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CASP9

caspase 9
General Information
Name caspase 9
Alias
  • caspase-9
  • ICE-like apoptotic protease 6
  • apoptotic protease MCH-6
  • apoptotic protease activating factor 3
  • caspase 9, apoptosis-related cysteine peptidase
  • protein phosphatase 1, regulatory subunit 56
Gene_family Caspases|Apoptosome|Caspase recruitment domain containing|Protein phosphatase 1 regulatory subunits
organism Homo sapiens
entrez_id 842
location 1p36.21
transcript_count 9
exon_count 11
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
    Stringdb Caspase-9; Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf- 1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP- ribose) polymerase (PARP); Apoptosome
    nextProt Lacks activity is an dominant-negative inhibitor of caspase-9.
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
CASP9 BioGRID APAF1 GeneID BioGRID Affinity Capture-Western; Co-fractionation; Reconstituted Complex; Two-hybrid
CASP9 BioGRID BCL2L10 GeneID BioGRID Affinity Capture-Western
CASP9 BioGRID CALCOCO2 GeneID BioGRID Proximity Label-MS
CASP9 BioGRID BIRC8 GeneID BioGRID Affinity Capture-MS; Reconstituted Complex; Two-hybrid
CASP9 BioGRID SLFN11 GeneID BioGRID Affinity Capture-MS
CASP9 BioGRID HTRA4 GeneID BioGRID Affinity Capture-Western
CASP9 BioGRID HNRNPH1 GeneID BioGRID Affinity Capture-RNA
CASP9 BioGRID TRIM72 GeneID BioGRID Affinity Capture-MS
CASP9 BioGRID HSP90AB2P GeneID BioGRID Affinity Capture-MS
CASP9 BioGRID HMGB1P1 GeneID BioGRID Affinity Capture-MS
CASP9 BioGRID ACTR3 GeneID BioGRID Affinity Capture-MS
CASP9 BioGRID AKAP12 GeneID BioGRID Affinity Capture-MS
CASP9 BioGRID RNPEP GeneID BioGRID Affinity Capture-MS
CASP9 BioGRID P4HB GeneID BioGRID Affinity Capture-MS
CASP9 BioGRID HSPB1 GeneID BioGRID Affinity Capture-MS
CASP9 BioGRID HPRT1 GeneID BioGRID Affinity Capture-MS
CASP9 BioGRID HMGB1 GeneID BioGRID Affinity Capture-MS
CASP9 BioGRID EIF4A1 GeneID BioGRID Affinity Capture-MS
CASP9 BioGRID CFL1 GeneID BioGRID Affinity Capture-MS
CASP9 BioGRID CASP9 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
CASP9 BioGRID ATG7 GeneID BioGRID Affinity Capture-Western
CASP9 BioGRID BIRC7 GeneID BioGRID Affinity Capture-Western; Two-hybrid
CASP9 BioGRID XIAP GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Co-crystal Structure; Co-localization; FRET; Far Western; Protein-peptide; Reconstituted Complex; Two-hybrid
CASP9 BioGRID BIRC2 GeneID BioGRID Affinity Capture-Western; Co-crystal Structure; Co-localization; Protein-peptide; Reconstituted Complex; Two-hybrid
CASP9 BioGRID GMEB1 GeneID BioGRID Affinity Capture-Western
CASP9 BioGRID BICD2 GeneID BioGRID Proximity Label-MS
CASP9 BioGRID HIP1 GeneID BioGRID Affinity Capture-Western
CASP9 BioGRID HECTD3 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
CASP9 BioGRID ARNT GeneID BioGRID Biochemical Activity; Reconstituted Complex
CASP9 BioGRID CYCS GeneID BioGRID Co-localization
CASP9 BioGRID CASP3 GeneID BioGRID Biochemical Activity; Co-localization
CASP9 BioGRID BCL2L1 GeneID BioGRID Affinity Capture-Western; Co-localization
CASP9 BioGRID BIRC5 GeneID BioGRID Affinity Capture-Western; Co-localization
CASP9 BioGRID BIRC3 GeneID BioGRID Affinity Capture-Western; Co-localization; Reconstituted Complex; Two-hybrid
CASP9 BioGRID CASP12 GeneID BioGRID Biochemical Activity
CASP9 BioGRID RNF34 GeneID BioGRID Affinity Capture-Western
CASP9 BioGRID BAX GeneID BioGRID Co-fractionation
CASP9 BioGRID ABL1 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
CASP9 BioGRID PTCH1 GeneID BioGRID Affinity Capture-Western
CASP9 BioGRID CRYAB GeneID BioGRID Affinity Capture-Western
CASP9 BioGRID SQSTM1 GeneID BioGRID Affinity Capture-Western
CASP9 BioGRID JUN GeneID BioGRID Biochemical Activity
CASP9 BioGRID CASP7 GeneID BioGRID Biochemical Activity
CASP9 BioGRID BRCA1 GeneID BioGRID Affinity Capture-Western
CASP9 BioGRID RB1 GeneID BioGRID Biochemical Activity
CASP9 BioGRID MSTO1 GeneID BioGRID Two-hybrid
CASP9 BioGRID HSD17B4 GeneID BioGRID Two-hybrid
CASP9 BioGRID VCP GeneID BioGRID Affinity Capture-Western
CASP9 BioGRID BIRC6 GeneID BioGRID Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
CASP9 BioGRID RNF2 GeneID BioGRID Biochemical Activity
CASP9 Protein MZB1 GeneID HPRD
CASP9 Protein CARD8 GeneID HPRD
CASP9 Protein GMEB1 GeneID HPRD
CASP9 Protein BIRC8 GeneID HPRD
CASP9 Protein NAIP GeneID HPRD
CASP9 Protein NLRP1 GeneID HPRD
CASP9 Protein NOD1 GeneID HPRD
CASP9 Protein BIRC7 GeneID HPRD
CASP9 Protein BIRC6 GeneID HPRD
CASP9 Protein DIABLO GeneID HPRD
CASP9 Protein BCL10 GeneID HPRD
CASP9 Protein BIRC5 GeneID HPRD
CASP9 Protein ILK GeneID HPRD
CASP9 Protein CASP9 GeneID HPRD
CASP9 Protein APAF1 GeneID HPRD
CASP9 Protein MAPK3 GeneID HPRD
CASP9 Protein HIP1 GeneID HPRD
CASP9 Protein CASP10 GeneID HPRD
CASP9 Protein BIRC2 GeneID HPRD
CASP9 Protein BIRC3 GeneID HPRD
CASP9 Protein MAP2K2 GeneID HPRD
CASP9 Protein CASP3 GeneID HPRD
CASP9 Protein SRF GeneID HPRD
CASP9 Protein BCL2L1 GeneID HPRD
CASP9 Protein XIAP GeneID HPRD
CASP9 Protein VIM GeneID HPRD
CASP9 Protein ABL1 GeneID HPRD
CASP9 Protein RB1 GeneID HPRD
CASP9 Protein PRKCZ GeneID HPRD
CASP9 Protein MAPK1 GeneID HPRD
CASP9 Protein MAP2K1 GeneID HPRD
CASP9 Protein LYN GeneID HPRD
CASP9 Protein AKT1 GeneID HPRD
CASP9 Protein DSP GeneID HPRD
CASP9 Protein CYCS GeneID HPRD
CASP9 Protein GZMB GeneID HPRD
CASP9 Protein DCC GeneID HPRD
CASP9 Protein HSPD1 GeneID HPRD
CASP9 Protein CAPN2 GeneID HPRD
CASP9 BioGRID CASP10 GeneID BioGRID Biochemical Activity
CASP9 BioGRID CASP8 GeneID BioGRID Biochemical Activity; Phenotypic Suppression
CASP9 BioGRID CASP2 GeneID BioGRID Phenotypic Suppression
CASP9 BioGRID NLRP1 GeneID BioGRID Affinity Capture-Western
CASP9 BioGRID NOD1 GeneID BioGRID Affinity Capture-Western
CASP9 BioGRID DCC GeneID BioGRID Affinity Capture-Western
CASP9 BioGRID MAPK1 GeneID BioGRID Biochemical Activity
CASP9 BioGRID NAIP GeneID BioGRID Far Western
CASP9 Protein RB1 GeneID BIND CASP9 (caspase-9) cleaves RB-1 (hRB) at the LEND consensus site to produce the p76 form.
CASP9 Protein XIAP GeneID BIND XIAP interacts with and ubiquitinates Caspase-9.
CASP9 Protein BIRC6 GeneID BIND Apollon interacts with and ubiquitinates Caspase-9.
CASP9 None None None BIND BRUCE interacts with Casp-9. This interaction was modeled on a demonstrated interaction between mouse BRUCE and human Casp-9.
CASP9 Protein NOD1 GeneID BIND Nod1 interacts with and regulates Caspase-9
CASP9 Protein APAF1 GeneID BIND APAF1 interacts with CASP9.
CASP9 Protein APAF1 GeneID BIND APAF1 interacts with CASP9.
StringDB
A B experiments database textmining combined score hadb nhadb
CASP9 SP1 0 0 243 254 1 2
CASP9 IL1B 0 0 603 618 1 2
CASP9 POTEM 0 0 0 155 1 1
CASP9 BAG3 0 0 212 225 1 2
CASP9 PRKCB 0 0 224 224 1 2
CASP9 CYP27B1 0 0 273 273 1 1
CASP9 EDN1 0 0 231 236 1 1
CASP9 MT1E 0 0 147 164 1 1
CASP9 HIF1A 0 0 520 523 1 2
CASP9 TRAF5 0 0 213 214 1 1
CASP9 SIRT5 0 0 210 210 1 1
CASP9 GCK 0 0 108 193 1 1
CASP9 NEDD4 0 0 134 183 1 2
CASP9 ASAP1 0 0 0 163 1 1
CASP9 KLK3 0 0 262 262 1 1
CASP9 CTSL 0 0 152 167 1 2
CASP9 LATS2 0 0 162 161 1 1
CASP9 CXCL8 0 0 467 467 1 2
CASP9 MFN2 0 0 391 414 1 2
CASP9 ACTRT3 0 0 0 155 1 1
CASP9 APP 0 0 361 362 1 2
CASP9 EGR1 0 0 252 263 1 2
CASP9 EPHA2 0 0 134 153 1 1
CASP9 TRPV1 0 0 229 230 1 2
CASP9 CTNNB1 0 0 563 612 1 2
CASP9 MAP1LC3A 0 0 468 531 1 2
CASP9 HRAS 0 0 456 503 1 2
CASP9 CDK2 0 0 634 671 1 2
CASP9 RBM5 0 0 214 219 1 1
CASP9 TNFRSF1B 0 0 305 314 1 1
CASP9 DNM3 0 0 0 170 1 1
CASP9 XPO1 0 0 210 210 1 1
CASP9 RHO 0 0 123 161 1 2
CASP9 WNT2B 0 0 107 243 1 1
CASP9 MYOM2 0 0 170 169 1 1
CASP9 NOTCH1 0 0 394 404 1 2
CASP9 PTPN13 0 0 233 232 1 1
CASP9 MMP1 0 0 257 288 1 1
CASP9 ARAF 0 0 181 199 1 1
CASP9 CD40LG 0 0 236 247 1 1
CASP9 PTGS1 0 0 193 198 1 1
CASP9 TRAF4 0 0 181 182 1 1
CASP9 PIDD1 0 0 504 585 1 1
CASP9 FGF13 0 0 193 193 1 1
CASP9 CTAG1A 0 0 155 154 1 1
CASP9 CXCR4 0 0 297 307 1 2
CASP9 HIST1H4F 0 0 216 216 1 1
CASP9 ANXA11 0 0 64 379 1 1
CASP9 E2F2 0 0 181 188 1 1
CASP9 POTEF 0 0 217 454 1 1
CASP9 PSMC6 0 0 260 260 1 1
CASP9 CALM1 0 0 138 212 1 1
CASP9 MTOR 0 0 595 601 1 2
CASP9 NLRP1 486 0 330 640 1 1
CASP9 RAD51 0 0 193 194 1 2
CASP9 CTRL 0 0 391 390 1 2
CASP9 SCAF11 0 0 503 503 1 1
CASP9 DCXR 0 0 207 207 1 1
CASP9 IL6 0 0 602 624 1 2
CASP9 UCP2 0 0 237 255 1 2
CASP9 IL3RA 0 0 181 198 1 1
CASP9 MPO 0 0 287 309 1 2
CASP9 ACAN 0 0 182 181 1 1
CASP9 PIK3C3 0 0 324 335 1 2
CASP9 GZMB 213 0 459 556 1 1
CASP9 RPS6 0 0 187 187 1 2
CASP9 TNFRSF1A 0 0 654 654 1 1
CASP9 MYOG 0 0 134 152 1 1
CASP9 E2F6 0 0 155 162 1 1
CASP9 PLEK 0 0 290 290 1 1
CASP9 OCLN 0 0 261 261 1 1
CASP9 STAT1 0 0 391 401 1 2
CASP9 RNASE1 0 0 263 263 1 1
CASP9 ENDOG 0 0 706 735 1 1
CASP9 ELAVL3 0 0 140 174 1 1
CASP9 BCL2L2-PABPN1 0 0 637 701 1 1
CASP9 FOXO6 0 0 143 161 1 1
CASP9 TCFL5 0 0 136 173 1 1
CASP9 HSPA1L 0 0 0 230 1 1
CASP9 PPID 0 0 190 258 1 1
CASP9 CREBBP 0 0 151 170 1 1
CASP9 POMP 0 0 0 258 1 1
CASP9 RECK 0 0 150 168 1 1
CASP9 TMOD2 0 0 0 159 1 1
CASP9 SDHB 0 0 172 171 1 1
CASP9 HAVCR1 0 0 170 169 1 1
CASP9 ACO2 0 0 205 235 1 1
CASP9 KCNJ11 0 0 535 535 1 1
CASP9 USP9X 0 0 187 211 1 1
CASP9 CCL5 0 0 234 234 1 2
CASP9 CREB1 0 0 460 471 1 2
CASP9 CIDEC 0 0 74 234 1 1
CASP9 GSDMD 0 0 325 438 1 2
CASP9 NOX3 0 0 124 169 1 1
CASP9 KHDRBS1 0 0 195 229 1 1
CASP9 IFNG 0 0 321 378 1 2
CASP9 BIRC2 887 900 774 997 1 1
CASP9 TUBB1 0 0 0 161 1 1
CASP9 HIST2H2AC 0 0 155 154 1 1
CASP9 HSPB6 0 0 162 182 1 1
CASP9 SLC25A6 0 0 125 237 1 1
CASP9 FOXM1 0 0 212 226 1 1
CASP9 FBXO32 0 0 195 195 1 2
CASP9 LAMTOR5 0 0 560 560 1 1
CASP9 MGMT 0 0 231 230 1 2
CASP9 HSPD1 213 0 218 398 1 1
CASP9 PERP 0 0 242 294 1 1
CASP9 CS 0 0 142 161 1 1
CASP9 ANXA5 0 0 866 879 1 2
CASP9 CCNB1 0 0 773 809 1 1
CASP9 PDE11A 0 0 0 206 1 1
CASP9 PLK1 0 0 323 323 1 2
CASP9 HSF1 0 0 90 153 1 2
CASP9 PRDX6 0 0 128 165 1 1
CASP9 EPO 0 0 322 352 1 2
CASP9 TNFSF9 0 0 158 157 1 1
CASP9 CXCL13 0 0 167 167 1 1
CASP9 GSDMA 0 0 206 257 1 1
CASP9 DIAPH1 0 0 357 357 1 1
CASP9 SIRT2 0 0 242 241 1 2
CASP9 PHEX 0 0 350 349 1 1
CASP9 PRDX5 0 0 90 156 1 1
CASP9 TLR10 0 0 60 151 1 1
CASP9 MMP20 0 0 0 206 1 1
CASP9 ZAP70 0 0 144 388 1 1
CASP9 STAT4 0 0 57 228 1 1
CASP9 CASP6 0 900 803 922 1 1
CASP9 PHLPP1 0 0 143 158 1 2
CASP9 KITLG 0 0 166 165 1 1
CASP9 CLDN15 0 0 123 163 1 1
CASP9 PIK3R4 0 0 173 173 1 2
CASP9 RELA 0 0 393 406 1 2
CASP9 ENSG00000026036 0 0 204 204 1 1
CASP9 BCL2L1 678 0 870 973 1 2
CASP9 TUBB4A 0 0 205 304 1 1
CASP9 KLF6 0 0 155 168 1 1
CASP9 EVPL 0 0 134 212 1 1
CASP9 DNMT3A 0 0 181 181 1 2
CASP9 NFKB1 0 0 310 360 1 2
CASP9 DNMT3B 0 0 181 181 1 1
CASP9 CYP1A1 0 0 261 261 1 2
CASP9 ATG14 0 0 210 243 1 2
CASP9 TNFRSF25 0 0 424 434 1 1
CASP9 GAPDH 0 0 731 750 1 2
CASP9 TRIAP1 0 0 161 161 1 1
CASP9 TLR4 0 0 450 478 1 2
CASP9 SMAD2 0 0 319 319 1 2
CASP9 CD22 0 0 181 181 1 1
CASP9 ABL1 270 0 695 773 1 1
CASP9 HIST4H4 0 0 216 216 1 1
CASP9 PTBP1 0 900 108 906 1 2
CASP9 NOS2 0 0 275 280 1 2
CASP9 MAP2K7 0 0 520 532 1 1
CASP9 TNFAIP8L1 0 0 50 481 1 1
CASP9 POTEE 0 0 0 332 1 1
CASP9 GABARAPL2 0 0 276 305 1 2
CASP9 LGMN 0 0 120 154 1 1
CASP9 PARK2 0 0 266 275 1 1
CASP9 CCNH 0 0 125 156 1 1
CASP9 IFNA1 0 0 310 309 1 1
CASP9 IL18 0 0 392 400 1 2
CASP9 ILK 270 0 219 435 1 1
CASP9 WNT5A 0 0 171 226 1 2
CASP9 PPIG 0 0 185 216 1 1
CASP9 APEX1 0 0 195 195 1 1
CASP9 IL1R1 0 0 182 181 1 1
CASP9 MYC 0 0 617 649 1 2
CASP9 IL15 0 0 295 310 1 1
CASP9 PPARGC1A 0 0 296 311 1 2
CASP9 TNFRSF6B 0 0 204 204 1 1
CASP9 H1F0 0 0 270 270 1 1
CASP9 ENSG00000279576 0 0 181 181 1 1
CASP9 PI3 0 0 282 282 1 2
CASP9 IGF1R 0 0 450 462 1 2
CASP9 SDHC 0 0 293 294 1 1
CASP9 TUBA3E 0 0 0 161 1 1
CASP9 DVL1 0 0 144 151 1 1
CASP9 CASP8AP2 0 0 134 158 1 1
CASP9 UNC5A 0 650 112 676 1 1
CASP9 ADORA1 0 0 155 168 1 1
CASP9 PIK3R3 0 0 140 174 1 1
CASP9 G6PC 0 0 113 153 1 1
CASP9 MEFV 0 0 325 325 1 1
CASP9 APPL1 0 800 62 835 1 1
CASP9 FKBP1B 0 0 54 337 1 1
CASP9 RICTOR 0 0 261 266 1 2
CASP9 ANXA9 0 0 57 374 1 1
CASP9 MAP2 0 0 154 153 1 2
CASP9 TAB1 0 0 212 212 1 1
CASP9 GLS 0 0 326 325 1 2
CASP9 TRAF2 0 0 392 487 1 2
CASP9 MX1 0 0 140 224 1 1
CASP9 P4HB 117 0 241 379 1 2
CASP9 GPX7 0 0 46 466 1 1
CASP9 TMBIM6 0 0 202 207 1 1
CASP9 TUBA3D 0 0 0 161 1 1
CASP9 MMP17 0 0 0 207 1 1
CASP9 CEACAM5 0 0 210 210 1 1
CASP9 TOP1 0 0 404 442 1 1
CASP9 PIK3CA 0 0 319 343 1 2
CASP9 MAU2 0 0 234 234 1 1
CASP9 ALOX12 0 0 167 167 1 1
CASP9 ST20 0 0 0 200 1 1
CASP9 GPR78 0 0 234 245 1 1
CASP9 ANP32A 0 0 203 203 1 1
CASP9 HIST1H4L 0 0 216 216 1 1
CASP9 SMAD4 0 0 260 260 1 2
CASP9 MYCN 0 0 275 275 1 1
CASP9 NOL3 0 0 244 255 1 1
CASP9 BLID 0 0 442 442 1 1
CASP9 MOAP1 0 0 175 175 1 1
CASP9 ACTA1 0 0 71 215 1 1
CASP9 PARK7 0 0 248 248 1 2
CASP9 CASP10 270 0 734 479 1 1
CASP9 FHL2 0 0 439 439 1 1
CASP9 AKT2 0 900 395 941 1 2
CASP9 CIDEA 0 0 122 201 1 1
CASP9 UBE2K 0 0 166 198 1 1
CASP9 PGAM5 0 0 248 248 1 1
CASP9 TLR1 0 0 97 179 1 1
CASP9 NFE2L2 0 0 457 457 1 2
CASP9 RB1CC1 0 0 203 203 1 2
CASP9 MFF 0 0 320 319 1 1
CASP9 ODC1 0 0 240 239 1 1
CASP9 VASP 0 0 66 227 1 1
CASP9 MAP2K1 213 0 469 579 1 1
CASP9 OPA1 0 0 150 215 1 2
CASP9 CDKN2D 0 0 115 160 1 1
CASP9 PPIF 0 0 469 495 1 1
CASP9 BRCA1 270 0 341 507 1 2
CASP9 CD80 0 0 195 208 1 2
CASP9 STK11 0 0 240 239 1 2
CASP9 DSP 213 0 70 306 1 1
CASP9 CFTR 0 0 95 190 1 2
CASP9 BNIP2 0 0 150 208 1 1
CASP9 PRKCE 0 0 127 152 1 1
CASP9 LCN2 0 0 134 157 1 1
CASP9 TP53 0 0 834 862 1 2
CASP9 PSCA 0 0 171 171 1 1
CASP9 MDM2 0 0 607 639 1 2
CASP9 TUBA4A 0 0 43 177 1 1
CASP9 ALOX15 0 0 144 163 1 1
CASP9 MAP3K13 0 0 193 248 1 1
CASP9 ATP2C1 0 0 240 272 1 1
CASP9 EGFR 0 0 601 623 1 2
CASP9 CFLAR 0 0 710 342 1 2
CASP9 CDK4 0 0 620 635 1 2
CASP9 HIST1H4I 0 0 216 216 1 1
CASP9 ENSG00000278522 0 0 0 155 1 1
CASP9 HTT 0 0 329 358 1 2
CASP9 MYD88 0 0 354 438 1 2
CASP9 ADORA3 0 0 147 160 1 1
CASP9 TNFRSF4 0 0 260 260 1 1
CASP9 SARM1 0 0 124 301 1 1
CASP9 FADD 0 0 801 869 1 2
CASP9 UCHL5 0 0 209 209 1 1
CASP9 LAMP1 0 0 259 259 1 2
CASP9 SLC2A1 0 0 261 261 1 2
CASP9 NEDD8 0 0 123 175 1 2
CASP9 FGF7 0 0 124 160 1 1
CASP9 CARD9 0 0 124 218 1 1
CASP9 ACTRT1 0 0 0 155 1 1
CASP9 HK2 0 0 217 302 1 2
CASP9 TRAF1 0 0 325 371 1 1
CASP9 CSF3 0 0 228 227 1 1
CASP9 IRAK1 0 0 181 235 1 1
CASP9 LMNA 0 0 361 385 1 2
CASP9 RAF1 0 0 425 438 1 2
CASP9 EDA 0 0 52 221 1 1
CASP9 MAP1A 0 0 324 375 1 2
CASP9 ZBP1 0 0 132 167 1 1
CASP9 SLC25A4 0 0 134 223 1 1
CASP9 CRADD 0 0 638 651 1 1
CASP9 TNFRSF11B 0 0 260 260 1 1
CASP9 MAP3K7 0 0 153 172 1 2
CASP9 HDAC2 0 0 261 274 1 1
CASP9 DDIT3 0 0 611 626 1 2
CASP9 MPPED2 0 0 62 174 1 1
CASP9 WNT4 0 0 96 207 1 1
CASP9 CDON 0 0 73 209 1 1
CASP9 HDAC6 0 0 323 323 1 2
CASP9 APAF1 981 900 990 999 1 2
CASP9 CDH2 0 0 418 418 1 1
CASP9 PDCD6 0 0 127 305 1 1
CASP9 ZBTB10 0 0 91 166 1 1
CASP9 JAK2 0 0 421 455 1 2
CASP9 HSPA12B 0 0 74 217 1 1
CASP9 NR4A1 0 0 204 204 1 2
CASP9 PPARD 0 0 94 174 1 1
CASP9 PSMD10 0 0 93 360 1 1
CASP9 SH3BP5 0 0 103 164 1 1
CASP9 BRD4 0 0 122 157 1 2
CASP9 ACTL7B 0 0 0 155 1 1
CASP9 CALM3 0 0 137 192 1 1
CASP9 CLU 0 0 162 161 1 2
CASP9 CYBA 0 0 155 175 1 1
CASP9 SRSF1 0 0 294 294 1 1
CASP9 MMP15 0 0 0 205 1 1
CASP9 UACA 0 600 442 779 1 1
CASP9 TAOK2 0 0 292 292 1 1
CASP9 MYH6 0 0 194 220 1 1
CASP9 GCLM 0 0 184 209 1 1
CASP9 XRCC6 0 0 284 284 1 1
CASP9 ERN1 0 0 562 572 1 2
CASP9 STAT3 0 0 603 636 1 2
CASP9 POTEG 0 0 0 155 1 1
CASP9 GDNF 0 0 260 260 1 2
CASP9 EZH2 0 0 265 276 1 2
CASP9 VDAC2 0 0 294 369 1 1
CASP9 HTRA1 0 0 123 172 1 1
CASP9 EIF4G3 0 900 0 901 1 1
CASP9 AGO2 0 0 181 181 1 2
CASP9 SDHA 0 0 155 154 1 1
CASP9 CCL2 0 0 378 383 1 2
CASP9 ALB 0 0 606 672 1 2
CASP9 CD68 0 0 195 195 1 2
CASP9 CASP8 488 0 915 636 1 2
CASP9 CARD17 0 0 218 337 1 1
CASP9 EIF4A1 117 900 74 912 1 1
CASP9 CD276 0 0 155 154 1 1
CASP9 SNAI2 0 0 416 428 1 1
CASP9 BAG2 0 0 140 161 1 1
CASP9 CUL1 0 0 141 178 1 1
CASP9 POTED 0 0 0 155 1 1
CASP9 CASP7 271 900 870 943 1 1
CASP9 ELAVL1 0 0 183 183 1 2
CASP9 DUSP7 0 0 45 192 1 1
CASP9 ITGB1 0 0 212 222 1 1
CASP9 ANXA3 0 0 62 556 1 1
CASP9 PGK1 0 0 87 179 1 2
CASP9 TNFAIP8L2 0 0 211 275 1 1
CASP9 NOTCH3 0 0 139 153 1 1
CASP9 IL4 0 0 310 309 1 1
CASP9 CSNK2A2 0 0 150 181 1 1
CASP9 PDGFRB 0 0 194 194 1 2
CASP9 TECR 0 0 205 205 1 1
CASP9 NUMB 0 0 123 180 1 1
CASP9 EP300 0 0 247 246 1 2
CASP9 GPX5 0 0 0 370 1 1
CASP9 CDK5 0 0 261 266 1 2
CASP9 PTBP2 0 900 48 900 1 1
CASP9 TNFRSF10A 0 0 705 741 1 1
CASP9 TUBB3 0 0 134 261 1 1
CASP9 ERO1L 0 0 242 241 1 1
CASP9 ROCK1 0 0 335 359 1 2
CASP9 SNCAIP 0 0 108 153 1 2
CASP9 TP53AIP1 0 0 260 260 1 1
CASP9 SMAD3 0 0 260 260 1 2
CASP9 ANXA8 0 0 638 638 1 1
CASP9 BIRC3 877 900 756 997 1 1
CASP9 SIRT6 0 0 214 214 1 2
CASP9 CTH 0 0 155 190 1 1
CASP9 DDX58 0 0 683 690 1 1
CASP9 AIM2 0 0 248 256 1 2
CASP9 AMD1 0 0 74 242 1 1
CASP9 HDAC8 0 0 166 165 1 1
CASP9 CDK6 0 0 520 554 1 2
CASP9 AGER 0 0 217 217 1 2
CASP9 HYOU1 0 0 112 203 1 1
CASP9 HIST1H4E 0 0 216 216 1 1
CASP9 CERS2 0 0 130 151 1 1
CASP9 ACTC1 0 0 57 210 1 1
CASP9 MAPKAPK2 0 0 229 228 1 1
CASP9 CDH1 0 0 517 547 1 2
CASP9 BCL2L10 0 0 698 748 1 1
CASP9 IDH1 0 0 128 160 1 1
CASP9 MFGE8 0 0 119 153 1 1
CASP9 CD33 0 0 181 181 1 1
CASP9 PRKCZ 213 0 194 353 1 1
CASP9 PLG 0 0 243 254 1 1
CASP9 BUB1B 0 0 166 165 1 1
CASP9 BCL2L13 0 0 212 212 1 2
CASP9 ZEB2 0 0 167 167 1 1
CASP9 LGALS4 0 0 150 165 1 1
CASP9 CLDN12 0 0 174 173 1 1
CASP9 MAP3K11 0 0 157 176 1 1
CASP9 MIEF2 0 0 150 168 1 1
CASP9 DPP4 0 0 150 180 1 1
CASP9 BSG 0 0 181 181 1 1
CASP9 BCHE 0 0 165 165 1 1
CASP9 ALK 0 0 170 189 1 2
CASP9 ABCA1 0 0 124 153 1 2
CASP9 ROCK2 0 0 134 195 1 1
CASP9 MRPS7 0 0 172 197 1 1
CASP9 TRADD 0 0 600 648 1 1
CASP9 WNT1 0 0 181 219 1 2
CASP9 CYP3A4 0 0 181 181 1 1
CASP9 DGCR14 0 0 218 218 1 1
CASP9 CCL4 0 0 150 173 1 1
CASP9 RHOB 0 0 150 184 1 1
CASP9 IL1A 0 0 260 260 1 1
CASP9 DNM2 0 0 89 244 1 1
CASP9 MAVS 0 0 243 272 1 2
CASP9 H2AFX 0 0 505 505 1 1
CASP9 ATP2A1 0 0 94 182 1 1
CASP9 ACTR1B 0 0 0 155 1 1
CASP9 CRYGC 0 0 306 306 1 1
CASP9 HSPA6 0 0 90 183 1 1
CASP9 DIABLO 213 900 939 995 1 2
CASP9 HIST2H3PS2 0 0 456 483 1 1
CASP9 PXN 0 0 202 208 1 1
CASP9 RPS5 0 0 0 164 1 1
CASP9 IFIH1 0 0 234 249 1 1
CASP9 SESN2 0 0 150 171 1 2
CASP9 INCENP 0 0 207 224 1 1
CASP9 TNS1 0 0 322 326 1 1
CASP9 MMP16 0 0 46 192 1 1
CASP9 IL1F10 0 0 0 153 1 1
CASP9 GPX4 0 0 217 454 1 2
CASP9 VR1 0 0 229 230 1 1
CASP9 ACAP3 0 0 0 163 1 1
CASP9 PRNP 0 0 74 176 1 2
CASP9 SRPK1 0 0 218 218 1 1
CASP9 NR3C1 0 0 205 220 1 1
CASP9 PRF1 0 0 323 323 1 1
CASP9 MX2 0 0 73 153 1 1
CASP9 FKBP1A 0 0 315 685 1 2
CASP9 CHKA 0 0 184 183 1 1
CASP9 CISH 0 0 170 169 1 1
CASP9 RCSD1 0 0 0 161 1 1
CASP9 P2RX7 0 0 154 164 1 2
CASP9 CTGF 0 0 246 245 1 1
CASP9 VIM 213 0 96 286 1 2
CASP9 MAGEA3 0 0 171 171 1 2
CASP9 SKP2 0 0 282 283 1 2
CASP9 GCLC 0 0 213 223 1 1
CASP9 ARG1 0 0 157 156 1 2
CASP9 MAPK8 0 0 601 609 1 2
CASP9 AURKB 0 0 337 342 1 1
CASP9 XRCC1 0 0 169 169 1 1
CASP9 ACAP2 0 0 0 163 1 1
CASP9 PTK2 0 0 342 346 1 2
CASP9 ADIPOQ 0 0 167 167 1 2
CASP9 MAP2K4 0 0 324 350 1 1
CASP9 PAK2 0 0 139 155 1 1
CASP9 API5 0 0 161 204 1 1
CASP9 MUT 0 0 241 448 1 1
CASP9 BRAF 0 0 128 179 1 2
CASP9 AKIP1 0 0 95 156 1 1
CASP9 APPL2 0 0 0 182 1 1
CASP9 TLR7 0 0 155 180 1 2
CASP9 IMMT 0 0 204 204 1 1
CASP9 MAPK9 0 0 391 413 1 2
CASP9 OGG1 0 0 233 232 1 1
CASP9 CYCS 680 900 990 999 1 2
CASP9 CHEK2 0 0 506 525 1 1
CASP9 GADD45B 0 0 255 254 1 1
CASP9 RPS6KA3 0 0 234 234 1 1
CASP9 TRAF6 0 0 294 305 1 2
CASP9 AIFM2 0 0 151 166 1 1
CASP9 ANXA13 0 0 55 570 1 1
CASP9 NANOG 0 0 295 295 1 2
CASP9 HK1 0 0 95 181 1 1
CASP9 ITPR1 0 0 321 321 1 2
CASP9 FASN 0 0 193 193 1 2
CASP9 PCSK1 0 0 325 339 1 1
CASP9 BFAR 0 0 134 184 1 1
CASP9 PAWR 0 0 243 242 1 1
CASP9 RGMA 0 0 0 167 1 1
CASP9 PRTN3 0 0 184 183 1 1
CASP9 EGF 0 0 503 504 1 2
CASP9 ATP5A1 0 0 115 235 1 1
CASP9 AKR1B1 0 0 211 225 1 1
CASP9 IL17A 0 0 261 261 1 2
CASP9 PLAU 0 0 187 187 1 1
CASP9 PROCR 0 0 109 164 1 1
CASP9 TYR 0 0 145 177 1 2
CASP9 POTEJ 0 0 0 332 1 1
CASP9 CDKN1C 0 0 166 166 1 1
CASP9 PIK3R1 0 0 234 265 1 1
CASP9 CLTC 0 0 441 441 1 1
CASP9 DICER1 0 0 240 376 1 1
CASP9 CYP1B1 0 0 167 167 1 1
CASP9 GATA4 0 0 137 172 1 2
CASP9 HSPA4 0 0 600 643 1 1
CASP9 MIEF1 0 0 210 215 1 1
CASP9 ACHE 0 0 245 244 1 2
CASP9 TEK 0 0 165 165 1 1
CASP9 RPAP2 0 0 45 192 1 1
CASP9 PPARA 0 0 295 308 1 2
CASP9 CCR2 0 0 143 166 1 2
CASP9 CYP2E1 0 0 325 325 1 2
CASP9 PDCD4 0 0 255 271 1 2
CASP9 RPTOR 0 0 282 283 1 2
CASP9 HSPB3 0 0 517 525 1 1
CASP9 NES 0 0 234 234 1 2
CASP9 HSP90B1 0 0 392 413 1 1
CASP9 NGB 0 0 282 282 1 1
CASP9 ENSG00000173366 0 0 187 211 1 1
CASP9 CYP19A1 0 0 233 232 1 2
CASP9 DIDO1 0 0 416 416 1 1
CASP9 SI 0 0 147 200 1 1
CASP9 CDH17 0 0 218 225 1 1
CASP9 HNRNPA1 0 0 181 181 1 1
CASP9 GZMA 0 0 166 165 1 1
CASP9 PNMA3 0 0 160 159 1 1
CASP9 ACTR3 117 0 0 209 1 1
CASP9 BCL2L11 0 0 758 823 1 2
CASP9 APIP 0 600 442 767 1 1
CASP9 SKA3 0 0 0 207 1 1
CASP9 TYK2 0 0 129 188 1 1
CASP9 DAPK1 0 0 270 270 1 2
CASP9 PLCG1 0 0 218 231 1 1
CASP9 JUN 270 0 682 782 1 2
CASP9 ITPR3 0 0 297 297 1 1
CASP9 CCNA2 0 0 602 602 1 1
CASP9 TK1 0 0 73 170 1 1
CASP9 NOS1 0 0 271 271 1 1
CASP9 CASP1 0 0 681 306 1 2
CASP9 AKT1S1 0 0 278 278 1 1
CASP9 PLAT 0 0 120 155 1 1
CASP9 SNCA 0 0 324 323 1 2
CASP9 ENSG00000233917 0 0 0 155 1 1
CASP9 CD27 0 0 181 181 1 1
CASP9 BAG5 0 0 142 227 1 1
CASP9 CHEK1 0 0 501 505 1 2
CASP9 DNTT 0 0 704 718 1 1
CASP9 CDC20 0 0 180 209 1 1
CASP9 MAP2K3 0 0 323 330 1 1
CASP9 PIK3CG 0 0 306 330 1 1
CASP9 JAK3 0 0 124 183 1 1
CASP9 BOK 0 0 391 531 1 1
CASP9 HIC1 0 0 53 171 1 1
CASP9 COL18A1 0 0 180 179 1 1
CASP9 HSPA1A 0 0 322 456 1 1
CASP9 CERS5 0 0 166 165 1 1
CASP9 SRF 213 0 113 272 1 1
CASP9 AIF1 0 0 248 260 1 2
CASP9 TNFSF10 0 0 653 653 1 2
CASP9 CAV1 0 0 276 276 1 2
CASP9 ERBB4 0 0 181 197 1 1
CASP9 FUNDC1 0 0 126 183 1 2
CASP9 BIK 0 0 505 505 1 2
CASP9 CALR 0 0 317 351 1 1
CASP9 GAP43 0 0 163 163 1 1
CASP9 CD8A 0 0 420 420 1 1
CASP9 IRS2 0 0 152 151 1 1
CASP9 HAVCR2 0 0 144 167 1 1
CASP9 EIF2AK2 0 0 124 258 1 2
CASP9 IGFBP3 0 0 259 258 1 2
CASP9 MFN1 0 0 366 395 1 2
CASP9 TMEM106A 0 0 46 198 1 1
CASP9 MMP2 0 0 519 519 1 2
CASP9 TFAM 0 0 293 293 1 2
CASP9 RIPK2 0 0 357 394 1 2
CASP9 CRK 0 0 153 247 1 1
CASP9 TNFRSF8 0 0 208 208 1 1
CASP9 ACAP1 0 0 0 163 1 1
CASP9 LAMP2 0 0 278 278 1 2
CASP9 CAPN2 213 0 309 466 1 2
CASP9 JAG1 0 0 148 162 1 1
CASP9 VCP 113 0 134 304 1 2
CASP9 LCK 0 0 218 235 1 1
CASP9 MSLN 0 0 255 266 1 1
CASP9 FYN 0 0 214 232 1 1
CASP9 ZBTB38 0 0 324 334 1 1
CASP9 HIP1 270 0 45 284 1 1
CASP9 GRB2 0 0 284 288 1 1
CASP9 GTF2F1 0 0 0 161 1 1
CASP9 SHH 0 0 255 255 1 2
CASP9 ERN2 0 0 134 172 1 1
CASP9 PRDX1 0 0 161 386 1 1
CASP9 EIF3M 0 0 508 550 1 1
CASP9 CDC25C 0 0 595 620 1 2
CASP9 SOD1 0 0 402 455 1 2
CASP9 LTA 0 0 182 410 1 1
CASP9 ARNT 270 0 208 397 1 2
CASP9 DNAJC3 0 0 162 161 1 1
CASP9 IL36RN 0 0 0 153 1 1
CASP9 BMI1 0 0 251 250 1 1
CASP9 CCR5 0 0 150 181 1 1
CASP9 MLKL 0 0 460 472 1 2
CASP9 BCL10 213 0 364 478 1 1
CASP9 SMDT1 0 0 150 203 1 1
CASP9 PTPRC 0 0 261 261 1 1
CASP9 BCL2L12 0 0 217 217 1 1
CASP9 ESR2 0 0 341 368 1 1
CASP9 SOX9 0 0 156 155 1 1
CASP9 ASAP3 0 0 0 163 1 1
CASP9 SIRT7 0 0 210 210 1 2
CASP9 CD24 0 0 176 175 1 2
CASP9 ZEB1 0 0 264 264 1 2
CASP9 CTAG1B 0 0 155 154 1 1
CASP9 CCNB2 0 0 170 207 1 1
CASP9 ADORA2A 0 0 144 157 1 1
CASP9 ICAM1 0 0 369 383 1 2
CASP9 GABARAPL1 0 0 264 284 1 2
CASP9 TUBA1B 0 0 0 153 1 1
CASP9 SPP1 0 0 218 218 1 2
CASP9 CDKN1A 0 0 607 618 1 2
CASP9 NKRF 0 0 175 187 1 1
CASP9 BCLAF1 0 0 112 150 1 1
CASP9 HNRNPH1 270 0 67 289 1 1
CASP9 BID 0 0 630 658 1 2
CASP9 HSPA8 0 0 354 462 1 2
CASP9 GSR 0 0 439 439 1 1
CASP9 EPCAM 0 0 193 193 1 2
CASP9 GSN 0 0 687 687 1 1
CASP9 EIF4G1 0 900 180 915 1 2
CASP9 AR 0 0 358 378 1 2
CASP9 RHOA 0 0 325 337 1 2
CASP9 PARP1 0 800 651 949 1 2
CASP9 TOMM40 0 0 150 169 1 1
CASP9 AURKA 0 0 236 243 1 2
CASP9 LRRC59 0 0 0 167 1 1
CASP9 KLRK1 0 0 167 167 1 1
CASP9 TNNI3 0 0 202 203 1 1
CASP9 IMMP2L 0 0 292 292 1 1
CASP9 BAX 270 0 739 834 1 2
CASP9 EXOSC3 0 0 0 189 1 1
CASP9 TIMP1 0 0 362 363 1 1
CASP9 IL36A 0 0 0 153 1 1
CASP9 CXCL12 0 0 244 243 1 2
CASP9 GMEB1 270 0 0 313 1 1
CASP9 SELP 0 0 143 166 1 1
CASP9 INS 0 0 509 528 1 2
CASP9 ATG13 0 0 260 288 1 2
CASP9 TMOD3 0 0 0 159 1 1
CASP9 ACTB 0 0 804 863 1 2
CASP9 AK2 0 0 416 416 1 1
CASP9 FOXG1 0 0 60 230 1 1
CASP9 EMR2 0 0 0 183 1 1
CASP9 HIST2H2AA 0 0 158 157 1 1
CASP9 SELL 0 0 154 153 1 1
CASP9 ATP6V1G2 0 0 108 169 1 1
CASP9 SLA2 0 0 308 307 1 1
CASP9 FGF1 0 0 167 167 1 1
CASP9 CD40 0 0 287 292 1 2
CASP9 DNMT1 0 0 323 330 1 2
CASP9 GLP1R 0 0 167 178 1 1
CASP9 STUB1 0 0 203 203 1 2
CASP9 B2M 0 0 194 195 1 1
CASP9 MMP9 0 0 601 619 1 2
CASP9 KEAP1 0 0 395 396 1 2
CASP9 MAPK3 213 900 650 970 1 2
CASP9 PROM1 0 0 329 339 1 2
CASP9 SIRT3 0 0 323 323 1 2
CASP9 ANGPT1 0 0 155 154 1 1
CASP9 THY1 0 0 181 181 1 1
CASP9 CRYZ 0 0 202 208 1 1
CASP9 GLI3 0 0 150 163 1 1
CASP9 HIST1H4J 0 0 216 216 1 1
CASP9 ANXA4 0 0 99 575 1 1
CASP9 SQSTM1 270 0 459 607 1 2
CASP9 BNIP3 0 0 501 558 1 2
CASP9 SPAG9 0 0 140 159 1 1
CASP9 IL3 0 0 268 268 1 1
CASP9 PDIA2 0 0 0 185 1 1
CASP9 HSP90AA1 0 0 557 572 1 2
CASP9 HDAC4 0 0 248 248 1 2
CASP9 HIST2H2AA3 0 0 158 157 1 1
CASP9 IL21 0 0 0 193 1 1
CASP9 HPGDS 0 0 393 392 1 1
CASP9 FBXW7 0 0 164 163 1 2
CASP9 SOX2 0 0 294 294 1 2
CASP9 HTRA2 0 0 667 678 1 1
CASP9 CEBPA 0 0 181 193 1 1
CASP9 PSEN1 0 0 253 269 1 2
CASP9 TP73 0 0 212 334 1 2
CASP9 ABCA4 0 0 51 158 1 1
CASP9 CRP 0 0 231 248 1 2
CASP9 COX4I1 0 0 653 689 1 1
CASP9 UGCG 0 0 162 161 1 1
CASP9 PTCH2 0 0 66 164 1 1
CASP9 HMMR 0 0 94 158 1 1
CASP9 TOMM20 0 0 374 388 1 2
CASP9 RAC2 0 0 157 203 1 1
CASP9 A26B3 0 0 0 155 1 1
CASP9 NWD1 0 0 113 207 1 1
CASP9 EIF2S1 0 0 518 521 1 2
CASP9 RASSF1 0 0 150 169 1 1
CASP9 MMP12 0 0 124 158 1 1
CASP9 ANPEP 0 0 151 150 1 1
CASP9 KDR 0 0 380 380 1 2
CASP9 MITF 0 0 169 178 1 2
CASP9 JAK1 0 0 296 312 1 2
CASP9 RNF2 270 0 53 289 1 1
CASP9 HIST1H4D 0 0 216 216 1 1
CASP9 HMOX1 0 0 561 561 1 2
CASP9 FOXP3 0 0 181 181 1 2
CASP9 IL32 0 0 174 173 1 1
CASP9 TCHP 0 0 517 517 1 1
CASP9 TBK1 0 0 143 198 1 2
CASP9 TUBB2A 0 0 75 190 1 1
CASP9 LIN28B 0 0 63 164 1 1
CASP9 GLRX 0 0 159 158 1 1
CASP9 RB1 270 0 325 497 1 2
CASP9 MMP10 0 0 67 170 1 1
CASP9 RIPK3 0 0 459 471 1 2
CASP9 GSTM4 0 0 0 215 1 1
CASP9 DHCR24 0 0 118 194 1 1
CASP9 USP7 0 0 143 158 1 1
CASP9 CDCA8 0 0 142 161 1 1
CASP9 PRKCD 0 0 459 470 1 2
CASP9 CDKN1B 0 0 467 487 1 2
CASP9 GLUL 0 0 146 238 1 1
CASP9 BNIP3L 0 0 279 409 1 2
CASP9 F2R 0 0 155 154 1 1
CASP9 STAT5B 0 0 310 309 1 1
CASP9 TSC2 0 0 390 393 1 2
CASP9 PPM1D 0 0 134 152 1 1
CASP9 VDAC1 0 0 520 520 1 2
CASP9 TGFB1 0 0 266 308 1 2
CASP9 GADD45G 0 0 167 167 1 1
CASP9 SRC 0 0 505 516 1 2
CASP9 PINX1 0 0 62 161 1 1
CASP9 ACTL6A 0 0 0 204 1 1
CASP9 CDC42 0 0 294 307 1 2
CASP9 TUBA1C 0 0 0 153 1 1
CASP9 USP8 0 0 306 319 1 1
CASP9 GPX6 0 0 57 313 1 1
CASP9 SLC34A1 0 0 357 357 1 1
CASP9 HSPA12A 0 0 57 182 1 1
CASP9 MB 0 0 150 281 1 2
CASP9 SHISA5 0 0 114 177 1 1
CASP9 MCU 0 0 172 171 1 2
CASP9 CD47 0 0 170 169 1 2
CASP9 TNFSF11 0 0 246 245 1 2
CASP9 ACTG2 0 0 0 175 1 1
CASP9 SPTAN1 0 0 342 366 1 1
CASP9 DHFRL1 0 0 0 153 1 1
CASP9 APOE 0 0 206 210 1 2
CASP9 PCSK9 0 0 286 301 1 1
CASP9 VDAC3 0 0 248 343 1 1
CASP9 SLC2A4 0 0 184 183 1 1
CASP9 EVA1A 0 0 57 161 1 2
CASP9 FBXW5 0 0 0 555 1 1
CASP9 IL36B 0 0 0 153 1 1
CASP9 FOXO3 0 0 556 580 1 2
CASP9 EIF2AK3 0 0 620 625 1 2
CASP9 HNF4A 0 0 244 243 1 1
CASP9 STAT6 0 0 138 198 1 1
CASP9 UBE2C 0 0 70 182 1 1
CASP9 TUBB8B 0 0 0 161 1 1
CASP9 TNFSF12 0 0 276 276 1 1
CASP9 TP53INP1 0 0 183 183 1 2
CASP9 BNIP1 0 0 164 163 1 2
CASP9 BIRC6 675 0 469 855 1 1
CASP9 TUBB8 0 0 0 161 1 1
CASP9 CDKN3 0 0 406 406 1 1
CASP9 TLR3 0 0 259 290 1 2
CASP9 CIB1 0 0 181 212 1 1
CASP9 SLC25A5 0 0 76 221 1 1
CASP9 LGALS3 0 0 202 216 1 2
CASP9 DNAJB1 0 0 261 261 1 2
CASP9 ATG3 0 0 376 417 1 2
CASP9 TXNDC9 0 0 193 243 1 1
CASP9 FLT1 0 0 263 263 1 1
CASP9 FOXO4 0 0 267 267 1 1
CASP9 CAAP1 0 0 155 175 1 1
CASP9 AXL 0 0 151 170 1 2
CASP9 HSP90AB1 0 0 74 360 1 2
CASP9 GAS2 0 0 73 175 1 1
CASP9 CYLD 0 0 248 306 1 1
CASP9 EIF4EBP1 0 0 459 459 1 2
CASP9 KRT18 0 0 285 284 1 1
CASP9 BIRC8 825 0 837 990 1 1
CASP9 CXCL10 0 0 213 213 1 2
CASP9 TYMS 0 0 262 262 1 1
CASP9 FGG 0 0 460 460 1 1
CASP9 ID2 0 0 134 157 1 1
CASP9 CCNG2 0 0 161 179 1 1
CASP9 GPT 0 0 450 450 1 1
CASP9 PDE5A 0 0 144 245 1 1
CASP9 PHGDH 0 0 156 155 1 1
CASP9 BCL6 0 0 142 215 1 1
CASP9 PINK1 0 0 339 344 1 2
CASP9 IL24 0 0 284 284 1 2
CASP9 GSK3A 0 0 139 229 1 1
CASP9 GJA1 0 0 242 241 1 1
CASP9 BIRC5 728 0 574 900 1 2
CASP9 SIRT4 0 0 218 218 1 1
CASP9 CD34 0 0 375 375 1 2
CASP9 PRDX3 0 0 181 266 1 1
CASP9 NGF 0 0 414 431 1 2
CASP9 ACTL10 0 0 0 155 1 1
CASP9 ENSG00000274276 0 0 167 190 1 1
CASP9 HMGA2 0 0 176 175 1 1
CASP9 TUBAL3 0 0 0 151 1 1
CASP9 ERBB2 0 0 519 536 1 2
CASP9 IRF3 0 0 287 286 1 2
CASP9 RHD 0 0 163 163 1 1
CASP9 BBC3 0 0 560 560 1 2
CASP9 DENR 0 0 193 193 1 1
CASP9 TH 0 0 264 264 1 2
CASP9 NR1I2 0 0 134 151 1 1
CASP9 CARD6 0 0 162 161 1 1
CASP9 TNFSF8 0 0 116 154 1 1
CASP9 MGAM 0 0 150 203 1 1
CASP9 CCNE2 0 0 218 302 1 1
CASP9 MAP3K1 0 0 215 215 1 1
CASP9 PYCARD 0 0 389 467 1 2
CASP9 AIFM1 0 0 294 673 1 1
CASP9 TLR9 0 0 202 226 1 2
CASP9 TUBA3C 0 0 0 161 1 1
CASP9 CARD8 270 800 514 922 1 1
CASP9 FAS 0 0 683 721 1 2
CASP9 CD4 0 0 427 431 1 2
CASP9 HSPH1 0 0 82 199 1 1
CASP9 CA9 0 0 218 218 1 1
CASP9 MBTPS1 0 0 113 174 1 1
CASP9 ATF4 0 0 404 422 1 2
CASP9 VCAM1 0 0 270 284 1 1
CASP9 AKT1 213 900 805 984 1 2
CASP9 TGFB2 0 0 155 154 1 1
CASP9 CAPN1 0 0 427 444 1 2
CASP9 HIST1H4C 0 0 216 216 1 1
CASP9 PPARG 0 0 421 432 1 2
CASP9 CSF2 0 0 324 323 1 1
CASP9 PARP4 0 800 74 821 1 1
CASP9 ACTL8 0 0 0 155 1 1
CASP9 MKI67 0 0 97 412 1 2
CASP9 E2F4 0 0 181 188 1 1
CASP9 KCNJ6 0 0 394 394 1 1
CASP9 NOX4 0 0 310 309 1 2
CASP9 DROSHA 0 0 170 266 1 1
CASP9 XIAP 981 900 989 999 1 2
CASP9 VMP1 0 0 103 196 1 2
CASP9 PPP2R4 0 0 488 488 1 1
CASP9 PARL 0 0 153 159 1 1
CASP9 RUNX2 0 0 233 232 1 2
CASP9 PSMD5 0 0 153 152 1 1
CASP9 FGFR1 0 0 175 175 1 1
CASP9 CD247 0 0 325 331 1 1
CASP9 NTRK2 0 0 218 235 1 1
CASP9 ATF6 0 0 562 604 1 2
CASP9 NLRC4 0 0 360 377 1 2
CASP9 IKBKB 0 0 414 463 1 2
CASP9 GSTM1 0 0 142 204 1 1
CASP9 TPT1 0 0 185 185 1 1
CASP9 KLF4 0 0 180 192 1 2
CASP9 DUOX1 0 0 232 231 1 1
CASP9 PANX1 0 0 150 166 1 1
CASP9 IL7 0 0 240 239 1 1
CASP9 ITK 0 0 55 237 1 1
CASP9 NT5E 0 0 113 174 1 1
CASP9 CD44 0 0 391 390 1 2
CASP9 MMP25 0 0 0 199 1 1
CASP9 BDNF 0 0 394 418 1 2
CASP9 TRAP1 0 0 113 163 1 2
CASP9 HDC 0 0 75 157 1 1
CASP9 VDR 0 0 167 183 1 2
CASP9 PIK3R2 0 0 203 329 1 1
CASP9 CASP2 209 0 803 417 1 1
CASP9 MMP3 0 0 274 350 1 1
CASP9 DCK 0 0 150 179 1 1
CASP9 TNF 0 0 684 721 1 2
CASP9 NBR1 0 0 125 162 1 2
CASP9 RHAG 0 0 261 261 1 1
CASP9 YBX1 0 0 123 218 1 1
CASP9 TUBB4B 0 0 0 161 1 1
CASP9 PTMA 0 0 572 572 1 1
CASP9 XDH 0 0 54 156 1 1
CASP9 C22orf29 0 0 730 730 1 1
CASP9 HSPA2 0 0 90 327 1 1
CASP9 CBSL 0 0 167 190 1 1
CASP9 RBFOX3 0 0 301 332 1 1
CASP9 SMPD2 0 0 243 242 1 1
CASP9 PPP1R15A 0 0 345 349 1 2
CASP9 POTEB2 0 0 0 155 1 1
CASP9 USP14 0 0 187 187 1 2
CASP9 EEF2 0 0 171 172 1 2
CASP9 MMP7 0 0 250 326 1 1
CASP9 FIS1 0 0 390 403 1 2
CASP9 BAG4 0 0 115 204 1 1
CASP9 NAIP 297 0 590 751 1 1
CASP9 VCL 0 0 260 265 1 1
CASP9 PEBP1 0 0 160 161 1 1
CASP9 PRDX4 0 0 95 277 1 1
CASP9 FGF2 0 0 393 392 1 2
CASP9 BCAP31 0 0 258 258 1 1
CASP9 RELB 0 0 269 269 1 2
CASP9 DRAM1 0 0 202 208 1 2
CASP9 BCL2A1 0 0 501 583 1 1
CASP9 MMP8 0 0 90 238 1 1
CASP9 SNCG 0 0 66 227 1 1
CASP9 FKBP1C 0 0 0 560 1 1
CASP9 TXNIP 0 0 234 234 1 2
CASP9 SRSF2 0 0 193 193 1 1
CASP9 BMF 0 0 518 525 1 1
CASP9 RPS6KA2 0 0 184 201 1 1
CASP9 VWF 0 0 181 195 1 1
CASP9 PRDX2 0 0 166 295 1 1
CASP9 IL5 0 0 157 156 1 1
CASP9 CD70 0 0 151 150 1 1
CASP9 TFRC 0 0 195 195 1 1
CASP9 IFNAR1 0 0 156 155 1 1
CASP9 HIST1H4H 0 0 216 216 1 1
CASP9 CCND2 0 0 294 304 1 1
CASP9 EDEM1 0 0 161 178 1 2
CASP9 GSTP1 0 0 255 254 1 1
CASP9 NFKB2 0 0 260 302 1 1
CASP9 ATG4B 0 0 140 181 1 2
CASP9 ATP12A 0 0 142 166 1 1
CASP9 TNFAIP3 0 0 170 182 1 2
CASP9 PTCH1 270 0 193 549 1 1
CASP9 POTEI 0 0 0 332 1 1
CASP9 GCG 0 0 166 165 1 1
CASP9 MAPK1 270 900 568 966 1 2
CASP9 IRF7 0 0 145 167 1 1
CASP9 IGF1 0 0 505 517 1 2
CASP9 PARP3 0 800 0 815 1 1
CASP9 DDX53 0 0 215 228 1 1
CASP9 MMP27 0 0 0 207 1 1
CASP9 UVRAG 0 0 204 204 1 2
CASP9 CCND3 0 0 362 386 1 1
CASP9 RNF41 0 0 398 399 1 1
CASP9 SOCS1 0 0 184 183 1 1
CASP9 BTK 0 0 180 198 1 1
CASP9 PKM 0 0 234 311 1 1
CASP9 GADD45A 0 0 416 428 1 1
CASP9 CNR1 0 0 181 193 1 1
CASP9 CDH5 0 0 146 178 1 1
CASP9 ATF3 0 0 282 282 1 2
CASP9 EPOR 0 0 134 165 1 1
CASP9 NTRK1 0 0 294 310 1 1
CASP9 HMGCR 0 0 217 217 1 1
CASP9 IFT43 0 0 504 504 1 1
CASP9 EFS 0 0 469 469 1 1
CASP9 HSPA9 0 0 184 268 1 1
CASP9 CBL 0 0 151 226 1 1
CASP9 SGK1 0 0 174 244 1 2
CASP9 IRS1 0 0 294 294 1 2
CASP9 ACTR10 0 0 0 155 1 1
CASP9 LOX 0 0 218 218 1 2
CASP9 RRAD 0 0 138 184 1 1
CASP9 TNFAIP8 0 0 147 534 1 1
CASP9 BAD 0 0 517 520 1 2
CASP9 RPS6KB1 0 0 558 568 1 2
CASP9 AGTR1 0 0 142 155 1 1
CASP9 REM1 0 0 0 321 1 1
CASP9 MUC1 0 0 206 206 1 1
CASP9 PGR 0 0 268 282 1 1
CASP9 HIST1H4B 0 0 216 216 1 1
CASP9 NLRP2 0 0 323 323 1 1
CASP9 CDK1 0 0 602 623 1 2
CASP9 EIF4E 0 900 294 926 1 2
CASP9 SERPINE1 0 0 187 187 1 1
CASP9 AHR 0 0 218 218 1 2
CASP9 PRKDC 0 0 262 274 1 2
CASP9 PPP2CA 0 0 474 474 1 1
CASP9 LEPREL2 0 0 293 293 1 1
CASP9 HIST2H2BE 0 0 170 169 1 1
CASP9 TNFRSF10D 0 0 422 492 1 1
CASP9 CCND1 0 0 704 755 1 2
CASP9 CD274 0 0 240 256 1 2
CASP9 RCC1 0 0 209 209 1 1
CASP9 ACTA2 0 0 45 230 1 1
CASP9 NOS3 0 0 459 459 1 2
CASP9 ANXA2 0 0 150 530 1 1
CASP9 ABCG2 0 0 370 375 1 1
CASP9 BLNK 0 0 45 295 1 1
CASP9 IRAK2 0 0 90 169 1 1
CASP9 NCF1 0 0 210 219 1 1
CASP9 CD19 0 0 391 390 1 1
CASP9 BCL2L2 0 0 654 713 1 1
CASP9 ATR 0 0 212 225 1 2
CASP9 DDIT4 0 0 206 206 1 2
CASP9 RHEB 0 0 181 196 1 2
CASP9 RNASEL 0 0 134 241 1 1
CASP9 HPRT1 117 0 181 245 1 1
CASP9 FEM1B 0 0 360 392 1 1
CASP9 BAK1 0 0 595 662 1 2
CASP9 ANXA7 0 0 93 573 1 1
CASP9 AVEN 0 900 498 947 1 1
CASP9 BCL2 0 0 457 581 1 2
CASP9 MAP2K2 213 0 119 302 1 1
CASP9 MYB 0 0 141 158 1 1
CASP9 MDK 0 0 63 221 1 1
CASP9 HIST2H4B 0 0 216 216 1 1
CASP9 CD38 0 0 181 181 1 2
CASP9 DFFA 0 0 624 629 1 1
CASP9 LIN28A 0 0 112 208 1 1
CASP9 TUBA1A 0 0 0 153 1 1
CASP9 CARD18 0 0 306 306 1 1
CASP9 CTLA4 0 0 363 363 1 2
CASP9 ATP2A2 0 0 141 214 1 1
CASP9 CD97 0 0 0 213 1 1
CASP9 WNT10B 0 0 90 170 1 1
CASP9 PECAM1 0 0 325 336 1 1
CASP9 CAT 0 0 652 665 1 2
CASP9 PTK2B 0 0 161 166 1 1
CASP9 HTRA4 270 0 0 290 1 1
CASP9 PDPK1 0 650 309 757 1 2
CASP9 DUSP6 0 0 96 235 1 1
CASP9 CYC1 0 0 243 244 1 1
CASP9 CAST 0 0 394 401 1 2
CASP9 NUBP2 0 0 180 179 1 1
CASP9 HRK 0 0 518 521 1 1
CASP9 CCNE1 0 0 293 459 1 1
CASP9 TXN 0 0 391 436 1 1
CASP9 CANX 0 0 324 338 1 2
CASP9 LCP1 0 0 0 174 1 1
CASP9 NT5C2 0 0 0 206 1 1
CASP9 ENSG00000264813 0 0 167 167 1 1
CASP9 HGF 0 0 281 281 1 2
CASP9 DNAJB7 0 0 322 321 1 1
CASP9 POU5F1 0 0 294 295 1 2
CASP9 MMP11 0 0 67 220 1 1
CASP9 NFATC1 0 0 150 170 1 2
CASP9 AASDHPPT 0 0 62 155 1 1
CASP9 E2F5 0 0 180 187 1 1
CASP9 NTRK3 0 0 134 187 1 1
CASP9 MYOD1 0 0 165 165 1 1
CASP9 GAPDHS 0 0 0 384 1 1
CASP9 WIPI1 0 0 73 169 1 2
CASP9 CASP5 0 0 519 264 1 1
CASP9 DNM1L 0 0 406 448 1 2
CASP9 PPFIBP2 0 0 160 179 1 1
CASP9 SLC9C2 0 0 0 152 1 1
CASP9 PTEN 0 0 602 630 1 2
CASP9 MBP 0 0 167 167 1 2
CASP9 TXN2 0 0 510 540 1 1
CASP9 MAPK7 0 0 245 257 1 1
CASP9 ACTR1A 0 0 0 155 1 1
CASP9 VEGFA 0 0 602 602 1 2
CASP9 SREBF1 0 0 203 223 1 1
CASP9 HIST1H4K 0 0 216 216 1 1
CASP9 BAG1 0 0 294 294 1 2
CASP9 TP53BP2 0 0 156 155 1 2
CASP9 MARK2 0 0 162 161 1 1
CASP9 NGFR 0 0 294 294 1 1
CASP9 E2F3 0 0 204 211 1 1
CASP9 MAPK10 0 0 261 277 1 2
CASP9 HIST1H4A 0 0 216 216 1 1
CASP9 LMNB2 0 0 282 309 1 1
CASP9 TIMP3 0 0 181 181 1 1
CASP9 ENSG00000258947 0 0 128 267 1 1
CASP9 MAPK14 0 0 391 557 1 2
CASP9 LRRFIP2 0 0 73 158 1 1
CASP9 CFL1 117 0 167 233 1 1
CASP9 TNFRSF9 0 0 373 373 1 1
CASP9 LEP 0 0 209 209 1 1
CASP9 SYK 0 0 199 298 1 2
CASP9 COMMD3-BMI1 0 0 243 242 1 1
CASP9 KIT 0 0 282 282 1 2
CASP9 NFKBIA 0 0 596 625 1 2
CASP9 ACTL7A 0 0 0 155 1 1
CASP9 CCNA1 0 0 208 208 1 1
CASP9 C12orf5 0 0 150 168 1 1
CASP9 WT1 0 0 193 205 1 1
CASP9 AMBRA1 0 0 174 175 1 2
CASP9 LDHA 0 0 210 224 1 2
CASP9 ASAP2 0 0 0 163 1 1
CASP9 CA4 0 0 150 183 1 1
CASP9 MDM4 0 0 247 263 1 1
CASP9 CCL3 0 0 170 169 1 1
CASP9 CTSG 0 0 160 159 1 1
CASP9 BPHL 0 0 125 163 1 1
CASP9 G6PD 0 0 180 179 1 1
CASP9 NTF4 0 0 167 167 1 1
CASP9 EZR 0 0 622 624 1 1
CASP9 ATM 0 0 517 538 1 2
CASP9 SHC1 0 0 261 274 1 1
CASP9 CTSD 0 0 381 391 1 2
CASP9 AXIN1 0 0 212 212 1 1
CASP9 TNFRSF10C 0 0 413 484 1 1
CASP9 IGF2 0 0 233 232 1 1
CASP9 CYGB 0 0 95 399 1 1
CASP9 DAPK2 0 0 196 196 1 2
CASP9 IRAK4 0 0 108 167 1 1
CASP9 COL1A1 0 0 138 183 1 2
CASP9 NPM1 0 0 181 181 1 1
CASP9 NAMPT 0 0 141 160 1 2
CASP9 FLT3 0 0 233 232 1 2
CASP9 SNAI1 0 0 391 403 1 1
CASP9 IL10 0 0 452 462 1 2
CASP9 CDK7 0 0 207 207 1 1
CASP9 UBE2S 0 0 137 151 1 1
CASP9 GFAP 0 0 282 297 1 2
CASP9 ACTG1 0 0 218 433 1 1
CASP9 SKAP2 0 0 0 208 1 1
CASP9 NR1H4 0 0 141 158 1 1
CASP9 DLG4 0 0 193 193 1 2
CASP9 GDF15 0 0 204 204 1 1
CASP9 CCAR1 0 0 252 252 1 1
CASP9 WNT10A 0 0 95 204 1 1
CASP9 ATG7 270 0 937 955 1 2
CASP9 TGFBR2 0 0 202 220 1 1
CASP9 DMD 0 0 96 199 1 2
CASP9 SELE 0 0 170 169 1 1
CASP9 TJP1 0 0 244 258 1 1
CASP9 ADAM17 0 0 189 189 1 1
CASP9 HMOX2 0 0 144 207 1 1
CASP9 SPHK1 0 0 220 220 1 2
CASP9 NFKBIB 0 0 166 287 1 1
CASP9 TIMP2 0 0 269 269 1 1
CASP9 DFFB 0 0 653 681 1 1
CASP9 NDUFB8 0 0 151 150 1 1
CASP9 MAP1LC3B 0 0 596 617 1 2
CASP9 SPHK2 0 0 211 211 1 1
CASP9 HSPB2 0 0 519 528 1 1
CASP9 TERT 0 0 323 323 1 2
CASP9 ANXA6 0 0 85 568 1 1
CASP9 DYRK1A 0 0 207 229 1 1
CASP9 TYRP1 0 0 171 171 1 1
CASP9 ENSG00000255819 0 0 167 167 1 1
CASP9 GLI1 0 0 241 252 1 2
CASP9 HSPB1 117 0 518 577 1 2
CASP9 MST1R 0 0 157 189 1 1
CASP9 TGFBR1 0 0 168 187 1 1
CASP9 S100A4 0 0 155 154 1 1
CASP9 AKT3 0 900 370 939 1 2
CASP9 SPRED2 0 0 57 200 1 2
CASP9 MMP13 0 0 240 239 1 2
CASP9 UNC5B 0 650 114 682 1 1
CASP9 RARA 0 0 115 163 1 2
CASP9 IKBKG 0 0 294 294 1 1
CASP9 GPX1 0 0 293 422 1 1
CASP9 MT-CYB 0 0 145 164 1 1
CASP9 FN1 0 0 421 422 1 2
CASP9 CASR 0 0 142 192 1 2
CASP9 VTN 0 0 182 181 1 1
CASP9 MT-CO1 0 0 240 239 1 1
CASP9 TBP 0 0 150 169 1 1
CASP9 TIAL1 0 0 44 192 1 1
CASP9 NCAM1 0 0 142 165 1 1
CASP9 EIF4G2 0 900 54 903 1 1
CASP9 CDC25B 0 0 204 260 1 1
CASP9 ULK1 0 0 286 306 1 2
CASP9 MAP3K12 0 0 210 264 1 1
CASP9 SOD3 0 0 118 174 1 1
CASP9 PRKCA 0 0 293 293 1 1
CASP9 STMN1 0 0 172 171 1 1
CASP9 RPS6KA1 0 0 358 358 1 1
CASP9 GPX3 0 0 81 326 1 1
CASP9 ZBTB4 0 0 308 318 1 1
CASP9 MRPL44 0 0 0 151 1 1
CASP9 ELANE 0 0 210 210 1 1
CASP9 ESR1 0 0 504 513 1 2
CASP9 RIF1 0 0 0 193 1 1
CASP9 NCL 0 0 181 181 1 2
CASP9 RAC1 0 0 134 183 1 2
CASP9 DUOX2 0 0 181 181 1 1
CASP9 HMGB1 117 0 335 387 1 2
CASP9 IFNB1 0 0 420 420 1 1
CASP9 PPP1CA 0 0 466 466 1 1
CASP9 CTSK 0 0 137 211 1 2
CASP9 LYN 213 0 231 383 1 1
CASP9 JTB 0 0 96 164 1 1
CASP9 DFNA5 0 0 276 276 1 1
CASP9 ACTL6B 0 0 0 174 1 1
CASP9 TUBB 0 0 120 256 1 1
CASP9 ACTBL2 0 0 0 155 1 1
CASP9 SMAD7 0 0 202 202 1 1
CASP9 BACE1 0 0 241 255 1 2
CASP9 PDCD1 0 0 155 154 1 2
CASP9 ITGAM 0 0 260 260 1 1
CASP9 MAP3K5 0 0 600 615 1 1
CASP9 MCL1 0 0 769 864 1 2
CASP9 SIRT1 0 0 467 486 1 2
CASP9 HECTD3 270 0 0 282 1 1
CASP9 POTEB3 0 0 0 155 1 1
CASP9 NOX1 0 0 244 243 1 1
CASP9 LMNB1 0 0 390 413 1 1
CASP9 TP53BP1 0 0 181 219 1 1
CASP9 CTSB 0 0 459 468 1 2
CASP9 MAPK8IP3 0 0 108 163 1 1
CASP9 ACTRT2 0 0 0 155 1 1
CASP9 IRF1 0 0 208 208 1 2
CASP9 ATP4A 0 0 141 165 1 1
CASP9 ELN 0 0 160 159 1 1
CASP9 PTPN1 0 0 325 325 1 1
CASP9 SLC6A3 0 0 145 157 1 1
CASP9 XBP1 0 0 501 516 1 2
CASP9 STAT2 0 0 123 186 1 1
CASP9 YAP1 0 0 151 166 1 2
CASP9 HIPK2 0 0 136 160 1 2
CASP9 TP63 0 0 81 205 1 2
CASP9 PRKD1 0 0 137 155 1 1
CASP9 ITGB3 0 0 416 416 1 1
CASP9 LGR5 0 0 150 175 1 1
CASP9 BCL2L14 0 0 232 359 1 1
CASP9 TIA1 0 0 55 153 1 1
CASP9 SYP 0 0 194 200 1 1
CASP9 WNT3A 0 0 162 217 1 2
CASP9 MT-ND1 0 0 95 234 1 1
CASP9 ATG5 0 0 566 663 1 2
CASP9 MAP2K6 0 0 184 193 1 1
CASP9 POTEH 0 0 0 155 1 1
CASP9 SYCP2 0 0 107 159 1 1
CASP9 POTEC 0 0 0 155 1 1
CASP9 CDC25A 0 0 374 406 1 1
CASP9 PARP2 0 800 93 836 1 1
CASP9 CD86 0 0 193 193 1 1
CASP9 NOD1 270 600 306 783 1 2
CASP9 CARD11 0 0 143 234 1 1
CASP9 PDIA3 0 0 155 258 1 1
CASP9 PGF 0 0 123 225 1 1
CASP9 IL2 0 0 413 412 1 1
CASP9 WEE1 0 0 293 308 1 1
CASP9 TLR6 0 0 87 175 1 1
CASP9 OLR1 0 0 159 158 1 2
CASP9 ANXA1 0 0 148 314 1 1
CASP9 ALDH1A1 0 0 161 162 1 1
CASP9 COX4I2 0 0 381 404 1 1
CASP9 ABCC1 0 0 259 258 1 1
CASP9 MAPT 0 0 227 226 1 2
CASP9 BECN1 0 0 683 763 1 2
CASP9 MAOB 0 0 163 163 1 1
CASP9 ABCB1 0 0 404 414 1 2
CASP9 SDC1 0 0 294 294 1 1
CASP9 LRRK2 0 0 152 217 1 2
CASP9 TMEM40 0 0 91 158 1 1
CASP9 CDKN2C 0 0 143 205 1 1
CASP9 HSH2D 0 0 261 261 1 1
CASP9 MET 0 0 321 336 1 2
CASP9 TRAF3 0 0 234 235 1 2
CASP9 PHB 0 0 242 241 1 1
CASP9 DUSP1 0 0 218 218 1 1
CASP9 FGF23 0 0 304 304 1 1
CASP9 MAPK11 0 0 193 293 1 1
CASP9 ANKRD45 0 0 0 152 1 1
CASP9 PMAIP1 0 0 710 713 1 2
CASP9 CDKN2B 0 0 172 214 1 1
CASP9 PIK3CB 0 0 231 258 1 1
CASP9 TLR2 0 0 282 305 1 2
CASP9 CERS6 0 0 211 211 1 1
CASP9 DCC 675 800 134 938 1 1
CASP9 BTRC 0 0 143 161 1 1
CASP9 HAX1 0 0 864 864 1 1
CASP9 NRAS 0 0 210 240 1 1
CASP9 DNM1 0 0 74 232 1 1
CASP9 HSPA5 0 0 654 708 1 2
CASP9 E2F1 0 0 251 258 1 2
CASP9 SOD2 0 0 458 467 1 2
CASP9 SMS 0 0 330 330 1 1
CASP9 GPX2 0 0 91 401 1 1
CASP9 CDK9 0 0 190 190 1 1
CASP9 EPAS1 0 0 74 235 1 2
CASP9 KRAS 0 0 392 468 1 2
CASP9 FOXO1 0 0 465 465 1 2
CASP9 SOCS3 0 0 213 213 1 1
CASP9 FOS 0 0 415 414 1 2
CASP9 FASLG 0 0 739 739 1 1
CASP9 YWHAZ 0 0 140 157 1 1
CASP9 TWIST1 0 0 171 171 1 1
CASP9 XAF1 0 0 284 289 1 1
CASP9 CRKL 0 0 150 386 1 1
CASP9 PTPN11 0 0 208 208 1 1
CASP9 MLEC 0 0 0 161 1 1
CASP9 FAF1 0 0 260 260 1 1
CASP9 STAT5A 0 0 321 321 1 1
CASP9 RNF34 270 0 0 270 1 1
CASP9 MMP24 0 0 0 188 1 1
CASP9 BIRC7 755 800 572 982 1 1
CASP9 CNKSR2 0 0 0 155 1 1
CASP9 PIK3CD 0 0 306 330 1 1
CASP9 MT-CO2 0 0 170 175 1 1
CASP9 CEBPB 0 0 165 189 1 2
CASP9 SMPD1 0 0 253 269 1 1
CASP9 ATG16L1 0 0 237 237 1 2
CASP9 TXNRD1 0 0 304 304 1 1
CASP9 DHFR 0 0 182 278 1 1
CASP9 CIITA 0 0 74 166 1 1
CASP9 PDIA4 0 0 112 248 1 1
CASP9 NOD2 0 0 244 255 1 2
CASP9 HCK 0 0 143 162 1 1
CASP9 RIPK1 0 0 556 566 1 2
CASP9 TUBA8 0 0 43 153 1 1
CASP9 CSF1 0 0 184 183 1 1
CASP9 RRM2 0 0 134 155 1 1
CASP9 HDAC1 0 0 334 343 1 2
CASP9 CRYAB 270 0 73 319 1 2
CASP9 PHB2 0 0 174 173 1 1
CASP9 PHC3 0 0 155 154 1 1
CASP9 WNT3 0 0 108 167 1 1
CASP9 GSK3B 0 0 451 563 1 2
CASP9 XRCC5 0 0 240 245 1 1
CASP9 EIF3A 0 900 96 905 1 1
CASP9 S100B 0 0 161 161 1 1
CASP9 GPX8 0 0 0 461 1 1
CASP9 FOLH1 0 0 181 181 1 1
CASP9 CCNG1 0 0 141 660 1 1
CASP9 SFN 0 0 225 240 1 2
CASP9 ACTL9 0 0 0 155 1 1
CASP9 ERCC1 0 0 211 211 1 1
CASP9 CDKN2A 0 0 426 455 1 2
CASP9 CASP4 0 0 652 304 1 2
CASP9 CHUK 0 0 459 493 1 1
CASP9 CUL3 0 0 166 165 1 2
CASP9 HIST2H4A 0 0 216 216 1 1
CASP9 WNT2 0 0 85 323 1 1
CASP9 NTF3 0 0 181 181 1 1
CASP9 RBL2 0 0 217 234 1 1
CASP9 TNFRSF10B 0 0 731 763 1 2
CASP9 TMOD1 0 0 0 199 1 1
CASP9 IL13 0 0 181 181 1 2
CASP9 REN 0 0 154 172 1 1
CASP9 GPER1 0 0 155 154 1 2
CASP9 ATG12 0 0 427 461 1 2
CASP9 ALOX5 0 0 243 242 1 1
CASP9 TNFSF13B 0 0 146 154 1 1
CASP9 ACE 0 0 181 181 1 1
CASP9 NOTCH2 0 0 232 244 1 1
CASP9 TMEM59L 0 0 95 234 1 1
CASP9 PPIA 0 0 166 190 1 1
CASP9 PTS 0 0 143 169 1 1
CASP9 CXCL5 0 0 95 183 1 1
CASP9 CYBB 0 0 284 284 1 2
CASP9 CD28 0 0 325 325 1 1
CASP9 MZB1 213 0 499 588 1 1
CASP9 VEGFC 0 0 194 194 1 1
CASP9 PLA2G6 0 0 150 159 1 1
CASP9 CARD16 0 0 308 414 1 1
CASP9 MMP14 0 0 161 183 1 1
CASP9 HSPA1B 0 0 113 288 1 1
CASP9 BRCA2 0 0 184 184 1 1
CASP9 PARG 0 0 123 215 1 1
CASP9 REL 0 0 316 318 1 2
CASP9 NLRP3 0 0 391 395 1 2
CASP9 KIAA1524 0 0 161 161 1 1
CASP9 PLD2 0 0 63 206 1 1
CASP9 HYPK 0 0 0 161 1 1
CASP9 CXCL1 0 0 211 255 1 2
CASP9 ATG4D 0 0 141 212 1 2
CASP9 HNRNPL 0 0 235 235 1 1
CASP9 RPSA 0 0 143 170 1 1
CASP9 ERBB3 0 0 250 264 1 1
CASP9 CASP3 870 900 915 988 1 2
CASP9 TUBE1 0 0 0 161 1 1
CASP9 NQO1 0 0 391 390 1 2
CASP9 F3 0 0 134 153 1 1
CASP9 PSMB9 0 0 137 150 1 1
CASP9 EEF1A1 0 900 155 913 1 1
CASP9 PTGS2 0 0 556 568 1 2
CASP9 TUBB2B 0 0 0 161 1 1
CASP9 TNFRSF21 0 0 538 538 1 1
CASP9 LIMK1 0 0 90 150 1 1
CASP9 TUBB6 0 0 0 161 1 1
CASP9 DAXX 0 0 277 292 1 1
CASP9 AFP 0 0 234 286 1 2
Ontologies
ID Category Term Effect Evidence PubMed
GO:0017124 Molecular Function SH3 domain binding enables IDA
GO:0004197 Molecular Function cysteine-type endopeptidase activity enables IDA
GO:0004197 Molecular Function cysteine-type endopeptidase activity enables TAS
GO:0097153 Molecular Function cysteine-type endopeptidase activity involved in apoptotic process enables IDA
GO:0097199 Molecular Function cysteine-type endopeptidase activity involved in apoptotic signaling pathway enables IBA
GO:0097199 Molecular Function cysteine-type endopeptidase activity involved in apoptotic signaling pathway enables IDA
GO:0097199 Molecular Function cysteine-type endopeptidase activity involved in apoptotic signaling pathway enables IMP
GO:0008047 Molecular Function enzyme activator activity enables TAS
GO:0008233 Molecular Function peptidase activity enables IDA
GO:0005515 Molecular Function protein binding enables IPI
GO:0019901 Molecular Function protein kinase binding enables IDA
GO:0006974 Biological Process DNA damage response involved_in IDA
GO:0006974 Biological Process DNA damage response involved_in IMP
GO:0006919 Biological Process activation of cysteine-type endopeptidase activity involved in apoptotic process involved_in IBA
GO:0008635 Biological Process activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c involved_in TAS
GO:0006915 Biological Process apoptotic process involved_in IBA
GO:0006915 Biological Process apoptotic process involved_in IMP
GO:0006915 Biological Process apoptotic process involved_in TAS
GO:0034644 Biological Process cellular response to UV involved_in IDA
GO:0071549 Biological Process cellular response to dexamethasone stimulus involved_in IEA
GO:1904019 Biological Process epithelial cell apoptotic process involved_in IEA
GO:0044346 Biological Process fibroblast apoptotic process involved_in IEA
GO:0034349 Biological Process glial cell apoptotic process involved_in IEA
GO:0097193 Biological Process intrinsic apoptotic signaling pathway involved_in IC
GO:0097193 Biological Process intrinsic apoptotic signaling pathway involved_in IDA
GO:0097193 Biological Process intrinsic apoptotic signaling pathway involved_in NAS
GO:0008630 Biological Process intrinsic apoptotic signaling pathway in response to DNA damage involved_in IBA
GO:0008630 Biological Process intrinsic apoptotic signaling pathway in response to DNA damage involved_in IMP
GO:0001822 Biological Process kidney development involved_in IEA
GO:0071887 Biological Process leukocyte apoptotic process involved_in IEA
GO:0051402 Biological Process neuron apoptotic process involved_in IEA
GO:0030220 Biological Process platelet formation involved_in TAS
GO:0043065 Biological Process positive regulation of apoptotic process involved_in IMP
GO:0043525 Biological Process positive regulation of neuron apoptotic process involved_in IEA
GO:0051604 Biological Process protein maturation involved_in IDA
GO:0016485 Biological Process protein processing involved_in IEA
GO:0032025 Biological Process response to cobalt ion involved_in IEA
GO:0032355 Biological Process response to estradiol involved_in IEA
GO:0001666 Biological Process response to hypoxia involved_in IEA
GO:0002931 Biological Process response to ischemia involved_in IEA
GO:0032496 Biological Process response to lipopolysaccharide involved_in IEA
GO:0042770 Biological Process signal transduction in response to DNA damage involved_in IDA
GO:0043293 Cellular Component apoptosome part_of IDA
GO:0043293 Cellular Component apoptosome part_of IPI
GO:0008303 Cellular Component caspase complex part_of IPI
GO:0005737 Cellular Component cytoplasm is_active_in IBA
GO:0005829 Cellular Component cytosol located_in IDA
GO:0005829 Cellular Component cytosol located_in TAS
GO:0005739 Cellular Component mitochondrion is_active_in IDA
GO:0005634 Cellular Component nucleus located_in IEA
GO:0032991 Cellular Component protein-containing complex part_of IDA
Pathways
Name DB ID
Apoptosis Reactome R-HSA-109581
Intrinsic Pathway for Apoptosis Reactome R-HSA-109606
Formation of apoptosome Reactome R-HSA-111458
Activation of caspases through apoptosome-mediated cleavage Reactome R-HSA-111459
Cytochrome c-mediated apoptotic response Reactome R-HSA-111461
SMAC (DIABLO) binds to IAPs Reactome R-HSA-111463
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes Reactome R-HSA-111464
SMAC, XIAP-regulated apoptotic response Reactome R-HSA-111469
Apoptotic factor-mediated response Reactome R-HSA-111471
PIP3 activates AKT signaling Reactome R-HSA-1257604
Signal Transduction Reactome R-HSA-162582
Disease Reactome R-HSA-1643685
Innate Immune System Reactome R-HSA-168249
Immune System Reactome R-HSA-168256
NOD1/2 Signaling Pathway Reactome R-HSA-168638
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways Reactome R-HSA-168643
AKT phosphorylates targets in the cytosol Reactome R-HSA-198323
PI3K/AKT Signaling in Cancer Reactome R-HSA-2219528
Caspase activation via Dependence Receptors in the absence of ligand Reactome R-HSA-418889
Caspase activation via extrinsic apoptotic signalling pathway Reactome R-HSA-5357769
Programmed Cell Death Reactome R-HSA-5357801
Diseases of signal transduction by growth factor receptors and second messengers Reactome R-HSA-5663202
Constitutive Signaling by AKT1 E17K in Cancer Reactome R-HSA-5674400
Intracellular signaling by second messengers Reactome R-HSA-9006925
Regulation of the apoptosome activity Reactome R-HSA-9627069
Nucleotide-binding oligomerization domain (NOD) pathway (WP1433) WikiPathways WP1433_r122867
Network map of SARS-CoV-2 signaling pathway (WP5115) WikiPathways WP5115_r124648
DNA IR-double strand breaks and cellular response via ATM (WP3959) WikiPathways WP3959_r118468
Integrated cancer pathway (WP1971) WikiPathways WP1971_r117762
Chromosomal and microsatellite instability in colorectal cancer (WP4216) WikiPathways WP4216_r123363
Alzheimer's disease (WP5124) WikiPathways WP5124_r123917
Measles virus infection (WP4630) WikiPathways WP4630_r123414
Hepatitis B infection (WP4666) WikiPathways WP4666_r123495
Nanomaterial induced apoptosis (WP2507) WikiPathways WP2507_r123897
Complement system in neuronal development and plasticity (WP5090) WikiPathways WP5090_r118898
Apoptosis modulation by HSP70 (WP384) WikiPathways WP384_r121706
Thyroid hormones production and peripheral downstream signaling effects (WP4746) WikiPathways WP4746_r123317
Amyotrophic lateral sclerosis (ALS) (WP2447) WikiPathways WP2447_r113794
miRNA regulation of prostate cancer signaling pathways (WP3981) WikiPathways WP3981_r108114
Alzheimer's disease and miRNA effects (WP2059) WikiPathways WP2059_r119468
miRNA regulation of p53 pathway in prostate cancer (WP3982) WikiPathways WP3982_r108115
Corticotropin-releasing hormone signaling pathway (WP2355) WikiPathways WP2355_r120664
NO/cGMP/PKG mediated neuroprotection (WP4008) WikiPathways WP4008_r123318
Parkinson's disease pathway (WP2371) WikiPathways WP2371_r119919
Acute viral myocarditis (WP4298) WikiPathways WP4298_r123508
DYRK1A (WP5180) WikiPathways WP5180_r122423
Focal adhesion: PI3K-Akt-mTOR-signaling pathway (WP3932) WikiPathways WP3932_r124527
Oxidative damage response (WP3941) WikiPathways WP3941_r123242
Fas ligand pathway and stress induction of heat shock proteins (WP314) WikiPathways WP314_r121827
Allograft rejection (WP2328) WikiPathways WP2328_r120805
MTHFR deficiency (WP4288) WikiPathways WP4288_r124269
Small cell lung cancer (WP4658) WikiPathways WP4658_r124606
RAC1/PAK1/p38/MMP2 pathway (WP3303) WikiPathways WP3303_r123243
Host-pathogen interaction of human coronaviruses - apoptosis (WP4864) WikiPathways WP4864_r124634
DNA damage response (WP707) WikiPathways WP707_r124174
Hepatitis C and hepatocellular carcinoma (WP3646) WikiPathways WP3646_r116732
Apoptosis (WP254) WikiPathways WP254_r118382
Pro-survival signaling of neuroprotectin D1 (WP5182) WikiPathways WP5182_r122168
Pancreatic adenocarcinoma pathway (WP4263) WikiPathways WP4263_r123405
TNF-alpha signaling pathway (WP231) WikiPathways WP231_r124583
Apoptosis modulation and signaling (WP1772) WikiPathways WP1772_r120736
Non-small cell lung cancer (WP4255) WikiPathways WP4255_r123348
Regucalcin in proximal tubule epithelial kidney cells (WP4838) WikiPathways WP4838_r110282
AGE/RAGE pathway (WP2324) WikiPathways WP2324_r120674
Endometrial cancer (WP4155) WikiPathways WP4155_r123347
miRNA regulation of DNA damage response (WP1530) WikiPathways WP1530_r124175
PI3K-Akt signaling pathway (WP4172) WikiPathways WP4172_r122580
Transcripts
Accession Version MolecularType Name NCBI Comments
NR_102733 2 miscRNA transcript variant 5 NC_000001 Reference
NR_102732 2 miscRNA transcript variant 4 NC_000001 Reference
XR_007064158 1 miscRNA transcript variant X4 NC_000001 Reference
XM_005246014 3 mRNA transcript variant X1 NC_000001 Reference
XM_047432034 1 mRNA transcript variant X2 NC_000001 Reference
NM_032996 3 mRNA transcript variant 3 NC_000001 Reference
NM_001278054 2 mRNA transcript variant beta NC_000001 Reference
NM_001229 5 mRNA transcript variant alpha NC_000001 Reference
XM_011542273 4 mRNA transcript variant X3 NC_000001 Reference