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MTMR3

myotubularin related protein 3
General Information
Name myotubularin related protein 3
Alias
  • myotubularin-related protein 3
  • FYVE (Fab1 YGLO23 Vsp27 EEA1 domain) dual-specificity protein phosphatase
  • FYVE domain-containing dual specificity protein phosphatase 1
  • phosphatidylinositol-3,5-bisphosphate 3-phosphatase
  • phosphatidylinositol-3-phosphate phosphatase
  • zinc finger FYVE domain-containing protein 10
  • zinc finger, FYVE domain containing 10
Gene_family Myotubularins|Zinc fingers FYVE-type|Phosphoinositide phosphatases|MicroRNA protein coding host genes
organism Homo sapiens
entrez_id 8897
location 22q12.2
transcript_count 3
exon_count 21
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez This gene encodes a member of the myotubularin dual specificity protein phosphatase gene family. The encoded protein is structurally similar to myotubularin but in addition contains a FYVE domain and an N-terminal PH-GRAM domain. The protein can self-associate and also form heteromers with another myotubularin related protein. The protein binds to phosphoinositide lipids through the PH-GRAM domain, and can hydrolyze phosphatidylinositol(3)-phosphate and phosphatidylinositol(3,5)-biphosphate in vitro. The encoded protein has been observed to have a perinuclear, possibly membrane-bound, distribution in cells, but it has also been found free in the cytoplasm. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
    Stringdb Myotubularin-related protein 3; Phosphatase that acts on lipids with a phosphoinositol headgroup. Has phosphatase activity towards phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate. May also dephosphorylate proteins phosphorylated on Ser, Thr, and Tyr residues; Myotubularins
    nextProt Phosphatase that acts on lipids with a phosphoinositol headgroup (PubMed:11676921). Has phosphatase activity towards phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5-bisphosphate (PubMed:11676921). May also dephosphorylate proteins phosphorylated on Ser, Thr, and Tyr residues (PubMed:10733931).
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
MTMR3 BioGRID MTMR9 GeneID BioGRID Negative Genetic
MTMR3 BioGRID MTMR4 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western; Negative Genetic; Proximity Label-MS
MTMR3 BioGRID TOP3B GeneID BioGRID Affinity Capture-RNA
MTMR3 BioGRID TRIM67 GeneID BioGRID Affinity Capture-MS
MTMR3 BioGRID CUL3 GeneID BioGRID Affinity Capture-MS
MTMR3 BioGRID AURKA GeneID BioGRID Affinity Capture-MS
MTMR3 BioGRID YWHAZ GeneID BioGRID Affinity Capture-MS
MTMR3 BioGRID YWHAH GeneID BioGRID Affinity Capture-MS
MTMR3 BioGRID YWHAG GeneID BioGRID Affinity Capture-MS
MTMR3 BioGRID YWHAE GeneID BioGRID Affinity Capture-MS
MTMR3 BioGRID YWHAB GeneID BioGRID Affinity Capture-MS
MTMR3 BioGRID RANGAP1 GeneID BioGRID Affinity Capture-MS
MTMR3 BioGRID NDUFA3 GeneID BioGRID Affinity Capture-MS
MTMR3 BioGRID PNO1 GeneID BioGRID Affinity Capture-MS
MTMR3 BioGRID ABCF3 GeneID BioGRID Affinity Capture-MS
MTMR3 BioGRID MED18 GeneID BioGRID Affinity Capture-MS
MTMR3 BioGRID DNAJC10 GeneID BioGRID Affinity Capture-MS
MTMR3 BioGRID GTSE1 GeneID BioGRID Affinity Capture-MS
MTMR3 BioGRID AIPL1 GeneID BioGRID Affinity Capture-MS
MTMR3 BioGRID HSF2BP GeneID BioGRID Affinity Capture-MS
MTMR3 BioGRID SLU7 GeneID BioGRID Affinity Capture-MS
MTMR3 BioGRID EDEM1 GeneID BioGRID Affinity Capture-MS
MTMR3 BioGRID GTF3C4 GeneID BioGRID Affinity Capture-MS
MTMR3 BioGRID TULP3 GeneID BioGRID Affinity Capture-MS
MTMR3 BioGRID S100A2 GeneID BioGRID Affinity Capture-MS
MTMR3 BioGRID IL10 GeneID BioGRID Affinity Capture-MS
MTMR3 BioGRID CDC25B GeneID BioGRID Affinity Capture-MS
MTMR3 BioGRID ALOX5 GeneID BioGRID Affinity Capture-MS
MTMR3 BioGRID TMEM68 GeneID BioGRID Affinity Capture-MS
MTMR3 BioGRID STN1 GeneID BioGRID Affinity Capture-MS
MTMR3 BioGRID HDAC11 GeneID BioGRID Affinity Capture-MS
MTMR3 BioGRID SYNE3 GeneID BioGRID Proximity Label-MS
MTMR3 BioGRID DERL1 GeneID BioGRID Proximity Label-MS
MTMR3 BioGRID ORF1ab GeneID BioGRID Affinity Capture-MS
MTMR3 BioGRID RHOT2 GeneID BioGRID Proximity Label-MS
MTMR3 BioGRID FIS1 GeneID BioGRID Proximity Label-MS
MTMR3 BioGRID LONRF1 GeneID BioGRID Two-hybrid
MTMR3 BioGRID EXOSC5 GeneID BioGRID Two-hybrid
MTMR3 BioGRID MTMR3 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
MTMR3 BioGRID PLK1 GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
MTMR3 BioGRID CEP55 GeneID BioGRID Affinity Capture-Western
MTMR3 BioGRID VIRMA GeneID BioGRID Affinity Capture-RNA
MTMR3 BioGRID RECQL4 GeneID BioGRID Affinity Capture-MS
MTMR3 BioGRID EGLN3 GeneID BioGRID Affinity Capture-MS
MTMR3 BioGRID TRIM25 GeneID BioGRID Affinity Capture-RNA
MTMR3 BioGRID FGFR2 GeneID BioGRID Two-hybrid
MTMR3 BioGRID MAPK1IP1L GeneID BioGRID Affinity Capture-MS
MTMR3 BioGRID HEATR1 GeneID BioGRID Affinity Capture-MS
MTMR3 BioGRID NUP205 GeneID BioGRID Affinity Capture-MS
MTMR3 BioGRID SSBP1 GeneID BioGRID Affinity Capture-MS
MTMR3 BioGRID ORC4 GeneID BioGRID Affinity Capture-MS
MTMR3 BioGRID IPO5 GeneID BioGRID Affinity Capture-MS
MTMR3 BioGRID EYA3 GeneID BioGRID Affinity Capture-MS
MTMR3 BioGRID Ostm1 GeneID BioGRID Affinity Capture-MS
MTMR3 BioGRID MLST8 GeneID BioGRID Affinity Capture-Western
MTMR3 BioGRID RPTOR GeneID BioGRID Affinity Capture-Western
MTMR3 BioGRID MTOR GeneID BioGRID Affinity Capture-MS; Affinity Capture-Western
MTMR3 BioGRID THOC2 GeneID BioGRID Affinity Capture-MS
MTMR3 BioGRID HERC2 GeneID BioGRID Affinity Capture-MS
MTMR3 BioGRID ATM GeneID BioGRID Affinity Capture-MS
MTMR3 BioGRID WRAP73 GeneID BioGRID Affinity Capture-MS
MTMR3 BioGRID ANKRD28 GeneID BioGRID Proximity Label-MS
MTMR3 BioGRID HIVEP1 GeneID BioGRID Two-hybrid
StringDB
A B experiments database textmining combined score hadb nhadb
MTMR3 SBF2 0 0 459 337 1 1
MTMR3 RAB7B 0 0 181 231 1 1
MTMR3 TRRAP 0 0 0 163 1 1
MTMR3 PIK3C2A 0 650 109 765 1 1
MTMR3 PIP4K2B 0 650 0 668 1 1
MTMR3 DUSP11 0 0 0 191 1 1
MTMR3 ZFYVE1 0 0 466 250 1 2
MTMR3 BOLA2-SMG1P6 0 0 0 172 1 1
MTMR3 RBPJL 0 0 127 234 1 1
MTMR3 NRBF2 0 0 181 181 1 2
MTMR3 ATG2B 0 0 142 209 1 2
MTMR3 MPHOSPH10 0 0 167 482 1 1
MTMR3 STX17 0 0 261 389 1 2
MTMR3 PTPRQ 0 0 171 212 1 1
MTMR3 ATG3 0 0 235 282 1 2
MTMR3 FIBIN 0 0 0 189 1 1
MTMR3 CCDC7 0 0 204 204 1 1
MTMR3 EWSR1 0 0 45 209 1 1
MTMR3 RNPEPL1 0 0 195 375 1 1
MTMR3 EEA1 0 0 218 201 1 2
MTMR3 YWHAB 130 0 0 175 1 1
MTMR3 KLHDC7A 0 0 244 243 1 1
MTMR3 NEK1 0 0 0 243 1 1
MTMR3 SLC2A4 0 0 53 187 1 1
MTMR3 DKC1 0 0 62 157 1 1
MTMR3 GPR112 0 0 180 179 1 1
MTMR3 CEP162 0 0 0 403 1 1
MTMR3 SNX7 0 0 155 205 1 1
MTMR3 GABRR1 0 0 0 227 1 1
MTMR3 AHRR 0 0 122 360 1 1
MTMR3 FBF1 0 0 0 396 1 1
MTMR3 PPM1E 0 0 0 190 1 1
MTMR3 THAP2 0 0 203 507 1 1
MTMR3 ERGIC1 0 0 59 406 1 1
MTMR3 RAB21 0 0 0 187 1 1
MTMR3 PIKFYVE 0 900 622 931 1 2
MTMR3 BRPF3 0 0 166 186 1 1
MTMR3 ATP10B 0 0 0 157 1 1
MTMR3 SSH2 0 0 167 175 1 1
MTMR3 MTMR10 0 0 391 293 1 1
MTMR3 VMP1 0 0 166 256 1 2
MTMR3 MTMR4 460 800 904 918 1 1
MTMR3 ATP10D 0 0 0 157 1 1
MTMR3 AKT1 0 0 171 184 1 2
MTMR3 PPP1R9B 0 0 0 230 1 1
MTMR3 MTMR14 0 0 607 336 1 2
MTMR3 GNL1 0 0 155 154 1 1
MTMR3 SYNJ2 0 0 97 172 1 1
MTMR3 WDTC1 0 0 0 234 1 1
MTMR3 ATP2A3 0 0 0 215 1 1
MTMR3 FAN1 0 0 154 160 1 1
MTMR3 ARL15 0 0 160 189 1 1
MTMR3 DAGLA 0 0 0 158 1 1
MTMR3 WIPI2 0 0 325 370 1 2
MTMR3 IL23R 0 0 140 163 1 1
MTMR3 BTN2A1 0 0 172 171 1 1
MTMR3 ATP11B 0 0 0 157 1 1
MTMR3 PPP1R2 0 0 0 156 1 1
MTMR3 OXTR 0 0 54 262 1 1
MTMR3 NBR1 0 0 126 198 1 2
MTMR3 SMARCD1 0 0 156 239 1 1
MTMR3 CELF1 0 0 118 214 1 1
MTMR3 PLCB1 0 650 0 662 1 1
MTMR3 SACM1L 0 650 258 761 1 1
MTMR3 NUP210 0 0 0 186 1 1
MTMR3 HERC2 270 0 0 278 1 1
MTMR3 GGPS1 0 0 0 188 1 1
MTMR3 MTMR1 0 0 720 181 1 1
MTMR3 PIK3R2 0 650 69 677 1 1
MTMR3 IP6K1 0 0 141 422 1 1
MTMR3 MTMR11 0 0 393 290 1 1
MTMR3 ATP11C 0 0 0 157 1 1
MTMR3 USP19 0 0 0 179 1 1
MTMR3 RAB1B 0 0 107 348 1 2
MTMR3 APOL1 0 0 285 284 1 2
MTMR3 PPP2R2B 0 0 0 205 1 1
MTMR3 UVRAG 0 0 294 359 1 2
MTMR3 ARHGAP9 0 0 97 168 1 1
MTMR3 PIGT 0 0 52 297 1 1
MTMR3 PPP1R14B 0 0 0 207 1 1
MTMR3 ATG4B 0 0 229 363 1 2
MTMR3 PIK3C2G 0 650 95 761 1 1
MTMR3 ATP12A 0 0 0 164 1 1
MTMR3 RAB7A 0 0 182 241 1 2
MTMR3 TMEM55A 0 650 0 658 1 1
MTMR3 DRAM1 0 0 243 242 1 2
MTMR3 FNBP1L 0 0 142 201 1 1
MTMR3 RUFY4 0 0 243 290 1 1
MTMR3 PLEKHA4 0 0 320 544 1 1
MTMR3 ATP2B2 0 0 0 161 1 1
MTMR3 ATR 0 0 0 162 1 2
MTMR3 SNX9 0 0 93 236 1 1
MTMR3 HS6ST2 0 0 125 290 1 1
MTMR3 RCC1 0 0 0 260 1 1
MTMR3 IPPK 0 0 0 189 1 1
MTMR3 GABRR2 0 0 0 207 1 1
MTMR3 DUSP18 0 0 74 156 1 1
MTMR3 PPIP5K2 0 0 163 344 1 1
MTMR3 CFHR3 0 0 242 241 1 1
MTMR3 PRKDC 0 0 0 162 1 2
MTMR3 GLRA1 0 0 0 295 1 1
MTMR3 ERC1 0 0 0 186 1 1
MTMR3 PIK3C2B 0 650 108 764 1 1
MTMR3 OPRM1 0 0 45 297 1 1
MTMR3 ATG2A 0 0 113 157 1 2
MTMR3 CDIPT 0 900 0 917 1 1
MTMR3 ATP11A 0 0 0 157 1 1
MTMR3 APOBR 0 0 165 165 1 1
MTMR3 EXOSC7 192 0 0 192 1 1
MTMR3 TECPR1 0 0 289 333 1 1
MTMR3 PLCE1 0 650 143 694 1 1
MTMR3 ATP2A2 0 0 0 215 1 1
MTMR3 GPR35 0 0 113 174 1 1
MTMR3 REEP4 0 0 208 208 1 1
MTMR3 MDN1 0 0 127 494 1 1
MTMR3 PTPN2 0 0 171 211 1 2
MTMR3 PITPNA 0 0 49 222 1 1
MTMR3 HS6ST3 0 0 0 222 1 1
MTMR3 AMBRA1 0 0 150 260 1 2
MTMR3 PTPRG 0 0 0 219 1 1
MTMR3 GOPC 0 0 0 206 1 2
MTMR3 ANO2 0 0 123 213 1 1
MTMR3 SH3BP1 0 0 0 188 1 1
MTMR3 ATP1A4 0 0 0 164 1 1
MTMR3 PTEN 0 0 164 165 1 2
MTMR3 GABARAP 0 0 119 179 1 2
MTMR3 STXBP5L 0 0 0 153 1 1
MTMR3 GOSR2 0 0 217 217 1 1
MTMR3 KIAA0226 0 0 234 264 1 1
MTMR3 CABP7 0 0 218 218 1 1
MTMR3 EIF3C 0 0 107 171 1 1
MTMR3 PI4KB 0 650 65 702 1 1
MTMR3 WIPI1 0 0 459 473 1 2
MTMR3 RECQL4 270 0 0 270 1 1
MTMR3 RCL1 0 0 134 459 1 1
MTMR3 CLTB 0 0 0 642 1 1
MTMR3 ATP8B3 0 0 0 157 1 1
MTMR3 ATG7 0 0 243 249 1 2
MTMR3 SNX17 0 0 67 160 1 1
MTMR3 DRD5 0 0 86 293 1 1
MTMR3 ATM 151 0 0 150 1 2
MTMR3 TBL3 0 0 172 386 1 1
MTMR3 SLC35E4 0 0 143 377 1 1
MTMR3 ATP8A1 0 0 0 157 1 1
MTMR3 RASL10A 0 0 234 300 1 1
MTMR3 ULK1 0 0 269 290 1 2
MTMR3 PIP4K2C 0 900 0 905 1 1
MTMR3 NUMA1 0 0 90 164 1 1
MTMR3 ATP2B1 0 0 86 312 1 1
MTMR3 PTPRH 0 0 203 286 1 1
MTMR3 MTMR8 0 0 725 450 1 1
MTMR3 PTPRR 0 0 123 181 1 1
MTMR3 MAP1LC3B 0 0 202 208 1 2
MTMR3 EIF2A 0 0 134 188 1 2
MTMR3 AGFG1 0 0 112 159 1 1
MTMR3 CYTH1 0 0 56 155 1 1
MTMR3 CALCOCO2 0 0 210 210 1 2
MTMR3 DUSP21 0 0 90 170 1 1
MTMR3 LAPTM5 0 0 0 188 1 1
MTMR3 KSR1 270 0 0 297 1 1
MTMR3 ATG5 0 0 300 309 1 2
MTMR3 TNFAIP2 0 0 81 339 1 1
MTMR3 PLCD3 0 650 0 684 1 1
MTMR3 ATP4A 0 0 0 164 1 1
MTMR3 PTPRZ1 0 0 91 260 1 1
MTMR3 PLCD1 0 650 0 657 1 1
MTMR3 TP63 0 0 201 201 1 2
MTMR3 C17orf80 0 0 233 232 1 1
MTMR3 INPP4A 0 900 120 910 1 1
MTMR3 CPNE8 0 0 0 228 1 1
MTMR3 TMEM55B 0 650 0 658 1 1
MTMR3 OPTN 0 0 155 154 1 2
MTMR3 LRRK2 0 0 246 291 1 2
MTMR3 PPM1A 0 0 0 151 1 1
MTMR3 CCT8L2 0 0 324 323 1 1
MTMR3 VAC14 0 0 297 297 1 1
MTMR3 PIK3CB 0 0 59 167 1 1
MTMR3 FGD1 0 0 115 208 1 1
MTMR3 MTMR12 0 0 431 316 1 1
MTMR3 USP49 0 0 156 174 1 1
MTMR3 BECN1 0 0 324 339 1 2
MTMR3 DGKE 0 0 134 520 1 1
MTMR3 CTDNEP1 0 0 0 179 1 1
MTMR3 ATP1A1 0 0 0 164 1 1
MTMR3 CDC25A 0 0 92 155 1 1
MTMR3 GABBR1 0 0 0 173 1 1
MTMR3 PPP1R1A 0 0 141 231 1 1
MTMR3 MTMR9 0 0 720 288 1 1
MTMR3 PTPN18 0 0 202 257 1 1
MTMR3 KCNK18 0 0 123 258 1 1
MTMR3 POLR2K 0 0 48 302 1 1
MTMR3 DGKD 0 0 0 259 1 1
MTMR3 MAMLD1 0 0 397 396 1 1
MTMR3 TPTE2 0 0 295 296 1 1
MTMR3 KRAS 0 0 74 152 1 2
MTMR3 MLST8 270 0 108 321 1 1
MTMR3 PDE6A 0 0 108 202 1 1
MTMR3 PLCZ1 0 650 0 650 1 1
MTMR3 PI4K2A 0 650 0 658 1 1
MTMR3 ATP1A2 0 0 0 164 1 1
MTMR3 CAPN10 0 0 324 323 1 2
MTMR3 YWHAH 130 0 0 175 1 1
MTMR3 INPP4B 0 900 134 915 1 1
MTMR3 PIK3CD 0 0 73 179 1 1
MTMR3 CPNE5 0 0 195 414 1 1
MTMR3 ATG16L1 0 0 299 332 1 2
MTMR3 PI4KA 0 650 100 726 1 1
MTMR3 NOD2 0 0 214 214 1 2
MTMR3 PTPRB 0 0 103 164 1 1
MTMR3 KIAA1244 0 0 68 322 1 1
MTMR3 TMEM247 0 0 335 478 1 1
MTMR3 GABRB3 0 0 0 190 1 1
MTMR3 ATG101 0 0 193 193 1 2
MTMR3 PSMG1 0 0 325 325 1 1
MTMR3 NLN 0 0 0 189 1 1
MTMR3 SIPA1L3 0 0 181 181 1 1
MTMR3 PTS 0 0 181 181 1 1
MTMR3 SMARCA1 0 0 0 156 1 1
MTMR3 NEK4 0 0 0 527 1 1
MTMR3 GPR65 0 0 134 157 1 1
MTMR3 ATG12 0 0 279 288 1 2
MTMR3 ALOX5 182 0 0 181 1 1
MTMR3 UTP18 0 0 164 379 1 1
MTMR3 PTPN5 0 0 103 215 1 1
MTMR3 PPM1B 0 0 0 151 1 1
MTMR3 VIPR2 0 0 69 233 1 1
MTMR3 INPP5B 0 0 143 199 1 1
MTMR3 DCAF6 0 0 0 196 1 1
MTMR3 THOP1 0 0 0 189 1 1
MTMR3 PWP2 0 0 155 242 1 1
MTMR3 NOXO1 0 0 57 156 1 1
MTMR3 DOCK1 0 0 0 157 1 1
MTMR3 NDST3 0 0 164 308 1 1
MTMR3 PPP2R2D 0 0 0 156 1 1
MTMR3 ZMAT5 0 0 251 500 1 1
MTMR3 KIAA1429 270 0 0 270 1 1
MTMR3 MTMR6 0 0 730 510 1 1
MTMR3 CHRNA6 0 0 113 309 1 1
MTMR3 RAB5A 0 0 123 153 1 2
MTMR3 EXOSC1 192 0 0 192 1 1
MTMR3 PLEK 0 0 269 269 1 1
MTMR3 RPP25L 0 0 241 486 1 1
MTMR3 MTMR7 0 0 725 622 1 1
MTMR3 TNFRSF19 0 0 261 261 1 1
MTMR3 PIK3C3 0 650 390 828 1 2
MTMR3 PSMC6 0 0 0 190 1 1
MTMR3 MTOR 270 0 234 492 1 2
MTMR3 NKAIN2 0 0 60 168 1 1
MTMR3 GABRB2 0 0 92 233 1 1
MTMR3 PLK1 218 0 456 556 1 2
MTMR3 PPP2R2A 0 0 0 156 1 1
MTMR3 CFHR1 0 0 164 163 1 1
MTMR3 ASCC2 0 0 452 527 1 1
MTMR3 INPPL1 0 0 128 166 1 1
MTMR3 TNFSF13 0 0 260 276 1 1
MTMR3 PLCG2 0 650 61 756 1 1
MTMR3 CLTCL1 0 0 134 671 1 1
MTMR3 BAP1 0 0 82 282 1 1
MTMR3 ATP1A3 0 0 0 164 1 1
MTMR3 FIG4 0 900 160 936 1 1
MTMR3 CREBBP 0 0 0 180 1 1
MTMR3 WDR3 0 0 170 347 1 1
MTMR3 GLRA3 0 0 138 366 1 1
MTMR3 ABL1 0 0 0 220 1 1
MTMR3 ATP8A2 0 0 0 157 1 1
MTMR3 POTEE 0 0 193 193 1 1
MTMR3 SMG1 0 0 0 172 1 1
MTMR3 C1orf106 0 0 181 181 1 1
MTMR3 GABARAPL2 0 0 163 163 1 2
MTMR3 ATG14 0 0 369 377 1 2
MTMR3 PTPN9 0 0 74 216 1 1
MTMR3 UHRF1BP1L 0 0 245 553 1 1
MTMR3 ENSG00000026036 0 0 204 204 1 1
MTMR3 FYCO1 0 0 251 217 1 2
MTMR3 SLC5A4 0 0 0 298 1 1
MTMR3 BNC2 0 0 206 206 1 1
MTMR3 AFF3 0 0 90 162 1 1
MTMR3 ITPR2 0 0 73 394 1 1
MTMR3 PCLO 0 0 82 173 1 1
MTMR3 PHLPP1 0 0 45 150 1 2
MTMR3 PIK3R4 0 0 261 281 1 2
MTMR3 CALCR 0 0 53 187 1 1
MTMR3 PTPLA 0 0 47 293 1 1
MTMR3 GRK7 0 0 0 232 1 1
MTMR3 INPP5F 0 650 72 702 1 1
MTMR3 CLTA 0 0 0 642 1 1
MTMR3 GNAT2 0 0 112 204 1 1
MTMR3 PLCB2 0 650 0 662 1 1
MTMR3 PIK3CA 0 0 0 168 1 2
MTMR3 DHX33 0 0 50 168 1 1
MTMR3 PTPLB 0 0 0 189 1 1
MTMR3 PIK3R3 0 650 0 666 1 1
MTMR3 TNFRSF6B 0 0 435 435 1 1
MTMR3 KIF21B 0 0 134 153 1 1
MTMR3 CDC14A 0 0 180 190 1 1
MTMR3 PI3 0 0 265 265 1 2
MTMR3 PLCB3 0 650 0 667 1 1
MTMR3 PPIP5K1 0 0 0 248 1 1
MTMR3 IRGM 0 0 341 341 1 2
MTMR3 BOLA2 0 0 0 162 1 1
MTMR3 PIP4K2A 0 900 0 903 1 1
MTMR3 SYNJ1 0 0 167 328 1 1
MTMR3 MTMR2 0 0 737 157 1 1
MTMR3 RB1CC1 0 0 261 274 1 2
MTMR3 GOLPH3 0 0 55 171 1 1
MTMR3 STXBP6 0 0 0 222 1 1
MTMR3 SEC16A 0 0 167 167 1 2
MTMR3 RUFY1 0 0 235 166 1 1
MTMR3 B3GNTL1 0 0 108 201 1 1
MTMR3 ATP2C1 0 0 0 215 1 1
MTMR3 HS3ST2 0 0 109 403 1 1
MTMR3 LAMP1 0 0 125 170 1 2
MTMR3 DGKH 0 0 134 331 1 1
MTMR3 SNX12 0 0 123 212 1 1
MTMR3 ATP6V0D1 0 0 123 361 1 1
MTMR3 GSE1 0 0 56 227 1 1
MTMR3 AGO2 0 0 70 213 1 2
MTMR3 INPP5E 0 0 59 169 1 1
MTMR3 NF2 0 0 47 210 1 1
MTMR3 OCRL 0 0 134 172 1 1
MTMR3 CDIP1 0 0 57 161 1 1
MTMR3 MCOLN1 0 0 120 202 1 2
MTMR3 SPINK8 0 0 96 158 1 1
MTMR3 ATP8B4 0 0 0 157 1 1
MTMR3 BAZ2A 0 0 95 309 1 1
MTMR3 ATP2B4 0 0 0 202 1 1
MTMR3 ABHD8 0 0 0 256 1 1
MTMR3 SNX22 0 0 150 200 1 1
MTMR3 GNAT1 0 0 111 203 1 1
MTMR3 CPNE9 0 0 0 228 1 1
MTMR3 PIP5K1C 0 0 74 171 1 1
MTMR3 ARL17A 0 0 189 202 1 1
MTMR3 MADD 0 0 288 305 1 1
MTMR3 ZMIZ1 0 0 310 330 1 1
MTMR3 EXOSC8 192 0 0 192 1 1
MTMR3 TPTE 0 0 325 326 1 1
MTMR3 SH3PXD2B 0 0 0 307 1 1
MTMR3 TBC1D10A 0 0 261 339 1 1
MTMR3 KAT2A 0 0 44 198 1 1
MTMR3 PPM1G 0 0 0 190 1 1
MTMR3 KIF16B 0 0 96 200 1 1
MTMR3 CLPTM1L 0 0 378 378 1 1
MTMR3 PNO1 406 0 0 406 1 1
MTMR3 ATP8B2 0 0 0 157 1 1
MTMR3 ATP2A1 0 0 102 264 1 1
MTMR3 ATP10A 0 0 108 216 1 1
MTMR3 LLGL1 0 0 0 171 1 1
MTMR3 ATG16L2 0 0 242 241 1 2
MTMR3 PLCD4 0 650 166 727 1 1
MTMR3 STK32A 0 0 241 240 1 1
MTMR3 BOLA2B 0 0 0 162 1 1
MTMR3 SH3PXD2A 0 0 0 307 1 1
MTMR3 YWHAG 131 0 0 176 1 1
MTMR3 LOC81691 0 0 0 151 1 1
MTMR3 GABBR2 0 0 70 198 1 1
MTMR3 HLA-DQA1 0 0 155 164 1 1
MTMR3 ATP6V0D2 0 0 0 302 1 1
MTMR3 MIPEP 0 0 385 384 1 1
MTMR3 NISCH 0 0 0 160 1 1
MTMR3 HORMAD2 0 0 631 631 1 1
MTMR3 DYNC2H1 0 0 0 156 1 1
MTMR3 ABL2 0 0 0 220 1 1
MTMR3 FXR1 0 0 145 175 1 1
MTMR3 CECR6 0 0 120 180 1 1
MTMR3 KDM2A 0 0 81 201 1 1
MTMR3 GRM3 0 0 66 320 1 1
MTMR3 PDE6B 0 0 60 159 1 1
MTMR3 ATP2C2 0 0 0 215 1 1
MTMR3 RPTOR 270 0 103 332 1 2
MTMR3 NEK9 0 0 0 152 1 1
MTMR3 EXTL3 0 0 119 360 1 1
MTMR3 RDX 0 0 67 227 1 1
MTMR3 PIK3R1 0 650 81 727 1 1
MTMR3 CLTC 0 0 55 261 1 1
MTMR3 NDST4 0 0 0 207 1 1
MTMR3 SH3GLB1 0 0 233 248 1 2
MTMR3 PTPN3 0 0 124 202 1 1
MTMR3 SMARCA5 0 0 180 340 1 1
MTMR3 PTPRS 0 0 181 203 1 1
MTMR3 TMEM59 0 0 162 182 1 1
MTMR3 PPM1L 0 0 0 368 1 1
MTMR3 DUSP12 0 0 0 207 1 1
MTMR3 MTM1 0 0 812 168 1 2
MTMR3 ATG4A 0 0 207 255 1 2
MTMR3 PIK3CG 0 0 0 151 1 1
MTMR3 STXBP5 0 0 0 153 1 1
MTMR3 ULK2 0 0 143 243 1 2
MTMR3 ARL17B 0 0 180 193 1 1
MTMR3 MED18 182 0 0 181 1 1
MTMR3 ORMDL3 0 0 215 215 1 2
MTMR3 REXO1 0 0 193 498 1 1
MTMR3 PI4K2B 0 650 0 658 1 1
MTMR3 GAS2L1 0 0 185 406 1 1
MTMR3 GAS2L2 0 0 0 187 1 1
MTMR3 DVL3 0 0 0 165 1 1
MTMR3 ZNF165 0 0 194 194 1 1
MTMR3 PLCG1 0 650 74 712 1 1
MTMR3 ASB13 0 0 193 199 1 1
MTMR3 XYLT1 0 0 113 470 1 1
MTMR3 DAPP1 0 0 75 156 1 1
MTMR3 PLCB4 0 650 94 742 1 1
MTMR3 DUSP22 0 0 66 167 1 1
MTMR3 OTUD4 0 0 134 267 1 1
MTMR3 WDFY2 0 0 261 292 1 1
MTMR3 FST 0 0 0 258 1 1
MTMR3 CEP55 120 0 150 220 1 1
MTMR3 RFPL1 0 0 181 181 1 1
MTMR3 GOLGA2 161 0 0 161 1 1
MTMR3 GRN 0 0 0 214 1 1
MTMR3 SNX27 0 0 65 163 1 1
MTMR3 ATP2B3 0 0 0 161 1 1
MTMR3 PPM1F 0 0 0 190 1 1
MTMR3 WDFY1 0 0 274 292 1 1
MTMR3 ERC2 0 0 0 186 1 1
MTMR3 SNX3 0 0 69 167 1 1
MTMR3 XYLT2 0 0 0 157 1 1
MTMR3 AURKA 271 0 0 271 1 2
MTMR3 TULP3 184 0 0 183 1 1
MTMR3 TMEM189 0 0 217 217 1 1
MTMR3 LLGL2 0 0 0 153 1 1
MTMR3 GATSL3 0 0 171 171 1 1
MTMR3 ATG9A 0 0 83 155 1 2
MTMR3 NMD3 0 0 123 315 1 1
MTMR3 GABARAPL1 0 0 180 202 1 2
MTMR3 RAB1A 0 0 44 302 1 1
MTMR3 ENSG00000271810 0 0 0 163 1 1
MTMR3 COBLL1 0 0 234 234 1 1
MTMR3 ZBED5 0 0 305 305 1 1
MTMR3 PHPT1 0 0 142 202 1 1
MTMR3 P2RX2 0 0 67 210 1 1
MTMR3 RHOV 0 0 0 194 1 1
MTMR3 SGPL1 0 0 81 222 1 1
MTMR3 CLEC16A 0 0 180 203 1 2
MTMR3 TFEB 0 0 91 289 1 2
MTMR3 SBF1 0 0 650 422 1 1
MTMR3 ATP8B1 0 0 0 157 1 1
MTMR3 TMEM191B 0 0 153 256 1 1
MTMR3 LRRIQ1 0 0 241 240 1 1
MTMR3 GABRD 0 0 97 343 1 1
MTMR3 ATG13 0 0 247 323 1 2
MTMR3 NEFH 0 0 54 216 1 1
MTMR3 ASH1L 0 0 88 161 1 1
MTMR3 RNGTT 0 0 150 240 1 1
MTMR3 MSN 0 0 0 206 1 1
MTMR3 ENSG00000150076 0 0 204 204 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0046872 Molecular Function metal ion binding enables IEA
GO:0052629 Molecular Function phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity enables IBA
GO:0052629 Molecular Function phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity enables IDA
GO:0052629 Molecular Function phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity enables TAS
GO:0004438 Molecular Function phosphatidylinositol-3-phosphate phosphatase activity enables IBA
GO:0004438 Molecular Function phosphatidylinositol-3-phosphate phosphatase activity enables IDA
GO:0004438 Molecular Function phosphatidylinositol-3-phosphate phosphatase activity enables TAS
GO:0005515 Molecular Function protein binding enables IPI
GO:0019903 Molecular Function protein phosphatase binding enables IBA
GO:0019903 Molecular Function protein phosphatase binding enables IPI
GO:0004722 Molecular Function protein serine/threonine phosphatase activity enables IDA
GO:0004722 Molecular Function protein serine/threonine phosphatase activity enables TAS
GO:0004725 Molecular Function protein tyrosine phosphatase activity enables IDA
GO:0008138 Molecular Function protein tyrosine/serine/threonine phosphatase activity enables IDA
GO:0042149 Biological Process cellular response to glucose starvation involved_in IMP
GO:0016236 Biological Process macroautophagy involved_in TAS
GO:1904562 Biological Process phosphatidylinositol 5-phosphate metabolic process involved_in IDA
GO:0006661 Biological Process phosphatidylinositol biosynthetic process involved_in TAS
GO:0046856 Biological Process phosphatidylinositol dephosphorylation involved_in IBA
GO:0046856 Biological Process phosphatidylinositol dephosphorylation involved_in IDA
GO:0006470 Biological Process protein dephosphorylation involved_in IDA
GO:2000785 Biological Process regulation of autophagosome assembly involved_in IMP
GO:0010506 Biological Process regulation of autophagy involved_in IBA
GO:0060304 Biological Process regulation of phosphatidylinositol dephosphorylation involved_in IDA
GO:0005737 Cellular Component cytoplasm is_active_in IBA
GO:0005737 Cellular Component cytoplasm located_in IDA
GO:0005829 Cellular Component cytosol located_in TAS
GO:0016020 Cellular Component membrane is_active_in IBA
GO:0016020 Cellular Component membrane located_in IDA
Pathways
Name DB ID
Metabolism Reactome R-HSA-1430728
PI Metabolism Reactome R-HSA-1483255
Phospholipid metabolism Reactome R-HSA-1483257
Macroautophagy Reactome R-HSA-1632852
Synthesis of PIPs at the plasma membrane Reactome R-HSA-1660499
Metabolism of lipids Reactome R-HSA-556833
Autophagy Reactome R-HSA-9612973
Phosphoinositides metabolism (WP4971) WikiPathways WP4971_r122106
Transcripts
Accession Version MolecularType Name NCBI Comments
NM_021090 4 mRNA transcript variant 3 NC_000022 Reference
NM_153050 3 mRNA transcript variant 1 NC_000022 Reference
NM_153051 3 mRNA transcript variant 2 NC_000022 Reference