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TRPV1

transient receptor potential cation channel subfamily V member 1
General Information
Name transient receptor potential cation channel subfamily V member 1
Alias
  • transient receptor potential cation channel subfamily V member 1
  • OTRPC1
  • capsaicin receptor
  • osm-9-like TRP channel 1
  • transient receptor potential vanilloid 1a
  • transient receptor potential vanilloid 1b
  • vanilloid receptor subtype 1
Gene_family Ankyrin repeat domain containing|Transient receptor potential cation channels
organism Homo sapiens
entrez_id 7442
location 17p13.2
transcript_count 4
exon_count 19
Location
by NCBI GRCh38.p14
Summary
    Entrez Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene. [provided by RefSeq, Jul 2008]
    Stringdb Transient receptor potential cation channel, subfamily V, member 1; Ligand-activated non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli. Seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons. Involved in mediation of inflammatory pain and hyperalgesia. Sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, which involves PKC isozymes and PCL. Activation by vanilloids, like capsaicin, and temperatures higher than 42 degrees Celsius, exhibit [...]
    nextProt Ligand-activated non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli. Seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons. Involved in mediation of inflammatory pain and hyperalgesia. Sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, which involves PKC isozymes and PCL. Activation by vanilloids, like capsaicin, and temperatures higher than 42 degrees Celsius, exhibits a time- and Ca(2+)-dependent outward rectification, followed by a long-lasting refractory state. Mild extracellular acidic pH (6.5) potentiates channel activation by noxious heat and vanilloids, whereas acidic conditions (pH <6) directly activate the channel. Can be activated by endogenous compounds, including 12-hydroperoxytetraenoic acid and bradykinin. Acts as ionotropic endocannabinoid receptor with central neuromodulatory effects. Triggers a form of long-term depression (TRPV1-LTD) mediated by the endocannabinoid anandamine in the hippocampus and nucleus accumbens by affecting AMPA receptors endocytosis.
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
TRPV1 BioGRID TRIM67 GeneID BioGRID Affinity Capture-MS
TRPV1 BioGRID HNRNPH1 GeneID BioGRID Affinity Capture-RNA
TRPV1 BioGRID AKAP5 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
TRPV1 BioGRID EGFR GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
TRPV1 BioGRID CBL GeneID BioGRID Affinity Capture-Western
TRPV1 Protein SYT9 GeneID HPRD
TRPV1 Protein ITCH GeneID HPRD
TRPV1 Protein TRPV2 GeneID HPRD
TRPV1 Protein TRPV1 GeneID HPRD
TRPV1 Protein PRKCE GeneID HPRD
TRPV1 Protein CALM1 GeneID HPRD
TRPV1 BioGRID OS9 GeneID BioGRID Affinity Capture-Western
TRPV1 BioGRID TRPV1 GeneID BioGRID Affinity Capture-Western
TRPV1 BioGRID CALM1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
TRPV1 BioGRID SYT9 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
TRPV1 BioGRID SNAPIN GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
StringDB
A B experiments database textmining combined score hadb nhadb
TRPV1 TRPC4 0 0 709 381 1 1
TRPV1 GRM1 0 0 382 390 1 1
TRPV1 CYBB 0 0 253 252 1 2
TRPV1 GPR65 0 0 547 555 1 1
TRPV1 IL13 0 0 288 288 1 2
TRPV1 SLC1A1 0 0 164 165 1 1
TRPV1 REN 0 0 219 219 1 1
TRPV1 ABHD4 0 0 392 403 1 1
TRPV1 GPER1 0 0 165 166 1 2
TRPV1 ALOX5 0 0 322 321 1 1
TRPV1 GPR6 0 0 205 220 1 1
TRPV1 KCNQ3 0 0 325 334 1 1
TRPV1 ACE 0 0 261 293 1 1
TRPV1 KLK5 0 0 247 246 1 1
TRPV1 CASP3 0 0 403 416 1 2
TRPV1 KCNIP1 0 0 73 164 1 1
TRPV1 PTGS2 0 0 556 586 1 2
TRPV1 AP1G1 0 0 293 293 1 1
TRPV1 P2RY4 0 0 292 292 1 1
TRPV1 SSTR2 0 0 125 174 1 1
TRPV1 CCKAR 0 0 234 273 1 1
TRPV1 PLA2G6 0 0 159 164 1 1
TRPV1 OS9 270 0 0 270 1 1
TRPV1 TRIB3 0 0 140 158 1 2
TRPV1 HCRT 0 0 296 305 1 1
TRPV1 P2RX3 0 0 854 894 1 1
TRPV1 CXCL1 0 0 253 263 1 2
TRPV1 TRPM2 0 0 606 692 1 2
TRPV1 IL33 0 0 208 208 1 2
TRPV1 CSF1 0 0 155 154 1 1
TRPV1 CDH23 0 0 57 173 1 1
TRPV1 AKAP1 0 0 877 877 1 1
TRPV1 KCNJ10 0 0 244 263 1 1
TRPV1 KCNK16 0 0 171 172 1 1
TRPV1 EFCAB9 0 0 81 159 1 1
TRPV1 PROKR2 0 0 268 280 1 1
TRPV1 TRPV5 0 0 716 281 1 1
TRPV1 WNK2 0 0 0 152 1 1
TRPV1 CEBPB 0 0 62 223 1 2
TRPV1 PTGIR 0 0 246 284 1 1
TRPV1 CCDC80 0 0 0 208 1 1
TRPV1 TRPM3 0 0 791 827 1 1
TRPV1 KLF2 0 0 0 199 1 1
TRPV1 CACNA1H 0 0 560 590 1 1
TRPV1 KLK11 0 0 155 154 1 1
TRPV1 NTF3 0 0 406 419 1 1
TRPV1 GRIN3A 0 0 95 185 1 1
TRPV1 S100B 0 0 183 183 1 1
TRPV1 FOLH1 0 0 539 539 1 1
TRPV1 ARRB1 0 0 150 239 1 1
TRPV1 NUDT9 0 0 296 404 1 1
TRPV1 ADM 0 0 234 234 1 2
TRPV1 GK 0 0 0 213 1 1
TRPV1 SST 0 0 718 724 1 1
TRPV1 CALM2 0 0 0 504 1 1
TRPV1 ARRB2 0 0 308 465 1 1
TRPV1 SLC4A5 0 0 150 168 1 1
TRPV1 KCNQ2 0 0 501 562 1 1
TRPV1 SOD2 0 0 152 151 1 2
TRPV1 GNB3 0 0 194 194 1 1
TRPV1 TAS1R3 0 0 424 444 1 1
TRPV1 GPBAR1 0 0 294 294 1 1
TRPV1 TACR2 0 0 370 374 1 1
TRPV1 CACNA1I 0 0 405 407 1 1
TRPV1 KLK9 0 0 193 193 1 1
TRPV1 ADRBK1 0 0 242 242 1 1
TRPV1 CNGA3 0 0 141 200 1 1
TRPV1 TPTE2 0 0 0 207 1 1
TRPV1 GFRA3 0 0 175 400 1 1
TRPV1 FTH1 0 0 134 152 1 1
TRPV1 GPR119 0 0 660 702 1 1
TRPV1 VIPR1 0 0 157 163 1 1
TRPV1 PDYN 0 0 459 459 1 1
TRPV1 RAMP1 0 0 452 466 1 1
TRPV1 AVPR1A 0 0 203 218 1 1
TRPV1 FOXN1 0 0 0 157 1 1
TRPV1 FAF1 0 0 435 508 1 1
TRPV1 AQP4 0 0 205 370 1 1
TRPV1 SCNN1A 0 0 96 296 1 1
TRPV1 ENSG00000250424 0 0 0 183 1 1
TRPV1 KCNK18 0 0 519 559 1 1
TRPV1 KCNK12 0 0 135 150 1 1
TRPV1 IL31 0 0 468 487 1 1
TRPV1 GHSR 0 0 232 245 1 1
TRPV1 SV2A 0 0 273 285 1 1
TRPV1 FOS 0 0 605 666 1 2
TRPV1 KCNK10 0 0 469 519 1 1
TRPV1 SIGMAR1 0 0 244 244 1 1
TRPV1 KCNJ15 0 0 120 243 1 1
TRPV1 CHRM4 0 0 139 170 1 1
TRPV1 SCN8A 0 0 466 484 1 1
TRPV1 CAV3 0 0 283 298 1 1
TRPV1 HRH3 0 0 120 189 1 1
TRPV1 MCHR1 0 0 434 444 1 1
TRPV1 P2RY11 0 0 217 217 1 1
TRPV1 NAAA 0 0 469 527 1 1
TRPV1 TACR1 0 0 763 791 1 1
TRPV1 PDZD11 0 0 0 279 1 1
TRPV1 GABBR1 0 0 263 569 1 1
TRPV1 AMH 0 0 90 201 1 1
TRPV1 ORAI3 0 0 310 322 1 1
TRPV1 GRIN2B 0 0 451 451 1 1
TRPV1 GNAO1 0 0 170 180 1 1
TRPV1 PTGER3 0 0 358 393 1 1
TRPV1 PLXNA4 0 0 0 252 1 1
TRPV1 TLR2 0 0 266 275 1 2
TRPV1 IL2 0 0 230 236 1 1
TRPV1 OLR1 0 0 67 160 1 2
TRPV1 SNAPIN 270 0 261 497 1 1
TRPV1 HAUS3 0 0 0 242 1 1
TRPV1 STOM 0 0 119 154 1 1
TRPV1 BECN1 0 0 139 154 1 2
TRPV1 PTGES 0 0 213 213 1 1
TRPV1 ABCB1 0 0 173 173 1 2
TRPV1 CAMK2B 0 800 61 807 1 1
TRPV1 BBS5 0 0 357 372 1 1
TRPV1 KIF13B 0 0 702 769 1 1
TRPV1 SIRT1 0 0 254 254 1 2
TRPV1 KCNS1 0 0 286 311 1 1
TRPV1 NOX1 0 0 218 218 1 1
TRPV1 PRL 0 0 232 231 1 1
TRPV1 ESR1 0 0 261 265 1 2
TRPV1 HMGB1 0 0 160 159 1 2
TRPV1 CTSK 0 0 139 170 1 2
TRPV1 TRPA1 0 0 974 990 1 1
TRPV1 ITGAM 0 0 234 240 1 1
TRPV1 P2RY2 0 0 688 688 1 1
TRPV1 AVPR2 0 0 138 176 1 1
TRPV1 PRKD1 0 0 255 578 1 1
TRPV1 CRH 0 0 324 340 1 1
TRPV1 GRIN1 0 0 210 342 1 1
TRPV1 SYP 0 0 229 241 1 1
TRPV1 PLCD3 0 0 0 193 1 1
TRPV1 ATP4A 0 0 325 325 1 1
TRPV1 PLCD1 0 0 43 190 1 1
TRPV1 SLC6A3 0 0 186 186 1 1
TRPV1 GRM2 0 0 314 323 1 1
TRPV1 CXCR3 0 0 90 174 1 1
TRPV1 GDE1 0 0 286 298 1 1
TRPV1 ADRB1 0 0 235 248 1 1
TRPV1 CMA1 0 0 170 170 1 1
TRPV1 KCNN4 0 0 383 387 1 1
TRPV1 MGLL 0 0 706 755 1 1
TRPV1 ICK 0 0 363 400 1 1
TRPV1 PACSIN3 0 0 294 338 1 1
TRPV1 CNGA4 0 0 135 227 1 1
TRPV1 NRTN 0 0 391 402 1 1
TRPV1 AQP9 0 0 66 163 1 1
TRPV1 CALCRL 0 0 325 334 1 1
TRPV1 CAMK2A 0 800 95 814 1 2
TRPV1 OR2C1 0 0 61 159 1 1
TRPV1 HINT1 0 0 146 162 1 1
TRPV1 KCNK5 0 0 230 246 1 1
TRPV1 CACNA1E 0 0 262 275 1 1
TRPV1 PRKCA 0 0 218 218 1 1
TRPV1 RAB11FIP3 0 0 0 173 1 1
TRPV1 FAAH2 0 0 391 390 1 1
TRPV1 ELANE 0 0 142 157 1 1
TRPV1 LPAR2 0 0 142 173 1 1
TRPV1 MPST 0 0 161 161 1 1
TRPV1 BBS9 0 0 357 357 1 1
TRPV1 RARS 0 0 148 198 1 1
TRPV1 PTH2 0 0 107 158 1 1
TRPV1 GAL 0 0 491 504 1 1
TRPV1 FN1 0 0 212 212 1 2
TRPV1 KCNA4 0 0 421 457 1 1
TRPV1 CASR 0 0 212 240 1 2
TRPV1 BEST2 0 0 181 186 1 1
TRPV1 SSTR1 0 0 124 162 1 1
TRPV1 GPR132 0 0 325 349 1 1
TRPV1 GAD2 0 0 218 218 1 1
TRPV1 NTF4 0 0 392 397 1 1
TRPV1 KCNA3 0 0 420 450 1 1
TRPV1 CLCN3 0 0 248 256 1 1
TRPV1 KCNA2 0 0 613 652 1 1
TRPV1 DFNB31 0 0 444 458 1 1
TRPV1 SLC4A4 0 0 134 170 1 1
TRPV1 KCNK2 0 0 731 760 1 1
TRPV1 CCL28 0 0 245 244 1 1
TRPV1 GOT2 0 0 151 150 1 1
TRPV1 CCL3 0 0 261 281 1 1
TRPV1 AGRP 0 0 213 213 1 1
TRPV1 KLK6 0 0 156 155 1 1
TRPV1 SOX10 0 0 156 161 1 1
TRPV1 RET 0 0 218 271 1 1
TRPV1 OPRD1 0 0 338 349 1 1
TRPV1 DLG4 0 0 234 250 1 2
TRPV1 SYT2 0 0 118 152 1 1
TRPV1 TJP1 0 0 194 194 1 1
TRPV1 HTR2B 0 0 244 262 1 1
TRPV1 TAC1 0 0 915 928 1 1
TRPV1 CXCL2 0 0 142 154 1 1
TRPV1 IL10 0 0 391 427 1 2
TRPV1 KCNK4 0 0 601 637 1 1
TRPV1 DBH 0 0 209 258 1 1
TRPV1 PIEZO1 0 0 469 505 1 1
TRPV1 GFRA1 0 0 369 386 1 1
TRPV1 PKDREJ 0 0 170 221 1 1
TRPV1 CNRIP1 0 0 181 187 1 1
TRPV1 GFAP 0 0 391 406 1 2
TRPV1 KCNJ12 0 0 209 241 1 1
TRPV1 FTL 0 0 454 454 1 1
TRPV1 MBP 0 0 157 178 1 2
TRPV1 GABARAP 0 0 264 264 1 2
TRPV1 MAPK7 0 0 139 153 1 1
TRPV1 FPR1 0 0 166 180 1 1
TRPV1 GPR68 0 0 455 456 1 1
TRPV1 VEGFA 0 0 325 325 1 2
TRPV1 TRPV3 0 0 956 163 1 1
TRPV1 NFATC1 0 0 146 170 1 2
TRPV1 LTB4R2 0 0 253 266 1 1
TRPV1 DRD3 0 0 124 160 1 1
TRPV1 FFAR4 0 0 269 291 1 1
TRPV1 STOML3 0 0 732 732 1 1
TRPV1 TAS2R16 0 0 132 305 1 1
TRPV1 NTRK3 0 0 459 500 1 1
TRPV1 S1PR1 0 0 141 163 1 1
TRPV1 SYK 0 0 108 158 1 2
TRPV1 SYT5 0 0 66 234 1 1
TRPV1 LEP 0 0 358 396 1 1
TRPV1 NFKBIA 0 0 171 190 1 2
TRPV1 KIT 0 0 219 219 1 2
TRPV1 CCKBR 0 0 123 323 1 1
TRPV1 WT1 0 0 0 200 1 1
TRPV1 PKD2L1 0 0 595 622 1 1
TRPV1 UCP1 0 0 395 406 1 2
TRPV1 ANO2 0 0 166 251 1 1
TRPV1 NPPC 0 0 171 180 1 1
TRPV1 NGFR 0 0 295 305 1 1
TRPV1 NPY1R 0 0 189 203 1 1
TRPV1 ENSG00000258947 0 0 170 235 1 1
TRPV1 MAPK14 0 0 277 353 1 2
TRPV1 ARTN 0 0 566 611 1 1
TRPV1 PTH2R 0 0 123 177 1 1
TRPV1 MGEA5 0 0 150 165 1 1
TRPV1 GALR1 0 0 181 195 1 1
TRPV1 KCND1 0 0 181 192 1 1
TRPV1 PLCE1 0 0 61 205 1 1
TRPV1 VPRBP 0 0 0 188 1 1
TRPV1 ATP2A2 0 0 113 248 1 1
TRPV1 P2RY6 0 0 261 261 1 1
TRPV1 GPR35 0 0 235 235 1 1
TRPV1 HPRT1 0 0 181 181 1 1
TRPV1 HPCA 0 0 0 166 1 1
TRPV1 HTR3B 0 0 193 231 1 1
TRPV1 OPRM1 0 0 723 728 1 1
TRPV1 GRIA1 0 0 314 318 1 1
TRPV1 TXN 0 0 115 175 1 1
TRPV1 ENSG00000264813 0 0 260 282 1 1
TRPV1 DNAJB7 0 0 181 181 1 1
TRPV1 CAT 0 0 296 308 1 2
TRPV1 PECAM1 0 0 181 181 1 1
TRPV1 RAB3IP 0 0 305 305 1 1
TRPV1 PSMA3 0 0 0 186 1 1
TRPV1 AVIL 0 0 390 438 1 1
TRPV1 CNGB3 0 0 73 170 1 1
TRPV1 ADRB2 0 0 341 352 1 1
TRPV1 AGTR1 0 0 155 249 1 1
TRPV1 GRP 0 0 505 529 1 2
TRPV1 DAGLB 0 0 470 476 1 1
TRPV1 AHR 0 0 108 152 1 2
TRPV1 KCNQ4 0 0 244 281 1 1
TRPV1 RIC8B 0 0 183 194 1 1
TRPV1 ASIC1 0 0 607 693 1 2
TRPV1 PROK2 0 0 272 272 1 1
TRPV1 NTRK1 0 0 681 741 1 1
TRPV1 AOC2 0 0 164 163 1 1
TRPV1 EDNRA 0 0 302 314 1 1
TRPV1 P2RY10 0 0 67 151 1 1
TRPV1 KCNA1 0 0 370 437 1 1
TRPV1 SAG 0 0 321 406 1 1
TRPV1 CBL 270 0 0 270 1 1
TRPV1 SCN11A 0 0 681 707 1 1
TRPV1 LOX 0 0 393 439 1 2
TRPV1 NPFF 0 0 144 194 1 1
TRPV1 GCM2 0 0 0 162 1 1
TRPV1 NCF1 0 0 151 169 1 1
TRPV1 AKAP5 270 0 940 984 1 1
TRPV1 ADRA2C 0 0 151 180 1 1
TRPV1 STIM1 0 0 465 501 1 2
TRPV1 AQP3 0 0 182 334 1 1
TRPV1 CACNA1B 0 0 503 514 1 1
TRPV1 SSTR4 0 0 123 176 1 1
TRPV1 NOS3 0 0 543 547 1 2
TRPV1 KCNK9 0 0 500 511 1 1
TRPV1 SEMA3A 0 0 181 181 1 1
TRPV1 TAS2R3 0 0 122 508 1 1
TRPV1 CALCB 0 0 334 352 1 1
TRPV1 IL5 0 0 235 235 1 1
TRPV1 ATP12A 0 0 334 334 1 1
TRPV1 CMKLR1 0 0 324 335 1 1
TRPV1 GCG 0 0 342 342 1 1
TRPV1 FGF2 0 0 160 161 1 2
TRPV1 IL31RA 0 0 413 474 1 1
TRPV1 NPR3 0 0 143 169 1 1
TRPV1 TMEM150C 0 0 139 215 1 1
TRPV1 SLC17A9 0 0 202 202 1 1
TRPV1 KCNJ3 0 0 218 294 1 1
TRPV1 TAS1R2 0 0 390 413 1 1
TRPV1 SLC17A8 0 0 426 439 1 1
TRPV1 PRLR 0 0 143 196 1 1
TRPV1 NAPEPLD 0 0 842 885 1 1
TRPV1 SCN4A 0 0 292 305 1 1
TRPV1 CNR1 0 0 944 968 1 1
TRPV1 BEST1 0 0 195 210 1 1
TRPV1 ATF3 0 0 455 493 1 2
TRPV1 MAPK1 0 0 157 175 1 2
TRPV1 IGF1 0 0 298 303 1 2
TRPV1 SNAP25 0 0 391 404 1 1
TRPV1 OXTR 0 0 252 265 1 1
TRPV1 TNF 0 0 561 659 1 2
TRPV1 PLA2G2A 0 0 163 175 1 1
TRPV1 PLCB1 0 0 160 249 1 1
TRPV1 LINS 0 0 46 206 1 1
TRPV1 KCNH5 0 0 65 154 1 1
TRPV1 ANKRD1 0 0 103 227 1 1
TRPV1 AQP5 0 0 203 307 1 1
TRPV1 BDNF 0 0 605 638 1 2
TRPV1 HTR2C 0 0 184 209 1 1
TRPV1 KCND2 0 0 320 329 1 1
TRPV1 PIK3R2 0 0 101 197 1 1
TRPV1 ABHD6 0 0 527 719 1 1
TRPV1 ADCY6 0 0 57 178 1 1
TRPV1 MMP3 0 0 155 169 1 1
TRPV1 GPR55 0 0 826 896 1 1
TRPV1 GPR4 0 0 343 369 1 1
TRPV1 TAC3 0 0 294 294 1 1
TRPV1 DAGLA 0 0 602 607 1 1
TRPV1 CNGA2 0 0 150 239 1 1
TRPV1 CBSL 0 0 218 236 1 1
TRPV1 GRM4 0 0 218 234 1 1
TRPV1 NMB 0 0 267 296 1 1
TRPV1 RBFOX3 0 0 455 502 1 1
TRPV1 NFAT5 0 0 69 168 1 1
TRPV1 ASIC2 0 0 681 695 1 1
TRPV1 MRGPRX3 0 0 150 236 1 1
TRPV1 IFT140 0 0 0 220 1 1
TRPV1 KCNK13 0 0 143 155 1 1
TRPV1 TRPM1 0 0 681 735 1 1
TRPV1 AKT1 0 0 496 565 1 2
TRPV1 PRDM4 0 0 141 179 1 1
TRPV1 PPARG 0 0 506 518 1 2
TRPV1 CSF2 0 0 181 181 1 1
TRPV1 KCNJ5 0 0 181 181 1 1
TRPV1 GRIK1 0 0 260 261 1 1
TRPV1 CACNA2D1 0 0 187 204 1 1
TRPV1 PRDM16 0 0 253 266 1 1
TRPV1 BBIP1 0 0 295 295 1 1
TRPV1 KLK14 0 0 181 181 1 1
TRPV1 CD4 0 0 285 300 1 2
TRPV1 PRKCG 0 0 457 457 1 1
TRPV1 SCN9A 0 0 720 762 1 1
TRPV1 VCAM1 0 0 207 227 1 1
TRPV1 KCNAB2 0 0 118 299 1 1
TRPV1 VIP 0 0 417 428 1 1
TRPV1 NTRK2 0 0 520 557 1 1
TRPV1 SCN5A 0 0 323 528 1 1
TRPV1 ALOX5AP 0 0 112 160 1 1
TRPV1 PANX1 0 0 393 453 1 1
TRPV1 LNP1 0 0 293 342 1 1
TRPV1 KCNJ6 0 0 260 260 1 1
TRPV1 NOX4 0 0 216 233 1 2
TRPV1 PSMD5 0 0 354 354 1 1
TRPV1 BMP8B 0 0 170 171 1 1
TRPV1 REG4 0 0 0 188 1 1
TRPV1 NFATC4 0 0 134 152 1 1
TRPV1 GRM5 0 0 629 634 1 1
TRPV1 FAAH 0 0 878 909 1 1
TRPV1 TAS1R1 0 0 374 397 1 1
TRPV1 GJA1 0 0 292 292 1 1
TRPV1 CCK 0 0 459 499 1 1
TRPV1 KCNAB1 0 0 112 184 1 1
TRPV1 HRH2 0 0 235 248 1 1
TRPV1 ANKRD65 0 0 0 189 1 1
TRPV1 EDNRB 0 0 290 308 1 1
TRPV1 CXCL10 0 0 171 173 1 2
TRPV1 NR1I2 0 0 218 218 1 1
TRPV1 TPM3 0 0 412 424 1 1
TRPV1 ENTPD3 0 0 124 178 1 1
TRPV1 LTB4R 0 0 284 296 1 1
TRPV1 FUCA1 0 0 0 231 1 1
TRPV1 SCGN 0 0 113 270 1 1
TRPV1 PKD2 0 0 559 619 1 2
TRPV1 ENSG00000274276 0 0 218 236 1 1
TRPV1 NGF 0 0 821 873 1 2
TRPV1 KAL1 0 0 0 355 1 1
TRPV1 KLK1 0 0 162 161 1 1
TRPV1 PNOC 0 0 310 316 1 1
TRPV1 MRGPRD 0 0 710 745 1 1
TRPV1 HRASLS5 0 0 187 204 1 1
TRPV1 KLK4 0 0 171 171 1 1
TRPV1 KCNJ1 0 0 180 198 1 1
TRPV1 OPRK1 0 0 310 322 1 1
TRPV1 TH 0 0 460 481 1 2
TRPV1 MCU 0 0 171 171 1 2
TRPV1 TNFSF11 0 0 249 248 1 2
TRPV1 APOE 0 0 166 165 1 2
TRPV1 OXT 0 0 391 394 1 1
TRPV1 SLC2A4 0 0 158 184 1 1
TRPV1 SRC 0 800 370 878 1 2
TRPV1 ORAI2 0 0 267 279 1 1
TRPV1 CRTC1 0 0 155 154 1 2
TRPV1 CRCP 0 0 193 208 1 1
TRPV1 PKD1 0 0 502 584 1 1
TRPV1 TLR3 0 0 195 201 1 2
TRPV1 HRH1 0 0 666 724 1 1
TRPV1 CAMK2D 0 800 0 802 1 1
TRPV1 LPAR1 0 0 425 440 1 1
TRPV1 BSDC1 0 0 96 188 1 1
TRPV1 EIF2AK3 0 0 372 372 1 2
TRPV1 POU4F1 0 0 341 341 1 1
TRPV1 COMT 0 0 459 464 1 1
TRPV1 HTR2A 0 0 391 416 1 1
TRPV1 GAD1 0 0 233 232 1 1
TRPV1 P2RY13 0 0 167 167 1 1
TRPV1 PRKD3 0 0 0 303 1 1
TRPV1 CACNA1A 0 0 326 397 1 1
TRPV1 TLX3 0 0 194 212 1 1
TRPV1 HMOX1 0 0 243 242 1 2
TRPV1 SLC17A7 0 0 371 385 1 1
TRPV1 PRKD2 0 0 0 303 1 1
TRPV1 HTR1D 0 0 294 312 1 1
TRPV1 P2RX1 0 0 504 531 1 1
TRPV1 KCNN2 0 0 134 152 1 1
TRPV1 LPAR4 0 0 156 155 1 1
TRPV1 CYP2C9 0 0 183 183 1 1
TRPV1 AGTR2 0 0 134 184 1 1
TRPV1 KDR 0 0 134 227 1 2
TRPV1 HCN1 0 0 185 185 1 1
TRPV1 GLUL 0 0 216 216 1 1
TRPV1 ADORA2B 0 0 378 389 1 1
TRPV1 TPRA1 0 0 400 433 1 1
TRPV1 F2R 0 0 150 151 1 1
TRPV1 KCNQ5 0 0 248 274 1 1
TRPV1 CSN3 0 0 391 390 1 1
TRPV1 MC4R 0 0 138 153 1 1
TRPV1 VDAC1 0 0 146 204 1 2
TRPV1 HRH4 0 0 378 431 1 1
TRPV1 GPR12 0 0 212 235 1 1
TRPV1 GRM6 0 0 269 328 1 1
TRPV1 DHCR24 0 0 0 189 1 1
TRPV1 PRKCD 0 0 210 230 1 2
TRPV1 ASIC3 0 0 830 848 1 1
TRPV1 CYP2D6 0 0 142 157 1 1
TRPV1 MMP9 0 0 283 282 1 2
TRPV1 KEAP1 0 0 194 194 1 2
TRPV1 MAPK3 0 0 458 482 1 2
TRPV1 INS 0 0 517 526 1 2
TRPV1 ACTB 0 0 501 536 1 2
TRPV1 KLK12 0 0 181 181 1 1
TRPV1 NEFH 0 0 322 498 1 1
TRPV1 ENSG00000258555 0 0 210 224 1 1
TRPV1 EPRS 0 0 403 413 1 1
TRPV1 FPR2 0 0 194 208 1 1
TRPV1 CAV2 0 0 235 235 1 1
TRPV1 KCNT1 0 0 264 269 1 1
TRPV1 GLP1R 0 0 181 239 1 1
TRPV1 P2RX2 0 0 681 733 1 1
TRPV1 CHRM1 0 0 203 203 1 1
TRPV1 SYT1 0 0 194 204 1 1
TRPV1 CEBPA 0 0 72 290 1 1
TRPV1 PKD1L3 0 0 393 419 1 1
TRPV1 PANX2 0 0 184 263 1 1
TRPV1 CRP 0 0 140 159 1 2
TRPV1 OPN4 0 0 205 257 1 1
TRPV1 HSP90AA1 0 0 158 157 1 2
TRPV1 TAS2R38 0 0 292 292 1 1
TRPV1 TMC2 0 0 74 167 1 1
TRPV1 NEUROG1 0 0 150 169 1 1
TRPV1 ADORA2A 0 0 391 401 1 1
TRPV1 ICAM1 0 0 218 233 1 2
TRPV1 TAS2R1 0 0 0 189 1 1
TRPV1 TRPM5 0 0 688 824 1 1
TRPV1 PTPRC 0 0 125 165 1 1
TRPV1 ESR2 0 0 260 266 1 1
TRPV1 TLR5 0 0 143 162 1 1
TRPV1 CRLF2 0 0 173 191 1 1
TRPV1 SCN7A 0 0 235 262 1 1
TRPV1 FABP5 0 0 157 175 1 1
TRPV1 PLA2G1B 0 0 416 416 1 1
TRPV1 SYN1 0 0 182 181 1 1
TRPV1 PYY 0 0 320 366 1 1
TRPV1 MRGPRX4 0 0 205 215 1 1
TRPV1 MIP 0 0 108 166 1 1
TRPV1 TIMP1 0 0 170 185 1 1
TRPV1 CXCL12 0 0 181 181 1 2
TRPV1 SPR 0 0 107 202 1 1
TRPV1 SLC32A1 0 0 233 232 1 1
TRPV1 SCN1B 0 0 163 163 1 1
TRPV1 TAS2R14 0 0 83 181 1 1
TRPV1 HNRNPH1 270 0 0 270 1 1
TRPV1 GSR 0 0 175 175 1 1
TRPV1 GNRH1 0 0 142 160 1 1
TRPV1 AR 0 0 142 157 1 2
TRPV1 KCNH2 0 0 391 404 1 1
TRPV1 PARP1 0 0 112 173 1 2
TRPV1 RHOA 0 0 233 232 1 2
TRPV1 PRKACB 0 800 0 826 1 1
TRPV1 SSTR3 0 0 330 341 1 1
TRPV1 PRDM12 0 0 183 200 1 1
TRPV1 PLCH2 0 0 45 193 1 1
TRPV1 MMP2 0 0 243 242 1 2
TRPV1 RUNX3 0 0 134 169 1 1
TRPV1 PKD2L2 0 0 510 532 1 1
TRPV1 USP40 0 0 0 188 1 1
TRPV1 KCNK6 0 0 170 169 1 1
TRPV1 CNR2 0 0 557 662 1 1
TRPV1 ALOX15B 0 0 106 182 1 1
TRPV1 NFATC3 0 0 136 154 1 1
TRPV1 TRPC7 0 0 48 273 1 1
TRPV1 GRIN2D 0 0 142 157 1 1
TRPV1 KCNMB1 0 0 181 182 1 1
TRPV1 GAP43 0 0 337 348 1 1
TRPV1 UCHL1 0 0 602 643 1 2
TRPV1 CD8A 0 0 167 167 1 1
TRPV1 MCOLN2 0 0 339 454 1 1
TRPV1 MCOLN3 0 0 509 594 1 1
TRPV1 P2RY1 0 0 470 584 1 1
TRPV1 TRPM6 0 0 616 720 1 1
TRPV1 LTA 0 0 86 183 1 1
TRPV1 P2RY12 0 0 266 266 1 1
TRPV1 GALR2 0 0 194 208 1 1
TRPV1 CCR5 0 0 135 166 1 1
TRPV1 TRPC5 0 0 732 390 1 1
TRPV1 KLK13 0 0 171 171 1 1
TRPV1 P2RX6 0 0 246 246 1 1
TRPV1 CYSLTR1 0 0 61 162 1 1
TRPV1 GRIN2A 0 0 289 288 1 1
TRPV1 ANK1 0 0 805 878 1 1
TRPV1 PENK 0 0 320 342 1 1
TRPV1 P2RX5 0 0 466 473 1 1
TRPV1 TTC8 0 0 537 547 1 1
TRPV1 PLCG1 0 0 407 428 1 1
TRPV1 ADRA1A 0 0 123 153 1 1
TRPV1 ASIC4 0 0 502 554 1 1
TRPV1 CNGA1 0 0 180 236 1 1
TRPV1 SCN3A 0 0 468 504 1 1
TRPV1 NPY2R 0 0 310 332 1 1
TRPV1 ITPR3 0 0 390 418 1 1
TRPV1 JUN 0 0 324 323 1 2
TRPV1 KL 0 0 63 160 1 2
TRPV1 KCNK3 0 0 460 493 1 1
TRPV1 DPYSL2 0 0 151 150 1 1
TRPV1 KCNB2 0 0 113 172 1 1
TRPV1 CALB1 0 0 217 296 1 1
TRPV1 PLCB4 0 0 0 189 1 1
TRPV1 NPPB 0 0 321 367 1 1
TRPV1 KCNN1 0 0 155 155 1 1
TRPV1 TAS2R31 0 0 193 214 1 1
TRPV1 HPCAL1 0 0 45 173 1 1
TRPV1 SLC8A1 0 0 170 179 1 1
TRPV1 AIF1 0 0 391 438 1 2
TRPV1 FAM19A4 0 0 243 277 1 1
TRPV1 CAV1 0 0 294 360 1 2
TRPV1 CASP1 0 0 182 181 1 2
TRPV1 NOS1 0 0 391 415 1 1
TRPV1 KLK8 0 0 167 167 1 1
TRPV1 DNTT 0 0 152 151 1 1
TRPV1 BDKRB1 0 0 210 238 1 1
TRPV1 GPR110 0 0 228 241 1 1
TRPV1 CACNB3 0 0 102 191 1 1
TRPV1 EGF 0 0 296 296 1 2
TRPV1 IL17A 0 0 292 298 1 2
TRPV1 TLR7 0 0 248 266 1 2
TRPV1 CYCS 0 0 248 248 1 2
TRPV1 RGL2 0 0 95 239 1 1
TRPV1 POMC 0 0 390 394 1 1
TRPV1 SLC1A2 0 0 269 269 1 1
TRPV1 ITPR1 0 0 391 419 1 2
TRPV1 CASP9 0 0 229 230 1 2
TRPV1 ACHE 0 0 293 293 1 2
TRPV1 PPARA 0 0 600 609 1 2
TRPV1 CCR2 0 0 343 354 1 2
TRPV1 VAMP1 0 0 204 223 1 1
TRPV1 TACR3 0 0 260 379 1 1
TRPV1 ATP2C2 0 0 155 154 1 1
TRPV1 NES 0 0 182 181 1 2
TRPV1 TRPC6 0 0 710 790 1 1
TRPV1 CHAT 0 0 260 260 1 1
TRPV1 CRHR1 0 0 218 218 1 1
TRPV1 CX3CR1 0 0 246 259 1 1
TRPV1 PIK3R1 0 0 76 253 1 1
TRPV1 MC1R 0 0 151 166 1 1
TRPV1 HSPA4 0 0 167 167 1 1
TRPV1 CRHR2 0 0 159 165 1 1
TRPV1 KCNV1 0 0 101 153 1 1
TRPV1 CCR1 0 0 150 180 1 1
TRPV1 NR3C1 0 0 163 183 1 1
TRPV1 AQP6 0 0 113 183 1 1
TRPV1 PTGER4 0 0 391 438 1 1
TRPV1 VANGL2 0 0 329 329 1 1
TRPV1 FLG 0 0 143 152 1 1
TRPV1 P2RX7 0 0 503 512 1 2
TRPV1 GRM3 0 0 210 220 1 1
TRPV1 STIM2 0 0 260 288 1 1
TRPV1 VR1 800 0 0 800 1 1
TRPV1 GABBR2 0 0 71 267 1 1
TRPV1 BEST3 0 0 171 172 1 1
TRPV1 PSPN 0 0 153 152 1 1
TRPV1 CALCA 0 0 882 925 1 1
TRPV1 CATSPER2 0 0 108 163 1 1
TRPV1 TRPM8 0 0 950 977 1 1
TRPV1 AKAP13 0 0 166 166 1 1
TRPV1 MAPK8 0 0 179 179 1 2
TRPV1 PMS1 0 0 0 188 1 1
TRPV1 ADIPOQ 0 0 233 254 1 2
TRPV1 RYR1 0 0 335 349 1 2
TRPV1 MLN 0 0 253 252 1 2
TRPV1 CTH 0 0 261 287 1 1
TRPV1 KCNC4 0 0 213 264 1 1
TRPV1 HOXD1 0 0 82 173 1 1
TRPV1 SYT9 270 0 823 865 1 1
TRPV1 KCNIP3 0 0 150 247 1 1
TRPV1 ABCA1 0 0 148 201 1 2
TRPV1 IAPP 0 0 148 167 1 2
TRPV1 ABCC8 0 0 206 211 1 1
TRPV1 BDKRB2 0 0 420 545 1 1
TRPV1 CYP3A4 0 0 193 193 1 1
TRPV1 AVP 0 0 170 169 1 1
TRPV1 HTR1A 0 0 559 586 1 1
TRPV1 IL1A 0 0 241 246 1 1
TRPV1 AQP2 0 0 143 229 1 1
TRPV1 ATP2A1 0 0 90 156 1 1
TRPV1 PDE4A 0 0 154 153 1 1
TRPV1 HTR7 0 0 320 343 1 1
TRPV1 NMBR 0 0 161 224 1 1
TRPV1 LGALS4 0 0 174 173 1 1
TRPV1 PLCD4 0 0 0 209 1 1
TRPV1 GFRA2 0 0 89 227 1 1
TRPV1 TMC1 0 0 122 214 1 1
TRPV1 DPP4 0 0 140 178 1 1
TRPV1 DRD2 0 0 262 293 1 1
TRPV1 BCHE 0 0 125 190 1 1
TRPV1 MME 0 0 134 150 1 1
TRPV1 BBS10 0 0 434 434 1 1
TRPV1 PDC 0 0 81 160 1 1
TRPV1 PVALB 0 0 391 448 1 1
TRPV1 CTNS 0 0 642 642 1 2
TRPV1 ADRB3 0 0 269 288 1 1
TRPV1 KNG1 0 0 827 827 1 1
TRPV1 CCL2 0 0 457 461 1 2
TRPV1 MRGPRX2 0 0 123 259 1 1
TRPV1 ALB 0 0 503 579 1 2
TRPV1 CD68 0 0 232 241 1 2
TRPV1 LEPR 0 0 246 245 1 1
TRPV1 BBS7 0 0 610 633 1 1
TRPV1 CNTF 0 0 181 181 1 1
TRPV1 MYLK 0 0 167 167 1 1
TRPV1 TUBB3 0 0 167 219 1 1
TRPV1 PLCL2 0 0 0 199 1 1
TRPV1 VAMP2 0 0 166 167 1 1
TRPV1 HVCN1 0 0 323 340 1 1
TRPV1 SCT 0 0 184 184 1 1
TRPV1 OPRL1 0 0 218 242 1 1
TRPV1 TRPM4 0 0 734 781 1 1
TRPV1 MRGPRX1 0 0 405 427 1 1
TRPV1 DDC 0 0 136 170 1 1
TRPV1 KCNJ13 0 0 122 205 1 1
TRPV1 IL4 0 0 324 333 1 1
TRPV1 TPTE 0 0 57 220 1 1
TRPV1 ADRA2A 0 0 185 223 1 1
TRPV1 SLC12A2 0 0 391 406 1 1
TRPV1 ENPP2 0 0 259 258 1 1
TRPV1 SLC17A6 0 0 508 529 1 1
TRPV1 ADCY5 0 0 448 603 1 1
TRPV1 CDK5 0 0 338 367 1 2
TRPV1 PPARD 0 0 92 188 1 1
TRPV1 CACNA1F 0 0 181 195 1 1
TRPV1 CALM3 0 0 74 522 1 1
TRPV1 TMEM100 0 0 420 456 1 1
TRPV1 BHLHE22 0 0 376 400 1 1
TRPV1 CACNA1D 0 0 245 258 1 1
TRPV1 CHRNA3 0 0 134 188 1 1
TRPV1 KLK7 0 0 170 169 1 1
TRPV1 SCNN1B 0 0 213 232 1 1
TRPV1 GHRL 0 0 325 325 1 1
TRPV1 STAT3 0 0 288 300 1 2
TRPV1 GDNF 0 0 603 620 1 2
TRPV1 WNK1 0 0 94 199 1 1
TRPV1 SCNN1G 0 0 124 375 1 1
TRPV1 HBEGF 0 0 155 154 1 1
TRPV1 TGFA 0 0 322 321 1 1
TRPV1 CSRNP3 0 0 60 156 1 1
TRPV1 PTPN22 0 0 180 222 1 1
TRPV1 INPP5E 0 0 122 492 1 1
TRPV1 MCOLN1 0 0 600 625 1 2
TRPV1 MUC5AC 0 0 162 180 1 1
TRPV1 EDN2 0 0 445 457 1 1
TRPV1 KCND3 0 0 324 333 1 1
TRPV1 EGFR 270 0 244 424 1 2
TRPV1 MYD88 0 0 179 183 1 2
TRPV1 ADORA3 0 0 370 381 1 1
TRPV1 FFAR1 0 0 234 237 1 1
TRPV1 SPATA22 0 0 218 255 1 1
TRPV1 TSLP 0 0 377 377 1 1
TRPV1 GK2 0 0 0 177 1 1
TRPV1 CFTR 0 0 245 244 1 2
TRPV1 PRKCE 0 800 339 883 1 1
TRPV1 SCN10A 0 0 801 852 1 1
TRPV1 TP53 0 0 205 205 1 2
TRPV1 LCN2 0 0 306 306 1 1
TRPV1 SLC12A5 0 0 334 339 1 1
TRPV1 ALOX15 0 0 325 363 1 1
TRPV1 MAOA 0 0 150 156 1 1
TRPV1 ORAI1 0 0 470 479 1 1
TRPV1 PRKACG 0 800 0 828 1 1
TRPV1 DDIT3 0 0 156 186 1 2
TRPV1 NTSR1 0 0 134 217 1 1
TRPV1 P2RX4 0 0 545 568 1 1
TRPV1 SLC2A2 0 0 149 182 1 1
TRPV1 STC1 0 0 113 174 1 1
TRPV1 ANO1 0 0 607 775 1 1
TRPV1 SHANK1 0 0 48 151 1 1
TRPV1 KCNN3 0 0 211 211 1 1
TRPV1 FAM19A1 0 0 141 227 1 1
TRPV1 S1PR2 0 0 161 161 1 1
TRPV1 ACPP 0 0 123 213 1 1
TRPV1 ALOX12 0 0 379 379 1 1
TRPV1 SLC6A1 0 0 137 165 1 1
TRPV1 CACNA1S 0 0 299 331 1 1
TRPV1 AQP1 0 0 194 313 1 1
TRPV1 WNK4 0 0 57 167 1 1
TRPV1 F2RL1 0 0 556 623 1 1
TRPV1 GRPR 0 0 530 611 1 1
TRPV1 CNGB1 0 0 126 218 1 1
TRPV1 NPY 0 0 504 539 1 1
TRPV1 BBS2 0 0 572 572 1 1
TRPV1 SCN3B 0 0 139 225 1 1
TRPV1 PPARGC1A 0 0 260 260 1 2
TRPV1 TPH1 0 0 267 278 1 1
TRPV1 PI3 0 0 170 169 1 2
TRPV1 PLCB3 0 0 347 391 1 1
TRPV1 TNK1 0 0 0 155 1 1
TRPV1 HTR1B 0 0 328 355 1 1
TRPV1 ASNA1 0 0 0 173 1 1
TRPV1 SLC6A4 0 0 324 323 1 1
TRPV1 IL18 0 0 167 173 1 2
TRPV1 IL1R1 0 0 202 202 1 1
TRPV1 PPIG 0 0 271 271 1 1
TRPV1 WDPCP 0 0 244 243 1 1
TRPV1 GPR151 0 0 113 160 1 1
TRPV1 SLC1A3 0 0 211 226 1 1
TRPV1 HTR1F 0 0 290 302 1 1
TRPV1 ANO3 0 0 140 179 1 1
TRPV1 KCNC2 0 0 150 198 1 1
TRPV1 SERPINA6 0 0 282 294 1 1
TRPV1 PLCB2 0 0 240 308 1 1
TRPV1 NTS 0 0 270 285 1 1
TRPV1 SCN2A 0 0 310 335 1 1
TRPV1 YIPF3 0 0 134 188 1 1
TRPV1 GNAQ 0 0 457 469 1 1
TRPV1 ADORA1 0 0 419 429 1 1
TRPV1 GNAT3 0 0 233 262 1 1
TRPV1 STOML1 0 0 95 151 1 1
TRPV1 KLK15 0 0 170 169 1 1
TRPV1 RELA 0 0 95 234 1 2
TRPV1 NPR1 0 0 310 315 1 1
TRPV1 BBS4 0 0 576 576 1 1
TRPV1 TUBB4A 0 0 442 442 1 1
TRPV1 TPCN1 0 0 162 161 1 1
TRPV1 KCNK1 0 0 301 323 1 1
TRPV1 ITPR2 0 0 160 199 1 1
TRPV1 ADCYAP1 0 0 325 340 1 1
TRPV1 KITLG 0 0 143 170 1 1
TRPV1 GJB2 0 0 134 178 1 1
TRPV1 SLC9A1 0 0 194 275 1 1
TRPV1 CACNA1G 0 0 338 353 1 1
TRPV1 CX3CL1 0 0 323 362 1 1
TRPV1 NOS2 0 0 218 223 1 2
TRPV1 MAP2K7 0 0 234 234 1 1
TRPV1 KCNB1 0 0 392 435 1 2
TRPV1 SLC18A3 0 0 297 302 1 1
TRPV1 GPR3 0 0 193 207 1 1
TRPV1 TRPC3 0 0 746 806 1 1
TRPV1 GAPDH 0 0 468 487 1 2
TRPV1 LPAR5 0 0 302 302 1 1
TRPV1 TLR4 0 0 459 496 1 2
TRPV1 ENTPD2 0 0 194 201 1 1
TRPV1 SLC6A5 0 0 284 285 1 1
TRPV1 HTR3A 0 0 456 483 1 1
TRPV1 KCNC1 0 0 265 293 1 1
TRPV1 PIN4 0 0 171 222 1 1
TRPV1 CCL5 0 0 237 254 1 2
TRPV1 CREB1 0 0 409 436 1 2
TRPV1 NOX3 0 0 498 517 1 1
TRPV1 IFNG 0 0 180 211 1 2
TRPV1 RAPGEF3 0 0 280 280 1 1
TRPV1 GAST 0 0 203 217 1 1
TRPV1 PANX3 0 0 210 321 1 1
TRPV1 TPCN2 0 0 181 186 1 1
TRPV1 RYR2 0 0 218 235 1 1
TRPV1 GPR18 0 0 601 665 1 1
TRPV1 GPR32 0 0 320 319 1 1
TRPV1 PIEZO2 0 0 651 728 1 1
TRPV1 SHPK 0 0 261 565 1 1
TRPV1 CALB2 0 0 214 275 1 1
TRPV1 KCNJ11 0 0 210 259 1 1
TRPV1 PRKACA 0 800 0 828 1 1
TRPV1 WNT11 0 0 0 256 1 1
TRPV1 PTGER1 0 0 427 437 1 1
TRPV1 NAV1 0 0 391 390 1 1
TRPV1 NCS1 0 0 181 261 1 1
TRPV1 GRIK2 0 0 150 169 1 1
TRPV1 SCNN1D 0 0 156 250 1 1
TRPV1 TRPC1 0 0 735 870 1 1
TRPV1 KCNG4 0 0 124 154 1 1
TRPV1 PCSK6 0 0 154 154 1 1
TRPV1 PROKR1 0 0 455 464 1 1
TRPV1 OR2W1 0 0 60 152 1 1
TRPV1 RAPGEF4 0 0 291 290 1 1
TRPV1 WNT8A 0 0 0 158 1 1
TRPV1 ANXA5 0 0 142 157 1 2
TRPV1 FGF21 0 0 107 162 1 2
TRPV1 OPN5 0 0 150 181 1 1
TRPV1 GRIA2 0 0 243 242 1 1
TRPV1 OSMR 0 0 202 219 1 1
TRPV1 KCNE1 0 0 147 165 1 1
TRPV1 RYR3 0 0 155 173 1 1
TRPV1 POTEF 0 0 100 164 1 1
TRPV1 CALM1 270 0 70 756 1 1
TRPV1 PSMC6 0 0 154 153 1 1
TRPV1 BBS12 0 0 437 437 1 1
TRPV1 MTOR 0 0 268 284 1 2
TRPV1 KCNH1 0 0 211 286 1 1
TRPV1 TRPV6 0 0 814 289 1 1
TRPV1 MMP1 0 0 215 215 1 1
TRPV1 HCN2 0 0 235 240 1 1
TRPV1 PTGS1 0 0 335 340 1 1
TRPV1 RRAS 0 0 0 190 1 1
TRPV1 CXCR4 0 0 186 201 1 2
TRPV1 TNFRSF1A 0 0 241 240 1 1
TRPV1 OCLN 0 0 205 205 1 1
TRPV1 KCNMA1 0 0 367 435 1 1
TRPV1 PLEK 0 0 167 185 1 1
TRPV1 CATSPER1 0 0 268 268 1 1
TRPV1 KCNA5 0 0 213 284 1 1
TRPV1 GRM8 0 0 181 358 1 1
TRPV1 ELAVL3 0 0 150 229 1 1
TRPV1 PIRT 0 0 873 890 1 1
TRPV1 LPAR3 0 0 204 231 1 1
TRPV1 GRM7 0 0 167 265 1 1
TRPV1 NALCN 0 0 165 165 1 1
TRPV1 ABHD12 0 0 413 504 1 1
TRPV1 IL6 0 0 562 607 1 2
TRPV1 UCP2 0 0 284 284 1 2
TRPV1 MPZ 0 0 175 201 1 1
TRPV1 ACAN 0 0 135 153 1 1
TRPV1 MPO 0 0 346 363 1 2
TRPV1 PRKG1 0 0 270 270 1 1
TRPV1 KLK3 0 0 291 290 1 1
TRPV1 KCNJ8 0 0 240 239 1 1
TRPV1 KCNQ1 0 0 249 266 1 1
TRPV1 CXCL8 0 0 458 457 1 2
TRPV1 WNK3 0 0 0 152 1 1
TRPV1 IL1B 0 0 596 606 1 2
TRPV1 TRPM7 0 0 709 788 1 1
TRPV1 BBS1 0 0 602 610 1 1
TRPV1 ISL1 0 0 181 181 1 1
TRPV1 P2RY14 0 0 181 181 1 1
TRPV1 EDN1 0 0 460 482 1 1
TRPV1 HIF1A 0 0 213 213 1 2
TRPV1 YPEL5 0 0 52 151 1 1
TRPV1 KCNIP2 0 0 81 189 1 1
TRPV1 GCK 0 0 150 168 1 1
TRPV1 PKD1L1 0 0 180 208 1 1
TRPV1 VIPR2 0 0 193 193 1 1
TRPV1 CACNA1C 0 0 405 456 1 1
TRPV1 HCN4 0 0 150 167 1 1
TRPV1 RHO 0 0 348 370 1 2
TRPV1 PLA2G4A 0 0 181 187 1 1
TRPV1 CXCR2 0 0 213 226 1 1
TRPV1 APP 0 0 181 181 1 2
TRPV1 EGR1 0 0 125 157 1 2
TRPV1 S1PR3 0 0 260 260 1 1
TRPV1 LIPE 0 0 166 165 1 1
TRPV1 ASRGL1 0 0 0 181 1 1
TRPV1 SCN1A 0 0 458 467 1 1
TRPV1 CTNNB1 0 0 181 206 1 2
TRPV1 ASPA 0 0 210 280 1 1
VR1 FGF21 0 0 107 162 2 1
VR1 ANXA5 0 0 142 157 2 1
VR1 IFNG 0 0 180 211 2 1
VR1 CREB1 0 0 409 436 2 1
VR1 CCL5 0 0 238 255 2 1
VR1 KCNB1 0 0 392 435 2 1
VR1 NOS2 0 0 218 223 2 1
VR1 TLR4 0 0 459 496 2 1
VR1 GAPDH 0 0 468 487 2 1
VR1 RELA 0 0 95 234 2 1
VR1 RHO 0 0 348 370 2 1
VR1 CTNNB1 0 0 181 206 2 1
VR1 TRPV1 800 0 0 800 2 1
VR1 EGR1 0 0 125 157 2 1
VR1 APP 0 0 181 181 2 1
VR1 CXCL8 0 0 458 457 2 1
VR1 HIF1A 0 0 213 213 2 1
VR1 PRKCB 0 0 454 463 2 1
VR1 IL1B 0 0 596 606 2 1
VR1 STAT1 0 0 362 362 2 1
VR1 MPO 0 0 347 364 2 1
VR1 UCP2 0 0 284 284 2 1
VR1 IL6 0 0 562 607 2 1
VR1 MTOR 0 0 268 284 2 1
VR1 CXCR4 0 0 187 202 2 1
VR1 DDIT3 0 0 156 186 2 1
VR1 MYD88 0 0 179 183 2 1
VR1 EGFR 0 0 244 243 2 1
VR1 TP53 0 0 204 204 2 1
VR1 CFTR 0 0 245 244 2 1
VR1 STAT3 0 0 288 300 2 1
VR1 GDNF 0 0 603 620 2 1
VR1 MCOLN1 0 0 684 704 2 1
VR1 PI3 0 0 438 438 2 1
VR1 PPARGC1A 0 0 260 260 2 1
VR1 IL18 0 0 167 173 2 1
VR1 ADIPOQ 0 0 233 254 2 1
VR1 MAPK8 0 0 179 179 2 1
VR1 P2RX7 0 0 503 512 2 1
VR1 NES 0 0 182 181 2 1
VR1 CCR2 0 0 344 355 2 1
VR1 PPARA 0 0 600 609 2 1
VR1 ACHE 0 0 293 293 2 1
VR1 IL17A 0 0 292 298 2 1
VR1 EGF 0 0 297 297 2 1
VR1 ITPR1 0 0 531 554 2 1
VR1 CASP9 0 0 229 230 2 1
VR1 CYCS 0 0 248 248 2 1
VR1 TLR7 0 0 248 266 2 1
VR1 CDK5 0 0 338 367 2 1
VR1 CTNS 0 0 642 642 2 1
VR1 CD68 0 0 232 241 2 1
VR1 ALB 0 0 503 579 2 1
VR1 CCL2 0 0 457 461 2 1
VR1 IAPP 0 0 148 167 2 1
VR1 ABCA1 0 0 148 201 2 1
VR1 MLN 0 0 253 252 2 1
VR1 RYR1 0 0 478 489 2 1
VR1 CXCL12 0 0 181 181 2 1
VR1 AR 0 0 138 153 2 1
VR1 RHOA 0 0 233 232 2 1
VR1 PARP1 0 0 112 173 2 1
VR1 ICAM1 0 0 218 233 2 1
VR1 CRP 0 0 140 159 2 1
VR1 HSP90AA1 0 0 158 157 2 1
VR1 MAPK3 0 0 458 482 2 1
VR1 MMP9 0 0 283 282 2 1
VR1 KEAP1 0 0 194 194 2 1
VR1 ACTB 0 0 501 536 2 1
VR1 INS 0 0 468 477 2 1
VR1 CAV1 0 0 474 524 2 1
VR1 AIF1 0 0 391 438 2 1
VR1 CASP1 0 0 182 181 2 1
VR1 JUN 0 0 324 323 2 1
VR1 KL 0 0 63 160 2 1
VR1 MMP2 0 0 243 242 2 1
VR1 UCHL1 0 0 602 643 2 1
VR1 PKD2 0 0 559 619 2 1
VR1 TH 0 0 460 481 2 1
VR1 NGF 0 0 814 868 2 1
VR1 CXCL10 0 0 171 173 2 1
VR1 NOX4 0 0 216 233 2 1
VR1 PPARG 0 0 509 522 2 1
VR1 AKT1 0 0 828 851 2 1
VR1 CD4 0 0 285 300 2 1
VR1 VDAC1 0 0 147 205 2 1
VR1 PRKCD 0 0 204 224 2 1
VR1 HMOX1 0 0 243 242 2 1
VR1 KDR 0 0 134 227 2 1
VR1 TLR3 0 0 195 201 2 1
VR1 EIF2AK3 0 0 325 325 2 1
VR1 APOE 0 0 166 165 2 1
VR1 TNFSF11 0 0 249 248 2 1
VR1 MCU 0 0 171 171 2 1
VR1 CRTC1 0 0 155 154 2 1
VR1 SRC 0 0 623 652 2 1
VR1 STIM1 0 0 465 501 2 1
VR1 NOS3 0 0 469 473 2 1
VR1 AHR 0 0 108 152 2 1
VR1 GRP 0 0 505 529 2 1
VR1 LOX 0 0 393 439 2 1
VR1 ASIC1 0 0 607 693 2 1
VR1 CAT 0 0 296 308 2 1
VR1 TNF 0 0 561 659 2 1
VR1 BDNF 0 0 605 638 2 1
VR1 ATF3 0 0 455 493 2 1
VR1 IGF1 0 0 298 303 2 1
VR1 MAPK1 0 0 157 175 2 1
VR1 FGF2 0 0 160 161 2 1
VR1 FN1 0 0 212 212 2 1
VR1 CASR 0 0 212 240 2 1
VR1 SIRT1 0 0 254 254 2 1
VR1 CTSK 0 0 139 170 2 1
VR1 HMGB1 0 0 160 159 2 1
VR1 ESR1 0 0 260 264 2 1
VR1 KIT 0 0 219 219 2 1
VR1 NFKBIA 0 0 171 190 2 1
VR1 SYK 0 0 108 158 2 1
VR1 MAPK14 0 0 277 353 2 1
VR1 UCP1 0 0 395 406 2 1
VR1 VEGFA 0 0 325 325 2 1
VR1 MBP 0 0 157 178 2 1
VR1 NFATC1 0 0 146 170 2 1
VR1 DLG4 0 0 466 478 2 1
VR1 GFAP 0 0 391 406 2 1
VR1 IL10 0 0 391 427 2 1
VR1 VTI1B 0 0 450 450 2 1
VR1 ADM 0 0 234 234 2 1
VR1 CEBPB 0 0 62 223 2 1
VR1 PTGS2 0 0 556 586 2 1
VR1 CASP3 0 0 403 416 2 1
VR1 IL33 0 0 208 208 2 1
VR1 TRPM2 0 0 606 692 2 1
VR1 CXCL1 0 0 253 263 2 1
VR1 TRIB3 0 0 140 158 2 1
VR1 CYBB 0 0 253 252 2 1
VR1 GPER1 0 0 165 166 2 1
VR1 IL13 0 0 288 288 2 1
VR1 TLR2 0 0 267 276 2 1
VR1 ABCB1 0 0 173 173 2 1
VR1 BECN1 0 0 139 154 2 1
VR1 OLR1 0 0 67 160 2 1
VR1 FOS 0 0 605 666 2 1
VR1 SOD2 0 0 152 151 2 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0005524 Molecular Function ATP binding enables ISS
GO:0005262 Molecular Function calcium channel activity enables IBA
GO:0005262 Molecular Function calcium channel activity enables TAS
GO:0015278 Molecular Function calcium-release channel activity enables ISS
GO:0005516 Molecular Function calmodulin binding enables ISS
GO:0017081 Molecular Function chloride channel regulator activity enables IEA
GO:0005231 Molecular Function excitatory extracellular ligand-gated monoatomic ion channel activity enables ISS
GO:0005230 Molecular Function extracellular ligand-gated monoatomic ion channel activity enables IDA
GO:0042802 Molecular Function identical protein binding enables IEA
GO:0046872 Molecular Function metal ion binding enables IEA
GO:0035091 Molecular Function phosphatidylinositol binding enables ISS
GO:0051219 Molecular Function phosphoprotein binding enables IPI
GO:0005515 Molecular Function protein binding enables IPI
GO:0097603 Molecular Function temperature-gated ion channel activity enables IEA
GO:0004888 Molecular Function transmembrane signaling receptor activity enables ISS
GO:0005245 Molecular Function voltage-gated calcium channel activity enables TAS
GO:0048266 Biological Process behavioral response to pain involved_in IEA
GO:0098703 Biological Process calcium ion import across plasma membrane involved_in IBA
GO:0098703 Biological Process calcium ion import across plasma membrane involved_in IDA
GO:0070588 Biological Process calcium ion transmembrane transport involved_in ISS
GO:0070588 Biological Process calcium ion transmembrane transport involved_in TAS
GO:0007166 Biological Process cell surface receptor signaling pathway involved_in TAS
GO:0071318 Biological Process cellular response to ATP involved_in ISS
GO:0071468 Biological Process cellular response to acidic pH involved_in IDA
GO:0071312 Biological Process cellular response to alkaloid involved_in ISS
GO:0034605 Biological Process cellular response to heat involved_in IDA
GO:1990090 Biological Process cellular response to nerve growth factor stimulus involved_in IEA
GO:0071502 Biological Process cellular response to temperature stimulus involved_in IEA
GO:0071356 Biological Process cellular response to tumor necrosis factor involved_in IEA
GO:0007635 Biological Process chemosensory behavior involved_in TAS
GO:0050968 Biological Process detection of chemical stimulus involved in sensory perception of pain involved_in IEA
GO:0050965 Biological Process detection of temperature stimulus involved in sensory perception of pain involved_in IEA
GO:0050960 Biological Process detection of temperature stimulus involved in thermoception involved_in IEA
GO:0002024 Biological Process diet induced thermogenesis involved_in IEA
GO:0060079 Biological Process excitatory postsynaptic potential involved_in IEA
GO:0001660 Biological Process fever generation involved_in IEA
GO:0014047 Biological Process glutamate secretion involved_in IEA
GO:0006629 Biological Process lipid metabolic process involved_in IEA
GO:0001774 Biological Process microglial cell activation involved_in IEA
GO:0090212 Biological Process negative regulation of establishment of blood-brain barrier involved_in IEA
GO:0010459 Biological Process negative regulation of heart rate involved_in IEA
GO:0010917 Biological Process negative regulation of mitochondrial membrane potential involved_in IEA
GO:0003085 Biological Process negative regulation of systemic arterial blood pressure involved_in IEA
GO:0000122 Biological Process negative regulation of transcription by RNA polymerase II involved_in IEA
GO:0002790 Biological Process peptide secretion involved_in IEA
GO:0043065 Biological Process positive regulation of apoptotic process involved_in IEA
GO:0007204 Biological Process positive regulation of cytosolic calcium ion concentration involved_in IEA
GO:0045429 Biological Process positive regulation of nitric oxide biosynthetic process involved_in IEA
GO:0051289 Biological Process protein homotetramerization involved_in ISS
GO:0051209 Biological Process release of sequestered calcium ion into cytosol involved_in IEA
GO:1901594 Biological Process response to capsazepine involved_in IMP
GO:1901594 Biological Process response to capsazepine involved_in ISS
GO:0043434 Biological Process response to peptide hormone involved_in IEA
GO:0050954 Biological Process sensory perception of mechanical stimulus involved_in IEA
GO:0060083 Biological Process smooth muscle contraction involved in micturition involved_in IEA
GO:0050955 Biological Process thermoception acts_upstream_of_or_within IDA
GO:0032591 Cellular Component dendritic spine membrane located_in IEA
GO:0009897 Cellular Component external side of plasma membrane located_in IEA
GO:0016020 Cellular Component membrane located_in IDA
GO:0043025 Cellular Component neuronal cell body located_in IEA
GO:0005886 Cellular Component plasma membrane is_active_in IBA
GO:0005886 Cellular Component plasma membrane located_in ISS
GO:0005886 Cellular Component plasma membrane located_in TAS
GO:0045211 Cellular Component postsynaptic membrane located_in ISS
Pathways
Name DB ID
Stimuli-sensing channels Reactome R-HSA-2672351
TRP channels Reactome R-HSA-3295583
Transport of small molecules Reactome R-HSA-382551
Ion channel transport Reactome R-HSA-983712
Chronic hyperglycemia impairment of neuron function (WP5283) WikiPathways WP5283_r124551
Eicosanoid metabolism via lipooxygenases (LOX) (WP4721) WikiPathways WP4721_r124745
Serotonin and anxiety (WP3947) WikiPathways WP3947_r106483
Transcripts
Accession Version MolecularType Name NCBI Comments
NM_080704 4 mRNA transcript variant 1 NC_000017 Reference
NM_018727 5 mRNA transcript variant 2 NC_000017 Reference
NM_080705 4 mRNA transcript variant 4 NC_000017 Reference
NM_080706 3 mRNA transcript variant 3 NC_000017 Reference