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CASP8

caspase 8
General Information
Name caspase 8
Alias
  • caspase-8
  • FADD-homologous ICE/CED-3-like protease
  • FADD-like ICE
  • ICE-like apoptotic protease 5
  • MACH-alpha-1/2/3 protein
  • MACH-beta-1/2/3/4 protein
  • MORT1-associated ced-3 homolog
  • apoptotic cysteine protease
  • apoptotic protease Mch-5
  • caspase 8, apoptosis-related cysteine peptidase
  • caspase 8, apoptosis-related cysteine protease
Gene_family Caspases|Death effector domain containing|Death inducing signaling complex |Ripoptosome
organism Homo sapiens
entrez_id 841
location 2q33.1
transcript_count 70
exon_count 16
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This protein is involved in the programmed cell death induced by Fas and various apoptotic stimuli. The N-terminal FADD-like death effector domain of this protein suggests that it may interact with Fas-interacting protein FADD. This protein was detected in the insoluble fraction of the affected brain region from Huntington disease patients but not in those from normal controls, which implicated the role in neurodegenerative diseases. Many alternatively spliced transcript variants encoding different isoforms have been described, although not all variants have had their full-length sequences determined. [provided by RefSeq, Jul 2008]
    Stringdb Caspase-8; Most upstream protease of the activation cascade of caspases responsible for the TNFRSF6/FAS mediated and TNFRSF1A induced cell death. Binding to the adapter molecule FADD recruits it to either receptor. The resulting aggregate called death- inducing signaling complex (DISC) performs CASP8 proteolytic activation. The active dimeric enzyme is then liberated from the DISC and free to activate downstream apoptotic proteases. Proteolytic fragments of the N-terminal propeptide (termed CAP3, CAP5 and CAP6) are likely retained in the DISC. Cleaves and activates CASP3, CASP4, CASP6, [...]
    nextProt Lacks the catalytic site and may interfere with the pro-apoptotic activity of the complex.
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
CASP8 BioGRID RIPK1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Co-localization; Reconstituted Complex
CASP8 BioGRID TRIM67 GeneID BioGRID Affinity Capture-MS
CASP8 BioGRID FADD GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-fractionation; Co-purification; Reconstituted Complex; Two-hybrid
CASP8 BioGRID ZBP1 GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID TRAF6 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; FRET
CASP8 BioGRID COMMD8 GeneID BioGRID Co-fractionation
CASP8 BioGRID IRF3 GeneID BioGRID Co-fractionation
CASP8 BioGRID IKBKB GeneID BioGRID Affinity Capture-Western; Co-fractionation
CASP8 BioGRID DDB2 GeneID BioGRID Co-fractionation
CASP8 BioGRID FAS GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-purification; Proximity Label-MS
CASP8 BioGRID TRIM28 GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID CFLAR GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity; Reconstituted Complex; Two-hybrid
CASP8 BioGRID USP27X GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID ANKRD13A GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID CYLD GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID CASP10 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Co-purification
CASP8 BioGRID PYCARD GeneID BioGRID Affinity Capture-Western; Co-localization
CASP8 BioGRID NR1H4 GeneID BioGRID Reconstituted Complex
CASP8 BioGRID TNFRSF10A GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity; Co-localization
CASP8 BioGRID TNFRSF10B GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity; Co-purification
CASP8 BioGRID TNF GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
CASP8 BioGRID SKP2 GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID IL1B GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
CASP8 BioGRID TICAM1 GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID OGT GeneID BioGRID Reconstituted Complex
CASP8 BioGRID GSDMD GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID PML GeneID BioGRID Affinity Capture-Western; Co-localization
CASP8 BioGRID RNF31 GeneID BioGRID Biochemical Activity
CASP8 BioGRID TNFSF10 GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID SRC GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
CASP8 BioGRID TRADD GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
CASP8 BioGRID ZNF707 GeneID BioGRID Two-hybrid
CASP8 BioGRID CCNL1 GeneID BioGRID Two-hybrid
CASP8 BioGRID BRD1 GeneID BioGRID Two-hybrid
CASP8 BioGRID AP1M1 GeneID BioGRID Two-hybrid
CASP8 BioGRID NLRP3 GeneID BioGRID Co-localization
CASP8 BioGRID GMEB1 GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID MAP1LC3B GeneID BioGRID Affinity Capture-Western; Two-hybrid
CASP8 BioGRID PLEKHA4 GeneID BioGRID Affinity Capture-MS
CASP8 BioGRID SQSTM1 GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID Trp53inp2 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
CASP8 BioGRID MAPT GeneID BioGRID Biochemical Activity
CASP8 BioGRID DYNC1LI2 GeneID BioGRID Proximity Label-MS
CASP8 BioGRID DYNC1LI1 GeneID BioGRID Proximity Label-MS
CASP8 BioGRID NOL3 GeneID BioGRID Affinity Capture-Western; Phenotypic Suppression
CASP8 BioGRID RIPK3 GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID BECN1 GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID TRAF2 GeneID BioGRID Affinity Capture-Western; Co-localization
CASP8 BioGRID MYC GeneID BioGRID Affinity Capture-MS
CASP8 BioGRID PIK3C3 GeneID BioGRID Biochemical Activity; Co-localization
CASP8 BioGRID CUL3 GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID HIP1 GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID TNFAIP3 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
CASP8 BioGRID PPP2CA GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID FAF1 GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID MAPK14 GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID SERPINB9 GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID OPTN GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID VHL GeneID BioGRID Negative Genetic
CASP8 BioGRID BIRC3 GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID BIRC2 GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID TLR3 GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID MTOR GeneID BioGRID Negative Genetic
CASP8 BioGRID CHEK1 GeneID BioGRID Negative Genetic
CASP8 BioGRID CDKN1B GeneID BioGRID Negative Genetic
CASP8 BioGRID CDK9 GeneID BioGRID Negative Genetic
CASP8 BioGRID NLRC4 GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID RYBP GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID BLM GeneID BioGRID Affinity Capture-MS
CASP8 BioGRID Vangl1 GeneID BioGRID Affinity Capture-MS
CASP8 BioGRID Ppp2r1a GeneID BioGRID Affinity Capture-MS
CASP8 BioGRID MLKL GeneID BioGRID Affinity Capture-MS
CASP8 BioGRID GMNN GeneID BioGRID Affinity Capture-MS
CASP8 BioGRID ATP1A3 GeneID BioGRID Two-hybrid
CASP8 BioGRID ST14 GeneID BioGRID Two-hybrid
CASP8 BioGRID SOX2 GeneID BioGRID Two-hybrid
CASP8 BioGRID QDPR GeneID BioGRID Two-hybrid
CASP8 BioGRID SERPINB5 GeneID BioGRID Two-hybrid
CASP8 BioGRID YBX1 GeneID BioGRID Two-hybrid
CASP8 BioGRID SCGB2A2 GeneID BioGRID Two-hybrid
CASP8 BioGRID IL13RA2 GeneID BioGRID Two-hybrid
CASP8 BioGRID CDH13 GeneID BioGRID Two-hybrid
CASP8 BioGRID BAP1 GeneID BioGRID Two-hybrid
CASP8 BioGRID CNBP GeneID BioGRID Two-hybrid
CASP8 BioGRID UMPS GeneID BioGRID Two-hybrid
CASP8 BioGRID BLID GeneID BioGRID Two-hybrid
CASP8 BioGRID KLK9 GeneID BioGRID Two-hybrid
CASP8 BioGRID AGR3 GeneID BioGRID Two-hybrid
CASP8 BioGRID EPSTI1 GeneID BioGRID Two-hybrid
CASP8 BioGRID PRDM14 GeneID BioGRID Two-hybrid
CASP8 BioGRID S100A14 GeneID BioGRID Two-hybrid
CASP8 BioGRID BEX1 GeneID BioGRID Two-hybrid
CASP8 BioGRID NSD3 GeneID BioGRID Two-hybrid
CASP8 BioGRID ERRFI1 GeneID BioGRID Two-hybrid
CASP8 BioGRID ANGPTL4 GeneID BioGRID Two-hybrid
CASP8 BioGRID PSMC3IP GeneID BioGRID Two-hybrid
CASP8 BioGRID PRSS50 GeneID BioGRID Two-hybrid
CASP8 BioGRID ATAD2 GeneID BioGRID Two-hybrid
CASP8 BioGRID LYPD3 GeneID BioGRID Two-hybrid
CASP8 BioGRID HBP1 GeneID BioGRID Two-hybrid
CASP8 BioGRID GLCE GeneID BioGRID Two-hybrid
CASP8 BioGRID KLK5 GeneID BioGRID Two-hybrid
CASP8 BioGRID CASC3 GeneID BioGRID Two-hybrid
CASP8 BioGRID VPS45 GeneID BioGRID Two-hybrid
CASP8 BioGRID IL24 GeneID BioGRID Two-hybrid
CASP8 BioGRID BCL2L10 GeneID BioGRID Two-hybrid
CASP8 BioGRID GREB1 GeneID BioGRID Two-hybrid
CASP8 BioGRID Sqstm1 GeneID BioGRID Biochemical Activity
CASP8 BioGRID UBC GeneID BioGRID Reconstituted Complex
CASP8 BioGRID ATG4D GeneID BioGRID Biochemical Activity
CASP8 BioGRID PARP1 GeneID BioGRID Biochemical Activity
CASP8 BioGRID BCL2 GeneID BioGRID Affinity Capture-Western; Phenotypic Suppression; Two-hybrid
CASP8 BioGRID XIAP GeneID BioGRID Affinity Capture-Western; Phenotypic Suppression
CASP8 BioGRID RNF34 GeneID BioGRID Affinity Capture-Western; Two-hybrid
CASP8 BioGRID BAX GeneID BioGRID Co-fractionation
CASP8 BioGRID ced-4 GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID ERLIN2 GeneID BioGRID Affinity Capture-MS
CASP8 BioGRID PRDX6 GeneID BioGRID Affinity Capture-Western; PCA; Reconstituted Complex
CASP8 BioGRID CRYAB GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID HECTD3 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
CASP8 BioGRID GZMB GeneID BioGRID Biochemical Activity
CASP8 BioGRID PLA2G4B GeneID BioGRID Biochemical Activity
CASP8 BioGRID RB1 GeneID BioGRID Biochemical Activity
CASP8 BioGRID PLIN4 GeneID BioGRID Two-hybrid
CASP8 BioGRID BCAP31 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Co-fractionation; Reconstituted Complex
CASP8 BioGRID PDIA6 GeneID BioGRID Two-hybrid
CASP8 BioGRID SNRPD3 GeneID BioGRID Two-hybrid
CASP8 BioGRID PRKCI GeneID BioGRID Two-hybrid
CASP8 BioGRID PARK7 GeneID BioGRID Reconstituted Complex
CASP8 BioGRID LRRK2 GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID CARD11 GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID FIS1 GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID CASP3 GeneID BioGRID Biochemical Activity
CASP8 BioGRID FASLG GeneID BioGRID Affinity Capture-Western; Co-purification
CASP8 BioGRID TOPORS GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID TP53 GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID CASP8 GeneID BioGRID Biochemical Activity; Co-crystal Structure; Two-hybrid
CASP8 BioGRID MAPK1 GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID BIRC6 GeneID BioGRID Biochemical Activity
CASP8 BioGRID BFAR GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID CLIP3 GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID COPS6 GeneID BioGRID Biochemical Activity
CASP8 BioGRID CEBPB GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID SORBS1 GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID MAP1LC3A GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID USP2 GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID TSC22D3 GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID KHDRBS1 GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID PTEN GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
CASP8 BioGRID RALGDS GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID HDAC7 GeneID BioGRID Biochemical Activity
CASP8 BioGRID AIF1 GeneID BioGRID Phenotypic Suppression
CASP8 BioGRID MCA1 GeneID BioGRID Phenotypic Suppression
CASP8 Protein BFAR GeneID HPRD
CASP8 Protein GMEB1 GeneID HPRD
CASP8 Protein PIAS1 GeneID HPRD
CASP8 Protein TOPORS GeneID HPRD
CASP8 Protein DEDD2 GeneID HPRD
CASP8 Protein STK24 GeneID HPRD
CASP8 Protein PARP2 GeneID HPRD
CASP8 Protein RYBP GeneID HPRD
CASP8 Protein USO1 GeneID HPRD
CASP8 Protein CHD3 GeneID HPRD
CASP8 Protein RALBP1 GeneID HPRD
CASP8 Protein CDK11B GeneID HPRD
CASP8 Protein CASP8AP2 GeneID HPRD
CASP8 Protein DEDD GeneID HPRD
CASP8 Protein NOD1 GeneID HPRD
CASP8 Protein CASP14 GeneID HPRD
CASP8 Protein NOL3 GeneID HPRD
CASP8 Protein MAP3K14 GeneID HPRD
CASP8 Protein FAF1 GeneID HPRD
CASP8 Protein NR1H4 GeneID HPRD
CASP8 Protein TNFRSF10B GeneID HPRD
CASP8 Protein TNFRSF10A GeneID HPRD
CASP8 Protein CFLAR GeneID HPRD
CASP8 Protein RIPK2 GeneID HPRD
CASP8 Protein CRADD GeneID HPRD
CASP8 Protein RIPK1 GeneID HPRD
CASP8 Protein PEA15 GeneID HPRD
CASP8 Protein IKBKB GeneID HPRD
CASP8 Protein PICALM GeneID HPRD
CASP8 Protein PRKN GeneID HPRD
CASP8 Protein FADD GeneID HPRD
CASP8 Protein ILK GeneID HPRD
CASP8 Protein APAF1 GeneID HPRD
CASP8 Protein BID GeneID HPRD
CASP8 Protein SUMO1 GeneID HPRD
CASP8 Protein TRAF2 GeneID HPRD
CASP8 Protein MAPK3 GeneID HPRD
CASP8 Protein HIP1 GeneID HPRD
CASP8 Protein CASP8 GeneID HPRD
CASP8 Protein CASP10 GeneID HPRD
CASP8 Protein TRAF1 GeneID HPRD
CASP8 Protein CASP6 GeneID HPRD
CASP8 Protein PLEC GeneID HPRD
CASP8 Protein CDKN1B GeneID HPRD
CASP8 Protein PSEN2 GeneID HPRD
CASP8 Protein CHUK GeneID HPRD
CASP8 Protein CASP3 GeneID HPRD
CASP8 Protein SRF GeneID HPRD
CASP8 Protein BCL2L1 GeneID HPRD
CASP8 Protein AR GeneID HPRD
CASP8 Protein BCAP31 GeneID HPRD
CASP8 Protein EDA2R GeneID HPRD
CASP8 Protein IKBKG GeneID HPRD
CASP8 Protein VIM GeneID HPRD
CASP8 Protein CDH1 GeneID HPRD
CASP8 Protein TFCP2 GeneID HPRD
CASP8 Protein RB1 GeneID HPRD
CASP8 Protein PRKCZ GeneID HPRD
CASP8 Protein MAPK1 GeneID HPRD
CASP8 Protein EIF2AK2 GeneID HPRD
CASP8 Protein MAPT GeneID HPRD
CASP8 Protein BCL2 GeneID HPRD
CASP8 Protein KRT18 GeneID HPRD
CASP8 Protein GRIA1 GeneID HPRD
CASP8 Protein FYN GeneID HPRD
CASP8 Protein FAS GeneID HPRD
CASP8 Protein PCYT1A GeneID HPRD
CASP8 Protein CDK11A GeneID HPRD
CASP8 Protein CTNNB1 GeneID HPRD
CASP8 Protein APP GeneID HPRD
CASP8 Protein PSEN1 GeneID HPRD
CASP8 BioGRID DEDD GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
CASP8 BioGRID CASP14 GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID CASP9 GeneID BioGRID Biochemical Activity; Phenotypic Suppression
CASP8 BioGRID CASP7 GeneID BioGRID Biochemical Activity
CASP8 BioGRID CASP6 GeneID BioGRID Biochemical Activity
CASP8 BioGRID CASP4 GeneID BioGRID Biochemical Activity
CASP8 BioGRID CASP2 GeneID BioGRID Biochemical Activity
CASP8 BioGRID CASP1 GeneID BioGRID Biochemical Activity
CASP8 BioGRID BID GeneID BioGRID Biochemical Activity; Co-purification
CASP8 BioGRID BCL2L1 GeneID BioGRID Phenotypic Suppression
CASP8 BioGRID DEDD2 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
CASP8 BioGRID CASP8AP2 GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID MAP3K14 GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID CHUK GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID APAF1 GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID IFT57 GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID NOD1 GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID PEA15 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
CASP8 BioGRID TRAF1 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
CASP8 BioGRID VIM GeneID BioGRID Two-hybrid
CASP8 BioGRID TFCP2 GeneID BioGRID Two-hybrid
CASP8 BioGRID CHD3 GeneID BioGRID Two-hybrid
CASP8 BioGRID RALBP1 GeneID BioGRID Affinity Capture-Western
CASP8 BioGRID EZR GeneID BioGRID Co-purification
CASP8 BioGRID TNFRSF1A GeneID BioGRID Co-purification
CASP8 BioGRID MAPK8 GeneID BioGRID Co-purification
CASP8 BioGRID MSN GeneID BioGRID Co-purification
CASP8 BioGRID ARHGDIA GeneID BioGRID Co-purification
CASP8 BioGRID RHOA GeneID BioGRID Co-purification
CASP8 Protein SUMO1 GeneID BIND CASP8 (caspase-8) interacts with SUMO1.
CASP8 Protein PIAS1 GeneID BIND CASP8 (caspase-8) interacts with PIAS-1.
CASP8 Protein FADD GeneID BIND CASP8 (caspase-8) interacts with FADD.
CASP8 Protein RB1 GeneID BIND CASP8 (caspase-8) cleaves RB-1 (hRB) into the p68 form and to a lesser extent the p61 form.
CASP8 None None None BIND MRIT-alpha-1 interacts with FLICE. This interaction was modelled on a demonstrated interaction between human MRIT-alpha-1 and FLICE from an unspecified species.
CASP8 None None None BIND ARC interacts with procaspase-8.
CASP8 None None None BIND MRIT-beta-1 interacts with FLICE. This interaction was modelled on a demonstrated interaction between human MRIT-beta-1 and FLICE from an unspecified species.
CASP8 None None None BIND caspase-8 interacts with FADD.
CASP8 Protein AR GeneID BIND Androgen Receptor interacts with caspase 8.
CASP8 Protein ATN1 GeneID BIND Atrophin-1 interacts with caspase 8.
CASP8 Protein HTT GeneID BIND Htt interacts with caspase 8.
StringDB
A B experiments database textmining combined score hadb nhadb
CASP8 HIST2H2AA3 0 0 166 165 1 1
CASP8 HDAC4 0 0 208 208 1 2
CASP8 IL21 0 0 45 299 1 1
CASP8 LTB 0 0 122 199 1 1
CASP8 BCL3 0 0 47 179 1 1
CASP8 HSP90AA1 0 0 519 544 1 2
CASP8 PSEN1 213 0 267 411 1 2
CASP8 ATF2 0 0 154 155 1 1
CASP8 TP73 0 0 369 449 1 2
CASP8 CRP 0 0 233 246 1 2
CASP8 RFFL 270 0 54 279 1 1
CASP8 SOX2 76 0 247 274 1 2
CASP8 SP100 0 0 107 196 1 1
CASP8 ACSBG1 0 0 66 161 1 1
CASP8 EPHA7 0 0 74 161 1 1
CASP8 HIST2H2AA 0 0 166 165 1 1
CASP8 SELL 0 0 204 250 1 1
CASP8 ARHGDIA 287 0 112 364 1 1
CASP8 SLA2 0 0 290 310 1 1
CASP8 NLRX1 0 0 453 461 1 2
CASP8 SELP 0 0 150 197 1 1
CASP8 ATG13 0 0 261 289 1 2
CASP8 MSN 287 0 113 385 1 1
CASP8 CRYZ 0 0 117 150 1 1
CASP8 ANXA4 0 0 112 504 1 1
CASP8 BNIP3 0 0 455 519 1 2
CASP8 SQSTM1 753 0 963 991 1 2
CASP8 MICB 0 0 147 168 1 1
CASP8 MMP9 0 0 519 544 1 2
CASP8 MAPK3 270 900 746 980 1 2
CASP8 THY1 0 0 212 212 1 1
CASP8 BID 678 900 806 994 1 2
CASP8 IFNAR2 0 0 189 207 1 1
CASP8 GSN 0 0 444 456 1 1
CASP8 AR 270 900 614 972 1 2
CASP8 CDKN1A 0 0 561 569 1 2
CASP8 EBAG9 0 0 81 177 1 1
CASP8 SPP1 270 0 265 440 1 2
CASP8 ALS2CR12 0 0 450 450 1 1
CASP8 ATG9A 0 0 95 179 1 2
CASP8 BAX 270 0 680 796 1 2
CASP8 TIMP1 0 0 341 345 1 1
CASP8 STX1A 0 0 145 168 1 1
CASP8 AURKA 0 0 211 228 1 2
CASP8 TNNI3 0 0 153 152 1 1
CASP8 XKR8 0 0 158 196 1 1
CASP8 PTPRC 0 0 390 441 1 1
CASP8 BCL2L12 0 0 170 169 1 1
CASP8 CXCR1 0 0 167 188 1 1
CASP8 ITGAV 0 900 152 911 1 1
CASP8 SMDT1 0 0 274 307 1 1
CASP8 BCL10 270 800 985 998 1 1
CASP8 IGFBP2 0 0 181 181 1 1
CASP8 CCNB2 0 0 155 165 1 1
CASP8 ICAM1 0 0 401 440 1 2
CASP8 ASAP3 0 0 0 163 1 1
CASP8 FYN 213 0 260 409 1 1
CASP8 GRB2 0 0 278 282 1 1
CASP8 GTF2F1 0 0 0 161 1 1
CASP8 NFKBIE 0 0 209 276 1 1
CASP8 CLEC6A 0 0 184 183 1 1
CASP8 ASIP 0 0 0 250 1 1
CASP8 JAG1 0 0 181 194 1 1
CASP8 PARP14 0 0 90 211 1 1
CASP8 SOD1 0 0 415 452 1 2
CASP8 LTA 0 0 261 446 1 1
CASP8 CDC25C 0 0 469 515 1 2
CASP8 TBL1X 0 0 138 158 1 1
CASP8 IL36RN 0 0 90 198 1 1
CASP8 IL7R 0 0 183 242 1 1
CASP8 SMC3 0 0 90 150 1 1
CASP8 BMI1 0 0 180 179 1 1
CASP8 LSP1 0 0 458 497 1 1
CASP8 EIF2AK2 213 0 235 449 1 2
CASP8 MFN1 0 0 215 245 1 2
CASP8 NFATC3 0 0 150 186 1 1
CASP8 COL3A1 0 900 86 904 1 1
CASP8 KRT8 0 0 156 174 1 1
CASP8 TNFRSF13C 0 0 203 203 1 1
CASP8 RUNX3 0 0 210 236 1 1
CASP8 TRIM38 0 0 74 163 1 1
CASP8 TOX3 0 0 466 465 1 1
CASP8 DNTT 0 0 681 695 1 1
CASP8 CCNA2 0 0 518 528 1 1
CASP8 NOS1 0 0 486 485 1 1
CASP8 HIC1 0 0 324 334 1 1
CASP8 COL18A1 0 0 193 208 1 1
CASP8 AIF1 0 0 242 254 1 2
CASP8 ERBB4 0 0 210 225 1 1
CASP8 JAK3 0 0 181 217 1 1
CASP8 PIK3CG 0 0 210 281 1 1
CASP8 BOK 0 0 391 492 1 1
CASP8 GZMA 0 0 264 295 1 1
CASP8 CDH17 0 0 270 270 1 1
CASP8 SERPINB2 0 0 123 176 1 1
CASP8 ITGAL 0 0 124 185 1 1
CASP8 ENSG00000173366 0 0 392 433 1 1
CASP8 CYP19A1 0 0 254 254 1 2
CASP8 JUN 0 0 682 709 1 2
CASP8 DAPK1 0 0 460 459 1 2
CASP8 TYK2 0 0 166 202 1 1
CASP8 CYP1B1 0 0 435 435 1 1
CASP8 MC1R 0 0 150 182 1 1
CASP8 HSPA4 0 0 522 589 1 1
CASP8 IRF2 0 0 147 183 1 1
CASP8 CTSH 0 0 117 166 1 1
CASP8 PLAUR 0 0 212 244 1 1
CASP8 PIK3R1 0 0 961 977 1 1
CASP8 CLTC 0 900 73 903 1 1
CASP8 DICER1 0 0 280 409 1 1
CASP8 ISG20 0 0 111 175 1 1
CASP8 DDX1 0 0 112 166 1 1
CASP8 CCR2 0 0 232 282 1 2
CASP8 COL4A4 0 900 0 900 1 1
CASP8 HSPB3 0 0 457 466 1 1
CASP8 XPO5 0 0 108 163 1 1
CASP8 CYP2E1 0 0 298 303 1 2
CASP8 PDCD4 0 0 234 234 1 2
CASP8 HSP90B1 0 0 323 347 1 1
CASP8 CBR1 0 0 51 154 1 1
CASP8 ACHE 0 0 180 179 1 2
CASP8 TEK 0 0 171 171 1 1
CASP8 IER3 0 0 155 154 1 1
CASP8 CXCL9 0 0 211 228 1 1
CASP8 PPARA 0 0 293 307 1 2
CASP8 TRAF6 816 0 972 995 1 2
CASP8 SESN3 0 0 122 156 1 1
CASP8 IL18BP 0 0 151 150 1 1
CASP8 APPL2 0 0 0 182 1 1
CASP8 CXCL11 0 0 176 187 1 1
CASP8 CYCS 0 0 878 907 1 2
CASP8 GADD45B 0 0 294 294 1 1
CASP8 PAWR 0 0 380 380 1 1
CASP8 EGF 0 0 502 511 1 2
CASP8 PRTN3 0 0 217 217 1 1
CASP8 PLAU 0 0 252 288 1 1
CASP8 PCSK1 0 0 651 682 1 1
CASP8 BFAR 270 0 445 614 1 1
CASP8 PELI1 0 0 139 171 1 1
CASP8 XRCC1 0 0 235 235 1 1
CASP8 PTK2 0 0 769 771 1 2
CASP8 MAPK8 287 0 609 720 1 2
CASP8 MUT 0 0 151 151 1 1
CASP8 BRAF 0 0 158 178 1 2
CASP8 GOLGA3 0 0 166 165 1 1
CASP8 MAP2K4 0 0 385 409 1 1
CASP8 VPS33A 270 0 0 270 1 1
CASP8 API5 0 0 150 215 1 1
CASP8 ARHGDIB 0 0 96 157 1 1
CASP8 CDK11A 213 0 67 234 1 1
CASP8 IL1F10 0 0 107 213 1 1
CASP8 GPX4 0 0 268 313 1 2
CASP8 DIABLO 0 0 824 865 1 2
CASP8 SPATA2 0 0 164 163 1 1
CASP8 SESN2 0 0 204 204 1 2
CASP8 COL4A1 0 900 60 901 1 1
CASP8 P2RX7 0 0 261 294 1 2
CASP8 CCR1 0 0 138 192 1 1
CASP8 SRPK1 0 0 156 155 1 1
CASP8 CHKA 0 0 170 169 1 1
CASP8 GATA1 0 0 157 156 1 1
CASP8 MAP3K11 0 0 202 220 1 1
CASP8 FAM26F 0 0 72 164 1 1
CASP8 ATG16L2 0 0 127 150 1 2
CASP8 MAF 0 0 228 227 1 1
CASP8 GBP1 0 0 129 163 1 1
CASP8 AVP 0 0 117 164 1 1
CASP8 ACTR1B 0 0 0 155 1 1
CASP8 CRYGC 0 0 294 294 1 1
CASP8 ALK 0 0 240 257 1 2
CASP8 ROCK2 0 0 103 162 1 1
CASP8 MRPS7 0 0 158 183 1 1
CASP8 TRADD 875 900 989 999 1 1
CASP8 WNT1 0 0 124 163 1 2
CASP8 CYP3A4 0 0 155 154 1 1
CASP8 AGER 0 0 195 195 1 2
CASP8 ACTC1 0 0 62 204 1 1
CASP8 SIRT6 0 0 213 213 1 2
CASP8 AMD1 0 0 97 159 1 1
CASP8 HSPA14 0 0 48 161 1 1
CASP8 BUB1B 0 0 181 181 1 1
CASP8 BCL2L13 0 0 190 190 1 2
CASP8 CDH1 213 0 588 661 1 2
CASP8 IDH1 0 0 194 224 1 1
CASP8 CD33 0 0 142 167 1 1
CASP8 PRKCZ 213 0 259 405 1 1
CASP8 MB21D1 0 0 251 279 1 1
CASP8 LEF1 0 0 155 162 1 1
CASP8 TECR 0 0 165 165 1 1
CASP8 PDGFRB 0 0 242 241 1 2
CASP8 EP300 0 0 328 328 1 2
CASP8 CDK5 0 0 216 221 1 2
CASP8 IL4 0 0 396 404 1 1
CASP8 SMAD3 0 0 293 293 1 2
CASP8 PLS3 0 0 81 155 1 1
CASP8 ANXA8 0 0 603 603 1 1
CASP8 BIRC3 486 900 744 990 1 1
CASP8 PTBP2 0 900 0 900 1 1
CASP8 ERO1L 0 0 244 243 1 1
CASP8 ROCK1 0 0 294 325 1 2
CASP8 NEK10 0 0 210 210 1 1
CASP8 TP53AIP1 0 0 210 210 1 1
CASP8 IDO1 0 0 194 212 1 1
CASP8 CARD17 0 0 139 497 1 1
CASP8 EIF4A1 0 900 125 910 1 1
CASP8 SNAI2 0 0 243 258 1 1
CASP8 OTULIN 0 0 246 247 1 1
CASP8 YAF2 0 0 92 203 1 1
CASP8 CCL2 0 0 459 470 1 2
CASP8 ALB 0 0 562 638 1 2
CASP8 SNX32 0 0 72 171 1 1
CASP8 CD68 0 0 264 282 1 2
CASP8 ANXA3 0 0 90 492 1 1
CASP8 CASP7 488 900 856 959 1 1
CASP8 CUL1 0 0 173 173 1 1
CASP8 ELAVL1 0 0 181 198 1 2
CASP8 MICA 0 0 170 169 1 1
CASP8 AATF 0 0 134 193 1 1
CASP8 MMP15 0 0 66 210 1 1
CASP8 CDIP1 0 0 161 161 1 1
CASP8 MYH6 0 0 122 150 1 1
CASP8 GCLM 0 0 134 171 1 1
CASP8 EIF2AK4 0 0 181 181 1 2
CASP8 GDNF 0 0 193 193 1 2
CASP8 POTEG 0 0 0 155 1 1
CASP8 IFNA2 0 0 163 163 1 1
CASP8 CD300C 0 0 212 212 1 1
CASP8 HBEGF 0 0 161 161 1 1
CASP8 JAK2 0 0 401 431 1 2
CASP8 NLRC5 0 0 143 205 1 1
CASP8 CDH2 0 0 321 321 1 1
CASP8 HDAC6 0 0 339 341 1 2
CASP8 APAF1 270 0 854 945 1 2
CASP8 ORAOV1 0 0 87 153 1 1
CASP8 CLU 0 0 209 209 1 2
CASP8 HUWE1 0 0 134 181 1 1
CASP8 BRD4 0 0 166 165 1 2
CASP8 ACTL7B 0 0 0 155 1 1
CASP8 NR4A1 0 0 265 265 1 2
CASP8 IRAK1 0 0 405 468 1 1
CASP8 PSTPIP2 0 0 208 265 1 1
CASP8 RAF1 151 0 348 436 1 2
CASP8 CARD9 270 800 832 980 1 1
CASP8 RBL1 0 0 154 191 1 1
CASP8 MAP3K7 0 0 402 427 1 2
CASP8 HDAC2 0 0 256 256 1 1
CASP8 EDA 0 0 94 256 1 1
CASP8 ZBP1 0 0 370 430 1 1
CASP8 MAP1A 0 0 207 213 1 2
CASP8 TNFRSF11B 0 0 395 404 1 1
CASP8 NFKBIZ 0 0 107 216 1 1
CASP8 MDM2 0 0 561 770 1 2
CASP8 LCN2 0 0 138 179 1 1
CASP8 TP53 270 800 804 977 1 2
CASP8 ALOX15 0 0 165 165 1 1
CASP8 TGM2 0 0 167 185 1 2
CASP8 LRIG1 0 0 64 154 1 1
CASP8 FGFR3 0 0 175 175 1 1
CASP8 LAMP1 0 0 280 290 1 2
CASP8 NEDD8 0 0 142 175 1 2
CASP8 SLC2A1 0 0 212 212 1 2
CASP8 MAP3K13 0 0 458 458 1 1
CASP8 ATP2C1 0 0 166 207 1 1
CASP8 EGFR 0 0 593 605 1 2
CASP8 CFLAR 981 900 990 998 1 2
CASP8 HTT 0 0 310 340 1 2
CASP8 TNFRSF4 0 0 193 193 1 1
CASP8 RB1CC1 0 0 252 252 1 2
CASP8 BRCA1 0 0 460 471 1 2
CASP8 STK11 0 0 301 301 1 2
CASP8 GTF3C3 0 0 383 382 1 1
CASP8 MAP3K8 0 0 181 218 1 1
CASP8 OPA1 0 0 150 182 1 2
CASP8 TNFRSF12A 0 0 325 325 1 1
CASP8 ST20 0 0 0 200 1 1
CASP8 CTSE 0 0 134 201 1 1
CASP8 GPR78 0 0 150 169 1 1
CASP8 CASP10 880 900 989 990 1 1
CASP8 MOAP1 0 0 166 188 1 1
CASP8 ACTA1 0 0 108 248 1 1
CASP8 ZNF501 0 0 314 324 1 1
CASP8 MEFV 0 0 755 785 1 1
CASP8 RICTOR 0 0 181 186 1 2
CASP8 P4HB 0 0 181 289 1 2
CASP8 GPX7 0 0 73 326 1 1
CASP8 TMBIM6 0 0 207 212 1 1
CASP8 CEACAM5 0 0 181 181 1 1
CASP8 TOP1 0 0 408 446 1 1
CASP8 TUBA3D 0 0 52 161 1 1
CASP8 IL2RA 0 0 170 178 1 1
CASP8 FCGR1B 0 0 134 152 1 1
CASP8 CBLB 0 0 60 160 1 1
CASP8 IL15 0 0 310 342 1 1
CASP8 RNF125 0 0 112 172 1 1
CASP8 RALGDS 270 0 91 308 1 1
CASP8 LGMN 0 0 136 169 1 1
CASP8 PARK2 213 0 234 379 1 1
CASP8 NR0B2 0 0 141 164 1 1
CASP8 IFNA1 0 0 468 468 1 1
CASP8 WNT5A 0 0 134 190 1 2
CASP8 ILK 270 0 218 435 1 1
CASP8 PPARGC1A 0 0 233 232 1 2
CASP8 ADAM10 0 0 146 169 1 1
CASP8 PML 0 0 160 159 1 2
CASP8 FGFR2 0 0 346 345 1 1
CASP8 CYP1A1 0 0 243 242 1 2
CASP8 GAPDH 0 0 682 689 1 2
CASP8 CD83 0 0 150 177 1 1
CASP8 CENPV 0 0 154 153 1 1
CASP8 TNFSF15 0 0 295 307 1 1
CASP8 ABL1 0 0 341 356 1 1
CASP8 HIST4H4 0 0 220 220 1 1
CASP8 PTBP1 0 900 113 907 1 2
CASP8 CX3CL1 0 0 180 180 1 1
CASP8 TNFAIP8L1 0 0 163 274 1 1
CASP8 MAP2K7 0 900 517 950 1 1
CASP8 CLDN15 0 0 134 154 1 1
CASP8 TRIM25 0 600 184 668 1 1
CASP8 MMP20 0 0 45 192 1 1
CASP8 TLR10 0 0 146 372 1 1
CASP8 ZAP70 0 0 245 297 1 1
CASP8 ITGA4 0 0 134 193 1 1
CASP8 STAT4 0 0 96 260 1 1
CASP8 CASP6 675 900 802 973 1 1
CASP8 EVPL 0 0 92 174 1 1
CASP8 CD7 0 0 123 169 1 1
CASP8 NFKB1 0 900 406 946 1 2
CASP8 CDH13 59 0 218 232 1 1
CASP8 RELA 0 900 563 956 1 2
CASP8 TPCN1 0 0 134 152 1 1
CASP8 MAP1LC3B2 0 0 0 157 1 1
CASP8 SLC25A6 0 0 134 245 1 1
CASP8 SIRT2 0 0 283 282 1 2
CASP8 SLC4A7 0 0 283 282 1 1
CASP8 C5AR1 0 0 134 177 1 1
CASP8 SDHB 0 0 183 183 1 1
CASP8 NFE2 0 0 82 156 1 1
CASP8 PPID 0 0 180 193 1 1
CASP8 CREBBP 0 0 261 265 1 1
CASP8 DGCR8 0 0 120 154 1 1
CASP8 KHDRBS1 270 0 155 427 1 1
CASP8 APC 0 0 151 150 1 1
CASP8 GZMM 0 0 202 202 1 1
CASP8 HIST2H2AC 0 0 164 163 1 1
CASP8 USP9X 0 0 234 257 1 1
CASP8 GSDMD 0 0 622 674 1 2
CASP8 CREB1 0 0 370 373 1 2
CASP8 TMEM219 270 0 130 411 1 1
CASP8 ACAN 0 0 141 159 1 1
CASP8 PIK3C3 270 0 392 548 1 2
CASP8 CTRL 0 0 373 373 1 2
CASP8 DCXR 0 0 358 358 1 1
CASP8 ENDOG 0 0 653 692 1 1
CASP8 STAT1 0 0 469 495 1 2
CASP8 BCL2L2-PABPN1 0 0 601 672 1 1
CASP8 GZMB 270 800 505 921 1 1
CASP8 TFPI2 0 0 113 212 1 1
CASP8 PLEK 0 0 188 225 1 1
CASP8 OCLN 0 0 260 260 1 1
CASP8 CYR61 0 0 140 159 1 1
CASP8 CXCR4 0 0 340 369 1 2
CASP8 HIST1H4F 0 0 218 218 1 1
CASP8 MMP1 0 0 267 284 1 1
CASP8 MTOR 131 0 517 579 1 2
CASP8 RAD51 0 0 213 214 1 2
CASP8 E2F2 0 0 155 183 1 1
CASP8 ANXA11 0 0 90 395 1 1
CASP8 PSMC6 0 0 218 218 1 1
CASP8 ADAR 0 0 153 152 1 1
CASP8 CTNNB1 213 0 556 663 1 2
CASP8 MSH6 0 0 171 171 1 1
CASP8 HRAS 0 0 518 556 1 2
CASP8 RBM5 0 0 104 165 1 1
CASP8 APP 200 900 342 942 1 2
CASP8 MFN2 0 0 232 261 1 2
CASP8 EGR1 0 0 261 272 1 2
CASP8 WNT2B 0 0 66 173 1 1
CASP8 SP140L 0 0 82 150 1 1
CASP8 IKBKE 0 0 175 309 1 1
CASP8 POTEM 0 0 0 155 1 1
CASP8 BAG3 0 0 203 217 1 2
CASP8 NEDD4 0 0 137 169 1 2
CASP8 RAB5A 0 0 355 371 1 2
CASP8 CXCL8 0 0 518 538 1 2
CASP8 KLK3 0 0 260 260 1 1
CASP8 ASAP1 0 0 62 182 1 1
CASP8 NFKBID 0 0 94 179 1 1
CASP8 CTSL 0 0 262 275 1 2
CASP8 IL6R 0 0 202 243 1 1
CASP8 TRIB3 0 0 163 231 1 2
CASP8 ATG4D 270 0 305 500 1 2
CASP8 HYPK 0 0 67 184 1 1
CASP8 CXCL1 0 0 324 364 1 2
CASP8 IL33 0 0 283 283 1 2
CASP8 MMP14 0 0 181 204 1 1
CASP8 HSPA1B 0 0 74 270 1 1
CASP8 RGN 0 0 155 213 1 1
CASP8 TNFRSF21 0 0 470 481 1 1
CASP8 FIGF 0 0 113 150 1 1
CASP8 LIMK1 0 0 82 182 1 1
CASP8 IL1RL1 0 0 112 152 1 1
CASP8 DAXX 0 900 647 964 1 1
CASP8 AFP 0 0 701 708 1 2
CASP8 PGLYRP1 0 0 140 176 1 1
CASP8 TUBE1 0 0 57 174 1 1
CASP8 RPSA 0 0 232 248 1 1
CASP8 NQO1 0 0 282 282 1 2
CASP8 CCL11 0 0 141 159 1 1
CASP8 PSMB9 0 0 193 239 1 1
CASP8 FGF19 0 0 113 164 1 1
CASP8 BCAR1 0 0 145 163 1 1
CASP8 ALOX5 0 0 218 218 1 1
CASP8 NOTCH2 0 0 261 289 1 1
CASP8 PRKCQ 0 0 155 185 1 2
CASP8 ATG12 0 0 592 612 1 2
CASP8 CD5 0 0 170 212 1 1
CASP8 CD28 0 0 394 433 1 1
CASP8 TAF6 0 0 73 199 1 1
CASP8 PPIA 0 0 194 217 1 1
CASP8 NR2C2 0 0 140 157 1 1
CASP8 CXCL5 0 0 165 222 1 1
CASP8 SFN 0 0 218 233 1 2
CASP8 FABP4 0 0 140 176 1 1
CASP8 SOCS2 0 0 155 154 1 1
CASP8 CASP4 270 0 654 552 1 2
CASP8 ACTL9 0 0 0 155 1 1
CASP8 ERCC1 0 0 267 267 1 1
CASP8 XRCC5 0 0 200 200 1 1
CASP8 ITGAX 0 0 286 316 1 1
CASP8 SLC11A1 0 0 112 194 1 1
CASP8 WNT2 0 0 90 288 1 1
CASP8 RBL2 0 0 233 250 1 1
CASP8 S100A12 0 0 113 164 1 1
CASP8 KLF2 0 0 263 274 1 1
CASP8 HIST2H4A 0 0 218 218 1 1
CASP8 CUL3 835 0 885 980 1 2
CASP8 CHUK 270 900 821 987 1 1
CASP8 TSPO 0 0 122 158 1 1
CASP8 PLA2G4B 270 0 0 270 1 1
CASP8 STK24 213 0 48 218 1 1
CASP8 HCK 0 0 163 200 1 1
CASP8 DHFR 0 0 150 327 1 1
CASP8 SLC25A38 0 0 0 173 1 1
CASP8 CRYAB 270 0 44 285 1 2
CASP8 PHB2 0 0 134 152 1 1
CASP8 CSF1 0 0 282 297 1 1
CASP8 HDAC1 0 0 341 355 1 2
CASP8 FOS 0 0 427 440 1 2
CASP8 TWIST1 0 0 181 181 1 1
CASP8 YWHAZ 0 0 163 189 1 1
CASP8 RNF34 270 0 81 300 1 1
CASP8 CRKL 0 0 457 484 1 1
CASP8 COPS6 270 0 90 307 1 1
CASP8 PTPN11 0 0 233 233 1 1
CASP8 MLEC 0 0 0 161 1 1
CASP8 IRAK3 0 0 141 198 1 1
CASP8 CASP14 270 0 423 352 1 1
CASP8 NRAS 0 0 269 308 1 1
CASP8 DNM1 0 0 140 200 1 1
CASP8 E2F1 0 0 243 252 1 2
CASP8 HSPA5 160 0 562 673 1 2
CASP8 PICALM 213 0 0 213 1 1
CASP8 BTRC 0 0 214 214 1 1
CASP8 FOXO1 0 0 370 370 1 2
CASP8 SOD2 0 0 413 425 1 2
CASP8 IFNGR1 0 0 162 187 1 1
CASP8 CDK9 129 0 210 282 1 1
CASP8 GPX2 0 0 108 248 1 1
CASP8 CCL7 0 0 135 153 1 1
CASP8 OTUD7B 270 0 120 340 1 1
CASP8 SDC1 0 0 294 314 1 1
CASP8 WEE1 0 0 274 289 1 1
CASP8 IFT57 270 800 838 978 1 1
CASP8 ALDH1A1 0 0 134 152 1 1
CASP8 PEA15 486 0 469 715 1 1
CASP8 ANKRD45 0 0 0 152 1 1
CASP8 PMAIP1 0 0 682 701 1 2
CASP8 PIK3CB 0 0 151 181 1 1
CASP8 TLR2 0 0 469 507 1 2
CASP8 CERS6 0 0 216 233 1 1
CASP8 CDKN2B 0 0 322 356 1 1
CASP8 LRRK2 270 0 462 622 1 2
CASP8 TOLLIP 0 0 265 278 1 1
CASP8 MET 0 0 323 358 1 2
CASP8 TRAF3 0 0 508 539 1 2
CASP8 PHB 0 0 213 213 1 1
CASP8 PARP2 213 0 184 399 1 1
CASP8 CD86 0 0 323 338 1 1
CASP8 FKBP9 0 0 0 412 1 1
CASP8 SHARPIN 0 0 456 471 1 1
CASP8 NOD1 270 600 376 820 1 2
CASP8 PDIA3 0 0 243 328 1 1
CASP8 XBP1 0 0 459 475 1 2
CASP8 STAT2 0 0 241 263 1 1
CASP8 TP63 0 0 240 336 1 2
CASP8 SP3 0 0 193 205 1 1
CASP8 HIPK2 0 0 150 188 1 2
CASP8 ACTRT2 0 0 0 155 1 1
CASP8 TMEM63C 0 0 49 157 1 1
CASP8 PTPN1 0 0 214 214 1 1
CASP8 MT-ND1 0 0 66 210 1 1
CASP8 NLRP14 0 0 86 170 1 1
CASP8 WNT3A 0 0 122 179 1 2
CASP8 HTATIP2 0 0 165 168 1 1
CASP8 MAP2K6 0 0 170 188 1 1
CASP8 KSR1 0 0 145 164 1 1
CASP8 ATG5 0 0 917 965 1 2
CASP8 ITGB3 0 900 904 990 1 1
CASP8 BCL2L14 0 0 228 356 1 1
CASP8 TLR8 0 0 266 321 1 1
CASP8 BACE1 0 0 164 178 1 2
CASP8 TUBB 0 0 91 204 1 1
CASP8 ITGAM 0 0 377 390 1 1
CASP8 ANKMY2 0 0 44 184 1 1
CASP8 MAP3K5 0 900 596 958 1 1
CASP8 PSMC5 0 0 155 176 1 1
CASP8 IRF5 0 0 211 247 1 1
CASP8 RAC1 0 0 150 165 1 2
CASP8 HMGB1 0 0 406 416 1 2
CASP8 DUOX2 0 0 167 175 1 1
CASP8 CTSK 0 0 163 177 1 2
CASP8 LYN 0 0 436 480 1 1
CASP8 COL6A6 0 900 60 901 1 1
CASP8 COPS5 0 0 159 158 1 1
CASP8 ACTL6B 0 0 0 156 1 1
CASP8 POTEB3 0 0 0 155 1 1
CASP8 SPI1 0 0 205 222 1 1
CASP8 TP53BP1 0 0 194 231 1 1
CASP8 NOX1 0 0 294 309 1 1
CASP8 CTSB 0 0 469 491 1 2
CASP8 ERVW-1 0 0 171 171 1 1
CASP8 MCL1 0 0 755 825 1 2
CASP8 SIRT1 0 0 400 419 1 2
CASP8 HECTD3 270 0 0 282 1 1
CASP8 CCR7 0 0 182 220 1 1
CASP8 IKBKG 213 900 932 994 1 1
CASP8 RARA 0 0 157 173 1 2
CASP8 MAP4K4 213 0 83 289 1 1
CASP8 GPX1 0 0 232 300 1 1
CASP8 VTN 0 0 242 241 1 1
CASP8 NUMA1 0 0 155 154 1 1
CASP8 AKT3 0 0 235 279 1 2
CASP8 CXCR5 0 0 123 218 1 1
CASP8 DEDD2 486 0 690 833 1 1
CASP8 NUCB1 270 0 58 294 1 1
CASP8 SOD3 0 0 119 175 1 1
CASP8 MAP3K12 0 0 392 396 1 1
CASP8 GPX3 0 0 108 201 1 1
CASP8 RPS6KA1 0 0 312 312 1 1
CASP8 PACSIN2 0 0 292 309 1 1
CASP8 LATS1 0 0 103 155 1 1
CASP8 NCAM1 0 0 368 373 1 1
CASP8 TBX21 0 0 155 172 1 1
CASP8 DFFB 0 0 637 672 1 1
CASP8 ISG15 0 0 212 244 1 2
CASP8 ARID1A 0 0 247 246 1 1
CASP8 ADAM17 0 0 288 303 1 1
CASP8 SERPINB9 270 0 345 508 1 1
CASP8 NFKBIB 0 0 265 422 1 1
CASP8 SERPINB8 0 0 0 206 1 1
CASP8 TGFBR1 0 0 211 240 1 1
CASP8 ATG10 0 0 260 260 1 2
CASP8 S100A4 0 0 151 192 1 1
CASP8 HSPB2 0 0 458 474 1 1
CASP8 ANXA6 0 0 74 482 1 1
CASP8 CMA1 0 0 170 169 1 1
CASP8 HSPB1 0 0 457 477 1 2
CASP8 ENSG00000255819 0 0 231 265 1 1
CASP8 GLI1 0 0 211 223 1 2
CASP8 CDK7 0 0 194 194 1 1
CASP8 CCL20 0 0 218 218 1 1
CASP8 GFAP 0 0 295 310 1 2
CASP8 CXCL2 0 0 260 304 1 1
CASP8 COL1A1 0 900 180 914 1 2
CASP8 ITGB4 0 0 451 451 1 1
CASP8 GMNN 218 0 54 228 1 1
CASP8 NAMPT 0 0 150 173 1 2
CASP8 ATG7 0 0 509 550 1 2
CASP8 SELE 0 0 257 273 1 1
CASP8 TJP1 0 0 254 268 1 1
CASP8 TGFBR2 0 0 293 325 1 1
CASP8 TRAT1 0 0 158 186 1 1
CASP8 ACTG1 0 0 261 468 1 1
CASP8 FAIM2 0 0 150 205 1 1
CASP8 IKZF1 0 0 145 255 1 1
CASP8 ICAM3 0 0 124 171 1 1
CASP8 RET 0 0 167 167 1 1
CASP8 CTSD 0 0 415 432 1 2
CASP8 AXIN1 0 0 226 225 1 1
CASP8 IDH2 0 0 119 152 1 1
CASP8 TYRO3 0 0 113 157 1 1
CASP8 EZR 287 900 163 942 1 1
CASP8 SHC1 0 0 212 238 1 1
CASP8 ATM 0 800 556 909 1 2
CASP8 ENSG00000258947 0 0 150 288 1 1
CASP8 LMNB2 0 0 293 320 1 1
CASP8 TIMP3 0 0 325 325 1 1
CASP8 CD226 0 0 396 414 1 1
CASP8 MAPK14 270 0 421 698 1 2
CASP8 CTTNBP2 0 0 95 180 1 1
CASP8 CFL1 0 0 164 163 1 1
CASP8 SREBF1 0 0 206 206 1 1
CASP8 TP53BP2 0 0 233 280 1 2
CASP8 MAPK10 0 0 268 296 1 2
CASP8 HIST1H4A 0 0 218 218 1 1
CASP8 WT1 0 0 210 222 1 1
CASP8 MAP3K3 0 0 184 194 1 1
CASP8 ASAP2 0 0 0 163 1 1
CASP8 LEP 0 0 454 459 1 1
CASP8 SYK 0 0 358 414 1 2
CASP8 NFKBIA 0 0 716 756 1 2
CASP8 C12orf5 0 0 150 168 1 1
CASP8 CASP5 0 0 809 435 1 1
CASP8 DNM1L 0 650 369 787 1 2
CASP8 TRAF7 0 0 327 328 1 1
CASP8 WIPI1 0 0 135 225 1 2
CASP8 TXN2 0 0 107 182 1 1
CASP8 MAPK7 0 0 211 224 1 1
CASP8 IRF4 0 0 230 352 1 1
CASP8 ARID2 0 0 155 154 1 1
CASP8 VEGFA 0 0 562 562 1 2
CASP8 CYFIP2 0 0 184 195 1 1
CASP8 PTEN 270 0 559 674 1 2
CASP8 NEK7 0 0 218 246 1 1
CASP8 MBP 0 0 171 171 1 2
CASP8 COL6A3 0 900 0 900 1 1
CASP8 CYC1 0 0 205 206 1 1
CASP8 PECAM1 0 0 330 340 1 1
CASP8 PTK2B 0 0 150 155 1 1
CASP8 ENSG00000264813 0 0 171 171 1 1
CASP8 DNAJB7 0 0 341 341 1 1
CASP8 ENSG00000258973 0 0 0 498 1 1
CASP8 S100A10 0 0 96 178 1 1
CASP8 CCNE1 0 0 323 417 1 1
CASP8 TXN 0 0 381 438 1 1
CASP8 LCP1 0 0 0 186 1 1
CASP8 ANXA7 0 0 108 505 1 1
CASP8 MDK 0 0 91 183 1 1
CASP8 HIST2H4B 0 0 218 218 1 1
CASP8 CD38 0 0 180 203 1 2
CASP8 FDFT1 0 0 304 304 1 1
CASP8 RHEB 0 0 161 176 1 2
CASP8 CD46 0 0 150 170 1 2
CASP8 PLCE1 0 0 162 176 1 1
CASP8 ATP2A2 0 0 161 196 1 1
CASP8 NADSYN1 0 0 45 412 1 1
CASP8 COL7A1 0 900 0 900 1 1
CASP8 DFFA 0 0 612 630 1 1
CASP8 CARD18 0 0 263 263 1 1
CASP8 TUBA1A 0 0 46 156 1 1
CASP8 ACTA2 0 0 73 235 1 1
CASP8 NOS3 0 0 323 323 1 2
CASP8 JUND 0 0 181 205 1 1
CASP8 PRKAA1 0 0 134 176 1 2
CASP8 TNFRSF10D 0 0 652 799 1 1
CASP8 CCND1 0 0 654 678 1 2
CASP8 SORBS1 270 0 53 279 1 1
CASP8 CD19 0 0 305 321 1 1
CASP8 IFIT2 0 0 170 201 1 1
CASP8 GRAMD4 0 0 167 167 1 1
CASP8 ANXA2 0 0 170 506 1 1
CASP8 AFAP1L2 0 0 150 188 1 1
CASP8 IRAK2 0 0 258 307 1 1
CASP8 NCF1 0 0 218 263 1 1
CASP8 ACTR10 0 0 0 155 1 1
CASP8 RRAD 0 0 109 153 1 1
CASP8 HMGCR 0 0 173 173 1 1
CASP8 IFT43 0 0 527 527 1 1
CASP8 EIF4E 0 900 500 947 1 2
CASP8 PPP2CA 270 0 128 336 1 1
CASP8 PRKDC 0 0 242 254 1 2
CASP8 HIST2H2BE 0 0 179 179 1 1
CASP8 BAD 0 0 458 479 1 2
CASP8 CCND3 0 0 323 349 1 1
CASP8 SYNE1 0 0 123 224 1 1
CASP8 RNF41 0 0 359 360 1 1
CASP8 SOCS1 0 0 282 297 1 1
CASP8 BTK 0 0 233 285 1 1
CASP8 MAPK1 270 900 532 963 1 2
CASP8 IGF1 0 0 459 469 1 2
CASP8 CSF1R 0 0 206 206 1 1
CASP8 WDFY3 0 0 61 194 1 2
CASP8 GBP5 0 0 138 169 1 1
CASP8 PPP2R5C 0 0 57 157 1 1
CASP8 PKM 0 0 145 231 1 1
CASP8 RTN4IP1 0 0 74 214 1 1
CASP8 GADD45A 0 0 393 467 1 1
CASP8 BCL2A1 0 0 524 623 1 1
CASP8 TYMP 0 0 134 156 1 1
CASP8 TNFSF14 0 0 160 198 1 1
CASP8 PLEKHA4 270 0 0 270 1 1
CASP8 FGF2 0 0 385 390 1 2
CASP8 CXCL3 0 0 124 176 1 1
CASP8 BCAP31 766 900 607 990 1 1
CASP8 SDF2L1 0 0 0 188 1 1
CASP8 RELB 0 0 425 451 1 2
CASP8 EDEM1 0 0 125 170 1 2
CASP8 IREB2 0 0 120 152 1 1
CASP8 PTCH1 0 0 171 175 1 1
CASP8 POTEI 0 0 0 244 1 1
CASP8 VWF 0 0 150 185 1 1
CASP8 PRDX2 0 0 109 164 1 1
CASP8 CD63 0 0 170 169 1 2
CASP8 HIST1H4H 0 0 218 218 1 1
CASP8 IFNAR1 0 0 310 325 1 1
CASP8 SMPD2 0 0 322 344 1 1
CASP8 DDX3X 0 0 202 216 1 1
CASP8 CAP1 0 0 219 219 1 1
CASP8 NRIP1 0 0 94 191 1 1
CASP8 MMP7 0 0 277 310 1 1
CASP8 BAG4 0 0 294 294 1 1
CASP8 NME1 0 0 170 171 1 1
CASP8 VCL 0 0 439 439 1 1
CASP8 HIPK3 0 0 112 207 1 1
CASP8 CASP2 488 0 881 663 1 1
CASP8 IL7 0 0 243 259 1 1
CASP8 KIAA0141 0 0 235 235 1 1
CASP8 CD44 0 0 410 424 1 2
CASP8 BDNF 0 0 288 294 1 2
CASP8 TUBB4B 0 0 0 161 1 1
CASP8 TIRAP 0 0 293 308 1 1
CASP8 HSPA2 0 0 0 183 1 1
CASP8 DCK 0 0 142 151 1 1
CASP8 TANK 0 0 296 312 1 2
CASP8 RHAG 0 0 261 261 1 1
CASP8 YBX1 76 0 142 262 1 1
CASP8 PTRH2 0 0 140 193 1 1
CASP8 VMP1 0 0 146 196 1 2
CASP8 KMT2D 0 0 280 291 1 1
CASP8 COL4A3 0 900 63 902 1 1
CASP8 PSMD5 0 0 193 193 1 1
CASP8 E2F4 0 0 184 191 1 1
CASP8 ING1 0 0 135 171 1 1
CASP8 NOX4 0 0 181 181 1 2
CASP8 DROSHA 0 0 170 266 1 1
CASP8 NLRC4 675 0 854 952 1 2
CASP8 TPT1 0 0 161 180 1 1
CASP8 DUOX1 0 0 181 189 1 1
CASP8 CD247 0 0 150 157 1 1
CASP8 COL4A2 0 900 97 907 1 1
CASP8 NTRK2 0 0 170 189 1 1
CASP8 SDF2 0 0 67 322 1 1
CASP8 ATP7A 0 0 170 169 1 1
CASP8 HSPH1 0 0 55 158 1 1
CASP8 IFIT3 0 0 139 153 1 1
CASP8 VCAM1 0 0 294 315 1 1
CASP8 SUMO1 213 0 202 359 1 1
CASP8 FAS 914 900 987 999 1 2
CASP8 CSF2 0 0 413 423 1 1
CASP8 HIST1H4C 0 0 218 218 1 1
CASP8 DSG3 0 0 107 168 1 1
CASP8 YES1 0 0 134 182 1 1
CASP8 RHD 0 0 193 193 1 1
CASP8 DENR 0 0 162 161 1 1
CASP8 VEGFB 0 0 98 160 1 1
CASP8 TH 0 0 182 182 1 2
CASP8 NGF 0 0 391 395 1 2
CASP8 ACTL10 0 0 0 155 1 1
CASP8 CD34 0 0 364 375 1 2
CASP8 TUBAL3 0 0 0 151 1 1
CASP8 CARD6 0 0 242 280 1 1
CASP8 TNFSF8 0 0 182 204 1 1
CASP8 AIFM1 0 0 323 578 1 1
CASP8 KRT18 213 0 316 438 1 1
CASP8 CYLD 0 800 676 947 1 1
CASP8 EIF4EBP1 0 0 380 380 1 2
CASP8 TYMS 0 0 253 252 1 1
CASP8 USP25 0 0 108 184 1 1
CASP8 FOXO4 0 0 181 181 1 1
CASP8 AXL 0 0 194 229 1 2
CASP8 HSP90AB1 0 0 124 386 1 2
CASP8 BCL6 0 0 202 214 1 1
CASP8 PINK1 0 0 217 223 1 2
CASP8 GJA1 0 0 211 211 1 1
CASP8 GPT 0 0 403 403 1 1
CASP8 EWSR1 0 0 209 209 1 1
CASP8 TP53INP1 0 0 172 190 1 2
CASP8 HNF4A 0 0 233 232 1 1
CASP8 TXNDC9 0 0 205 254 1 1
CASP8 CD52 0 0 96 152 1 1
CASP8 MCRS1 0 0 329 329 1 1
CASP8 TLR3 270 600 959 987 1 2
CASP8 CDKN3 0 0 391 390 1 1
CASP8 BNIP1 0 0 141 161 1 2
CASP8 BIRC6 270 0 325 588 1 1
CASP8 DNAJB1 0 0 218 218 1 2
CASP8 ATG3 0 0 767 775 1 2
CASP8 MIF 0 0 162 161 1 2
CASP8 CDC42 0 0 290 303 1 2
CASP8 GPX6 0 0 56 200 1 1
CASP8 IRF8 0 0 150 185 1 1
CASP8 APOE 0 0 206 206 1 2
CASP8 SLC2A4 0 0 150 170 1 1
CASP8 VDAC3 0 0 181 186 1 1
CASP8 FOXO3 0 0 493 512 1 2
CASP8 FBXW5 0 0 81 362 1 1
CASP8 TNFSF11 0 0 305 310 1 2
CASP8 ACTG2 0 0 69 191 1 1
CASP8 PPIL3 0 0 148 162 1 1
CASP8 USP7 0 0 181 204 1 1
CASP8 PRKCD 0 0 458 469 1 2
CASP8 PARP10 270 0 0 270 1 1
CASP8 RIPK3 875 900 988 999 1 2
CASP8 MMP10 0 0 138 225 1 1
CASP8 STAT5B 0 0 321 335 1 1
CASP8 RAB7B 0 0 181 187 1 1
CASP8 VDAC1 0 0 559 559 1 2
CASP8 GADD45G 0 0 156 156 1 1
CASP8 TGFB1 0 0 325 365 1 2
CASP8 RASSF5 0 0 181 200 1 1
CASP8 GLUL 0 0 170 260 1 1
CASP8 SKP1 0 0 158 157 1 2
CASP8 KDR 0 0 297 309 1 2
CASP8 YY1 0 0 155 168 1 1
CASP8 RAC2 0 0 171 217 1 1
CASP8 TBK1 0 0 391 446 1 2
CASP8 ATG2B 0 0 82 171 1 2
CASP8 TUBB2A 0 0 0 175 1 1
CASP8 HIST1H4D 0 0 218 218 1 1
CASP8 FOXP3 0 0 325 331 1 2
CASP8 PTPN6 270 0 151 373 1 1
CASP8 NPAT 0 0 139 174 1 1
CASP8 HPGDS 0 0 369 369 1 1
CASP8 FBXW7 0 0 283 282 1 2
CASP8 IL3 0 0 260 260 1 1
CASP8 COX4I1 0 0 517 553 1 1
CASP8 RPL22 0 0 0 153 1 1
CASP8 HTRA2 0 0 593 609 1 1
CASP8 CEBPA 0 0 218 235 1 1
CASP8 RFK 0 0 143 166 1 1
CASP8 CD40 0 0 459 482 1 2
CASP8 STUB1 0 0 248 248 1 2
CASP8 DNMT1 0 0 325 332 1 2
CASP8 GTSE1 0 0 123 293 1 1
CASP8 INS 0 0 468 489 1 2
CASP8 AK2 0 0 397 412 1 1
CASP8 ACTB 0 0 740 795 1 2
CASP8 HIST1H4J 0 0 218 218 1 1
CASP8 GLI3 0 0 150 163 1 1
CASP8 F2RL2 0 0 397 396 1 1
CASP8 FCGR2B 0 0 194 211 1 1
CASP8 KEAP1 0 0 390 393 1 2
CASP8 B2M 0 0 268 324 1 1
CASP8 ANGPT1 0 0 193 193 1 1
CASP8 KMT2C 0 0 212 224 1 1
CASP8 PROM1 0 0 310 309 1 2
CASP8 SIRT3 0 0 249 248 1 2
CASP8 GSR 0 0 369 369 1 1
CASP8 UBE2L3 270 0 87 318 1 1
CASP8 HSPA8 0 0 282 392 1 2
CASP8 EIF4G1 0 900 218 919 1 2
CASP8 EPCAM 0 0 167 167 1 2
CASP8 RHOA 287 0 325 511 1 2
CASP8 PARP1 270 0 675 809 1 2
CASP8 NKRF 0 0 170 182 1 1
CASP8 BCLAF1 0 0 181 181 1 1
CASP8 TNFRSF14 0 0 172 190 1 1
CASP8 UBE2N 0 0 259 272 1 1
CASP8 IL36A 0 0 92 200 1 1
CASP8 CXCL12 0 0 282 282 1 2
CASP8 GMEB1 486 0 67 531 1 1
CASP8 TLR5 0 0 294 330 1 1
CASP8 LRRC59 0 0 0 167 1 1
CASP8 KLRK1 0 0 232 292 1 1
CASP8 PLA2G1B 0 0 181 181 1 1
CASP8 ESR2 0 0 476 487 1 1
CASP8 MLKL 246 0 845 927 1 2
CASP8 ARSE 0 0 241 240 1 1
CASP8 GABARAPL1 0 0 326 344 1 2
CASP8 OCA2 0 0 160 198 1 1
CASP8 TUBA1B 0 0 0 151 1 1
CASP8 SIRT7 0 0 216 216 1 2
CASP8 MYH9 0 0 112 182 1 1
CASP8 CD24 0 0 173 173 1 2
CASP8 ZEB1 0 0 235 235 1 2
CASP8 PSMD1 0 0 89 153 1 1
CASP8 HIP1 486 800 0 894 1 1
CASP8 TICAM1 270 900 542 964 1 2
CASP8 IL17RA 0 0 139 183 1 1
CASP8 LAMP2 0 0 231 247 1 2
CASP8 ACAP1 0 0 0 214 1 1
CASP8 YWHAE 0 0 123 194 1 1
CASP8 CAPN2 0 0 664 684 1 2
CASP8 NFKBIL1 0 0 124 164 1 1
CASP8 LCK 0 0 318 364 1 1
CASP8 MIB2 0 0 113 200 1 1
CASP8 CD69 0 0 234 265 1 1
CASP8 DNAJC3 0 0 150 188 1 1
CASP8 IL37 0 0 103 176 1 1
CASP8 CCR5 0 0 242 270 1 1
CASP8 CSNK1A1 0 0 136 154 1 1
CASP8 SHH 0 0 219 219 1 2
CASP8 ERN2 0 0 142 161 1 1
CASP8 PRDX1 0 0 155 274 1 1
CASP8 HAVCR2 0 0 193 210 1 1
CASP8 PSMB8 0 0 167 248 1 1
CASP8 ARID1B 0 0 193 193 1 1
CASP8 IGFBP3 0 0 297 297 1 2
CASP8 BIK 0 0 466 484 1 2
CASP8 CALR 0 0 387 417 1 1
CASP8 CD8A 0 0 558 558 1 1
CASP8 CRK 0 0 107 150 1 1
CASP8 TFAM 0 0 170 169 1 2
CASP8 RIPK2 213 900 391 951 1 2
CASP8 TNFRSF8 0 0 230 229 1 1
CASP8 SLAMF1 0 0 77 152 1 1
CASP8 MMP2 0 0 463 474 1 2
CASP8 EI24 0 0 134 152 1 2
CASP8 PLAT 0 0 134 228 1 1
CASP8 CXCL6 0 0 90 152 1 1
CASP8 SNCA 0 0 252 252 1 2
CASP8 ENSG00000233917 0 0 0 155 1 1
CASP8 CD74 0 0 134 163 1 1
CASP8 CD27 0 0 233 249 1 1
CASP8 CHEK1 128 0 463 517 1 2
CASP8 CASP1 270 800 915 916 1 2
CASP8 CCR3 0 0 95 156 1 1
CASP8 DEDD 675 0 810 936 1 1
CASP8 HSPA1A 0 0 234 396 1 1
CASP8 SRF 213 0 97 292 1 1
CASP8 CAV1 0 0 466 477 1 2
CASP8 TNFSF10 899 900 870 998 1 2
CASP8 MAP2K3 0 0 292 307 1 1
CASP8 CDC20 0 0 144 174 1 1
CASP8 ULK2 0 0 150 192 1 2
CASP8 HNRNPA1 0 0 139 158 1 1
CASP8 IL10RA 0 0 144 183 1 1
CASP8 PNMA3 0 0 170 169 1 1
CASP8 BCL2L11 0 0 736 783 1 2
CASP8 TAZ 0 0 181 203 1 1
CASP8 MAPK12 0 0 155 195 1 1
CASP8 PLCG1 0 0 262 275 1 1
CASP8 ITPR3 0 0 262 262 1 1
CASP8 TMEM173 0 0 143 183 1 1
CASP8 COL5A1 0 900 90 906 1 1
CASP8 TYR 0 0 211 240 1 2
CASP8 RDX 0 0 103 162 1 1
CASP8 POTEJ 0 0 0 244 1 1
CASP8 CX3CR1 0 0 160 159 1 1
CASP8 CDKN1C 0 0 163 163 1 1
CASP8 RPTOR 0 0 253 254 1 2
CASP8 NES 0 0 181 181 1 2
CASP8 NUCB2 270 0 0 282 1 1
CASP8 RPAP2 0 0 43 177 1 1
CASP8 ANXA13 0 0 71 574 1 1
CASP8 NANOG 0 0 218 218 1 2
CASP8 HK1 0 0 103 191 1 1
CASP8 CASP9 488 0 915 636 1 2
CASP8 ATG4A 0 0 113 166 1 2
CASP8 ITPR1 0 0 278 278 1 2
CASP8 TLR7 0 0 370 406 1 2
CASP8 IMMT 0 0 219 220 1 1
CASP8 MAPK9 0 0 452 470 1 2
CASP8 OGG1 0 0 155 154 1 1
CASP8 NRP1 0 0 125 158 1 1
CASP8 RPS6KA3 0 0 261 261 1 1
CASP8 CHEK2 0 0 504 522 1 1
CASP8 AKR1B1 0 0 180 195 1 1
CASP8 IL17A 0 0 346 350 1 2
CASP8 FASN 0 0 211 211 1 2
CASP8 ETS1 0 0 143 183 1 1
CASP8 MRPS30 0 0 246 245 1 1
CASP8 SH3RF1 0 0 207 207 1 1
CASP8 ACAP2 0 0 0 182 1 1
CASP8 ADIPOQ 0 0 233 232 1 2
CASP8 VIM 203 900 145 930 1 2
CASP8 SKP2 0 0 233 234 1 2
CASP8 GCLC 0 0 125 150 1 1
CASP8 NSMAF 0 0 73 158 1 1
CASP8 ARG1 0 0 232 231 1 2
CASP8 AURKB 0 0 243 249 1 1
CASP8 PAK2 0 0 165 166 1 1
CASP8 TNS1 0 0 263 268 1 1
CASP8 ACAP3 0 0 0 182 1 1
CASP8 GSDMB 0 0 156 155 1 1
CASP8 PXN 0 0 229 245 1 1
CASP8 HIST2H3PS2 0 0 393 406 1 1
CASP8 HSPA6 0 0 91 184 1 1
CASP8 FAM72A 0 0 45 150 1 1
CASP8 IFIH1 0 600 393 780 1 1
CASP8 RCSD1 0 0 0 191 1 1
CASP8 CTGF 0 0 231 230 1 1
CASP8 DAPK3 0 0 155 184 1 2
CASP8 FKBP1A 0 0 157 651 1 2
CASP8 MX2 0 0 230 334 1 1
CASP8 NR3C1 0 0 203 235 1 1
CASP8 IL2RG 0 0 114 190 1 1
CASP8 GLUD1 0 0 170 169 1 1
CASP8 PRF1 0 0 460 492 1 1
CASP8 CISH 0 0 213 213 1 1
CASP8 PTGER4 0 0 154 209 1 1
CASP8 DPP4 0 0 134 175 1 1
CASP8 BSG 0 0 209 209 1 1
CASP8 RNF31 0 0 454 454 1 1
CASP8 LGALS4 0 0 180 194 1 1
CASP8 CLDN12 0 0 181 187 1 1
CASP8 CCL4 0 0 260 276 1 1
CASP8 TFPI 0 0 62 210 1 1
CASP8 ZNF707 237 0 0 248 1 1
CASP8 IL1A 0 0 460 472 1 1
CASP8 MAVS 0 600 835 941 1 2
CASP8 H2AFX 0 0 455 455 1 1
CASP8 DNM2 0 0 90 154 1 1
CASP8 DCTN1 0 0 314 314 1 1
CASP8 IAPP 0 0 161 161 1 2
CASP8 HYOU1 0 0 95 188 1 1
CASP8 HIST1H4E 0 0 218 218 1 1
CASP8 MAPKAPK2 0 0 232 248 1 1
CASP8 AIM2 0 0 799 804 1 2
CASP8 DDX58 0 600 699 904 1 1
CASP8 HDAC8 0 0 171 171 1 1
CASP8 CDK6 0 0 465 502 1 2
CASP8 KMT2B 0 0 201 213 1 1
CASP8 PLG 0 0 283 297 1 1
CASP8 ZEB2 0 0 151 150 1 1
CASP8 BCL2L10 76 0 393 512 1 1
CASP8 BMP7 0 0 134 197 1 1
CASP8 GPX5 0 0 75 219 1 1
CASP8 NOTCH3 0 0 161 174 1 1
CASP8 CSNK2A2 0 0 193 203 1 1
CASP8 IL9 0 0 139 157 1 1
CASP8 MYLK 0 0 154 153 1 1
CASP8 CDK11B 213 0 62 230 1 1
CASP8 TNFRSF10A 897 900 972 999 1 1
CASP8 MADD 0 900 155 911 1 1
CASP8 TUBB3 0 0 90 226 1 1
CASP8 CD276 0 0 217 217 1 1
CASP8 SDHA 0 0 157 156 1 1
CASP8 UBAP2 0 0 0 157 1 1
CASP8 ITGB1 0 0 245 276 1 1
CASP8 TNFAIP8L2 0 0 955 967 1 1
CASP8 POTED 0 0 0 155 1 1
CASP8 XRCC6 0 0 268 268 1 1
CASP8 ERN1 0 0 518 542 1 2
CASP8 SIVA1 0 0 138 160 1 1
CASP8 MTAP 0 0 166 165 1 1
CASP8 NF2 0 0 171 207 1 1
CASP8 GATA3 0 0 246 245 1 1
CASP8 EIF4G3 0 900 145 912 1 1
CASP8 MKKS 0 0 128 196 1 1
CASP8 AGO2 0 0 151 176 1 2
CASP8 STAT3 0 0 601 627 1 2
CASP8 EZH2 0 0 253 264 1 2
CASP8 VDAC2 0 0 284 315 1 1
CASP8 HTRA1 0 0 155 178 1 1
CASP8 TSC22D3 270 0 95 311 1 1
CASP8 KARS 0 0 134 165 1 1
CASP8 COL2A1 0 900 104 906 1 2
CASP8 PDCD6 0 0 654 663 1 1
CASP8 CYBA 0 0 123 159 1 1
CASP8 SRSF1 0 0 193 193 1 1
CASP8 SH3BP5 0 0 134 169 1 1
CASP8 RALBP1 462 0 67 476 1 1
CASP8 CSF3 0 0 287 287 1 1
CASP8 LMNA 0 0 391 414 1 2
CASP8 HK2 0 0 135 244 1 2
CASP8 ACTRT1 0 0 0 155 1 1
CASP8 TRAF1 678 900 626 988 1 1
CASP8 DDIT3 0 0 565 576 1 2
CASP8 LCP2 0 0 116 157 1 1
CASP8 CRADD 213 900 529 964 1 1
CASP8 ERCC2 0 0 151 150 1 1
CASP8 TUBA4A 0 0 52 161 1 1
CASP8 PRKCI 111 0 68 155 1 1
CASP8 IRF9 0 0 218 235 1 1
CASP8 PRKCE 0 0 155 154 1 1
CASP8 COL5A2 0 900 0 900 1 1
CASP8 SARM1 0 0 144 319 1 1
CASP8 UCHL5 0 0 165 165 1 1
CASP8 FADD 992 900 990 999 1 2
CASP8 HIST1H4I 0 0 218 218 1 1
CASP8 CDK4 0 0 561 578 1 2
CASP8 ENSG00000278522 0 0 0 155 1 1
CASP8 PSTPIP1 0 0 97 231 1 1
CASP8 MYD88 0 0 554 624 1 2
CASP8 PAK7 0 0 148 166 1 1
CASP8 TLR1 0 0 323 419 1 1
CASP8 NFE2L2 0 0 391 390 1 2
CASP8 PGAM5 0 0 470 497 1 1
CASP8 AKT2 0 0 306 333 1 2
CASP8 PPP1R13B 0 0 134 153 1 1
CASP8 CIDEA 0 0 66 150 1 1
CASP8 UBE2K 0 0 140 173 1 1
CASP8 NLRP12 0 0 252 273 1 1
CASP8 CD80 0 0 304 319 1 2
CASP8 DSP 0 0 102 205 1 1
CASP8 FURIN 0 0 172 196 1 1
CASP8 RBCK1 0 0 391 391 1 1
CASP8 IKZF3 0 0 123 322 1 1
CASP8 DHX58 0 0 254 301 1 1
CASP8 MFF 0 0 234 234 1 1
CASP8 ODC1 0 0 216 241 1 1
CASP8 MAP2K1 0 0 423 440 1 1
CASP8 PPIF 0 0 464 490 1 1
CASP8 HIST1H4L 0 0 218 218 1 1
CASP8 MYCN 0 0 423 422 1 1
CASP8 SMAD4 0 0 314 313 1 2
CASP8 NOL3 675 0 321 776 1 1
CASP8 MAU2 0 0 235 235 1 1
CASP8 CIDEB 0 0 134 212 1 1
CASP8 TNFRSF13B 0 0 164 182 1 1
CASP8 TAX1BP1 0 0 167 167 1 2
CASP8 PARK7 270 0 171 369 1 2
CASP8 APPL1 0 0 0 182 1 1
CASP8 FKBP1B 0 0 0 293 1 1
CASP8 TRAF2 870 900 602 995 1 2
CASP8 ANXA9 0 0 95 395 1 1
CASP8 TAB1 0 0 342 346 1 1
CASP8 NOG 0 0 112 176 1 1
CASP8 MX1 0 0 234 303 1 1
CASP8 MEN1 0 0 433 440 1 1
CASP8 TUBA3E 0 0 0 151 1 1
CASP8 CASP8AP2 678 0 949 989 1 1
CASP8 PIK3CA 0 0 459 478 1 2
CASP8 MMP17 0 0 48 194 1 1
CASP8 APEX1 0 0 166 165 1 1
CASP8 PPIG 0 0 139 167 1 1
CASP8 IL1R1 0 0 391 404 1 1
CASP8 IRGM 0 0 194 211 1 2
CASP8 MYC 66 0 622 644 1 2
CASP8 IL18 0 0 562 608 1 2
CASP8 TAB2 0 0 457 464 1 2
CASP8 IGF1R 0 0 417 430 1 2
CASP8 COL11A1 0 900 81 909 1 1
CASP8 SDHC 0 0 252 252 1 1
CASP8 POLL 0 0 54 151 1 1
CASP8 TNFRSF6B 0 0 392 392 1 1
CASP8 H1F0 0 0 193 193 1 1
CASP8 PI3 0 0 255 254 1 2
CASP8 UBE2D1 270 0 108 332 1 1
CASP8 SMAD2 0 0 321 321 1 2
CASP8 TLR4 0 600 596 846 1 2
CASP8 TOPORS 270 0 73 310 1 1
CASP8 ATG14 0 0 251 250 1 2
CASP8 TNFRSF25 0 900 658 965 1 1
CASP8 CD14 0 600 53 625 1 1
CASP8 POTEE 0 0 0 244 1 1
CASP8 BRD1 258 0 0 258 1 1
CASP8 GABARAPL2 0 0 327 345 1 2
CASP8 NF1 0 0 261 261 1 1
CASP8 NOS2 0 0 289 304 1 2
CASP8 KITLG 0 0 181 181 1 1
CASP8 COL11A2 0 900 43 900 1 1
CASP8 PIK3R4 0 0 241 240 1 2
CASP8 CLEC7A 0 0 393 453 1 1
CASP8 TAB3 0 0 326 334 1 1
CASP8 XPA 0 0 160 159 1 1
CASP8 DNMT3A 0 0 236 242 1 2
CASP8 DNMT3B 0 0 244 260 1 1
CASP8 ENSG00000026036 0 0 392 392 1 1
CASP8 BCL2L1 682 0 900 976 1 2
CASP8 TUBB4A 0 0 522 581 1 1
CASP8 CCL4L1 0 0 158 176 1 1
CASP8 AOC3 0 0 158 157 1 1
CASP8 ANXA5 0 0 829 861 1 2
CASP8 CCNB1 0 0 595 624 1 1
CASP8 FOXM1 0 0 158 170 1 1
CASP8 LGALS9 0 0 151 185 1 1
CASP8 MGMT 0 0 420 432 1 2
CASP8 PERP 0 0 271 271 1 1
CASP8 HSPD1 0 0 214 266 1 1
CASP8 GSDMA 0 0 343 385 1 1
CASP8 CLEC4D 0 0 134 174 1 1
CASP8 PLK1 274 0 323 487 1 2
CASP8 PRDX6 270 0 93 309 1 1
CASP8 CXCL13 0 0 193 193 1 1
CASP8 EPO 0 0 262 266 1 2
CASP8 TNFSF9 0 0 134 227 1 1
CASP8 PLEC 213 900 459 957 1 1
CASP8 POMP 0 0 51 618 1 1
CASP8 PPFIA1 0 0 95 174 1 1
CASP8 KCNJ11 0 0 321 321 1 1
CASP8 IGFBP5 0 0 155 154 1 1
CASP8 HSPA1L 0 0 0 245 1 1
CASP8 IFNG 0 0 451 519 1 2
CASP8 BIRC2 835 900 760 997 1 1
CASP8 TUBB1 0 0 62 199 1 1
CASP8 PLCG2 0 0 163 195 1 1
CASP8 TGFB3 0 0 134 190 1 1
CASP8 CCL5 0 0 369 420 1 2
CASP8 CIDEC 0 0 0 207 1 1
CASP8 TWSG1 0 0 181 196 1 1
CASP8 UCP2 0 0 162 180 1 2
CASP8 PPP1R12A 0 0 108 153 1 1
CASP8 PALB2 0 0 184 183 1 1
CASP8 MPO 0 0 323 335 1 2
CASP8 SCAF11 0 0 381 381 1 1
CASP8 IL6 0 0 681 706 1 2
CASP8 RNASE1 0 0 260 260 1 1
CASP8 TCFL5 0 0 171 171 1 1
CASP8 TNFRSF1A 476 900 988 999 1 1
CASP8 RPS6 0 0 156 155 1 2
CASP8 E2F6 0 0 145 153 1 1
CASP8 TRAF4 0 0 304 305 1 1
CASP8 PIDD1 0 0 469 556 1 1
CASP8 RELL2 0 0 125 219 1 1
CASP8 PSEN2 213 0 108 284 1 1
CASP8 FGF13 0 0 181 181 1 1
CASP8 PTPN13 0 900 392 936 1 1
CASP8 NOTCH1 0 0 458 473 1 2
CASP8 PTGS1 0 0 155 189 1 1
CASP8 CD40LG 0 0 384 421 1 1
CASP8 NLRP1 0 0 460 471 1 1
CASP8 POTEF 0 0 247 407 1 1
CASP8 CALM1 0 0 107 176 1 1
CASP8 C4A 0 0 142 160 1 1
CASP8 FCGR3A 0 0 195 195 1 1
CASP8 MAP1LC3A 270 0 407 657 1 2
CASP8 CDK2 0 0 566 618 1 2
CASP8 ACTRT3 0 0 48 162 1 1
CASP8 EPHA2 0 0 158 177 1 1
CASP8 TRIM13 0 0 145 208 1 1
CASP8 PLA2G4A 0 0 123 155 1 1
CASP8 RHO 0 0 112 155 1 2
CASP8 CXCR2 0 0 183 213 1 1
CASP8 MYOM2 0 0 193 193 1 1
CASP8 NMT1 270 0 54 350 1 1
CASP8 TNFRSF1B 0 0 469 494 1 1
CASP8 PACS2 0 0 199 230 1 1
CASP8 XPO1 0 0 193 193 1 1
CASP8 TRPM7 0 0 193 208 1 1
CASP8 PRKCB 0 0 189 189 1 2
CASP8 EDN1 0 0 245 254 1 1
CASP8 HIF1A 0 0 502 517 1 2
CASP8 OAS1 0 0 155 179 1 1
CASP8 GCK 0 0 94 180 1 1
CASP8 PYGL 0 0 158 176 1 1
CASP8 TRAF5 0 0 585 601 1 1
CASP8 SIRT5 0 0 211 211 1 1
CASP8 SP1 0 0 321 346 1 2
CASP8 IL1B 0 900 683 975 1 2
CASP8 FAT1 0 0 456 456 1 1
CASP8 MAPK13 0 0 126 174 1 1
CASP8 CLN3 0 0 123 159 1 2
CASP8 ANXA8L1 0 0 74 173 1 1
CASP8 UBE2V1 270 0 181 376 1 1
CASP8 CARD16 0 0 291 597 1 1
CASP8 PLA2G6 0 0 201 216 1 1
CASP8 HDAC9 0 0 202 202 1 1
CASP8 BRCA2 0 0 391 390 1 1
CASP8 NLRP3 273 0 877 915 1 2
CASP8 REL 0 0 460 500 1 2
CASP8 TUBB6 0 0 0 161 1 1
CASP8 ERBB3 0 0 286 300 1 1
CASP8 CASP3 768 900 915 980 1 2
CASP8 PDIA6 111 0 81 201 1 1
CASP8 F3 0 0 183 184 1 1
CASP8 PTGS2 0 0 505 538 1 2
CASP8 TUBB2B 0 0 0 175 1 1
CASP8 TNFSF13B 0 0 235 242 1 1
CASP8 CTSS 0 0 123 231 1 1
CASP8 ACE 0 0 181 181 1 1
CASP8 PPM1B 0 0 167 172 1 1
CASP8 ASAH1 0 0 150 168 1 1
CASP8 TNFRSF10B 908 900 983 999 1 2
CASP8 IL13 0 0 272 272 1 2
CASP8 REN 0 0 150 192 1 1
CASP8 STK17B 0 0 113 183 1 1
CASP8 COL6A2 0 900 0 900 1 1
CASP8 EDA2R 270 0 90 326 1 1
CASP8 CYBB 0 0 282 298 1 2
CASP8 HDAC11 0 0 150 172 1 1
CASP8 VEGFC 0 0 166 213 1 1
CASP8 PTS 0 0 157 158 1 1
CASP8 ASZ1 0 0 91 152 1 1
CASP8 RPS27A 270 0 54 294 1 1
CASP8 GUSB 0 0 160 178 1 1
CASP8 CDKN2A 0 0 556 578 1 2
CASP8 GSK3B 0 0 329 423 1 2
CASP8 MRC1 0 0 156 174 1 1
CASP8 EIF3A 0 900 60 901 1 1
CASP8 S100B 0 0 176 175 1 1
CASP8 MTCH2 0 0 202 348 1 1
CASP8 GPX8 0 0 0 303 1 1
CASP8 CCNG1 0 0 134 175 1 1
CASP8 IL1RAP 0 0 167 167 1 1
CASP8 KIFAP3 0 0 306 306 1 1
CASP8 COL4A5 0 900 0 900 1 1
CASP8 PDIA4 0 0 92 215 1 1
CASP8 CIITA 0 0 181 241 1 1
CASP8 NOD2 0 0 390 430 1 2
CASP8 PIK3CD 0 0 123 175 1 1
CASP8 SMPD1 270 0 420 568 1 1
CASP8 CEBPB 270 0 426 573 1 2
CASP8 ATG16L1 0 0 431 431 1 2
CASP8 TXNRD1 0 0 217 223 1 1
CASP8 LTBR 0 0 263 297 1 1
CASP8 WNT3 0 0 112 170 1 1
CASP8 RIPK1 913 900 989 999 1 2
CASP8 TUBA8 0 0 0 151 1 1
CASP8 FASLG 871 900 948 999 1 1
CASP8 SOCS3 0 0 260 276 1 1
CASP8 GALNT14 0 0 163 163 1 1
CASP8 STAT5A 0 0 323 337 1 1
CASP8 RXRA 0 0 107 150 1 1
CASP8 BIRC7 0 0 501 619 1 1
CASP8 XAF1 0 0 391 419 1 1
CASP8 TNIP2 0 0 243 242 1 1
CASP8 FAF1 678 900 834 994 1 1
CASP8 TNIP1 0 0 229 257 1 1
CASP8 ITGB2 0 0 134 175 1 1
CASP8 KRAS 0 0 422 490 1 2
CASP8 MAPT 270 0 210 398 1 2
CASP8 BECN1 270 0 662 778 1 2
CASP8 THBS1 0 0 290 305 1 1
CASP8 ABCB1 0 0 327 350 1 2
CASP8 TLR6 0 0 246 395 1 1
CASP8 IL2 0 0 504 515 1 1
CASP8 ANXA1 0 0 233 279 1 1
CASP8 OLR1 0 0 170 189 1 2
CASP8 LRP1 0 0 193 193 1 1
CASP8 COX4I2 0 0 234 247 1 1
CASP8 ABCC1 0 0 255 254 1 1
CASP8 FLT4 0 0 161 161 1 1
CASP8 MAPK11 0 0 205 305 1 1
CASP8 DUSP1 0 0 248 248 1 1
CASP8 PIAS1 213 0 115 294 1 1
CASP8 SLC45A2 0 0 159 176 1 1
CASP8 AMH 0 0 66 159 1 1
CASP8 CDKN2C 0 0 142 261 1 1
CASP8 HSH2D 0 0 390 426 1 1
CASP8 MLH1 0 0 294 294 1 1
CASP8 ERLIN2 270 0 48 275 1 1
CASP8 POTEH 0 0 0 155 1 1
CASP8 POTEC 0 0 0 155 1 1
CASP8 CDC25A 0 0 324 353 1 1
CASP8 CD81 0 0 181 186 1 1
CASP8 NIF3L1 0 0 184 202 1 1
CASP8 CARD11 270 0 820 866 1 1
CASP8 YAP1 0 0 202 216 1 2
CASP8 CXCR3 0 0 181 231 1 1
CASP8 IRF1 0 0 394 451 1 2
CASP8 ATP4A 0 0 156 197 1 1
CASP8 EDAR 0 0 383 383 1 1
CASP8 PRKD1 0 0 150 169 1 1
CASP8 LGR5 0 0 155 180 1 1
CASP8 MYO7A 0 0 428 450 1 1
CASP8 ACTBL2 0 0 0 155 1 1
CASP8 SMAD7 0 0 217 217 1 1
CASP8 PDCD1 0 0 181 182 1 2
CASP8 OPTN 270 0 453 583 1 2
CASP8 ESR1 0 0 517 526 1 2
CASP8 MSH2 0 0 214 214 1 1
CASP8 IFNB1 0 0 519 533 1 1
CASP8 NCL 273 0 171 372 1 2
CASP8 NSD1 0 0 282 293 1 1
CASP8 DFNA5 0 0 402 412 1 1
CASP8 LMNB1 0 0 369 393 1 1
CASP8 BAI1 0 0 160 159 1 1
CASP8 ST8SIA2 0 0 126 157 1 1
CASP8 IL10RB 0 0 113 151 1 1
CASP8 RAG2 0 0 129 217 1 1
CASP8 RAD51B 0 0 244 245 1 1
CASP8 TBP 0 0 175 181 1 1
CASP8 FN1 0 0 424 444 1 2
CASP8 C3 0 0 207 225 1 2
CASP8 MMP13 0 0 193 210 1 2
CASP8 DST 0 0 48 172 1 2
CASP8 PRKCA 0 0 302 302 1 1
CASP8 ELANE 0 0 243 242 1 1
CASP8 MRPL44 0 0 0 151 1 1
CASP8 STXBP4 0 0 159 158 1 1
CASP8 PLK3 0 0 150 183 1 1
CASP8 RIPK4 0 0 171 257 1 1
CASP8 EIF4G2 0 900 74 905 1 1
CASP8 SETD2 0 0 150 179 1 1
CASP8 CDC25B 0 0 214 232 1 1
CASP8 ULK1 0 0 297 316 1 2
CASP8 MAP1LC3B 278 0 716 812 1 2
CASP8 TIMP2 0 0 262 262 1 1
CASP8 SPHK2 0 0 181 181 1 1
CASP8 UBC 270 0 71 306 1 2
CASP8 AGFG1 0 0 95 153 1 1
CASP8 SERPINB5 59 0 202 222 1 1
CASP8 SPHK1 0 0 213 213 1 2
CASP8 UBAP2L 0 0 0 303 1 1
CASP8 COL4A6 0 900 0 900 1 1
CASP8 TERT 0 0 394 407 1 2
CASP8 TET2 0 0 117 167 1 2
CASP8 TYRP1 0 0 205 205 1 1
CASP8 VAV1 0 0 165 225 1 1
CASP8 NCF2 0 0 155 196 1 1
CASP8 SNAI1 0 0 324 338 1 1
CASP8 IL10 0 0 517 540 1 2
CASP8 CLIP3 270 0 117 327 1 1
CASP8 IRAK4 0 0 321 404 1 1
CASP8 DAPK2 0 0 167 167 1 2
CASP8 RYBP 462 0 173 566 1 1
CASP8 NPM1 0 0 218 227 1 1
CASP8 FLT3 0 0 232 231 1 2
CASP8 CCAR1 0 0 120 159 1 1
CASP8 CCNL1 243 0 0 242 1 1
CASP8 NR1H4 270 0 161 373 1 1
CASP8 GDF15 0 0 180 197 1 1
CASP8 AREL1 0 0 63 176 1 1
CASP8 LITAF 0 0 91 164 1 1
CASP8 HLA-A 0 0 211 211 1 1
CASP8 MDM4 0 0 269 302 1 1
CASP8 CCL3 0 0 294 314 1 1
CASP8 CTSG 0 0 230 229 1 1
CASP8 FCGR3B 0 0 194 194 1 1
CASP8 TNFRSF10C 0 0 660 804 1 1
CASP8 IGF2 0 0 261 276 1 1
CASP8 CLEC4E 0 0 259 275 1 1
CASP8 TNFRSF9 0 0 243 261 1 1
CASP8 FCGR2A 0 0 165 183 1 1
CASP8 HIST1H4K 0 0 218 218 1 1
CASP8 NGFR 0 0 348 347 1 1
CASP8 E2F3 0 0 202 209 1 1
CASP8 BAG1 0 0 290 290 1 2
CASP8 CHFR 0 0 218 218 1 1
CASP8 RARB 0 0 234 249 1 1
CASP8 AMBRA1 0 0 285 284 1 2
CASP8 LDHA 0 0 134 150 1 2
CASP8 KIT 0 0 297 297 1 2
CASP8 COMMD3-BMI1 0 0 173 173 1 1
CASP8 CCNA1 0 0 202 208 1 1
CASP8 ACTL7A 0 0 0 155 1 1
CASP8 NTRK3 0 0 118 161 1 1
CASP8 GAPDHS 0 0 0 303 1 1
CASP8 PDCD1LG2 0 0 167 185 1 1
CASP8 MMP11 0 0 94 196 1 1
CASP8 AASDHPPT 0 0 107 162 1 1
CASP8 NFATC1 0 0 187 205 1 2
CASP8 E2F5 0 0 166 173 1 1
CASP8 CHL1 0 0 397 397 1 1
CASP8 NLRP6 0 0 325 348 1 1
CASP8 ACTR1A 0 0 0 155 1 1
CASP8 SLC9C2 0 0 0 152 1 1
CASP8 GSDMC 0 0 150 219 1 1
CASP8 COL6A5 0 900 0 900 1 1
CASP8 PDPK1 0 0 166 198 1 2
CASP8 CAT 0 0 558 584 1 2
CASP8 BARD1 0 0 204 261 1 1
CASP8 VPS41 0 0 474 474 1 1
CASP8 HGF 0 0 293 308 1 2
CASP8 POU5F1 0 0 210 210 1 2
CASP8 HRK 0 0 500 512 1 1
CASP8 CAST 0 0 344 361 1 2
CASP8 ATG2A 0 0 112 198 1 2
CASP8 GRIA1 213 0 70 236 1 1
CASP8 CANX 0 0 310 309 1 2
CASP8 BAK1 0 0 592 667 1 2
CASP8 PTPN2 0 0 123 198 1 2
CASP8 AVEN 0 0 203 204 1 1
CASP8 BCL2 681 0 395 838 1 2
CASP8 MYB 0 0 173 206 1 1
CASP8 DDIT4 0 0 181 181 1 2
CASP8 RNASEL 0 0 213 352 1 1
CASP8 HPRT1 0 0 218 218 1 1
CASP8 FAH 0 0 143 401 1 1
CASP8 CTLA4 0 0 456 467 1 2
CASP8 BLM 168 0 0 167 1 2
CASP8 LIN28A 0 0 96 274 1 1
CASP8 RCC1 0 0 166 165 1 1
CASP8 HDAC7 270 0 180 375 1 1
CASP8 AIMP1 0 0 0 248 1 1
CASP8 CD274 0 0 325 345 1 2
CASP8 BCL2L2 0 0 606 676 1 1
CASP8 ATR 0 0 202 215 1 2
CASP8 ABCG2 0 0 284 289 1 1
CASP8 SGK1 0 0 151 187 1 2
CASP8 IRS1 0 0 270 270 1 2
CASP8 EFS 0 0 325 325 1 1
CASP8 HSPA9 0 0 166 252 1 1
CASP8 CBL 0 0 247 260 1 1
CASP8 LOX 0 0 261 277 1 2
CASP8 GNLY 0 0 134 152 1 1
CASP8 NTRK1 0 0 271 287 1 1
CASP8 SESN1 0 0 155 154 1 1
CASP8 PGR 0 0 322 335 1 1
CASP8 HIST1H4B 0 0 218 218 1 1
CASP8 MUC1 0 0 782 782 1 1
CASP8 NLRP2 0 0 113 153 1 1
CASP8 CDK1 0 0 517 540 1 2
CASP8 NCOR1 0 0 228 227 1 1
CASP8 LEPREL2 0 0 261 261 1 1
CASP8 SERPINE1 0 0 261 292 1 1
CASP8 AHR 0 0 218 235 1 2
CASP8 CRBN 0 0 150 183 1 1
CASP8 TNFAIP8 0 0 322 452 1 1
CASP8 RPS6KB1 0 0 464 476 1 2
CASP8 REM1 0 0 0 318 1 1
CASP8 FCGR1A 0 0 181 198 1 1
CASP8 FHIT 0 0 265 265 1 1
CASP8 IRF7 0 0 373 400 1 1
CASP8 ITIH4 0 0 456 456 1 1
CASP8 PARP3 0 0 68 165 1 1
CASP8 MMP27 0 0 0 206 1 1
CASP8 UVRAG 0 0 263 263 1 2
CASP8 DDX53 0 0 263 276 1 1
CASP8 CDH5 0 0 142 181 1 1
CASP8 ATF3 0 0 308 323 1 2
CASP8 MMP8 0 0 134 257 1 1
CASP8 IFI16 0 0 230 248 1 1
CASP8 FKBP1C 0 0 53 608 1 1
CASP8 TXNIP 0 0 232 248 1 2
CASP8 SRSF2 0 0 204 204 1 1
CASP8 BMF 0 0 505 546 1 1
CASP8 RAB7A 0 0 180 186 1 2
CASP8 DRAM1 0 0 256 288 1 2
CASP8 GSTP1 0 0 380 380 1 1
CASP8 NFKB2 0 0 452 500 1 1
CASP8 ATG4B 0 0 183 221 1 2
CASP8 ATP12A 0 0 157 198 1 1
CASP8 SPN 0 0 109 161 1 1
CASP8 GCG 0 0 167 167 1 1
CASP8 EMP3 0 0 108 173 1 1
CASP8 TNFAIP3 675 0 401 811 1 2
CASP8 IL5 0 0 243 242 1 1
CASP8 RPS6KA2 0 0 241 240 1 1
CASP8 SDCBP 0 0 472 481 1 1
CASP8 IL1R2 0 0 134 173 1 1
CASP8 CD70 0 0 180 179 1 1
CASP8 MAP3K14 486 900 184 955 1 1
CASP8 TFRC 0 0 260 260 1 1
CASP8 CCND2 0 0 296 296 1 1
CASP8 PPP1R15A 0 0 322 326 1 2
CASP8 USP14 0 0 181 186 1 2
CASP8 POTEB2 0 0 0 155 1 1
CASP8 EEF2 0 0 150 190 1 2
CASP8 ITCH 0 0 232 254 1 1
CASP8 FMR1 103 0 74 165 1 1
CASP8 SLC7A11 0 0 163 163 1 2
CASP8 RBFOX3 0 0 218 245 1 1
CASP8 RNF135 0 600 73 622 1 1
CASP8 NFAT5 0 0 97 171 1 1
CASP8 WIPI2 0 0 81 176 1 2
CASP8 PEBP1 0 0 171 172 1 1
CASP8 FIS1 270 0 459 597 1 2
CASP8 NAIP 0 0 455 560 1 1
CASP8 FAIM3 0 0 359 359 1 1
CASP8 VDR 0 0 156 196 1 2
CASP8 FAIM 0 0 157 156 1 1
CASP8 IL1RN 0 0 456 494 1 1
CASP8 MMP3 0 0 283 332 1 1
CASP8 ITK 0 0 95 169 1 1
CASP8 MMP25 0 0 0 151 1 1
CASP8 C22orf29 0 0 718 718 1 1
CASP8 TNF 270 900 815 989 1 2
CASP8 NBR1 0 0 202 215 1 2
CASP8 XIAP 678 0 855 970 1 2
CASP8 UBR2 0 0 713 739 1 1
CASP8 PPP2R4 0 0 499 499 1 1
CASP8 RUNX2 0 0 231 231 1 2
CASP8 KCNJ6 0 0 235 235 1 1
CASP8 COL1A2 0 900 113 907 1 1
CASP8 ATF6 0 0 502 521 1 2
CASP8 IKBKB 270 900 563 969 1 2
CASP8 GSTM1 0 0 169 185 1 1
CASP8 COL6A1 0 900 57 901 1 1
CASP8 PANX1 0 0 260 274 1 1
CASP8 KLF4 0 0 159 172 1 2
CASP8 FGFR1 0 0 218 218 1 1
CASP8 RRM1 0 0 447 447 1 1
CASP8 CD4 0 0 558 584 1 2
CASP8 ATF4 0 0 324 323 1 2
CASP8 USO1 213 0 0 213 1 1
CASP8 SYNE2 0 0 82 222 1 1
CASP8 TUBA3C 0 0 57 165 1 1
CASP8 CARD14 0 0 112 167 1 1
CASP8 CARD8 0 0 252 278 1 1
CASP8 PCYT1A 213 0 0 281 1 1
CASP8 ACTL8 0 0 0 155 1 1
CASP8 LY96 0 600 203 674 1 1
CASP8 MKI67 0 0 134 385 1 2
CASP8 AKT1 0 0 751 766 1 2
CASP8 GBP2 0 0 103 159 1 1
CASP8 TGFB2 0 0 203 203 1 1
CASP8 CAPN1 0 0 507 527 1 2
CASP8 PPARG 0 0 402 427 1 2
CASP8 UBE3A 0 0 228 241 1 1
CASP8 NLRP7 0 0 210 246 1 1
CASP8 CTSC 0 0 134 194 1 1
CASP8 BBC3 0 0 501 501 1 2
CASP8 ERBB2 0 0 517 531 1 2
CASP8 HMGA2 0 0 155 154 1 1
CASP8 ARG2 0 0 174 173 1 1
CASP8 IRF3 0 0 505 505 1 2
CASP8 TLR9 0 0 395 436 1 2
CASP8 CCNE2 0 0 219 272 1 1
CASP8 CD1D 0 0 150 181 1 1
CASP8 MAP3K1 0 0 598 606 1 1
CASP8 PYCARD 675 800 667 979 1 2
CASP8 RHOC 0 0 134 150 1 1
CASP8 BIRC8 0 0 402 642 1 1
CASP8 MALT1 270 800 951 992 1 1
CASP8 CXCL10 0 0 342 361 1 2
CASP8 GAS2 0 0 113 211 1 1
CASP8 IL24 59 0 294 328 1 2
CASP8 GSK3A 0 0 113 178 1 1
CASP8 SIRT4 0 0 203 203 1 1
CASP8 BIRC5 0 0 391 497 1 2
CASP8 WWOX 0 0 123 177 1 1
CASP8 CCNG2 0 0 123 159 1 1
CASP8 STAT6 0 0 204 261 1 1
CASP8 TUBB8B 0 0 0 161 1 1
CASP8 TNFSF12 0 900 464 944 1 1
CASP8 EIF2AK3 0 0 594 602 1 2
CASP8 PSMB5 0 0 134 183 1 1
CASP8 VHL 128 0 90 172 1 2
CASP8 CADM1 0 0 252 252 1 1
CASP8 FLT1 0 0 261 261 1 1
CASP8 TUBB8 0 0 0 161 1 1
CASP8 CIB1 0 0 143 175 1 1
CASP8 SLC25A5 0 0 123 257 1 1
CASP8 LGALS3 0 0 289 316 1 2
CASP8 TUBA1C 0 0 0 151 1 1
CASP8 ATG4C 0 0 150 204 1 2
CASP8 DAP3 0 900 208 917 1 1
CASP8 SRC 486 0 963 981 1 2
CASP8 ACTL6A 0 0 0 164 1 1
CASP8 YWHAB 0 0 155 182 1 1
CASP8 PCSK9 0 0 164 182 1 1
CASP8 IL36B 0 0 82 191 1 1
CASP8 SHISA5 0 0 150 327 1 1
CASP8 MCU 0 0 181 181 1 2
CASP8 USP2 270 0 124 346 1 1
CASP8 CD47 0 0 208 226 1 2
CASP8 DHFRL1 0 0 0 241 1 1
CASP8 SPTAN1 0 0 298 372 1 1
CASP8 CTCF 0 0 155 168 1 1
CASP8 CD2 0 0 150 195 1 1
CASP8 CDKN1B 408 0 468 682 1 2
CASP8 RB1 270 0 295 475 1 2
CASP8 IFIT1 0 0 203 233 1 1
CASP8 HACE1 0 0 61 167 1 1
CASP8 PPM1D 0 0 161 161 1 1
CASP8 TSC2 0 0 278 282 1 2
CASP8 BNIP3L 0 0 283 546 1 2
CASP8 F2R 0 0 154 153 1 1
CASP8 EIF2S1 0 0 508 511 1 2
CASP8 MMP12 0 0 167 191 1 1
CASP8 ANPEP 0 0 142 179 1 1
CASP8 RASSF1 0 0 470 470 1 1
CASP8 HCN1 0 0 0 303 1 1
CASP8 MITF 0 0 182 197 1 2
CASP8 JAK1 0 0 341 374 1 2
CASP8 COX11 0 0 249 248 1 1
CASP8 NFATC2 0 0 181 181 1 1
CASP8 TOMM20 0 0 253 270 1 2
CASP8 A26B3 0 0 0 155 1 1
CASP8 TCHP 0 0 468 468 1 1
CASP8 TICAM2 0 600 174 658 1 1
CASP8 LRRK1 0 0 74 160 1 1
CASP8 LIN28B 0 0 96 194 1 1
CASP8 RHOH 0 0 74 153 1 1
CASP8 GLRX 0 0 213 213 1 1
CASP8 HMOX1 0 0 459 459 1 2
CASP8 IL32 0 0 170 190 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0004197 Molecular Function cysteine-type endopeptidase activity enables IDA
GO:0004197 Molecular Function cysteine-type endopeptidase activity enables TAS
GO:0097153 Molecular Function cysteine-type endopeptidase activity involved in apoptotic process enables IDA
GO:0097153 Molecular Function cysteine-type endopeptidase activity involved in apoptotic process enables IMP
GO:0097199 Molecular Function cysteine-type endopeptidase activity involved in apoptotic signaling pathway enables IBA
GO:0097199 Molecular Function cysteine-type endopeptidase activity involved in apoptotic signaling pathway enables IDA
GO:0097199 Molecular Function cysteine-type endopeptidase activity involved in apoptotic signaling pathway enables IMP
GO:0008234 Molecular Function cysteine-type peptidase activity enables TAS
GO:0035877 Molecular Function death effector domain binding enables IBA
GO:0035877 Molecular Function death effector domain binding enables IPI
GO:0005123 Molecular Function death receptor binding enables IEA
GO:0042802 Molecular Function identical protein binding enables IPI
GO:0008233 Molecular Function peptidase activity enables IDA
GO:0008233 Molecular Function peptidase activity enables IMP
GO:0005515 Molecular Function protein binding enables IPI
GO:0044877 Molecular Function protein-containing complex binding enables IEA
GO:0097110 Molecular Function scaffold protein binding enables IPI
GO:0005164 Molecular Function tumor necrosis factor receptor binding enables IEA
GO:0031625 Molecular Function ubiquitin protein ligase binding enables IPI
GO:0042113 Biological Process B cell activation involved_in TAS
GO:0042110 Biological Process T cell activation involved_in TAS
GO:0036462 Biological Process TRAIL-activated apoptotic signaling pathway involved_in IDA
GO:0097202 Biological Process activation of cysteine-type endopeptidase activity involved_in IDA
GO:0006919 Biological Process activation of cysteine-type endopeptidase activity involved in apoptotic process involved_in IBA
GO:0001525 Biological Process angiogenesis involved_in ISS
GO:0006915 Biological Process apoptotic process involved_in IBA
GO:0006915 Biological Process apoptotic process involved_in IMP
GO:0097190 Biological Process apoptotic signaling pathway involved_in IMP
GO:0097190 Biological Process apoptotic signaling pathway involved_in TAS
GO:0071260 Biological Process cellular response to mechanical stimulus involved_in IEP
GO:0071407 Biological Process cellular response to organic cyclic compound involved_in IEA
GO:0097194 Biological Process execution phase of apoptosis involved_in IMP
GO:0097194 Biological Process execution phase of apoptosis involved_in ISS
GO:0097191 Biological Process extrinsic apoptotic signaling pathway involved_in IDA
GO:0008625 Biological Process extrinsic apoptotic signaling pathway via death domain receptors involved_in IBA
GO:0007507 Biological Process heart development involved_in ISS
GO:0030225 Biological Process macrophage differentiation involved_in IBA
GO:0030225 Biological Process macrophage differentiation involved_in TAS
GO:0030101 Biological Process natural killer cell activation involved_in TAS
GO:0043124 Biological Process negative regulation of canonical NF-kappaB signal transduction involved_in IMP
GO:0060546 Biological Process negative regulation of necroptotic process involved_in IDA
GO:0060546 Biological Process negative regulation of necroptotic process involved_in ISS
GO:0043065 Biological Process positive regulation of apoptotic process involved_in ISS
GO:0043123 Biological Process positive regulation of canonical NF-kappaB signal transduction involved_in IEP
GO:0043123 Biological Process positive regulation of canonical NF-kappaB signal transduction involved_in IMP
GO:0032731 Biological Process positive regulation of interleukin-1 beta production involved_in IMP
GO:0045651 Biological Process positive regulation of macrophage differentiation involved_in IMP
GO:0043525 Biological Process positive regulation of neuron apoptotic process involved_in IEA
GO:0045862 Biological Process positive regulation of proteolysis involved_in IDA
GO:0051604 Biological Process protein maturation involved_in IDA
GO:0006508 Biological Process proteolysis involved_in IDA
GO:0051603 Biological Process proteolysis involved in protein catabolic process involved_in IMP
GO:0051603 Biological Process proteolysis involved in protein catabolic process involved_in ISS
GO:0070269 Biological Process pyroptosis involved_in ISS
GO:0001817 Biological Process regulation of cytokine production involved_in ISS
GO:0045088 Biological Process regulation of innate immune response involved_in ISS
GO:0010803 Biological Process regulation of tumor necrosis factor-mediated signaling pathway involved_in TAS
GO:0032025 Biological Process response to cobalt ion involved_in IEA
GO:0032355 Biological Process response to estradiol involved_in IEA
GO:0045471 Biological Process response to ethanol involved_in IEA
GO:0032496 Biological Process response to lipopolysaccharide involved_in IEA
GO:0034612 Biological Process response to tumor necrosis factor involved_in IMP
GO:0097264 Biological Process self proteolysis involved_in ISS
GO:0060715 Biological Process syncytiotrophoblast cell differentiation involved in labyrinthine layer development involved_in TAS
GO:0031265 Cellular Component CD95 death-inducing signaling complex part_of IDA
GO:0044297 Cellular Component cell body located_in IEA
GO:0005737 Cellular Component cytoplasm is_active_in IBA
GO:0005737 Cellular Component cytoplasm is_active_in IDA
GO:0005856 Cellular Component cytoskeleton located_in TAS
GO:0005829 Cellular Component cytosol located_in IDA
GO:0005829 Cellular Component cytosol located_in TAS
GO:0031264 Cellular Component death-inducing signaling complex part_of IDA
GO:0005741 Cellular Component mitochondrial outer membrane located_in TAS
GO:0005739 Cellular Component mitochondrion located_in TAS
GO:0005654 Cellular Component nucleoplasm located_in IDA
GO:0032991 Cellular Component protein-containing complex part_of IDA
GO:0097342 Cellular Component ripoptosome part_of IDA
Pathways
Name DB ID
Apoptosis Reactome R-HSA-109581
Intrinsic Pathway for Apoptosis Reactome R-HSA-109606
Apoptotic cleavage of cellular proteins Reactome R-HSA-111465
Cytokine Signaling in Immune system Reactome R-HSA-1280215
Caspase activation via Death Receptors in the presence of ligand Reactome R-HSA-140534
Signal Transduction Reactome R-HSA-162582
Disease Reactome R-HSA-1643685
Toll Like Receptor 4 (TLR4) Cascade Reactome R-HSA-166016
MyD88:MAL(TIRAP) cascade initiated on plasma membrane Reactome R-HSA-166058
MyD88-independent TLR4 cascade Reactome R-HSA-166166
Toll Like Receptor 9 (TLR9) Cascade Reactome R-HSA-168138
Toll Like Receptor 10 (TLR10) Cascade Reactome R-HSA-168142
Toll Like Receptor 3 (TLR3) Cascade Reactome R-HSA-168164
Toll Like Receptor 5 (TLR5) Cascade Reactome R-HSA-168176
Toll Like Receptor TLR1:TLR2 Cascade Reactome R-HSA-168179
Toll Like Receptor 7/8 (TLR7/8) Cascade Reactome R-HSA-168181
Toll Like Receptor TLR6:TLR2 Cascade Reactome R-HSA-168188
Innate Immune System Reactome R-HSA-168249
Immune System Reactome R-HSA-168256
NOD1/2 Signaling Pathway Reactome R-HSA-168638
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways Reactome R-HSA-168643
Toll-like Receptor Cascades Reactome R-HSA-168898
DDX58/IFIH1-mediated induction of interferon-alpha/beta Reactome R-HSA-168928
Toll Like Receptor 2 (TLR2) Cascade Reactome R-HSA-181438
TRIF-mediated programmed cell death Reactome R-HSA-2562578
Caspase-mediated cleavage of cytoskeletal proteins Reactome R-HSA-264870
Regulation by c-FLIP Reactome R-HSA-3371378
TAK1-dependent IKK and NF-kappa-B activation Reactome R-HSA-445989
Interleukin-1 family signaling Reactome R-HSA-446652
Signaling by Interleukins Reactome R-HSA-449147
RIPK1-mediated regulated necrosis Reactome R-HSA-5213460
Regulated Necrosis Reactome R-HSA-5218859
CASP8 activity is inhibited Reactome R-HSA-5218900
Caspase activation via extrinsic apoptotic signalling pathway Reactome R-HSA-5357769
TNFR1-induced proapoptotic signaling Reactome R-HSA-5357786
Programmed Cell Death Reactome R-HSA-5357801
Regulation of TNFR1 signaling Reactome R-HSA-5357905
CLEC7A (Dectin-1) signaling Reactome R-HSA-5607764
C-type lectin receptors (CLRs) Reactome R-HSA-5621481
CLEC7A/inflammasome pathway Reactome R-HSA-5660668
Regulation of necroptotic cell death Reactome R-HSA-5675482
Dimerization of procaspase-8 Reactome R-HSA-69416
Death Receptor Signaling Reactome R-HSA-73887
Activation, myristolyation of BID and translocation to mitochondria Reactome R-HSA-75108
Apoptotic execution phase Reactome R-HSA-75153
FasL/ CD95L signaling Reactome R-HSA-75157
TRAIL signaling Reactome R-HSA-75158
TNF signaling Reactome R-HSA-75893
TLR3-mediated TICAM1-dependent programmed cell death Reactome R-HSA-9013957
Interleukin-1 signaling Reactome R-HSA-9020702
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 Reactome R-HSA-933543
TRIF(TICAM1)-mediated TLR4 signaling Reactome R-HSA-937061
Diseases of programmed cell death Reactome R-HSA-9645723
Microbial modulation of RIPK1-mediated regulated necrosis Reactome R-HSA-9686347
Defective RIPK1-mediated regulated necrosis Reactome R-HSA-9693928
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation Reactome R-HSA-975138
MyD88 dependent cascade initiated on endosome Reactome R-HSA-975155
Regulation of NF-kappa B signaling Reactome R-HSA-9758274
MyD88 cascade initiated on plasma membrane Reactome R-HSA-975871
Nucleotide-binding oligomerization domain (NOD) pathway (WP1433) WikiPathways WP1433_r122867
Network map of SARS-CoV-2 signaling pathway (WP5115) WikiPathways WP5115_r124648
Integrated cancer pathway (WP1971) WikiPathways WP1971_r117762
16p11.2 proximal deletion syndrome (WP4949) WikiPathways WP4949_r115778
Alzheimer's disease (WP5124) WikiPathways WP5124_r123917
Measles virus infection (WP4630) WikiPathways WP4630_r123414
Hepatitis B infection (WP4666) WikiPathways WP4666_r123495
Nanomaterial induced apoptosis (WP2507) WikiPathways WP2507_r123897
Complement system in neuronal development and plasticity (WP5090) WikiPathways WP5090_r118898
Apoptosis modulation by HSP70 (WP384) WikiPathways WP384_r121706
Alzheimer's disease and miRNA effects (WP2059) WikiPathways WP2059_r119468
miRNA regulation of p53 pathway in prostate cancer (WP3982) WikiPathways WP3982_r108115
SARS-CoV-2 innate immunity evasion and cell-specific immune response (WP5039) WikiPathways WP5039_r124653
IL-18 signaling pathway (WP4754) WikiPathways WP4754_r115147
Acute viral myocarditis (WP4298) WikiPathways WP4298_r123508
Toll-like receptor signaling pathway (WP75) WikiPathways WP75_r119233
Fas ligand pathway and stress induction of heat shock proteins (WP314) WikiPathways WP314_r121827
Allograft rejection (WP2328) WikiPathways WP2328_r120805
Small cell lung cancer (WP4658) WikiPathways WP4658_r124606
Host-pathogen interaction of human coronaviruses - apoptosis (WP4864) WikiPathways WP4864_r124634
DNA damage response (WP707) WikiPathways WP707_r124174
Apoptosis (WP254) WikiPathways WP254_r118382
Pro-survival signaling of neuroprotectin D1 (WP5182) WikiPathways WP5182_r122168
Nonalcoholic fatty liver disease (WP4396) WikiPathways WP4396_r123350
Head and neck squamous cell carcinoma (WP4674) WikiPathways WP4674_r123494
TNF-related weak inducer of apoptosis (TWEAK) signaling pathway (WP2036) WikiPathways WP2036_r120940
Cytosolic DNA-sensing pathway (WP4655) WikiPathways WP4655_r123496
TNF-alpha signaling pathway (WP231) WikiPathways WP231_r124583
Apoptosis modulation and signaling (WP1772) WikiPathways WP1772_r120736
Non-small cell lung cancer (WP4255) WikiPathways WP4255_r123348
Regucalcin in proximal tubule epithelial kidney cells (WP4838) WikiPathways WP4838_r110282
Nanoparticle triggered regulated necrosis (WP2513) WikiPathways WP2513_r119820
AGE/RAGE pathway (WP2324) WikiPathways WP2324_r120674
miRNA regulation of DNA damage response (WP1530) WikiPathways WP1530_r124175
Parkin-ubiquitin proteasomal system pathway (WP2359) WikiPathways WP2359_r123101
Novel intracellular components of RIG-I-like receptor pathway (WP3865) WikiPathways WP3865_r123636
Transcripts
Accession Version MolecularType Name NCBI Comments
NR_174598 1 miscRNA transcript variant 61 NC_000002 Reference
NR_174588 1 miscRNA transcript variant 51 NC_000002 Reference
NR_174583 1 miscRNA transcript variant 47 NC_000002 Reference
NR_174590 1 miscRNA transcript variant 53 NC_000002 Reference
NR_174581 1 miscRNA transcript variant 46 NC_000002 Reference
NR_174594 1 miscRNA transcript variant 57 NC_000002 Reference
NR_174565 1 miscRNA transcript variant 44 NC_000002 Reference
NR_174582 1 miscRNA transcript variant 45 NC_000002 Reference
NR_111983 2 miscRNA transcript variant 8 NC_000002 Reference
NR_174600 1 miscRNA transcript variant 65 NC_000002 Reference
NR_174584 1 miscRNA transcript variant 48 NC_000002 Reference
NR_174592 1 miscRNA transcript variant 55 NC_000002 Reference
NR_174593 1 miscRNA transcript variant 56 NC_000002 Reference
NR_174585 1 miscRNA transcript variant 49 NC_000002 Reference
NR_174591 1 miscRNA transcript variant 54 NC_000002 Reference
NR_174601 1 miscRNA transcript variant 66 NC_000002 Reference
NR_174586 1 miscRNA transcript variant 50 NC_000002 Reference
XR_007082538 1 miscRNA transcript variant X5 NC_000002 Reference
NR_174595 1 miscRNA transcript variant 58 NC_000002 Reference
NR_174602 1 miscRNA transcript variant 67 NC_000002 Reference
NR_174596 1 miscRNA transcript variant 59 NC_000002 Reference
NR_174599 1 miscRNA transcript variant 62 NC_000002 Reference
NR_174564 1 miscRNA transcript variant 43 NC_000002 Reference
NR_174589 1 miscRNA transcript variant 52 NC_000002 Reference
XR_007082539 1 miscRNA transcript variant X6 NC_000002 Reference
NM_001228 5 mRNA transcript variant 1 NC_000002 Reference
NM_001400651 1 mRNA transcript variant 13 NC_000002 Reference
NM_001400663 1 mRNA transcript variant 24 NC_000002 Reference
NM_001400657 1 mRNA transcript variant 18 NC_000002 Reference
NM_001400660 1 mRNA transcript variant 21 NC_000002 Reference
NM_001400677 1 mRNA transcript variant 38 NC_000002 Reference
NM_001400669 1 mRNA transcript variant 30 NC_000002 Reference
NM_001400648 1 mRNA transcript variant 12 NC_000002 Reference
NM_001400680 1 mRNA transcript variant 41 NC_000002 Reference
NM_001080124 2 mRNA transcript variant 6 NC_000002 Reference
NM_033355 4 mRNA transcript variant 2 NC_000002 Reference
NM_001400661 1 mRNA transcript variant 22 NC_000002 Reference
NM_001400679 1 mRNA transcript variant 40 NC_000002 Reference
XM_047445961 1 mRNA transcript variant X7 NC_000002 Reference
XM_047445959 1 mRNA transcript variant X1 NC_000002 Reference
NM_001080125 2 mRNA transcript variant 7 NC_000002 Reference
NM_001400642 1 mRNA transcript variant 10 NC_000002 Reference
NM_001400665 1 mRNA transcript variant 26 NC_000002 Reference
NM_001400655 1 mRNA transcript variant 16 NC_000002 Reference
NM_001400750 1 mRNA transcript variant 63 NC_000002 Reference
NM_001400662 1 mRNA transcript variant 23 NC_000002 Reference
NM_001400751 1 mRNA transcript variant 64 NC_000002 Reference
NM_001400645 1 mRNA transcript variant 11 NC_000002 Reference
NM_001400656 1 mRNA transcript variant 17 NC_000002 Reference
NM_001400658 1 mRNA transcript variant 19 NC_000002 Reference
NM_001400678 1 mRNA transcript variant 39 NC_000002 Reference
NM_001400668 1 mRNA transcript variant 29 NC_000002 Reference
NM_001400654 1 mRNA transcript variant 15 NC_000002 Reference
XM_005246893 4 mRNA transcript variant X4 NC_000002 Reference
XM_047445960 1 mRNA transcript variant X2 NC_000002 Reference
NM_001400674 1 mRNA transcript variant 35 NC_000002 Reference
NM_001372051 1 mRNA transcript variant 9 NC_000002 Reference
NM_001400670 1 mRNA transcript variant 31 NC_000002 Reference
NM_001400671 1 mRNA transcript variant 32 NC_000002 Reference
NM_001400666 1 mRNA transcript variant 27 NC_000002 Reference
NM_001400664 1 mRNA transcript variant 25 NC_000002 Reference
NM_033356 4 mRNA transcript variant 3 NC_000002 Reference
NM_001400676 1 mRNA transcript variant 37 NC_000002 Reference
NM_001400667 1 mRNA transcript variant 28 NC_000002 Reference
NM_001400653 1 mRNA transcript variant 14 NC_000002 Reference
NM_001400673 1 mRNA transcript variant 34 NC_000002 Reference
NM_001400659 1 mRNA transcript variant 20 NC_000002 Reference
NM_001400672 1 mRNA transcript variant 33 NC_000002 Reference
NM_001400675 1 mRNA transcript variant 36 NC_000002 Reference
XM_011511969 3 mRNA transcript variant X3 NC_000002 Reference