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GAN

gigaxonin
General Information
Name gigaxonin
Alias
  • gigaxonin
  • epididymis secretory sperm binding protein
  • kelch-like family member 16
  • kelch-like protein 16
Gene_family BTB domain containing|Kelch like
organism Homo sapiens
entrez_id 8139
location 16q23.2
transcript_count 2
exon_count 11
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez This gene encodes a member of the cytoskeletal BTB/kelch (Broad-Complex, Tramtrack and Bric a brac) repeat family. The encoded protein plays a role in neurofilament architecture and is involved in mediating the ubiquitination and degradation of some proteins. Defects in this gene are a cause of giant axonal neuropathy (GAN). [provided by RefSeq, Oct 2008]
    Stringdb Gigaxonin; Probable cytoskeletal component that directly or indirectly plays an important role in neurofilament architecture. May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Controls degradation of TBCB. Controls degradation of MAP1B and MAP1S, and is critical for neuronal maintenance and survival; BTB domain containing
    nextProt Probable cytoskeletal component that directly or indirectly plays an important role in neurofilament architecture. May act as a substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Controls degradation of TBCB. Controls degradation of MAP1B and MAP1S, and is critical for neuronal maintenance and survival.
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
GAN BioGRID SFN GeneID BioGRID Affinity Capture-MS
GAN BioGRID ORF6 GeneID BioGRID Affinity Capture-MS
GAN BioGRID ORF1ab GeneID BioGRID Affinity Capture-MS
GAN BioGRID CUL3 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-fractionation
GAN BioGRID CHML GeneID BioGRID Co-fractionation
GAN BioGRID GTPBP3 GeneID BioGRID Co-fractionation
GAN BioGRID CLUH GeneID BioGRID Co-fractionation
GAN BioGRID GLMN GeneID BioGRID Co-fractionation
GAN BioGRID RBX1 GeneID BioGRID Affinity Capture-Western; Co-fractionation
GAN BioGRID YWHAZ GeneID BioGRID Affinity Capture-MS
GAN BioGRID KRT14 GeneID BioGRID Affinity Capture-MS
GAN BioGRID H2AX GeneID BioGRID Affinity Capture-MS
GAN BioGRID GOT1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID GFAP GeneID BioGRID Affinity Capture-MS
GAN BioGRID DES GeneID BioGRID Affinity Capture-MS
GAN BioGRID BAD GeneID BioGRID Affinity Capture-MS
GAN BioGRID NUDCD3 GeneID BioGRID Affinity Capture-MS
GAN BioGRID SAMD4A GeneID BioGRID Affinity Capture-MS
GAN BioGRID UPK1A GeneID BioGRID Affinity Capture-MS
GAN BioGRID ZMYM3 GeneID BioGRID Affinity Capture-MS
GAN BioGRID KRT75 GeneID BioGRID Affinity Capture-MS
GAN BioGRID INA GeneID BioGRID Affinity Capture-MS
GAN BioGRID SLC13A2 GeneID BioGRID Affinity Capture-MS
GAN BioGRID KRT37 GeneID BioGRID Affinity Capture-MS
GAN BioGRID KRT38 GeneID BioGRID Affinity Capture-MS
GAN BioGRID LNP1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID KRT27 GeneID BioGRID Affinity Capture-MS
GAN BioGRID KRT73 GeneID BioGRID Affinity Capture-MS
GAN BioGRID TAF8 GeneID BioGRID Affinity Capture-MS
GAN BioGRID HAUS8 GeneID BioGRID Affinity Capture-MS
GAN BioGRID CTU1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID AJUBA GeneID BioGRID Affinity Capture-MS
GAN BioGRID KBTBD8 GeneID BioGRID Affinity Capture-MS
GAN BioGRID SYNC GeneID BioGRID Affinity Capture-MS
GAN BioGRID VCPIP1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID WDR76 GeneID BioGRID Affinity Capture-MS; Co-purification
GAN BioGRID OR2A4 GeneID BioGRID Affinity Capture-MS
GAN BioGRID MRPS26 GeneID BioGRID Affinity Capture-MS
GAN BioGRID CPEB1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID PAK5 GeneID BioGRID Affinity Capture-MS
GAN BioGRID QRICH1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID INPP5K GeneID BioGRID Affinity Capture-MS
GAN BioGRID ZC3HC1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID TMOD4 GeneID BioGRID Affinity Capture-MS
GAN BioGRID VIM GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
GAN BioGRID S100A4 GeneID BioGRID Affinity Capture-MS
GAN BioGRID RDX GeneID BioGRID Affinity Capture-MS
GAN BioGRID PLOD1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID NEFM GeneID BioGRID Affinity Capture-MS
GAN BioGRID KRT33B GeneID BioGRID Affinity Capture-MS
GAN BioGRID KRT32 GeneID BioGRID Affinity Capture-MS
GAN BioGRID KRT31 GeneID BioGRID Affinity Capture-MS
GAN BioGRID KRT16 GeneID BioGRID Affinity Capture-MS
GAN BioGRID PINK1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID BMH1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID BMH2 GeneID BioGRID Affinity Capture-MS
GAN BioGRID ATG16L1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; PCA
GAN BioGRID VIRMA GeneID BioGRID Affinity Capture-RNA
GAN BioGRID KRT17 GeneID BioGRID Affinity Capture-MS
GAN BioGRID ESR2 GeneID BioGRID Affinity Capture-MS
GAN BioGRID TBCB GeneID BioGRID Affinity Capture-Western; Two-hybrid
GAN BioGRID CBY1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID CSPP1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID ZC3H13 GeneID BioGRID Affinity Capture-MS
GAN BioGRID CUX1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID RPS13 GeneID BioGRID Affinity Capture-MS
GAN BioGRID RPS10 GeneID BioGRID Affinity Capture-MS
GAN BioGRID RPS9 GeneID BioGRID Affinity Capture-MS
GAN BioGRID RPS8 GeneID BioGRID Affinity Capture-MS
GAN BioGRID RPS6 GeneID BioGRID Affinity Capture-MS
GAN BioGRID RPS5 GeneID BioGRID Affinity Capture-MS
GAN BioGRID RPS4X GeneID BioGRID Affinity Capture-MS
GAN BioGRID POTEF GeneID BioGRID Affinity Capture-MS
GAN BioGRID CCDC73 GeneID BioGRID Affinity Capture-MS
GAN BioGRID MYO18A GeneID BioGRID Affinity Capture-MS
GAN BioGRID ANKRD36 GeneID BioGRID Affinity Capture-MS
GAN BioGRID TUBB2B GeneID BioGRID Affinity Capture-MS
GAN BioGRID TUBB8 GeneID BioGRID Affinity Capture-MS
GAN BioGRID ACTBL2 GeneID BioGRID Affinity Capture-MS
GAN BioGRID DCDC1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID TUBB GeneID BioGRID Affinity Capture-MS
GAN BioGRID ZFC3H1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID DNAH10 GeneID BioGRID Affinity Capture-MS
GAN BioGRID SRSF7 GeneID BioGRID Affinity Capture-MS
GAN BioGRID SCN5A GeneID BioGRID Affinity Capture-MS
GAN BioGRID SCN1A GeneID BioGRID Affinity Capture-MS
GAN BioGRID RPS3A GeneID BioGRID Affinity Capture-MS
GAN BioGRID RPS3 GeneID BioGRID Affinity Capture-MS
GAN BioGRID RPS2 GeneID BioGRID Affinity Capture-MS
GAN BioGRID RPLP0 GeneID BioGRID Affinity Capture-MS
GAN BioGRID RPL13 GeneID BioGRID Affinity Capture-MS
GAN BioGRID RPL8 GeneID BioGRID Affinity Capture-MS
GAN BioGRID RPL4 GeneID BioGRID Affinity Capture-MS
GAN BioGRID PRPH GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
GAN BioGRID PRKD1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID PLXNA1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID PLEC GeneID BioGRID Affinity Capture-MS
GAN BioGRID PKD1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID PGM3 GeneID BioGRID Affinity Capture-MS
GAN BioGRID PCNT GeneID BioGRID Affinity Capture-MS
GAN BioGRID PRDX1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID PABPC3 GeneID BioGRID Affinity Capture-MS
GAN BioGRID OXA1L GeneID BioGRID Affinity Capture-MS
GAN BioGRID NPM1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID NEFL GeneID BioGRID Affinity Capture-MS
GAN BioGRID NEFH GeneID BioGRID Affinity Capture-MS
GAN BioGRID NCL GeneID BioGRID Affinity Capture-MS
GAN BioGRID HNRNPM GeneID BioGRID Affinity Capture-MS
GAN BioGRID MUC5AC GeneID BioGRID Affinity Capture-MS
GAN BioGRID MTHFD1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID IRAG2 GeneID BioGRID Affinity Capture-MS
GAN BioGRID RPSA GeneID BioGRID Affinity Capture-MS
GAN BioGRID KRT84 GeneID BioGRID Affinity Capture-MS
GAN BioGRID KRT82 GeneID BioGRID Affinity Capture-MS
GAN BioGRID KRT10 GeneID BioGRID Affinity Capture-MS
GAN BioGRID KRT6B GeneID BioGRID Affinity Capture-MS
GAN BioGRID KRT1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID KIF11 GeneID BioGRID Affinity Capture-MS
GAN BioGRID KIFC3 GeneID BioGRID Affinity Capture-MS
GAN BioGRID HSPD1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID HSP90AB1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID IGSF3 GeneID BioGRID Affinity Capture-MS
GAN BioGRID HSP90AA1 GeneID BioGRID Affinity Capture-Luminescence; Affinity Capture-MS
GAN BioGRID HSPA9 GeneID BioGRID Affinity Capture-MS
GAN BioGRID HSPA8 GeneID BioGRID Affinity Capture-MS
GAN BioGRID HSPA6 GeneID BioGRID Affinity Capture-MS
GAN BioGRID HSPA2 GeneID BioGRID Affinity Capture-MS
GAN BioGRID HSPA1L GeneID BioGRID Affinity Capture-MS
GAN BioGRID HSPA1A GeneID BioGRID Affinity Capture-MS
GAN BioGRID PRMT1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID HNRNPU GeneID BioGRID Affinity Capture-MS
GAN BioGRID HNRNPH1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID HNRNPF GeneID BioGRID Affinity Capture-MS
GAN BioGRID HNRNPC GeneID BioGRID Affinity Capture-MS
GAN BioGRID HNRNPA1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID EIF4B GeneID BioGRID Affinity Capture-MS
GAN BioGRID EIF4A1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID CELSR3 GeneID BioGRID Affinity Capture-MS
GAN BioGRID EEF2 GeneID BioGRID Affinity Capture-MS
GAN BioGRID DNAH8 GeneID BioGRID Affinity Capture-MS
GAN BioGRID DNAH6 GeneID BioGRID Affinity Capture-MS
GAN BioGRID DMD GeneID BioGRID Affinity Capture-MS
GAN BioGRID PRPF31 GeneID BioGRID Affinity Capture-MS
GAN BioGRID CLASP1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID NUP160 GeneID BioGRID Affinity Capture-MS
GAN BioGRID PLCB1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID SYNE2 GeneID BioGRID Affinity Capture-MS
GAN BioGRID PHLDB1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID ZZEF1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID MAST2 GeneID BioGRID Affinity Capture-MS
GAN BioGRID KIF21B GeneID BioGRID Affinity Capture-MS
GAN BioGRID NINL GeneID BioGRID Affinity Capture-MS
GAN BioGRID CCT5 GeneID BioGRID Affinity Capture-MS
GAN BioGRID STK38 GeneID BioGRID Affinity Capture-MS
GAN BioGRID SPIN1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID CCT8 GeneID BioGRID Affinity Capture-MS
GAN BioGRID CCT6B GeneID BioGRID Affinity Capture-MS
GAN BioGRID CCT2 GeneID BioGRID Affinity Capture-MS
GAN BioGRID CCT4 GeneID BioGRID Affinity Capture-MS
GAN BioGRID CCT7 GeneID BioGRID Affinity Capture-MS
GAN BioGRID PRMT5 GeneID BioGRID Affinity Capture-MS
GAN BioGRID RACK1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID TUBB4B GeneID BioGRID Affinity Capture-MS
GAN BioGRID TUBB4A GeneID BioGRID Affinity Capture-MS
GAN BioGRID TUBB3 GeneID BioGRID Affinity Capture-MS
GAN BioGRID TUBA1B GeneID BioGRID Affinity Capture-MS
GAN BioGRID CEBPZ GeneID BioGRID Affinity Capture-MS
GAN BioGRID TRAP1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID THRAP3 GeneID BioGRID Affinity Capture-MS
GAN BioGRID HELZ GeneID BioGRID Affinity Capture-MS
GAN BioGRID BCLAF1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID CROCC GeneID BioGRID Affinity Capture-MS
GAN BioGRID DLG5 GeneID BioGRID Affinity Capture-MS
GAN BioGRID ARHGEF1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID CACNA1H GeneID BioGRID Affinity Capture-MS
GAN BioGRID PABPC4 GeneID BioGRID Affinity Capture-MS
GAN BioGRID EIF3I GeneID BioGRID Affinity Capture-MS
GAN BioGRID EIF3D GeneID BioGRID Affinity Capture-MS
GAN BioGRID EIF3C GeneID BioGRID Affinity Capture-MS
GAN BioGRID EIF3B GeneID BioGRID Affinity Capture-MS
GAN BioGRID EIF3A GeneID BioGRID Affinity Capture-MS
GAN BioGRID MAP4K3 GeneID BioGRID Affinity Capture-MS
GAN BioGRID TRRAP GeneID BioGRID Affinity Capture-MS
GAN BioGRID EPX GeneID BioGRID Affinity Capture-MS
GAN BioGRID RBM10 GeneID BioGRID Affinity Capture-MS
GAN BioGRID TUBA1A GeneID BioGRID Affinity Capture-MS
GAN BioGRID ALMS1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID WIPF1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID TTN GeneID BioGRID Affinity Capture-MS
GAN BioGRID CCT3 GeneID BioGRID Affinity Capture-MS
GAN BioGRID TCP1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID TRIM21 GeneID BioGRID Affinity Capture-MS
GAN BioGRID SPTB GeneID BioGRID Affinity Capture-MS
GAN BioGRID SPTAN1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID SPTA1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID SNRPN GeneID BioGRID Affinity Capture-MS
GAN BioGRID RPS27A GeneID BioGRID Affinity Capture-MS
GAN BioGRID EEF1A1P5 GeneID BioGRID Affinity Capture-MS
GAN BioGRID DNHD1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID SPINDOC GeneID BioGRID Affinity Capture-MS
GAN BioGRID ZNF618 GeneID BioGRID Affinity Capture-MS
GAN BioGRID ZNF616 GeneID BioGRID Affinity Capture-MS
GAN BioGRID SSH2 GeneID BioGRID Affinity Capture-MS
GAN BioGRID LMNB2 GeneID BioGRID Affinity Capture-MS
GAN BioGRID HYCC1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID ZNF469 GeneID BioGRID Affinity Capture-MS
GAN BioGRID TUBB6 GeneID BioGRID Affinity Capture-MS
GAN BioGRID RIOK1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID TEKT1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID GPR101 GeneID BioGRID Affinity Capture-MS
GAN BioGRID MYH14 GeneID BioGRID Affinity Capture-MS
GAN BioGRID DYNC2H1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID WDR77 GeneID BioGRID Affinity Capture-MS
GAN BioGRID EEFSEC GeneID BioGRID Affinity Capture-MS
GAN BioGRID ANKRD36B GeneID BioGRID Affinity Capture-MS
GAN BioGRID RNF213 GeneID BioGRID Affinity Capture-MS
GAN BioGRID CIP2A GeneID BioGRID Affinity Capture-MS
GAN BioGRID CFAP44 GeneID BioGRID Affinity Capture-MS
GAN BioGRID CEP72 GeneID BioGRID Affinity Capture-MS
GAN BioGRID TENM3 GeneID BioGRID Affinity Capture-MS
GAN BioGRID CARMIL1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID ATAD3A GeneID BioGRID Affinity Capture-MS
GAN BioGRID PARP14 GeneID BioGRID Affinity Capture-MS
GAN BioGRID KCTD5 GeneID BioGRID Affinity Capture-MS
GAN BioGRID SEMA5B GeneID BioGRID Affinity Capture-MS
GAN BioGRID DNAJC10 GeneID BioGRID Affinity Capture-MS
GAN BioGRID MRPL39 GeneID BioGRID Affinity Capture-MS
GAN BioGRID TUBA8 GeneID BioGRID Affinity Capture-MS
GAN BioGRID EIF3L GeneID BioGRID Affinity Capture-MS
GAN BioGRID SPTBN5 GeneID BioGRID Affinity Capture-MS
GAN BioGRID SETD2 GeneID BioGRID Affinity Capture-MS
GAN BioGRID PABPC1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID CTNNA2 GeneID BioGRID Affinity Capture-MS
GAN BioGRID COL6A3 GeneID BioGRID Affinity Capture-MS
GAN BioGRID CCT6A GeneID BioGRID Affinity Capture-MS
GAN BioGRID ZNHIT2 GeneID BioGRID Affinity Capture-MS
GAN BioGRID DST GeneID BioGRID Affinity Capture-MS
GAN BioGRID APBB2 GeneID BioGRID Affinity Capture-MS
GAN BioGRID SLC25A6 GeneID BioGRID Affinity Capture-MS
GAN BioGRID SLC25A5 GeneID BioGRID Affinity Capture-MS
GAN BioGRID SLC25A4 GeneID BioGRID Affinity Capture-MS
GAN BioGRID ACTG1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID RTTN GeneID BioGRID Affinity Capture-MS
GAN BioGRID MXRA5 GeneID BioGRID Affinity Capture-MS
GAN BioGRID ARHGEF12 GeneID BioGRID Affinity Capture-MS
GAN BioGRID SYNE1 GeneID BioGRID Affinity Capture-MS
GAN BioGRID GAN GeneID BioGRID Biochemical Activity
GAN BioGRID RELA GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
GAN BioGRID UBA1 GeneID BioGRID Affinity Capture-Western; Two-hybrid
GAN Protein TBCB GeneID HPRD
GAN Protein UBA1 GeneID HPRD
GAN Protein MAP1B GeneID HPRD
GAN BioGRID MAP1B GeneID BioGRID Affinity Capture-Western
StringDB
A B experiments database textmining combined score hadb nhadb
GAN SBF2 0 0 325 339 1 1
GAN RAB7B 0 0 151 150 1 1
GAN RBX1 270 900 274 944 1 1
GAN TRRAP 270 0 0 317 1 1
GAN ZC3H13 410 0 0 414 1 1
GAN GIPC2 0 0 0 221 1 1
GAN UBA3 0 0 0 173 1 1
GAN PIAS4 0 0 0 171 1 1
GAN COMMD3 0 600 0 600 1 1
GAN SKP1 0 0 204 218 1 2
GAN PRMT5 270 0 0 280 1 1
GAN LCOR 0 0 140 163 1 1
GAN PKD1 270 0 0 270 1 1
GAN BIRC6 0 0 0 191 1 1
GAN TUBB8 270 0 0 285 1 1
GAN KLHL2 0 720 508 823 1 1
GAN RNF112 0 0 96 152 1 1
GAN SLC25A5 270 0 0 270 1 1
GAN SRSF7 270 0 0 282 1 1
GAN NAGLU 0 0 151 452 1 1
GAN FAM126A 270 0 74 325 1 1
GAN DNAH6 270 0 0 270 1 1
GAN STK25 0 0 134 152 1 1
GAN UBE2C 0 0 0 153 1 1
GAN KLHL7 0 900 519 917 1 1
GAN KLHL13 0 900 372 912 1 1
GAN COMMD10 0 600 0 607 1 1
GAN IGHMBP2 0 0 184 365 1 1
GAN POLB 0 0 217 227 1 1
GAN SPTAN1 270 0 0 282 1 1
GAN CCT3 270 0 0 270 1 1
GAN ENSG00000250232 0 0 0 193 1 1
GAN RTTN 270 0 0 270 1 1
GAN KLHDC7A 0 0 108 187 1 1
GAN SENP2 0 0 95 193 1 1
GAN TIMM44 0 0 0 161 1 1
GAN SMURF2 0 0 74 197 1 1
GAN RPS8 270 0 0 270 1 1
GAN KLHL17 0 0 509 198 1 1
GAN ARHGEF12 270 0 0 343 1 1
GAN SPG21 0 0 181 379 1 1
GAN UBE2E2 0 0 0 156 1 1
GAN TRIM2 0 0 235 403 1 1
GAN FBXO2 0 0 97 153 1 1
GAN RNF213 270 0 0 285 1 1
GAN DNAL1 0 0 764 774 1 1
GAN SPTA1 270 0 0 282 1 1
GAN DCDC1 270 0 0 270 1 1
GAN SLC12A6 0 0 325 338 1 1
GAN PABPC4 270 0 0 276 1 1
GAN PRX 0 0 329 329 1 1
GAN HSP90AB1 394 0 87 431 1 2
GAN GAS2 0 0 82 235 1 1
GAN ING5 0 0 123 218 1 1
GAN BSCL2 0 0 141 153 1 1
GAN RNF7 0 0 175 187 1 1
GAN DHX16 0 0 53 163 1 1
GAN ZNHIT2 270 0 0 270 1 1
GAN THRAP3 270 0 0 270 1 1
GAN EIF3L 270 0 0 270 1 1
GAN SCN5A 270 0 0 281 1 1
GAN ENSG00000279392 0 0 55 157 1 1
GAN SSH2 270 0 0 283 1 1
GAN RNF216 0 0 181 416 1 1
GAN CELSR3 270 0 0 270 1 1
GAN KATNA1 0 0 193 293 1 1
GAN SPTB 270 0 0 299 1 1
GAN GIPC1 0 0 0 323 1 1
GAN UBE3A 0 0 166 194 1 1
GAN SETX 0 0 249 259 1 1
GAN GLYAT 0 0 0 175 1 1
GAN RBAK 0 0 90 163 1 1
GAN SYNE2 270 0 0 282 1 1
GAN ALS2 0 0 66 243 1 1
GAN ZDHHC19 0 0 263 279 1 1
GAN GARS 0 0 264 264 1 1
GAN ANKRD36 270 0 0 303 1 1
GAN WIPI2 0 0 172 213 1 2
GAN FMR1 0 0 398 398 1 1
GAN IGBP1 0 0 0 169 1 1
GAN RPLP0 270 0 0 280 1 1
GAN ZFYVE26 0 0 189 189 1 1
GAN ABCA6 0 0 161 186 1 1
GAN EEF2 270 0 0 270 1 2
GAN PLCB1 270 0 0 270 1 1
GAN TUBB4B 270 0 0 281 1 1
GAN PMP22 0 0 246 293 1 1
GAN HSPA2 270 0 0 270 1 1
GAN TRAP1 270 0 0 270 1 2
GAN PIAS2 0 0 0 171 1 1
GAN CCT2 270 0 0 270 1 1
GAN RPS10 270 0 0 270 1 1
GAN ENSG00000132716 0 0 465 476 1 1
GAN ROR2 0 0 137 333 1 1
GAN UBE2Z 0 0 0 153 1 1
GAN WDR45 0 0 138 274 1 2
GAN SYNE1 270 0 0 282 1 1
GAN CUL4B 0 0 193 313 1 1
GAN TCP1 270 0 0 270 1 1
GAN NFE2L3 0 0 0 166 1 1
GAN RAB7A 0 0 181 268 1 2
GAN OXA1L 270 0 0 270 1 1
GAN GINS4 0 0 276 314 1 1
GAN KIFC3 270 0 0 270 1 1
GAN MYO18A 270 0 0 281 1 1
GAN SPTBN5 270 0 0 303 1 1
GAN WDR77 270 0 0 289 1 1
GAN DVL2 0 0 0 152 1 2
GAN DCUN1D4 0 600 0 604 1 1
GAN HNRNPA3 0 0 44 542 1 1
GAN KLHL25 0 900 391 911 1 1
GAN COMMD7 0 600 0 606 1 1
GAN RPS9 270 0 0 270 1 1
GAN GINS3 0 0 294 343 1 1
GAN HSPA9 270 0 0 280 1 1
GAN EGR2 0 0 194 209 1 1
GAN ACTR10 0 0 194 452 1 1
GAN CLASP1 270 0 0 270 1 1
GAN CFAP44 270 0 0 287 1 1
GAN CCT6A 270 0 0 270 1 1
GAN MXRA5 270 0 0 270 1 1
GAN MAP4K3 270 0 0 271 1 1
GAN MYCBP2 0 0 203 256 1 1
GAN ALMS1 270 0 0 270 1 1
GAN COL6A3 270 0 0 270 1 1
GAN GNB2L1 270 0 0 270 1 1
GAN TUBA1A 270 0 0 290 1 1
GAN CROCC 270 0 0 270 1 1
GAN HELZ 270 0 0 270 1 1
GAN KCTD10 0 720 73 729 1 1
GAN DNAJB2 0 0 150 168 1 1
GAN BTBD19 0 0 0 153 1 1
GAN SYNM 0 0 253 644 1 1
GAN BRS3 0 0 46 643 1 1
GAN WIPF1 270 0 0 270 1 1
GAN SMN2 0 0 181 268 1 1
GAN AARS 0 0 0 154 1 1
GAN SEMA5B 270 0 0 270 1 1
GAN GBA2 0 0 207 349 1 1
GAN NFE2L1 0 0 0 166 1 1
GAN PLXNC1 0 0 0 207 1 1
GAN MKLN1 0 0 113 172 1 1
GAN KLHL22 0 900 85 901 1 1
GAN LMNB2 270 0 123 332 1 1
GAN DOCK4 0 0 0 190 1 1
GAN KLHL40 0 720 454 765 1 1
GAN TNFAIP1 0 900 175 913 1 1
GAN EIF3C 270 0 0 273 1 1
GAN ACTG1 270 0 0 288 1 1
GAN DLG4 0 0 49 337 1 2
GAN DMD 270 0 389 542 1 2
GAN RPS3A 270 0 0 270 1 1
GAN NPM1 270 0 0 270 1 1
GAN UBE2S 0 0 82 215 1 1
GAN ZNF616 270 0 0 284 1 1
GAN GFAP 0 0 413 425 1 2
GAN ZNF469 270 0 0 284 1 1
GAN KLHL3 0 900 602 946 1 1
GAN RPS13 270 0 0 270 1 1
GAN EIF3D 270 0 0 270 1 1
GAN COMMD6 0 600 0 600 1 1
GAN LITAF 0 0 242 241 1 1
GAN NUDCD3 198 0 0 270 1 1
GAN TENM3 270 0 0 270 1 1
GAN SETD2 270 0 0 297 1 1
GAN DCUN1D2 0 600 0 604 1 1
GAN DST 270 0 107 427 1 2
GAN KCTD13 0 900 156 911 1 1
GAN KLHL42 0 900 390 924 1 1
GAN CTNNA2 270 0 0 270 1 1
GAN HNRNPDL 0 0 0 303 1 1
GAN KRT82 270 0 94 343 1 1
GAN EPX 270 0 0 270 1 1
GAN NEB 0 0 94 177 1 1
GAN HSPB1 0 0 95 158 1 2
GAN KLHL23 0 0 285 228 1 1
GAN CDC45 0 0 248 248 1 1
GAN PHLDB1 270 0 0 270 1 1
GAN NETO1 0 0 53 247 1 1
GAN PIAS3 0 0 0 171 1 1
GAN MRPL39 270 0 0 270 1 1
GAN PRKD1 270 0 0 270 1 1
GAN CACUL1 0 0 0 183 1 1
GAN ATG5 0 0 96 205 1 2
GAN MIB1 0 0 0 157 1 1
GAN COMMD4 0 600 0 600 1 1
GAN GIT1 0 0 0 157 1 1
GAN NUP160 270 0 0 278 1 1
GAN RBM10 270 0 0 272 1 1
GAN NCL 270 0 72 372 1 2
GAN UBE2D2 0 0 53 167 1 1
GAN TUBB 270 0 0 281 1 1
GAN ACTBL2 270 0 0 288 1 1
GAN POLD1 0 0 445 445 1 1
GAN UBQLN2 0 0 126 595 1 2
GAN LZTR1 0 900 373 935 1 1
GAN ATXN3 0 0 194 246 1 2
GAN CCDC22 0 600 0 602 1 1
GAN PLXNA4 0 0 0 179 1 1
GAN PEX3 0 0 123 369 1 2
GAN DNAJC10 270 0 0 285 1 1
GAN PIAS1 0 0 0 171 1 1
GAN GIT2 0 0 0 157 1 1
GAN FAM213B 0 0 75 154 1 1
GAN ZMYND11 0 0 141 289 1 1
GAN UBE2E3 0 0 0 156 1 1
GAN EEFSEC 270 0 0 285 1 1
GAN SFXN5 0 0 97 173 1 1
GAN RHOBTB3 0 0 193 218 1 1
GAN CCT6B 270 0 0 270 1 1
GAN SGK223 0 0 64 160 1 1
GAN SNX16 0 0 216 351 1 1
GAN AGPAT6 0 0 127 187 1 1
GAN TCEB1 0 0 170 257 1 1
GAN EIF3B 270 0 0 277 1 1
GAN CEP44 0 0 108 169 1 1
GAN PRKAR1A 0 0 0 208 1 2
GAN CCT7 270 0 0 270 1 1
GAN SPIN1 270 0 0 270 1 1
GAN RND2 0 0 0 221 1 1
GAN HNRNPC 270 0 0 270 1 1
GAN UEVLD 0 0 95 184 1 1
GAN ARHGEF1 270 0 0 275 1 1
GAN ZZEF1 270 0 0 270 1 1
GAN CACNA1H 270 0 0 281 1 1
GAN CUL3 486 900 716 986 1 2
GAN NINL 270 0 0 270 1 1
GAN SAMHD1 0 0 0 187 1 1
GAN APBB2 270 0 0 270 1 1
GAN EIF3A 270 0 0 281 1 1
GAN RPS4X 270 0 0 270 1 1
GAN RPS27A 270 0 0 281 1 1
GAN SFN 274 0 0 327 1 2
GAN ASUN 0 0 90 152 1 1
GAN TUBA8 270 0 0 290 1 1
GAN NRM 0 0 242 443 1 1
GAN ATG16L1 462 0 143 519 1 2
GAN PGM3 270 0 0 270 1 1
GAN DNAJA2 0 0 0 154 1 1
GAN SLC45A3 0 0 0 206 1 1
GAN RPSA 270 0 0 270 1 1
GAN TUBB2B 270 0 0 281 1 1
GAN KLHL11 0 0 635 323 1 1
GAN KRT6B 270 0 0 285 1 1
GAN TUBB6 270 0 0 281 1 1
GAN CCDC73 270 0 0 270 1 1
GAN EIF4B 270 0 0 270 1 1
GAN CEBPZ 270 0 0 270 1 1
GAN HSPB8 0 0 235 235 1 2
GAN KIAA1524 270 0 0 270 1 1
GAN DPEP1 0 0 138 295 1 1
GAN KLHL20 0 900 455 919 1 1
GAN SACS 0 0 144 178 1 1
GAN TGM6 0 0 53 155 1 1
GAN DCDC2 0 0 134 166 1 1
GAN GPR101 270 0 0 270 1 1
GAN RHOBTB1 0 0 0 157 1 1
GAN KCTD5 270 540 88 681 1 1
GAN IBTK 0 0 167 167 1 1
GAN MFN2 0 0 294 310 1 2
GAN DNAH10 270 0 0 270 1 1
GAN SCN1A 270 0 0 281 1 1
GAN LMTK2 0 0 184 183 1 1
GAN KLHL9 0 900 608 918 1 1
GAN EIF3I 270 0 0 270 1 1
GAN BFSP1 0 0 166 165 1 1
GAN ASPA 0 0 42 188 1 1
GAN PAX2 0 0 105 174 1 1
GAN KIAA1429 270 0 0 270 1 1
GAN NDRG1 0 0 194 194 1 1
GAN CCT5 270 0 0 270 1 1
GAN RPS6 270 0 0 270 1 2
GAN KLHL31 0 0 466 175 1 1
GAN MPZ 0 0 420 420 1 1
GAN BICC1 0 0 0 168 1 1
GAN SMN1 0 0 181 268 1 1
GAN PIK3C3 0 0 0 172 1 2
GAN POTEF 270 0 0 288 1 1
GAN GJB3 0 0 107 206 1 1
GAN MYO5A 0 0 139 205 1 1
GAN L1CAM 0 0 0 181 1 1
GAN PRMT1 270 0 0 270 1 1
GAN RRAS 0 0 50 209 1 1
GAN PLEC 270 0 266 541 1 1
GAN CUL7 0 0 215 215 1 1
GAN GRIK2 0 0 122 215 1 1
GAN ZFC3H1 270 0 0 270 1 1
GAN RPS3 270 0 0 275 1 1
GAN SLC25A6 270 0 0 270 1 1
GAN HSPD1 270 0 0 270 1 1
GAN KLHL15 0 360 0 360 1 1
GAN AGGF1 0 0 61 163 1 1
GAN COMMD9 0 600 0 600 1 1
GAN ZFP2 0 0 95 150 1 1
GAN DCUN1D5 0 600 0 604 1 1
GAN HSPA1L 270 0 0 270 1 1
GAN RHOBTB2 0 0 123 325 1 1
GAN LRSAM1 0 0 213 428 1 2
GAN NFE2 0 0 48 172 1 1
GAN UGT2A3 0 0 173 173 1 1
GAN UBE2D3 0 0 0 156 1 1
GAN NEFM 682 0 335 793 1 1
GAN GABARAPL2 0 0 51 225 1 2
GAN BFSP2 0 0 150 181 1 1
GAN KLHL24 0 720 233 742 1 1
GAN CDK10 0 0 139 150 1 1
GAN PABPC3 270 0 0 276 1 1
GAN APTX 0 0 261 261 1 1
GAN RELA 270 0 0 274 1 2
GAN TUBB4A 270 0 54 291 1 1
GAN RPL13 270 0 0 270 1 1
GAN GJB1 0 0 359 359 1 1
GAN CCDC171 0 0 103 239 1 1
GAN KLHL21 0 900 143 903 1 1
GAN RIOK1 270 0 0 285 1 1
GAN ARHGEF28 0 0 183 188 1 1
GAN DVL1 0 0 0 152 1 1
GAN KIF21B 270 0 0 285 1 1
GAN UBE2D1 0 0 0 156 1 1
GAN BTBD9 0 0 0 154 1 1
GAN FA2H 0 0 124 291 1 1
GAN DIRC2 0 0 134 512 1 1
GAN PARK2 94 0 113 194 1 1
GAN WNK4 0 0 107 355 1 1
GAN PCNT 270 0 0 270 1 1
GAN DNHD1 270 0 0 270 1 1
GAN BACH1 0 0 0 194 1 1
GAN PLXNA2 0 0 0 179 1 1
GAN BSPH1 0 0 120 175 1 1
GAN GRPR 0 0 0 303 1 1
GAN HNRNPU 270 0 0 270 1 1
GAN MTMR2 0 0 370 383 1 1
GAN UBE2K 0 0 0 169 1 1
GAN BACH2 0 0 0 166 1 1
GAN NFE2L2 0 0 58 181 1 2
GAN GDAP1 0 0 502 502 1 1
GAN TBCB 486 0 649 876 1 1
GAN UBA1 270 0 868 903 1 1
GAN SYNC 214 0 73 240 1 1
GAN TTN 270 0 0 354 1 1
GAN FLNA 0 0 74 266 1 1
GAN C9orf72 0 0 120 274 1 2
GAN MAP1A 0 0 0 262 1 2
GAN DNAH8 270 0 0 270 1 1
GAN PABPC1 270 0 0 276 1 1
GAN SLC25A4 270 0 0 270 1 1
GAN ADAM33 0 0 0 190 1 1
GAN SUMF1 0 0 57 240 1 1
GAN KRT10 270 0 0 270 1 1
GAN CSPP1 283 0 0 282 1 1
GAN KLHDC2 0 0 71 230 1 1
GAN HNRNPA1L2 0 0 0 206 1 1
GAN CUL2 0 0 166 386 1 1
GAN PRPH 270 0 0 285 1 1
GAN KLHL8 0 900 113 902 1 1
GAN PEF1 0 720 46 726 1 1
GAN LMNA 0 0 255 254 1 2
GAN NEDD8 0 600 242 691 1 2
GAN KRT84 270 0 0 297 1 1
GAN DCUN1D1 0 600 0 616 1 1
GAN COMMD8 0 600 0 608 1 1
GAN EPS15 0 0 97 163 1 1
GAN DHH 0 0 194 194 1 1
GAN MYH14 270 0 0 281 1 1
GAN BTBD6 0 0 323 219 1 1
GAN UBE2T 0 0 0 156 1 1
GAN ZNF618 270 0 0 284 1 1
GAN WDR42A 0 0 465 476 1 1
GAN MUC5AC 270 0 0 270 1 1
GAN RMND5A 0 0 124 164 1 1
GAN SPTLC1 0 0 143 152 1 1
GAN PRPF31 270 0 0 285 1 1
GAN ENC1 0 900 419 914 1 1
GAN PDCD6 0 720 0 726 1 1
GAN PAK1 0 0 97 190 1 2
GAN KARS 0 0 64 151 1 1
GAN WNT5B 0 0 57 152 1 1
GAN TUBB3 270 0 0 281 1 1
GAN ZMIZ1 0 0 0 171 1 1
GAN SNCAIP 0 0 0 154 1 2
GAN SPOPL 0 900 91 916 1 1
GAN CUL1 0 0 236 349 1 1
GAN KCTD17 0 900 160 912 1 1
GAN COMMD1 0 600 0 600 1 1
GAN ZMIZ2 0 0 0 171 1 1
GAN EIF4A1 270 0 0 270 1 1
GAN CUL5 0 0 207 325 1 1
GAN NMNAT2 0 0 90 175 1 1
GAN POLG 0 0 82 183 1 1
GAN MAP1B 270 0 903 951 1 2
GAN CUX1 270 0 0 288 1 1
GAN KLHL6 0 0 213 239 1 1
GAN NMBR 0 0 0 209 1 1
GAN KLHL1 0 0 335 206 1 1
GAN TBCE 0 0 372 372 1 1
GAN GLMN 0 720 57 724 1 1
GAN TRIM21 270 0 0 270 1 1
GAN MACF1 0 0 184 282 1 1
GAN NEFL 270 0 556 684 1 1
GAN AKTIP 0 0 0 225 1 1
GAN UBE2D4 0 0 0 156 1 1
GAN PRKAR1B 0 0 142 331 1 1
GAN SKP2 0 0 165 200 1 2
GAN VIM 736 0 647 902 1 2
GAN KCTD2 0 540 142 593 1 1
GAN DYNC2H1 270 0 0 270 1 1
GAN ZSCAN23 0 0 125 213 1 1
GAN MAP1S 0 0 610 654 1 2
GAN HNRNPA2B1 0 0 0 206 1 1
GAN HSPA6 270 0 0 270 1 1
GAN RPS5 270 0 0 270 1 1
GAN CLDN11 0 0 85 334 1 1
GAN LRMP 270 0 0 279 1 1
GAN TDP1 0 0 323 352 1 1
GAN DLG5 270 0 0 298 1 1
GAN KCTD6 0 0 230 229 1 1
GAN KLHL41 0 900 420 914 1 1
GAN IGSF3 270 0 0 270 1 1
GAN C12orf65 0 0 179 179 1 1
GAN SNRPN 270 0 0 270 1 1
GAN GAK 0 0 112 153 1 1
GAN KBTBD8 130 900 378 923 1 1
GAN IMMT 0 0 0 207 1 1
GAN HSPA1A 270 0 0 270 1 1
GAN KIF1B 0 0 322 321 1 1
GAN GPKOW 0 0 0 157 1 1
GAN SGSH 0 0 155 154 1 1
GAN INA 682 0 507 893 1 1
GAN GIPC3 0 0 0 163 1 1
GAN NEIL2 0 0 176 190 1 1
GAN KCTD21 0 0 259 258 1 1
GAN DVL3 0 0 0 152 1 1
GAN C10orf12 0 0 143 291 1 1
GAN CCT8 270 0 0 270 1 1
GAN TPP1 0 0 49 208 1 1
GAN POLD4 0 0 294 294 1 1
GAN KIF11 270 0 0 285 1 1
GAN HNRNPA1 270 0 0 395 1 1
GAN CBFA2T2 0 0 60 158 1 1
GAN ATAD3A 270 0 0 270 1 1
GAN OTUD4 0 0 155 322 1 1
GAN KRT1 270 0 0 287 1 1
GAN PRDX1 270 0 0 284 1 1
GAN EIF3M 0 0 162 161 1 1
GAN SOD1 0 0 132 222 1 2
GAN MIB2 0 0 0 157 1 1
GAN PARP14 270 0 0 276 1 1
GAN SMC3 0 0 0 155 1 1
GAN TEKT1 270 0 0 270 1 1
GAN SPOP 0 900 325 923 1 1
GAN RPL4 270 0 0 270 1 1
GAN ANKRD36B 270 0 0 285 1 1
GAN MCM3AP 0 0 156 155 1 1
GAN LRRC16A 270 0 0 270 1 1
GAN MAST2 270 0 0 300 1 1
GAN POLR3D 0 0 164 347 1 1
GAN COMMD5 0 600 0 602 1 1
GAN TRIM3 0 0 0 252 1 1
GAN ARSA 0 0 103 198 1 2
GAN HNRNPM 270 0 0 270 1 1
GAN UBE2N 0 0 0 156 1 1
GAN PLXNA1 270 0 63 567 1 1
GAN KLHDC10 0 0 81 251 1 1
GAN C11orf84 270 0 0 270 1 1
GAN HNRNPH1 270 0 0 270 1 1
GAN BCLAF1 270 0 0 270 1 1
GAN HSPA8 270 0 0 270 1 2
GAN UBE2L3 0 0 55 157 1 1
GAN PLXNA3 0 0 0 237 1 1
GAN ABTB1 0 0 243 370 1 1
GAN CTTNBP2NL 0 0 223 223 1 1
GAN CCT4 270 0 0 270 1 1
GAN TUBA1B 270 0 0 290 1 1
GAN RPL8 270 0 0 270 1 1
GAN FEN1 0 0 139 189 1 1
GAN CYP2U1 0 0 151 302 1 1
GAN COMMD2 0 600 0 600 1 1
GAN KBTBD13 0 0 298 215 1 1
GAN SH3TC2 0 0 364 364 1 1
GAN CEP72 270 0 0 281 1 1
GAN HSP90AA1 394 0 96 441 1 2
GAN SLC51B 0 0 123 177 1 1
GAN KLHDC1 0 0 108 278 1 1
GAN STK38 270 0 0 285 1 1
GAN KEAP1 0 900 341 910 1 2
GAN MTHFD1 270 0 0 282 1 1
GAN CUL4A 0 0 157 282 1 1
GAN UBE2E1 0 0 0 156 1 1
GAN HNRNPF 270 0 0 270 1 1
GAN CUL9 0 0 112 154 1 1
GAN KBTBD4 0 0 458 209 1 1
GAN KLHL12 0 900 470 912 1 1
GAN NEFH 270 0 427 573 1 1
GAN RPS2 270 0 0 285 1 1
GAN SPG7 0 0 204 304 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0003674 Molecular Function molecular_function enables ND
GO:0005515 Molecular Function protein binding enables IPI
GO:0007010 Biological Process cytoskeleton organization involved_in IEA
GO:0016567 Biological Process protein ubiquitination involved_in IDA
GO:0016567 Biological Process protein ubiquitination involved_in IEA
GO:0031463 Cellular Component Cul3-RING ubiquitin ligase complex part_of IDA
GO:0005737 Cellular Component cytoplasm located_in IDA
GO:0005856 Cellular Component cytoskeleton located_in IEA
GO:0005829 Cellular Component cytosol located_in TAS
Pathways
Name DB ID
Adaptive Immune System Reactome R-HSA-1280218
Immune System Reactome R-HSA-168256
Metabolism of proteins Reactome R-HSA-392499
Post-translational protein modification Reactome R-HSA-597592
Neddylation Reactome R-HSA-8951664
Antigen processing: Ubiquitination & Proteasome degradation Reactome R-HSA-983168
Class I MHC mediated antigen processing & presentation Reactome R-HSA-983169
Transcripts
Accession Version MolecularType Name NCBI Comments
NM_022041 4 mRNA transcript variant 1 NC_000016 Reference
NM_001377486 1 mRNA transcript variant 2 NC_000016 Reference