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XBP1

X-box binding protein 1
General Information
Name X-box binding protein 1
Alias
  • X-box-binding protein 1
  • tax-responsive element-binding protein 5
Gene_family Basic leucine zipper proteins
organism Homo sapiens
entrez_id 7494
location 22q12.1
transcript_count 4
exon_count 7
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez This gene encodes a transcription factor that regulates MHC class II genes by binding to a promoter element referred to as an X box. This gene product is a bZIP protein, which was also identified as a cellular transcription factor that binds to an enhancer in the promoter of the T cell leukemia virus type 1 promoter. It may increase expression of viral proteins by acting as the DNA binding partner of a viral transactivator. It has been found that upon accumulation of unfolded proteins in the endoplasmic reticulum (ER), the mRNA of this gene is processed to an active form by an unconventional splicing mechanism that is mediated by the endonuclease inositol-requiring enzyme 1 (IRE1). The resulting loss of 26 nt from the spliced mRNA causes a frame-shift and an isoform XBP1(S), which is the functionally active transcription factor. The isoform encoded by the unspliced mRNA, XBP1(U), is constitutively expressed, and thought to function as a negative feedback regulator of XBP1(S), which shuts off transcription of target genes during the recovery phase of ER stress. A pseudogene of XBP1 has been identified and localized to chromosome 5. [provided by RefSeq, Jul 2008]
    Stringdb X-box-binding protein 1; Functions as a transcription factor during endoplasmic reticulum (ER) stress by regulating the unfolded protein response (UPR). Required for cardiac myogenesis and hepatogenesis during embryonic development, and the development of secretory tissues such as exocrine pancreas and salivary gland (By similarity). Involved in terminal differentiation of B lymphocytes to plasma cells and production of immunoglobulins. Modulates the cellular response to ER stress in a PIK3R-dependent manner. Binds to the cis-acting X box present in the promoter regions of major histoc [...]
    nextProt Functions as a transcription factor during endoplasmic reticulum (ER) stress by regulating the unfolded protein response (UPR). Required for cardiac myogenesis and hepatogenesis during embryonic development, and the development of secretory tissues such as exocrine pancreas and salivary gland (By similarity). Involved in terminal differentiation of B lymphocytes to plasma cells and production of immunoglobulins (PubMed:11460154). Modulates the cellular response to ER stress in a PIK3R-dependent manner (PubMed:20348923). Binds to the cis-acting X box present in the promoter regions of major histocompatibility complex class II genes (PubMed:8349596). Involved in VEGF-induced endothelial cell (EC) proliferation and retinal blood vessel formation during embryonic development but also for angiogenesis in adult tissues under ischemic conditions. Functions also as a major regulator of the UPR in obesity-induced insulin resistance and type 2 diabetes for the management of obesity and diabetes prevention (By similarity).
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
XBP1 BioGRID PRNP GeneID BioGRID Affinity Capture-MS
XBP1 BioGRID GBF1 GeneID BioGRID Positive Genetic
XBP1 BioGRID PIK3R1 GeneID BioGRID Affinity Capture-Western
XBP1 BioGRID FAS GeneID BioGRID Proximity Label-MS
XBP1 BioGRID POU5F1 GeneID BioGRID Affinity Capture-Western
XBP1 BioGRID CEBPD GeneID BioGRID Affinity Capture-Western
XBP1 BioGRID CROCCP2 GeneID BioGRID Affinity Capture-MS
XBP1 BioGRID RIGI GeneID BioGRID Affinity Capture-RNA
XBP1 BioGRID NFYC GeneID BioGRID Affinity Capture-Western
XBP1 BioGRID NFYB GeneID BioGRID Affinity Capture-Western
XBP1 BioGRID NFYA GeneID BioGRID Affinity Capture-Western
XBP1 BioGRID UBE2V1 GeneID BioGRID Two-hybrid
XBP1 BioGRID APEX1 GeneID BioGRID Affinity Capture-RNA
XBP1 BioGRID FBXW7 GeneID BioGRID Affinity Capture-Western
XBP1 BioGRID MDM2 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
XBP1 BioGRID MTNR1B GeneID BioGRID Two-hybrid
XBP1 BioGRID CCDC102B GeneID BioGRID Affinity Capture-MS
XBP1 BioGRID CROCC GeneID BioGRID Affinity Capture-MS
XBP1 BioGRID MCM2 GeneID BioGRID Affinity Capture-MS
XBP1 BioGRID KAT2B GeneID BioGRID Affinity Capture-Western
XBP1 BioGRID KAT2A GeneID BioGRID Affinity Capture-Western
XBP1 BioGRID DERL1 GeneID BioGRID Affinity Capture-Western
XBP1 BioGRID UBE2I GeneID BioGRID Affinity Capture-Western; Two-hybrid
XBP1 BioGRID HM13 GeneID BioGRID Affinity Capture-Western
XBP1 BioGRID XBP1 GeneID BioGRID FRET
XBP1 BioGRID CREBZF GeneID BioGRID FRET
XBP1 BioGRID ATF6 GeneID BioGRID FRET
XBP1 BioGRID ATF6B GeneID BioGRID FRET
XBP1 BioGRID PSMA8 GeneID BioGRID Affinity Capture-Western
XBP1 BioGRID PSMA6 GeneID BioGRID Affinity Capture-Western
XBP1 BioGRID PSMA5 GeneID BioGRID Affinity Capture-Western
XBP1 BioGRID ZNF440 GeneID BioGRID Two-hybrid
XBP1 BioGRID PCBD2 GeneID BioGRID Two-hybrid
XBP1 BioGRID ZNF580 GeneID BioGRID Two-hybrid
XBP1 BioGRID TRIP4 GeneID BioGRID Two-hybrid
XBP1 BioGRID H1-10 GeneID BioGRID Two-hybrid
XBP1 BioGRID FUBP3 GeneID BioGRID Two-hybrid
XBP1 BioGRID NR0B2 GeneID BioGRID Two-hybrid
XBP1 BioGRID SSX4 GeneID BioGRID Two-hybrid
XBP1 BioGRID SRSF1 GeneID BioGRID Two-hybrid
XBP1 BioGRID RBL2 GeneID BioGRID Two-hybrid
XBP1 BioGRID HDGF GeneID BioGRID Two-hybrid
XBP1 BioGRID H1-0 GeneID BioGRID Two-hybrid
XBP1 BioGRID GLI1 GeneID BioGRID Two-hybrid
XBP1 BioGRID IRE1 GeneID BioGRID Protein-RNA
XBP1 Protein XBP1 GeneID HPRD
XBP1 Protein FOS GeneID HPRD
XBP1 Protein ESR1 GeneID HPRD
XBP1 BioGRID FOS GeneID BioGRID Reconstituted Complex
XBP1 BioGRID ESR1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
XBP1 Nucleotide FOXA1 GeneID BIND FOXA1 interacts with XBP-1 enhancer.
XBP1 Nucleotide POLR2A GeneID BIND PolII interacts with XBP-1 enhancer.
XBP1 Nucleotide ESR1 GeneID BIND ER interacts with XBP-1 enhancer.
StringDB
A B experiments database textmining combined score hadb nhadb
XBP1 JUN 0 0 632 661 1 2
XBP1 GTF2H3 270 0 0 270 1 1
XBP1 ITPR3 0 0 455 459 1 1
XBP1 TFF3 0 0 321 337 1 1
XBP1 TAPBP 0 0 180 179 1 1
XBP1 BATF 0 0 166 335 1 1
XBP1 MAN2A1 0 0 47 399 1 1
XBP1 TYK2 0 0 133 155 1 1
XBP1 DAPK1 0 0 167 203 1 2
XBP1 RPL37A 800 0 0 807 1 1
XBP1 GOLGB1 0 0 125 153 1 1
XBP1 CTDSP2 0 900 0 900 1 1
XBP1 MAFB 0 0 141 159 1 1
XBP1 ERGIC3 0 0 171 203 1 1
XBP1 BCL2L11 0 0 562 576 1 2
XBP1 FBXO4 0 0 81 243 1 1
XBP1 LONP2 0 0 82 161 1 1
XBP1 IL10RA 0 0 155 154 1 1
XBP1 SIGLEC1 0 0 81 172 1 1
XBP1 NR2F2 0 0 407 417 1 1
XBP1 AMFR 0 0 332 387 1 1
XBP1 MTHFD2 0 0 128 195 1 1
XBP1 CYP19A1 0 0 165 165 1 2
XBP1 ENSG00000173366 0 0 321 321 1 1
XBP1 SERPINA1 0 0 329 342 1 2
XBP1 MAPK12 0 0 95 165 1 1
XBP1 TPP1 0 900 0 900 1 1
XBP1 TNFSF10 0 0 159 158 1 2
XBP1 CAV1 0 0 156 155 1 2
XBP1 RPL36A 800 0 0 800 1 1
XBP1 AIF1 0 0 156 167 1 2
XBP1 ORMDL3 0 0 460 471 1 2
XBP1 HSPA1A 0 0 536 580 1 1
XBP1 CERS5 0 0 135 269 1 1
XBP1 FFAR2 0 0 156 155 1 1
XBP1 ULK2 0 0 170 171 1 2
XBP1 SH2D3C 0 0 173 173 1 1
XBP1 SLC33A1 0 0 193 263 1 1
XBP1 MAP2K3 0 0 127 218 1 1
XBP1 SELK 0 0 112 152 1 1
XBP1 GTF2H4 270 0 0 270 1 1
XBP1 DNTT 0 0 335 343 1 1
XBP1 NPC2 0 0 53 217 1 1
XBP1 CD27 0 0 340 340 1 1
XBP1 BAG5 0 0 123 151 1 1
XBP1 CYP7A1 0 0 155 154 1 1
XBP1 RERE 0 0 181 181 1 1
XBP1 CXCL6 0 0 46 150 1 1
XBP1 SNCA 0 0 358 362 1 2
XBP1 CASP1 0 0 321 374 1 2
XBP1 CCNA2 0 0 193 193 1 1
XBP1 UBXN4 0 0 167 179 1 1
XBP1 INA 0 0 270 270 1 1
XBP1 GORASP2 0 0 134 195 1 1
XBP1 EIF2AK1 0 0 458 633 1 1
XBP1 ARID5B 0 0 107 153 1 1
XBP1 PCNX 0 0 0 163 1 1
XBP1 KRT8 0 0 166 186 1 1
XBP1 TCF7 0 0 112 349 1 1
XBP1 ID4 0 0 74 166 1 1
XBP1 RIPK2 0 0 143 165 1 2
XBP1 TFAM 0 0 394 394 1 2
XBP1 TRIM3 0 0 459 459 1 1
XBP1 ZBTB17 0 900 0 901 1 1
XBP1 SEL1L2 0 0 0 150 1 1
XBP1 CREB3 0 0 508 529 1 1
XBP1 NCOA3 0 0 180 197 1 1
XBP1 KLHDC3 0 900 0 900 1 1
XBP1 CNPY3 0 0 113 204 1 1
XBP1 ATP5B 0 0 134 166 1 1
XBP1 TNFRSF13C 0 0 220 220 1 1
XBP1 MFN1 0 0 207 207 1 2
XBP1 PSMB8 0 0 194 194 1 1
XBP1 EIF2AK2 0 0 455 742 1 2
XBP1 XRN1 0 0 143 201 1 1
XBP1 IRS2 0 0 268 273 1 1
XBP1 MNAT1 270 0 0 270 1 1
XBP1 CD8A 0 0 391 390 1 1
XBP1 FKBP14 0 900 62 903 1 1
XBP1 ERLEC1 0 0 388 403 1 1
XBP1 BIK 0 0 341 341 1 2
XBP1 DEFA6 0 0 210 210 1 1
XBP1 CALR 0 0 652 797 1 1
XBP1 BMI1 0 0 134 152 1 1
XBP1 RPL3 800 0 0 800 1 1
XBP1 ARNT 0 0 187 220 1 2
XBP1 DNAJC3 0 900 720 986 1 1
XBP1 CDC25C 0 0 96 167 1 2
XBP1 TBL1X 0 0 167 167 1 1
XBP1 PNRC1 0 0 0 150 1 1
XBP1 LTA 0 0 67 210 1 1
XBP1 SOD1 0 0 458 491 1 2
XBP1 CD69 0 0 211 211 1 1
XBP1 ERN2 0 0 740 775 1 1
XBP1 SOX17 0 0 89 165 1 1
XBP1 GOLGA2 0 0 203 203 1 1
XBP1 VCP 0 0 391 406 1 2
XBP1 COPZ1 0 0 90 166 1 1
XBP1 LCK 0 0 161 182 1 1
XBP1 CAPN2 0 0 181 186 1 2
XBP1 RPL4 800 0 0 800 1 1
XBP1 SPOP 0 0 50 180 1 1
XBP1 RPL39 800 0 49 801 1 1
XBP1 CREB3L2 0 0 465 519 1 1
XBP1 LAMP2 0 0 266 303 1 2
XBP1 CCRL2 0 0 181 198 1 1
XBP1 GABARAPL1 0 0 290 316 1 2
XBP1 ICAM1 0 0 243 242 1 2
XBP1 SEC31A 0 900 134 911 1 1
XBP1 CCNB2 0 0 108 244 1 1
XBP1 CD24 0 0 233 232 1 2
XBP1 ENSG00000269590 0 0 0 302 1 1
XBP1 SIRT7 0 0 232 233 1 2
XBP1 CCT4 0 0 95 191 1 1
XBP1 SOX9 0 0 171 171 1 1
XBP1 MS4A1 0 0 202 202 1 1
XBP1 ESR2 0 0 206 220 1 1
XBP1 TRPT1 0 0 193 248 1 1
XBP1 ABCA13 0 0 309 309 1 1
XBP1 PTPRC 0 0 374 374 1 1
XBP1 RPL8 800 0 0 800 1 1
XBP1 MLKL 0 0 125 226 1 2
XBP1 UBE2G2 0 0 160 159 1 1
XBP1 RAB1A 0 0 112 165 1 1
XBP1 CXCL12 0 0 242 241 1 2
XBP1 MTTP 0 0 325 393 1 1
XBP1 SLC38A2 0 0 134 188 1 1
XBP1 TIMP1 0 0 162 161 1 1
XBP1 RPL24 800 0 0 800 1 1
XBP1 BAX 0 0 396 396 1 2
XBP1 GPR29 0 0 174 191 1 1
XBP1 TARDBP 0 0 193 205 1 2
XBP1 CD3D 0 0 213 213 1 1
XBP1 TLR5 0 0 193 193 1 1
XBP1 AR 0 0 286 298 1 2
XBP1 PARP1 0 0 212 266 1 2
XBP1 EIF4G1 0 0 155 181 1 2
XBP1 CRTC2 0 0 251 250 1 1
XBP1 BID 0 0 164 163 1 2
XBP1 INSR 0 0 125 231 1 1
XBP1 HSPA8 0 0 364 424 1 2
XBP1 GSR 0 0 140 192 1 1
XBP1 EXTL1 0 900 0 900 1 1
XBP1 ETV4 0 0 74 235 1 1
XBP1 TNFRSF14 0 0 81 181 1 1
XBP1 ATG9A 0 0 170 207 1 2
XBP1 SPP1 0 0 168 167 1 2
XBP1 ERP44 0 0 385 448 1 1
XBP1 EBAG9 0 0 140 158 1 1
XBP1 CDKN1A 0 0 234 234 1 2
XBP1 NKRF 0 0 183 196 1 1
XBP1 CSF2RA 0 0 203 203 1 1
XBP1 FCGR2B 0 0 161 161 1 1
XBP1 SQSTM1 0 0 420 435 1 2
XBP1 BNIP3 0 0 274 294 1 2
XBP1 TFAP2D 0 0 0 208 1 1
XBP1 RNF5 0 0 208 213 1 1
XBP1 HSFX2 0 0 0 150 1 1
XBP1 ZBTB8OS 0 0 337 352 1 1
XBP1 DDIAS 0 0 63 162 1 1
XBP1 TRAM1 0 0 95 272 1 1
XBP1 PCK2 0 0 181 210 1 1
XBP1 JUNB 0 0 120 190 1 1
XBP1 GLI3 0 0 134 175 1 1
XBP1 SIRT3 0 0 233 234 1 2
XBP1 ABCG1 0 0 134 258 1 2
XBP1 TSPYL2 0 900 45 900 1 1
XBP1 MAPK3 0 0 325 377 1 2
XBP1 B2M 0 0 269 288 1 1
XBP1 MMP9 0 0 217 217 1 2
XBP1 PAX5 0 0 638 652 1 1
XBP1 KEAP1 0 0 304 304 1 2
XBP1 HSPE1 0 0 150 172 1 1
XBP1 TNNT1 0 0 46 211 1 1
XBP1 GLP1R 0 0 181 186 1 1
XBP1 STUB1 0 0 231 230 1 2
XBP1 EDEM2 0 0 539 596 1 1
XBP1 CD40 0 0 376 376 1 2
XBP1 RPS2 800 0 45 802 1 1
XBP1 SPG7 0 0 73 163 1 1
XBP1 ACTB 0 0 635 671 1 2
XBP1 INS 0 0 608 616 1 2
XBP1 ATG13 0 0 267 326 1 2
XBP1 RPL22 800 0 56 803 1 1
XBP1 CRP 0 0 171 171 1 2
XBP1 COX4I1 0 0 181 207 1 1
XBP1 SGPL1 0 0 123 177 1 1
XBP1 ATF2 0 0 141 197 1 1
XBP1 ELF2 0 0 171 298 1 1
XBP1 PSEN1 0 0 203 266 1 2
XBP1 HTRA2 0 0 130 172 1 1
XBP1 CEBPA 0 0 482 502 1 1
XBP1 PRSS1 0 0 211 211 1 1
XBP1 NEUROD1 0 0 151 150 1 1
XBP1 SOX2 0 0 153 152 1 2
XBP1 FBXW7 270 0 85 303 1 2
XBP1 TSPAN13 0 0 44 175 1 1
XBP1 IL21 0 0 135 189 1 1
XBP1 HPGDS 0 0 160 159 1 1
XBP1 SP7 0 0 155 169 1 1
XBP1 UFD1L 0 0 285 301 1 1
XBP1 HSP90AA1 0 0 510 581 1 2
XBP1 PNPLA2 0 0 211 265 1 2
XBP1 CREB3L1 0 0 425 435 1 1
XBP1 PDIA2 0 0 288 568 1 1
XBP1 CTBP1 0 0 56 159 1 1
XBP1 TFEB 0 0 263 293 1 2
XBP1 FOSL1 0 0 115 166 1 1
XBP1 PGK1 0 0 148 168 1 2
XBP1 SGTA 0 0 134 166 1 1
XBP1 KAT2A 270 0 92 309 1 1
XBP1 PSMG2 0 0 146 166 1 1
XBP1 ITLN1 0 0 155 162 1 1
XBP1 HERPUD1 0 0 664 737 1 1
XBP1 ELAVL1 0 0 203 203 1 2
XBP1 MME 0 0 171 171 1 1
XBP1 CUL1 0 0 95 195 1 1
XBP1 CASP7 0 0 392 410 1 1
XBP1 RPL19 800 0 213 846 1 1
XBP1 SNAI2 0 0 145 235 1 1
XBP1 BAG2 0 0 122 162 1 1
XBP1 CREB3L3 0 0 594 617 1 1
XBP1 EIF4A1 0 0 113 154 1 1
XBP1 TMEM14A 0 0 53 212 1 1
XBP1 IGLL5 0 0 297 297 1 1
XBP1 DNAJC12 0 0 122 182 1 1
XBP1 LEPR 0 0 230 229 1 1
XBP1 CD68 0 0 205 223 1 2
XBP1 CASP8 0 0 459 475 1 2
XBP1 ALB 0 0 455 514 1 2
XBP1 CCL2 0 0 371 371 1 2
XBP1 ANXA8 0 0 213 213 1 1
XBP1 BIRC3 0 0 140 212 1 1
XBP1 ADRA2B 0 0 0 161 1 1
XBP1 SEC63 0 0 379 419 1 1
XBP1 SMAD3 0 0 181 181 1 2
XBP1 ONECUT1 0 0 134 208 1 1
XBP1 SPARC 0 0 117 159 1 2
XBP1 SEC23B 0 0 235 378 1 2
XBP1 ERO1L 0 0 651 773 1 1
XBP1 GGH 0 0 164 163 1 1
XBP1 TNFRSF10A 0 0 213 242 1 1
XBP1 MYLK 0 0 84 167 1 1
XBP1 SPOPL 0 0 0 150 1 1
XBP1 ADIPOR1 0 0 113 156 1 1
XBP1 CDK5 0 0 165 175 1 2
XBP1 ANKRD46 0 0 57 158 1 1
XBP1 EP300 0 0 240 293 1 2
XBP1 PDGFRB 0 0 161 161 1 2
XBP1 TECR 0 0 0 165 1 1
XBP1 RGS13 0 0 150 181 1 1
XBP1 LEF1 0 0 150 235 1 1
XBP1 ADRA2A 0 0 0 161 1 1
XBP1 HCFC1 0 0 89 742 1 1
XBP1 CALU 0 0 163 211 1 1
XBP1 IL4 0 0 372 372 1 1
XBP1 MSRB2 0 0 0 190 1 1
XBP1 RPL6 800 0 0 800 1 1
XBP1 RERG 0 0 157 156 1 1
XBP1 MLXIPL 0 0 358 358 1 1
XBP1 SPPL2A 0 0 0 156 1 1
XBP1 RYR1 0 0 134 195 1 2
XBP1 CDH1 0 0 251 250 1 2
XBP1 CERS2 0 0 96 158 1 1
XBP1 YWHAG 0 0 154 212 1 1
XBP1 HYOU1 0 900 566 960 1 1
XBP1 TARS 0 0 90 155 1 1
XBP1 CDK6 0 0 149 164 1 2
XBP1 SMG5 0 0 113 153 1 1
XBP1 DDX58 0 0 287 286 1 1
XBP1 SIRT6 0 0 193 194 1 2
XBP1 ATP2A1 0 0 193 323 1 1
XBP1 CRYGC 0 0 180 179 1 1
XBP1 MAVS 0 0 150 173 1 2
XBP1 IL1A 0 0 181 181 1 1
XBP1 CEACAM1 0 0 82 179 1 1
XBP1 PIK3AP1 0 0 0 221 1 1
XBP1 IAPP 0 0 213 226 1 2
XBP1 RPS12 800 0 0 800 1 1
XBP1 DCTN1 0 900 58 901 1 1
XBP1 ABCA1 0 0 180 186 1 2
XBP1 SLC3A2 0 0 140 160 1 1
XBP1 MYOC 0 0 119 159 1 1
XBP1 MAP3K11 0 0 124 155 1 1
XBP1 GATA1 0 0 212 225 1 1
XBP1 NFIL3 0 0 193 281 1 1
XBP1 LGALS4 0 0 361 372 1 1
XBP1 MAF 0 0 261 262 1 1
XBP1 FAM109A 0 0 430 430 1 1
XBP1 CTGF 0 0 183 183 1 1
XBP1 PPP2R5B 0 900 0 900 1 1
XBP1 PTGER4 0 0 160 177 1 1
XBP1 MBTPS2 0 0 626 709 1 1
XBP1 CISH 0 0 144 192 1 1
XBP1 NR3C1 0 0 207 225 1 1
XBP1 SCFD1 0 0 70 172 1 1
XBP1 DAPK3 0 0 53 184 1 2
XBP1 PRNP 0 0 234 241 1 2
XBP1 BATF3 0 0 146 196 1 1
XBP1 OSTC 0 0 54 153 1 1
XBP1 TFF1 0 0 408 425 1 1
XBP1 RPS27 800 0 0 800 1 1
XBP1 IFIH1 0 0 194 194 1 1
XBP1 SESN2 0 0 294 299 1 2
XBP1 DDRGK1 0 0 293 402 1 1
XBP1 EMC3 0 0 82 150 1 1
XBP1 RPS5 800 0 0 800 1 1
XBP1 CDK5RAP3 0 0 170 169 1 1
XBP1 HSPA6 0 0 159 239 1 1
XBP1 HIST2H3PS2 0 0 260 276 1 1
XBP1 DIABLO 0 0 195 195 1 2
XBP1 FOXP1 0 0 241 256 1 1
XBP1 MUT 0 0 108 173 1 1
XBP1 CD79B 0 0 261 266 1 1
XBP1 GYLTL1B 0 0 229 245 1 1
XBP1 PHLDA1 0 0 165 165 1 1
XBP1 CCDC117 0 0 364 364 1 1
XBP1 MAP2K4 0 0 167 183 1 1
XBP1 EIF2S2 0 0 181 216 1 1
XBP1 IGHV4-38-2 0 0 402 402 1 1
XBP1 SRP19 800 0 0 800 1 1
XBP1 ADIPOQ 0 0 318 317 1 2
XBP1 GRB7 0 0 218 218 1 1
XBP1 MAPK8 0 0 520 599 1 2
XBP1 ARG1 0 0 182 181 1 2
XBP1 GCLC 0 0 194 196 1 1
XBP1 SEC61G 800 0 143 842 1 1
XBP1 VIM 161 0 112 237 1 2
XBP1 SENP1 0 0 161 161 1 1
XBP1 IL17A 0 0 282 282 1 2
XBP1 HNF1A 0 0 233 236 1 1
XBP1 SP4 0 0 261 273 1 1
XBP1 EGF 0 0 290 290 1 2
XBP1 HGSNAT 0 0 186 223 1 1
XBP1 BMP2 0 0 163 181 1 1
XBP1 ETS1 0 0 257 256 1 1
XBP1 FASN 0 0 390 398 1 2
XBP1 PCSK1 0 0 166 167 1 1
XBP1 ARFRP1 0 0 113 174 1 1
XBP1 ITPR1 0 0 455 459 1 2
XBP1 CASP9 0 0 501 516 1 2
XBP1 POMC 0 0 195 196 1 1
XBP1 TRAF6 0 0 252 273 1 2
XBP1 GADD45B 0 0 181 181 1 1
XBP1 CYCS 0 0 510 510 1 2
XBP1 MAN2B2 0 0 0 368 1 1
XBP1 DUSP12 0 0 125 157 1 1
XBP1 PPM1L 0 0 306 306 1 1
XBP1 MAPK9 0 0 323 434 1 2
XBP1 TLR7 0 0 266 266 1 2
XBP1 HSP90B1 0 0 769 887 1 1
XBP1 CEBPD 0 0 216 229 1 1
XBP1 ATP2C2 0 0 0 195 1 1
XBP1 CYP2E1 0 0 254 259 1 2
XBP1 HSPB3 0 0 320 319 1 1
XBP1 RPTOR 0 0 234 245 1 2
XBP1 DLG5 0 0 181 199 1 1
XBP1 CCR2 0 0 155 172 1 2
XBP1 BPTF 0 0 0 159 1 1
XBP1 RPAP2 0 0 155 341 1 1
XBP1 PPARA 0 0 419 434 1 2
XBP1 PPY 0 0 59 189 1 1
XBP1 TRIB1 0 0 61 174 1 1
XBP1 NFYA 270 900 175 934 1 1
XBP1 LPL 0 0 182 181 1 1
XBP1 TATDN2 0 900 0 900 1 1
XBP1 HSPA4 0 0 520 560 1 1
XBP1 PIK3R1 0 0 486 486 1 1
XBP1 DICER1 0 0 204 209 1 1
XBP1 PPIB 0 0 194 242 1 1
XBP1 IGSF3 0 0 57 160 1 1
XBP1 TFAP2E 0 0 0 208 1 1
XBP1 SEC23A 0 0 119 237 1 2
XBP1 TYR 0 0 204 204 1 2
XBP1 RPL17 800 0 0 800 1 1
XBP1 EXTL3 0 900 0 900 1 1
XBP1 RPL17-C18orf32 800 0 0 800 1 1
XBP1 TSPEAR 0 0 412 412 1 1
XBP1 SDHC 0 0 337 361 1 1
XBP1 SLAMF7 0 0 294 294 1 1
XBP1 IGF1R 0 0 204 300 1 2
XBP1 USF1 0 0 150 185 1 1
XBP1 ZNF274 0 0 166 180 1 1
XBP1 BLOC1S1 0 0 413 502 1 1
XBP1 PCK1 0 0 162 163 1 1
XBP1 PPARGC1A 0 0 403 410 1 2
XBP1 MYC 0 0 503 515 1 2
XBP1 IRGM 0 0 468 468 1 2
XBP1 IL15 0 0 160 159 1 1
XBP1 PDK1 0 0 163 163 1 2
XBP1 TLN1 0 900 0 900 1 1
XBP1 WFS1 0 900 502 957 1 1
XBP1 SLC39A6 0 0 299 307 1 1
XBP1 PPIG 0 0 134 152 1 1
XBP1 DGAT1 0 0 263 264 1 2
XBP1 IL18 0 0 261 261 1 2
XBP1 NR0B2 80 0 213 350 1 1
XBP1 MAN1A1 0 0 98 184 1 1
XBP1 PARK2 0 0 266 285 1 1
XBP1 IFNA1 0 0 283 282 1 1
XBP1 RPS26 800 0 46 801 1 1
XBP1 RPL35A 800 0 0 800 1 1
XBP1 PIK3CA 0 0 160 166 1 2
XBP1 PPAP2B 0 0 90 212 1 1
XBP1 ACACA 0 0 294 294 1 1
XBP1 TFAP2B 0 0 0 208 1 1
XBP1 IL2RA 0 0 156 155 1 1
XBP1 RPL15 800 0 53 802 1 1
XBP1 MX1 0 0 184 183 1 1
XBP1 GPX7 0 0 99 161 1 1
XBP1 P4HB 0 0 681 771 1 2
XBP1 TMBIM6 0 0 545 604 1 1
XBP1 SLC7A1 0 0 153 152 1 1
XBP1 RPL27 800 0 48 809 1 1
XBP1 TRAF2 0 0 503 586 1 2
XBP1 RICTOR 0 0 204 204 1 2
XBP1 G6PC 0 0 284 284 1 1
XBP1 UBL5 0 0 74 283 1 1
XBP1 EXTL2 0 900 0 900 1 1
XBP1 PIK3R3 0 0 306 306 1 1
XBP1 NPC1 0 0 95 233 1 2
XBP1 TNFRSF13B 0 0 260 260 1 1
XBP1 NUPR1 0 0 280 297 1 2
XBP1 RPS25 800 0 0 800 1 1
XBP1 ACSL1 0 0 155 154 1 1
XBP1 PARK7 0 0 184 195 1 2
XBP1 EBF2 0 0 53 151 1 1
XBP1 TFR2 0 0 0 224 1 1
XBP1 TCL1B 0 0 143 235 1 1
XBP1 NELFCD 0 0 67 162 1 1
XBP1 GOLPH3 0 0 324 349 1 1
XBP1 C9orf72 0 0 203 224 1 2
XBP1 SMAD4 0 0 136 156 1 2
XBP1 MYCN 0 0 154 198 1 1
XBP1 HDAC3 0 0 181 181 1 2
XBP1 PRSS57 0 0 146 169 1 1
XBP1 GPR78 0 0 460 471 1 1
XBP1 KDELR1 0 0 260 295 1 1
XBP1 CHGA 0 0 66 164 1 1
XBP1 SSR1 0 900 170 918 1 1
XBP1 RPS17 800 0 67 805 1 1
XBP1 KRT4 0 0 162 161 1 1
XBP1 SSR4 0 0 247 422 1 1
XBP1 CHAC1 0 0 459 507 1 1
XBP1 C12orf10 0 0 251 250 1 1
XBP1 CD80 0 0 260 260 1 2
XBP1 PSMA6 270 0 0 270 1 1
XBP1 SEC24C 0 0 96 171 1 1
XBP1 BRCA1 0 0 246 245 1 2
XBP1 FKBP7 0 0 170 189 1 1
XBP1 PPIF 0 0 184 183 1 1
XBP1 MAP2K1 0 0 181 181 1 1
XBP1 SLC29A1 0 0 60 154 1 1
XBP1 TCF3 0 0 210 218 1 1
XBP1 IKZF3 0 0 234 246 1 1
XBP1 RB1CC1 0 0 273 304 1 2
XBP1 TLR1 0 0 150 208 1 1
XBP1 NFE2L2 0 0 563 591 1 2
XBP1 BACH2 0 0 528 559 1 1
XBP1 NKX6-1 0 0 150 171 1 1
XBP1 RPS19 800 0 49 801 1 1
XBP1 FKBP11 0 0 406 456 1 1
XBP1 ENSG00000272772 0 0 0 235 1 1
XBP1 DAB2IP 0 0 195 200 1 2
XBP1 SND1 0 0 123 164 1 1
XBP1 AKT2 0 0 134 186 1 2
XBP1 SLC2A1 0 0 245 244 1 2
XBP1 RPS28 800 0 0 807 1 1
XBP1 TSLP 0 0 167 167 1 1
XBP1 ASB7 0 0 70 198 1 1
XBP1 FBXO6 0 0 150 185 1 1
XBP1 LAMP1 0 0 210 232 1 2
XBP1 FADD 0 0 253 252 1 2
XBP1 LACTB 0 0 391 390 1 1
XBP1 FGFR3 0 0 162 161 1 1
XBP1 HTT 0 0 324 438 1 2
XBP1 MYD88 0 0 325 385 1 2
XBP1 PPP1CC 0 0 218 271 1 1
XBP1 ATP2C1 0 0 117 259 1 1
XBP1 CDK4 0 0 193 193 1 2
XBP1 CFLAR 0 0 269 291 1 2
XBP1 EGFR 0 0 324 338 1 2
XBP1 PTPRCAP 0 0 0 277 1 1
XBP1 TP53 0 0 518 526 1 2
XBP1 LCN2 0 0 140 158 1 1
XBP1 MDM2 270 0 213 400 1 2
XBP1 HMGCS1 0 0 137 161 1 1
XBP1 YIF1A 0 900 0 900 1 1
XBP1 CFTR 0 0 297 297 1 2
XBP1 NR1H2 0 0 74 383 1 1
XBP1 INSIG1 0 0 310 309 1 1
XBP1 CREBZF 458 0 441 684 1 1
XBP1 SLC7A5 0 0 165 181 1 1
XBP1 DDIT3 0 800 870 976 1 2
XBP1 HDAC2 0 0 166 165 1 1
XBP1 MAP3K7 0 0 134 156 1 2
XBP1 TNNT3 0 0 0 207 1 1
XBP1 NFKBIZ 0 0 67 152 1 1
XBP1 PSMA8 270 0 0 270 1 1
XBP1 DNAJA1 0 0 108 199 1 1
XBP1 MAP1A 0 0 203 204 1 2
XBP1 PLP1 0 0 144 164 1 1
XBP1 SCUBE2 0 0 232 231 1 1
XBP1 LMNA 0 900 184 914 1 2
XBP1 SLC2A2 0 0 218 218 1 1
XBP1 RPL36 800 0 0 800 1 1
XBP1 MUC5B 0 0 161 213 1 1
XBP1 NCOR2 0 0 134 167 1 1
XBP1 RPS16 800 0 0 800 1 1
XBP1 IRAK1 0 0 148 189 1 1
XBP1 TRAF1 0 0 108 174 1 1
XBP1 RPL28 800 0 47 801 1 1
XBP1 CARD9 0 0 170 169 1 1
XBP1 FGF7 0 0 52 151 1 1
XBP1 SRSF1 117 0 90 162 1 1
XBP1 MIA3 0 0 168 167 1 1
XBP1 BRD4 0 0 166 166 1 2
XBP1 CTBP2 0 0 95 194 1 1
XBP1 CLU 0 0 151 150 1 2
XBP1 SFTPC 0 0 234 234 1 1
XBP1 ALDH1L2 0 0 154 161 1 1
XBP1 PPARD 0 0 112 160 1 1
XBP1 SH3BP5 0 0 140 159 1 1
XBP1 NR4A1 0 0 170 169 1 2
XBP1 AGR2 0 0 506 524 1 1
XBP1 BRD7 0 0 484 516 1 1
XBP1 JAK2 0 0 242 261 1 2
XBP1 APAF1 0 0 282 392 1 2
XBP1 MTA3 0 0 181 216 1 1
XBP1 HDAC6 0 0 257 256 1 2
XBP1 REG3G 0 0 170 169 1 1
XBP1 SKIV2L 0 0 172 358 1 1
XBP1 PTPN22 0 0 251 252 1 1
XBP1 EIF2AK4 0 0 566 711 1 2
XBP1 ATP6V0D1 0 900 0 906 1 1
XBP1 DEFA5 0 0 207 207 1 1
XBP1 VDAC2 0 0 398 399 1 1
XBP1 EZH2 0 0 218 218 1 2
XBP1 STAT3 0 0 468 479 1 2
XBP1 AATF 0 0 150 177 1 1
XBP1 RPN1 0 0 203 288 1 1
XBP1 ERN1 0 800 986 997 1 2
XBP1 TRIM23 0 0 0 152 1 1
XBP1 GCLM 0 0 204 204 1 1
XBP1 MUC5AC 0 0 170 221 1 1
XBP1 SERPINH1 0 0 310 318 1 1
XBP1 GATA3 0 0 452 468 1 1
XBP1 KRT5 0 0 182 181 1 1
XBP1 FAM46C 0 0 216 233 1 1
XBP1 ELAVL2 0 0 167 167 1 1
XBP1 MSRB3 0 0 70 324 1 1
XBP1 CXCL8 0 0 391 390 1 2
XBP1 MAPK13 0 0 88 159 1 1
XBP1 TARSL2 0 0 155 178 1 1
XBP1 SUMO2 0 0 171 202 1 1
XBP1 DDOST 0 0 138 360 1 1
XBP1 IGLL1 0 0 147 240 1 1
XBP1 IL6R 0 0 193 193 1 1
XBP1 RPL30 800 0 0 800 1 1
XBP1 ATXN1 0 0 82 245 1 1
XBP1 SIRT5 0 0 181 207 1 1
XBP1 GCK 0 0 161 168 1 1
XBP1 NEDD4 0 0 81 172 1 2
XBP1 HIF1A 270 0 988 992 1 2
XBP1 EDN1 0 0 193 193 1 1
XBP1 MLF2 0 0 102 181 1 1
XBP1 BAG3 0 0 137 155 1 2
XBP1 RPS7 800 0 0 800 1 1
XBP1 RPL12 800 0 0 800 1 1
XBP1 IL1B 0 0 503 512 1 2
XBP1 EDEM3 0 0 400 491 1 1
XBP1 NR1H3 0 0 134 423 1 1
XBP1 SP1 0 0 170 205 1 2
XBP1 C3AR1 0 0 322 321 1 1
XBP1 MYOM2 0 0 167 167 1 1
XBP1 PSAT1 0 0 142 175 1 1
XBP1 RHO 0 0 254 274 1 2
XBP1 HCN4 0 0 0 165 1 1
XBP1 SLC38A1 0 0 134 167 1 1
XBP1 PACS2 0 0 180 196 1 1
XBP1 CDK2 0 0 181 201 1 2
XBP1 MAP1LC3A 0 0 231 325 1 2
XBP1 HRAS 0 0 265 265 1 2
XBP1 CTNNB1 0 0 341 356 1 2
XBP1 LIPE 0 0 169 169 1 1
XBP1 GANAB 0 0 170 238 1 1
XBP1 FCRL4 0 0 156 155 1 1
XBP1 EGR1 0 0 286 299 1 2
XBP1 MFN2 0 0 432 432 1 2
XBP1 APP 0 0 269 281 1 2
XBP1 RPL13A 800 0 112 814 1 1
XBP1 MAN1B1 0 0 286 290 1 1
XBP1 MTOR 0 0 469 480 1 2
XBP1 TAOK3 0 0 150 222 1 1
XBP1 NLRP1 0 0 194 194 1 1
XBP1 E2F2 0 0 181 232 1 1
XBP1 POTEF 0 0 268 342 1 1
XBP1 SEC24D 0 0 265 353 1 1
XBP1 CXCR4 0 0 280 295 1 2
XBP1 CYR61 0 0 129 163 1 1
XBP1 FGF13 0 0 154 153 1 1
XBP1 PSEN2 0 0 108 178 1 1
XBP1 CRELD2 0 0 392 486 1 1
XBP1 CD40LG 0 0 373 386 1 1
XBP1 SEC61A1 800 0 518 911 1 1
XBP1 HCN2 0 0 0 165 1 1
XBP1 NOTCH1 0 0 282 283 1 2
XBP1 RPL14 800 0 0 800 1 1
XBP1 POU4F2 0 0 0 179 1 1
XBP1 ELAVL3 0 0 155 154 1 1
XBP1 BCL2L2-PABPN1 0 0 181 181 1 1
XBP1 BRD2 0 0 133 156 1 1
XBP1 STAT1 0 0 298 331 1 2
XBP1 ENDOG 0 0 170 169 1 1
XBP1 OCLN 0 0 160 159 1 1
XBP1 SYVN1 0 900 494 962 1 1
XBP1 NPHS1 0 0 147 166 1 1
XBP1 RPL32 800 0 90 812 1 1
XBP1 MYOG 0 0 143 166 1 1
XBP1 PADI1 0 0 180 199 1 1
XBP1 TNFRSF1A 0 0 267 283 1 1
XBP1 GZMB 0 0 201 201 1 1
XBP1 RPS6 800 0 150 822 1 2
XBP1 PLIN1 0 0 203 203 1 1
XBP1 PIK3C3 0 0 285 326 1 2
XBP1 ETS2 0 0 129 153 1 1
XBP1 CXXC1 0 900 0 901 1 1
XBP1 MPO 0 0 150 178 1 2
XBP1 UCP2 0 0 150 168 1 2
XBP1 HSFX1 0 0 0 150 1 1
XBP1 MPZ 0 0 202 202 1 1
XBP1 NFYB 270 900 155 934 1 1
XBP1 IL6 0 0 559 563 1 2
XBP1 RPL9 800 0 0 800 1 1
XBP1 CTRL 0 0 325 325 1 2
XBP1 SERP1 0 900 420 944 1 1
XBP1 IFNG 0 0 241 298 1 2
XBP1 BIRC2 0 0 181 249 1 1
XBP1 CREB1 0 0 468 485 1 2
XBP1 CCL5 0 0 209 209 1 2
XBP1 TNFRSF17 0 0 341 341 1 1
XBP1 NFE2 0 0 183 239 1 1
XBP1 IGJ 0 0 456 459 1 1
XBP1 SDHB 0 0 167 167 1 1
XBP1 ESRRA 0 0 136 169 1 1
XBP1 CDNF 0 0 207 475 1 1
XBP1 LONP1 0 0 123 231 1 1
XBP1 POMP 0 0 161 161 1 1
XBP1 CREBBP 0 0 203 368 1 1
XBP1 ARF1 0 0 115 153 1 1
XBP1 HSPA1L 0 0 66 154 1 1
XBP1 RYR2 0 0 135 196 1 1
XBP1 IL4R 0 0 154 174 1 1
XBP1 SIRT2 0 0 217 218 1 2
XBP1 SCAP 0 0 234 317 1 1
XBP1 CUL7 0 900 0 900 1 1
XBP1 EPO 0 0 118 154 1 2
XBP1 DPAGT1 0 0 218 235 1 1
XBP1 ATF5 0 0 468 681 1 1
XBP1 HSF1 0 0 211 388 1 2
XBP1 RYR3 0 0 124 186 1 1
XBP1 LMAN1 0 0 240 285 1 1
XBP1 FGF21 0 0 325 326 1 2
XBP1 TMTC3 0 0 184 183 1 1
XBP1 CCNB1 0 0 216 236 1 1
XBP1 ANXA5 0 0 505 549 1 2
XBP1 HSPD1 0 0 108 244 1 1
XBP1 RPS3 0 0 74 171 1 1
XBP1 FBXO32 0 0 170 169 1 2
XBP1 TRPC1 0 0 438 438 1 1
XBP1 WHSC1 0 0 194 194 1 1
XBP1 FOXM1 0 0 287 301 1 1
XBP1 ZBTB20 0 0 181 203 1 1
XBP1 NFKB1 0 0 202 202 1 2
XBP1 KLF6 0 0 125 198 1 1
XBP1 UHRF1 0 0 81 177 1 1
XBP1 RPL13 800 0 0 800 1 1
XBP1 SPRYD4 0 0 90 238 1 1
XBP1 TUBB4A 0 0 193 193 1 1
XBP1 BCL2L1 0 0 469 469 1 2
XBP1 RELA 0 0 310 329 1 2
XBP1 P2RY8 0 0 73 184 1 1
XBP1 PIK3R4 0 0 182 181 1 2
XBP1 ELF5 0 0 62 206 1 1
XBP1 STAT4 0 0 195 213 1 1
XBP1 ITPR2 0 0 179 185 1 1
XBP1 TNFSF15 0 0 157 158 1 1
XBP1 GABARAPL2 0 0 261 279 1 2
XBP1 RD3 0 0 218 218 1 1
XBP1 MOGS 0 0 234 274 1 1
XBP1 HAMP 0 0 134 164 1 1
XBP1 SMG1 0 0 134 193 1 1
XBP1 PGLYRP2 0 0 0 426 1 1
XBP1 TCF7L2 0 0 134 220 1 1
XBP1 MAP2K7 0 0 260 268 1 1
XBP1 NOS2 0 0 118 158 1 2
XBP1 ELF1 0 0 45 212 1 1
XBP1 EBF1 0 0 213 295 1 1
XBP1 SPDEF 0 0 293 310 1 1
XBP1 ABL1 0 0 113 166 1 1
XBP1 CD22 0 0 307 307 1 1
XBP1 TLR4 0 0 512 521 1 2
XBP1 SMAD2 0 0 194 194 1 2
XBP1 DUSP5 0 0 83 294 1 1
XBP1 TENM4 0 0 150 282 1 1
XBP1 GAPDH 0 0 611 624 1 2
XBP1 EGR3 0 0 145 159 1 1
XBP1 HDGF 117 900 45 908 1 1
XBP1 ATG14 0 0 217 217 1 2
XBP1 DAD1 0 0 156 163 1 1
XBP1 PDIA3 0 0 556 802 1 1
XBP1 LPIN1 0 0 181 181 1 2
XBP1 HLA-DRA 0 0 151 150 1 1
XBP1 TFG 0 0 57 155 1 1
XBP1 UGP2 0 0 53 212 1 1
XBP1 CARD11 0 0 133 327 1 1
XBP1 DNAJB9 0 900 757 980 1 2
XBP1 MAN2A2 0 0 0 379 1 1
XBP1 FOXC1 0 0 202 218 1 1
XBP1 SIGMAR1 0 0 294 309 1 1
XBP1 NOD1 0 0 235 235 1 2
XBP1 ACADVL 0 900 0 901 1 1
XBP1 CD86 0 0 283 282 1 1
XBP1 BCL2L15 0 0 112 167 1 1
XBP1 TBPL1 0 800 0 800 1 1
XBP1 SEC62 0 0 236 236 1 1
XBP1 GALE 0 0 242 381 1 1
XBP1 CDC25A 0 0 67 196 1 1
XBP1 DNAJC10 0 0 422 492 1 1
XBP1 CERS6 0 0 150 282 1 1
XBP1 TLR2 0 0 391 404 1 2
XBP1 RPL23A 800 0 45 800 1 1
XBP1 PMAIP1 0 0 458 457 1 2
XBP1 ANKRD45 0 0 0 522 1 1
XBP1 DUSP1 0 0 181 271 1 1
XBP1 EMC1 0 0 59 159 1 1
XBP1 MAPK11 0 0 81 291 1 1
XBP1 WARS 0 0 211 230 1 1
XBP1 ERLIN2 0 0 137 170 1 1
XBP1 CDKN2C 0 0 107 196 1 1
XBP1 ATXN3 0 0 180 179 1 2
XBP1 LRRK2 0 0 325 342 1 2
XBP1 PTF1A 0 0 107 155 1 1
XBP1 SDC1 0 0 619 637 1 1
XBP1 THBS1 0 0 157 156 1 1
XBP1 BECN1 0 0 519 602 1 2
XBP1 MAPT 0 0 171 171 1 2
XBP1 STT3A 0 0 134 237 1 1
XBP1 OLR1 0 0 168 167 1 2
XBP1 IL2 0 0 287 286 1 1
XBP1 DERL1 270 0 391 636 1 1
XBP1 TLR6 0 0 74 171 1 1
XBP1 RPS14 800 0 0 800 1 1
XBP1 KRAS 0 0 210 231 1 2
XBP1 FOXO1 0 0 940 941 1 2
XBP1 EPAS1 0 0 91 184 1 2
XBP1 RPS15A 800 0 0 800 1 1
XBP1 GPX2 0 0 143 161 1 1
XBP1 SOD2 0 0 287 302 1 2
XBP1 TFE3 0 0 66 162 1 2
XBP1 HSPA5 282 0 878 974 1 2
XBP1 NRAS 0 0 120 152 1 1
XBP1 SLC35B1 0 0 97 172 1 1
XBP1 MLST8 0 0 123 172 1 1
XBP1 RPS21 800 0 0 800 1 1
XBP1 HAX1 0 0 306 306 1 1
XBP1 ZNF346 0 0 0 153 1 1
XBP1 LMO2 0 0 151 198 1 1
XBP1 RXRA 0 0 421 443 1 1
XBP1 SRP14 800 0 44 800 1 1
XBP1 STAT5A 0 0 240 313 1 1
XBP1 ANGPTL4 0 0 150 171 1 1
XBP1 MLEC 0 0 103 225 1 1
XBP1 RPS11 800 0 0 852 1 1
XBP1 UFSP1 0 0 124 179 1 1
XBP1 HM13 385 0 63 430 1 1
XBP1 FOS 270 0 389 562 1 2
XBP1 MAN2B1 0 0 0 302 1 1
XBP1 FASLG 0 0 203 203 1 1
XBP1 NELFB 0 0 89 164 1 1
XBP1 RPL10 800 0 0 800 1 1
XBP1 GAS7 0 0 414 414 1 1
XBP1 SOCS3 0 0 234 234 1 1
XBP1 ERO1LB 0 0 498 673 1 1
XBP1 CRYAB 0 0 124 178 1 2
XBP1 PRDM1 0 0 708 779 1 1
XBP1 MSRB1 0 0 61 206 1 1
XBP1 HDAC1 0 0 243 242 1 2
XBP1 CSF1 0 0 158 157 1 1
XBP1 RIPK1 0 0 234 270 1 2
XBP1 TG 0 0 220 220 1 1
XBP1 PLA2G4B 0 900 0 900 1 1
XBP1 NOD2 0 0 578 578 1 2
XBP1 CIITA 0 0 284 284 1 1
XBP1 PDIA4 0 0 615 706 1 1
XBP1 ATG16L1 0 0 564 586 1 2
XBP1 TXNRD1 0 0 167 173 1 1
XBP1 DHFR 0 0 139 156 1 1
XBP1 CEBPB 0 0 620 652 1 2
XBP1 PGM3 0 0 108 158 1 1
XBP1 INSRR 0 0 0 159 1 1
XBP1 ARFGAP1 0 900 0 900 1 1
XBP1 STARD10 0 0 143 196 1 1
XBP1 NPLOC4 0 0 269 285 1 1
XBP1 KIN 0 0 0 405 1 1
XBP1 CHUK 0 0 235 254 1 1
XBP1 CUL3 0 0 142 282 1 2
XBP1 UNC119 0 0 203 252 1 1
XBP1 KLF2 0 0 150 183 1 1
XBP1 PNPLA3 0 0 135 194 1 1
XBP1 CDKN2A 0 0 209 209 1 2
XBP1 CASP4 0 0 519 556 1 2
XBP1 PCNXL3 0 0 0 152 1 1
XBP1 SOCS2 0 0 112 165 1 1
XBP1 UNC13B 0 0 134 162 1 1
XBP1 RPS27A 800 0 48 801 1 1
XBP1 FABP4 0 0 216 216 1 1
XBP1 ADPGK 0 0 71 162 1 1
XBP1 ITGAX 0 0 264 264 1 1
XBP1 ZNF366 0 0 82 246 1 1
XBP1 RPS4X 800 0 0 800 1 1
XBP1 GSK3B 0 0 202 270 1 2
XBP1 RPS15 800 0 0 812 1 1
XBP1 HARS 0 0 48 150 1 1
XBP1 MZB1 0 0 322 321 1 1
XBP1 CYBB 0 0 298 298 1 2
XBP1 CD28 0 0 211 211 1 1
XBP1 CD5 0 0 181 181 1 1
XBP1 BHLHA15 0 0 437 449 1 1
XBP1 SMCO3 0 0 164 163 1 1
XBP1 PPIA 0 0 209 213 1 1
XBP1 PSMA5 270 0 0 270 1 1
XBP1 TNFSF13B 0 0 370 370 1 1
XBP1 ETV7 0 0 56 201 1 1
XBP1 HSPA4L 0 0 134 206 1 1
XBP1 RPL31 800 0 0 800 1 1
XBP1 ATG12 0 0 409 463 1 2
XBP1 KDELR3 0 900 118 911 1 1
XBP1 REN 0 0 134 157 1 1
XBP1 SULT1A3 0 900 0 900 1 1
XBP1 TNFRSF10B 0 0 469 488 1 2
XBP1 UFSP2 0 0 127 214 1 1
XBP1 IL13 0 0 224 224 1 2
XBP1 TMEM259 0 0 166 196 1 1
XBP1 TBC1D9 0 0 166 165 1 1
XBP1 HADH 0 0 66 163 1 1
XBP1 TUB 0 0 358 358 1 1
XBP1 AICDA 0 0 517 534 1 1
XBP1 PSMB9 0 0 144 150 1 1
XBP1 PTGS2 0 0 288 288 1 2
XBP1 ARID3A 0 0 148 170 1 1
XBP1 NQO1 0 0 252 257 1 2
XBP1 RPSA 800 0 45 800 1 1
XBP1 ERBB3 0 0 193 193 1 1
XBP1 PDIA6 0 900 503 957 1 1
XBP1 CASP3 0 0 661 694 1 2
XBP1 RPS10-NUDT3 800 0 0 800 1 1
XBP1 TMEM38B 0 0 134 284 1 1
XBP1 UFL1 0 0 232 299 1 1
XBP1 CXCL1 0 0 235 242 1 2
XBP1 GFPT1 0 900 294 938 1 1
XBP1 UBE2V1 298 0 0 298 1 1
XBP1 TRIB3 0 0 518 541 1 2
XBP1 ATG101 0 0 193 214 1 2
XBP1 HSPB8 0 0 186 186 1 2
XBP1 REL 0 0 248 252 1 2
XBP1 NLRP3 0 0 336 336 1 2
XBP1 OS9 0 0 393 419 1 1
XBP1 HSPA1B 0 0 163 242 1 1
XBP1 ELF3 0 0 125 260 1 1
XBP1 VEGFA 0 0 392 392 1 2
XBP1 IRF4 0 0 653 672 1 1
XBP1 FSD1L 0 0 150 235 1 1
XBP1 MAPK7 0 0 107 176 1 1
XBP1 GABARAP 0 0 219 255 1 2
XBP1 ID3 0 0 182 181 1 1
XBP1 RPS29 800 0 0 800 1 1
XBP1 GJA8 0 0 103 200 1 1
XBP1 PTEN 0 0 325 333 1 2
XBP1 SLC9C2 0 0 0 522 1 1
XBP1 MAGEA4 0 0 0 188 1 1
XBP1 SRP9 800 0 46 801 1 1
XBP1 HECW2 0 0 0 177 1 1
XBP1 WIPI1 0 900 241 923 1 2
XBP1 DNM1L 0 0 205 205 1 2
XBP1 MYOD1 0 0 181 181 1 1
XBP1 BHLHE41 0 0 141 173 1 1
XBP1 GAPDHS 0 0 0 189 1 1
XBP1 COL10A1 0 0 164 178 1 1
XBP1 SCARA3 0 0 263 279 1 1
XBP1 ATXN1L 0 0 0 162 1 1
XBP1 SIL1 0 0 294 309 1 1
XBP1 HCFC2 0 0 0 729 1 1
XBP1 GOSR2 0 900 0 900 1 1
XBP1 RPS20 800 0 54 802 1 1
XBP1 ZC3H12A 0 0 113 162 1 1
XBP1 TCF4 0 0 297 324 1 1
XBP1 RTCA 0 0 342 499 1 1
XBP1 AMBRA1 0 0 150 169 1 2
XBP1 WT1 0 0 142 156 1 1
XBP1 MAN1A2 0 0 54 199 1 1
XBP1 NFE2L1 0 0 181 511 1 1
XBP1 CCNA1 0 0 167 167 1 1
XBP1 COMMD3-BMI1 0 0 134 152 1 1
XBP1 KIT 0 0 209 209 1 2
XBP1 NFKBIA 0 0 374 374 1 2
XBP1 S1PR1 0 0 138 157 1 1
XBP1 RTCB 0 0 651 798 1 1
XBP1 LEP 0 0 391 401 1 1
XBP1 SYK 0 0 176 197 1 2
XBP1 RPL34 800 0 0 800 1 1
XBP1 IL21R 0 0 193 223 1 1
XBP1 DNAJC1 0 0 181 181 1 1
XBP1 RABGGTA 0 0 0 250 1 1
XBP1 MAPK14 0 0 210 391 1 2
XBP1 POU4F3 0 0 0 179 1 1
XBP1 MAPK10 0 0 155 294 1 2
XBP1 AKR7A2 0 0 62 220 1 1
XBP1 BAG1 0 0 182 181 1 2
XBP1 CD79A 0 0 306 306 1 1
XBP1 UBA52 800 0 0 800 1 1
XBP1 FKBP2 0 0 415 427 1 1
XBP1 UCP1 0 0 223 223 1 2
XBP1 FAM134B 0 0 180 179 1 1
XBP1 RPS24 800 0 44 811 1 1
XBP1 SREBF1 0 0 640 663 1 1
XBP1 SLC27A2 0 0 108 154 1 1
XBP1 RPL37 800 0 0 800 1 1
XBP1 PREB 0 900 81 908 1 1
XBP1 CEPT1 0 0 166 165 1 1
XBP1 PON2 0 0 137 160 1 1
XBP1 IL23A 0 0 180 179 1 1
XBP1 CTSD 0 0 233 256 1 2
XBP1 SLC4A4 0 0 357 357 1 1
XBP1 ATM 0 0 253 260 1 2
XBP1 SHC1 0 900 105 907 1 1
XBP1 COL4A3BP 0 0 143 177 1 1
XBP1 RPS13 800 0 0 800 1 1
XBP1 AGRP 0 0 181 181 1 1
XBP1 ELL2 0 0 235 242 1 1
XBP1 TGFBR2 0 0 138 160 1 1
XBP1 TJP1 0 0 166 165 1 1
XBP1 ATG7 0 0 469 584 1 2
XBP1 FOSB 0 0 116 167 1 1
XBP1 PPP1R15B 0 0 401 412 1 1
XBP1 IKZF1 0 0 210 305 1 1
XBP1 CNPY2 0 0 170 257 1 1
XBP1 RPL21 800 0 0 800 1 1
XBP1 GDF15 0 0 181 200 1 1
XBP1 FOSL2 0 0 150 199 1 1
XBP1 RPL38 800 0 0 800 1 1
XBP1 NR1H4 0 0 203 217 1 1
XBP1 RCL1 0 0 0 270 1 1
XBP1 ACTG1 0 0 268 301 1 1
XBP1 GFAP 0 0 157 156 1 2
XBP1 SLC30A7 0 0 66 160 1 1
XBP1 SNAI1 0 0 181 186 1 1
XBP1 IL10 0 0 403 410 1 2
XBP1 RPS3A 800 0 66 824 1 1
XBP1 PPARGC1B 0 0 118 151 1 1
XBP1 COL1A1 0 0 157 156 1 2
XBP1 DERL3 0 0 503 556 1 1
XBP1 ATG10 0 0 218 239 1 2
XBP1 RRBP1 0 0 74 161 1 1
XBP1 RT14 0 0 424 512 1 1
XBP1 HSPB1 0 0 324 328 1 2
XBP1 VAV1 0 0 95 151 1 1
XBP1 TET2 0 0 75 171 1 2
XBP1 HERPUD2 0 0 160 203 1 1
XBP1 HSPB2 0 0 314 319 1 1
XBP1 UFC1 0 0 107 218 1 1
XBP1 ISG15 0 0 157 156 1 2
XBP1 EIF2A 0 0 520 658 1 2
XBP1 SMIM4 0 0 0 213 1 1
XBP1 MAP1LC3B 0 0 466 488 1 2
XBP1 MATN3 0 0 218 218 1 1
XBP1 SMG6 0 0 155 247 1 1
XBP1 TRAM2 0 0 127 223 1 1
XBP1 RPL18A 800 0 0 800 1 1
XBP1 ELANE 0 0 122 202 1 1
XBP1 LILRB3 0 0 327 327 1 1
XBP1 RPS18 800 0 60 803 1 1
XBP1 GPX3 0 0 357 357 1 1
XBP1 POU2F2 0 0 181 201 1 1
XBP1 RPL5 800 0 46 801 1 1
XBP1 SEL1L 0 0 504 568 1 1
XBP1 CA12 0 0 181 181 1 1
XBP1 SOD3 0 0 95 151 1 1
XBP1 NUCB1 0 0 159 180 1 1
XBP1 CDC25B 0 0 75 203 1 1
XBP1 TBX21 0 0 244 243 1 1
XBP1 ULK1 0 0 323 324 1 2
XBP1 RPS23 800 0 0 800 1 1
XBP1 NCAM1 0 0 113 174 1 1
XBP1 FN1 0 0 249 248 1 2
XBP1 TBP 0 800 265 846 1 1
XBP1 SURF4 0 0 185 269 1 1
XBP1 GPX1 0 0 260 274 1 1
XBP1 RARA 0 0 216 229 1 2
XBP1 IKBKG 0 0 245 244 1 1
XBP1 RAG2 0 0 398 398 1 1
XBP1 CCR7 0 0 180 179 1 1
XBP1 DDX11 0 900 0 900 1 1
XBP1 CXCR5 0 0 251 266 1 1
XBP1 AKT3 0 0 123 176 1 2
XBP1 SEC22B 0 0 136 170 1 1
XBP1 SEC61B 800 0 324 870 1 1
XBP1 ACOX1 0 0 194 195 1 1
XBP1 CTSB 0 0 194 194 1 2
XBP1 NOX1 0 0 140 159 1 1
XBP1 LMNB1 0 0 157 163 1 1
XBP1 SPI1 0 0 270 298 1 1
XBP1 CST7 0 0 86 225 1 1
XBP1 PLIN2 0 0 264 280 1 2
XBP1 SIRT1 0 0 390 409 1 2
XBP1 ELF4 0 0 57 222 1 1
XBP1 MCL1 0 0 459 476 1 2
XBP1 NKX2-3 0 0 180 194 1 2
XBP1 PSMC5 270 0 96 331 1 1
XBP1 DKK4 0 0 0 189 1 1
XBP1 OPTN 0 0 202 231 1 2
XBP1 MAP3K5 0 0 661 713 1 1
XBP1 ITGAM 0 0 284 284 1 1
XBP1 GATA2 0 0 134 193 1 1
XBP1 BACE1 0 0 210 210 1 2
XBP1 PCNXL2 0 0 0 152 1 1
XBP1 POU2AF1 0 0 522 525 1 1
XBP1 LYN 0 0 150 172 1 1
XBP1 IRF5 0 0 162 161 1 1
XBP1 TXNDC5 0 0 341 412 1 1
XBP1 HMGB1 0 0 235 241 1 2
XBP1 IFNB1 0 0 373 373 1 1
XBP1 ESR1 270 0 827 876 1 2
XBP1 PIM2 0 0 134 154 1 1
XBP1 ATG5 0 0 518 649 1 2
XBP1 CALCOCO2 0 0 193 193 1 2
XBP1 UGGT1 0 0 295 339 1 1
XBP1 TBC1D23 0 0 148 201 1 1
XBP1 HSF4 0 0 0 150 1 1
XBP1 MT-ND1 0 0 46 153 1 1
XBP1 LGR5 0 0 213 213 1 1
XBP1 PDIA5 0 900 298 931 1 1
XBP1 CXCR3 0 0 138 155 1 1
XBP1 RPL27A 800 0 0 800 1 1
XBP1 STAT2 0 0 146 294 1 1
XBP1 UGGT2 0 0 108 163 1 1
XBP1 KDELR2 0 0 108 199 1 1
XBP1 RPL23 800 0 0 800 1 1
XBP1 FUS 0 0 171 171 1 2
XBP1 UFM1 0 0 246 340 1 1
XBP1 PTPN1 0 0 325 325 1 1
XBP1 MYBL2 0 0 145 177 1 1
XBP1 MANF 0 0 504 716 1 1
XBP1 IRF1 0 0 283 288 1 2
XBP1 NFYC 270 900 134 932 1 1
XBP1 C22orf29 0 0 322 321 1 1
XBP1 HSPA2 0 0 97 184 1 1
XBP1 COL8A1 0 0 0 208 1 1
XBP1 HSPA13 0 0 119 202 1 1
XBP1 SEMA4D 0 0 0 189 1 1
XBP1 YBX1 0 0 134 225 1 1
XBP1 NBR1 0 0 207 207 1 2
XBP1 TNF 0 0 518 544 1 2
XBP1 MLX 0 0 123 156 1 1
XBP1 ARNT2 0 0 132 167 1 1
XBP1 PIK3R2 0 0 872 872 1 1
XBP1 CASP2 0 0 458 481 1 1
XBP1 TRAP1 0 0 112 209 1 2
XBP1 CCDC102B 229 0 0 228 1 1
XBP1 ANKRD26 0 0 398 398 1 1
XBP1 UBAC2 0 0 108 152 1 1
XBP1 ANKRD1 0 0 100 156 1 1
XBP1 BDNF 0 0 251 250 1 2
XBP1 SLC1A5 0 0 134 165 1 1
XBP1 RPL18 800 0 43 800 1 1
XBP1 CD44 0 0 267 267 1 2
XBP1 MEF2C 0 0 132 170 1 1
XBP1 VAPB 0 0 252 298 1 1
XBP1 NRIP1 0 0 181 181 1 1
XBP1 VCL 0 0 145 163 1 1
XBP1 UBL3 0 0 0 186 1 1
XBP1 RCAN1 0 0 134 179 1 2
XBP1 FIS1 0 0 207 207 1 2
XBP1 NAT8 0 0 165 165 1 1
XBP1 MMP7 0 0 134 153 1 1
XBP1 ERCC3 0 0 0 369 1 1
XBP1 POU2F1 0 0 142 190 1 1
XBP1 EEF2 0 0 150 169 1 2
XBP1 USP14 0 0 400 412 1 2
XBP1 ZFAND5 0 0 66 166 1 1
XBP1 RPLP0 800 0 150 824 1 1
XBP1 PPP1R15A 0 0 801 861 1 2
XBP1 STT3B 0 0 107 177 1 1
XBP1 NFAT5 0 0 116 156 1 1
XBP1 TFAP2C 0 0 146 294 1 1
XBP1 CKAP4 0 0 144 174 1 1
XBP1 IL23R 0 0 213 213 1 1
XBP1 RBFOX3 0 0 142 164 1 1
XBP1 SLC7A11 0 0 244 243 1 2
XBP1 CBSL 0 0 150 169 1 1
XBP1 TNFAIP3 0 0 195 211 1 2
XBP1 SRP54 800 0 113 819 1 1
XBP1 GCG 0 0 321 321 1 1
XBP1 TNNT2 0 0 0 207 1 1
XBP1 SPN 0 0 193 193 1 1
XBP1 ATG4B 0 0 184 185 1 2
XBP1 EDEM1 0 900 769 983 1 2
XBP1 NFKB2 0 0 167 167 1 1
XBP1 GSTP1 0 0 117 153 1 1
XBP1 IFNAR1 0 0 154 153 1 1
XBP1 CCND2 0 0 218 220 1 1
XBP1 TFRC 0 0 143 682 1 1
XBP1 ENSG00000272980 0 0 174 191 1 1
XBP1 TFAP2A 0 0 59 222 1 1
XBP1 IL5 0 0 217 217 1 1
XBP1 HECW1 0 0 45 243 1 1
XBP1 FKBP1C 0 0 150 178 1 1
XBP1 TXNIP 0 0 427 435 1 2
XBP1 BCL2A1 0 0 203 258 1 1
XBP1 RELB 0 0 195 195 1 2
XBP1 RPL7A 800 0 0 800 1 1
XBP1 UBE2J1 0 0 264 280 1 1
XBP1 C1QTNF6 0 0 193 193 1 1
XBP1 SDF2L1 0 0 391 427 1 1
XBP1 RAB7A 0 0 184 201 1 2
XBP1 BCAP31 0 0 310 336 1 1
XBP1 CXCL3 0 0 180 187 1 1
XBP1 FGF2 0 0 213 213 1 2
XBP1 PRDX4 0 0 170 219 1 1
XBP1 GCSAM 0 0 155 154 1 1
XBP1 SEC61A2 0 0 68 156 1 1
XBP1 ATF3 0 0 631 673 1 2
XBP1 RETN 0 0 131 150 1 1
XBP1 RPS10 800 0 0 800 1 1
XBP1 GADD45A 0 0 288 288 1 1
XBP1 PKM 0 0 147 162 1 1
XBP1 SRPRB 0 900 143 919 1 1
XBP1 BTK 0 0 219 239 1 1
XBP1 ARNTL 0 0 183 200 1 1
XBP1 CCND3 0 0 165 165 1 1
XBP1 ULBP2 0 0 66 168 1 1
XBP1 UVRAG 0 0 231 231 1 2
XBP1 WDFY3 0 0 123 155 1 2
XBP1 CSF1R 0 0 95 180 1 1
XBP1 APOB 0 0 321 333 1 2
XBP1 IGF1 0 0 325 325 1 2
XBP1 MAPK1 0 0 145 211 1 2
XBP1 ANAPC2 0 0 66 210 1 1
XBP1 IRF7 0 0 219 219 1 1
XBP1 SRP68 800 0 75 807 1 1
XBP1 ETV6 0 0 48 194 1 1
XBP1 ZBTB32 0 0 146 209 1 1
XBP1 CRBN 0 0 195 195 1 1
XBP1 SERPINE1 0 0 146 165 1 1
XBP1 AHR 0 0 195 195 1 2
XBP1 CDK1 0 0 193 193 1 2
XBP1 NCOR1 0 0 134 150 1 1
XBP1 EIF4E 0 0 282 290 1 2
XBP1 MUC1 0 0 171 195 1 1
XBP1 PGR 0 0 358 369 1 1
XBP1 KAT2B 270 0 113 325 1 1
XBP1 RPS6KB1 0 0 347 387 1 2
XBP1 RPS9 800 0 55 811 1 1
XBP1 LOX 0 0 217 217 1 2
XBP1 HSPA9 0 0 294 381 1 1
XBP1 IRS1 0 0 459 471 1 2
XBP1 SGK1 0 0 150 187 1 2
XBP1 HMGCR 0 0 229 249 1 1
XBP1 GREB1 0 0 423 427 1 1
XBP1 STIM1 0 0 167 167 1 2
XBP1 ADRA2C 0 0 0 161 1 1
XBP1 CD19 0 0 402 402 1 1
XBP1 BCL2L2 0 0 213 213 1 1
XBP1 TXNDC11 0 0 134 283 1 1
XBP1 UBE2I 270 0 450 625 1 1
XBP1 BLNK 0 0 306 316 1 1
XBP1 QSOX1 0 0 113 168 1 1
XBP1 NCF1 0 0 155 154 1 1
XBP1 JUND 0 0 141 209 1 1
XBP1 KXD1 0 0 0 398 1 1
XBP1 NOS3 0 0 241 240 1 2
XBP1 CCND1 0 0 419 418 1 2
XBP1 APEH 0 0 204 204 1 1
XBP1 SREBF2 0 0 391 423 1 1
XBP1 CD274 0 0 203 203 1 2
XBP1 HSF2 0 0 0 189 1 1
XBP1 CSF2RB 0 0 91 173 1 1
XBP1 SRPR 0 900 124 912 1 1
XBP1 PRKAA1 0 0 122 211 1 2
XBP1 PSMA7 270 0 53 279 1 1
XBP1 GBA 0 0 150 243 1 1
XBP1 ATP2A2 0 0 243 365 1 1
XBP1 SSR3 0 0 94 217 1 1
XBP1 UAP1 0 0 157 192 1 1
XBP1 SLC27A1 0 0 150 176 1 1
XBP1 DNAJB2 0 0 169 226 1 1
XBP1 CTLA4 0 0 284 284 1 2
XBP1 CROCC 130 0 0 225 1 1
XBP1 EHF 0 0 0 189 1 1
XBP1 LDLR 0 0 216 231 1 2
XBP1 LPCAT3 0 0 124 161 1 1
XBP1 GNB2L1 800 0 220 837 1 1
XBP1 FOXA2 0 0 134 188 1 1
XBP1 CD38 0 0 394 394 1 2
XBP1 GNPNAT1 0 0 181 219 1 1
XBP1 MYB 0 0 202 217 1 1
XBP1 PTPN2 0 0 218 218 1 2
XBP1 BAK1 0 0 306 306 1 2
XBP1 SPRY1 0 0 68 161 1 1
XBP1 ADD1 0 900 0 900 1 1
XBP1 HPRT1 0 0 294 295 1 1
XBP1 RNASEL 0 0 288 366 1 1
XBP1 AARS 0 0 140 301 1 1
XBP1 DDIT4 0 0 321 321 1 2
XBP1 RHEB 0 0 240 253 1 2
XBP1 ATF7 0 0 132 182 1 1
XBP1 FDFT1 0 0 134 168 1 1
XBP1 STXBP3 0 0 67 269 1 1
XBP1 CDIPT 0 0 74 186 1 1
XBP1 TXN 0 0 334 373 1 1
XBP1 CANX 282 0 668 855 1 2
XBP1 HRK 0 0 184 183 1 1
XBP1 SPINK1 0 0 254 329 1 1
XBP1 PECAM1 0 0 171 171 1 1
XBP1 CAT 0 0 394 453 1 2
XBP1 GFI1 0 0 193 206 1 1
XBP1 TBK1 0 0 201 221 1 2
XBP1 MGST1 0 0 134 242 1 1
XBP1 HMOX1 0 0 450 450 1 2
XBP1 FOXP3 0 0 264 279 1 2
XBP1 MITF 0 0 134 248 1 2
XBP1 IARS 0 0 137 159 1 1
XBP1 JAK1 0 0 193 213 1 2
XBP1 KDR 0 0 407 407 1 2
XBP1 SKP1 0 0 97 298 1 2
XBP1 EIF2S1 0 0 831 923 1 2
XBP1 RPL11 800 0 0 800 1 1
XBP1 TBPL2 0 800 0 800 1 1
XBP1 ATF6B 271 0 540 868 1 1
XBP1 YY1 0 0 218 278 1 1
XBP1 NFATC2 0 0 61 171 1 1
XBP1 TGFB1 0 0 113 168 1 2
XBP1 KRT19 0 0 163 183 1 1
XBP1 VDAC1 0 0 398 398 1 2
XBP1 TSC2 0 0 286 312 1 2
XBP1 MC4R 0 0 111 154 1 1
XBP1 RAB7B 0 0 174 192 1 1
XBP1 STAT5B 0 0 230 304 1 1
XBP1 SCGB1A1 0 0 276 276 1 1
XBP1 BNIP3L 0 0 160 171 1 2
XBP1 GLUL 0 0 154 153 1 1
XBP1 CDKN1B 0 0 181 181 1 2
XBP1 MAP3K6 0 0 0 189 1 1
XBP1 PRKCD 0 0 171 171 1 2
XBP1 CTCF 0 0 155 183 1 1
XBP1 OXCT1 0 0 67 170 1 1
XBP1 CUX2 0 0 415 463 1 1
XBP1 FOXO3 0 0 283 674 1 2
XBP1 SLC2A4 0 0 212 213 1 1
XBP1 APOE 0 0 296 296 1 2
XBP1 TNFSF11 0 0 155 154 1 2
XBP1 DGAT2 0 0 377 391 1 1
XBP1 LRP8 0 0 53 199 1 1
XBP1 RAG1 0 0 173 173 1 1
XBP1 RPS8 800 0 0 800 1 1
XBP1 IRF8 0 0 370 370 1 1
XBP1 SCD 0 0 393 403 1 1
XBP1 VIMP 0 0 310 367 1 1
XBP1 DKK1 0 0 145 175 1 1
XBP1 SRC 0 0 271 289 1 2
XBP1 CD93 0 0 150 208 1 1
XBP1 CADM1 0 0 181 181 1 1
XBP1 TCL1A 0 0 447 528 1 1
XBP1 PSMB5 0 0 233 232 1 1
XBP1 DNAJB11 0 900 544 958 1 1
XBP1 MAN1C1 0 0 96 158 1 1
XBP1 ATG3 0 0 260 270 1 2
XBP1 DNAJB1 0 0 455 481 1 2
XBP1 HARS2 0 0 53 154 1 1
XBP1 JDP2 0 0 105 157 1 1
XBP1 BIRC6 0 0 122 193 1 1
XBP1 TLR3 0 0 265 265 1 2
XBP1 RTN3 0 0 173 179 1 1
XBP1 TP53INP1 0 0 211 211 1 2
XBP1 SRXN1 0 0 166 165 1 1
XBP1 ACLY 0 0 229 228 1 1
XBP1 STAT6 0 0 286 349 1 1
XBP1 HNF4A 0 0 284 284 1 1
XBP1 POU4F1 0 0 66 201 1 1
XBP1 RNF139 270 0 337 537 1 1
XBP1 EIF2AK3 0 0 857 937 1 2
XBP1 CCK 0 0 140 170 1 1
XBP1 CTRC 0 0 219 268 1 1
XBP1 BIRC5 0 0 141 181 1 2
XBP1 CLGN 0 0 0 429 1 1
XBP1 SIRT4 0 0 193 194 1 1
XBP1 GSK3A 0 900 0 904 1 1
XBP1 IL24 0 0 165 165 1 2
XBP1 RPL29 800 0 47 801 1 1
XBP1 PINK1 0 0 264 373 1 2
XBP1 BCL6 0 0 601 625 1 1
XBP1 PCNXL4 0 0 0 152 1 1
XBP1 SSR2 0 0 150 242 1 1
XBP1 CERS4 0 0 93 155 1 1
XBP1 PHGDH 0 0 204 233 1 1
XBP1 GPT 0 0 294 294 1 1
XBP1 ID2 0 0 150 168 1 1
XBP1 CXCL10 0 0 243 242 1 2
XBP1 RTN4 0 0 170 176 1 1
XBP1 EIF4EBP1 0 0 324 350 1 2
XBP1 KRT18 0 0 215 239 1 1
XBP1 HSP90AB1 0 0 136 384 1 2
XBP1 FOXO4 0 0 484 495 1 1
XBP1 GPR183 0 0 181 181 1 1
XBP1 CREM 0 0 144 197 1 1
XBP1 TLR9 0 0 320 319 1 2
XBP1 GFPT2 0 0 150 256 1 1
XBP1 STC2 0 0 253 252 1 1
XBP1 IL6ST 0 0 182 199 1 1
XBP1 MAP3K1 0 0 134 151 1 1
XBP1 NR1I2 0 0 134 171 1 1
XBP1 VLDLR 0 0 193 208 1 1
XBP1 NR5A2 0 0 103 164 1 1
XBP1 BBC3 0 0 269 269 1 2
XBP1 C19orf10 0 900 0 902 1 1
XBP1 TAP1 0 0 136 158 1 1
XBP1 IRF3 0 0 293 293 1 2
XBP1 YIPF5 0 0 236 255 1 1
XBP1 CPA1 0 0 141 163 1 1
XBP1 CR2 0 0 271 281 1 1
XBP1 DMXL1 0 0 261 261 1 1
XBP1 ARG2 0 0 171 171 1 1
XBP1 ERBB2 0 0 370 377 1 2
XBP1 CD34 0 0 154 153 1 2
XBP1 NGF 0 0 165 180 1 2
XBP1 ENSG00000274276 0 0 150 169 1 1
XBP1 ERP29 0 0 392 392 1 1
XBP1 ST8SIA4 0 0 325 325 1 1
XBP1 MKI67 0 0 183 219 1 2
XBP1 CLPP 0 0 150 212 1 1
XBP1 KCNJ5 0 0 307 307 1 1
XBP1 CSF2 0 0 235 235 1 1
XBP1 PPARG 0 0 455 465 1 2
XBP1 MARCH6 0 0 182 188 1 1
XBP1 TGFB2 0 0 124 158 1 1
XBP1 SLC39A7 0 0 122 201 1 1
XBP1 CAPN1 0 0 165 183 1 2
XBP1 CPT1A 0 0 230 246 1 1
XBP1 SPIB 0 0 378 378 1 1
XBP1 TMED2 0 0 116 174 1 1
XBP1 AKT1 0 0 611 635 1 2
XBP1 MAP3K15 0 0 0 189 1 1
XBP1 SPPL2B 0 0 57 244 1 1
XBP1 IFIT3 0 0 123 155 1 1
XBP1 VCAM1 0 0 233 232 1 1
XBP1 RPL26 800 0 47 801 1 1
XBP1 SLC30A5 0 0 124 268 1 1
XBP1 ATF4 0 0 831 907 1 2
XBP1 CD4 0 0 391 390 1 2
XBP1 HSPH1 0 0 140 212 1 1
XBP1 DERL2 0 0 452 543 1 1
XBP1 CA9 0 0 138 156 1 1
XBP1 MBTPS1 0 0 651 660 1 1
XBP1 ATP2A3 0 0 202 330 1 1
XBP1 SAFB 0 0 62 160 1 1
XBP1 FOXA1 0 0 503 551 1 1
XBP1 FAS 0 0 246 253 1 2
XBP1 CPE 0 0 166 172 1 1
XBP1 UBA5 0 0 193 258 1 1
XBP1 SUMO1 0 0 155 185 1 1
XBP1 PRSS46 0 0 228 237 1 1
XBP1 KLF4 0 0 217 230 1 2
XBP1 SATB1 0 0 127 158 1 1
XBP1 IKBKB 0 0 296 314 1 2
XBP1 ATF6 458 900 939 998 1 2
XBP1 SDF2 0 0 150 206 1 1
XBP1 CALR3 0 0 0 359 1 1
XBP1 AARS2 0 0 68 229 1 1
XBP1 CREB3L4 0 0 460 464 1 1
XBP1 ACACB 0 0 210 224 1 1
XBP1 RPL35 800 0 0 800 1 1
XBP1 PSPH 0 0 90 171 1 1
XBP1 RUNX2 0 0 500 500 1 2
XBP1 TMED10 0 0 95 172 1 1
XBP1 CEBPG 0 0 208 454 1 1
XBP1 VMP1 0 0 124 205 1 2
XBP1 PPP2R4 0 0 217 217 1 1
XBP1 XIAP 0 0 278 289 1 2
XBP1 ASNS 0 0 455 583 1 1
XBP1 NOX4 0 0 265 274 1 2
XBP1 ARF4 0 0 96 182 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0003677 Molecular Function DNA binding enables TAS
GO:0003700 Molecular Function DNA-binding transcription factor activity enables IDA
GO:0000981 Molecular Function DNA-binding transcription factor activity, RNA polymerase II-specific enables IBA
GO:0000978 Molecular Function RNA polymerase II cis-regulatory region sequence-specific DNA binding enables ISS
GO:0000977 Molecular Function RNA polymerase II transcription regulatory region sequence-specific DNA binding enables IBA
GO:0000987 Molecular Function cis-regulatory region sequence-specific DNA binding enables IDA
GO:0042802 Molecular Function identical protein binding enables IPI
GO:0005515 Molecular Function protein binding enables IPI
GO:0046982 Molecular Function protein heterodimerization activity enables IDA
GO:1990837 Molecular Function sequence-specific double-stranded DNA binding enables IDA
GO:0036500 Biological Process ATF6-mediated unfolded protein response involved_in NAS
GO:0036503 Biological Process ERAD pathway involved_in NAS
GO:0036498 Biological Process IRE1-mediated unfolded protein response involved_in TAS
GO:0060612 Biological Process adipose tissue development involved_in ISS
GO:0001525 Biological Process angiogenesis involved_in ISS
GO:0006915 Biological Process apoptotic process involved_in IEA
GO:0006914 Biological Process autophagy involved_in IEA
GO:0071230 Biological Process cellular response to amino acid stimulus involved_in ISS
GO:0071332 Biological Process cellular response to fructose stimulus involved_in ISS
GO:0042149 Biological Process cellular response to glucose starvation involved_in ISS
GO:0071333 Biological Process cellular response to glucose stimulus involved_in ISS
GO:0032869 Biological Process cellular response to insulin stimulus involved_in ISS
GO:0071353 Biological Process cellular response to interleukin-4 involved_in ISS
GO:0071222 Biological Process cellular response to lipopolysaccharide involved_in IDA
GO:0031670 Biological Process cellular response to nutrient involved_in ISS
GO:0071375 Biological Process cellular response to peptide hormone stimulus involved_in ISS
GO:0042632 Biological Process cholesterol homeostasis involved_in ISS
GO:0030968 Biological Process endoplasmic reticulum unfolded protein response involved_in ISS
GO:0006633 Biological Process fatty acid biosynthetic process involved_in TAS
GO:0055089 Biological Process fatty acid homeostasis involved_in ISS
GO:0006955 Biological Process immune response involved_in TAS
GO:0035356 Biological Process intracellular triglyceride homeostasis involved_in ISS
GO:0001889 Biological Process liver development involved_in ISS
GO:0007517 Biological Process muscle organ development involved_in IEA
GO:0043066 Biological Process negative regulation of apoptotic process involved_in ISS
GO:1902236 Biological Process negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway involved_in IDA
GO:0010832 Biological Process negative regulation of myotube differentiation involved_in ISS
GO:0048666 Biological Process neuron development involved_in ISS
GO:0045579 Biological Process positive regulation of B cell differentiation involved_in IDA
GO:0045348 Biological Process positive regulation of MHC class II biosynthetic process involved_in IMP
GO:0045582 Biological Process positive regulation of T cell differentiation involved_in IDA
GO:0045766 Biological Process positive regulation of angiogenesis involved_in IMP
GO:0030335 Biological Process positive regulation of cell migration involved_in IDA
GO:0008284 Biological Process positive regulation of cell population proliferation involved_in IDA
GO:0008284 Biological Process positive regulation of cell population proliferation involved_in IGI
GO:1900103 Biological Process positive regulation of endoplasmic reticulum unfolded protein response involved_in IMP
GO:0045600 Biological Process positive regulation of fat cell differentiation involved_in ISS
GO:2000347 Biological Process positive regulation of hepatocyte proliferation involved_in ISS
GO:0002639 Biological Process positive regulation of immunoglobulin production involved_in IDA
GO:0002639 Biological Process positive regulation of immunoglobulin production involved_in ISS
GO:0032755 Biological Process positive regulation of interleukin-6 production involved_in ISS
GO:1903489 Biological Process positive regulation of lactation involved_in ISS
GO:1900100 Biological Process positive regulation of plasma cell differentiation involved_in IDA
GO:0045944 Biological Process positive regulation of transcription by RNA polymerase II involved_in IDA
GO:0045944 Biological Process positive regulation of transcription by RNA polymerase II involved_in IMP
GO:0045944 Biological Process positive regulation of transcription by RNA polymerase II involved_in ISS
GO:0035470 Biological Process positive regulation of vascular wound healing involved_in IDA
GO:0015031 Biological Process protein transport involved_in IEA
GO:0006357 Biological Process regulation of transcription by RNA polymerase II involved_in NAS
GO:1990418 Biological Process response to insulin-like growth factor stimulus involved_in ISS
GO:0055092 Biological Process sterol homeostasis involved_in ISS
GO:0006366 Biological Process transcription by RNA polymerase II involved_in ISS
GO:0006511 Biological Process ubiquitin-dependent protein catabolic process involved_in ISS
GO:0090575 Cellular Component RNA polymerase II transcription regulator complex part_of IPI
GO:0005737 Cellular Component cytoplasm located_in ISS
GO:0005783 Cellular Component endoplasmic reticulum located_in IDA
GO:0005789 Cellular Component endoplasmic reticulum membrane located_in IEA
GO:0005654 Cellular Component nucleoplasm located_in TAS
GO:0005634 Cellular Component nucleus is_active_in IBA
GO:0005634 Cellular Component nucleus located_in IDA
GO:0005634 Cellular Component nucleus located_in NAS
Pathways
Name DB ID
Cellular responses to stress Reactome R-HSA-2262752
ATF6 (ATF6-alpha) activates chaperones Reactome R-HSA-381033
XBP1(S) activates chaperone genes Reactome R-HSA-381038
IRE1alpha activates chaperones Reactome R-HSA-381070
Unfolded Protein Response (UPR) Reactome R-HSA-381119
ATF6 (ATF6-alpha) activates chaperone genes Reactome R-HSA-381183
Cellular responses to stimuli Reactome R-HSA-8953897
Alzheimer's disease (WP5124) WikiPathways WP5124_r123917
Extrafollicular and follicular B cell activation by SARS-CoV-2 (WP5218) WikiPathways WP5218_r124690
Endoplasmic reticulum stress response in coronavirus infection (WP4861) WikiPathways WP4861_r124658
Alzheimer's disease and miRNA effects (WP2059) WikiPathways WP2059_r119468
Insulin signaling (WP481) WikiPathways WP481_r120562
Unfolded protein response (WP4925) WikiPathways WP4925_r123438
Nonalcoholic fatty liver disease (WP4396) WikiPathways WP4396_r123350
Photodynamic therapy-induced unfolded protein response (WP3613) WikiPathways WP3613_r106539
Transcripts
Accession Version MolecularType Name NCBI Comments
NM_001079539 2 mRNA transcript variant 2 NC_000022 Reference
NM_005080 4 mRNA transcript variant 1 NC_000022 Reference
NM_001393999 1 mRNA transcript variant 3 NC_000022 Reference
NM_001394000 1 mRNA transcript variant 4 NC_000022 Reference