Protein-peptide
VHL BioGRID TGFBR1 GeneID BioGRID Affinity Capture-Western; Co-localization
VHL BioGRID HSP42 GeneID BioGRID Affinity Capture-Western
VHL BioGRID SOCS1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
VHL BioGRID UBC GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
VHL BioGRID CASR GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
VHL BioGRID PPP5C GeneID BioGRID Affinity Capture-MS; Biochemical Activity
VHL BioGRID UBE2I GeneID BioGRID Biochemical Activity
VHL BioGRID FN1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
VHL BioGRID EAF2 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
VHL BioGRID ARIH1 GeneID BioGRID Affinity Capture-MS
VHL BioGRID MDFI GeneID BioGRID Two-hybrid
VHL BioGRID ITGB1 GeneID BioGRID Affinity Capture-Western
VHL BioGRID ITGA5 GeneID BioGRID Affinity Capture-Western
VHL BioGRID ITGA3 GeneID BioGRID Affinity Capture-Western
VHL BioGRID ITGA2 GeneID BioGRID Affinity Capture-Western
VHL BioGRID IKBKB GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
VHL BioGRID E6 GeneID BioGRID PCA
VHL BioGRID TXNIP GeneID BioGRID Affinity Capture-Western
VHL BioGRID COL4A2 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Far Western
VHL BioGRID COL4A1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
VHL BioGRID CDKN2A GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Two-hybrid
VHL BioGRID RPL6 GeneID BioGRID Affinity Capture-Western
VHL BioGRID PSMD2 GeneID BioGRID Affinity Capture-Western
VHL BioGRID HIF1AN GeneID BioGRID Reconstituted Complex
VHL BioGRID IL32 GeneID BioGRID Affinity Capture-Western
VHL BioGRID PRKCD GeneID BioGRID Affinity Capture-Western; FRET
VHL BioGRID FASN GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-localization
VHL BioGRID CAD GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
VHL BioGRID AKT1 GeneID BioGRID Affinity Capture-Western; Protein-peptide; Reconstituted Complex
VHL BioGRID Akt1 GeneID BioGRID Affinity Capture-Western
VHL BioGRID CEP68 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity
VHL BioGRID PPP2CA GeneID BioGRID Affinity Capture-Western
VHL BioGRID AURKA GeneID BioGRID Affinity Capture-Western; Biochemical Activity
VHL BioGRID AKT2 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
VHL BioGRID CER1 GeneID BioGRID Affinity Capture-MS
VHL BioGRID C1QB GeneID BioGRID Affinity Capture-MS
VHL BioGRID C1QL4 GeneID BioGRID Affinity Capture-MS
VHL BioGRID SQSTM1 GeneID BioGRID Affinity Capture-Western
VHL BioGRID PBRM1 GeneID BioGRID Negative Genetic
VHL BioGRID HUWE1 GeneID BioGRID Affinity Capture-Western
VHL BioGRID ARID1A GeneID BioGRID Negative Genetic
VHL BioGRID KDM5C GeneID BioGRID Negative Genetic
VHL BioGRID USP9X GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
VHL BioGRID VEGFA GeneID BioGRID Negative Genetic
VHL BioGRID TSC1 GeneID BioGRID Negative Genetic
VHL BioGRID HDAC2 GeneID BioGRID Affinity Capture-Western; Negative Genetic; Reconstituted Complex
VHL BioGRID FLT3 GeneID BioGRID Negative Genetic
VHL BioGRID FGFR3 GeneID BioGRID Negative Genetic
VHL BioGRID CHEK1 GeneID BioGRID Negative Genetic
VHL BioGRID SMARCB1 GeneID BioGRID Negative Genetic
VHL BioGRID RRM2 GeneID BioGRID Negative Genetic
VHL BioGRID RPS6KB1 GeneID BioGRID Negative Genetic
VHL BioGRID CDK6 GeneID BioGRID Negative Genetic
VHL BioGRID CDK4 GeneID BioGRID Negative Genetic
VHL BioGRID CASP8 GeneID BioGRID Negative Genetic
VHL BioGRID BRAF GeneID BioGRID Negative Genetic
VHL BioGRID ATM GeneID BioGRID Affinity Capture-Western; Negative Genetic
VHL BioGRID APC GeneID BioGRID Negative Genetic
VHL BioGRID ARID2 GeneID BioGRID Negative Genetic
VHL BioGRID PTEN GeneID BioGRID Negative Genetic
VHL BioGRID MAP2K1 GeneID BioGRID Negative Genetic
VHL BioGRID PRKDC GeneID BioGRID Negative Genetic
VHL BioGRID PIK3R1 GeneID BioGRID Negative Genetic
VHL BioGRID PDGFRA GeneID BioGRID Negative Genetic
VHL BioGRID ROR1 GeneID BioGRID Negative Genetic
VHL BioGRID MAP3K1 GeneID BioGRID Negative Genetic
VHL BioGRID HSP90AA1 GeneID BioGRID Affinity Capture-Western; Negative Genetic
VHL BioGRID EGLN1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
VHL BioGRID DACT1 GeneID BioGRID Affinity Capture-Western
VHL BioGRID RHOBTB3 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
VHL BioGRID CERKL GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
VHL BioGRID DACT2 GeneID BioGRID Affinity Capture-Western
VHL BioGRID EPOR GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
VHL BioGRID LIMD1 GeneID BioGRID Affinity Capture-Western
VHL BioGRID TARDBP GeneID BioGRID Affinity Capture-Western
VHL BioGRID PLD2 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
VHL BioGRID GPLD1 GeneID BioGRID Affinity Capture-Western
VHL BioGRID ID3 GeneID BioGRID Affinity Capture-Western
VHL BioGRID ID2 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
VHL BioGRID ID1 GeneID BioGRID Affinity Capture-Western
VHL BioGRID EP300 GeneID BioGRID Affinity Capture-Western
VHL BioGRID ZNF350 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
VHL BioGRID GOLGA4 GeneID BioGRID Affinity Capture-MS
VHL BioGRID TRIP12 GeneID BioGRID Affinity Capture-MS
VHL BioGRID NEDD8 GeneID BioGRID Affinity Capture-MS
VHL BioGRID PLD1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
VHL BioGRID ELC1 GeneID BioGRID Co-crystal Structure
VHL BioGRID TPT1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
VHL BioGRID USP33 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex; Two-hybrid
VHL BioGRID KAT2B GeneID BioGRID Affinity Capture-Western
VHL BioGRID E2F1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
VHL BioGRID HSPA4 GeneID BioGRID Affinity Capture-Western
VHL BioGRID GLI1 GeneID BioGRID Affinity Capture-Western
VHL BioGRID SIRT1 GeneID BioGRID Affinity Capture-Western
VHL BioGRID PARK7 GeneID BioGRID Affinity Capture-Western
VHL BioGRID PDCD5 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Two-hybrid
VHL BioGRID ILF3 GeneID BioGRID Affinity Capture-Western
VHL BioGRID HNRNPL GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
VHL BioGRID PRMT1 GeneID BioGRID Affinity Capture-Luminescence; Two-hybrid
VHL BioGRID PRMT8 GeneID BioGRID Two-hybrid
VHL BioGRID SON GeneID BioGRID Reconstituted Complex
VHL BioGRID SLC3A2 GeneID BioGRID Reconstituted Complex
VHL BioGRID SLC2A1 GeneID BioGRID Reconstituted Complex
VHL BioGRID RPS15A GeneID BioGRID Affinity Capture-MS; Reconstituted Complex
VHL BioGRID RPL21 GeneID BioGRID Reconstituted Complex
VHL BioGRID RPL5 GeneID BioGRID Reconstituted Complex
VHL BioGRID H4C16 GeneID BioGRID Reconstituted Complex
VHL BioGRID ACTB GeneID BioGRID Affinity Capture-MS; Reconstituted Complex
VHL BioGRID VAPB GeneID BioGRID Reconstituted Complex
VHL BioGRID H2BC13 GeneID BioGRID Reconstituted Complex
VHL BioGRID H1-2 GeneID BioGRID Reconstituted Complex
VHL BioGRID PRDX1 GeneID BioGRID Reconstituted Complex
VHL BioGRID NCL GeneID BioGRID Reconstituted Complex
VHL BioGRID HSPA8 GeneID BioGRID Affinity Capture-MS; Reconstituted Complex
VHL BioGRID HSPA5 GeneID BioGRID Reconstituted Complex
VHL BioGRID EEF1B2 GeneID BioGRID Reconstituted Complex
VHL BioGRID CD44 GeneID BioGRID Reconstituted Complex
VHL BioGRID CBR1 GeneID BioGRID Reconstituted Complex
VHL BioGRID CAPZB GeneID BioGRID Reconstituted Complex
VHL BioGRID CBX3 GeneID BioGRID Reconstituted Complex
VHL BioGRID RBPMS GeneID BioGRID Reconstituted Complex
VHL BioGRID CBX1 GeneID BioGRID Reconstituted Complex
VHL BioGRID LANCL1 GeneID BioGRID Reconstituted Complex
VHL BioGRID MSH4 GeneID BioGRID Affinity Capture-Western
VHL BioGRID NAM7 GeneID BioGRID Affinity Capture-Western
VHL BioGRID UXT GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
VHL BioGRID RPS6 GeneID BioGRID Affinity Capture-Western; Co-fractionation
VHL BioGRID RPS3A GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
VHL BioGRID RPS3 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-fractionation
VHL BioGRID RPL11 GeneID BioGRID Co-fractionation
VHL BioGRID NOB1 GeneID BioGRID Affinity Capture-Western; Co-fractionation
VHL BioGRID LTV1 GeneID BioGRID Affinity Capture-Western
VHL BioGRID KAT5 GeneID BioGRID Affinity Capture-Western
VHL BioGRID PCGF2 GeneID BioGRID Affinity Capture-Western
VHL BioGRID CHEK2 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
VHL BioGRID ZNF512B GeneID BioGRID Two-hybrid
VHL BioGRID DCUN1D1 GeneID BioGRID Affinity Capture-Western
VHL BioGRID FZR1 GeneID BioGRID Affinity Capture-Western
VHL BioGRID TGM2 GeneID BioGRID Affinity Capture-Western
VHL BioGRID SP1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
VHL BioGRID Cul2 GeneID BioGRID Affinity Capture-Western
VHL BioGRID Eloc GeneID BioGRID Affinity Capture-Western
VHL BioGRID Elob GeneID BioGRID Affinity Capture-Western
VHL BioGRID Rbx1 GeneID BioGRID Affinity Capture-Western
VHL BioGRID APP GeneID BioGRID Reconstituted Complex
VHL BioGRID CARD9 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
VHL BioGRID HNRNPD GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
VHL BioGRID MKNK2 GeneID BioGRID Affinity Capture-Western; Two-hybrid
VHL BioGRID CSNK2A1 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
VHL BioGRID CDC34 GeneID BioGRID Reconstituted Complex
VHL BioGRID ALAS1 GeneID BioGRID Affinity Capture-Western
VHL BioGRID RNF7 GeneID BioGRID Affinity Capture-Western
VHL BioGRID UBE2D1 GeneID BioGRID Reconstituted Complex
VHL BioGRID KLF4 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
VHL BioGRID TUBA1A GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
VHL BioGRID ELAVL1 GeneID BioGRID Affinity Capture-RNA; Affinity Capture-Western; Reconstituted Complex
VHL BioGRID PRKCZ GeneID BioGRID Affinity Capture-Western
VHL BioGRID HSPA1A GeneID BioGRID Co-fractionation
VHL BioGRID PARD3 GeneID BioGRID Affinity Capture-Western
VHL BioGRID PARD6A GeneID BioGRID Affinity Capture-Western
VHL BioGRID gag-pol GeneID BioGRID Affinity Capture-Western
VHL BioGRID YY1AP1 GeneID BioGRID Two-hybrid
VHL BioGRID FKBP8 GeneID BioGRID Two-hybrid
VHL BioGRID RBPMS2 GeneID BioGRID Two-hybrid
VHL BioGRID OSR1 GeneID BioGRID Affinity Capture-Western
VHL BioGRID SARNP GeneID BioGRID Two-hybrid
VHL BioGRID PRKCH GeneID BioGRID Affinity Capture-Western
VHL BioGRID CAPN7 GeneID BioGRID Two-hybrid
VHL BioGRID KIFAP3 GeneID BioGRID Affinity Capture-Western
VHL BioGRID EXOSC8 GeneID BioGRID Co-fractionation
VHL BioGRID KIF3A GeneID BioGRID Affinity Capture-Western; Two-hybrid
VHL BioGRID KIF2C GeneID BioGRID Two-hybrid
VHL BioGRID RACK1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
VHL BioGRID KIF3B GeneID BioGRID Affinity Capture-Western
VHL BioGRID DGKI GeneID BioGRID Affinity Capture-Western; Two-hybrid
VHL BioGRID PTPN14 GeneID BioGRID Affinity Capture-Western
VHL BioGRID COL4A3 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
VHL BioGRID CBX5 GeneID BioGRID Affinity Capture-Western
VHL BioGRID COPS5 GeneID BioGRID Affinity Capture-Western
VHL BioGRID BCL2L11 GeneID BioGRID Affinity Capture-Western
VHL BioGRID SOCS3 GeneID BioGRID Affinity Capture-Western
VHL BioGRID LPP GeneID BioGRID Affinity Capture-Western
VHL BioGRID AJUBA GeneID BioGRID Affinity Capture-Western
VHL BioGRID Elob GeneID BioGRID Reconstituted Complex
VHL BioGRID Eloc GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
VHL BioGRID HHV8GK18_gp81 GeneID BioGRID Biochemical Activity
VHL BioGRID WTIP GeneID BioGRID Affinity Capture-Western
VHL BioGRID ZYX GeneID BioGRID Affinity Capture-Western
VHL BioGRID SUMO1 GeneID BioGRID Affinity Capture-Western
VHL BioGRID TOP2A GeneID BioGRID Affinity Capture-Western
VHL BioGRID SIS1 GeneID BioGRID Affinity Capture-Western
VHL BioGRID BTN2 GeneID BioGRID Affinity Capture-Western
VHL BioGRID MYC GeneID BioGRID Affinity Capture-Western
VHL BioGRID HDAC1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
VHL BioGRID CLU GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
VHL BioGRID HNRNPA3 GeneID BioGRID Affinity Capture-MS
VHL BioGRID RALYL GeneID BioGRID Affinity Capture-MS
VHL BioGRID TUBA3D GeneID BioGRID Affinity Capture-MS
VHL BioGRID TUBA3E GeneID BioGRID Affinity Capture-MS
VHL BioGRID HNRNPLL GeneID BioGRID Affinity Capture-MS
VHL BioGRID ANKRD40 GeneID BioGRID Affinity Capture-MS
VHL BioGRID GRWD1 GeneID BioGRID Affinity Capture-MS
VHL BioGRID COLGALT1 GeneID BioGRID Affinity Capture-MS
VHL BioGRID FASTKD3 GeneID BioGRID Affinity Capture-MS
VHL BioGRID P3H1 GeneID BioGRID Affinity Capture-MS
VHL BioGRID CMC2 GeneID BioGRID Affinity Capture-MS
VHL BioGRID EIF5A2 GeneID BioGRID Affinity Capture-MS
VHL BioGRID NKRF GeneID BioGRID Affinity Capture-MS
VHL BioGRID UBR5 GeneID BioGRID Affinity Capture-MS
VHL BioGRID RPS27L GeneID BioGRID Affinity Capture-MS
VHL BioGRID STK38 GeneID BioGRID Affinity Capture-MS
VHL BioGRID TRAFD1 GeneID BioGRID Affinity Capture-MS
VHL BioGRID IVNS1ABP GeneID BioGRID Affinity Capture-MS
VHL BioGRID DDX17 GeneID BioGRID Affinity Capture-MS
VHL BioGRID CRTAP GeneID BioGRID Affinity Capture-MS
VHL BioGRID COL6A1 GeneID BioGRID Affinity Capture-MS
VHL BioGRID COL4A6 GeneID BioGRID Affinity Capture-MS
VHL BioGRID COL4A5 GeneID BioGRID Affinity Capture-MS
VHL BioGRID BSG GeneID BioGRID Affinity Capture-MS
VHL BioGRID PARP1 GeneID BioGRID Affinity Capture-MS
VHL BioGRID HNRNPDL GeneID BioGRID Affinity Capture-MS
VHL BioGRID DNAJA3 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
VHL BioGRID RPL14 GeneID BioGRID Affinity Capture-MS
VHL BioGRID PLOD3 GeneID BioGRID Affinity Capture-MS
VHL BioGRID DDX3Y GeneID BioGRID Affinity Capture-MS
VHL BioGRID XRCC5 GeneID BioGRID Affinity Capture-MS
VHL BioGRID TUBA3C GeneID BioGRID Affinity Capture-MS
VHL BioGRID TUBA4A GeneID BioGRID Affinity Capture-MS
VHL BioGRID TP53 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
VHL BioGRID SNRNP70 GeneID BioGRID Affinity Capture-MS
VHL BioGRID SKP2 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
VHL BioGRID RPS27 GeneID BioGRID Affinity Capture-MS
VHL BioGRID RPS17 GeneID BioGRID Affinity Capture-MS
VHL BioGRID RPS14 GeneID BioGRID Affinity Capture-MS
VHL BioGRID RPS11 GeneID BioGRID Affinity Capture-MS
VHL BioGRID RPS5 GeneID BioGRID Affinity Capture-MS
VHL BioGRID DNAJA2 GeneID BioGRID Affinity Capture-MS
VHL BioGRID STUB1 GeneID BioGRID Affinity Capture-MS
VHL BioGRID HNRNPR GeneID BioGRID Affinity Capture-MS
VHL BioGRID PRMT3 GeneID BioGRID Affinity Capture-Western
VHL BioGRID RPS2 GeneID BioGRID Affinity Capture-MS
VHL BioGRID RPLP0 GeneID BioGRID Affinity Capture-MS
VHL BioGRID RPL30 GeneID BioGRID Affinity Capture-MS
VHL BioGRID RPL18A GeneID BioGRID Affinity Capture-MS
VHL BioGRID RPL12 GeneID BioGRID Affinity Capture-MS
VHL BioGRID RPL7A GeneID BioGRID Affinity Capture-MS
VHL BioGRID RBBP7 GeneID BioGRID Affinity Capture-MS
VHL BioGRID RBBP4 GeneID BioGRID Affinity Capture-MS
VHL BioGRID PPM1B GeneID BioGRID Affinity Capture-MS
VHL BioGRID PLOD2 GeneID BioGRID Affinity Capture-MS
VHL BioGRID RPL10A GeneID BioGRID Affinity Capture-MS
VHL BioGRID HNRNPM GeneID BioGRID Affinity Capture-MS
VHL BioGRID MIF GeneID BioGRID Affinity Capture-MS
VHL BioGRID RPSA GeneID BioGRID Affinity Capture-MS
VHL BioGRID DNAJA1 GeneID BioGRID Affinity Capture-MS
VHL BioGRID HNRNPU GeneID BioGRID Affinity Capture-MS
VHL BioGRID HNRNPK GeneID BioGRID Affinity Capture-MS
VHL BioGRID HNRNPH2 GeneID BioGRID Affinity Capture-MS
VHL BioGRID HNRNPC GeneID BioGRID Affinity Capture-MS
VHL BioGRID HNRNPAB GeneID BioGRID Affinity Capture-MS
VHL BioGRID HNRNPA1 GeneID BioGRID Affinity Capture-MS
VHL BioGRID GRN GeneID BioGRID Affinity Capture-MS
VHL BioGRID EPHA4 GeneID BioGRID Affinity Capture-MS
VHL BioGRID EIF5A GeneID BioGRID Affinity Capture-MS
VHL BioGRID DDX5 GeneID BioGRID Affinity Capture-MS
VHL BioGRID DDX3X GeneID BioGRID Affinity Capture-MS
VHL BioGRID TUBB4B GeneID BioGRID Affinity Capture-MS
VHL BioGRID SPRY2 GeneID BioGRID Affinity Capture-Western
VHL BioGRID ADRB2 GeneID BioGRID Affinity Capture-Western
VHL BioGRID UBXN7 GeneID BioGRID Affinity Capture-MS
VHL BioGRID Myog GeneID BioGRID Affinity Capture-Western
VHL BioGRID MYBBP1A GeneID BioGRID Affinity Capture-MS; Far Western
VHL BioGRID PRKCI GeneID BioGRID Biochemical Activity
VHL BioGRID MCM7 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
VHL BioGRID HIF3A GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
VHL BioGRID USP20 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex; Two-hybrid
VHL BioGRID ELOA GeneID BioGRID Affinity Capture-Western
VHL BioGRID IREB2 GeneID BioGRID Affinity Capture-Western
VHL BioGRID JADE1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
VHL BioGRID CYBA GeneID BioGRID Affinity Capture-Western
VHL BioGRID SAT2 GeneID BioGRID Reconstituted Complex
VHL Protein HIF3A GeneID HPRD
VHL Protein POLR2G GeneID HPRD
VHL Protein ZNF197 GeneID HPRD
VHL Protein USP33 GeneID HPRD
VHL Protein JADE1 GeneID HPRD
VHL Protein HIF1AN GeneID HPRD
VHL Protein CCT3 GeneID HPRD
VHL Protein RBX1 GeneID HPRD
VHL Protein EPAS1 GeneID HPRD
VHL Protein CUL2 GeneID HPRD
VHL Protein HIF1A GeneID HPRD
VHL Protein RNF139 GeneID HPRD
VHL Protein ELOC GeneID HPRD
VHL Protein ELOB GeneID HPRD
VHL Protein HNRNPA2B1 GeneID HPRD
VHL Protein VBP1 GeneID HPRD
VHL Protein FLNA GeneID HPRD
VHL Protein SP1 GeneID HPRD
VHL Protein PSMC3 GeneID HPRD
VHL Protein FN1 GeneID HPRD
VHL BioGRID DGKZ GeneID BioGRID Affinity Capture-Western; Co-localization
VHL BioGRID SAP130 GeneID BioGRID Affinity Capture-Western
VHL BioGRID NR4A1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
VHL BioGRID CUL5 GeneID BioGRID Reconstituted Complex
VHL BioGRID HDAC3 GeneID BioGRID Reconstituted Complex
VHL BioGRID ZNF197 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
VHL BioGRID TRIM28 GeneID BioGRID Reconstituted Complex
VHL BioGRID PSMC3 GeneID BioGRID Affinity Capture-Western; Two-hybrid
VHL BioGRID STK16 GeneID BioGRID Affinity Capture-MS
VHL BioGRID TAGLN2 GeneID BioGRID Affinity Capture-MS
VHL BioGRID H2BC4 GeneID BioGRID Affinity Capture-MS
VHL BioGRID TXN GeneID BioGRID Affinity Capture-MS
VHL BioGRID TGFB1I1 GeneID BioGRID Affinity Capture-MS
VHL BioGRID TARS1 GeneID BioGRID Affinity Capture-MS
VHL BioGRID FSCN1 GeneID BioGRID Affinity Capture-MS
VHL BioGRID ATXN2 GeneID BioGRID Affinity Capture-MS
VHL BioGRID RPS9 GeneID BioGRID Affinity Capture-MS
VHL BioGRID RPA3 GeneID BioGRID Affinity Capture-MS
VHL BioGRID PSMD13 GeneID BioGRID Affinity Capture-MS
VHL BioGRID PSMB3 GeneID BioGRID Affinity Capture-MS
VHL BioGRID PSMB1 GeneID BioGRID Affinity Capture-MS
VHL BioGRID PPIB GeneID BioGRID Affinity Capture-MS
VHL BioGRID PIN1 GeneID BioGRID Affinity Capture-MS
VHL BioGRID PFAS GeneID BioGRID Affinity Capture-MS
VHL BioGRID PCMT1 GeneID BioGRID Affinity Capture-MS
VHL BioGRID MCC GeneID BioGRID Affinity Capture-MS
VHL BioGRID IMPDH2 GeneID BioGRID Affinity Capture-MS
VHL BioGRID IARS1 GeneID BioGRID Affinity Capture-MS
VHL BioGRID HAS1 GeneID BioGRID Affinity Capture-MS
VHL BioGRID CSTF3 GeneID BioGRID Affinity Capture-MS
VHL BioGRID CSTB GeneID BioGRID Affinity Capture-MS
VHL BioGRID CNTF GeneID BioGRID Affinity Capture-MS
VHL BioGRID CDO1 GeneID BioGRID Affinity Capture-MS
VHL BioGRID CDK2 GeneID BioGRID Affinity Capture-MS
VHL BioGRID RHOC GeneID BioGRID Affinity Capture-MS
VHL BioGRID APRT GeneID BioGRID Affinity Capture-MS
VHL BioGRID PKD1L3 GeneID BioGRID Affinity Capture-MS
VHL BioGRID JMJD1C GeneID BioGRID Affinity Capture-MS
VHL BioGRID RAB1B GeneID BioGRID Affinity Capture-MS
VHL BioGRID CCDC82 GeneID BioGRID Affinity Capture-MS
VHL BioGRID CCDC59 GeneID BioGRID Affinity Capture-MS
VHL BioGRID CHMP2B GeneID BioGRID Affinity Capture-MS
VHL BioGRID MOB4 GeneID BioGRID Affinity Capture-MS
VHL BioGRID MYL12A GeneID BioGRID Affinity Capture-MS
VHL BioGRID RASGRP1 GeneID BioGRID Affinity Capture-MS
VHL BioGRID KNTC1 GeneID BioGRID Affinity Capture-MS
VHL BioGRID PAPSS2 GeneID BioGRID Affinity Capture-MS
VHL BioGRID FLNA GeneID BioGRID Two-hybrid
VHL Protein HIF1A GeneID BIND HIF1A (HIF-1alpha) interacts with VHL.
VHL Protein USP33 GeneID BIND pVHL interacts with VDU1-type II.
VHL Protein EPAS1 GeneID BIND The von Hippel-Lindau tumor suppressor protein (pVHL) interacts with Hypoxia inducible factor-2-alpha (HIF-2 alpha)
VHL Protein JADE1 GeneID BIND The von Hippel-Lindau tumor suppressor protein (pVHL) interacts with Jade-1
VHL Protein VBP1 GeneID BIND The von Hippel-Lindau tumor suppressor protein (pVHL) interacts with VBP1.
VHL Protein FLNA GeneID BIND The von Hippel-Lindau tumor suppressor protein (pVHL) interacts with FLNA .
VHL None None None BIND Hydroxylated HIF-1 alpha interacts with VHL. This interaction was modeled on a demonstrated interaction between human hydroxylated HIF-1 alpha and an unspecified isoform of VHL from an unspecified species.
VHL Protein FN1 GeneID BIND pVHL interacts with fibronectin 1
VHL Protein HIF1A GeneID BIND The von Hippel-Lindau tumor suppressor protein (pVHL) interacts with Hypoxia inducible factor-alpha (HIF-1 alpha)
StringDB
A B experiments database textmining combined score hadb nhadb
VHL NFKBIA 0 0 183 183 1 2
VHL KIT 0 0 166 190 1 2
VHL GOLGA4 211 0 0 211 1 1
VHL TUBB3 0 0 384 472 1 1
VHL UBE2M 44 0 249 260 1 1
VHL C12orf5 0 0 171 171 1 1
VHL LDHA 0 0 415 430 1 2
VHL EXOSC8 270 0 0 270 1 1
VHL DDC 0 0 0 163 1 1
VHL NOTCH3 0 0 453 453 1 1
VHL CAPN7 192 0 0 192 1 1
VHL UBA52 0 600 0 600 1 1
VHL SARNP 192 0 0 192 1 1
VHL CSNK2A2 0 0 70 270 1 1
VHL AUP1 0 540 0 550 1 1
VHL PDGFRB 0 0 152 176 1 2
VHL ENSG00000258947 0 0 306 405 1 1
VHL KAT5 270 0 107 320 1 1
VHL PSMC3 270 0 571 673 1 1
VHL EP300 835 0 630 942 1 2
VHL CUL1 0 0 370 474 1 1
VHL ID3 270 0 0 270 1 1
VHL COMMD1 0 600 58 607 1 1
VHL NPAS1 0 0 0 320 1 1
VHL PTEN 128 0 392 488 1 2
VHL ELAVL1 485 0 261 603 1 2
VHL ITGB1 270 0 59 283 1 1
VHL SLC2A14 0 0 257 303 1 1
VHL DCAF7 0 0 149 237 1 1
VHL LRR1 0 0 292 497 1 1
VHL RABEP1 0 0 307 307 1 1
VHL VEGFA 176 900 681 971 1 2
VHL PGK1 0 0 374 374 1 2
VHL ILF3 270 0 117 327 1 1
VHL KDM5C 128 0 337 397 1 1
VHL NME8 0 0 0 179 1 1
VHL KNG1 195 0 43 196 1 1
VHL SDHA 0 0 252 252 1 1
VHL CASP8 128 0 90 172 1 2
VHL SENP8 0 0 280 289 1 1
VHL ALB 0 0 194 194 1 2
VHL TRAF7 0 0 0 175 1 1
VHL BHLHE41 0 0 160 159 1 1
VHL CUL5 270 0 492 700 1 1
VHL RPL21 270 0 0 270 1 1
VHL DGKI 270 0 66 289 1 1
VHL EGLN2 192 0 756 873 1 1
VHL DERL3 0 540 0 540 1 1
VHL COPS3 800 0 0 800 1 1
VHL FLT3 130 0 108 214 1 2
VHL RPS3A 294 0 0 294 1 1
VHL ZYX 270 0 0 270 1 1
VHL LGALS4 0 0 181 181 1 1
VHL UBE2S 631 0 373 758 1 1
VHL AANAT 0 0 0 151 1 1
VHL ZHX2 270 0 90 307 1 1
VHL SNAI1 0 0 235 235 1 1
VHL TCEB3 270 0 397 587 1 1
VHL SLC3A2 270 0 0 270 1 1
VHL GAD2 0 0 0 163 1 1
VHL CDH1 0 0 273 273 1 2
VHL PRKCZ 675 0 142 745 1 1
VHL ATM 431 0 677 828 1 2
VHL IDH1 0 0 308 307 1 1
VHL HIST1H1C 270 0 0 301 1 1
VHL RPL6 270 0 0 270 1 1
VHL IDH2 0 0 150 183 1 1
VHL IGF2 0 0 240 239 1 1
VHL NUB1 0 0 166 165 1 1
VHL PDGFRA 128 0 55 165 1 1
VHL SLC35E4 0 0 0 215 1 1
VHL SIRT6 0 0 205 210 1 2
VHL CDK6 130 0 150 229 1 2
VHL G6PD 270 0 82 301 1 1
VHL COMMD6 0 600 0 600 1 1
VHL ARSJ 0 0 306 306 1 1
VHL RET 0 0 259 280 1 1
VHL PLD1 270 0 0 270 1 2
VHL RBPMS 500 0 0 499 1 1
VHL DCUN1D2 0 600 0 600 1 1
VHL SETD2 0 0 340 344 1 1
VHL SEL1L 0 540 0 540 1 1
VHL RPL5 270 0 0 270 1 1
VHL CA12 0 0 414 414 1 1
VHL TRIM16L 0 0 0 175 1 1
VHL BRAF 128 0 0 152 1 2
VHL SKP2 270 0 432 613 1 2
VHL AKT3 0 0 91 204 1 2
VHL KDM5B 0 0 155 154 1 1
VHL CASR 270 0 0 270 1 2
VHL FN1 871 0 980 997 1 2
VHL SMARCB1 128 0 72 156 1 1
VHL CISH 0 0 265 276 1 1
VHL PAQR9 0 0 0 256 1 1
VHL RWDD3 270 0 405 547 1 1
VHL GLI1 270 0 123 342 1 2
VHL DCAF15 114 0 203 263 1 1
VHL TGFBR1 270 0 90 326 1 1
VHL SOCS6 0 0 124 186 1 1
VHL COL4A1 576 0 0 579 1 1
VHL S100A4 0 0 294 294 1 1
VHL IL22RA1 189 0 0 189 1 1
VHL HNRNPA2B1 675 0 425 805 1 1
VHL HIST2H3PS2 0 0 158 157 1 1
VHL ARID1A 176 0 48 182 1 1
VHL SESN2 0 0 287 286 1 2
VHL MAP1LC3B 270 0 113 332 1 2
VHL CSAD 0 0 0 163 1 1
VHL UBC 486 600 63 800 1 2
VHL SERPINB5 0 0 181 181 1 1
VHL TEK 0 0 196 219 1 1
VHL CBR1 270 0 0 270 1 1
VHL PIF1 0 0 0 294 1 1
VHL HIF1AN 486 0 771 877 1 1
VHL BCL2L14 272 0 0 272 1 1
VHL CACUL1 0 0 0 166 1 1
VHL ATG5 0 0 140 150 1 2
VHL RPTOR 0 0 167 167 1 2
VHL TYR 0 0 0 189 1 2
VHL PIK3R1 176 0 45 179 1 1
VHL EAF2 270 0 562 666 1 1
VHL CDKN1C 270 0 415 554 1 1
VHL MYBL2 0 0 194 194 1 1
VHL ASB3 118 0 144 226 1 1
VHL COMMD4 0 600 0 600 1 1
VHL C1QTNF2 206 0 0 206 1 1
VHL HSPA4 270 0 263 438 1 1
VHL NPAS3 0 0 0 320 1 1
VHL FASN 270 0 95 311 1 2
VHL SIRT1 270 0 241 462 1 2
VHL SMARCA4 800 0 125 817 1 1
VHL KIF3A 270 0 656 779 1 1
VHL EGF 0 0 263 263 1 2
VHL CBX1 270 0 0 270 1 1
VHL SENP1 0 0 204 217 1 1
VHL HNF1A 0 0 135 185 1 1
VHL NCL 270 0 46 273 1 2
VHL MSH2 189 0 57 202 1 1
VHL ESR1 0 0 214 227 1 2
VHL CHEK2 270 0 134 340 1 1
VHL CYCS 0 0 155 154 1 2
VHL DGKZ 270 0 0 270 1 1
VHL UBE2D2 270 600 113 723 1 1
VHL COPS5 892 0 261 923 1 1
VHL TUBB 0 0 0 185 1 1
VHL PSMC5 0 0 489 489 1 1
VHL MAP3K5 0 0 180 179 1 1
VHL FLCN 0 0 269 285 1 1
VHL HK1 0 0 161 161 1 1
VHL ACP2 0 0 0 173 1 1
VHL CAD 270 0 95 311 1 2
VHL CCDC22 0 600 0 600 1 1
VHL TCEB3B 103 0 0 193 1 1
VHL MET 0 0 282 302 1 2
VHL PRKCH 270 0 0 270 1 1
VHL FLT4 0 0 161 203 1 1
VHL HSPA1A 270 0 0 286 1 1
VHL KIF1B 0 0 213 226 1 1
VHL NCAPD2 0 0 0 218 1 1
VHL PMAIP1 0 0 146 158 1 2
VHL FMO5 0 0 0 190 1 1
VHL ITGA2 270 0 0 270 1 1
VHL RHBDD2 0 540 0 540 1 1
VHL SAP130 270 0 0 270 1 1
VHL MDFI 381 0 0 381 1 1
VHL DERL1 0 540 0 540 1 1
VHL IL2 0 0 166 165 1 1
VHL COX4I2 0 0 220 220 1 1
VHL BECN1 0 0 174 182 1 2
VHL SLC16A3 0 0 260 266 1 1
VHL ECT2L 0 0 0 175 1 1
VHL CHEK1 128 0 90 172 1 2
VHL RHOBTB3 270 600 54 729 1 1
VHL PSMD2 270 0 75 295 1 1
VHL PGF 0 0 207 208 1 1
VHL CCT6B 0 0 167 172 1 1
VHL JUN 0 0 231 230 1 2
VHL COL9A1 271 0 0 271 1 1
VHL USP20 270 0 524 660 1 1
VHL DNAJA3 294 0 152 376 1 1
VHL SLC16A4 0 0 220 221 1 1
VHL FMO4 0 0 134 188 1 1
VHL MSH4 270 0 0 270 1 1
VHL TSC1 176 0 184 298 1 2
VHL SEPSECS 0 0 0 360 1 1
VHL BCL2L11 270 0 113 324 1 2
VHL NEK8 270 0 217 404 1 1
VHL COPS6 800 0 0 800 1 1
VHL PRDX1 270 0 62 285 1 1
VHL UBE2F 0 0 163 163 1 1
VHL TCEB1 998 900 989 999 1 1
VHL AJUBA 270 600 0 695 1 1
VHL ARIH1 270 0 0 270 1 1
VHL ARNT 0 0 938 962 1 2
VHL NME4 94 0 0 224 1 1
VHL SOCS3 270 0 61 296 1 1
VHL ATF7IP 477 0 0 477 1 1
VHL COPS2 800 0 0 800 1 1
VHL MAX 0 0 144 168 1 2
VHL CCT7 294 0 54 303 1 1
VHL VBP1 854 0 709 962 1 1
VHL SOD2 0 0 162 161 1 2
VHL ENSG00000270024 0 0 53 152 1 1
VHL FZR1 270 0 0 270 1 1
VHL COMMD5 0 600 0 600 1 1
VHL FBXW10 0 0 0 175 1 1
VHL SEL1L2 0 540 0 540 1 1
VHL MMP2 0 0 225 224 1 2
VHL RPS15A 294 0 0 294 1 1
VHL SAT1 0 0 95 218 1 1
VHL ANGPT2 0 0 208 208 1 1
VHL FOXO1 0 0 123 156 1 2
VHL KRAS 0 0 201 237 1 2
VHL NEDD9 0 0 202 203 1 1
VHL EPAS1 989 900 692 999 1 2
VHL LANCL1 270 0 0 270 1 1
VHL BTRC 0 0 424 432 1 1
VHL ARL14EP 483 0 0 483 1 1
VHL E2F1 270 0 95 311 1 2
VHL HSPA5 270 0 71 292 1 2
VHL IGFBP3 0 0 151 150 1 2
VHL HIST1H2BL 270 0 0 284 1 1
VHL ENSG00000251537 0 0 0 175 1 1
VHL TARDBP 288 0 0 288 1 2
VHL CUL3 0 0 277 391 1 2
VHL CITED2 0 0 234 234 1 1
VHL UNC119 0 0 167 192 1 1
VHL AURKA 486 0 698 838 1 2
VHL ZYG11B 0 0 381 504 1 1
VHL KIFAP3 270 0 0 343 1 1
VHL CXCL12 0 0 215 215 1 2
VHL CDKN1A 270 0 203 393 1 2
VHL CDC34 270 0 194 386 1 1
VHL PBRM1 176 0 454 531 1 1
VHL GSK3B 0 0 149 235 1 2
VHL HNRNPH1 294 0 0 294 1 1
VHL TUBG1 0 0 306 376 1 1
VHL RPS27A 0 600 0 600 1 1
VHL USP33 486 540 614 905 1 1
VHL ADM 0 0 166 172 1 2
VHL HSPA8 294 0 82 324 1 2
VHL NOB1 270 0 0 270 1 1
VHL CDKN2A 499 0 480 728 1 2
VHL AR 486 0 140 546 1 2
VHL SOCS2 103 0 167 233 1 1
VHL SIRT7 0 0 204 209 1 2
VHL RRM2 128 0 81 164 1 1
VHL ACO1 0 0 241 252 1 1
VHL MXI1 0 0 229 255 1 1
VHL COPS4 800 0 0 800 1 1
VHL AKAP1 0 0 148 164 1 1
VHL HDAC1 486 0 218 583 1 2
VHL COPS7B 800 0 0 800 1 1
VHL EIF3E 0 0 176 175 1 1
VHL IGDCC3 0 0 102 346 1 1
VHL PHC3 0 0 0 303 1 1
VHL BCL10 0 0 89 202 1 1
VHL WTIP 270 600 0 695 1 1
VHL SART1 0 0 413 413 1 1
VHL NDRG3 0 0 480 480 1 1
VHL ZER1 0 0 265 646 1 1
VHL COMMD2 0 600 0 600 1 1
VHL SAT2 270 0 538 725 1 1
VHL JADE1 692 0 903 969 1 1
VHL TUBE1 0 0 0 169 1 1
VHL CASP3 0 0 181 181 1 2
VHL TUBB2B 0 0 0 185 1 1
VHL SMURF1 270 0 128 353 1 1
VHL PTGS2 0 0 147 165 1 2
VHL SGPL1 0 0 45 167 1 1
VHL CCP110 0 0 170 169 1 1
VHL COX4I1 0 0 168 167 1 1
VHL TUBB6 0 0 0 169 1 1
VHL HSP90AA1 439 0 405 658 1 2
VHL OS9 0 540 306 667 1 1
VHL UFD1L 0 0 113 306 1 1
VHL HPGDS 0 0 157 156 1 1
VHL PLD2 270 0 0 270 1 1
VHL EGLN1 677 600 889 990 1 1
VHL HNRNPL 294 0 145 370 1 1
VHL FBXW7 0 0 212 384 1 2
VHL COPS8 800 0 49 801 1 1
VHL MAPK3 0 0 203 220 1 2
VHL KEAP1 0 0 195 200 1 2
VHL MMP9 0 0 181 181 1 2
VHL GLO1 0 0 326 325 1 1
VHL ANGPT1 0 0 166 165 1 1
VHL SIRT3 0 0 181 186 1 2
VHL NME2 0 0 0 249 1 1
VHL CUL4A 0 0 210 315 1 1
VHL KLHL20 0 0 143 175 1 1
VHL SIM2 0 0 43 321 1 1
VHL HIST1H1E 0 0 0 181 1 1
VHL BNIP3 0 0 459 514 1 2
VHL SQSTM1 270 0 70 292 1 2
VHL VEGFC 0 0 149 164 1 1
VHL CERKL 270 0 113 324 1 1
VHL ACTB 294 0 392 561 1 2
VHL INS 0 0 270 270 1 2
VHL KLHL12 99 0 188 237 1 1
VHL KIF2A 0 0 90 387 1 1
VHL STUB1 41 0 218 218 1 2
VHL C1QB 271 0 0 271 1 1
VHL ADORA2B 0 0 139 156 1 1
VHL BNIP3L 0 0 270 298 1 2
VHL KIRREL2 297 0 0 297 1 1
VHL DDB1 0 0 165 165 1 1
VHL TSC2 0 0 308 333 1 2
VHL KIF3B 270 0 0 348 1 1
VHL RBX1 972 900 937 999 1 1
VHL NME7 0 0 0 179 1 1
VHL HRAS 0 0 242 264 1 2
VHL USP7 0 0 155 170 1 1
VHL CTNNB1 270 0 484 622 1 2
VHL KIF24 0 0 113 205 1 1
VHL SOCS7 0 0 94 165 1 1
VHL CDKN1B 439 0 160 508 1 2
VHL PRKCD 651 0 692 888 1 2
VHL DCAF11 0 0 162 181 1 1
VHL MDH2 0 0 150 168 1 1
VHL ZNF350 270 0 107 330 1 1
VHL IL32 270 0 0 270 1 1
VHL ING4 0 0 357 357 1 1
VHL PAX2 0 0 117 154 1 1
VHL HMOX1 0 0 194 205 1 2
VHL TUBB2A 0 0 0 185 1 1
VHL SELENBP1 0 0 243 242 1 1
VHL VCX3A 0 0 0 171 1 1
VHL ID1 270 0 81 300 1 1
VHL SUMO2 0 0 193 229 1 1
VHL TCHP 0 0 782 782 1 1
VHL ASTL 282 0 0 282 1 1
VHL CXCL8 0 0 160 159 1 2
VHL CEP68 486 0 0 485 1 1
VHL NDRG1 0 0 202 202 1 1
VHL SP1 486 0 183 568 1 2
VHL HIF3A 270 600 278 837 1 1
VHL IL1B 0 0 157 156 1 2
VHL UBA3 0 0 230 243 1 1
VHL RPL11 270 0 0 270 1 1
VHL NAE1 0 0 234 234 1 1
VHL CCT5 294 0 0 294 1 1
VHL PIAS4 676 900 107 971 1 1
VHL RSU1 0 0 51 297 1 1
VHL SKP1 0 0 406 418 1 2
VHL COMMD3 0 600 0 608 1 1
VHL EIF2S1 0 0 134 210 1 2
VHL USP1 0 0 728 733 1 1
VHL SIRT5 0 0 184 214 1 1
VHL HIF1A 998 900 989 999 1 2
VHL EDN1 0 0 218 218 1 1
VHL KDR 0 0 321 355 1 2
VHL NDUFA4L2 0 0 190 190 1 1
VHL ENSG00000115239 0 0 144 159 1 1
VHL TNFRSF1A 189 0 67 210 1 1
VHL RPS6 270 0 95 323 1 2
VHL TUBB8 0 0 0 185 1 1
VHL TRIM28 270 0 43 287 1 2
VHL ATG3 0 540 0 540 1 2
VHL DNAJB1 0 0 134 259 1 2
VHL SYVN1 0 540 0 573 1 1
VHL UBE2A 0 900 0 901 1 1
VHL FBXW9 0 0 0 175 1 1
VHL DACT2 270 0 0 270 1 1
VHL P4HTM 0 0 248 262 1 1
VHL SOCS5 0 0 81 173 1 1
VHL DNAJC28 0 0 0 224 1 1
VHL CBX3 270 0 0 270 1 1
VHL SIM1 0 0 45 323 1 1
VHL FLT1 0 0 294 329 1 1
VHL MYEOV2 0 0 141 194 1 1
VHL RNF139 270 0 0 371 1 1
VHL EIF2AK3 0 0 138 153 1 2
VHL IL6 0 0 181 181 1 2
VHL FMO2 0 0 202 410 1 1
VHL GAD1 0 0 0 163 1 1
VHL ACLY 43 0 140 160 1 1
VHL CER1 272 0 0 272 1 1
VHL TUBB8B 0 0 0 185 1 1
VHL COMMD10 0 600 0 611 1 1
VHL CCT3 461 0 43 462 1 1
VHL PSMC6 0 0 396 396 1 1
VHL THOC1 192 0 0 192 1 1
VHL USP2 0 0 691 691 1 1
VHL MTOR 0 0 425 424 1 2
VHL FOXO3 0 0 180 342 1 2
VHL HILPDA 0 0 181 181 1 1
VHL KDM4B 0 0 155 154 1 1
VHL KDM6A 0 0 243 242 1 1
VHL SLC2A4 0 0 139 192 1 1
VHL PDCD5 290 0 54 299 1 1
VHL OXT 483 0 0 483 1 1
VHL SIAH3 0 0 0 213 1 1
VHL SRC 0 0 247 274 1 2
VHL NOTCH1 0 0 250 250 1 2
VHL EEF1B2 270 0 0 270 1 1
VHL SATL1 0 0 0 171 1 1
VHL USP8 0 0 181 181 1 1
VHL SMURF2 0 0 150 172 1 1
VHL CDC42 0 0 123 169 1 2
VHL HIST1H4F 270 0 54 279 1 1
VHL CXCR4 0 0 309 314 1 2
VHL PLK1 0 0 122 161 1 2
VHL SIAH1 0 0 291 321 1 1
VHL MAP3K1 176 0 50 183 1 1
VHL EPO 0 0 610 628 1 2
VHL SPRTN 0 0 66 229 1 1
VHL SIRT2 0 0 218 231 1 2
VHL CUL7 0 0 159 158 1 1
VHL TRIP12 226 0 0 225 1 1
VHL NME1-NME2 0 0 0 249 1 1
VHL ERBB2 0 0 213 226 1 2
VHL RPS3 294 0 410 565 1 1
VHL ENSG00000274276 0 0 83 215 1 1
VHL NME5 0 0 0 179 1 1
VHL FOXF2 0 0 0 168 1 1
VHL PSMC1 0 0 437 437 1 1
VHL POLR2A 696 0 512 845 1 1
VHL ANXA5 0 0 161 161 1 2
VHL COMMD9 0 600 0 600 1 1
VHL GPLD1 270 0 0 270 1 1
VHL LMAN1 94 0 500 545 1 1
VHL DCUN1D5 0 600 0 600 1 1
VHL ID2 270 0 0 270 1 1
VHL USP9X 270 0 135 341 1 1
VHL PHGDH 0 0 155 154 1 1
VHL CREB1 0 0 155 154 1 2
VHL TCEB2 998 900 989 999 1 1
VHL WWP1 0 0 137 178 1 1
VHL TUBB1 0 0 0 169 1 1
VHL APC 176 0 86 214 1 1
VHL LTV1 270 0 0 270 1 1
VHL SIRT4 0 0 185 190 1 1
VHL TADA1 0 0 0 190 1 1
VHL BAP1 0 0 241 240 1 1
VHL ALAS1 270 0 0 275 1 1
VHL P4HA1 0 0 150 208 1 1
VHL SMC4 0 0 0 189 1 1
VHL CREBBP 0 0 248 417 1 1
VHL FOXO4 0 0 156 188 1 1
VHL PFKFB3 0 0 251 254 1 2
VHL RNF7 270 0 439 681 1 1
VHL EIF4EBP1 0 0 244 246 1 2
VHL UBE2D3 48 600 74 623 1 1
VHL SDHB 0 0 335 364 1 1
VHL COL4A2 567 0 0 570 1 1
VHL NF1 0 0 245 261 1 1
VHL HIST4H4 270 0 54 279 1 1
VHL WSB1 103 0 369 409 1 1
VHL AQR 0 0 74 326 1 1
VHL DACT1 270 0 81 300 1 1
VHL MAP2K7 0 0 181 181 1 1
VHL HUS1 0 0 61 552 1 1
VHL IKBKB 270 0 180 402 1 2
VHL HAMP 0 0 134 157 1 1
VHL KLF4 270 0 118 339 1 2
VHL TPT1 293 0 0 306 1 1
VHL GPS1 847 0 0 847 1 1
VHL FKBP8 192 0 108 248 1 1
VHL SDHD 0 0 400 472 1 1
VHL GAPDH 0 0 302 302 1 2
VHL NOX4 0 0 257 257 1 2
VHL COL4A3 294 0 0 294 1 1
VHL ENO1 0 0 217 217 1 1
VHL RUNX2 0 0 123 160 1 2
VHL BCL2L1 800 0 166 826 1 2
VHL AKT1 270 0 451 647 1 2
VHL PPARG 0 0 140 154 1 2
VHL VCX2 0 0 0 171 1 1
VHL TUBB4A 0 0 56 197 1 1
VHL MARCH6 0 540 0 540 1 1
VHL ALDOA 0 0 210 210 1 1
VHL VCX3B 0 0 0 171 1 1
VHL P4HA2 0 0 95 157 1 1
VHL SUMO1 270 800 203 890 1 1
VHL ATF4 0 0 162 161 1 2
VHL PTPN14 270 0 0 270 1 1
VHL CA9 0 0 608 619 1 1
VHL DERL2 0 540 0 540 1 1
VHL KITLG 0 0 154 153 1 1
VHL ISCU 0 0 184 201 1 1
VHL UQCRFS1 94 0 134 241 1 1
VHL NR4A3 213 0 0 213 1 1
VHL HCRTR1 0 0 397 396 1 1
VHL UBXN7 270 600 71 705 1 1
VHL NME1 0 0 44 251 1 1
VHL ROR1 128 0 0 152 1 1
VHL NME6 0 0 0 179 1 1
VHL YY1AP1 192 0 0 192 1 1
VHL TMEM127 0 0 206 206 1 1
VHL CBSL 0 0 83 215 1 1
VHL EGLN3 192 600 710 917 1 1
VHL OSR1 675 0 0 680 1 1
VHL TPX2 0 0 425 425 1 1
VHL ITCH 0 0 112 154 1 1
VHL RIT1 270 0 0 282 1 1
VHL PPARGC1A 0 0 161 161 1 2
VHL TNF 0 0 193 194 1 2
VHL SDHAF2 0 0 325 363 1 1
VHL HNRNPD 294 0 113 347 1 1
VHL UBE2D1 270 600 150 735 1 1
VHL KIF2C 192 0 0 327 1 1
VHL TUBB4B 41 0 0 185 1 1
VHL VPS11 0 0 0 258 1 1
VHL SDHC 0 0 334 360 1 1
VHL AKAP6 0 0 184 183 1 1
VHL IGF1R 0 0 184 261 1 2
VHL VAPB 270 0 0 270 1 1
VHL DIRC2 0 0 710 728 1 1
VHL CBX5 270 0 0 270 1 1
VHL CD44 270 0 74 295 1 2
VHL IFNA1 0 0 151 150 1 1
VHL CDRT1 0 0 0 175 1 1
VHL PPP5C 270 0 0 270 1 1
VHL KDM3A 0 0 181 181 1 1
VHL HDC 0 0 0 163 1 1
VHL POLR2G 270 0 323 484 1 1
VHL NR4A2 213 0 0 213 1 1
VHL PDK1 0 0 457 464 1 2
VHL MYC 270 0 599 698 1 2
VHL MYBBP1A 297 0 184 401 1 1
VHL PPRC1 0 0 181 181 1 1
VHL ARNT2 0 0 346 599 1 1
VHL PKM 0 0 283 282 1 1
VHL PCGF2 270 0 0 271 1 1
VHL FBXW2 0 0 0 175 1 1
VHL IFNL1 189 0 0 189 1 1
VHL TOP2A 270 0 0 270 1 1
VHL MAP2K1 130 0 123 223 1 1
VHL STK11 0 0 193 208 1 2
VHL PFKM 0 0 218 218 1 1
VHL PDGFB 0 0 241 240 1 2
VHL BRCA1 189 0 230 348 1 2
VHL PARD6A 270 0 55 352 1 1
VHL TMEM141 0 0 188 197 1 1
VHL IGF1 0 0 233 232 1 2
VHL ITGA3 270 0 0 270 1 2
VHL AKT2 270 0 144 427 1 2
VHL UVRAG 0 0 60 204 1 2
VHL UBE2K 0 0 438 464 1 1
VHL SOCS4 0 0 171 183 1 1
VHL FBXO16 0 0 0 175 1 1
VHL FBXW8 0 0 0 175 1 1
VHL RB1CC1 192 0 0 192 1 2
VHL SOCS1 482 0 92 517 1 1
VHL CEP97 0 0 134 156 1 1
VHL PIFO 0 0 139 157 1 1
VHL FXN 0 0 113 192 1 1
VHL SPRY2 270 0 753 812 1 1
VHL PARK7 270 0 0 289 1 2
VHL CUL4B 0 0 124 263 1 1
VHL TCP1 675 0 368 786 1 1
VHL CAPZB 270 0 0 270 1 1
VHL HIST1H1A 0 0 0 190 1 1
VHL PARD3 270 0 45 351 1 1
VHL IREB2 270 0 156 366 1 1
VHL EIF5B 0 0 773 773 1 1
VHL FBXO24 0 0 0 175 1 1
VHL FGF2 0 0 195 229 1 2
VHL VCX 0 0 0 171 1 1
VHL MKNK2 270 0 0 270 1 1
VHL SMAD4 0 0 445 445 1 2
VHL FLNA 469 0 70 485 1 1
VHL HDAC3 270 0 61 285 1 2
VHL CSNK2A1 486 0 0 521 1 1
VHL SMC5 0 0 0 190 1 1
VHL SLC2A3 0 0 290 334 1 1
VHL SUCO 0 0 330 330 1 1
VHL TXNIP 270 0 836 888 1 2
VHL LPP 270 0 0 270 1 1
VHL UBE2I 270 900 171 938 1 1
VHL NME3 0 0 0 179 1 1
VHL HDAC2 626 0 142 667 1 1
VHL DVL2 487 0 477 720 1 2
VHL CUL2 998 900 989 999 1 1
VHL CARD9 270 0 292 461 1 1
VHL SIAH2 0 0 391 417 1 1
VHL DCUN1D4 0 600 0 600 1 1
VHL BRK1 0 0 70 170 1 1
VHL CCND1 0 0 372 372 1 2
VHL HK2 0 0 240 239 1 2
VHL NOS3 0 0 218 218 1 2
VHL COMMD7 0 600 0 600 1 1
VHL RBPMS2 192 0 0 192 1 1
VHL RPS6KB1 128 0 242 337 1 2
VHL CDK4 128 0 123 203 1 2
VHL EGFR 0 0 310 321 1 2
VHL ZYG11A 0 0 345 451 1 1
VHL KAT2B 486 0 96 515 1 1
VHL ADRB2 270 0 195 475 1 1
VHL EIF4E 0 0 206 206 1 2
VHL SON 270 0 0 270 1 2
VHL FGFR3 128 0 0 153 1 1
VHL WDR86 0 0 0 175 1 1
VHL GADL1 0 0 0 163 1 1
VHL CRBN 0 0 195 268 1 1
VHL NEDD8 852 600 457 966 1 2
VHL SLC2A1 270 0 561 686 1 2
VHL DCUN1D1 270 600 113 718 1 1
VHL PPP2CA 270 0 0 270 1 1
VHL PRKDC 128 0 66 150 1 2
VHL AHR 0 0 252 252 1 2
VHL SERPINE1 0 0 243 242 1 1
VHL NTRK1 0 0 138 162 1 1
VHL EPOR 270 0 459 593 1 1
VHL COMMD8 0 600 0 600 1 1
VHL CBL 0 0 167 167 1 1
VHL PRMT8 43 0 0 150 1 1
VHL MDM2 0 0 414 414 1 2
VHL TP53 294 0 914 941 1 2
VHL PRKCI 270 0 0 405 1 1
VHL PCOLCE 0 0 0 303 1 1
VHL TGM2 270 0 55 280 1 2
VHL UXT 270 0 0 270 1 1
VHL LOX 0 0 390 390 1 2
VHL FH 0 0 454 454 1 1
VHL STAT3 0 0 262 262 1 2
VHL EFCAB8 0 0 0 175 1 1
VHL TXN 0 0 254 254 1 1
VHL TGFA 0 0 468 468 1 1
VHL HGF 0 0 217 217 1 2
VHL POU5F1 0 0 233 262 1 2
VHL MCM7 270 0 57 287 1 1
VHL UBB 0 600 0 626 1 1
VHL PECAM1 0 0 245 249 1 1
VHL NF2 43 0 170 171 1 1
VHL ZNF197 270 0 756 817 1 1
VHL HUS1B 0 0 0 288 1 1
VHL ITGA5 270 0 46 287 1 1
VHL CHIT1 183 0 0 183 1 1
VHL GNB2L1 270 0 526 652 1 1
VHL ELL 0 0 181 199 1 1
VHL NR4A1 270 0 516 631 1 2
VHL RALBP1 270 0 0 270 1 1
VHL TUBA1A 294 0 0 365 1 1
VHL LIMD1 486 600 108 800 1 1
VHL HUWE1 270 0 112 333 1 1
VHL CLU 270 0 529 641 1 2
VHL BRD4 800 0 165 836 1 2
VHL CYBA 270 0 75 295 1 1
VHL RHEB 0 0 150 193 1 2
VHL HDAC6 0 0 249 260 1 2
VHL DDIT4 44 0 325 331 1 2
VHL FEM1B 0 0 137 160 1 1
VHL GNPNAT1 0 0 0 151 1 1
VHL HIST1H1B 0 0 0 189 1 1
VHL JAK2 270 0 144 366 1 2
Ontologies
ID Category Term Effect Evidence PubMed
GO:0140297 Molecular Function DNA-binding transcription factor binding enables IPI
GO:0019899 Molecular Function enzyme binding enables IPI
GO:0060090 Molecular Function molecular adaptor activity enables EXP
GO:0005515 Molecular Function protein binding enables IPI
GO:0003711 Molecular Function transcription elongation factor activity enables IDA
GO:1990756 Molecular Function ubiquitin ligase-substrate adaptor activity enables IDA
GO:0004842 Molecular Function ubiquitin-protein transferase activity enables TAS
GO:1990000 Biological Process amyloid fibril formation involved_in EXP
GO:1990000 Biological Process amyloid fibril formation involved_in IDA
GO:0000902 Biological Process cell morphogenesis involved_in NAS
GO:0071456 Biological Process cellular response to hypoxia involved_in TAS
GO:1904262 Biological Process negative regulation of TORC1 signaling involved_in IDA
GO:0043066 Biological Process negative regulation of apoptotic process involved_in NAS
GO:0010507 Biological Process negative regulation of autophagy involved_in IDA
GO:0008285 Biological Process negative regulation of cell population proliferation involved_in IDA
GO:0008285 Biological Process negative regulation of cell population proliferation involved_in IMP
GO:0010629 Biological Process negative regulation of gene expression involved_in IMP
GO:0046426 Biological Process negative regulation of receptor signaling pathway via JAK-STAT involved_in IMP
GO:0009968 Biological Process negative regulation of signal transduction involved_in EXP
GO:0034244 Biological Process negative regulation of transcription elongation by RNA polymerase II involved_in IDA
GO:0061428 Biological Process negative regulation of transcription from RNA polymerase II promoter in response to hypoxia involved_in IDA
GO:0045893 Biological Process positive regulation of DNA-templated transcription involved_in IMP
GO:0045597 Biological Process positive regulation of cell differentiation involved_in NAS
GO:0043161 Biological Process proteasome-mediated ubiquitin-dependent protein catabolic process involved_in IDA
GO:0050821 Biological Process protein stabilization involved_in NAS
GO:0016567 Biological Process protein ubiquitination involved_in IDA
GO:0016567 Biological Process protein ubiquitination involved_in IEA
GO:0016567 Biological Process protein ubiquitination involved_in IMP
GO:0006508 Biological Process proteolysis involved_in TAS
GO:0006355 Biological Process regulation of DNA-templated transcription involved_in IMP
GO:1900037 Biological Process regulation of cellular response to hypoxia involved_in EXP
GO:0010468 Biological Process regulation of gene expression involved_in EXP
GO:0010468 Biological Process regulation of gene expression involved_in IDA
GO:0010468 Biological Process regulation of gene expression involved_in IEP
GO:0005829 Cellular Component cytosol located_in TAS
GO:0005783 Cellular Component endoplasmic reticulum is_active_in IDA
GO:0005783 Cellular Component endoplasmic reticulum located_in NAS
GO:0043232 Cellular Component intracellular non-membrane-bounded organelle is_active_in EXP
GO:0005739 Cellular Component mitochondrion located_in NAS
GO:0005654 Cellular Component nucleoplasm located_in IDA
GO:0005654 Cellular Component nucleoplasm located_in TAS
GO:0005634 Cellular Component nucleus located_in TAS
GO:0005886 Cellular Component plasma membrane located_in IEA
Pathways
Name DB ID
Cellular response to hypoxia Reactome R-HSA-1234174
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha Reactome R-HSA-1234176
Adaptive Immune System Reactome R-HSA-1280218
Signal Transduction Reactome R-HSA-162582
Disease Reactome R-HSA-1643685
Immune System Reactome R-HSA-168256
Cellular responses to stress Reactome R-HSA-2262752
SUMOylation Reactome R-HSA-2990846
SUMO E3 ligases SUMOylate target proteins Reactome R-HSA-3108232
SUMOylation of ubiquitinylation proteins Reactome R-HSA-3232142
Metabolism of proteins Reactome R-HSA-392499
Infectious disease Reactome R-HSA-5663205
Post-translational protein modification Reactome R-HSA-597592
Neddylation Reactome R-HSA-8951664
Cellular responses to stimuli Reactome R-HSA-8953897
SARS-CoV-1 Infection Reactome R-HSA-9678108
SARS-CoV Infections Reactome R-HSA-9679506
SARS-CoV-1 Genome Replication and Transcription Reactome R-HSA-9679514
Replication of the SARS-CoV-1 genome Reactome R-HSA-9682706
SARS-CoV-2 Infection Reactome R-HSA-9694516
SARS-CoV-2 Genome Replication and Transcription Reactome R-HSA-9694682
Replication of the SARS-CoV-2 genome Reactome R-HSA-9694686
RHOBTB3 ATPase cycle Reactome R-HSA-9706019
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Reactome R-HSA-9716542
Early SARS-CoV-2 Infection Events Reactome R-HSA-9772572
Viral Infection Pathways Reactome R-HSA-9824446
Antigen processing: Ubiquitination & Proteasome degradation Reactome R-HSA-983168
Class I MHC mediated antigen processing & presentation Reactome R-HSA-983169
Clear cell renal cell carcinoma pathways (WP4018) WikiPathways WP4018_r123404
Amplification and expansion of oncogenic pathways as metastatic traits (WP3678) WikiPathways WP3678_r117647
Type 2 papillary renal cell carcinoma (WP4241) WikiPathways WP4241_r123413
Transcripts
Accession Version MolecularType Name NCBI Comments
NR_176335 1 miscRNA transcript variant 4 NC_000003 Reference
NM_001354723 2 mRNA transcript variant 3 NC_000003 Reference
NM_000551 4 mRNA transcript variant 1 NC_000003 Reference
NM_198156 3 mRNA transcript variant 2 NC_000003 Reference