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TNFSF11

TNF superfamily member 11
General Information
Name TNF superfamily member 11
Alias
  • tumor necrosis factor ligand superfamily member 11
  • TNF-related activation-induced cytokine
  • osteoclast differentiation factor
  • osteoprotegerin ligand
  • receptor activator of nuclear factor kappa B ligand
  • tumor necrosis factor (ligand) superfamily, member 11
  • tumor necrosis factor ligand 6B
  • tumor necrosis factor superfamily member 11
Gene_family Tumor necrosis factor superfamily|CD molecules
organism Homo sapiens
entrez_id 8600
location 13q14
transcript_count 6
exon_count 10
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis. Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts. The deficient mice exhibited defects in early differentiation of T and B lymphocytes, and failed to form lobulo-alveolar mammary structures during pregnancy. Two alternatively spliced transcript variants have been found. [provided by RefSeq, Jul 2008]
    Stringdb Tumor necrosis factor ligand superfamily member 11; Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy. Induces osteoclastogenesis by activating multiple signaling pathways in osteoclast precu [...]
    nextProt Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy (PubMed:22664871). Induces osteoclastogenesis by activating multiple signaling pathways in osteoclast precursor cells, chief among which is induction of long lasting oscillations in the intracellular concentration of Ca (2+) resulting in the activation of NFATC1, which translocates to the nucleus and induces osteoclast-specific gene transcription to allow differentiation of osteoclasts. During osteoclast differentiation, in a TMEM64 and ATP2A2-dependent manner induces activation of CREB1 and mitochondrial ROS generation necessary for proper osteoclast generation (By similarity).
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
TNFSF11 BioGRID OAF GeneID BioGRID Affinity Capture-MS
TNFSF11 BioGRID ECHDC1 GeneID BioGRID Affinity Capture-MS
TNFSF11 BioGRID ZC3H3 GeneID BioGRID Affinity Capture-MS
TNFSF11 BioGRID GOSR1 GeneID BioGRID Affinity Capture-MS
TNFSF11 BioGRID TUBA1A GeneID BioGRID Affinity Capture-MS
TNFSF11 BioGRID SGCB GeneID BioGRID Affinity Capture-MS
TNFSF11 BioGRID ND1 GeneID BioGRID Affinity Capture-MS
TNFSF11 BioGRID DNAJB9 GeneID BioGRID Affinity Capture-MS
TNFSF11 BioGRID ATP5MC1 GeneID BioGRID Affinity Capture-MS
TNFSF11 BioGRID OLFM4 GeneID BioGRID Two-hybrid
TNFSF11 BioGRID UPK2 GeneID BioGRID Two-hybrid
TNFSF11 BioGRID RNF123 GeneID BioGRID Affinity Capture-MS
TNFSF11 BioGRID Pparg GeneID BioGRID Affinity Capture-MS
TNFSF11 BioGRID GALNT7 GeneID BioGRID Affinity Capture-MS
TNFSF11 BioGRID B4GALT7 GeneID BioGRID Affinity Capture-MS
TNFSF11 BioGRID PRXL2B GeneID BioGRID Two-hybrid
TNFSF11 BioGRID BBS10 GeneID BioGRID Two-hybrid
TNFSF11 BioGRID CEP126 GeneID BioGRID Two-hybrid
TNFSF11 BioGRID PHAX GeneID BioGRID Two-hybrid
TNFSF11 BioGRID ZC3HC1 GeneID BioGRID Two-hybrid
TNFSF11 BioGRID TMOD3 GeneID BioGRID Two-hybrid
TNFSF11 BioGRID TRMT2A GeneID BioGRID Two-hybrid
TNFSF11 BioGRID DDAH2 GeneID BioGRID Two-hybrid
TNFSF11 BioGRID SNRNP35 GeneID BioGRID Two-hybrid
TNFSF11 BioGRID MED24 GeneID BioGRID Two-hybrid
TNFSF11 BioGRID MBTPS1 GeneID BioGRID Two-hybrid
TNFSF11 BioGRID LMO4 GeneID BioGRID Two-hybrid
TNFSF11 BioGRID SBF1 GeneID BioGRID Two-hybrid
TNFSF11 BioGRID PLK1 GeneID BioGRID Two-hybrid
TNFSF11 BioGRID EZH2 GeneID BioGRID Two-hybrid
TNFSF11 BioGRID EEF1A1 GeneID BioGRID Two-hybrid
TNFSF11 Protein ADAM19 GeneID HPRD
TNFSF11 Protein ADAM17 GeneID HPRD
TNFSF11 Protein TNFRSF11A GeneID HPRD
TNFSF11 Protein TNFRSF11B GeneID HPRD
TNFSF11 Protein TNFSF11 GeneID HPRD
TNFSF11 Protein TRAF6 GeneID HPRD
TNFSF11 Protein MAPK3 GeneID HPRD
TNFSF11 Protein MAPK8 GeneID HPRD
TNFSF11 Protein MMP3 GeneID HPRD
TNFSF11 Protein MMP7 GeneID HPRD
TNFSF11 Protein MAPK1 GeneID HPRD
TNFSF11 Protein AKT1 GeneID HPRD
TNFSF11 Protein NFKB1 GeneID HPRD
TNFSF11 Protein NFKBIA GeneID HPRD
TNFSF11 Protein MMP1 GeneID HPRD
TNFSF11 BioGRID ZNF675 GeneID BioGRID Phenotypic Suppression
TNFSF11 BioGRID TNFRSF11B GeneID BioGRID Reconstituted Complex
TNFSF11 BioGRID SRC GeneID BioGRID Affinity Capture-Western
StringDB
A B experiments database textmining combined score hadb nhadb
TNFSF11 SPARC 0 0 529 548 1 2
TNFSF11 SMAD3 0 0 324 323 1 2
TNFSF11 BIRC3 0 600 177 669 1 1
TNFSF11 ANXA8 0 0 172 171 1 1
TNFSF11 PLS3 0 0 131 197 1 1
TNFSF11 FAM213A 0 0 158 157 1 1
TNFSF11 IL17F 0 0 391 392 1 1
TNFSF11 SERPINF1 0 0 166 165 1 1
TNFSF11 TNFRSF10A 0 0 471 471 1 1
TNFSF11 RNF123 270 0 0 270 1 1
TNFSF11 CNTF 0 0 97 188 1 1
TNFSF11 PDGFRB 0 0 234 234 1 2
TNFSF11 ENPP2 0 0 181 181 1 1
TNFSF11 LEF1 0 0 266 272 1 1
TNFSF11 ADIPOR1 0 0 233 232 1 1
TNFSF11 MARK3 0 0 245 244 1 1
TNFSF11 SIRPA 0 0 267 267 1 1
TNFSF11 EP300 0 0 181 181 1 2
TNFSF11 IL4 0 0 601 601 1 1
TNFSF11 WNT9B 0 0 263 263 1 1
TNFSF11 NOTCH3 0 0 203 212 1 1
TNFSF11 IL9 0 0 234 254 1 1
TNFSF11 ITGB1 0 0 320 334 1 1
TNFSF11 ITLN1 0 0 217 222 1 1
TNFSF11 HSPG2 0 0 142 165 1 1
TNFSF11 IL17RE 0 0 164 216 1 1
TNFSF11 TYROBP 0 0 556 559 1 1
TNFSF11 DSPP 0 0 213 213 1 1
TNFSF11 BBS10 55 0 0 159 1 1
TNFSF11 SFRP5 0 0 245 244 1 1
TNFSF11 IL16 0 0 205 222 1 1
TNFSF11 LEPR 0 0 321 321 1 1
TNFSF11 IDO1 0 0 150 198 1 1
TNFSF11 SNAI2 0 0 243 242 1 1
TNFSF11 CD276 0 0 310 309 1 1
TNFSF11 IFNE 0 0 95 162 1 1
TNFSF11 FAM3C 0 0 143 196 1 1
TNFSF11 CCL2 0 0 627 636 1 2
TNFSF11 KNG1 0 0 155 154 1 1
TNFSF11 CD68 0 0 456 456 1 2
TNFSF11 CASP8 0 0 305 310 1 2
TNFSF11 ALB 0 0 517 547 1 2
TNFSF11 IL1A 0 0 696 696 1 1
TNFSF11 CCL4 0 0 335 344 1 1
TNFSF11 CRYGC 0 0 170 169 1 1
TNFSF11 ACVR2B 0 0 181 181 1 1
TNFSF11 IAPP 0 0 181 181 1 2
TNFSF11 TRADD 0 0 218 218 1 1
TNFSF11 WNT1 0 0 407 407 1 2
TNFSF11 H3F3B 0 0 195 195 1 1
TNFSF11 GATA1 0 0 135 227 1 1
TNFSF11 PIK3R5 0 0 56 217 1 1
TNFSF11 EREG 0 0 160 159 1 1
TNFSF11 BSG 0 0 193 193 1 1
TNFSF11 DPP4 0 0 205 205 1 1
TNFSF11 CSN2 0 0 212 216 1 1
TNFSF11 FDCSP 0 0 193 193 1 1
TNFSF11 PDE4A 0 0 161 161 1 1
TNFSF11 MAF 0 0 267 267 1 1
TNFSF11 FNDC5 0 0 260 260 1 1
TNFSF11 PLG 0 0 242 241 1 1
TNFSF11 ALCAM 0 0 182 181 1 1
TNFSF11 CLCA4 0 0 0 438 1 1
TNFSF11 PDPN 0 0 392 393 1 1
TNFSF11 CDH1 0 0 370 370 1 2
TNFSF11 BMP7 0 0 505 505 1 1
TNFSF11 MFGE8 0 0 149 168 1 1
TNFSF11 GLI2 0 0 218 218 1 2
TNFSF11 PLA2G10 0 0 66 567 1 1
TNFSF11 AGER 0 0 234 234 1 2
TNFSF11 MATN1 0 0 107 171 1 1
TNFSF11 WNT16 0 0 450 450 1 1
TNFSF11 SIRT6 0 0 161 161 1 2
TNFSF11 FGF18 0 0 296 297 1 1
TNFSF11 CALCA 0 0 662 671 1 1
TNFSF11 ATP6V0D2 0 0 681 681 1 1
TNFSF11 ENO2 0 0 102 158 1 1
TNFSF11 VPS33A 0 0 436 436 1 1
TNFSF11 PTK2 0 0 316 325 1 2
TNFSF11 ADIPOQ 0 0 503 503 1 2
TNFSF11 FRZB 0 0 484 484 1 1
TNFSF11 GNPTAB 0 0 123 216 1 1
TNFSF11 MAPK8 213 0 455 552 1 2
TNFSF11 BMP1 0 0 261 261 1 1
TNFSF11 ARG1 0 0 246 245 1 2
TNFSF11 CSK 0 0 317 317 1 1
TNFSF11 ZNF467 0 0 125 179 1 1
TNFSF11 RAMP2 0 0 95 161 1 1
TNFSF11 CTGF 0 0 643 643 1 1
TNFSF11 P2RX7 0 0 243 264 1 2
TNFSF11 GPR56 0 0 48 152 1 1
TNFSF11 CCR1 0 0 370 383 1 1
TNFSF11 CISH 0 0 235 235 1 1
TNFSF11 PDGFA 0 0 166 165 1 1
TNFSF11 PTGER4 0 0 451 451 1 1
TNFSF11 IL2RG 0 0 130 202 1 1
TNFSF11 PRF1 0 0 182 181 1 1
TNFSF11 NR3C1 0 0 266 266 1 1
TNFSF11 IL1F10 0 0 174 421 1 1
TNFSF11 MMP16 0 0 95 271 1 1
TNFSF11 AMBN 0 0 245 244 1 1
TNFSF11 VR1 0 0 249 248 1 1
TNFSF11 NFIC 0 0 117 209 1 1
TNFSF11 HIST2H3PS2 0 0 240 239 1 1
TNFSF11 PXN 0 0 228 227 1 1
TNFSF11 CCR2 0 0 391 404 1 2
TNFSF11 MRC2 0 0 149 206 1 1
TNFSF11 ITGA1 0 0 147 175 1 1
TNFSF11 CEBPD 0 0 183 183 1 1
TNFSF11 NES 0 0 325 325 1 2
TNFSF11 RPTOR 0 0 112 167 1 2
TNFSF11 HSPB3 0 0 188 188 1 1
TNFSF11 PDCD4 0 0 219 219 1 2
TNFSF11 LPL 0 0 165 165 1 1
TNFSF11 TEK 0 0 269 269 1 1
TNFSF11 CXCL9 0 0 310 309 1 1
TNFSF11 MGME1 0 0 156 155 1 1
TNFSF11 PPARA 0 0 218 218 1 2
TNFSF11 GNAS 0 0 122 216 1 1
TNFSF11 CFD 0 0 155 154 1 1
TNFSF11 ACVR1 0 0 284 296 1 1
TNFSF11 HSPA4 0 0 160 159 1 1
TNFSF11 LIF 0 0 294 294 1 2
TNFSF11 IL12RB2 0 0 134 188 1 1
TNFSF11 DICER1 0 0 204 204 1 1
TNFSF11 CX3CR1 0 0 261 261 1 1
TNFSF11 EGF 0 0 420 424 1 2
TNFSF11 PRTN3 0 0 324 323 1 1
TNFSF11 UCMA 0 0 92 247 1 1
TNFSF11 CYP27A1 0 0 470 470 1 1
TNFSF11 BMP2 0 0 758 764 1 1
TNFSF11 PLAU 0 0 206 223 1 1
TNFSF11 IGFBP1 0 0 140 493 1 1
TNFSF11 IL17A 0 0 710 716 1 2
TNFSF11 OLFM4 246 0 0 245 1 1
TNFSF11 ETS1 0 0 142 178 1 1
TNFSF11 GDF2 0 0 300 300 1 1
TNFSF11 POMC 0 0 246 245 1 1
TNFSF11 TRAF6 213 900 988 999 1 2
TNFSF11 CASP9 0 0 246 245 1 2
TNFSF11 NANOG 0 0 166 165 1 2
TNFSF11 MAPK9 0 0 218 218 1 2
TNFSF11 TAF8 0 0 282 295 1 1
TNFSF11 CXCL11 0 0 218 236 1 1
TNFSF11 TLR7 0 0 246 265 1 2
TNFSF11 CYCS 0 0 218 218 1 2
TNFSF11 NRP1 0 0 231 230 1 1
TNFSF11 VWA8 0 0 47 150 1 1
TNFSF11 CAV1 0 0 185 185 1 2
TNFSF11 TNFSF10 0 0 566 205 1 2
TNFSF11 HLA-DRB1 0 0 206 206 1 1
TNFSF11 PADI4 0 0 181 181 1 1
TNFSF11 JAK3 0 0 204 205 1 1
TNFSF11 MAP2K3 0 0 247 262 1 1
TNFSF11 CXCL6 0 0 135 169 1 1
TNFSF11 DNTT 0 0 203 203 1 1
TNFSF11 CD74 0 0 155 154 1 1
TNFSF11 CD27 0 0 287 302 1 1
TNFSF11 MDFI 0 0 52 322 1 1
TNFSF11 RYK 0 0 144 166 1 1
TNFSF11 CASP1 0 0 285 284 1 2
TNFSF11 CCR3 0 0 206 223 1 1
TNFSF11 PLCG1 0 0 241 241 1 1
TNFSF11 NRG3 0 0 84 183 1 1
TNFSF11 JUN 0 0 617 626 1 2
TNFSF11 MAFB 0 0 401 400 1 1
TNFSF11 FZD1 0 0 181 186 1 1
TNFSF11 TYK2 0 0 166 165 1 1
TNFSF11 MEX3D 0 0 0 186 1 1
TNFSF11 DLL4 0 0 181 181 1 1
TNFSF11 GZMA 0 0 134 268 1 1
TNFSF11 IL10RA 0 0 142 165 1 1
TNFSF11 CDH17 0 0 182 181 1 1
TNFSF11 TNKS 0 0 142 165 1 1
TNFSF11 ITGAL 0 0 194 194 1 1
TNFSF11 BCL2L11 0 0 284 284 1 2
TNFSF11 SERPINB2 0 0 112 167 1 1
TNFSF11 ENSG00000173366 0 0 325 339 1 1
TNFSF11 CYP19A1 0 0 455 455 1 2
TNFSF11 KL 0 0 401 400 1 2
TNFSF11 CALB1 0 0 88 294 1 1
TNFSF11 SIGLEC1 0 0 202 202 1 1
TNFSF11 CCL24 0 0 135 192 1 1
TNFSF11 LTA 0 600 391 818 1 1
TNFSF11 CD69 0 0 261 261 1 1
TNFSF11 IL37 0 0 160 350 1 1
TNFSF11 CCR5 0 0 335 349 1 1
TNFSF11 IL36RN 0 0 119 469 1 1
TNFSF11 DNAJC3 0 0 0 200 1 1
TNFSF11 IL7R 0 0 334 350 1 1
TNFSF11 SHH 0 0 206 206 1 2
TNFSF11 FGF6 0 0 54 205 1 1
TNFSF11 DCSTAMP 0 0 806 827 1 1
TNFSF11 SPTBN1 0 0 183 183 1 1
TNFSF11 COMP 0 0 325 332 1 1
TNFSF11 FYN 0 0 161 161 1 1
TNFSF11 IGFBP4 0 0 137 155 1 1
TNFSF11 NFKBIE 0 0 202 251 1 1
TNFSF11 GRB2 0 0 214 295 1 1
TNFSF11 FDPS 0 0 451 451 1 1
TNFSF11 FST 0 0 195 195 1 1
TNFSF11 CCRL2 0 0 391 390 1 1
TNFSF11 IL17RA 0 0 392 392 1 1
TNFSF11 HIVEP3 0 0 243 242 1 1
TNFSF11 LCK 0 0 247 338 1 1
TNFSF11 IFNK 0 0 95 186 1 1
TNFSF11 TDRD3 0 0 0 189 1 1
TNFSF11 JAG1 0 0 422 428 1 1
TNFSF11 NFATC3 0 0 187 192 1 1
TNFSF11 TCF7 0 0 194 211 1 1
TNFSF11 CNR2 0 0 325 325 1 1
TNFSF11 ANGPT2 0 0 181 190 1 1
TNFSF11 SLC36A2 0 0 0 626 1 1
TNFSF11 TNFSF4 0 0 406 406 1 1
TNFSF11 OSTF1 0 0 81 239 1 1
TNFSF11 TNFRSF8 0 0 244 271 1 1
TNFSF11 KRT8 0 0 157 156 1 1
TNFSF11 TCIRG1 0 0 613 616 1 1
TNFSF11 TNFRSF13C 0 600 321 722 1 1
TNFSF11 SLAMF1 0 0 203 218 1 1
TNFSF11 TREM2 0 0 460 463 1 1
TNFSF11 RUNX3 0 0 161 161 1 1
TNFSF11 MMP2 0 0 469 479 1 2
TNFSF11 TBXAS1 0 0 481 481 1 1
TNFSF11 LRRC32 0 0 48 150 1 1
TNFSF11 IGFBP3 0 0 260 260 1 2
TNFSF11 RAB27A 0 0 150 214 1 1
TNFSF11 OSCAR 0 0 685 739 1 1
TNFSF11 DLL1 0 0 172 171 1 1
TNFSF11 CHST3 0 0 49 211 1 1
TNFSF11 SMAD1 0 0 171 243 1 2
TNFSF11 BMP6 0 0 423 422 1 1
TNFSF11 CD8A 0 0 519 519 1 1
TNFSF11 ADAM8 0 0 235 235 1 1
TNFSF11 IL36A 0 0 82 446 1 1
TNFSF11 TIMP1 0 0 393 392 1 1
TNFSF11 PLXNA1 0 0 162 161 1 1
TNFSF11 FGF4 0 0 57 201 1 1
TNFSF11 GPR29 0 0 401 422 1 1
TNFSF11 CXCL12 0 0 596 596 1 2
TNFSF11 CCL18 0 0 203 214 1 1
TNFSF11 TLR5 0 0 218 235 1 1
TNFSF11 PLA2G1B 0 0 145 180 1 1
TNFSF11 KLRK1 0 0 171 171 1 1
TNFSF11 CD1C 0 0 242 241 1 1
TNFSF11 GNRH1 0 0 260 260 1 1
TNFSF11 RHOA 0 0 361 361 1 2
TNFSF11 AR 0 0 377 377 1 2
TNFSF11 FGL2 0 0 105 580 1 1
TNFSF11 GDF10 0 0 181 215 1 1
TNFSF11 EPCAM 0 0 254 254 1 2
TNFSF11 GSN 0 0 181 181 1 1
TNFSF11 CDKN1A 0 0 170 169 1 2
TNFSF11 SPP1 0 0 748 755 1 2
TNFSF11 TNFRSF14 0 0 293 304 1 1
TNFSF11 ICAM1 0 0 576 576 1 2
TNFSF11 PTGER2 0 0 108 163 1 1
TNFSF11 IL22 0 0 391 413 1 1
TNFSF11 GALNT3 0 0 248 248 1 1
TNFSF11 MS4A1 0 0 101 150 1 1
TNFSF11 SOX9 0 0 426 431 1 1
TNFSF11 CD24 0 0 261 261 1 2
TNFSF11 ZEB1 0 0 184 183 1 2
TNFSF11 PTPRC 0 0 505 517 1 1
TNFSF11 PRG4 0 0 210 210 1 1
TNFSF11 OMD 0 0 146 166 1 1
TNFSF11 SOST 0 0 859 865 1 1
TNFSF11 CXCR1 0 0 240 239 1 1
TNFSF11 ESR2 0 0 450 451 1 1
TNFSF11 ITGAV 0 0 518 518 1 1
TNFSF11 CYP2R1 0 0 185 185 1 1
TNFSF11 IGFBP2 0 0 170 221 1 1
TNFSF11 SEMA4A 0 0 180 179 1 1
TNFSF11 CRP 0 0 549 549 1 2
TNFSF11 SOX2 0 0 166 165 1 2
TNFSF11 CEBPA 0 0 293 293 1 1
TNFSF11 CLEC2D 0 0 234 234 1 1
TNFSF11 RGS12 0 0 213 213 1 1
TNFSF11 HPGDS 0 0 241 240 1 1
TNFSF11 IL21 0 0 127 512 1 1
TNFSF11 SP7 0 0 758 779 1 1
TNFSF11 HDAC4 0 0 246 245 1 2
TNFSF11 PRRX1 0 0 204 291 1 1
TNFSF11 IL3 0 0 629 637 1 1
TNFSF11 LTB 0 600 323 758 1 1
TNFSF11 FOSL1 0 0 323 323 1 1
TNFSF11 TFEB 0 0 153 152 1 2
TNFSF11 HSP90AA1 0 0 217 217 1 2
TNFSF11 PDGFD 0 0 103 202 1 1
TNFSF11 JUNB 0 0 204 204 1 1
TNFSF11 FCGR2B 0 0 261 261 1 1
TNFSF11 SQSTM1 0 0 324 323 1 2
TNFSF11 VSIG2 0 0 0 248 1 1
TNFSF11 NAA15 0 0 0 190 1 1
TNFSF11 MAPK3 213 0 517 606 1 2
TNFSF11 KEAP1 0 0 180 179 1 2
TNFSF11 PAX5 0 0 193 193 1 1
TNFSF11 MMP9 0 0 709 722 1 2
TNFSF11 B2M 0 0 325 326 1 1
TNFSF11 THY1 0 0 324 323 1 1
TNFSF11 ANGPT1 0 0 261 269 1 1
TNFSF11 PROM1 0 0 182 181 1 2
TNFSF11 SELL 0 0 242 258 1 1
TNFSF11 RPS2 0 0 213 222 1 1
TNFSF11 FPR2 0 0 154 153 1 1
TNFSF11 FGF1 0 0 181 181 1 1
TNFSF11 WNT6 0 0 289 288 1 1
TNFSF11 CD40 0 600 556 817 1 2
TNFSF11 CTTN 0 0 167 167 1 1
TNFSF11 ACTB 0 0 606 645 1 2
TNFSF11 SNX10 0 0 371 423 1 2
TNFSF11 GAS6 0 0 179 179 1 1
TNFSF11 INS 0 0 519 519 1 2
TNFSF11 SELP 0 0 166 180 1 1
TNFSF11 IL17B 0 0 249 248 1 1
TNFSF11 ADAMTS5 0 0 324 335 1 1
TNFSF11 CXCR2 0 0 271 281 1 1
TNFSF11 PMM1 0 0 42 172 1 1
TNFSF11 MYOM2 0 0 188 188 1 1
TNFSF11 C3AR1 0 0 213 213 1 1
TNFSF11 WNT2B 0 0 261 425 1 1
TNFSF11 TNFRSF1B 0 600 324 718 1 1
TNFSF11 IGSF23 0 0 74 215 1 1
TNFSF11 B7RP1 0 0 184 183 1 1
TNFSF11 SPERT 0 0 52 153 1 1
TNFSF11 HRAS 0 0 210 264 1 2
TNFSF11 FCGR3A 0 0 315 315 1 1
TNFSF11 CTNNB1 0 0 749 756 1 2
TNFSF11 OSTM1 0 0 517 517 1 1
TNFSF11 ATP6V1B1 0 0 57 156 1 1
TNFSF11 CDK2 0 0 161 161 1 2
TNFSF11 EGR1 0 0 193 193 1 2
TNFSF11 DCAF6 0 0 234 234 1 1
TNFSF11 UPK2 245 0 0 244 1 1
TNFSF11 EPHA2 0 0 183 183 1 1
TNFSF11 FCRL4 0 0 213 232 1 1
TNFSF11 TRPV1 0 0 249 248 1 2
TNFSF11 ID1 0 0 164 163 1 1
TNFSF11 RNF11 0 0 56 155 1 1
TNFSF11 CXCL8 0 0 616 624 1 2
TNFSF11 KLK3 0 0 391 390 1 1
TNFSF11 NCR1 0 0 166 165 1 1
TNFSF11 WNT7A 0 0 261 261 1 1
TNFSF11 IL6R 0 0 370 370 1 1
TNFSF11 CTSL 0 0 193 201 1 2
TNFSF11 NFKBID 0 0 134 229 1 1
TNFSF11 PRKCB 0 0 184 183 1 2
TNFSF11 WNT7B 0 0 315 315 1 1
TNFSF11 TRAF5 0 0 468 468 1 1
TNFSF11 POSTN 0 0 390 403 1 1
TNFSF11 EDN1 0 0 391 390 1 1
TNFSF11 HIF1A 0 0 427 426 1 2
TNFSF11 ATP6V1H 0 0 81 276 1 1
TNFSF11 SMAD9 0 0 160 159 1 1
TNFSF11 CYP27B1 0 0 415 419 1 1
TNFSF11 ZFP64 0 0 306 306 1 1
TNFSF11 SMPD3 0 0 134 396 1 1
TNFSF11 KREMEN2 0 0 193 194 1 1
TNFSF11 IL1B 0 0 861 861 1 2
TNFSF11 MATN4 0 0 57 305 1 1
TNFSF11 VAV3 0 0 325 331 1 1
TNFSF11 LGR4 0 0 985 985 1 1
TNFSF11 SOCS5 0 0 155 154 1 1
TNFSF11 H3F3A 0 0 204 204 1 1
TNFSF11 STAT1 0 0 393 418 1 2
TNFSF11 ART1 0 0 0 188 1 1
TNFSF11 GZMB 0 0 188 273 1 1
TNFSF11 TNFRSF1A 0 0 880 883 1 1
TNFSF11 PLEK 0 0 160 181 1 1
TNFSF11 OCLN 0 0 92 296 1 1
TNFSF11 IL17D 0 0 158 165 1 1
TNFSF11 MPO 0 0 323 323 1 2
TNFSF11 ACAN 0 0 406 423 1 1
TNFSF11 ETS2 0 0 91 186 1 1
TNFSF11 CXCL14 0 0 74 183 1 1
TNFSF11 CTRL 0 0 167 167 1 2
TNFSF11 LYZ 0 0 120 232 1 1
TNFSF11 LYVE1 0 0 181 181 1 1
TNFSF11 IL6 0 0 802 812 1 2
TNFSF11 RHOU 0 0 155 154 1 1
TNFSF11 MTOR 0 0 334 334 1 2
TNFSF11 TRPV6 0 0 371 372 1 1
TNFSF11 POTEF 0 0 240 316 1 1
TNFSF11 BMP3 0 0 252 252 1 1
TNFSF11 SAA1 0 0 173 173 1 1
TNFSF11 CD163 0 0 293 293 1 1
TNFSF11 TRAF4 0 0 395 394 1 1
TNFSF11 CYR61 0 0 184 183 1 1
TNFSF11 CXCR4 0 0 619 621 1 2
TNFSF11 FGF13 0 0 371 371 1 1
TNFSF11 ENTPD1 0 0 163 252 1 1
TNFSF11 MMP1 213 0 504 593 1 1
TNFSF11 NOTCH1 0 0 460 466 1 2
TNFSF11 CD40LG 0 600 602 703 1 1
TNFSF11 PTGS1 0 0 141 159 1 1
TNFSF11 SH3BP2 0 0 456 456 1 1
TNFSF11 KREMEN1 0 0 135 154 1 1
TNFSF11 PHEX 0 0 518 518 1 1
TNFSF11 IL4R 0 0 170 188 1 1
TNFSF11 CA2 0 0 603 605 1 1
TNFSF11 PTGER1 0 0 233 232 1 1
TNFSF11 WNT11 0 0 268 268 1 1
TNFSF11 TNFSF18 0 0 320 319 1 1
TNFSF11 CXCL13 0 0 470 498 1 1
TNFSF11 C5AR1 0 0 246 245 1 1
TNFSF11 TNFSF9 0 0 360 360 1 1
TNFSF11 EPO 0 0 220 220 1 2
TNFSF11 ANXA5 0 0 374 374 1 2
TNFSF11 WNT8A 0 0 261 261 1 1
TNFSF11 TNFSF13 0 0 287 286 1 1
TNFSF11 OSMR 0 0 156 155 1 1
TNFSF11 FGF21 0 0 193 273 1 2
TNFSF11 LMAN1 0 0 0 206 1 1
TNFSF11 NRG2 0 0 45 150 1 1
TNFSF11 PERP 0 0 52 153 1 1
TNFSF11 IL2RB 0 0 162 219 1 1
TNFSF11 BIRC2 0 600 261 691 1 1
TNFSF11 IFNG 0 0 576 611 1 2
TNFSF11 STARD3NL 0 0 193 193 1 1
TNFSF11 APC 0 0 141 162 1 1
TNFSF11 CCL5 0 0 464 463 1 2
TNFSF11 TGFB3 0 0 289 288 1 1
TNFSF11 PLCG2 0 0 556 565 1 1
TNFSF11 TNFRSF17 0 0 184 183 1 1
TNFSF11 TWSG1 0 0 155 240 1 1
TNFSF11 CREB1 0 0 459 459 1 2
TNFSF11 HCST 0 0 123 187 1 1
TNFSF11 CCL13 0 0 146 182 1 1
TNFSF11 SIRPB1 0 0 390 390 1 1
TNFSF11 CYP17A1 0 0 195 195 1 1
TNFSF11 CALB2 0 0 0 258 1 1
TNFSF11 RSPO2 0 0 134 198 1 1
TNFSF11 ESRRA 0 0 207 213 1 1
TNFSF11 SDHB 0 0 155 154 1 1
TNFSF11 GDF9 0 0 67 151 1 1
TNFSF11 IGFBP5 0 0 180 179 1 1
TNFSF11 CD83 0 0 220 220 1 1
TNFSF11 CD14 0 0 72 233 1 1
TNFSF11 TNFSF15 0 0 324 205 1 1
TNFSF11 RAP1A 0 0 134 166 1 1
TNFSF11 SLC20A2 0 0 150 177 1 1
TNFSF11 JAG2 0 0 174 183 1 1
TNFSF11 ABL1 0 0 167 167 1 1
TNFSF11 MAP2K7 0 0 369 369 1 1
TNFSF11 NOS2 0 0 172 184 1 2
TNFSF11 CD1A 0 0 228 227 1 1
TNFSF11 CX3CL1 0 0 283 284 1 1
TNFSF11 EMR1 0 0 0 208 1 1
TNFSF11 SMAD2 0 0 391 390 1 2
TNFSF11 TLR4 0 0 509 519 1 2
TNFSF11 CD22 0 0 107 153 1 1
TNFSF11 FGFR2 0 0 204 205 1 1
TNFSF11 TNFRSF25 0 0 218 235 1 1
TNFSF11 HEYL 0 0 136 175 1 1
TNFSF11 GAPDH 0 0 637 637 1 2
TNFSF11 GREM1 0 0 193 193 1 1
TNFSF11 NFKB1 213 0 282 472 1 2
TNFSF11 BCL2L1 0 0 369 369 1 2
TNFSF11 ENSG00000026036 0 0 324 323 1 1
TNFSF11 RELA 0 0 460 474 1 2
TNFSF11 AOC3 0 0 152 151 1 1
TNFSF11 CCL4L1 0 0 245 256 1 1
TNFSF11 EMCN 0 0 180 186 1 1
TNFSF11 ELF5 0 0 294 302 1 1
TNFSF11 WIF1 0 0 252 252 1 1
TNFSF11 KITLG 0 0 338 338 1 1
TNFSF11 S100G 0 0 219 232 1 1
TNFSF11 CALCR 0 0 800 805 1 1
TNFSF11 AMELX 0 0 229 228 1 1
TNFSF11 ZAP70 0 0 180 197 1 1
TNFSF11 MMP20 0 0 57 362 1 1
TNFSF11 TLR10 0 0 124 286 1 1
TNFSF11 ACKR4 0 0 162 161 1 1
TNFSF11 ITGA4 0 0 167 167 1 1
TNFSF11 STAT4 0 0 145 316 1 1
TNFSF11 RARG 0 0 0 190 1 1
TNFSF11 GAB2 0 0 393 393 1 1
TNFSF11 IL27RA 0 0 134 167 1 1
TNFSF11 SBNO2 0 0 124 188 1 1
TNFSF11 PIK3CA 0 0 134 152 1 2
TNFSF11 MMP17 0 0 0 351 1 1
TNFSF11 IL2RA 0 0 210 224 1 1
TNFSF11 ARHGAP1 0 0 183 183 1 1
TNFSF11 ACP5 0 0 915 916 1 1
TNFSF11 MX1 0 0 186 187 1 1
TNFSF11 IBSP 0 0 687 692 1 1
TNFSF11 TRAF2 0 600 645 852 1 2
TNFSF11 TAB1 0 0 314 313 1 1
TNFSF11 NOG 0 0 413 412 1 1
TNFSF11 SEMA6A 0 0 151 150 1 1
TNFSF11 DVL1 0 0 161 177 1 1
TNFSF11 GNAQ 0 0 210 210 1 1
TNFSF11 TAB2 0 0 358 358 1 2
TNFSF11 IL36G 0 0 0 299 1 1
TNFSF11 SDHC 0 0 262 262 1 1
TNFSF11 IGF1R 0 0 324 323 1 2
TNFSF11 SLAMF7 0 0 150 191 1 1
TNFSF11 FGF10 0 0 119 181 1 1
TNFSF11 TNFRSF6B 0 0 324 323 1 1
TNFSF11 TREM1 0 0 142 160 1 1
TNFSF11 PPARGC1A 0 0 174 173 1 2
TNFSF11 ADAM10 0 0 186 186 1 1
TNFSF11 HPSE 0 0 167 186 1 1
TNFSF11 TPH1 0 0 170 169 1 1
TNFSF11 RGS10 0 0 432 432 1 1
TNFSF11 MATN2 0 0 140 584 1 1
TNFSF11 CBLB 0 0 0 227 1 1
TNFSF11 IL1R1 0 0 403 403 1 1
TNFSF11 IL15 0 0 454 466 1 1
TNFSF11 MYC 0 0 391 390 1 2
TNFSF11 ITGAE 0 0 202 264 1 1
TNFSF11 IL18 0 0 469 469 1 2
TNFSF11 WNT5A 0 0 457 469 1 2
TNFSF11 IFNA1 0 0 325 325 1 1
TNFSF11 CD80 0 0 423 448 1 2
TNFSF11 PDGFB 0 0 167 167 1 2
TNFSF11 CCL21 0 0 416 416 1 1
TNFSF11 BRCA1 0 0 299 299 1 2
TNFSF11 SSR1 0 0 0 211 1 1
TNFSF11 AREG 0 0 392 414 1 1
TNFSF11 NPY 0 0 193 193 1 1
TNFSF11 FURIN 0 0 125 161 1 1
TNFSF11 OSM 0 0 451 451 1 1
TNFSF11 MAP2K1 0 0 261 261 1 1
TNFSF11 NFE2L2 0 0 246 245 1 2
TNFSF11 TLR1 0 0 224 292 1 1
TNFSF11 OGN 0 0 193 193 1 1
TNFSF11 CLEC1B 0 0 94 164 1 1
TNFSF11 AKT2 0 0 142 160 1 2
TNFSF11 RPS19 0 0 240 239 1 1
TNFSF11 IL17RC 0 0 275 275 1 1
TNFSF11 TNFRSF13B 0 0 275 282 1 1
TNFSF11 NELFCD 0 0 160 159 1 1
TNFSF11 LY75 0 0 172 190 1 1
TNFSF11 CHI3L1 0 0 211 211 1 1
TNFSF11 LAG3 0 0 150 184 1 1
TNFSF11 SMAD4 0 0 325 325 1 2
TNFSF11 LRP5 0 0 681 712 1 1
TNFSF11 TNFRSF12A 0 600 222 675 1 1
TNFSF11 DLX2 0 0 61 154 1 1
TNFSF11 S1PR2 0 0 177 177 1 1
TNFSF11 HDAC5 0 0 176 194 1 1
TNFSF11 INHBA 0 0 150 188 1 1
TNFSF11 DDIT3 0 0 123 173 1 2
TNFSF11 MAP3K7 0 0 321 321 1 2
TNFSF11 WNT4 0 0 491 502 1 1
TNFSF11 LCP2 0 0 142 327 1 1
TNFSF11 TNFRSF11B 967 800 990 999 1 1
TNFSF11 IRAK1 0 0 386 386 1 1
TNFSF11 NCOR2 0 0 90 152 1 1
TNFSF11 PSTPIP2 0 0 161 218 1 1
TNFSF11 CSF3 0 0 425 429 1 1
TNFSF11 ADAMTS1 0 0 204 240 1 1
TNFSF11 GZMH 0 0 0 303 1 1
TNFSF11 FGF7 0 0 166 188 1 1
TNFSF11 FAM210A 0 0 171 171 1 1
TNFSF11 CAMP 0 0 218 218 1 2
TNFSF11 TRAF1 0 0 454 454 1 1
TNFSF11 DOK3 0 0 124 153 1 1
TNFSF11 FFAR1 0 0 108 174 1 1
TNFSF11 FADD 0 0 171 171 1 2
TNFSF11 FGFR3 0 0 237 237 1 1
TNFSF11 TSLP 0 0 181 181 1 1
TNFSF11 PSTPIP1 0 0 155 175 1 1
TNFSF11 CFLAR 0 0 211 211 1 2
TNFSF11 EGFR 0 0 392 392 1 2
TNFSF11 CDK4 0 0 184 183 1 2
TNFSF11 ADORA3 0 0 161 161 1 1
TNFSF11 TNFRSF4 0 0 324 339 1 1
TNFSF11 MYD88 0 0 372 372 1 2
TNFSF11 DCN 0 0 241 240 1 2
TNFSF11 MDM2 0 0 173 173 1 2
TNFSF11 LCN2 0 0 219 219 1 1
TNFSF11 TP53 0 0 396 397 1 2
TNFSF11 TGM2 0 0 181 181 1 2
TNFSF11 B4GALT7 248 0 0 248 1 1
TNFSF11 IL20RA 0 0 184 217 1 1
TNFSF11 SATB2 0 0 175 175 1 1
TNFSF11 TGFA 0 0 154 206 1 1
TNFSF11 ZNF675 209 0 50 216 1 1
TNFSF11 PTPN22 0 0 193 228 1 1
TNFSF11 SEMA3B 0 0 167 167 1 1
TNFSF11 RAB9A 0 0 0 207 1 2
TNFSF11 EZH2 63 0 181 199 1 2
TNFSF11 GALNT7 169 0 0 169 1 1
TNFSF11 STAT3 0 0 518 531 1 2
TNFSF11 DKK2 0 0 266 266 1 1
TNFSF11 HBEGF 0 0 252 252 1 1
TNFSF11 SLC13A5 0 0 0 190 1 1
TNFSF11 LRRC17 0 0 166 165 1 1
TNFSF11 SLC9B2 0 0 245 244 1 1
TNFSF11 KRT5 0 0 193 193 1 1
TNFSF11 GATA3 0 0 306 312 1 1
TNFSF11 MMP15 0 0 47 356 1 1
TNFSF11 CEMP1 0 0 194 194 1 1
TNFSF11 CCL25 0 0 154 153 1 1
TNFSF11 ANKH 0 0 234 234 1 1
TNFSF11 SEMA3D 0 0 193 193 1 1
TNFSF11 CAMKK2 0 0 167 167 1 2
TNFSF11 CLU 0 0 108 169 1 2
TNFSF11 KLF10 0 0 194 194 1 1
TNFSF11 TSC22D3 0 0 161 161 1 1
TNFSF11 WNT5B 0 0 338 353 1 1
TNFSF11 GHRL 0 0 181 181 1 1
TNFSF11 COL2A1 0 0 383 444 1 2
TNFSF11 JAK2 0 0 365 365 1 2
TNFSF11 PTX3 0 0 193 193 1 1
TNFSF11 CDH2 0 0 315 315 1 1
TNFSF11 HDAC6 0 0 151 162 1 2
TNFSF11 KERA 0 0 141 165 1 1
TNFSF11 BMP4 0 0 470 470 1 1
TNFSF11 MAP3K3 0 0 165 165 1 1
TNFSF11 NFKBIA 213 0 650 714 1 2
TNFSF11 KIT 0 0 391 390 1 2
TNFSF11 SYK 0 0 459 462 1 2
TNFSF11 LEP 0 0 658 658 1 1
TNFSF11 S1PR1 0 0 136 178 1 1
TNFSF11 MAPK14 0 0 315 434 1 2
TNFSF11 TIMP3 0 0 218 218 1 1
TNFSF11 IL21R 0 0 126 157 1 1
TNFSF11 TNFRSF9 0 0 322 321 1 1
TNFSF11 RORC 0 0 285 329 1 1
TNFSF11 PTH2R 0 0 90 230 1 1
TNFSF11 FCGR2A 0 0 235 236 1 1
TNFSF11 UCP1 0 0 144 162 1 2
TNFSF11 NGFR 0 0 160 159 1 1
TNFSF11 CD79A 0 0 113 156 1 1
TNFSF11 PTH1R 0 0 604 622 1 1
TNFSF11 TNFRSF11A 698 900 985 999 1 1
TNFSF11 VEGFA 0 0 728 728 1 2
TNFSF11 GC 0 0 241 240 1 1
TNFSF11 GPR68 0 0 297 297 1 1
TNFSF11 IRF4 0 0 241 266 1 1
TNFSF11 NFIA 0 0 233 232 1 1
TNFSF11 BMPR1A 0 0 264 342 1 1
TNFSF11 FOXL1 0 0 150 181 1 1
TNFSF11 PTEN 0 0 295 295 1 2
TNFSF11 EDIL3 0 0 181 181 1 1
TNFSF11 FCER1G 0 0 322 400 1 1
TNFSF11 TRAF7 0 0 400 400 1 1
TNFSF11 GAPDHS 0 0 0 298 1 1
TNFSF11 MYOD1 0 0 113 193 1 1
TNFSF11 NFATC1 0 0 874 887 1 2
TNFSF11 CD200 0 0 260 260 1 1
TNFSF11 MMP11 0 0 89 250 1 1
TNFSF11 COL10A1 0 0 298 298 1 1
TNFSF11 FFAR4 0 0 136 154 1 1
TNFSF11 FOSB 0 0 171 185 1 1
TNFSF11 ATG7 0 0 166 165 1 2
TNFSF11 WNT10A 0 0 269 274 1 1
TNFSF11 GDF5 0 0 204 204 1 1
TNFSF11 CDH11 0 0 325 325 1 1
TNFSF11 TAC1 0 0 234 234 1 1
TNFSF11 SELE 0 0 261 274 1 1
TNFSF11 TGFBR2 0 0 207 207 1 1
TNFSF11 RPL38 0 0 124 164 1 1
TNFSF11 CCL23 0 0 168 187 1 1
TNFSF11 PSMB11 0 0 150 186 1 1
TNFSF11 ACTG1 0 0 235 268 1 1
TNFSF11 HIVEP2 0 0 125 159 1 1
TNFSF11 GDF15 0 0 232 231 1 1
TNFSF11 FOSL2 0 0 359 359 1 1
TNFSF11 IKZF1 0 0 123 179 1 1
TNFSF11 EFNB2 0 0 451 451 1 1
TNFSF11 CCL20 0 0 551 561 1 1
TNFSF11 SNAI1 0 0 294 294 1 1
TNFSF11 IL10 0 0 614 626 1 2
TNFSF11 CXCR6 0 0 205 243 1 1
TNFSF11 COL1A1 0 0 596 604 1 2
TNFSF11 CXCL2 0 0 320 352 1 1
TNFSF11 IRAK4 0 0 166 165 1 1
TNFSF11 RBPJ 0 0 321 321 1 1
TNFSF11 FLT3 0 0 236 236 1 2
TNFSF11 NAMPT 0 0 210 210 1 2
TNFSF11 PPARGC1B 0 0 219 297 1 1
TNFSF11 AXIN1 0 0 292 292 1 1
TNFSF11 CTSD 0 0 150 169 1 2
TNFSF11 IL23A 0 0 250 250 1 1
TNFSF11 IGF2 0 0 300 308 1 1
TNFSF11 TNFRSF10C 0 0 265 265 1 1
TNFSF11 ITGA2B 0 0 113 150 1 1
TNFSF11 TMEM64 0 0 247 274 1 1
TNFSF11 SHC1 0 0 180 179 1 1
TNFSF11 SFRP1 0 0 835 835 1 1
TNFSF11 SMAD5 0 0 323 339 1 1
TNFSF11 FCGR3B 0 0 298 298 1 1
TNFSF11 CCL22 0 0 294 309 1 1
TNFSF11 SEMA3E 0 0 161 161 1 1
TNFSF11 CCL3 0 0 557 563 1 1
TNFSF11 CTSG 0 0 212 275 1 1
TNFSF11 ENG 0 0 322 321 1 2
TNFSF11 PRKCA 0 0 154 153 1 1
TNFSF11 ATP5G1 279 0 0 284 1 1
TNFSF11 THPO 0 0 182 181 1 1
TNFSF11 KLHL42 0 0 109 194 1 1
TNFSF11 NCAM1 0 0 217 217 1 1
TNFSF11 DNAJC15 0 0 0 299 1 1
TNFSF11 TBX21 0 0 294 309 1 1
TNFSF11 ATP6AP1 0 0 164 189 1 1
TNFSF11 GPX1 0 0 150 184 1 1
TNFSF11 CCR7 0 0 338 352 1 1
TNFSF11 RAG2 0 0 150 168 1 1
TNFSF11 IKBKG 0 0 451 451 1 1
TNFSF11 CCR9 0 0 134 165 1 1
TNFSF11 VTN 0 0 375 375 1 1
TNFSF11 TBP 0 0 146 231 1 1
TNFSF11 CASR 0 0 530 539 1 2
TNFSF11 FN1 0 0 460 459 1 2
TNFSF11 CXCR5 0 0 344 360 1 1
TNFSF11 MMP13 0 0 611 643 1 2
TNFSF11 TGFBR1 0 0 234 249 1 1
TNFSF11 CTHRC1 0 0 261 262 1 1
TNFSF11 S100A4 0 0 194 194 1 1
TNFSF11 IL22RA1 0 0 236 236 1 1
TNFSF11 HSPB2 0 0 156 155 1 1
TNFSF11 ADAM19 213 0 150 302 1 1
TNFSF11 HSPB1 0 0 164 163 1 2
TNFSF11 GLI1 0 0 235 235 1 2
TNFSF11 ENSG00000255819 0 0 171 171 1 1
TNFSF11 ADRB1 0 0 112 155 1 1
TNFSF11 VAV1 0 0 210 225 1 1
TNFSF11 LAMC3 0 0 301 301 1 1
TNFSF11 RIN3 0 0 150 206 1 1
TNFSF11 FAM20C 0 0 103 256 1 1
TNFSF11 TIMP2 0 0 271 271 1 1
TNFSF11 CD1E 0 0 229 228 1 1
TNFSF11 ISG15 0 0 96 169 1 2
TNFSF11 CALCRL 0 0 165 226 1 1
TNFSF11 MCAM 0 0 243 242 1 1
TNFSF11 XCL1 0 0 134 184 1 1
TNFSF11 AGFG1 0 0 143 161 1 1
TNFSF11 SERPINB5 0 0 390 390 1 1
TNFSF11 PIAS3 0 0 164 163 1 1
TNFSF11 EFNA2 0 0 253 252 1 1
TNFSF11 SPHK1 0 0 244 253 1 2
TNFSF11 ADAM17 213 0 324 445 1 1
TNFSF11 NFKBIB 0 0 240 317 1 1
TNFSF11 PLXNB1 0 0 166 165 1 1
TNFSF11 MT-ND1 272 0 0 429 1 1
TNFSF11 WNT3A 0 0 508 519 1 2
TNFSF11 MAP2K6 0 0 292 293 1 1
TNFSF11 ATG5 0 0 171 171 1 2
TNFSF11 LGR5 0 0 203 204 1 1
TNFSF11 ITGB3 0 0 548 548 1 1
TNFSF11 BMP8A 0 0 56 160 1 1
TNFSF11 TLR8 0 0 187 204 1 1
TNFSF11 XBP1 0 0 155 154 1 2
TNFSF11 CXCR3 0 0 324 338 1 1
TNFSF11 STAT2 0 0 106 213 1 1
TNFSF11 SOX6 0 0 207 207 1 1
TNFSF11 IRF1 0 0 150 172 1 2
TNFSF11 ATP4A 0 0 417 416 1 1
TNFSF11 TNFAIP2 0 0 181 190 1 1
TNFSF11 ELN 0 0 296 296 1 1
TNFSF11 CTF1 0 0 229 228 1 1
TNFSF11 CST7 0 0 74 463 1 1
TNFSF11 RGS2 0 0 124 211 1 1
TNFSF11 CTSB 0 0 217 225 1 2
TNFSF11 PRL 0 0 391 390 1 1
TNFSF11 SPI1 0 0 506 520 1 1
TNFSF11 NOX1 0 0 324 338 1 1
TNFSF11 MCL1 0 0 243 242 1 2
TNFSF11 ERVW-1 0 0 175 175 1 1
TNFSF11 DLK1 0 0 139 190 1 1
TNFSF11 SIRT1 0 0 282 282 1 2
TNFSF11 AIRE 0 0 391 396 1 1
TNFSF11 SEZ6L2 0 0 317 317 1 1
TNFSF11 PDCD1 0 0 218 257 1 2
TNFSF11 ITGAM 0 0 530 530 1 1
TNFSF11 SMAD7 0 0 281 281 1 1
TNFSF11 ACKR2 0 0 203 203 1 1
TNFSF11 MAP3K5 0 0 151 150 1 1
TNFSF11 IFNB1 0 0 424 424 1 1
TNFSF11 DUOX2 0 0 161 179 1 1
TNFSF11 HMGB1 0 0 304 304 1 2
TNFSF11 IRF5 0 0 163 163 1 1
TNFSF11 ESR1 0 0 636 636 1 2
TNFSF11 LYN 0 0 240 239 1 1
TNFSF11 CTSK 0 0 900 911 1 2
TNFSF11 WLS 0 0 223 305 1 1
TNFSF11 FLT4 0 0 160 159 1 1
TNFSF11 MAPK11 0 0 194 270 1 1
TNFSF11 FGF23 0 0 653 655 1 1
TNFSF11 CCDC170 0 0 208 213 1 1
TNFSF11 DUSP1 0 0 235 235 1 1
TNFSF11 TLR2 0 0 464 475 1 2
TNFSF11 ZBTB40 0 0 408 408 1 1
TNFSF11 IFITM5 0 0 153 152 1 1
TNFSF11 PTGER3 0 0 242 245 1 1
TNFSF11 CST5 0 0 181 192 1 1
TNFSF11 NELL1 0 0 147 169 1 1
TNFSF11 TRAF3 0 600 470 778 1 2
TNFSF11 MET 0 0 269 269 1 2
TNFSF11 NTN4 0 0 0 190 1 1
TNFSF11 BECN1 0 0 232 231 1 2
TNFSF11 CCL7 0 0 293 309 1 1
TNFSF11 SDC1 0 0 419 418 1 1
TNFSF11 PTGES 0 0 261 274 1 1
TNFSF11 THBS1 0 0 213 221 1 1
TNFSF11 ITGA2 0 0 234 234 1 1
TNFSF11 ANXA1 0 0 141 369 1 1
TNFSF11 TLR6 0 0 212 312 1 1
TNFSF11 IL2 0 0 465 465 1 1
TNFSF11 ARL4C 0 0 357 357 1 1
TNFSF11 SFRP2 0 0 374 374 1 1
TNFSF11 DLX5 0 0 377 389 1 1
TNFSF11 PGF 0 0 171 171 1 1
TNFSF11 MADCAM1 0 0 371 371 1 1
TNFSF11 DNAJB9 271 0 0 271 1 2
TNFSF11 CARD11 0 0 98 152 1 1
TNFSF11 TFG 0 0 150 191 1 1
TNFSF11 NOD1 0 0 218 235 1 2
TNFSF11 FZD5 0 0 128 164 1 1
TNFSF11 IL18R1 0 0 143 235 1 1
TNFSF11 CD86 0 0 392 405 1 1
TNFSF11 ENSG00000277117 0 0 184 183 1 1
TNFSF11 BGN 0 0 265 265 1 1
TNFSF11 STAT5A 0 0 335 349 1 1
TNFSF11 ANGPTL4 0 0 193 202 1 1
TNFSF11 MMP24 0 0 122 277 1 1
TNFSF11 FOXN1 0 0 181 181 1 1
TNFSF11 MSTN 0 0 294 294 1 1
TNFSF11 PTPN11 0 0 190 190 1 1
TNFSF11 TWIST1 0 0 261 261 1 1
TNFSF11 CCL27 0 0 218 218 1 1
TNFSF11 FASLG 0 0 455 209 1 1
TNFSF11 KDM6B 0 0 203 226 1 1
TNFSF11 FOS 0 900 754 975 1 2
TNFSF11 ANXA2R 0 0 180 179 1 1
TNFSF11 SOCS3 0 0 284 284 1 1
TNFSF11 AKAP11 0 0 357 424 1 1
TNFSF11 MATK 0 0 167 182 1 1
TNFSF11 ASB2 0 0 66 166 1 1
TNFSF11 FOXO1 0 0 320 319 1 2
TNFSF11 SIGLEC15 0 0 294 294 1 1
TNFSF11 KRAS 0 0 161 245 1 2
TNFSF11 ITGB2 0 0 144 186 1 1
TNFSF11 IFNGR1 0 0 133 322 1 1
TNFSF11 CCL17 0 0 281 292 1 1
TNFSF11 CD3E 0 0 146 198 1 1
TNFSF11 SOD2 0 0 166 165 1 2
TNFSF11 SLC34A3 0 0 218 219 1 1
TNFSF11 PTH 0 0 864 877 1 1
TNFSF11 TFE3 0 0 181 181 1 2
TNFSF11 VIPR1 0 0 60 183 1 1
TNFSF11 RNF13 0 0 54 420 1 1
TNFSF11 CAMK4 0 0 206 206 1 1
TNFSF11 CCL8 0 0 187 312 1 1
TNFSF11 KDM2B 0 0 278 278 1 1
TNFSF11 BTRC 0 0 144 168 1 1
TNFSF11 WNT2 0 0 260 589 1 1
TNFSF11 IL1RAP 0 0 162 161 1 1
TNFSF11 ATP6V1C1 0 0 173 174 1 1
TNFSF11 DUSP2 0 0 146 175 1 1
TNFSF11 S100A12 0 0 162 161 1 1
TNFSF11 CHUK 0 0 517 525 1 1
TNFSF11 NRROS 0 0 171 171 1 1
TNFSF11 FABP4 0 0 281 281 1 1
TNFSF11 GUSB 0 0 171 171 1 1
TNFSF11 ADM 0 0 181 181 1 2
TNFSF11 PTPN12 0 0 124 153 1 1
TNFSF11 CDKN2A 0 0 636 735 1 2
TNFSF11 MGP 0 0 466 469 1 1
TNFSF11 CXCL16 0 0 214 214 1 1
TNFSF11 ARRB2 0 0 167 167 1 1
TNFSF11 SOCS2 0 0 166 165 1 1
TNFSF11 BMPR1B 0 0 194 225 1 1
TNFSF11 ITGAX 0 0 391 390 1 1
TNFSF11 MRC1 0 0 193 277 1 1
TNFSF11 GSK3B 0 0 217 300 1 2
TNFSF11 ARRB1 0 0 308 307 1 1
TNFSF11 FOLH1 0 0 139 162 1 1
TNFSF11 FGF8 0 0 43 180 1 1
TNFSF11 WNT3 0 0 286 302 1 1
TNFSF11 TRPV5 0 0 391 392 1 1
TNFSF11 AHSG 0 0 340 340 1 1
TNFSF11 FGF11 0 0 0 189 1 1
TNFSF11 LTBR 0 600 519 807 1 1
TNFSF11 CSF1 0 0 928 929 1 1
TNFSF11 RIPK1 0 0 181 181 1 2
TNFSF11 PRDM1 0 0 259 286 1 1
TNFSF11 HDAC1 0 0 183 183 1 2
TNFSF11 NOD2 0 0 263 279 1 2
TNFSF11 CIITA 0 0 150 243 1 1
TNFSF11 TWIST2 0 0 193 193 1 1
TNFSF11 CEBPB 0 0 340 340 1 2
TNFSF11 FGF9 0 0 134 197 1 1
TNFSF11 IL1RL1 0 0 166 213 1 1
TNFSF11 FIGF 0 0 181 181 1 1
TNFSF11 ENPP1 0 0 293 297 1 1
TNFSF11 F3 0 0 183 183 1 1
TNFSF11 CASP3 0 0 470 470 1 2
TNFSF11 SMURF1 0 0 232 231 1 1
TNFSF11 PTGS2 0 0 558 565 1 2
TNFSF11 CCL11 0 0 212 266 1 1
TNFSF11 FGF19 0 0 81 224 1 1
TNFSF11 IL33 0 0 391 390 1 2
TNFSF11 CXCL1 0 0 394 423 1 2
TNFSF11 MMP14 0 0 359 370 1 1
TNFSF11 PLEKHM1 0 0 377 377 1 1
TNFSF11 NLRP3 0 0 293 293 1 2
TNFSF11 REL 0 0 395 394 1 2
TNFSF11 HDAC9 0 0 164 163 1 1
TNFSF11 BRCA2 0 0 154 153 1 1
TNFSF11 CD5 0 0 202 219 1 1
TNFSF11 CD28 0 0 390 403 1 1
TNFSF11 CYBB 0 0 234 251 1 2
TNFSF11 GPR65 0 0 166 214 1 1
TNFSF11 VEGFC 0 0 271 275 1 1
TNFSF11 GDF11 0 0 181 181 1 1
TNFSF11 CXCL5 0 0 330 356 1 1
TNFSF11 IHH 0 0 423 422 1 1
TNFSF11 TNFSF13B 0 600 673 866 1 1
TNFSF11 BCAR1 0 0 203 204 1 1
TNFSF11 ALOX5 0 0 218 218 1 1
TNFSF11 CTSS 0 0 45 271 1 1
TNFSF11 ACE 0 0 293 293 1 1
TNFSF11 NOTCH2 0 0 341 348 1 1
TNFSF11 FGF22 0 0 0 189 1 1
TNFSF11 CD1B 0 0 234 234 1 1
TNFSF11 IL13 0 0 456 456 1 2
TNFSF11 TNFRSF10B 0 0 395 395 1 2
TNFSF11 DLX3 0 0 151 150 1 1
TNFSF11 REN 0 0 262 262 1 1
TNFSF11 STAT5B 0 0 295 310 1 1
TNFSF11 RAB7B 0 0 116 176 1 1
TNFSF11 TGFB1 0 0 327 437 1 2
TNFSF11 MSX2 0 0 474 474 1 1
TNFSF11 CLCN7 0 0 608 608 1 1
TNFSF11 IKZF2 0 0 61 161 1 1
TNFSF11 ASIC3 0 0 175 175 1 1
TNFSF11 CDKN1B 0 0 181 181 1 2
TNFSF11 CD2 0 0 145 160 1 1
TNFSF11 PRKCD 0 0 164 163 1 2
TNFSF11 TRPV4 0 0 246 245 1 1
TNFSF11 CCR4 0 0 134 152 1 1
TNFSF11 MRPS2 0 0 235 235 1 1
TNFSF11 MMP10 0 0 172 260 1 1
TNFSF11 ADIPOR2 0 0 163 163 1 1
TNFSF11 EGFL6 0 0 74 267 1 1
TNFSF11 CLEC5A 0 0 217 217 1 1
TNFSF11 TBK1 0 0 181 181 1 2
TNFSF11 PPBP 0 0 128 158 1 1
TNFSF11 ASPN 0 0 209 209 1 1
TNFSF11 NCR2 0 0 155 173 1 1
TNFSF11 MGST1 0 0 0 408 1 1
TNFSF11 IL32 0 0 233 232 1 1
TNFSF11 FOXP3 0 0 503 503 1 2
TNFSF11 HMOX1 0 0 370 370 1 2
TNFSF11 MMP12 0 0 204 216 1 1
TNFSF11 JAK1 0 0 261 261 1 2
TNFSF11 MITF 0 0 517 517 1 2
TNFSF11 RARRES2 0 0 160 159 1 1
TNFSF11 KDR 0 0 324 323 1 2
TNFSF11 DMP1 0 0 392 485 1 1
TNFSF11 NFATC2 0 0 391 404 1 1
TNFSF11 KLRB1 0 0 135 152 1 1
TNFSF11 SLC13A2 0 0 0 627 1 1
TNFSF11 RAC2 0 0 210 222 1 1
TNFSF11 RGS18 0 0 180 179 1 1
TNFSF11 CD93 0 0 120 171 1 1
TNFSF11 FLT1 0 0 286 286 1 1
TNFSF11 TNFRSF18 0 0 293 351 1 1
TNFSF11 JDP2 0 0 397 396 1 1
TNFSF11 IL19 0 0 242 241 1 1
TNFSF11 TLR3 0 0 270 285 1 2
TNFSF11 SEMA4F 0 0 155 154 1 1
TNFSF11 LGALS3 0 0 206 212 1 2
TNFSF11 MIF 0 0 270 270 1 2
TNFSF11 STAT6 0 0 294 320 1 1
TNFSF11 TNFSF12 0 600 402 750 1 1
TNFSF11 HNF4A 0 0 295 295 1 1
TNFSF11 CCR8 0 0 150 182 1 1
TNFSF11 EIF2AK3 0 0 391 404 1 2
TNFSF11 ALYREF 0 0 166 165 1 1
TNFSF11 MARCKSL1 0 0 150 173 1 1
TNFSF11 APOE 0 0 267 267 1 2
TNFSF11 IL36B 0 0 156 427 1 1
TNFSF11 FOXO3 0 0 261 261 1 2
TNFSF11 FEZF2 0 0 155 154 1 1
TNFSF11 SLC2A4 0 0 141 160 1 1
TNFSF11 IL26 0 0 218 218 1 1
TNFSF11 LIFR 0 0 202 202 1 1
TNFSF11 IL25 0 0 216 216 1 1
TNFSF11 ITGA6 0 0 385 384 1 1
TNFSF11 CD47 0 0 267 328 1 2
TNFSF11 BGLAP 0 0 870 881 1 1
TNFSF11 SMURF2 0 0 170 169 1 1
TNFSF11 RAG1 0 0 181 204 1 1
TNFSF11 CDC42 0 0 260 260 1 2
TNFSF11 F2 0 0 95 151 1 1
TNFSF11 NAA16 0 0 53 305 1 1
TNFSF11 SRC 270 0 774 828 1 2
TNFSF11 DKK1 0 0 731 731 1 1
TNFSF11 ADAM12 0 0 205 205 1 1
TNFSF11 IRF8 0 0 413 417 1 1
TNFSF11 FBN1 0 0 155 241 1 1
TNFSF11 TLR9 0 0 336 350 1 2
TNFSF11 CREM 0 0 64 157 1 1
TNFSF11 GZMK 0 0 46 306 1 1
TNFSF11 CRTAP 0 0 218 218 1 1
TNFSF11 CLCA1 0 0 0 600 1 1
TNFSF11 CD1D 0 0 274 274 1 1
TNFSF11 TNFSF8 0 0 413 425 1 1
TNFSF11 GPRC6A 0 0 244 243 1 1
TNFSF11 MAP3K1 0 0 111 166 1 1
TNFSF11 GOSR1 286 0 0 286 1 1
TNFSF11 CTSC 0 0 137 178 1 1
TNFSF11 SHBG 0 0 241 240 1 1
TNFSF11 VEGFB 0 0 160 159 1 1
TNFSF11 KCTD4 0 0 68 271 1 1
TNFSF11 ERBB2 0 0 394 394 1 2
TNFSF11 TSPAN5 0 0 142 160 1 1
TNFSF11 ARG2 0 0 142 175 1 1
TNFSF11 NGF 0 0 284 284 1 2
TNFSF11 CD34 0 0 391 390 1 2
TNFSF11 CTSO 0 0 0 188 1 1
TNFSF11 IRF3 0 0 184 183 1 2
TNFSF11 CR2 0 0 135 160 1 1
TNFSF11 BCL6 0 0 283 282 1 1
TNFSF11 SOSTDC1 0 0 182 181 1 1
TNFSF11 CHRD 0 0 171 171 1 1
TNFSF11 NFATC4 0 0 194 194 1 1
TNFSF11 DCDC1 0 0 186 186 1 1
TNFSF11 GJA1 0 0 416 416 1 1
TNFSF11 GPT 0 0 170 169 1 1
TNFSF11 BMP8B 0 0 95 195 1 1
TNFSF11 ID2 0 0 324 323 1 1
TNFSF11 IL11 0 0 662 666 1 1
TNFSF11 KRT18 0 0 139 157 1 1
TNFSF11 EIF4EBP1 0 0 433 433 1 2
TNFSF11 CYLD 0 0 447 447 1 1
TNFSF11 CXCL10 0 0 400 400 1 2
TNFSF11 GP2 0 0 339 353 1 1
TNFSF11 FGF3 0 0 54 199 1 1
TNFSF11 AXL 0 0 167 167 1 2
TNFSF11 IKBKB 0 0 469 470 1 2
TNFSF11 COL1A2 0 0 469 469 1 1
TNFSF11 TGIF2 0 0 195 198 1 1
TNFSF11 PANX1 0 0 171 171 1 1
TNFSF11 DUOX1 0 0 180 197 1 1
TNFSF11 FGFR1 0 0 244 243 1 1
TNFSF11 VIP 0 0 180 179 1 1
TNFSF11 ZKSCAN7 0 0 297 297 1 1
TNFSF11 XIAP 0 0 206 206 1 2
TNFSF11 SEMA6D 0 0 193 193 1 1
TNFSF11 RUNX2 0 0 845 861 1 2
TNFSF11 FMOD 0 0 181 181 1 1
TNFSF11 CST3 0 0 410 418 1 1
TNFSF11 NOX4 0 0 210 227 1 2
TNFSF11 LY96 0 0 165 165 1 1
TNFSF11 CSF2 0 0 567 567 1 1
TNFSF11 CD48 0 0 155 162 1 1
TNFSF11 MKI67 0 0 45 179 1 2
TNFSF11 FBN2 0 0 96 188 1 1
TNFSF11 ACKR1 0 0 210 210 1 1
TNFSF11 IL17C 0 0 167 167 1 1
TNFSF11 TGFB2 0 0 326 356 1 1
TNFSF11 AKT1 213 0 637 706 1 2
TNFSF11 SPIB 0 0 409 423 1 1
TNFSF11 PPARG 0 0 518 521 1 2
TNFSF11 RAMP3 0 0 108 351 1 1
TNFSF11 IL17RB 0 0 195 195 1 1
TNFSF11 ATF4 0 0 378 379 1 2
TNFSF11 INPP5D 0 0 157 204 1 1
TNFSF11 CD4 0 0 633 649 1 2
TNFSF11 VCAM1 0 0 470 485 1 1
TNFSF11 SEMA7A 0 0 182 181 1 1
TNFSF11 RSPO3 0 0 169 220 1 1
TNFSF11 PTHLH 0 0 764 787 1 1
TNFSF11 MEPE 0 0 561 561 1 1
TNFSF11 FAS 0 0 213 229 1 2
TNFSF11 GPR4 0 0 140 166 1 1
TNFSF11 GH1 0 0 151 150 1 1
TNFSF11 MMP7 213 0 330 516 1 1
TNFSF11 VCL 0 0 266 266 1 1
TNFSF11 IL23R 0 0 264 264 1 1
TNFSF11 NFAT5 0 0 430 453 1 1
TNFSF11 ACVR2A 0 0 180 186 1 1
TNFSF11 SEMA4D 0 0 337 352 1 1
TNFSF11 SRR 0 0 95 179 1 1
TNFSF11 TNF 0 600 923 746 1 2
TNFSF11 TECPR2 0 0 0 223 1 2
TNFSF11 NOV 0 0 144 167 1 1
TNFSF11 WISP1 0 0 254 254 1 1
TNFSF11 VDR 0 0 566 566 1 2
TNFSF11 MMP3 213 0 562 659 1 1
TNFSF11 TSHR 0 0 142 160 1 1
TNFSF11 DKK3 0 0 154 153 1 1
TNFSF11 IL1RN 0 0 325 325 1 1
TNFSF11 ADAMTS4 0 0 310 309 1 1
TNFSF11 GGPS1 0 0 268 268 1 1
TNFSF11 NT5E 0 0 265 265 1 1
TNFSF11 KRT14 0 0 140 159 1 1
TNFSF11 ITK 0 0 92 150 1 1
TNFSF11 IL7 0 0 613 622 1 1
TNFSF11 BDNF 0 0 181 181 1 2
TNFSF11 MEF2C 0 0 240 239 1 1
TNFSF11 CD44 0 0 459 459 1 2
TNFSF11 MMP25 0 0 125 259 1 1
TNFSF11 RETN 0 0 261 261 1 1
TNFSF11 SLC4A2 0 0 150 168 1 1
TNFSF11 ROR2 0 0 211 211 1 1
TNFSF11 ATF3 0 0 150 168 1 2
TNFSF11 FAM216B 0 0 81 339 1 1
TNFSF11 EPHB4 0 0 423 422 1 1
TNFSF11 CNR1 0 0 306 306 1 1
TNFSF11 THBS2 0 0 144 152 1 1
TNFSF11 BTK 0 0 341 341 1 1
TNFSF11 SOCS1 0 0 269 285 1 1
TNFSF11 SPESP1 0 0 167 167 1 1
TNFSF11 UBE2Z 0 0 0 207 1 1
TNFSF11 ITIH4 0 0 202 202 1 1
TNFSF11 IGF1 0 0 638 644 1 2
TNFSF11 IRF7 0 0 181 181 1 1
TNFSF11 MAPK1 213 0 215 355 1 2
TNFSF11 MMP27 0 0 0 351 1 1
TNFSF11 CSF1R 0 0 976 977 1 1
TNFSF11 WDFY3 0 0 92 154 1 2
TNFSF11 IL34 0 0 798 800 1 1
TNFSF11 NFKB2 0 0 469 480 1 1
TNFSF11 GCG 0 0 218 218 1 1
TNFSF11 PTCH1 0 0 163 169 1 1
TNFSF11 TNFAIP3 0 0 227 226 1 2
TNFSF11 ATP12A 0 0 414 414 1 1
TNFSF11 AXIN2 0 0 308 307 1 1
TNFSF11 SPN 0 0 141 178 1 1
TNFSF11 SOX5 0 0 155 154 1 1
TNFSF11 PPP6R3 0 0 138 191 1 1
TNFSF11 CD70 0 0 295 295 1 1
TNFSF11 MAP3K14 0 600 213 675 1 1
TNFSF11 IL1R2 0 0 181 248 1 1
TNFSF11 IL5 0 0 337 337 1 1
TNFSF11 VWF 0 0 249 248 1 1
TNFSF11 CD63 0 0 157 156 1 2
TNFSF11 TNFAIP6 417 0 257 578 1 1
TNFSF11 IFNAR1 0 0 171 263 1 1
TNFSF11 ENSG00000272980 0 0 401 422 1 1
TNFSF11 TFRC 0 0 162 161 1 1
TNFSF11 CPED1 0 0 290 318 1 1
TNFSF11 MMP8 0 0 421 439 1 1
TNFSF11 BCL2A1 0 0 152 151 1 1
TNFSF11 GPNMB 0 0 243 242 1 1
TNFSF11 PRLR 0 0 260 264 1 1
TNFSF11 SFRP4 0 0 374 374 1 1
TNFSF11 TNFSF14 0 600 393 751 1 1
TNFSF11 TXNIP 0 0 297 297 1 2
TNFSF11 CXCL3 0 0 142 183 1 1
TNFSF11 RAB7A 0 0 112 173 1 2
TNFSF11 CD9 0 0 270 270 1 1
TNFSF11 RSPO1 0 0 257 256 1 1
TNFSF11 FGF2 0 0 469 470 1 2
TNFSF11 RELB 0 0 519 530 1 2
TNFSF11 THNSL2 0 0 495 495 1 1
TNFSF11 WNT9A 0 0 282 282 1 1
TNFSF11 CD19 0 0 363 384 1 1
TNFSF11 WNT8B 0 0 261 261 1 1
TNFSF11 GREB1 0 0 122 162 1 1
TNFSF11 DVL2 0 0 134 170 1 2
TNFSF11 BLNK 0 0 330 330 1 1
TNFSF11 IRAK2 0 0 120 211 1 1
TNFSF11 ANXA2 0 0 284 284 1 1
TNFSF11 NOS3 0 0 263 263 1 2
TNFSF11 VPS37B 0 0 61 160 1 1
TNFSF11 HDAC7 0 0 150 172 1 1
TNFSF11 EPHA1 0 0 231 230 1 1
TNFSF11 JUND 0 0 208 208 1 1
TNFSF11 SEMA3A 0 0 321 321 1 1
TNFSF11 FSHR 0 0 160 159 1 1
TNFSF11 CD274 0 0 289 288 1 2
TNFSF11 TNFRSF10D 0 0 260 260 1 1
TNFSF11 CCND1 0 0 426 430 1 2
TNFSF11 NCOR1 0 0 116 252 1 1
TNFSF11 PGR 0 0 427 431 1 1
TNFSF11 LEPREL2 0 0 148 167 1 1
TNFSF11 AHR 0 0 231 230 1 2
TNFSF11 SERPINE1 0 0 208 208 1 1
TNFSF11 RPS6KB1 0 0 195 195 1 2
TNFSF11 TNFAIP8 0 0 60 154 1 1
TNFSF11 REM1 0 0 0 189 1 1
TNFSF11 FCGR1A 0 0 372 372 1 1
TNFSF11 AGTR1 0 0 166 165 1 1
TNFSF11 HEY1 0 0 260 260 1 1
TNFSF11 ADRB2 0 0 369 369 1 1
TNFSF11 IRS1 0 0 180 179 1 2
TNFSF11 CBL 0 0 334 348 1 1
TNFSF11 SAG 0 0 180 179 1 1
TNFSF11 EGR2 0 0 166 165 1 1
TNFSF11 METTL21C 0 0 142 164 1 1
TNFSF11 LOX 0 0 358 372 1 2
TNFSF11 NTRK1 0 0 260 260 1 1
TNFSF11 CD207 0 0 389 388 1 1
TNFSF11 CYP24A1 0 0 391 403 1 1
TNFSF11 BMP5 0 0 181 181 1 1
TNFSF11 HGF 0 0 391 390 1 2
TNFSF11 SFTPD 0 0 400 400 1 1
TNFSF11 ENSG00000264813 0 0 261 261 1 1
TNFSF11 LRP6 0 0 468 480 1 1
TNFSF11 POU5F1 0 0 141 156 1 2
TNFSF11 DNAJB7 0 0 181 181 1 1
TNFSF11 ADAMTS3 0 0 291 290 1 1
TNFSF11 LCP1 0 0 138 271 1 1
TNFSF11 BMPR2 0 0 233 234 1 1
TNFSF11 RUNX1 0 0 61 155 1 2
TNFSF11 CCL1 0 0 171 171 1 1
TNFSF11 CAT 0 0 298 298 1 2
TNFSF11 PECAM1 0 0 391 390 1 1
TNFSF11 WNT10B 0 0 503 516 1 1
TNFSF11 PTK2B 0 0 390 403 1 1
TNFSF11 XPR1 0 0 150 271 1 1
TNFSF11 CTLA4 0 0 493 504 1 2
TNFSF11 EFNA1 0 0 92 227 1 1
TNFSF11 CHIT1 0 0 146 165 1 1
TNFSF11 GNB2L1 0 0 90 172 1 1
TNFSF11 TRPS1 0 0 66 418 1 1
TNFSF11 CCL19 0 0 394 407 1 1
TNFSF11 LDLR 0 0 266 266 1 2
TNFSF11 OCSTAMP 0 0 668 683 1 1
TNFSF11 ALPL 0 0 557 564 1 1
TNFSF11 SCX 0 0 63 225 1 1
TNFSF11 CD38 0 0 267 267 1 2
TNFSF11 AGBL2 0 0 209 209 1 1
TNFSF11 SMAD6 0 0 213 213 1 1
TNFSF11 MDK 0 0 96 159 1 1
TNFSF11 HPRT1 0 0 370 370 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0005125 Molecular Function cytokine activity enables IDA
GO:0005125 Molecular Function cytokine activity enables NAS
GO:0042802 Molecular Function identical protein binding enables IEA
GO:0005515 Molecular Function protein binding enables IPI
GO:0005164 Molecular Function tumor necrosis factor receptor binding enables NAS
GO:0032813 Molecular Function tumor necrosis factor receptor superfamily binding enables IC
GO:0070371 Biological Process ERK1 and ERK2 cascade involved_in IEA
GO:0007254 Biological Process JNK cascade involved_in IEA
GO:0071847 Biological Process TNFSF11-mediated signaling pathway involved_in IDA
GO:0045453 Biological Process bone resorption involved_in IEA
GO:0055074 Biological Process calcium ion homeostasis involved_in IEA
GO:0019722 Biological Process calcium-mediated signaling involved_in ISS
GO:0007249 Biological Process canonical NF-kappaB signal transduction involved_in IEA
GO:1990830 Biological Process cellular response to leukemia inhibitory factor involved_in IEA
GO:0019221 Biological Process cytokine-mediated signaling pathway involved_in IDA
GO:0006955 Biological Process immune response involved_in NAS
GO:0060749 Biological Process mammary gland alveolus development involved_in IEA
GO:0033598 Biological Process mammary gland epithelial cell proliferation involved_in IEA
GO:0002548 Biological Process monocyte chemotaxis involved_in IDA
GO:0000122 Biological Process negative regulation of transcription by RNA polymerase II involved_in IEA
GO:0001503 Biological Process ossification involved_in IEA
GO:0036035 Biological Process osteoclast development involved_in IEA
GO:0030316 Biological Process osteoclast differentiation involved_in IDA
GO:0030316 Biological Process osteoclast differentiation involved_in ISS
GO:0030316 Biological Process osteoclast differentiation involved_in NAS
GO:0002158 Biological Process osteoclast proliferation involved_in IEA
GO:0038001 Biological Process paracrine signaling involved_in IEA
GO:0043491 Biological Process phosphatidylinositol 3-kinase/protein kinase B signal transduction involved_in IEA
GO:0051091 Biological Process positive regulation of DNA-binding transcription factor activity involved_in ISS
GO:0071848 Biological Process positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling involved_in IDA
GO:0046330 Biological Process positive regulation of JNK cascade involved_in IEA
GO:0043406 Biological Process positive regulation of MAP kinase activity involved_in IDA
GO:0051092 Biological Process positive regulation of NF-kappaB transcription factor activity involved_in IDA
GO:0050870 Biological Process positive regulation of T cell activation involved_in IDA
GO:0045780 Biological Process positive regulation of bone resorption involved_in IDA
GO:0043123 Biological Process positive regulation of canonical NF-kappaB signal transduction involved_in IEA
GO:0051466 Biological Process positive regulation of corticotropin-releasing hormone secretion involved_in ISS
GO:0071812 Biological Process positive regulation of fever generation by positive regulation of prostaglandin secretion involved_in ISS
GO:0010628 Biological Process positive regulation of gene expression involved_in IEA
GO:0034112 Biological Process positive regulation of homotypic cell-cell adhesion involved_in IDA
GO:1902533 Biological Process positive regulation of intracellular signal transduction involved_in IDA
GO:2001206 Biological Process positive regulation of osteoclast development involved_in IEA
GO:0045672 Biological Process positive regulation of osteoclast differentiation involved_in IDA
GO:0051897 Biological Process positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction involved_in IEA
GO:0045944 Biological Process positive regulation of transcription by RNA polymerase II involved_in IDA
GO:0044691 Biological Process tooth eruption involved_in IEA
GO:0033209 Biological Process tumor necrosis factor-mediated signaling pathway involved_in ISS
GO:0005737 Cellular Component cytoplasm located_in IEA
GO:0005576 Cellular Component extracellular region located_in NAS
GO:0005576 Cellular Component extracellular region located_in TAS
GO:0005615 Cellular Component extracellular space located_in IEA
GO:0005886 Cellular Component plasma membrane located_in NAS
GO:0005886 Cellular Component plasma membrane located_in TAS
Pathways
Name DB ID
Cytokine Signaling in Immune system Reactome R-HSA-1280215
Immune System Reactome R-HSA-168256
TNFR2 non-canonical NF-kB pathway Reactome R-HSA-5668541
TNFs bind their physiological receptors Reactome R-HSA-5669034
TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway Reactome R-HSA-5676594
Type I collagen synthesis in the context of osteogenesis imperfecta (WP4786) WikiPathways WP4786_r117852
Breast cancer pathway (WP4262) WikiPathways WP4262_r123349
Autosomal recessive osteopetrosis pathways (WP4788) WikiPathways WP4788_r117658
Osteoclast signaling (WP12) WikiPathways WP12_r116896
Clock-controlled autophagy in bone metabolism (WP5205) WikiPathways WP5205_r122560
Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4) (WP2817) WikiPathways WP2817_r123894
IL-18 signaling pathway (WP4754) WikiPathways WP4754_r115147
Pluripotent stem cell differentiation pathway (WP2848) WikiPathways WP2848_r120814
Osteoblast signaling (WP322) WikiPathways WP322_r117584
Vitamin D receptor pathway (WP2877) WikiPathways WP2877_r119905
Regucalcin in proximal tubule epithelial kidney cells (WP4838) WikiPathways WP4838_r110282
RANKL/RANK signaling pathway (WP2018) WikiPathways WP2018_r120672
Transcripts
Accession Version MolecularType Name NCBI Comments
NM_033012 4 mRNA transcript variant 2 NC_000013 Reference
XM_047430707 1 mRNA transcript variant X2 NC_000013 Reference
NM_003701 4 mRNA transcript variant 1 NC_000013 Reference
XM_011535280 3 mRNA transcript variant X3 NC_000013 Reference
XM_017020803 3 mRNA transcript variant X4 NC_000013 Reference
XM_017020802 2 mRNA transcript variant X1 NC_000013 Reference