SPNS1

SPNS lysolipid transporter 1, lysophospholipid
General Information
Name SPNS lysolipid transporter 1, lysophospholipid
Alias
  • protein spinster homolog 1
  • SPNS sphingolipid transporter 1 (putative)
  • spinster homolog 1
  • spinster-like protein 1
Synonyms HSpin1 nrs SPINL PP2030 SPIN1 LAT SLC63A1 SLC62A1
Gene_family Solute carriers
organism Homo sapiens
entrez_id 83985
location 16p11.2
transcript_count 9
exon_count 14
Cross References
Location
by NCBI GRCh38.p14
    Summary
      Entrez Predicted to enable transmembrane transporter activity. Predicted to be involved in lysophospholipid transport and phospholipid efflux. Predicted to act upstream of or within regulation of lysosomal lumen pH. Located in lysosomal membrane. [provided by Alliance of Genome Resources, Mar 2025]
      Stringdb Protein spinster homolog 1; Sphingolipid transporter (By similarity). May be involved in necrotic or autophagic cell death
      nextProt Sphingolipid transporter (By similarity). May be involved in necrotic or autophagic cell death.
    Interactions
    NCBI
    A A.Source B B.DB B.Source Description PubMed
    SPNS1 BioGRID CDC123 GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID MECP2 GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID RPA3 GeneID BioGRID Proximity Label-MS
    SPNS1 BioGRID CLEC16A GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID EGFR GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID FLT4 GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID NTRK3 GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID NTRK1 GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID POMK GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID PRKN GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID CUL3 GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID PLD3 GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID RHOH GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID RHOA GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID TMEM192 GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID M GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID TMPRSS11B GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID ACE2 GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID FURIN GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID P2RY8 GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID ARMC6 GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID OPALIN GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID CA10 GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID SPPL2B GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID KLK15 GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID GPRC5B GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID CLEC2D GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID CLEC4E GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID VSIG4 GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID GPR182 GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID RAMP3 GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID SYNGR1 GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID KLRB1 GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID IL12RB1 GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID HLA-DQA1 GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID HLA-B GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID GZMH GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID FFAR1 GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID TNFSF8 GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID AUP1 GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID AQP3 GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID LAMTOR1 GeneID BioGRID Proximity Label-MS
    SPNS1 BioGRID COIL GeneID BioGRID Proximity Label-MS
    SPNS1 BioGRID TP53 GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID LAMP2 GeneID BioGRID Proximity Label-MS
    SPNS1 BioGRID ARF6 GeneID BioGRID Proximity Label-MS
    SPNS1 BioGRID MAP3K15 GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID SEC63 GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID RRBP1 GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID ORF7b GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID ORF7b GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID E5 GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID E5b GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID E5a GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID NPC1 GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID HSCB GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID FAM120C GeneID BioGRID Proximity Label-MS
    SPNS1 BioGRID FAM120A GeneID BioGRID Proximity Label-MS
    SPNS1 BioGRID CCR9 GeneID BioGRID Two-hybrid
    SPNS1 BioGRID HTR2C GeneID BioGRID Two-hybrid
    SPNS1 BioGRID FASN GeneID BioGRID Negative Genetic
    SPNS1 BioGRID CCR8 GeneID BioGRID Two-hybrid
    SPNS1 BioGRID CHRM5 GeneID BioGRID Two-hybrid
    SPNS1 BioGRID BDKRB2 GeneID BioGRID Two-hybrid
    SPNS1 BioGRID ADORA2A GeneID BioGRID Two-hybrid
    SPNS1 BioGRID PLEKHA4 GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID CLUAP1 GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID DUSP7 GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID CYB5B GeneID BioGRID Co-fractionation
    SPNS1 BioGRID NPTN GeneID BioGRID Co-fractionation
    SPNS1 BioGRID NR2C2 GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID RC3H1 GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID ARMC8 GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID TES GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID Cep152 GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID Rab5c GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID CLN5 GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID UNC93B1 GeneID BioGRID Affinity Capture-MS
    SPNS1 BioGRID NLRX1 GeneID BioGRID Affinity Capture-MS
    SPNS1 None BCL2L1 GeneID HPRD None
    SPNS1 None BCL2 GeneID HPRD None
    SPNS1 BioGRID BCL2L1 GeneID BioGRID Affinity Capture-Western
    SPNS1 BioGRID BCL2 GeneID BioGRID Affinity Capture-Western
    StringDB
    A B experiments database textmining combined score hadb nhadb
    SPNS1 TSSC1 0 0 276 319 1 1
    SPNS1 ATG9A 0 0 113 164 1 2
    SPNS1 SLC46A1 0 0 90 179 1 1
    SPNS1 PIP5K1B 0 0 193 212 1 1
    SPNS1 HIATL1 0 0 334 487 1 1
    SPNS1 CLEC16A 0 0 0 190 1 2
    SPNS1 ASS1 0 0 0 187 1 1
    SPNS1 MPV17L2 0 0 123 161 1 1
    SPNS1 S100A11 0 0 95 178 1 1
    SPNS1 SLC11A2 0 0 0 158 1 1
    SPNS1 NLRX1 157 0 101 209 1 1
    SPNS1 TES 270 0 0 270 1 1
    SPNS1 UBALD1 0 0 157 164 1 1
    SPNS1 CORO2B 0 0 0 155 1 1
    SPNS1 PARP14 0 0 124 166 1 1
    SPNS1 SMC1A 0 0 95 164 1 1
    SPNS1 AASDH 0 0 0 165 1 1
    SPNS1 GTF2F1 0 0 166 182 1 1
    SPNS1 NCKIPSD 0 0 202 214 1 1
    SPNS1 SLC44A2 0 0 57 170 1 1
    SPNS1 EIF2AK2 0 0 0 183 1 2
    SPNS1 MYLPF 0 0 91 193 1 1
    SPNS1 FLVCR2 0 0 134 236 1 1
    SPNS1 CHKA 0 0 0 156 1 1
    SPNS1 TUFM 0 0 600 633 1 1
    SPNS1 MFSD5 0 0 324 448 1 1
    SPNS1 PRRT2 0 0 113 156 1 1
    SPNS1 CYCS 160 0 398 517 1 1
    SPNS1 GRHL3 0 0 86 224 1 1
    SPNS1 TECR 0 0 0 196 1 1
    SPNS1 CLUH 0 0 0 189 1 1
    SPNS1 HKDC1 0 0 161 389 1 1
    SPNS1 TMEM180 0 0 322 475 1 1
    SPNS1 BBS7 0 0 137 160 1 1
    SPNS1 ATP2A1 0 0 415 444 1 1
    SPNS1 SLC6A18 0 0 75 161 1 1
    SPNS1 MFSD12 0 0 118 231 1 1
    SPNS1 MAP3K11 0 0 0 159 1 1
    SPNS1 RBM19 0 0 234 357 1 1
    SPNS1 CTH 0 0 0 158 1 1
    SPNS1 RAB10 0 0 0 213 1 1
    SPNS1 C6orf222 0 0 504 582 1 1
    SPNS1 FHOD1 0 0 150 281 1 1
    SPNS1 MLIP 0 0 240 287 1 1
    SPNS1 SLC22A6 0 0 0 152 1 1
    SPNS1 MFSD6 0 0 255 505 1 1
    SPNS1 LAMP1 0 0 124 178 1 2
    SPNS1 RASEF 0 0 0 213 1 1
    SPNS1 LRIG1 0 0 0 294 1 1
    SPNS1 IMPDH2 0 0 135 167 1 1
    SPNS1 UBR5 0 0 103 207 1 1
    SPNS1 RAB8A 0 0 0 213 1 2
    SPNS1 KLF10 0 0 87 174 1 1
    SPNS1 ENSG00000261832 0 0 369 460 1 1
    SPNS1 SLC15A4 0 0 48 152 1 1
    SPNS1 SLC35D2 0 0 96 156 1 1
    SPNS1 SLC12A4 0 0 0 181 1 1
    SPNS1 PCDHGA2 0 0 293 304 1 1
    SPNS1 MOAP1 0 0 170 169 1 1
    SPNS1 SLC12A9 0 0 94 168 1 1
    SPNS1 LRIG3 0 0 0 173 1 1
    SPNS1 RAB40B 0 0 0 213 1 1
    SPNS1 ATP13A1 0 0 81 162 1 1
    SPNS1 CLUAP1 270 0 0 270 1 1
    SPNS1 SDHB 160 0 0 200 1 1
    SPNS1 TERF2 0 0 218 297 1 1
    SPNS1 SLC12A7 0 0 0 181 1 1
    SPNS1 RAB40AL 0 0 0 213 1 1
    SPNS1 XPOT 0 0 180 249 1 1
    SPNS1 S1PR3 0 0 54 155 1 1
    SPNS1 DDOST 0 0 0 210 1 1
    SPNS1 SLC22A8 0 0 0 152 1 1
    SPNS1 SLC44A3 0 0 73 185 1 1
    SPNS1 PPP4C 0 0 122 173 1 1
    SPNS1 SRSF9 0 0 0 154 1 1
    SPNS1 SULT1A2 0 0 329 340 1 1
    SPNS1 LRRC40 0 0 134 156 1 1
    SPNS1 CHUK 0 0 0 160 1 1
    SPNS1 BMPR1B 0 0 0 193 1 1
    SPNS1 CAPN10 0 0 135 167 1 2
    SPNS1 PNISR 0 0 193 340 1 1
    SPNS1 SLC11A1 0 0 86 198 1 1
    SPNS1 COL9A2 0 0 124 246 1 1
    SPNS1 SSPN 0 0 258 258 1 1
    SPNS1 MFSD11 0 0 321 470 1 1
    SPNS1 RGN 0 0 128 171 1 1
    SPNS1 RPS10-NUDT3 0 0 466 477 1 1
    SPNS1 ATG4D 0 0 0 156 1 2
    SPNS1 PLEKHM1 0 0 134 153 1 2
    SPNS1 ELP4 0 0 210 210 1 1
    SPNS1 NR2C2 270 0 0 281 1 1
    SPNS1 SLC46A3 0 0 90 183 1 1
    SPNS1 LRRK2 0 0 0 159 1 2
    SPNS1 KIAA1919 0 0 256 422 1 1
    SPNS1 ATP6V0A4 0 0 143 314 1 1
    SPNS1 UGP2 0 0 0 180 1 1
    SPNS1 GNAI3 0 0 167 167 1 2
    SPNS1 PITRM1 0 0 210 398 1 1
    SPNS1 SMPX 0 0 194 304 1 1
    SPNS1 MCF2L 0 0 167 224 1 1
    SPNS1 SH2B1 0 0 596 605 1 1
    SPNS1 CDK9 0 0 122 195 1 1
    SPNS1 SLC44A5 0 0 92 201 1 1
    SPNS1 KCTD13 0 0 293 315 1 1
    SPNS1 MFSD8 0 0 181 505 1 1
    SPNS1 SLC7A14 0 0 82 158 1 1
    SPNS1 TGFBR1 0 0 0 193 1 1
    SPNS1 WDFY4 0 0 0 236 1 1
    SPNS1 NIPAL4 0 0 0 151 1 1
    SPNS1 SMC1B 0 0 0 259 1 1
    SPNS1 ASAH2B 0 0 0 156 1 1
    SPNS1 ECI1 0 0 180 320 1 1
    SPNS1 SEZ6L2 0 0 135 189 1 1
    SPNS1 RAB13 0 0 0 213 1 2
    SPNS1 CLPB 0 0 0 170 1 1
    SPNS1 CLIC4 0 0 112 177 1 1
    SPNS1 GABARAP 0 0 122 234 1 2
    SPNS1 EIF3C 0 0 178 177 1 1
    SPNS1 ATG7 0 0 165 216 1 2
    SPNS1 SLC44A1 0 0 49 163 1 1
    SPNS1 FMN1 0 0 0 175 1 1
    SPNS1 PTGR1 0 0 157 157 1 1
    SPNS1 CTSD 0 0 605 628 1 2
    SPNS1 ENSG00000267261 0 0 0 155 1 1
    SPNS1 CD19 0 0 166 165 1 1
    SPNS1 WDR6 0 0 236 236 1 1
    SPNS1 HIATL2 0 0 0 262 1 1
    SPNS1 SSBP1 0 0 0 150 1 1
    SPNS1 MYCBP2 0 0 112 253 1 1
    SPNS1 HOXC12 0 0 170 169 1 1
    SPNS1 UAP1 0 0 0 180 1 1
    SPNS1 APOBR 0 0 384 384 1 1
    SPNS1 CROCC 0 0 150 181 1 1
    SPNS1 RHEB 0 0 71 160 1 2
    SPNS1 DAGLA 0 0 0 189 1 1
    SPNS1 SIX1 0 0 74 153 1 1
    SPNS1 MFSD10 0 0 376 533 1 1
    SPNS1 TUBGCP6 0 0 194 278 1 1
    SPNS1 TECRL 0 0 82 268 1 1
    SPNS1 WDFY3 0 0 0 236 1 2
    SPNS1 PLEKHA4 270 0 0 270 1 1
    SPNS1 RAB40A 0 0 0 213 1 1
    SPNS1 IMMP1L 0 0 275 290 1 1
    SPNS1 ITM2B 0 0 138 184 1 1
    SPNS1 CCDC101 0 0 451 451 1 1
    SPNS1 SLC29A4 0 0 103 159 1 1
    SPNS1 ACVR1B 0 0 0 193 1 1
    SPNS1 GLTPD2 0 0 206 211 1 1
    SPNS1 BCL6 0 0 53 178 1 1
    SPNS1 SLC12A6 0 0 0 181 1 1
    SPNS1 GP2 0 0 183 307 1 1
    SPNS1 CDAN1 0 0 203 259 1 1
    SPNS1 ATP7A 0 0 0 154 1 1
    SPNS1 MBTPS1 0 0 0 271 1 1
    SPNS1 PIGO 0 0 212 286 1 1
    SPNS1 CORO2A 0 0 0 155 1 1
    SPNS1 MDH2 0 0 88 178 1 1
    SPNS1 PRMT5 0 0 70 177 1 1
    SPNS1 HIAT1 0 0 323 446 1 1
    SPNS1 ACOT9 0 0 219 356 1 1
    SPNS1 SLC15A5 0 0 120 216 1 1
    SPNS1 ENSG00000268465 0 0 182 199 1 1
    SPNS1 CORO1A 0 0 134 237 1 1
    SPNS1 BNIP1 0 0 150 188 1 2
    SPNS1 RABEP2 0 0 605 605 1 1
    SPNS1 PAPD7 0 0 261 269 1 1
    SPNS1 MFSD6L 0 0 358 469 1 1
    SPNS1 ZRANB2 0 0 180 242 1 1
    SPNS1 UAP1L1 0 0 0 233 1 1
    SPNS1 UNC93B1 157 0 211 436 1 1
    SPNS1 OCA2 0 0 171 278 1 1
    SPNS1 GABARAPL1 0 0 0 164 1 2
    SPNS1 SLC44A4 0 0 47 162 1 1
    SPNS1 SGPL1 0 0 103 188 1 1
    SPNS1 INO80B 0 0 230 229 1 1
    SPNS1 SETD3 0 0 155 294 1 1
    SPNS1 AK2 0 0 122 214 1 1
    SPNS1 ORMDL3 0 0 137 175 1 1
    SPNS1 SNCA 0 0 0 155 1 2
    SPNS1 FAM120A 273 0 0 273 1 1
    SPNS1 SLC22A18 0 0 0 192 1 1
    SPNS1 HDLBP 0 0 157 304 1 1
    SPNS1 ATP5B 0 0 89 150 1 1
    SPNS1 SLC35C2 0 0 97 158 1 1
    SPNS1 DZIP1 0 0 212 294 1 1
    SPNS1 SLC35E1 0 0 107 166 1 1
    SPNS1 GSDMB 0 0 151 150 1 1
    SPNS1 MFSD7 0 0 107 253 1 1
    SPNS1 MFSD2A 0 0 140 208 1 1
    SPNS1 ACVR1 0 0 0 272 1 1
    SPNS1 RAB8B 0 0 0 213 1 2
    SPNS1 MFSD9 0 0 517 610 1 1
    SPNS1 ABCB6 0 0 0 167 1 1
    SPNS1 SLC46A2 0 0 103 250 1 1
    SPNS1 MFSD3 0 0 310 441 1 1
    SPNS1 ARHGEF40 0 0 241 240 1 1
    SPNS1 CTNS 0 0 0 206 1 1
    SPNS1 SULT1A4 0 0 414 424 1 1
    SPNS1 MRPL41 0 0 233 232 1 1
    SPNS1 RC3H1 270 0 0 270 1 1
    SPNS1 ABCA1 0 0 44 279 1 1
    SPNS1 ELOF1 0 0 181 203 1 1
    SPNS1 PRIMPOL 0 0 459 640 1 1
    SPNS1 UNC45B 0 0 155 280 1 1
    SPNS1 NXF1 0 0 0 188 1 1
    SPNS1 AKTIP 0 0 0 165 1 1
    SPNS1 OR4Q3 0 0 260 260 1 1
    SPNS1 TXK 0 0 96 163 1 1
    SPNS1 SKOR1 0 0 205 205 1 1
    SPNS1 LRIG2 0 0 0 173 1 1
    SPNS1 SNX14 0 0 181 227 1 1
    SPNS1 SIAH2 0 0 0 177 1 1
    SPNS1 FAM120C 172 0 0 171 1 1
    SPNS1 SLC12A5 0 0 0 181 1 1
    SPNS1 GART 0 0 0 298 1 1
    SPNS1 ATP6V0C 0 0 149 302 1 2
    SPNS1 CFTR 0 0 108 161 1 1
    SPNS1 BNIP2 0 0 164 168 1 1
    SPNS1 ARMC8 270 0 0 276 1 1
    SPNS1 SRSF6 0 0 96 249 1 1
    SPNS1 SRSF1 0 0 75 269 1 1
    SPNS1 HGS 0 0 0 247 1 2
    SPNS1 SCGB3A1 0 0 154 153 1 1
    SPNS1 GLI4 0 0 260 281 1 1
    SPNS1 G3BP2 0 0 0 190 1 1
    SPNS1 LGI4 0 0 0 210 1 1
    SPNS1 HSCB 270 0 0 291 1 1
    SPNS1 XKR6 0 0 204 204 1 1
    SPNS1 TSFM 0 0 149 173 1 1
    SPNS1 MSRA 0 0 124 213 1 1
    SPNS1 NPC1 0 0 131 210 1 2
    SPNS1 ELL3 0 0 234 343 1 1
    SPNS1 CORO6 0 0 0 155 1 1
    SPNS1 SVOP 0 0 402 523 1 1
    SPNS1 PTPMT1 0 0 181 181 1 1
    SPNS1 S1PR2 0 0 108 202 1 1
    SPNS1 KCNAB3 0 0 207 255 1 1
    SPNS1 SIAH1 0 0 0 177 1 1
    SPNS1 CRACR2A 0 0 0 213 1 1
    SPNS1 NFATC2IP 0 0 556 572 1 1
    SPNS1 PSMB1 0 0 0 277 1 1
    SPNS1 BRSK2 0 0 150 235 1 1
    SPNS1 MYADM 0 0 195 210 1 1
    SPNS1 GABARAPL2 0 0 57 169 1 2
    SPNS1 UHRF1BP1L 0 0 122 172 1 1
    SPNS1 NDUFV2 0 0 128 246 1 1
    SPNS1 SVOPL 0 0 391 276 1 1
    SPNS1 APOM 0 0 0 248 1 1
    SPNS1 BCL2L1 270 0 415 554 1 2
    SPNS1 RNPS1 0 0 143 339 1 1
    SPNS1 ZNF500 0 0 287 307 1 1
    SPNS1 GANAB 0 0 150 297 1 1
    SPNS1 MUSTN1 0 0 210 210 1 1
    SPNS1 CYHR1 0 0 0 157 1 1
    SPNS1 CLN3 0 0 358 466 1 2
    SPNS1 ACVR1C 0 0 0 193 1 1
    SPNS1 NUPL1 0 0 184 253 1 1
    SPNS1 DOCK7 0 0 142 153 1 1
    SPNS1 RAB12 0 0 0 223 1 2
    SPNS1 LYRM2 0 0 284 284 1 1
    SPNS1 SULT1A1 0 0 341 352 1 1
    SPNS1 MFSD1 0 0 407 467 1 1
    SPNS1 TXNRD1 0 0 0 160 1 1
    SPNS1 KANSL1 0 0 183 183 1 1
    SPNS1 ABCA7 0 0 0 221 1 1
    SPNS1 DNAJC10 0 0 0 196 1 1
    SPNS1 BECN1 0 0 120 158 1 2
    SPNS1 ABCB1 0 0 55 172 1 1
    SPNS1 ABCC1 0 0 74 402 1 1
    SPNS1 COL9A1 0 0 113 224 1 1
    SPNS1 UNC93A 0 0 428 581 1 1
    SPNS1 YPEL3 0 0 203 215 1 1
    SPNS1 SLC35B3 0 0 94 155 1 1
    SPNS1 SV2A 0 0 253 308 1 1
    SPNS1 ASAH2 0 0 0 156 1 1
    SPNS1 CORO1C 0 0 0 155 1 1
    SPNS1 ITFG1 0 0 0 210 1 1
    SPNS1 TBC1D25 0 0 226 225 1 1
    SPNS1 CYTH2 0 0 155 173 1 1
    SPNS1 ACVRL1 0 0 0 172 1 1
    SPNS1 MFSD4 0 0 414 566 1 1
    SPNS1 AMDHD2 0 0 0 164 1 1
    SPNS1 HS1BP3 0 0 325 392 1 2
    SPNS1 SPHK2 0 0 0 310 1 1
    SPNS1 TEAD4 0 0 95 157 1 1
    SPNS1 SLC15A3 0 0 53 156 1 1
    SPNS1 SPHK1 0 0 0 388 1 2
    SPNS1 RAB15 0 0 0 213 1 1
    SPNS1 RPL27A 0 0 136 288 1 1
    SPNS1 TBX6 0 0 142 168 1 1
    SPNS1 CHCHD3 0 0 170 260 1 1
    SPNS1 AIRE 0 0 0 236 1 1
    SPNS1 CSRP1 0 0 150 291 1 1
    SPNS1 CHKB 0 0 0 169 1 1
    SPNS1 AMBRA1 0 0 112 208 1 2
    SPNS1 ABCB7 0 0 0 165 1 1
    SPNS1 CORO1B 0 0 0 155 1 1
    SPNS1 YARS 0 0 0 183 1 1
    SPNS1 BMPR1A 0 0 0 193 1 1
    SPNS1 TMEM86A 0 0 322 330 1 1
    SPNS1 UBASH3A 0 0 142 183 1 1
    SPNS1 ATP7B 0 0 0 154 1 1
    SPNS1 NIPA2 0 0 0 167 1 1
    SPNS1 TEAD1 0 0 93 190 1 1
    SPNS1 ABCG2 0 0 53 191 1 1
    SPNS1 RAB44 0 0 0 213 1 1
    SPNS1 DAGLB 0 0 0 189 1 1
    SPNS1 SPG11 0 0 134 169 1 1
    SPNS1 MYOZ2 0 0 134 223 1 1
    SPNS1 CDIPT 0 0 143 202 1 1
    SPNS1 BMPR2 0 0 0 208 1 1
    SPNS1 CLN5 270 0 143 439 1 1
    SPNS1 SV2B 0 0 284 373 1 1
    SPNS1 SLC35A5 0 0 102 160 1 1
    SPNS1 AVEN 0 0 283 282 1 1
    SPNS1 KIF22 0 0 139 196 1 1
    SPNS1 BCL2 270 0 0 270 1 2
    SPNS1 ACOT8 0 0 181 195 1 1
    SPNS1 ALDH18A1 0 0 0 333 1 1
    SPNS1 ATXN2L 0 0 605 609 1 1
    SPNS1 ZFYVE26 0 0 166 165 1 1
    SPNS1 NIPAL1 0 0 0 167 1 1
    SPNS1 USP19 131 0 0 150 1 1
    SPNS1 G3BP1 0 0 0 190 1 1
    SPNS1 SV2C 0 0 323 442 1 1
    SPNS1 RAB7A 0 0 95 176 1 2
    SPNS1 FRMD5 0 0 118 154 1 1
    SPNS1 TAP1 0 0 134 173 1 1
    SPNS1 LRRC14 0 0 366 410 1 1
    SPNS1 IKBKB 0 0 0 203 1 1
    SPNS1 SLC36A1 0 0 214 237 1 1
    SPNS1 CELSR3 0 0 123 155 1 1
    SPNS1 SLC25A3 0 0 170 267 1 1
    SPNS1 RAB40C 0 0 0 213 1 1
    SPNS1 RRM1 0 0 0 157 1 1
    SPNS1 SYNJ2 0 0 134 178 1 1
    SPNS1 RAB28 0 0 0 213 1 1
    SPNS1 CLCN7 0 0 219 290 1 1
    SPNS1 GHITM 0 0 125 183 1 1
    SPNS1 NPIPB8 0 0 224 224 1 1
    SPNS1 MYBPC1 0 0 161 244 1 1
    SPNS1 H6PD 0 0 0 195 1 1
    SPNS1 SUOX 0 0 157 156 1 1
    SPNS1 EIF2AK3 0 0 0 183 1 2
    SPNS1 SLC29A3 0 0 105 171 1 1
    SPNS1 USP2 0 0 96 234 1 1
    SPNS1 SIAH3 0 0 0 157 1 1
    Ontologies
    ID Category Term Effect Evidence PubMed
    GO:0005515 Molecular Function protein binding enables IPI
    GO:0022857 Molecular Function transmembrane transporter activity enables IBA
    GO:0051977 Biological Process lysophospholipid transport involved_in IBA
    GO:0033700 Biological Process phospholipid efflux involved_in IBA
    GO:0035751 Biological Process regulation of lysosomal lumen pH involved_in IEA
    GO:0055085 Biological Process transmembrane transport involved_in IEA
    GO:0005765 Cellular Component lysosomal membrane located_in HDA
    GO:0016020 Cellular Component membrane is_active_in IBA
    GO:0005743 Cellular Component mitochondrial inner membrane located_in IEA
    Pathways
    Name DB ID
    16p11.2 distal deletion syndrome (WP4950) WikiPathways WP4950_r115784
    Transcripts
    Accession Version MolecularType Name NCBI Comments
    XM_047434739 1 mRNA transcript variant X1 NC_000016 Reference
    XM_047434741 1 mRNA transcript variant X4 NC_000016 Reference
    NM_032038 3 mRNA transcript variant 1 NC_000016 Reference
    NM_001142451 2 mRNA transcript variant 4 NC_000016 Reference
    NM_001142449 2 mRNA transcript variant 5 NC_000016 Reference
    NM_001142450 2 mRNA transcript variant 3 NC_000016 Reference
    NM_001142448 2 mRNA transcript variant 2 NC_000016 Reference
    XM_006721096 5 mRNA transcript variant X3 NC_000016 Reference
    XM_047434740 1 mRNA transcript variant X2 NC_000016 Reference