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RUNX1

RUNX family transcription factor 1
General Information
Name RUNX family transcription factor 1
Alias
  • runt-related transcription factor 1
  • AML1-ETO fusion
  • AML1-ETO fusion protein
  • AML1-EVI-1 fusion protein
  • PEA2-alpha B
  • PEBP2-alpha B
  • SL3-3 enhancer factor 1 alpha B subunit
  • SL3/AKV core-binding factor alpha B subunit
  • acute myeloid leukemia 1 protein
  • core-binding factor, runt domain, alpha subunit 2
  • mutant RUNX1
  • oncogene AML-1
  • polyomavirus enhancer-binding protein 2 alpha B subunit
  • runt related transcription factor 1
Gene_family Runt-related transcription factors
organism Homo sapiens
entrez_id 861
location 21q22.12
transcript_count 18
exon_count 12
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
    Stringdb Runt-related transcription factor 1; CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL-3 and GM-CSF promoters. The alpha subunit binds DNA and appears to have a role in the development of normal hematopoiesis. Isoform AML-1L interferes with the transactivation activity of RUNX1. Acts synergistically with ELF4 to transactivate the IL-3 promoter and with ELF2 to transactivate the mouse BLK promoter. Inhibits KAT6B- dependent transcriptional activation. Controls the [...]
    nextProt Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'-TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. The heterodimers bind to the core site of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL3 and GM-CSF promoters (Probable). Essential for the development of normal hematopoiesis (PubMed:17431401). Acts synergistically with ELF4 to transactivate the IL-3 promoter and with ELF2 to transactivate the BLK promoter (PubMed:10207087, PubMed:14970218). Inhibits KAT6B-dependent transcriptional activation (By similarity). Involved in lineage commitment of immature T cell precursors. CBF complexes repress ZBTB7B transcription factor during cytotoxic (CD8+) T cell development. They bind to RUNX-binding sequence within the ZBTB7B locus acting as transcriptional silencer and allowing for cytotoxic T cell differentiation. CBF complexes binding to the transcriptional silencer is essential for recruitment of nuclear protein complexes that catalyze epigenetic modifications to establish epigenetic ZBTB7B silencing (By similarity). Controls the anergy and suppressive function of regulatory T-cells (Treg) by associating with FOXP3. Activates the expression of IL2 and IFNG and down-regulates the expression of TNFRSF18, IL2RA and CTLA4, in conventional T-cells (PubMed:17377532). Positively regulates the expression of RORC in T-helper 17 cells (By similarity).
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
RUNX1 BioGRID TLE3 GeneID BioGRID Affinity Capture-Western; Proximity Label-MS
RUNX1 BioGRID CBFB GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-crystal Structure; Co-purification; Reconstituted Complex; Two-hybrid
RUNX1 BioGRID FOXC1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
RUNX1 BioGRID YTHDC1 GeneID BioGRID Affinity Capture-RNA
RUNX1 BioGRID NAAA GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID FOXF2 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID GPR55 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID FBXW12 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID RUNX2 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID BTF3 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID ATG7 GeneID BioGRID Phenotypic Enhancement
RUNX1 BioGRID GSK3A GeneID BioGRID Two-hybrid
RUNX1 BioGRID CIC GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID HGS GeneID BioGRID Two-hybrid
RUNX1 BioGRID CCNK GeneID BioGRID Affinity Capture-MS; Two-hybrid
RUNX1 BioGRID TEAD2 GeneID BioGRID Two-hybrid
RUNX1 BioGRID TEAD4 GeneID BioGRID Two-hybrid
RUNX1 BioGRID SNRPC GeneID BioGRID Two-hybrid
RUNX1 BioGRID GCC1 GeneID BioGRID Two-hybrid
RUNX1 BioGRID FAM222B GeneID BioGRID Two-hybrid
RUNX1 BioGRID VPS37C GeneID BioGRID Two-hybrid
RUNX1 BioGRID BAG3 GeneID BioGRID Two-hybrid
RUNX1 BioGRID BAG4 GeneID BioGRID Two-hybrid
RUNX1 BioGRID OLIG3 GeneID BioGRID Two-hybrid
RUNX1 BioGRID TEKT5 GeneID BioGRID Two-hybrid
RUNX1 BioGRID FBXO17 GeneID BioGRID Two-hybrid
RUNX1 BioGRID NFKBID GeneID BioGRID Two-hybrid
RUNX1 BioGRID MAPK1 GeneID BioGRID Biochemical Activity
RUNX1 BioGRID ORF3b GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
RUNX1 BioGRID CTBP2 GeneID BioGRID Affinity Capture-MS; Two-hybrid
RUNX1 BioGRID H4C1 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID Hipk2 GeneID BioGRID Affinity Capture-Western
RUNX1 BioGRID VIRMA GeneID BioGRID Affinity Capture-RNA
RUNX1 BioGRID MAD2L2 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID IKZF3 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
RUNX1 BioGRID IKZF1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
RUNX1 BioGRID MYC GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID DCPS GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID RANGAP1 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID MED1 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID ORC2 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID NONO GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID HNRNPM GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID MLLT1 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID MEN1 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID ZNF326 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID LRWD1 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID DHX36 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID KIF2B GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID FERMT3 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID FIP1L1 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID WDCP GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID WDR76 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID LMNB1 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID LMNA GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID LCP1 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID HSPA9 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID HSPA8 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID HSPA5 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID HSPA2 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID HSPA1A GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID HNRNPU GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID HNRNPH1 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID XRCC6 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID FUS GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID EWSR1 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID EIF4A2 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID EEF1A2 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID EEF1A1 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID ARID3A GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID DPYSL2 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID DNMT1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-localization; Two-hybrid
RUNX1 BioGRID DMBT1 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID DHX15 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID DHX9 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID DDX5 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID DDX3X GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID DDX1 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID CTPS1 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID CSTF2 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID CLTC GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID CBFA2T3 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
RUNX1 BioGRID ACTL6A GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID ACTB GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID NUP85 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID RPAP2 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID BRD9 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID GATAD2B GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID RAD18 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID INTS9 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID LRRC40 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID CDKN2AIP GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID PSPC1 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID INTS10 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID GATAD2A GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID DNAJB11 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID CPSF3 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID LARP7 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID SNX9 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID DDX41 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID PABPC1 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID NELFB GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID SF3B3 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID U2SURP GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID CSTF2T GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID HIC2 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID PAXIP1 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID XRN2 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID PSIP1 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID FAF1 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID CPSF6 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID SF3B2 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID USP39 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID IGF2BP1 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID NOP56 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID DDX17 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID SYNCRIP GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID EMG1 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID RBM14 GeneID BioGRID Affinity Capture-MS; Reconstituted Complex
RUNX1 BioGRID PRMT5 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID NDC80 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID TUBA1B GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID HNRNPR GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID TRAP1 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID MED16 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID MED12 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID RBM39 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID MED26 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID MED17 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID MTA2 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID DDX21 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID DNAJA3 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID ASH2L GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID CDC16 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID FUBP1 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID GMPS GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID PABPC4 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID EIF3G GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID EIF3A GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID DYNLL1 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID KHSRP GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID ARID1A GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID TAF15 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID TRIM25 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID SF1 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID EZR GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID UBP1 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID TUBB2A GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID TKT GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID TFRC GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID TCF3 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
RUNX1 BioGRID SRP68 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID SNRPD1 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID SNRNP70 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID SMARCD1 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID SMARCC2 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID SMARCC1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
RUNX1 BioGRID SMARCA4 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
RUNX1 BioGRID SFPQ GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID RPA1 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID DPF2 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
RUNX1 BioGRID RBBP5 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID RARS1 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID HIF1A GeneID BioGRID Affinity Capture-Western; FRET
RUNX1 BioGRID NKX2-1 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID RNF38 GeneID BioGRID Reconstituted Complex
RUNX1 BioGRID UHRF2 GeneID BioGRID Reconstituted Complex
RUNX1 BioGRID DTX2 GeneID BioGRID Reconstituted Complex
RUNX1 BioGRID TRIM5 GeneID BioGRID Reconstituted Complex
RUNX1 BioGRID RNF44 GeneID BioGRID Reconstituted Complex
RUNX1 BioGRID WWP1 GeneID BioGRID Reconstituted Complex
RUNX1 BioGRID STUB1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
RUNX1 BioGRID DZIP3 GeneID BioGRID Reconstituted Complex
RUNX1 BioGRID NEDD4 GeneID BioGRID Reconstituted Complex
RUNX1 BioGRID CTNNB1 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID FANCD2 GeneID BioGRID Affinity Capture-Western
RUNX1 BioGRID Cbfb GeneID BioGRID Affinity Capture-Western
RUNX1 BioGRID CDK9 GeneID BioGRID Negative Genetic
RUNX1 BioGRID BRCA1 GeneID BioGRID Negative Genetic
RUNX1 BioGRID ZNF131 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID KLF6 GeneID BioGRID Affinity Capture-Western
RUNX1 BioGRID NFATC2 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
RUNX1 BioGRID NFATC1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
RUNX1 BioGRID vif GeneID BioGRID Reconstituted Complex
RUNX1 BioGRID HDAC3 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
RUNX1 BioGRID HDAC1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
RUNX1 BioGRID CDK6 GeneID BioGRID Co-localization
RUNX1 BioGRID Cep72 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID SPI1 GeneID BioGRID Reconstituted Complex
RUNX1 BioGRID ELF1 GeneID BioGRID Reconstituted Complex
RUNX1 BioGRID YAP1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
RUNX1 BioGRID RAG1 GeneID BioGRID Affinity Capture-Western
RUNX1 BioGRID EP300 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
RUNX1 BioGRID HDAC11 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID SOX2 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID SMAD3 GeneID BioGRID Affinity Capture-Western
RUNX1 BioGRID CTBP1 GeneID BioGRID Affinity Capture-Western
RUNX1 BioGRID RUNX1 GeneID BioGRID Affinity Capture-Western
RUNX1 BioGRID FOXP3 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
RUNX1 BioGRID NCOR2 GeneID BioGRID Co-crystal Structure
RUNX1 BioGRID NOTCH1 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID UXT GeneID BioGRID Affinity Capture-Western; Reconstituted Complex; Two-hybrid
RUNX1 BioGRID KAT6A GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity
RUNX1 BioGRID PML GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Co-localization
RUNX1 BioGRID CREBBP GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID PRMT1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Biochemical Activity
RUNX1 BioGRID HLA-DMA GeneID BioGRID Affinity Capture-Western
RUNX1 BioGRID HDAC2 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
RUNX1 BioGRID RUNX1T1 GeneID BioGRID Affinity Capture-MS; Co-purification
RUNX1 BioGRID CBFA2T2 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
RUNX1 BioGRID ELAVL1 GeneID BioGRID Affinity Capture-RNA
RUNX1 BioGRID SPEN GeneID BioGRID Protein-peptide
RUNX1 BioGRID KMT2A GeneID BioGRID Affinity Capture-Western
RUNX1 BioGRID COPRS GeneID BioGRID Reconstituted Complex
RUNX1 BioGRID TAL1 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID CDK1 GeneID BioGRID Biochemical Activity
RUNX1 BioGRID SMARCB1 GeneID BioGRID Affinity Capture-Western
RUNX1 BioGRID Vdr GeneID BioGRID Affinity Capture-Western
RUNX1 BioGRID TRIM33 GeneID BioGRID Affinity Capture-MS
RUNX1 BioGRID NR4A2 GeneID BioGRID Affinity Capture-Western
RUNX1 BioGRID SIN3A GeneID BioGRID Affinity Capture-Western
RUNX1 BioGRID NCOR1 GeneID BioGRID Reconstituted Complex
RUNX1 BioGRID UBE2L6 GeneID BioGRID Reconstituted Complex
RUNX1 BioGRID SIAH1 GeneID BioGRID Affinity Capture-Western
RUNX1 BioGRID RARA GeneID BioGRID Affinity Capture-Western
RUNX1 BioGRID tat GeneID BioGRID Reconstituted Complex
RUNX1 BioGRID TCF12 GeneID BioGRID Affinity Capture-Western
RUNX1 BioGRID SUV39H1 GeneID BioGRID Affinity Capture-Western; Co-purification; Reconstituted Complex
RUNX1 BioGRID HIPK2 GeneID BioGRID Affinity Capture-Western; Biochemical Activity
RUNX1 BioGRID MYOD1 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
RUNX1 Protein ELF2 GeneID HPRD
RUNX1 Protein WWTR1 GeneID HPRD
RUNX1 Protein YAP1 GeneID HPRD
RUNX1 Protein KAT6B GeneID HPRD
RUNX1 Protein ELF4 GeneID HPRD
RUNX1 Protein HIPK1 GeneID HPRD
RUNX1 Protein HIPK2 GeneID HPRD
RUNX1 Protein CBFA2T3 GeneID HPRD
RUNX1 Protein CBFA2T2 GeneID HPRD
RUNX1 Protein CDK6 GeneID HPRD
RUNX1 Protein EP300 GeneID HPRD
RUNX1 Protein KAT6A GeneID HPRD
RUNX1 Protein TLE2 GeneID HPRD
RUNX1 Protein NCOR2 GeneID HPRD
RUNX1 Protein TLE1 GeneID HPRD
RUNX1 Protein AR GeneID HPRD
RUNX1 Protein TAFAZZIN GeneID HPRD
RUNX1 Protein FOXP3 GeneID HPRD
RUNX1 Protein SUV39H1 GeneID HPRD
RUNX1 Protein CEBPB GeneID HPRD
RUNX1 Protein CCND1 GeneID HPRD
RUNX1 Protein PAX5 GeneID HPRD
RUNX1 Protein JUN GeneID HPRD
RUNX1 Protein FOS GeneID HPRD
RUNX1 Protein CCND3 GeneID HPRD
RUNX1 Protein CCND2 GeneID HPRD
RUNX1 Protein CBFB GeneID HPRD
RUNX1 Protein CEBPA GeneID HPRD
RUNX1 BioGRID TRAF6 GeneID BioGRID Affinity Capture-Western
RUNX1 BioGRID FHL2 GeneID BioGRID Affinity Capture-Western
RUNX1 BioGRID TLE1 GeneID BioGRID Far Western; Two-hybrid
RUNX1 BioGRID JUN GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
RUNX1 BioGRID FOS GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
RUNX1 BioGRID ELF4 GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
RUNX1 BioGRID ELF2 GeneID BioGRID Reconstituted Complex
RUNX1 BioGRID CEBPB GeneID BioGRID Reconstituted Complex
RUNX1 BioGRID VDR GeneID BioGRID Affinity Capture-Western; Reconstituted Complex
RUNX1 BioGRID SMAD5 GeneID BioGRID Affinity Capture-Western
RUNX1 BioGRID SMAD2 GeneID BioGRID Affinity Capture-Western
RUNX1 BioGRID SMAD1 GeneID BioGRID Affinity Capture-Western
RUNX1 BioGRID PAX5 GeneID BioGRID Reconstituted Complex
RUNX1 BioGRID TLE5 GeneID BioGRID Two-hybrid
RUNX1 BioGRID KAT6B GeneID BioGRID Affinity Capture-Western
RUNX1 Protein TLE1 GeneID BIND AML1a interacts with TLE1.
RUNX1 Protein TLE1 GeneID BIND AML1b interacts with TLE1.
RUNX1 Protein CBFB GeneID BIND Cbf-beta interacts with AML1b. This interaction was modeled on a demonstrated interaction between mouse Cbf-beta and human AML1b.
RUNX1 Protein CBFB GeneID BIND Cbf-beta interacts with AML1a. This interaction was modeled on a demonstrated interaction between mouse Cbf-beta and human AML1a.
StringDB
A B experiments database textmining combined score hadb nhadb
RUNX1 RREB1 0 0 0 154 1 1
RUNX1 RBL1 0 0 0 159 1 1
RUNX1 PRPH 0 0 0 154 1 1
RUNX1 FPGS 0 0 0 303 1 1
RUNX1 TLX1 0 0 261 261 1 1
RUNX1 NCOR2 676 0 402 805 1 1
RUNX1 CSF3 0 0 187 198 1 1
RUNX1 TNFRSF11B 0 0 57 261 1 1
RUNX1 LCP2 0 0 0 195 1 1
RUNX1 HDAC2 486 800 50 912 1 1
RUNX1 SATB2 0 0 0 173 1 1
RUNX1 NR1H2 0 0 0 151 1 1
RUNX1 TRIM24 0 0 435 443 1 1
RUNX1 DHH 0 0 0 189 1 1
RUNX1 MDM2 0 0 150 172 1 2
RUNX1 TP53 0 0 301 422 1 2
RUNX1 CDK4 0 0 108 200 1 2
RUNX1 SMIM3 0 0 155 154 1 1
RUNX1 TFAP4 0 0 0 298 1 1
RUNX1 HOXB4 0 0 241 338 1 1
RUNX1 HOXD13 0 0 158 157 1 1
RUNX1 SOX4 0 0 193 193 1 1
RUNX1 NR2F1 0 0 0 205 1 1
RUNX1 UBR5 0 0 0 202 1 1
RUNX1 GATA3 0 600 236 777 1 1
RUNX1 PPP1R11 0 0 0 461 1 1
RUNX1 STAT3 0 0 96 251 1 2
RUNX1 DEAF1 0 0 146 235 1 1
RUNX1 EZH2 76 0 286 316 1 2
RUNX1 AGO2 0 900 48 900 1 2
RUNX1 PTN 0 0 0 203 1 1
RUNX1 AFF1 0 0 348 373 1 1
RUNX1 HMCN1 0 0 0 208 1 1
RUNX1 KDM7A 0 0 0 642 1 1
RUNX1 JAK2 0 0 283 296 1 2
RUNX1 COL2A1 0 0 0 252 1 2
RUNX1 MDS2 0 0 320 319 1 1
RUNX1 PPARD 0 0 0 151 1 1
RUNX1 BAZ2A 0 0 144 157 1 1
RUNX1 FGR 0 0 0 175 1 1
RUNX1 CTBP2 301 800 0 877 1 1
RUNX1 BRD4 0 0 144 210 1 2
RUNX1 MYBL1 0 0 134 369 1 1
RUNX1 EVX1 0 0 0 339 1 1
RUNX1 DZIP3 270 0 0 270 1 1
RUNX1 PPP1R3C 0 0 0 205 1 1
RUNX1 YTHDF2 0 0 440 440 1 1
RUNX1 MEN1 0 0 82 206 1 1
RUNX1 MX1 0 0 125 168 1 1
RUNX1 DBF4B 0 0 181 181 1 1
RUNX1 IL2RA 0 900 0 924 1 1
RUNX1 NR4A3 0 900 0 903 1 1
RUNX1 SETD4 0 0 0 642 1 1
RUNX1 DCHS1 0 0 0 212 1 1
RUNX1 NR2F6 0 0 67 174 1 1
RUNX1 CBX4 0 600 0 600 1 1
RUNX1 WWTR1 297 0 112 472 1 1
RUNX1 SBNO2 0 0 0 309 1 1
RUNX1 NR1I3 0 0 0 170 1 1
RUNX1 RARG 0 0 0 151 1 1
RUNX1 CCNH 0 900 0 902 1 1
RUNX1 NR0B2 0 0 0 151 1 1
RUNX1 CKMT1B 0 0 211 211 1 1
RUNX1 HIPK1 213 0 0 219 1 1
RUNX1 MYC 122 0 269 390 1 2
RUNX1 HIST1H2BD 0 600 0 600 1 1
RUNX1 RIT1 0 0 0 161 1 1
RUNX1 TRIM33 270 0 61 311 1 1
RUNX1 HOXA9 0 0 454 463 1 1
RUNX1 NR2C1 0 0 0 190 1 1
RUNX1 MBD2 0 0 0 158 1 1
RUNX1 CTSV 0 650 0 650 1 1
RUNX1 ZNF423 0 0 0 180 1 1
RUNX1 PCGF5 0 600 0 658 1 1
RUNX1 MS4A3 0 0 150 171 1 1
RUNX1 CDC5L 0 0 0 303 1 1
RUNX1 MECP2 0 0 81 155 1 1
RUNX1 MYL9 0 900 113 909 1 1
RUNX1 FUT4 0 0 150 173 1 1
RUNX1 HIST1H2BM 0 600 0 600 1 1
RUNX1 IKZF3 270 0 108 374 1 1
RUNX1 TCF3 270 600 260 804 1 1
RUNX1 AMMECR1 0 0 157 156 1 1
RUNX1 BRCA1 229 0 59 245 1 2
RUNX1 ZNF354C 0 0 0 157 1 1
RUNX1 PAX9 0 0 0 189 1 1
RUNX1 MTA1 0 0 0 181 1 1
RUNX1 HOXB3 0 0 142 257 1 1
RUNX1 DLX2 0 0 0 202 1 1
RUNX1 SUCO 0 0 0 189 1 1
RUNX1 HDAC3 675 0 60 714 1 2
RUNX1 MYCN 0 0 150 214 1 1
RUNX1 SMAD4 0 900 122 917 1 2
RUNX1 AGO4 0 900 0 900 1 1
RUNX1 HIST1H2BH 0 600 0 600 1 1
RUNX1 FHL2 270 0 0 289 1 1
RUNX1 FOXM1 0 0 87 155 1 1
RUNX1 HOXA7 0 0 193 251 1 1
RUNX1 FGF21 0 0 0 187 1 2
RUNX1 ANXA5 0 0 108 187 1 2
RUNX1 ZBTB48 0 0 305 329 1 1
RUNX1 EPO 0 0 122 155 1 2
RUNX1 SIAH1 270 0 0 270 1 1
RUNX1 MAPKBP1 0 0 184 185 1 1
RUNX1 U2AF1L4 0 0 184 325 1 1
RUNX1 CREBBP 486 600 212 831 1 1
RUNX1 MOV10 0 900 0 903 1 1
RUNX1 KATNB1 0 0 0 222 1 1
RUNX1 BCL11B 0 0 206 282 1 1
RUNX1 ESRRA 0 0 0 207 1 1
RUNX1 RUNX1T1 487 800 605 957 1 1
RUNX1 NFE2 0 900 288 929 1 1
RUNX1 ZNF628 0 0 0 154 1 1
RUNX1 CREB1 0 0 180 182 1 2
RUNX1 STAG2 0 0 113 174 1 1
RUNX1 HIST2H2AC 0 600 0 600 1 1
RUNX1 IFNG 270 900 81 939 1 2
RUNX1 WWP1 270 0 0 301 1 1
RUNX1 GAPDH 0 0 160 182 1 2
RUNX1 PPP1R3E 0 0 0 244 1 1
RUNX1 PML 486 800 487 945 1 2
RUNX1 SMAD2 270 0 123 442 1 2
RUNX1 EBF1 0 0 129 217 1 1
RUNX1 HIST1H2AC 0 600 0 600 1 1
RUNX1 ELF1 270 600 0 721 1 1
RUNX1 ABL1 0 900 363 936 1 1
RUNX1 NF1 0 0 174 188 1 1
RUNX1 ERG 0 0 167 450 1 1
RUNX1 TCF7L2 0 0 0 193 1 1
RUNX1 ZIC1 0 0 0 248 1 1
RUNX1 EVI5 0 0 171 185 1 1
RUNX1 KITLG 0 0 184 208 1 1
RUNX1 ZGLP1 0 0 0 207 1 1
RUNX1 RORA 0 0 44 219 1 1
RUNX1 KMT2E 0 600 488 786 1 1
RUNX1 CBX6 0 600 0 600 1 1
RUNX1 BCL2L1 0 0 150 181 1 2
RUNX1 HMGB2 0 0 412 422 1 1
RUNX1 DNMT3B 0 0 347 366 1 1
RUNX1 KAT6A 678 0 373 810 1 1
RUNX1 KLF6 270 0 0 322 1 1
RUNX1 TNRC6B 0 900 0 900 1 1
RUNX1 SOX12 0 0 0 217 1 1
RUNX1 DNMT3A 0 0 372 380 1 2
RUNX1 AUTS2 0 600 82 621 1 1
RUNX1 CDC73 270 0 0 270 1 1
RUNX1 EGR1 0 0 170 215 1 2
RUNX1 H2AFV 0 600 0 600 1 1
RUNX1 CTNNB1 108 0 183 292 1 2
RUNX1 HRAS 0 0 292 333 1 2
RUNX1 HOXA4 0 0 160 167 1 1
RUNX1 ELK1 0 0 0 185 1 1
RUNX1 SLC5A7 0 0 0 642 1 1
RUNX1 BCAS1 0 0 183 183 1 1
RUNX1 SP1 270 0 95 323 1 2
RUNX1 NR1H3 0 0 0 151 1 1
RUNX1 SGCD 0 0 0 461 1 1
RUNX1 HIF1A 312 0 81 355 1 2
RUNX1 EN2 0 0 0 207 1 1
RUNX1 OAS1 0 0 0 160 1 1
RUNX1 PHC1 0 600 0 658 1 1
RUNX1 NEDD4 270 0 54 291 1 2
RUNX1 MLF2 0 0 0 279 1 1
RUNX1 PRKCB 0 900 0 901 1 2
RUNX1 ELK3 0 0 0 214 1 1
RUNX1 CTSL 0 650 0 650 1 2
RUNX1 PAX2 0 0 0 237 1 1
RUNX1 KIAA1429 270 0 0 270 1 1
RUNX1 GABPA 0 0 0 253 1 1
RUNX1 SUMO2 0 0 0 174 1 1
RUNX1 IL6 0 0 93 227 1 2
RUNX1 LYZ 0 0 0 161 1 1
RUNX1 ACAN 0 0 0 367 1 1
RUNX1 MPO 0 800 209 848 1 2
RUNX1 SUMO4 0 0 0 174 1 1
RUNX1 ETS2 0 0 140 400 1 1
RUNX1 BICC1 0 0 0 208 1 1
RUNX1 TCF15 0 0 0 150 1 1
RUNX1 THRA 0 0 0 184 1 1
RUNX1 OCLN 0 900 0 901 1 1
RUNX1 RPS6 0 0 295 295 1 2
RUNX1 CBX3 0 0 0 181 1 1
RUNX1 BRD2 0 600 70 630 1 1
RUNX1 KAT6B 270 0 90 333 1 1
RUNX1 PRMT1 270 800 400 914 1 1
RUNX1 NOTCH1 73 0 266 370 1 2
RUNX1 FGF13 0 0 49 162 1 1
RUNX1 CYR61 0 0 48 204 1 1
RUNX1 HIST1H4F 270 0 89 314 1 1
RUNX1 CXCR4 0 0 108 161 1 2
RUNX1 USP42 0 0 152 151 1 1
RUNX1 SGOL1 0 0 0 151 1 1
RUNX1 CDKN1A 0 0 180 248 1 2
RUNX1 SPP1 0 0 65 407 1 2
RUNX1 MBD3 0 0 0 181 1 1
RUNX1 ASXL1 0 0 468 468 1 1
RUNX1 AR 213 0 45 332 1 2
RUNX1 ETV4 0 0 106 240 1 1
RUNX1 RBM14 270 0 46 273 1 1
RUNX1 HIST1H2BL 0 600 0 600 1 1
RUNX1 H2AFB1 0 600 0 600 1 1
RUNX1 STK4 0 0 56 201 1 1
RUNX1 ZRSR2 0 0 143 166 1 1
RUNX1 BCR 0 0 217 217 1 2
RUNX1 RAB35 0 0 0 199 1 1
RUNX1 ESR2 0 0 0 151 1 1
RUNX1 PPP1R3D 0 0 0 422 1 1
RUNX1 ZBTB7B 0 0 0 332 1 1
RUNX1 PTPRC 0 0 212 413 1 1
RUNX1 SOX9 0 0 0 454 1 1
RUNX1 PTGER2 0 0 0 199 1 1
RUNX1 PBX1 0 0 323 352 1 1
RUNX1 CEBPE 0 0 135 205 1 1
RUNX1 CTBP1 270 800 325 910 1 1
RUNX1 PAX8 0 0 0 189 1 1
RUNX1 IL3 0 900 240 925 1 1
RUNX1 SP7 0 0 0 550 1 1
RUNX1 HDAC4 0 0 94 186 1 2
RUNX1 ZMYM2 0 0 306 306 1 1
RUNX1 PATZ1 0 0 0 460 1 1
RUNX1 SET 0 0 65 193 1 1
RUNX1 CLEC2D 0 0 0 183 1 1
RUNX1 SETD1A 0 600 63 609 1 1
RUNX1 CEBPA 270 800 504 926 1 1
RUNX1 SOX2 270 0 95 380 1 2
RUNX1 SP100 0 0 81 164 1 1
RUNX1 SUV39H1 486 0 829 908 1 1
RUNX1 SETBP1 0 0 287 286 1 1
RUNX1 ELF2 486 600 408 871 1 1
RUNX1 HIATL1 0 0 0 250 1 1
RUNX1 FOXG1 0 0 44 315 1 1
RUNX1 CLDN5 0 900 0 900 1 1
RUNX1 ACTB 0 0 141 203 1 2
RUNX1 CKMT1A 0 0 193 193 1 1
RUNX1 HOXA5 0 0 190 195 1 1
RUNX1 STUB1 486 0 112 598 1 2
RUNX1 DNMT1 270 0 155 401 1 2
RUNX1 SETD3 0 0 0 261 1 1
RUNX1 TLE1 297 0 0 748 1 1
RUNX1 TLE6 0 0 0 366 1 1
RUNX1 KMT2C 0 600 117 634 1 1
RUNX1 ANGPT1 0 0 134 156 1 1
RUNX1 SETSIP 0 0 0 173 1 1
RUNX1 PAX5 270 600 175 806 1 1
RUNX1 ETV3L 0 0 0 185 1 1
RUNX1 KLF15 0 0 0 225 1 1
RUNX1 JUNB 0 0 0 174 1 1
RUNX1 PBX3 0 0 115 153 1 1
RUNX1 SLC37A4 0 0 0 173 1 1
RUNX1 NCOA2 0 0 250 250 1 1
RUNX1 PRAM1 0 0 433 433 1 1
RUNX1 CDC20 0 0 88 151 1 1
RUNX1 PLS1 0 0 0 189 1 1
RUNX1 ZBTB16 0 0 388 420 1 1
RUNX1 ZBTB18 0 0 0 202 1 1
RUNX1 NR2F2 0 0 0 205 1 1
RUNX1 SERPINB2 0 0 0 244 1 1
RUNX1 WDR5 0 600 150 697 1 1
RUNX1 TAZ 213 0 0 376 1 1
RUNX1 CBFA2T2 678 0 150 739 1 1
RUNX1 TRIM17 0 0 385 394 1 1
RUNX1 DLL4 0 0 0 200 1 1
RUNX1 GP1BA 0 900 47 902 1 1
RUNX1 GOLGB1 0 0 0 231 1 1
RUNX1 BATF 0 0 0 229 1 1
RUNX1 ITPR3 0 0 324 323 1 1
RUNX1 JUN 486 0 447 714 1 2
RUNX1 LCK 0 0 157 221 1 1
RUNX1 CCRL2 0 0 0 168 1 1
RUNX1 TLE4 0 0 0 657 1 1
RUNX1 PHC2 0 600 0 625 1 1
RUNX1 FGF6 0 0 0 188 1 1
RUNX1 SHH 0 0 75 217 1 2
RUNX1 SOX17 0 0 73 165 1 1
RUNX1 WBP5 0 0 170 169 1 1
RUNX1 IL7R 0 0 89 240 1 1
RUNX1 BMI1 0 0 211 384 1 1
RUNX1 PARP14 0 0 0 179 1 1
RUNX1 ENSG00000269095 0 0 0 151 1 1
RUNX1 MNAT1 0 900 0 900 1 1
RUNX1 RING1 0 600 51 674 1 1
RUNX1 SMAD1 270 0 0 349 1 2
RUNX1 FAM84B 0 0 0 211 1 1
RUNX1 ARID1B 0 600 55 636 1 1
RUNX1 CSTF3 0 0 0 223 1 1
RUNX1 HIST1H2BK 0 600 0 600 1 1
RUNX1 RUNX3 0 900 460 904 1 1
RUNX1 SLAMF1 0 0 66 169 1 1
RUNX1 ETV1 0 0 0 275 1 1
RUNX1 UHRF2 270 0 0 271 1 1
RUNX1 SUMO3 0 0 0 198 1 1
RUNX1 ZNF217 0 0 50 226 1 1
RUNX1 GRB7 0 0 0 189 1 1
RUNX1 BCL11A 0 0 112 197 1 1
RUNX1 SKP2 0 0 102 160 1 2
RUNX1 CBFA2T3 678 0 397 807 1 1
RUNX1 IGHV4-38-2 0 0 170 169 1 1
RUNX1 PHF8 0 0 0 440 1 1
RUNX1 CENPF 0 0 100 196 1 1
RUNX1 ZNF131 270 0 0 282 1 1
RUNX1 NR2E1 0 0 0 190 1 1
RUNX1 HLX 0 0 0 153 1 1
RUNX1 ZIC5 0 0 0 248 1 1
RUNX1 WDR47 0 0 0 277 1 1
RUNX1 FOXP1 0 0 218 308 1 1
RUNX1 KDM2A 0 0 0 188 1 1
RUNX1 FOXI1 0 0 0 167 1 1
RUNX1 HIST2H3PS2 0 0 194 210 1 1
RUNX1 LYZL2 0 0 0 192 1 1
RUNX1 IL2RG 0 0 0 158 1 1
RUNX1 NR3C1 0 0 74 203 1 1
RUNX1 ISM1 0 0 0 250 1 1
RUNX1 H2AFZ 0 600 0 600 1 1
RUNX1 SMARCB1 270 600 329 808 1 1
RUNX1 PPP1R10 0 0 0 642 1 1
RUNX1 TRIM5 270 0 0 296 1 1
RUNX1 SCMH1 0 600 0 600 1 1
RUNX1 GATA4 0 0 0 268 1 2
RUNX1 ETV5 0 0 0 185 1 1
RUNX1 SEPT9 0 0 47 214 1 1
RUNX1 SMARCA2 0 600 0 632 1 1
RUNX1 STK16 0 0 0 339 1 1
RUNX1 PPARA 0 0 0 151 1 2
RUNX1 TEK 0 0 141 210 1 1
RUNX1 KCTD6 0 900 0 900 1 1
RUNX1 PCGF1 0 0 112 157 1 1
RUNX1 DAB2 0 0 0 217 1 1
RUNX1 NANOG 0 0 74 184 1 2
RUNX1 ITPR1 0 0 291 290 1 2
RUNX1 TRAF6 270 0 74 296 1 2
RUNX1 GFI1B 0 0 246 378 1 1
RUNX1 ETS1 800 0 955 993 1 1
RUNX1 CRABP1 0 0 398 403 1 1
RUNX1 HNF1A 0 0 118 158 1 1
RUNX1 BMP2 0 0 0 210 1 1
RUNX1 HCFC1 0 0 0 181 1 1
RUNX1 CSNK2A2 0 600 0 603 1 1
RUNX1 THADA 0 0 0 188 1 1
RUNX1 TNRC6C 0 900 0 900 1 1
RUNX1 MLLT10 0 0 310 309 1 1
RUNX1 ZNF687 0 0 502 510 1 1
RUNX1 PRMT6 0 600 349 733 1 1
RUNX1 CLEC2B 0 0 0 207 1 1
RUNX1 EP300 487 600 784 953 1 2
RUNX1 GSG1L 0 0 0 248 1 1
RUNX1 LEF1 0 650 210 731 1 1
RUNX1 MLLT4 0 0 194 194 1 1
RUNX1 PLS3 0 0 0 238 1 1
RUNX1 SPARC 0 0 0 173 1 2
RUNX1 SMAD3 486 900 729 985 1 2
RUNX1 RNF44 270 0 0 270 1 1
RUNX1 YAF2 0 600 0 600 1 1
RUNX1 SMARCE1 0 600 48 664 1 1
RUNX1 FOXI3 0 0 0 167 1 1
RUNX1 NR3C2 0 0 0 151 1 1
RUNX1 AFF4 0 0 0 205 1 1
RUNX1 NODAL 0 0 0 206 1 1
RUNX1 GATA1 0 600 659 911 1 1
RUNX1 PAX6 0 0 0 174 1 1
RUNX1 DCTN3 0 0 0 185 1 1
RUNX1 H2AFX 0 600 0 600 1 1
RUNX1 CDK6 632 600 93 877 1 2
RUNX1 KMT2B 0 600 124 634 1 1
RUNX1 WNT16 0 0 0 250 1 1
RUNX1 EPHA4 0 0 0 194 1 1
RUNX1 HIST1H2BO 0 600 0 600 1 1
RUNX1 SLC37A2 0 0 0 173 1 1
RUNX1 IDH1 0 0 358 358 1 1
RUNX1 HOXB2 0 0 84 183 1 1
RUNX1 CD33 0 0 195 195 1 1
RUNX1 FGF17 0 0 46 191 1 1
RUNX1 FEV 0 0 0 247 1 1
RUNX1 MEIS1 0 0 422 458 1 1
RUNX1 SBNO1 0 0 0 290 1 1
RUNX1 PPP1R3B 0 0 0 429 1 1
RUNX1 CCND1 213 600 167 721 1 2
RUNX1 TIMD4 0 0 0 422 1 1
RUNX1 FLI1 0 800 181 923 1 1
RUNX1 ZNF75D 0 0 166 210 1 1
RUNX1 AHNAK 0 0 0 193 1 1
RUNX1 HDAC7 0 0 140 195 1 1
RUNX1 GCM2 0 0 123 226 1 1
RUNX1 FOXC2 0 0 45 165 1 1
RUNX1 BAALC 0 0 459 459 1 1
RUNX1 CD19 0 0 134 207 1 1
RUNX1 KLF1 0 0 287 313 1 1
RUNX1 TOM1L2 0 0 206 206 1 1
RUNX1 NTRK1 0 0 134 170 1 1
RUNX1 UXT 270 0 0 270 1 1
RUNX1 EGR2 0 0 81 191 1 1
RUNX1 PIK3C2B 0 0 181 198 1 1
RUNX1 DMTF1 0 0 194 206 1 1
RUNX1 REM1 0 0 0 170 1 1
RUNX1 KAT2B 0 600 75 620 1 1
RUNX1 HIATL2 0 0 0 250 1 1
RUNX1 HIST2H2BE 0 600 0 600 1 1
RUNX1 ETV6 0 0 416 532 1 1
RUNX1 LYL1 0 0 263 426 1 1
RUNX1 PGR 0 0 0 241 1 1
RUNX1 DOT1L 0 0 194 194 1 1
RUNX1 CDK1 270 0 54 315 1 2
RUNX1 NCOR1 270 0 752 811 1 1
RUNX1 DEK 0 650 304 745 1 1
RUNX1 NKX2-5 0 0 81 162 1 1
RUNX1 PECAM1 0 0 96 297 1 1
RUNX1 GFI1 0 650 323 804 1 1
RUNX1 ARID4A 0 0 218 218 1 1
RUNX1 TAL1 486 800 390 967 1 1
RUNX1 MECOM 0 800 466 890 1 1
RUNX1 LCP1 0 0 69 477 1 1
RUNX1 ZFYVE9 0 0 329 329 1 1
RUNX1 FOXP4 0 0 134 233 1 1
RUNX1 POU5F1 0 0 136 223 1 2
RUNX1 BMP5 0 0 0 177 1 1
RUNX1 CDX4 0 0 124 226 1 1
RUNX1 RHEB 0 0 306 346 1 2
RUNX1 TOB2 0 0 0 353 1 1
RUNX1 TNRC6A 0 900 0 900 1 1
RUNX1 MYB 0 800 315 944 1 1
RUNX1 FOXA2 0 0 0 160 1 1
RUNX1 CD38 0 0 141 180 1 2
RUNX1 RNF38 270 0 0 270 1 1
RUNX1 GPAM 0 900 0 900 1 1
RUNX1 TRPS1 0 0 54 242 1 1
RUNX1 RANBP3L 0 0 0 179 1 1
RUNX1 CTLA4 0 900 44 915 1 2
RUNX1 ETV2 0 0 42 311 1 1
RUNX1 PAX3 0 0 0 159 1 1
RUNX1 PPP1R2 0 0 0 208 1 1
RUNX1 ITCH 0 900 0 904 1 1
RUNX1 RBBP7 0 0 0 178 1 1
RUNX1 ETV3 0 0 90 306 1 1
RUNX1 RCAN1 0 0 57 203 1 2
RUNX1 CARF 0 0 0 188 1 1
RUNX1 RTL1 0 0 0 161 1 1
RUNX1 CD44 0 0 62 222 1 2
RUNX1 MEF2C 0 0 123 211 1 1
RUNX1 HOXA3 0 0 66 165 1 1
RUNX1 SIN3A 270 600 275 927 1 1
RUNX1 SERPINB13 0 900 0 900 1 1
RUNX1 GFER 0 0 0 190 1 1
RUNX1 MYBBP1A 0 0 0 288 1 1
RUNX1 MTMR11 0 0 162 161 1 1
RUNX1 NR4A2 270 0 46 649 1 1
RUNX1 VDR 270 0 95 494 1 2
RUNX1 WISP1 0 0 0 199 1 1
RUNX1 SMARCD1 0 600 0 658 1 1
RUNX1 HLA-DMA 270 0 0 270 1 1
RUNX1 CSF1R 462 800 193 914 1 1
RUNX1 SHOX2 0 0 0 190 1 1
RUNX1 SOCS4 0 900 0 900 1 1
RUNX1 MAPK1 270 0 63 340 1 2
RUNX1 ARNTL 0 0 0 252 1 1
RUNX1 FCHO2 0 0 181 198 1 1
RUNX1 CCND3 213 600 113 712 1 1
RUNX1 ENSG00000142539 0 0 0 156 1 1
RUNX1 ESRRB 0 0 0 235 1 1
RUNX1 HIST1H2AJ 0 600 0 600 1 1
RUNX1 CASK 0 0 0 550 1 1
RUNX1 CDH5 0 0 74 350 1 1
RUNX1 SSU72 0 0 0 189 1 1
RUNX1 FOXK2 0 0 0 153 1 1
RUNX1 FGF2 0 0 95 211 1 2
RUNX1 REST 0 0 71 169 1 2
RUNX1 SRSF2 0 0 209 384 1 1
RUNX1 KMT2A 270 600 293 775 1 1
RUNX1 CSNK2A1 0 600 0 603 1 1
RUNX1 IFI16 0 0 0 173 1 1
RUNX1 TLE2 213 0 0 479 1 1
RUNX1 CCND2 213 600 92 701 1 1
RUNX1 U2AF2 0 0 0 216 1 1
RUNX1 PLXNB2 0 0 0 188 1 1
RUNX1 NR0B1 0 0 0 151 1 1
RUNX1 PPTC7 0 0 0 286 1 1
RUNX1 ARX 0 0 0 173 1 1
RUNX1 FOXJ1 0 0 0 201 1 1
RUNX1 CDYL2 0 0 112 161 1 1
RUNX1 CD34 0 0 394 443 1 2
RUNX1 HMGA2 270 0 72 409 1 1
RUNX1 ACVR1B 0 0 66 159 1 1
RUNX1 FANCD2 270 0 0 270 1 1
RUNX1 AGO3 0 900 0 900 1 1
RUNX1 ZNF521 0 0 108 251 1 1
RUNX1 NR1I2 0 0 0 170 1 1
RUNX1 HIST1H2BN 0 600 0 600 1 1
RUNX1 RBBP5 0 600 47 602 1 1
RUNX1 ZNF177 0 0 181 195 1 1
RUNX1 FGF3 0 0 91 182 1 1
RUNX1 SUPT3H 0 0 103 305 1 1
RUNX1 ID2 0 0 52 151 1 1
RUNX1 WWOX 0 0 0 152 1 1
RUNX1 BCL6 0 0 125 266 1 1
RUNX1 ATOH1 0 0 0 213 1 1
RUNX1 KMT2D 0 600 134 638 1 1
RUNX1 CEBPG 0 0 0 226 1 1
RUNX1 FGFR1 0 0 123 212 1 1
RUNX1 KLF4 0 0 95 201 1 2
RUNX1 SATB1 0 0 142 245 1 1
RUNX1 IKBKB 0 0 454 466 1 2
RUNX1 FOXA1 0 0 48 167 1 1
RUNX1 PRDM16 0 0 136 151 1 1
RUNX1 RSPO3 0 900 0 900 1 1
RUNX1 UCKL1 0 0 228 227 1 1
RUNX1 HOXA10 0 0 246 262 1 1
RUNX1 HIST1H2BA 0 600 0 600 1 1
RUNX1 CD4 0 0 144 285 1 2
RUNX1 PPARG 0 0 81 231 1 2
RUNX1 AKT1 0 0 143 204 1 2
RUNX1 SPIB 0 0 0 156 1 1
RUNX1 PTP4A3 0 0 203 203 1 1
RUNX1 DDX10 0 0 241 253 1 1
RUNX1 TEAD2 116 0 154 220 1 1
RUNX1 CSF2 0 900 170 915 1 1
RUNX1 PHF2 0 0 0 440 1 1
RUNX1 STK3 0 0 0 189 1 1
RUNX1 NUP214 0 0 247 246 1 1
RUNX1 CDKN1B 0 0 114 169 1 2
RUNX1 NIPAL3 0 0 0 206 1 1
RUNX1 MLF1 0 0 95 320 1 1
RUNX1 CTCF 0 0 113 217 1 1
RUNX1 USP7 0 0 291 290 1 1
RUNX1 PF4 0 900 91 905 1 1
RUNX1 TGFB1 0 0 0 254 1 2
RUNX1 STAT5B 0 0 142 227 1 1
RUNX1 AES 192 0 49 470 1 1
RUNX1 PPM1D 0 0 167 176 1 1
RUNX1 RAC2 0 0 68 181 1 1
RUNX1 ELK4 0 0 56 247 1 1
RUNX1 CBX2 0 600 0 600 1 1
RUNX1 SLC37A1 0 0 0 173 1 1
RUNX1 NFATC2 129 600 150 696 1 1
RUNX1 KDR 0 0 123 358 1 2
RUNX1 DMP1 0 0 95 151 1 1
RUNX1 IL4I1 0 0 0 173 1 1
RUNX1 HIAT1 0 0 0 250 1 1
RUNX1 RNF2 0 600 0 671 1 1
RUNX1 HIST1H2BJ 0 600 0 600 1 1
RUNX1 ANPEP 0 0 139 188 1 1
RUNX1 SRSF8 0 0 0 254 1 1
RUNX1 FOXP3 270 800 615 984 1 2
RUNX1 H2AFJ 0 600 0 600 1 1
RUNX1 TLX3 0 0 151 219 1 1
RUNX1 POLD3 0 0 0 181 1 1
RUNX1 RNF139 0 0 170 169 1 1
RUNX1 TCF12 270 600 427 821 1 1
RUNX1 STAT6 0 0 0 152 1 1
RUNX1 HOXB6 0 0 165 166 1 1
RUNX1 LGALS3 0 900 0 903 1 2
RUNX1 CDKN3 0 0 134 161 1 1
RUNX1 TNFRSF18 0 900 74 917 1 1
RUNX1 FLT1 0 0 46 178 1 1
RUNX1 LDB2 0 0 447 519 1 1
RUNX1 ACTL6A 0 600 0 607 1 1
RUNX1 IRF8 0 0 113 266 1 1
RUNX1 SRC 0 800 82 838 1 2
RUNX1 MPHOSPH8 0 0 122 170 1 1
RUNX1 TFCP2 0 0 0 189 1 1
RUNX1 MKL1 0 0 124 210 1 1
RUNX1 SMARCC1 270 600 66 743 1 1
RUNX1 SIN3B 0 600 0 750 1 1
RUNX1 RAG1 270 0 66 636 1 1
RUNX1 BGLAP 0 0 171 590 1 1
RUNX1 ZFPM2 0 0 357 368 1 1
RUNX1 TNFSF11 0 0 61 155 1 2
RUNX1 DPY30 0 600 0 600 1 1
RUNX1 LIFR 0 900 0 900 1 1
RUNX1 FOXO3 0 0 430 498 1 2
RUNX1 GATA5 0 0 47 242 1 1
RUNX1 CBFB 983 900 581 999 1 1
RUNX1 PBRM1 0 600 0 606 1 1
RUNX1 BLK 0 900 90 907 1 1
RUNX1 CDKN2A 0 0 222 222 1 2
RUNX1 MGP 0 0 0 190 1 1
RUNX1 RBL2 0 0 0 159 1 1
RUNX1 ZIC2 0 0 0 248 1 1
RUNX1 CEBPB 847 0 282 895 1 2
RUNX1 UBE2L6 270 0 0 270 1 1
RUNX1 PIK3CD 0 0 0 154 1 1
RUNX1 EVX2 0 0 0 248 1 1
RUNX1 TWIST2 0 0 0 211 1 1
RUNX1 HDAC1 835 800 171 976 1 2
RUNX1 CBX8 0 600 67 610 1 1
RUNX1 CSF1 0 0 103 169 1 1
RUNX1 FGF11 0 0 0 188 1 1
RUNX1 PHC3 0 600 0 625 1 1
RUNX1 HDAC9 0 0 153 208 1 1
RUNX1 REL 0 0 138 191 1 2
RUNX1 CEBPZ 0 0 0 208 1 1
RUNX1 ELF3 0 0 150 182 1 1
RUNX1 GNA15 0 0 0 161 1 1
RUNX1 ESRRG 0 0 0 214 1 1
RUNX1 ENSG00000160201 0 0 172 315 1 1
RUNX1 FGF19 0 0 0 188 1 1
RUNX1 ZSCAN26 0 0 0 157 1 1
RUNX1 MLLT3 0 0 417 455 1 1
RUNX1 PRKCQ 0 900 83 904 1 2
RUNX1 ENSG00000270011 0 0 181 195 1 1
RUNX1 FGF22 0 0 0 188 1 1
RUNX1 IHH 0 0 0 189 1 1
RUNX1 NR2C2 0 0 71 216 1 1
RUNX1 COPRS 270 0 0 270 1 1
RUNX1 EBF3 0 0 75 168 1 1
RUNX1 HDAC11 270 0 0 332 1 1
RUNX1 TET1 0 0 167 167 1 1
RUNX1 RAD21 0 0 53 153 1 1
RUNX1 SETD1B 0 600 0 600 1 1
RUNX1 CD28 0 0 0 191 1 1
RUNX1 HIST1H2BB 0 600 0 600 1 1
RUNX1 ASH2L 0 600 59 665 1 1
RUNX1 IL2 486 900 63 952 1 1
RUNX1 THBS1 0 900 0 903 1 1
RUNX1 SMARCD3 0 600 0 649 1 1
RUNX1 NR6A1 0 0 0 151 1 1
RUNX1 ERF 0 0 0 269 1 1
RUNX1 CDKN2B 0 0 198 198 1 1
RUNX1 MAPK11 0 0 0 161 1 1
RUNX1 FLT4 0 0 0 212 1 1
RUNX1 ST6GAL2 0 0 0 642 1 1
RUNX1 MED1 0 0 0 151 1 1
RUNX1 RXRB 0 0 0 200 1 1
RUNX1 FOXC1 0 0 95 208 1 1
RUNX1 MYH11 0 0 414 414 1 1
RUNX1 MATK 0 0 181 181 1 1
RUNX1 SOCS3 0 900 0 904 1 1
RUNX1 U2AFBP 0 0 172 315 1 1
RUNX1 THRB 0 0 0 184 1 1
RUNX1 FOS 486 0 150 550 1 2
RUNX1 BSX 0 0 0 157 1 1
RUNX1 TWIST1 0 0 46 220 1 1
RUNX1 PTPN11 0 800 181 835 1 1
RUNX1 LMO1 0 600 57 633 1 1
RUNX1 RXRA 0 0 56 213 1 1
RUNX1 LMO2 0 600 460 836 1 1
RUNX1 STAT5A 0 0 142 301 1 1
RUNX1 KDM2B 0 0 90 229 1 1
RUNX1 E2F1 0 0 90 182 1 2
RUNX1 FOXP2 0 0 46 155 1 1
RUNX1 NRAS 0 0 377 413 1 1
RUNX1 CDK9 466 0 0 488 1 1
RUNX1 DTX2 270 0 94 310 1 1
RUNX1 FOXO1 0 0 63 195 1 2
RUNX1 KRAS 0 0 112 301 1 2
RUNX1 ZIC3 0 0 0 208 1 1
RUNX1 MN1 0 0 493 493 1 1
RUNX1 MMP13 0 0 46 161 1 2
RUNX1 CSNK2B 0 600 0 600 1 1
RUNX1 NUMA1 0 0 350 349 1 1
RUNX1 RAG2 0 0 53 200 1 1
RUNX1 IFT27 0 0 0 152 1 1
RUNX1 RARA 270 0 464 639 1 2
RUNX1 SLC37A3 0 0 0 642 1 1
RUNX1 TBX21 0 800 45 936 1 1
RUNX1 DLX1 0 0 0 223 1 1
RUNX1 RPS18 0 0 0 218 1 1
RUNX1 ELANE 0 0 410 410 1 1
RUNX1 THPO 0 0 208 224 1 1
RUNX1 NR2E3 0 0 0 151 1 1
RUNX1 LDB1 0 600 261 738 1 1
RUNX1 ARID1A 0 600 0 635 1 1
RUNX1 PCDH11X 0 0 46 372 1 1
RUNX1 TEAD4 113 0 96 164 1 1
RUNX1 VPS33B 0 0 156 155 1 1
RUNX1 RIN3 0 0 0 154 1 1
RUNX1 VAV1 0 0 125 206 1 1
RUNX1 ANTXR2 0 0 0 150 1 1
RUNX1 AGL 0 0 0 210 1 1
RUNX1 TET2 0 0 459 459 1 2
RUNX1 ZFPM1 0 600 134 700 1 1
RUNX1 NKX2-1 270 0 0 287 1 1
RUNX1 TGFBR1 0 0 71 163 1 1
RUNX1 CHIC2 0 0 218 218 1 1
RUNX1 MYBL2 0 0 70 231 1 1
RUNX1 ELN 0 0 57 196 1 1
RUNX1 MPL 0 0 279 306 1 1
RUNX1 MIB1 0 0 0 153 1 1
RUNX1 ATOH7 0 0 0 213 1 1
RUNX1 GATA6 0 0 0 237 1 1
RUNX1 KCNH8 0 0 0 219 1 1
RUNX1 YAP1 775 600 137 926 1 2
RUNX1 SOX6 0 0 45 150 1 1
RUNX1 HIPK2 270 900 180 935 1 2
RUNX1 ITGB3 0 0 88 172 1 1
RUNX1 MLLT1 0 0 392 405 1 1
RUNX1 CTSK 0 650 0 671 1 2
RUNX1 ACTL6B 0 600 0 607 1 1
RUNX1 EN1 0 0 57 220 1 1
RUNX1 ESR1 0 600 92 678 1 2
RUNX1 RBBP4 0 0 73 227 1 1
RUNX1 T 0 0 0 217 1 1
RUNX1 SMARCD2 0 600 0 644 1 1
RUNX1 SH3D19 0 0 500 499 1 1
RUNX1 SMAD7 0 0 134 203 1 1
RUNX1 ITGAM 0 0 159 216 1 1
RUNX1 GATA2 0 800 655 945 1 1
RUNX1 ELF4 486 0 81 571 1 1
RUNX1 SMARCA4 270 600 134 759 1 1
RUNX1 CR1 0 900 0 900 1 1
RUNX1 TLE3 0 0 57 663 1 1
RUNX1 EOMES 0 0 0 153 1 1
RUNX1 HIST1H2AD 0 600 0 600 1 1
RUNX1 SPI1 270 800 600 951 1 1
RUNX1 CD79A 0 0 96 180 1 1
RUNX1 CSF3R 0 650 109 707 1 1
RUNX1 RORC 0 0 0 189 1 1
RUNX1 NBEAL2 0 0 260 276 1 1
RUNX1 PPP1R8 0 0 0 332 1 1
RUNX1 PAX1 0 0 0 230 1 1
RUNX1 LPXN 0 0 48 174 1 1
RUNX1 KAT5 0 0 181 194 1 1
RUNX1 MAPK14 0 0 0 161 1 2
RUNX1 PRAME 0 0 357 357 1 1
RUNX1 NUP98 0 0 400 400 1 1
RUNX1 KIT 0 0 395 456 1 2
RUNX1 COMMD3-BMI1 0 0 210 383 1 1
RUNX1 PHF6 0 0 124 178 1 1
RUNX1 BMP4 0 0 122 312 1 1
RUNX1 WT1 0 0 379 390 1 1
RUNX1 H2BFS 0 600 0 600 1 1
RUNX1 RARB 0 0 70 177 1 1
RUNX1 AGO1 0 900 0 900 1 1
RUNX1 COL10A1 0 0 0 301 1 1
RUNX1 PCDH9 0 0 64 649 1 1
RUNX1 HCFC2 0 0 0 165 1 1
RUNX1 NFATC1 129 0 45 187 1 2
RUNX1 MYOD1 270 0 103 386 1 1
RUNX1 NTRK3 0 0 125 207 1 1
RUNX1 PTEN 0 0 184 185 1 2
RUNX1 IRF4 0 0 94 268 1 1
RUNX1 ARID2 0 600 0 608 1 1
RUNX1 VEGFA 0 0 123 201 1 2
RUNX1 MTA2 0 0 0 181 1 1
RUNX1 NPM1 0 0 493 493 1 1
RUNX1 FLT3 0 0 517 523 1 2
RUNX1 RBPJ 0 0 70 168 1 1
RUNX1 COL1A1 0 0 59 223 1 2
RUNX1 RYBP 0 600 0 600 1 1
RUNX1 HHEX 0 0 0 263 1 1
RUNX1 EFNB2 0 0 0 303 1 1
RUNX1 CDK7 0 900 45 907 1 1
RUNX1 LYZL1 0 0 0 192 1 1
RUNX1 SP110 0 0 136 169 1 1
RUNX1 FOSL2 0 0 0 234 1 1
RUNX1 IKZF1 270 0 261 607 1 1
RUNX1 NR1H4 0 0 0 151 1 1
RUNX1 TJP1 0 900 0 900 1 1
RUNX1 RXRG 0 0 0 200 1 1
RUNX1 SMARCC2 0 600 0 672 1 1
RUNX1 CTSG 0 0 435 449 1 1
RUNX1 FGF12 0 0 0 188 1 1
RUNX1 SOX10 0 0 0 302 1 1
RUNX1 ZNF263 0 0 0 154 1 1
RUNX1 SMAD5 270 0 73 364 1 1
RUNX1 TEAD1 0 0 212 212 1 1
RUNX1 ITGA2B 0 900 261 931 1 1
RUNX1 JMJD1C 0 0 58 189 1 1
RUNX1 ZIC4 0 0 0 248 1 1
RUNX1 AXIN1 0 900 55 903 1 1
RUNX1 IDH2 0 0 309 313 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0005524 Molecular Function ATP binding enables IEA
GO:0001228 Molecular Function DNA-binding transcription activator activity, RNA polymerase II-specific enables IDA
GO:0001228 Molecular Function DNA-binding transcription activator activity, RNA polymerase II-specific enables IMP
GO:0000981 Molecular Function DNA-binding transcription factor activity, RNA polymerase II-specific enables IBA
GO:0000981 Molecular Function DNA-binding transcription factor activity, RNA polymerase II-specific enables ISA
GO:0000978 Molecular Function RNA polymerase II cis-regulatory region sequence-specific DNA binding enables IBA
GO:0000978 Molecular Function RNA polymerase II cis-regulatory region sequence-specific DNA binding enables IDA
GO:0000977 Molecular Function RNA polymerase II transcription regulatory region sequence-specific DNA binding enables IDA
GO:0000977 Molecular Function RNA polymerase II transcription regulatory region sequence-specific DNA binding enables IMP
GO:0005515 Molecular Function protein binding enables IPI
GO:0000976 Molecular Function transcription cis-regulatory region binding enables IDA
GO:0061026 Biological Process cardiac muscle tissue regeneration involved_in ISS
GO:0002062 Biological Process chondrocyte differentiation involved_in IBA
GO:0071425 Biological Process hematopoietic stem cell proliferation involved_in TAS
GO:0030097 Biological Process hemopoiesis involved_in IBA
GO:0030097 Biological Process hemopoiesis involved_in IDA
GO:0002573 Biological Process myeloid leukocyte differentiation involved_in IMP
GO:0043371 Biological Process negative regulation of CD4-positive, alpha-beta T cell differentiation involved_in ISS
GO:0000122 Biological Process negative regulation of transcription by RNA polymerase II involved_in ISS
GO:0030182 Biological Process neuron differentiation involved_in IBA
GO:0001503 Biological Process ossification involved_in IBA
GO:0048935 Biological Process peripheral nervous system neuron development involved_in TAS
GO:0043378 Biological Process positive regulation of CD8-positive, alpha-beta T cell differentiation involved_in ISS
GO:0045893 Biological Process positive regulation of DNA-templated transcription involved_in IDA
GO:0045766 Biological Process positive regulation of angiogenesis involved_in ISS
GO:0032967 Biological Process positive regulation of collagen biosynthetic process involved_in ISS
GO:1903055 Biological Process positive regulation of extracellular matrix organization involved_in ISS
GO:0030854 Biological Process positive regulation of granulocyte differentiation involved_in IMP
GO:0032743 Biological Process positive regulation of interleukin-2 production involved_in IMP
GO:0045944 Biological Process positive regulation of transcription by RNA polymerase II involved_in IDA
GO:0045944 Biological Process positive regulation of transcription by RNA polymerase II involved_in IMP
GO:0060043 Biological Process regulation of cardiac muscle cell proliferation acts_upstream_of ISS
GO:0045595 Biological Process regulation of cell differentiation involved_in IBA
GO:1905203 Biological Process regulation of connective tissue replacement involved_in ISS
GO:0010755 Biological Process regulation of plasminogen activation acts_upstream_of_or_within ISS
GO:0006357 Biological Process regulation of transcription by RNA polymerase II involved_in IBA
GO:0000785 Cellular Component chromatin part_of ISA
GO:0016513 Cellular Component core-binding factor complex part_of TAS
GO:0043231 Cellular Component intracellular membrane-bounded organelle located_in IDA
GO:0005654 Cellular Component nucleoplasm located_in IDA
GO:0005654 Cellular Component nucleoplasm located_in TAS
GO:0005634 Cellular Component nucleus located_in IDA
Pathways
Name DB ID
Developmental Biology Reactome R-HSA-1266738
Signaling by NOTCH Reactome R-HSA-157118
Signal Transduction Reactome R-HSA-162582
Disease Reactome R-HSA-1643685
Pre-NOTCH Transcription and Translation Reactome R-HSA-1912408
Pre-NOTCH Expression and Processing Reactome R-HSA-1912422
Generic Transcription Pathway Reactome R-HSA-212436
Transport of small molecules Reactome R-HSA-382551
Transport of bile salts and organic acids, metal ions and amine compounds Reactome R-HSA-425366
SLC-mediated transmembrane transport Reactome R-HSA-425407
Organic cation transport Reactome R-HSA-549127
Organic cation/anion/zwitterion transport Reactome R-HSA-549132
Infectious disease Reactome R-HSA-5663205
RNA Polymerase II Transcription Reactome R-HSA-73857
Gene expression (Transcription) Reactome R-HSA-74160
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) Reactome R-HSA-8877330
Transcriptional regulation by RUNX3 Reactome R-HSA-8878159
Transcriptional regulation by RUNX2 Reactome R-HSA-8878166
Transcriptional regulation by RUNX1 Reactome R-HSA-8878171
RUNX1 regulates estrogen receptor mediated transcription Reactome R-HSA-8931987
Regulation of RUNX1 Expression and Activity Reactome R-HSA-8934593
RUNX1 regulates expression of components of tight junctions Reactome R-HSA-8935964
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function Reactome R-HSA-8936459
ESR-mediated signaling Reactome R-HSA-8939211
RUNX1 regulates transcription of genes involved in differentiation of HSCs Reactome R-HSA-8939236
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes Reactome R-HSA-8939242
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Reactome R-HSA-8939243
RUNX1 regulates transcription of genes involved in BCR signaling Reactome R-HSA-8939245
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells Reactome R-HSA-8939246
RUNX1 regulates transcription of genes involved in interleukin signaling Reactome R-HSA-8939247
RUNX1 regulates transcription of genes involved in WNT signaling Reactome R-HSA-8939256
RUNX2 regulates genes involved in differentiation of myeloid cells Reactome R-HSA-8941333
RUNX3 regulates p14-ARF Reactome R-HSA-8951936
Signaling by Nuclear Receptors Reactome R-HSA-9006931
Estrogen-dependent gene expression Reactome R-HSA-9018519
Transcriptional regulation of granulopoiesis Reactome R-HSA-9616222
SARS-CoV-1 Infection Reactome R-HSA-9678108
SARS-CoV Infections Reactome R-HSA-9679506
SARS-CoV-1-host interactions Reactome R-HSA-9692914
SARS-CoV-1 activates/modulates innate immune responses Reactome R-HSA-9692916
Viral Infection Pathways Reactome R-HSA-9824446
Hematopoietic stem cell differentiation (WP2849) WikiPathways WP2849_r117150
Dual hijack model of Vif in HIV infection (WP3300) WikiPathways WP3300_r102277
Th17 cell differentiation pathway (WP5130) WikiPathways WP5130_r123523
Transcripts
Accession Version MolecularType Name NCBI Comments
XM_011529768 3 mRNA transcript variant X11 NC_000021 Reference
XM_011529767 3 mRNA transcript variant X4 NC_000021 Reference
XM_005261069 5 mRNA transcript variant X7 NC_000021 Reference
NM_001754 5 mRNA transcript variant 1 NC_000021 Reference
XM_047441015 1 mRNA transcript variant X13 NC_000021 Reference
XM_047441010 1 mRNA transcript variant X6 NC_000021 Reference
XM_047441012 1 mRNA transcript variant X9 NC_000021 Reference
XM_011529766 3 mRNA transcript variant X2 NC_000021 Reference
XM_047441014 1 mRNA transcript variant X12 NC_000021 Reference
XM_047441009 1 mRNA transcript variant X5 NC_000021 Reference
XM_047441011 1 mRNA transcript variant X8 NC_000021 Reference
XM_047441007 1 mRNA transcript variant X1 NC_000021 Reference
XM_047441013 1 mRNA transcript variant X10 NC_000021 Reference
XM_005261068 4 mRNA transcript variant X3 NC_000021 Reference
NM_001001890 3 mRNA transcript variant 2 NC_000021 Reference
XM_011529770 3 mRNA transcript variant X15 NC_000021 Reference
NM_001122607 2 mRNA transcript variant 3 NC_000021 Reference
XM_047441016 1 mRNA transcript variant X14 NC_000021 Reference