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CAMP

cathelicidin antimicrobial peptide
General Information
Name cathelicidin antimicrobial peptide
Alias
  • cathelicidin antimicrobial peptide
  • 18 kDa cationic antimicrobial protein
  • epididymis secretory sperm binding protein
Gene_family Receptor ligands
organism Homo sapiens
entrez_id 820
location 3p21.31
transcript_count 1
exon_count 4
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez This gene encodes a member of an antimicrobial peptide family, characterized by a highly conserved N-terminal signal peptide containing a cathelin domain and a structurally variable cationic antimicrobial peptide, which is produced by extracellular proteolysis from the C-terminus. The protein plays an important role in innate immunity defense against viruses. In addition to its antibacterial, antifungal, and antiviral activities, the encoded protein functions in cell chemotaxis, immune mediator induction, and inflammatory response regulation. [provided by RefSeq, Sep 2021]
    Stringdb Cathelicidin antimicrobial peptide; Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity; Endogenous ligands
    nextProt Antimicrobial protein that is an integral component of the innate immune system (PubMed:22879591, PubMed:16637646, PubMed:18818205, PubMed:9736536, PubMed:14978112). Binds to bacterial lipopolysaccharides (LPS) (PubMed:16637646, PubMed:18818205). Acts via neutrophil N-formyl peptide receptors to enhance the release of CXCL2 (PubMed:22879591). Postsecretory processing generates multiple cathelicidin antimicrobial peptides with various lengths which act as a topical antimicrobial defense in sweat on skin (PubMed:14978112). The unprocessed precursor form, cathelicidin antimicrobial peptide, inhibits the growth of Gram-negative E.coli and E.aerogenes with efficiencies comparable to that of the mature peptide LL-37 (in vitro) (PubMed:9736536).
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
CAMP BioGRID S GeneID BioGRID Protein-peptide
CAMP BioGRID ACE2 GeneID BioGRID Protein-peptide
CAMP BioGRID KLK10 GeneID BioGRID Affinity Capture-MS
CAMP BioGRID XOG1 GeneID BioGRID Reconstituted Complex
CAMP BioGRID MAPK8 GeneID BioGRID Two-hybrid
CAMP Protein LBP GeneID HPRD
CAMP Protein PRTN3 GeneID HPRD
CAMP Protein FPR2 GeneID HPRD
CAMP Protein ELANE GeneID HPRD
CAMP Protein CTSG GeneID HPRD
StringDB
A B experiments database textmining combined score hadb nhadb
CAMP PGC 0 0 323 323 1 1
CAMP EGFR 0 0 681 681 1 2
CAMP HIST1H4I 0 0 207 207 1 1
CAMP FCGR1A 0 0 153 194 1 1
CAMP MYD88 0 0 470 470 1 2
CAMP HBD 0 0 556 578 1 1
CAMP DEFB103A 0 0 858 858 1 1
CAMP HIST1H4B 0 0 207 207 1 1
CAMP HIST2H2BE 0 0 218 218 1 1
CAMP LECT2 0 0 54 350 1 1
CAMP SLPI 0 0 652 669 1 1
CAMP TSLP 0 0 363 363 1 1
CAMP LAMP1 0 0 154 153 1 2
CAMP S100A1 0 0 204 204 1 1
CAMP CFTR 0 0 277 277 1 2
CAMP CD207 0 0 358 358 1 1
CAMP CYP24A1 0 0 469 469 1 1
CAMP IVL 0 0 367 367 1 1
CAMP DCN 0 0 95 151 1 2
CAMP TP53 0 0 160 159 1 2
CAMP LCN2 0 0 559 635 1 1
CAMP GNLY 0 0 516 530 1 1
CAMP LIPN 0 0 0 155 1 1
CAMP PTAFR 0 0 181 229 1 1
CAMP VNN2 0 0 0 153 1 1
CAMP NCF1 0 0 170 253 1 1
CAMP DEFA1B 0 0 402 622 1 1
CAMP CD19 0 0 189 227 1 1
CAMP SELPLG 0 0 193 232 1 1
CAMP LPP 0 0 267 267 1 1
CAMP HK3 0 0 0 183 1 1
CAMP KRT10 0 0 180 179 1 1
CAMP VSTM1 0 0 143 174 1 1
CAMP CRTAC1 0 0 53 157 1 1
CAMP CARD9 0 0 181 204 1 1
CAMP FGF7 0 0 317 317 1 1
CAMP BST1 0 0 0 153 1 1
CAMP DEFB133 0 0 218 218 1 1
CAMP CSF3 0 0 392 392 1 1
CAMP P2RX4 0 0 74 233 1 1
CAMP LMX1B 0 0 265 265 1 1
CAMP IRAK1 0 0 249 248 1 1
CAMP RAB3IL1 0 0 283 282 1 1
CAMP MUC5B 0 0 268 296 1 1
CAMP BPIFA2 0 0 252 272 1 1
CAMP CHIT1 0 0 90 159 1 1
CAMP LY86 0 0 54 279 1 1
CAMP CCL19 0 0 216 216 1 1
CAMP SFTPC 0 0 102 198 1 1
CAMP WFDC12 0 0 157 156 1 1
CAMP TGM1 0 0 193 193 1 1
CAMP CCL26 0 0 134 181 1 1
CAMP PSD 0 0 67 171 1 1
CAMP CTLA4 0 0 193 193 1 2
CAMP S100A7A 0 0 205 205 1 1
CAMP GBA 0 0 155 154 1 1
CAMP ENC1 0 0 0 208 1 1
CAMP FGR 0 0 61 169 1 1
CAMP P2RY6 0 0 160 159 1 1
CAMP PTX3 0 0 294 294 1 1
CAMP REG3G 0 0 252 259 1 1
CAMP KLK7 0 0 504 504 1 1
CAMP CD38 0 0 57 220 1 2
CAMP HIST2H4B 0 0 207 207 1 1
CAMP DEFA1 0 0 422 623 1 1
CAMP STAT3 0 0 340 340 1 2
CAMP LCP1 0 0 118 170 1 1
CAMP HBEGF 0 0 264 264 1 1
CAMP DEFA5 0 0 556 604 1 1
CAMP TXN 0 0 205 205 1 1
CAMP IFNA2 0 0 240 239 1 1
CAMP HGF 0 0 183 183 1 2
CAMP TRAF3IP2 0 0 213 213 1 1
CAMP SMYD5 0 0 0 334 1 1
CAMP SFTPD 0 0 569 569 1 1
CAMP FSTL1 0 0 217 217 1 1
CAMP RETNLB 0 0 116 150 1 1
CAMP SASH1 0 0 213 213 1 1
CAMP PECAM1 0 0 182 201 1 1
CAMP CAT 0 0 235 235 1 2
CAMP MUC5AC 0 0 284 311 1 1
CAMP CCL1 0 0 180 179 1 1
CAMP PLA2G2A 0 0 268 284 1 1
CAMP LILRA1 0 0 0 152 1 1
CAMP TREM1 0 0 194 358 1 1
CAMP TNF 0 0 637 650 1 2
CAMP ADAMTSL5 0 0 608 608 1 1
CAMP PI3 0 0 505 521 1 2
CAMP IL36G 0 0 266 266 1 1
CAMP VPS11 0 0 194 255 1 1
CAMP IGF1R 297 0 849 889 1 2
CAMP TIRAP 0 0 211 211 1 1
CAMP NT5E 0 0 166 184 1 1
CAMP IL7 0 0 189 189 1 1
CAMP DCD 0 0 681 681 1 1
CAMP IL18 0 0 470 470 1 2
CAMP IFNA1 0 0 595 595 1 1
CAMP MMP25 0 0 167 207 1 1
CAMP CD44 0 0 230 229 1 2
CAMP VDR 0 0 684 684 1 2
CAMP SIRPD 0 0 0 179 1 1
CAMP C6 0 0 72 232 1 1
CAMP STATH 0 0 203 203 1 1
CAMP IL1R1 0 0 288 288 1 1
CAMP ITGAE 0 0 218 218 1 1
CAMP IRGM 0 0 190 190 1 2
CAMP IL15 0 0 253 252 1 1
CAMP MMP3 0 0 181 181 1 1
CAMP S100A7 0 0 710 710 1 1
CAMP IL1RN 0 0 181 229 1 1
CAMP HRSP12 0 0 0 179 1 1
CAMP MMP7 0 0 235 235 1 1
CAMP PLA2G4D 0 0 460 459 1 1
CAMP ENSG00000268221 0 0 166 319 1 1
CAMP OPN1LW 0 0 0 217 1 1
CAMP PEBP1 0 0 0 150 1 1
CAMP CD209 0 0 254 254 1 1
CAMP FLG2 0 0 218 218 1 1
CAMP IL23R 0 0 267 294 1 1
CAMP APOH 0 0 94 341 1 1
CAMP NTS 0 0 84 367 1 1
CAMP SERPINB10 0 0 0 192 1 1
CAMP CBSL 0 0 84 171 1 1
CAMP SHF 0 0 112 570 1 1
CAMP MUC7 0 0 233 232 1 1
CAMP MEFV 0 0 218 240 1 1
CAMP MX1 0 0 234 234 1 1
CAMP IL1R2 0 0 81 163 1 1
CAMP NELFCD 0 0 202 202 1 1
CAMP LY75 0 0 173 197 1 1
CAMP CHI3L1 0 0 155 173 1 1
CAMP IL5 0 0 369 369 1 1
CAMP VWF 0 0 156 171 1 1
CAMP IL1RL2 0 0 375 375 1 1
CAMP IFNAR1 0 0 242 241 1 1
CAMP HIST1H4H 0 0 207 207 1 1
CAMP ENSG00000272980 0 0 459 470 1 1
CAMP IL17RC 0 0 203 203 1 1
CAMP TNFAIP3 0 0 230 229 1 2
CAMP CMKLR1 0 0 294 294 1 1
CAMP MPEG1 0 0 95 310 1 1
CAMP CLEC4A 0 0 122 174 1 1
CAMP CXCL3 0 0 245 251 1 1
CAMP ACPP 0 0 450 464 1 1
CAMP FGF2 0 0 181 181 1 2
CAMP S1PR2 0 0 73 411 1 1
CAMP DMBT1 0 0 233 261 1 1
CAMP S100A9 0 0 235 472 1 1
CAMP PRSS57 0 0 174 214 1 1
CAMP KLHL18 0 0 0 258 1 1
CAMP BCL2A1 0 0 81 187 1 1
CAMP IFI16 0 0 161 161 1 1
CAMP HIST1H4L 0 0 207 207 1 1
CAMP MMP8 0 0 283 423 1 1
CAMP OSM 0 0 134 185 1 1
CAMP F2RL1 0 0 96 191 1 1
CAMP LIPG 0 0 0 214 1 1
CAMP PLEK2 0 0 0 190 1 1
CAMP FUT4 0 0 167 167 1 1
CAMP FFAR3 0 0 194 225 1 1
CAMP IFNL1 0 0 181 181 1 1
CAMP CD80 0 0 433 446 1 2
CAMP RETN 0 0 181 339 1 1
CAMP CD6 0 0 0 353 1 1
CAMP CCL21 0 0 181 181 1 1
CAMP NLRP12 0 0 95 195 1 1
CAMP HPR 0 0 134 184 1 1
CAMP SDC4 0 0 83 150 1 1
CAMP IGF1 0 0 181 181 1 2
CAMP ITIH4 0 0 228 227 1 1
CAMP IRF7 0 0 325 341 1 1
CAMP CDK20 0 0 0 189 1 1
CAMP DEFB4A 0 0 870 870 1 1
CAMP APOB 0 0 125 185 1 2
CAMP CSF1R 0 0 137 158 1 1
CAMP TLR1 0 0 512 541 1 1
CAMP BTK 0 0 86 177 1 1
CAMP SOCS1 0 0 167 167 1 1
CAMP SPESP1 0 0 289 288 1 1
CAMP MS4A3 0 0 61 190 1 1
CAMP CCL5 0 0 460 475 1 2
CAMP APOA2 0 0 83 246 1 1
CAMP GSDMD 0 0 194 194 1 2
CAMP DEFB115 0 0 193 193 1 1
CAMP IL24 0 0 170 194 1 2
CAMP GZMM 0 0 53 178 1 1
CAMP IFNG 0 0 341 355 1 2
CAMP GPRC5A 0 0 0 334 1 1
CAMP HIST2H2AC 0 0 206 206 1 1
CAMP KLKB1 0 0 322 321 1 1
CAMP GPR32 0 0 161 161 1 1
CAMP HCAR2 0 0 123 213 1 1
CAMP CXCL10 0 0 468 468 1 2
CAMP CD1D 0 0 306 347 1 1
CAMP CFP 0 0 123 165 1 1
CAMP SIAH1 0 0 309 309 1 1
CAMP LTB4R 0 0 409 422 1 1
CAMP CXCL13 0 0 195 195 1 1
CAMP PYCARD 0 0 138 167 1 2
CAMP C5AR1 0 0 283 318 1 1
CAMP TLR9 0 0 861 866 1 2
CAMP CLEC4D 0 0 0 195 1 1
CAMP STC2 0 0 0 214 1 1
CAMP ARG2 0 0 158 157 1 1
CAMP CYP4X1 0 0 0 248 1 1
CAMP ERBB2 0 0 298 298 1 2
CAMP CD34 0 0 234 234 1 2
CAMP ENSG00000274276 0 0 83 170 1 1
CAMP NGF 0 0 138 173 1 2
CAMP AHSP 0 0 45 165 1 1
CAMP IRF3 0 0 286 286 1 2
CAMP LCE3B 0 0 212 212 1 1
CAMP KLK1 0 0 358 358 1 1
CAMP CTSC 0 0 288 288 1 1
CAMP KLK4 0 0 450 450 1 1
CAMP ANXA5 0 0 235 235 1 2
CAMP KLK2 0 0 310 309 1 1
CAMP LEAP2 0 0 339 559 1 1
CAMP CRISP3 0 0 147 234 1 1
CAMP GRPEL1 0 0 42 245 1 1
CAMP PLA2G2E 0 0 0 179 1 1
CAMP KLK15 0 0 325 325 1 1
CAMP RELA 0 800 150 826 1 2
CAMP AKT1 0 0 298 298 1 2
CAMP PPARG 0 0 165 165 1 2
CAMP CCL4L1 0 0 214 214 1 1
CAMP HIST1H4C 0 0 207 207 1 1
CAMP NFKB1 0 800 42 800 1 2
CAMP LY96 0 0 472 492 1 1
CAMP OPN1MW2 0 0 0 217 1 1
CAMP IL12RB1 0 0 160 159 1 1
CAMP CSF2 0 0 503 503 1 1
CAMP C1R 0 0 124 187 1 1
CAMP APOM 0 0 81 332 1 1
CAMP IL17C 0 0 323 323 1 1
CAMP F13A1 0 0 0 168 1 1
CAMP CARD14 0 0 278 278 1 1
CAMP TLR10 0 0 233 250 1 1
CAMP CLEC7A 0 0 358 381 1 1
CAMP KLK14 0 0 406 406 1 1
CAMP ACKR4 0 0 209 209 1 1
CAMP CASP6 0 0 0 188 1 1
CAMP KITLG 0 0 154 153 1 1
CAMP CD4 0 0 519 530 1 2
CAMP VCAM1 0 0 226 225 1 1
CAMP LCE3C 0 0 193 193 1 1
CAMP CDAN1 0 0 507 507 1 1
CAMP HIST4H4 0 0 207 207 1 1
CAMP VIP 0 0 236 236 1 1
CAMP MAP2K7 0 0 212 212 1 1
CAMP DEFB104B 0 0 557 557 1 1
CAMP ATP7A 0 0 195 195 1 1
CAMP CD1A 0 0 443 459 1 1
CAMP DEFA3 0 0 324 583 1 1
CAMP DEFB105A 0 0 392 392 1 1
CAMP NOS2 0 0 193 204 1 2
CAMP SECISBP2L 0 0 234 234 1 1
CAMP HAMP 0 0 459 459 1 1
CAMP NLRC4 0 0 262 337 1 2
CAMP CD83 0 0 235 235 1 1
CAMP CD14 0 0 124 166 1 1
CAMP PGLYRP2 0 0 124 178 1 1
CAMP PANX1 0 0 103 257 1 1
CAMP APOA1 0 0 777 777 1 1
CAMP NMI 0 0 0 250 1 1
CAMP GAPT 0 0 0 283 1 1
CAMP ESPL1 0 0 160 159 1 1
CAMP LNP1 0 0 140 235 1 1
CAMP CLEC4C 0 0 282 282 1 1
CAMP GAPDH 0 0 965 965 1 2
CAMP DNASE1 0 0 268 268 1 1
CAMP TLR4 0 0 765 772 1 2
CAMP DEFB106B 0 0 245 244 1 1
CAMP KLK3 0 0 249 248 1 1
CAMP HIST1H4D 0 0 207 207 1 1
CAMP IL32 0 0 290 290 1 1
CAMP FOXP3 0 0 298 298 1 2
CAMP CTSL 0 0 323 324 1 2
CAMP PPBP 0 0 243 309 1 1
CAMP TBK1 0 0 220 220 1 2
CAMP FGA 0 0 49 195 1 1
CAMP CXCL8 0 0 681 681 1 2
CAMP ENSG00000268500 0 0 0 214 1 1
CAMP DEFB105B 0 0 392 392 1 1
CAMP IL1B 0 0 795 803 1 2
CAMP P2RX1 0 0 88 233 1 1
CAMP RAC2 0 0 123 164 1 1
CAMP CYP27B1 0 0 601 601 1 1
CAMP RARRES2 0 0 334 334 1 1
CAMP IL4I1 0 0 69 161 1 1
CAMP HIF1A 0 0 321 321 1 2
CAMP SH2B2 0 0 0 204 1 1
CAMP TNFRSF1B 0 0 70 163 1 1
CAMP PF4 0 0 202 249 1 1
CAMP KRT17 0 0 193 193 1 1
CAMP ERAP1 0 0 150 169 1 1
CAMP F2R 0 0 134 173 1 1
CAMP FCN3 0 0 193 193 1 1
CAMP CXCR2 0 0 563 589 1 1
CAMP HBG2 0 0 44 217 1 1
CAMP C3AR1 0 0 123 155 1 1
CAMP HCAR3 0 0 0 151 1 1
CAMP MYOM2 0 0 395 395 1 1
CAMP HMGN1 0 0 158 157 1 1
CAMP SHMT2 0 0 307 307 1 1
CAMP REG3A 0 0 380 385 1 1
CAMP SPAG11B 0 0 193 193 1 1
CAMP CDCP1 0 0 0 189 1 1
CAMP FCGR3A 0 0 244 272 1 1
CAMP HTN1 0 0 380 380 1 1
CAMP CST11 0 0 207 207 1 1
CAMP BPI 0 0 653 756 1 1
CAMP PRG2 0 0 113 170 1 1
CAMP IL25 0 0 225 224 1 1
CAMP TNFSF11 0 0 218 218 1 2
CAMP C4A 0 0 202 218 1 1
CAMP RNPC3 0 0 0 188 1 1
CAMP CD163 0 0 233 261 1 1
CAMP SAA1 0 0 155 177 1 1
CAMP SPINK5 0 0 434 434 1 1
CAMP TRPV2 0 0 160 159 1 1
CAMP NLRP1 0 0 181 181 1 1
CAMP APOE 0 0 251 250 1 2
CAMP IL26 0 0 323 323 1 1
CAMP OXT 0 0 0 315 1 1
CAMP GABRA1 0 0 359 359 1 1
CAMP SRC 0 0 183 183 1 2
CAMP MMP1 0 0 218 218 1 1
CAMP HP 0 0 209 283 1 1
CAMP CD40LG 0 0 235 235 1 1
CAMP AK8 0 0 70 231 1 1
CAMP IRF8 0 0 113 156 1 1
CAMP OR5R1 0 0 248 248 1 1
CAMP CD177 0 0 126 170 1 1
CAMP RAG1 0 0 62 205 1 1
CAMP C10orf54 0 0 0 410 1 1
CAMP HIST1H4F 0 0 207 207 1 1
CAMP CXCR4 0 0 391 408 1 2
CAMP CDSN 0 0 180 179 1 1
CAMP APOC1 0 0 157 342 1 1
CAMP NTPCR 0 0 0 211 1 1
CAMP SEMG2 0 0 218 218 1 1
CAMP IL19 0 0 336 336 1 1
CAMP CORO1A 0 0 136 187 1 1
CAMP TNFRSF1A 0 0 173 173 1 1
CAMP GZMB 0 0 163 203 1 1
CAMP TLR3 0 0 653 653 1 2
CAMP OCLN 0 0 288 289 1 1
CAMP LGALS3 0 0 172 172 1 2
CAMP PLEK 0 0 0 156 1 1
CAMP TFPI2 0 0 123 207 1 1
CAMP IL17D 0 0 206 206 1 1
CAMP STAT1 0 0 260 260 1 2
CAMP RNASE1 0 0 169 169 1 1
CAMP DEFB1 0 0 805 805 1 1
CAMP PIP 0 0 150 297 1 1
CAMP DEFB125 0 0 0 243 1 1
CAMP ART1 0 0 150 165 1 1
CAMP CXCL14 0 0 193 193 1 1
CAMP CTRL 0 0 181 181 1 2
CAMP LYZ 0 0 310 356 1 1
CAMP A2M 0 0 181 196 1 1
CAMP TREML1 0 0 0 252 1 1
CAMP APOD 0 0 67 234 1 1
CAMP IL6 0 0 651 651 1 2
CAMP CLC 0 0 0 181 1 1
CAMP HRNR 0 0 171 171 1 1
CAMP STAT6 0 0 193 193 1 1
CAMP S100A6 0 0 360 360 1 1
CAMP RNASE7 0 0 739 739 1 1
CAMP IL3RA 0 0 210 210 1 1
CAMP MPO 0 0 603 690 1 2
CAMP CSF1 0 0 261 297 1 1
CAMP IL22 0 0 339 339 1 1
CAMP CBX8 0 0 92 158 1 1
CAMP ICAM1 0 0 349 349 1 2
CAMP CEBPE 0 0 157 303 1 1
CAMP DEFB124 0 0 0 248 1 1
CAMP UNC93B1 0 0 325 341 1 1
CAMP DEFB126 0 0 323 323 1 1
CAMP CNKSR2 0 0 49 194 1 1
CAMP ADSS 0 0 88 150 1 1
CAMP CYP2R1 0 0 310 309 1 1
CAMP ATG16L1 0 0 213 213 1 2
CAMP CEBPB 0 0 180 179 1 2
CAMP PTPRC 0 0 284 319 1 1
CAMP NOD2 0 0 459 514 1 2
CAMP HBE1 0 0 0 181 1 1
CAMP HCK 0 0 74 168 1 1
CAMP CXCR1 0 0 270 400 1 1
CAMP TLR5 0 0 501 501 1 1
CAMP CD5L 0 0 73 156 1 1
CAMP S100A12 0 0 325 595 1 1
CAMP PLA2G1B 0 0 295 295 1 1
CAMP HIST2H4A 0 0 207 207 1 1
CAMP PIGR 0 0 167 167 1 1
CAMP DEFB114 0 0 370 381 1 1
CAMP F10 0 0 44 192 1 1
CAMP TIMP1 0 0 143 170 1 1
CAMP KLK11 0 0 391 390 1 1
CAMP DLAT 0 0 241 272 1 1
CAMP GPR29 0 0 459 470 1 1
CAMP CCL18 0 0 162 161 1 1
CAMP CXCL12 0 0 374 374 1 2
CAMP SLC11A1 0 0 243 270 1 1
CAMP BLK 0 0 75 192 1 1
CAMP ITGAX 0 0 378 409 1 1
CAMP MRC1 0 0 211 211 1 1
CAMP CD1C 0 0 328 368 1 1
CAMP ADM 0 0 273 273 1 2
CAMP GSN 0 0 209 209 1 1
CAMP MAPK3 0 0 310 309 1 2
CAMP MMP9 0 0 391 453 1 2
CAMP B2M 0 0 155 232 1 1
CAMP CXCL5 0 0 323 348 1 1
CAMP GPR97 0 0 0 189 1 1
CAMP CYBB 0 0 259 323 1 2
CAMP CD5 0 0 82 304 1 1
CAMP HIST1H4J 0 0 207 207 1 1
CAMP FCGR2B 0 0 207 264 1 1
CAMP FPR3 0 0 486 486 1 1
CAMP DEFB118 0 0 235 235 1 1
CAMP SQSTM1 0 0 113 174 1 2
CAMP ACTB 0 0 340 340 1 2
CAMP SPINK9 0 0 261 261 1 1
CAMP KLK12 0 0 391 390 1 1
CAMP IL13 0 0 465 465 1 2
CAMP RNASE2 0 0 303 384 1 1
CAMP CD1B 0 0 385 384 1 1
CAMP SELP 0 0 244 271 1 1
CAMP INS 0 0 260 260 1 2
CAMP LIMA1 0 0 0 189 1 1
CAMP IL17B 0 0 163 163 1 1
CAMP ATG12 0 0 431 431 1 2
CAMP TMPRSS15 0 0 137 270 1 1
CAMP TNFSF13B 0 0 266 292 1 1
CAMP SELL 0 0 217 282 1 1
CAMP ETV7 0 0 0 261 1 1
CAMP ALOX5 0 0 180 333 1 1
CAMP ORM1 0 0 134 261 1 1
CAMP FPR2 213 0 988 991 1 1
CAMP HIST2H2AA 0 0 200 200 1 1
CAMP ANG 0 0 180 180 1 2
CAMP WAP7 0 0 163 164 1 1
CAMP C1S 0 0 141 202 1 1
CAMP KLK5 0 0 606 606 1 1
CAMP CD40 0 0 310 309 1 2
CAMP F3 0 0 218 218 1 1
CAMP CASP3 0 0 245 244 1 2
CAMP CEBPA 0 0 170 195 1 1
CAMP PTGS2 0 0 212 230 1 2
CAMP CCL11 0 0 193 213 1 1
CAMP CMTM2 0 0 0 151 1 1
CAMP PGLYRP1 0 0 326 696 1 1
CAMP FCN2 0 0 244 278 1 1
CAMP MASP2 0 0 114 190 1 1
CAMP CRP 0 0 377 377 1 2
CAMP MBD4 0 0 206 206 1 1
CAMP IL3 0 0 184 183 1 1
CAMP NLRP3 0 0 401 418 1 2
CAMP LBP 213 0 373 505 1 1
CAMP NPAT 0 0 413 412 1 1
CAMP HCRT 0 0 329 329 1 1
CAMP MBL2 0 0 370 370 1 1
CAMP MAPK1IP1L 0 0 161 161 1 1
CAMP HIST2H2AA3 0 0 200 200 1 1
CAMP DEXI 0 0 0 177 1 1
CAMP IL33 0 0 325 325 1 2
CAMP CXCL1 0 0 493 497 1 2
CAMP TMEM173 0 0 91 184 1 1
CAMP FUT2 0 0 96 539 1 1
CAMP NOD1 0 0 335 335 1 2
CAMP IFNA17 0 0 241 240 1 1
CAMP TYK2 0 0 193 193 1 1
CAMP HLA-DRA 800 0 0 808 1 1
CAMP BIN2 0 0 0 202 1 1
CAMP TFF3 0 0 217 428 1 1
CAMP JUN 0 800 264 846 1 2
CAMP ENSG00000173366 0 0 681 681 1 1
CAMP SERPINA1 0 0 348 372 1 2
CAMP FCN1 0 0 125 206 1 1
CAMP S1PR4 0 0 0 340 1 1
CAMP GZMA 0 0 125 156 1 1
CAMP CD86 0 0 370 428 1 1
CAMP ITGAL 0 0 357 388 1 1
CAMP DEFB123 0 0 205 205 1 1
CAMP TFIP11 0 0 0 190 1 1
CAMP PADI4 0 0 505 539 1 1
CAMP HSH2D 0 0 194 223 1 1
CAMP MFI2 0 0 0 191 1 1
CAMP DEFB104A 0 0 641 641 1 1
CAMP TRAF3 0 0 180 179 1 2
CAMP FFAR2 0 0 212 235 1 1
CAMP LILRA4 0 0 208 246 1 1
CAMP FGF23 0 0 156 155 1 1
CAMP PHF12 0 0 92 454 1 1
CAMP TLR2 0 0 660 680 1 2
CAMP CEACAM6 0 0 91 176 1 1
CAMP CYP4Z1 0 0 0 248 1 1
CAMP ANXA1 0 0 370 370 1 1
CAMP IL2 0 0 340 340 1 1
CAMP TLR6 0 0 361 379 1 1
CAMP MALSU1 0 0 0 307 1 1
CAMP MUC4 0 0 218 218 1 1
CAMP CST8 0 0 158 157 1 1
CAMP CCR3 0 0 150 187 1 1
CAMP PADI6 0 0 167 167 1 1
CAMP CASP1 0 0 455 481 1 2
CAMP CXCL6 0 0 150 181 1 1
CAMP CCL7 0 0 170 169 1 1
CAMP BECN1 0 0 212 212 1 2
CAMP CYB5R4 0 0 0 334 1 1
CAMP SDC1 0 0 165 198 1 1
CAMP POLR3F 0 0 0 188 1 1
CAMP KLK8 0 0 405 405 1 1
CAMP CCL17 0 0 246 245 1 1
CAMP AZU1 0 0 619 657 1 1
CAMP SVIL 213 0 0 213 1 1
CAMP CNPY3 0 0 234 234 1 1
CAMP RNASE3 0 0 234 372 1 1
CAMP PTH 0 0 294 294 1 1
CAMP MMP2 0 0 237 237 1 2
CAMP PADI2 0 0 321 321 1 1
CAMP ORM2 0 0 74 158 1 1
CAMP KLK9 0 0 391 390 1 1
CAMP ITGB2 0 0 203 269 1 1
CAMP DEFA6 0 0 405 469 1 1
CAMP CCL8 0 0 134 156 1 1
CAMP CD8A 0 0 460 459 1 1
CAMP SLC35B2 0 0 405 405 1 1
CAMP FCER1A 0 0 54 207 1 1
CAMP LAMP3 0 0 392 392 1 1
CAMP TNIP1 0 0 182 181 1 1
CAMP IRAK3 0 0 142 169 1 1
CAMP SIGIRR 0 0 193 193 1 1
CAMP KRT1 0 0 157 181 1 1
CAMP RNASE6 0 0 143 206 1 1
CAMP CLDN2 0 0 154 341 1 1
CAMP LTA 0 0 130 151 1 1
CAMP PAF1 0 0 51 465 1 1
CAMP CD69 0 0 124 154 1 1
CAMP CCR5 0 0 284 310 1 1
CAMP IL37 0 0 233 232 1 1
CAMP SCGB2A2 0 0 44 209 1 1
CAMP SEMG1 0 0 202 202 1 1
CAMP PPAT 0 0 0 187 1 1
CAMP IL36RN 0 0 316 315 1 1
CAMP CSTA 0 0 190 283 1 1
CAMP LRIF1 0 0 74 326 1 1
CAMP CLEC6A 0 0 123 175 1 1
CAMP CLEC9A 0 0 140 171 1 1
CAMP BPIFA3 0 0 61 155 1 1
CAMP CCRL2 0 0 457 473 1 1
CAMP IL17RA 0 0 287 304 1 1
CAMP MNDA 0 0 74 241 1 1
CAMP IL31 0 0 379 379 1 1
CAMP KLK13 0 0 392 392 1 1
CAMP GRN 0 0 181 181 1 1
CAMP PGBD1 0 0 0 303 1 1
CAMP S100A8 0 0 266 501 1 2
CAMP CCL27 0 0 244 243 1 1
CAMP EPX 0 0 148 199 1 1
CAMP CEACAM4 0 0 0 214 1 1
CAMP BPIFB1 0 0 95 576 1 1
CAMP CCR1 0 0 209 256 1 1
CAMP NCF2 0 0 93 197 1 1
CAMP PRF1 0 0 233 260 1 1
CAMP GLUD1 0 0 0 189 1 1
CAMP AK9 0 0 0 336 1 1
CAMP CMA1 0 0 324 323 1 1
CAMP CORT 0 0 142 214 1 1
CAMP FLG 0 0 469 469 1 1
CAMP LYG2 0 0 0 157 1 1
CAMP CST4 0 0 216 216 1 1
CAMP BPIFA1 0 0 390 596 1 1
CAMP P2RX7 0 0 929 929 1 2
CAMP IL22RA1 0 0 159 158 1 1
CAMP LOR 0 0 390 390 1 1
CAMP HIST2H3PS2 0 0 184 183 1 1
CAMP MTR 0 0 123 158 1 1
CAMP IFIH1 0 0 317 317 1 1
CAMP FUT1 0 0 0 642 1 1
CAMP DNASE2 0 0 157 164 1 1
CAMP LPO 0 0 213 259 1 1
CAMP DEFA4 0 0 256 822 1 1
CAMP ISG15 0 0 154 153 1 2
CAMP CD1E 0 0 434 434 1 1
CAMP CNTNAP5 0 0 0 175 1 1
CAMP CEACAM8 0 0 268 664 1 1
CAMP HTN3 0 0 260 260 1 1
CAMP SCIN 0 0 167 167 1 1
CAMP C5AR2 0 0 152 151 1 1
CAMP TBX21 0 0 150 181 1 1
CAMP CD300LB 0 0 0 183 1 1
CAMP SAA4 0 0 90 153 1 1
CAMP STMN1 0 0 112 169 1 1
CAMP CALCA 0 0 160 159 1 1
CAMP ELANE 213 0 653 798 1 1
CAMP C3 0 0 413 425 1 2
CAMP RASL11B 0 0 0 200 1 1
CAMP MAPK8 111 0 140 216 1 2
CAMP ARG1 0 0 195 275 1 2
CAMP HBG1 0 0 51 223 1 1
CAMP CCR7 0 0 245 270 1 1
CAMP TGM3 0 0 75 188 1 1
CAMP FN1 0 0 391 390 1 2
CAMP VTN 0 0 575 575 1 1
CAMP ETS1 0 0 73 166 1 1
CAMP ERVW-1 0 0 92 154 1 1
CAMP GLUD2 0 0 0 189 1 1
CAMP IL10RB 0 0 141 159 1 1
CAMP CR1 0 0 151 195 1 1
CAMP PRTN3 213 900 681 974 1 1
CAMP EGF 0 0 294 294 1 2
CAMP CYP27A1 0 0 184 183 1 1
CAMP BMP2 0 0 435 435 1 1
CAMP IL17A 0 0 606 606 1 2
CAMP OLFM4 0 0 108 177 1 1
CAMP CTSB 0 0 234 234 1 2
CAMP SPI1 0 0 161 264 1 1
CAMP HMGB1 0 0 587 587 1 2
CAMP CXCL11 0 0 252 252 1 1
CAMP IRF5 0 0 241 268 1 1
CAMP IFNB1 0 0 458 457 1 1
CAMP TLR7 0 0 595 606 1 2
CAMP SPAG11A 0 0 195 195 1 1
CAMP CYCS 0 0 171 171 1 2
CAMP LYN 0 0 143 174 1 1
CAMP ITGAM 0 0 360 427 1 1
CAMP TRAF6 0 0 240 239 1 2
CAMP ACKR2 0 0 193 193 1 1
CAMP LENG8 0 0 0 293 1 1
CAMP DSG1 0 0 181 181 1 1
CAMP CXCL9 0 0 370 370 1 1
CAMP TLR8 0 0 698 733 1 1
CAMP DEFB103B 0 0 858 858 1 1
CAMP CCR2 0 0 438 472 1 2
CAMP ATG5 0 0 247 246 1 2
CAMP RNF114 0 0 161 161 1 1
CAMP CLEC12A 0 0 0 152 1 1
CAMP IRF1 0 0 154 175 1 2
CAMP TNFAIP2 0 0 150 168 1 1
CAMP CX3CR1 0 0 161 185 1 1
CAMP ELN 0 0 234 234 1 1
CAMP EPPIN 0 0 166 167 1 1
CAMP CXCR3 0 0 243 265 1 1
CAMP LTF 0 0 322 455 1 1
CAMP PPP6R2 0 0 0 181 1 1
CAMP TYROBP 0 0 96 178 1 1
CAMP STX11 0 0 61 184 1 1
CAMP MCEMP1 0 0 0 231 1 1
CAMP MOXD1 0 0 0 189 1 1
CAMP KRT16 0 0 226 225 1 1
CAMP VEGFA 0 0 391 390 1 2
CAMP FPR1 0 0 785 799 1 1
CAMP NLRP6 0 0 170 200 1 1
CAMP IFNA21 0 0 218 218 1 1
CAMP GC 0 0 464 463 1 1
CAMP CCL2 0 0 505 505 1 2
CAMP ENSG00000268221 0 0 166 319 1 1
CAMP KNG1 0 0 294 294 1 1
CAMP DEFB106A 0 0 245 244 1 1
CAMP CD68 0 0 243 242 1 2
CAMP TERF1 0 0 0 424 1 1
CAMP SLC22A16 0 0 0 408 1 1
CAMP MRGPRX2 0 0 732 734 1 1
CAMP ALB 0 0 457 457 1 2
CAMP CEACAM3 0 0 61 229 1 1
CAMP IDO1 0 0 160 159 1 1
CAMP CD276 0 0 234 234 1 1
CAMP GAPDHS 0 0 388 388 1 1
CAMP GBA2 0 0 0 207 1 1
CAMP NFKBIA 0 0 297 297 1 2
CAMP KIT 0 0 150 165 1 2
CAMP SERPINB1 0 0 292 311 1 1
CAMP ANKRD54 0 0 217 224 1 1
CAMP SYK 0 0 211 251 1 2
CAMP KLK10 0 0 325 325 1 1
CAMP C10orf99 0 0 161 161 1 1
CAMP ANXA8 0 0 181 181 1 1
CAMP IL17F 0 0 406 406 1 1
CAMP HIST1H4K 0 0 207 207 1 1
CAMP IL4 0 0 505 505 1 1
CAMP IL27 0 0 0 240 1 1
CAMP PCP4 0 0 166 165 1 1
CAMP MSRB2 0 0 189 200 1 1
CAMP FCGR2A 0 0 325 350 1 1
CAMP HIST1H4A 0 0 207 207 1 1
CAMP GPR123 0 0 0 252 1 1
CAMP IL9 0 0 209 209 1 1
CAMP F7 0 0 0 190 1 1
CAMP MAPK14 0 0 295 295 1 2
CAMP MGEA5 0 0 160 159 1 1
CAMP CFL1 0 0 107 158 1 1
CAMP FOLR3 0 0 0 165 1 1
CAMP CLEC4E 0 0 153 194 1 1
CAMP APMAP 0 0 57 201 1 1
CAMP SCARA5 0 0 0 189 1 1
CAMP NCF4 0 0 95 199 1 1
CAMP DEFB4B 0 0 744 744 1 1
CAMP CDH1 0 0 181 181 1 2
CAMP MB21D1 0 0 279 279 1 1
CAMP DNASE1L3 0 0 245 244 1 1
CAMP THBD 0 0 173 173 1 1
CAMP PADI3 0 0 165 165 1 1
CAMP MTRR 0 0 207 207 1 1
CAMP IL23A 0 0 261 261 1 1
CAMP MARCO 0 0 445 466 1 1
CAMP PLG 0 0 283 282 1 1
CAMP CTSD 0 0 193 193 1 2
CAMP DDX58 0 0 375 375 1 1
CAMP AIM2 0 0 391 404 1 2
CAMP C4B 0 0 199 215 1 1
CAMP FCGR3B 0 0 242 347 1 1
CAMP CCL22 0 0 227 226 1 1
CAMP LALBA 0 0 71 167 1 1
CAMP CTSG 213 0 661 766 1 1
CAMP CCL3 0 0 382 410 1 1
CAMP KLK6 0 0 391 390 1 1
CAMP HIST1H4E 0 0 207 207 1 1
CAMP PLA2G10 0 0 227 226 1 1
CAMP AGER 0 0 335 351 1 2
CAMP CCR10 0 0 213 213 1 1
CAMP LITAF 0 0 48 220 1 1
CAMP HRG 0 0 135 154 1 1
CAMP CCL23 0 0 142 173 1 1
CAMP NR1H4 0 0 103 200 1 1
CAMP SKAP2 0 0 184 309 1 1
CAMP IL1A 0 0 457 457 1 1
CAMP ATG7 0 0 95 151 1 2
CAMP TFPI 0 0 181 306 1 1
CAMP CCL4 0 0 324 354 1 1
CAMP TF 0 0 108 155 1 2
CAMP CRYGC 0 0 216 216 1 1
CAMP TAC1 0 0 281 281 1 1
CAMP SRGN 0 0 112 208 1 1
CAMP TJP1 0 0 260 272 1 1
CAMP SPACA3 0 0 154 161 1 1
CAMP SELE 0 0 210 210 1 1
CAMP MAVS 0 0 229 228 1 2
CAMP CXCL2 0 0 414 418 1 1
CAMP IRAK4 0 0 232 231 1 1
CAMP REXO2 0 0 0 190 1 1
CAMP ST5 0 0 376 376 1 1
CAMP CCL20 0 0 557 557 1 1
CAMP HBB 0 0 423 444 1 1
CAMP IL10 0 0 565 565 1 2
Ontologies
ID Category Term Effect Evidence PubMed
GO:0001530 Molecular Function lipopolysaccharide binding enables IBA
GO:0005515 Molecular Function protein binding enables IPI
GO:1990000 Biological Process amyloid fibril formation involved_in EXP
GO:1990000 Biological Process amyloid fibril formation involved_in IDA
GO:0019731 Biological Process antibacterial humoral response involved_in IDA
GO:0061844 Biological Process antimicrobial humoral immune response mediated by antimicrobial peptide involved_in IBA
GO:0061844 Biological Process antimicrobial humoral immune response mediated by antimicrobial peptide involved_in IDA
GO:0071347 Biological Process cellular response to interleukin-1 involved_in IEA
GO:0071354 Biological Process cellular response to interleukin-6 involved_in IEA
GO:0071222 Biological Process cellular response to lipopolysaccharide involved_in IEA
GO:0071224 Biological Process cellular response to peptidoglycan involved_in IEA
GO:0071356 Biological Process cellular response to tumor necrosis factor involved_in IEA
GO:0019835 Biological Process cytolysis involved_in EXP
GO:0050829 Biological Process defense response to Gram-negative bacterium involved_in IBA
GO:0050830 Biological Process defense response to Gram-positive bacterium involved_in IBA
GO:0050830 Biological Process defense response to Gram-positive bacterium involved_in IDA
GO:0042742 Biological Process defense response to bacterium acts_upstream_of_or_within IMP
GO:0045087 Biological Process innate immune response involved_in IBA
GO:0002227 Biological Process innate immune response in mucosa involved_in IDA
GO:0051873 Biological Process killing by host of symbiont cells acts_upstream_of_or_within IDA
GO:0051873 Biological Process killing by host of symbiont cells involved_in IDA
GO:0042119 Biological Process neutrophil activation involved_in IDA
GO:0045766 Biological Process positive regulation of angiogenesis involved_in IEA
GO:0008284 Biological Process positive regulation of cell population proliferation involved_in IEA
GO:0001934 Biological Process positive regulation of protein phosphorylation involved_in IEA
GO:0042995 Cellular Component cell projection located_in IEA
GO:0070062 Cellular Component extracellular exosome located_in HDA
GO:0005576 Cellular Component extracellular region located_in TAS
GO:0005615 Cellular Component extracellular space is_active_in IBA
GO:0005615 Cellular Component extracellular space located_in IDA
GO:0042581 Cellular Component specific granule located_in IDA
GO:0035580 Cellular Component specific granule lumen located_in TAS
GO:1904724 Cellular Component tertiary granule lumen located_in TAS
Pathways
Name DB ID
Innate Immune System Reactome R-HSA-168249
Immune System Reactome R-HSA-168256
Neutrophil degranulation Reactome R-HSA-6798695
Antimicrobial peptides Reactome R-HSA-6803157
Sterol regulatory element-binding proteins (SREBP) signaling (WP1982) WikiPathways WP1982_r116442
Vitamin D receptor pathway (WP2877) WikiPathways WP2877_r119905
Non-genomic actions of 1,25 dihydroxyvitamin D3 (WP4341) WikiPathways WP4341_r122900
Transcripts
Accession Version MolecularType Name NCBI Comments
NM_004345 5 mRNA None NC_000003 Reference