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ORMDL3

ORMDL sphingolipid biosynthesis regulator 3
General Information
Name ORMDL sphingolipid biosynthesis regulator 3
Alias
  • ORM1-like protein 3
Gene_family
organism Homo sapiens
entrez_id 94103
location 17q21.1
transcript_count 7
exon_count 7
Cross References
Location
by NCBI GRCh38.p14
Summary
    Entrez Involved in ceramide metabolic process. Acts upstream of or within several processes, including negative regulation of B cell apoptotic process; negative regulation of ceramide biosynthetic process; and positive regulation of protein localization to nucleus. Located in endoplasmic reticulum. Part of SPOTS complex. [provided by Alliance of Genome Resources, Apr 2022]
    Stringdb ORM1-like protein 3; Negative regulator of sphingolipid synthesis. May indirectly regulate endoplasmic reticulum-mediated Ca(+2) signaling; Belongs to the ORM family
    nextProt Negative regulator of sphingolipid synthesis. May indirectly regulate endoplasmic reticulum-mediated Ca(+2) signaling.
Interactions
NCBI
A A.Source B B.DB B.Source Description PubMed
ORMDL3 BioGRID ZRANB1 GeneID BioGRID Affinity Capture-MS
ORMDL3 BioGRID ORF1ab GeneID BioGRID Proximity Label-MS
ORMDL3 BioGRID PDE2A GeneID BioGRID Affinity Capture-MS
ORMDL3 BioGRID SPTLC1 GeneID BioGRID Affinity Capture-Western
ORMDL3 BioGRID SPRY4 GeneID BioGRID Affinity Capture-MS
ORMDL3 BioGRID ATP13A3 GeneID BioGRID Affinity Capture-MS
ORMDL3 BioGRID CRELD1 GeneID BioGRID Affinity Capture-MS
ORMDL3 BioGRID BSCL2 GeneID BioGRID Affinity Capture-MS
ORMDL3 BioGRID DUSP14 GeneID BioGRID Affinity Capture-MS
ORMDL3 BioGRID SV2A GeneID BioGRID Affinity Capture-MS
ORMDL3 BioGRID SELENBP1 GeneID BioGRID Affinity Capture-MS
ORMDL3 BioGRID SLC5A6 GeneID BioGRID Affinity Capture-MS
ORMDL3 BioGRID TGM3 GeneID BioGRID Affinity Capture-MS
ORMDL3 BioGRID SLC22A4 GeneID BioGRID Affinity Capture-MS
ORMDL3 BioGRID SLC18A2 GeneID BioGRID Affinity Capture-MS
ORMDL3 BioGRID SLC1A1 GeneID BioGRID Affinity Capture-MS
ORMDL3 BioGRID MAGEA8 GeneID BioGRID Affinity Capture-MS
ORMDL3 BioGRID GABBR1 GeneID BioGRID Affinity Capture-MS
ORMDL3 BioGRID CSNK1D GeneID BioGRID Affinity Capture-MS
ORMDL3 BioGRID AQP3 GeneID BioGRID Affinity Capture-MS
ORMDL3 BioGRID WDR5 GeneID BioGRID Affinity Capture-MS
ORMDL3 BioGRID SYVN1 GeneID BioGRID Affinity Capture-Western
ORMDL3 BioGRID HNRNPH1 GeneID BioGRID Affinity Capture-RNA
ORMDL3 BioGRID GPR152 GeneID BioGRID Two-hybrid
ORMDL3 BioGRID HSD17B13 GeneID BioGRID Two-hybrid
ORMDL3 BioGRID C10orf67 GeneID BioGRID Two-hybrid
ORMDL3 BioGRID MTIF3 GeneID BioGRID Two-hybrid
ORMDL3 BioGRID CERS3 GeneID BioGRID Two-hybrid
ORMDL3 BioGRID ARL13B GeneID BioGRID Two-hybrid
ORMDL3 BioGRID FAM209A GeneID BioGRID Two-hybrid
ORMDL3 BioGRID RETREG3 GeneID BioGRID Two-hybrid
ORMDL3 BioGRID SYT2 GeneID BioGRID Two-hybrid
ORMDL3 BioGRID GPR101 GeneID BioGRID Two-hybrid
ORMDL3 BioGRID TMEM237 GeneID BioGRID Two-hybrid
ORMDL3 BioGRID COQ8A GeneID BioGRID Two-hybrid
ORMDL3 BioGRID ERGIC3 GeneID BioGRID Two-hybrid
ORMDL3 BioGRID REEP2 GeneID BioGRID Two-hybrid
ORMDL3 BioGRID SLC35C2 GeneID BioGRID Two-hybrid
ORMDL3 BioGRID LEPROTL1 GeneID BioGRID Two-hybrid
ORMDL3 BioGRID EBP GeneID BioGRID Two-hybrid
ORMDL3 BioGRID KCNK5 GeneID BioGRID Two-hybrid
ORMDL3 BioGRID GET1 GeneID BioGRID Two-hybrid
ORMDL3 BioGRID ELOVL4 GeneID BioGRID Two-hybrid
ORMDL3 BioGRID SLC10A1 GeneID BioGRID Two-hybrid
ORMDL3 BioGRID SLC7A1 GeneID BioGRID Two-hybrid
ORMDL3 BioGRID ROM1 GeneID BioGRID Two-hybrid
ORMDL3 BioGRID RNF5 GeneID BioGRID Two-hybrid
ORMDL3 BioGRID AQP6 GeneID BioGRID Two-hybrid
ORMDL3 BioGRID PTPN11 GeneID BioGRID Two-hybrid
ORMDL3 BioGRID LMNA GeneID BioGRID Two-hybrid
ORMDL3 BioGRID SLC2A12 GeneID BioGRID Affinity Capture-MS
ORMDL3 BioGRID SLC22A9 GeneID BioGRID Affinity Capture-MS
ORMDL3 BioGRID TCTN3 GeneID BioGRID Proximity Label-MS
ORMDL3 BioGRID APP GeneID BioGRID Reconstituted Complex
ORMDL3 BioGRID LNX1 GeneID BioGRID Two-hybrid
ORMDL3 BioGRID ELAVL1 GeneID BioGRID Affinity Capture-RNA
ORMDL3 Protein EEF1A1 GeneID HPRD
ORMDL3 BioGRID EEF1A1 GeneID BioGRID Two-hybrid
StringDB
A B experiments database textmining combined score hadb nhadb
ORMDL3 ALDH3A2 0 0 60 150 1 1
ORMDL3 PDE4D 0 0 595 595 1 1
ORMDL3 FBXL20 0 0 180 179 1 1
ORMDL3 CERS2 0 0 211 388 1 1
ORMDL3 CTRB1 0 0 150 188 1 1
ORMDL3 RERG 0 0 108 244 1 1
ORMDL3 STK32A 0 0 0 240 1 1
ORMDL3 ZNF365 0 0 261 261 1 1
ORMDL3 MAF 0 0 235 235 1 1
ORMDL3 FAM167A 0 0 310 309 1 1
ORMDL3 BSG 0 0 0 190 1 1
ORMDL3 DEGS1 0 0 181 262 1 1
ORMDL3 CPTP 0 0 95 197 1 1
ORMDL3 ATP8B2 0 0 0 165 1 1
ORMDL3 ATP10A 0 0 0 165 1 1
ORMDL3 ATP2A1 0 0 436 541 1 1
ORMDL3 SPNS2 0 0 185 266 1 1
ORMDL3 ZNF707 0 0 212 224 1 1
ORMDL3 PGAP3 0 0 561 663 1 1
ORMDL3 OSBPL2 0 0 0 208 1 1
ORMDL3 SGK2 0 0 0 262 1 1
ORMDL3 CLPTM1L 0 0 69 191 1 1
ORMDL3 CLEC3A 0 0 134 291 1 1
ORMDL3 PHF11 0 0 424 428 1 1
ORMDL3 TMEM180 0 0 180 179 1 1
ORMDL3 AOAH 0 0 150 216 1 1
ORMDL3 ITLN1 0 0 155 177 1 1
ORMDL3 IL9 0 0 165 165 1 1
ORMDL3 ANKRD55 0 0 229 257 1 1
ORMDL3 IL4 0 0 369 369 1 1
ORMDL3 ENSG00000267318 0 0 0 240 1 1
ORMDL3 DDC 0 0 0 176 1 1
ORMDL3 IL17REL 0 0 233 232 1 1
ORMDL3 ZMIZ1 0 0 218 218 1 1
ORMDL3 PPEF1 0 0 71 150 1 1
ORMDL3 CTNNA3 0 0 217 217 1 1
ORMDL3 PIP5K1C 0 0 0 151 1 1
ORMDL3 SLC2A13 0 0 0 188 1 1
ORMDL3 SMAD3 0 0 464 463 1 2
ORMDL3 PPAPDC1B 0 0 0 171 1 1
ORMDL3 ELOVL1 0 0 45 164 1 1
ORMDL3 WDR36 0 0 505 505 1 1
ORMDL3 PYHIN1 0 0 563 563 1 1
ORMDL3 AGMO 0 0 0 150 1 1
ORMDL3 KIAA0391 0 0 154 153 1 1
ORMDL3 IGSF8 0 0 95 182 1 1
ORMDL3 GPAT2 0 0 90 338 1 1
ORMDL3 IL17A 0 0 170 169 1 2
ORMDL3 SPTSSA 0 900 401 952 1 1
ORMDL3 CRHR1 0 0 210 210 1 1
ORMDL3 IL12RB2 0 0 233 232 1 1
ORMDL3 ATP2C2 0 0 85 255 1 1
ORMDL3 IFIH1 0 0 210 224 1 1
ORMDL3 LRRC19 0 0 152 186 1 1
ORMDL3 ARHGEF3 0 0 0 151 1 1
ORMDL3 TMEM211 0 0 203 241 1 1
ORMDL3 SSFA2 0 0 123 247 1 1
ORMDL3 CSAD 0 0 0 176 1 1
ORMDL3 GSDMB 0 0 872 910 1 1
ORMDL3 TUFM 0 0 96 360 1 2
ORMDL3 BVES 0 0 158 157 1 1
ORMDL3 PTGER4 0 0 218 423 1 1
ORMDL3 GPD1L 0 0 64 156 1 1
ORMDL3 CD244 0 0 0 303 1 1
ORMDL3 PRNP 0 0 193 193 1 2
ORMDL3 HNMT 0 0 499 499 1 1
ORMDL3 GRINA 0 0 0 158 1 1
ORMDL3 FLG 0 0 425 424 1 1
ORMDL3 SEC14L3 0 0 138 206 1 1
ORMDL3 RPS6KB2 0 0 0 262 1 2
ORMDL3 GRB7 0 0 262 310 1 1
ORMDL3 KCNS3 0 0 291 290 1 1
ORMDL3 TBXA2R 0 0 194 246 1 1
ORMDL3 C5orf56 0 0 162 161 1 1
ORMDL3 HLA-DQA1 0 0 253 252 1 1
ORMDL3 ADAM8 0 0 310 324 1 1
ORMDL3 LRRC32 0 0 458 470 1 1
ORMDL3 KRTAP4-11 0 0 156 155 1 1
ORMDL3 LTC4S 0 0 377 381 1 1
ORMDL3 CAMK1D 0 0 48 172 1 1
ORMDL3 PNCK 0 0 0 166 1 1
ORMDL3 ORM2 0 0 814 849 1 1
ORMDL3 RUNX3 0 0 167 167 1 1
ORMDL3 ENSG00000270024 0 0 0 262 1 1
ORMDL3 PLA2G15 0 0 0 244 1 1
ORMDL3 SPATS2L 0 0 194 194 1 1
ORMDL3 AGPAT1 0 0 72 323 1 1
ORMDL3 TLE4 0 0 271 271 1 1
ORMDL3 RTN1 0 0 72 204 1 1
ORMDL3 CYSLTR1 0 0 235 235 1 1
ORMDL3 GOLPH3L 0 0 163 163 1 1
ORMDL3 NCK2 0 0 60 179 1 1
ORMDL3 ERN2 0 0 336 429 1 1
ORMDL3 LAMB1 0 0 193 193 1 1
ORMDL3 ELOVL6 0 0 0 224 1 1
ORMDL3 ENSG00000173366 0 0 137 219 1 1
ORMDL3 LYRM9 0 0 203 203 1 1
ORMDL3 SEPSECS 0 0 0 176 1 1
ORMDL3 SERPINB2 0 0 67 162 1 1
ORMDL3 TYK2 0 0 186 222 1 1
ORMDL3 TM6SF1 0 0 123 213 1 1
ORMDL3 ADTRP 0 0 0 228 1 1
ORMDL3 SEZ6L 0 0 94 232 1 1
ORMDL3 CHEK1 0 0 0 211 1 2
ORMDL3 GHDC 0 0 166 178 1 1
ORMDL3 SPTLC3 0 900 290 959 1 1
ORMDL3 HLA-DRB1 0 0 260 260 1 1
ORMDL3 ELOVL4 75 0 0 245 1 1
ORMDL3 SERINC3 0 0 91 173 1 1
ORMDL3 CERS5 0 0 146 324 1 1
ORMDL3 C1orf186 0 0 194 194 1 1
ORMDL3 CERKL 0 0 0 410 1 1
ORMDL3 AK2 0 0 74 165 1 1
ORMDL3 KCNT1 0 0 90 171 1 1
ORMDL3 MSMO1 0 0 54 280 1 1
ORMDL3 ORM1 0 0 769 813 1 1
ORMDL3 SARAF 0 0 360 511 1 1
ORMDL3 PTGDR 0 0 398 398 1 1
ORMDL3 ZNF804A 0 0 92 438 1 1
ORMDL3 IL3 0 0 95 157 1 1
ORMDL3 ATP8B1 0 0 0 165 1 1
ORMDL3 SP100 0 0 90 247 1 1
ORMDL3 UGCG 0 0 170 253 1 1
ORMDL3 CLEC16A 0 0 451 453 1 2
ORMDL3 SGPL1 0 0 209 468 1 1
ORMDL3 TMEM129 0 0 0 173 1 1
ORMDL3 ADAD1 0 0 170 169 1 1
ORMDL3 NPSR1 0 0 536 567 1 1
ORMDL3 SGMS1 0 0 122 210 1 1
ORMDL3 LY9 0 0 0 250 1 1
ORMDL3 CPEB4 0 0 204 204 1 1
ORMDL3 HNRNPH1 270 0 0 270 1 1
ORMDL3 ZPBP2 0 0 827 828 1 1
ORMDL3 UBE2L3 0 0 169 169 1 1
ORMDL3 GNA12 0 0 315 351 1 1
ORMDL3 KIAA1109 0 0 261 274 1 1
ORMDL3 ARHGAP33 0 0 134 155 1 1
ORMDL3 SPNS1 0 0 137 175 1 2
ORMDL3 TRAPPC8 0 0 0 175 1 1
ORMDL3 HLA-G 0 0 193 193 1 1
ORMDL3 SORT1 0 0 90 249 1 1
ORMDL3 MTMR3 0 0 215 215 1 2
ORMDL3 GOLGA7B 0 540 293 660 1 1
ORMDL3 SPINK5 0 0 321 321 1 1
ORMDL3 GLA 0 0 261 261 1 2
ORMDL3 IL6 0 0 223 223 1 2
ORMDL3 MPO 0 0 0 206 1 2
ORMDL3 B4GALNT3 0 0 125 212 1 1
ORMDL3 KCNMA1 0 0 47 213 1 1
ORMDL3 THRA 0 0 181 225 1 1
ORMDL3 KCNJ9 0 0 51 201 1 1
ORMDL3 COG6 0 0 108 168 1 1
ORMDL3 IL1B 0 0 166 165 1 2
ORMDL3 GLT1D1 0 0 62 205 1 1
ORMDL3 CACNG3 0 0 0 190 1 1
ORMDL3 PKD1L1 0 0 108 170 1 1
ORMDL3 POSTN 0 0 184 202 1 1
ORMDL3 IL6R 0 0 284 284 1 1
ORMDL3 OTUD3 0 0 182 181 1 1
ORMDL3 ZNF619 0 0 265 276 1 1
ORMDL3 CXCL8 0 0 190 190 1 2
ORMDL3 DDOST 0 0 0 212 1 1
ORMDL3 FCRL3 0 0 236 236 1 1
ORMDL3 S1PR3 0 0 141 180 1 1
ORMDL3 SLC35G1 0 0 123 258 1 1
ORMDL3 DNM3 0 0 0 170 1 1
ORMDL3 B7RP1 0 0 194 194 1 1
ORMDL3 SP140L 0 0 0 483 1 1
ORMDL3 SH2B2 0 0 0 171 1 1
ORMDL3 LACC1 0 0 248 248 1 1
ORMDL3 PASK 0 0 0 156 1 1
ORMDL3 DHCR7 0 0 45 198 1 1
ORMDL3 PLA2G4A 0 0 142 174 1 1
ORMDL3 ABTB2 0 0 150 280 1 1
ORMDL3 STAT4 0 0 234 234 1 1
ORMDL3 NPTN 0 0 66 582 1 1
ORMDL3 INTS12 0 0 180 179 1 1
ORMDL3 TPO 0 0 45 305 1 1
ORMDL3 GLCCI1 0 0 422 422 1 1
ORMDL3 LONRF2 0 0 157 190 1 1
ORMDL3 CACNA1G 0 0 0 157 1 1
ORMDL3 RORA 0 0 403 403 1 1
ORMDL3 PSRC1 0 0 124 508 1 1
ORMDL3 ELOVL5 0 0 44 193 1 1
ORMDL3 LRRC3C 0 0 561 664 1 1
ORMDL3 TNFRSF25 0 0 170 169 1 1
ORMDL3 SVOPL 0 0 125 215 1 1
ORMDL3 SH2B3 0 0 262 262 1 1
ORMDL3 SLC22A13 0 0 0 189 1 1
ORMDL3 TMBIM4 0 0 0 155 1 1
ORMDL3 TLR4 0 0 150 169 1 2
ORMDL3 ATP8A2 0 0 0 165 1 1
ORMDL3 MANEA 0 0 142 198 1 1
ORMDL3 TNFSF15 0 0 325 325 1 1
ORMDL3 CYSLTR2 0 0 288 288 1 1
ORMDL3 RAD50 0 0 287 286 1 1
ORMDL3 FIG4 0 0 0 217 1 1
ORMDL3 HLA-DPB1 0 0 264 264 1 1
ORMDL3 HAVCR1 0 0 86 182 1 1
ORMDL3 SLC22A4 0 0 212 420 1 1
ORMDL3 NOTCH4 0 0 202 202 1 1
ORMDL3 ELOVL2 0 0 0 244 1 1
ORMDL3 GSDMD 0 0 155 165 1 2
ORMDL3 CCL5 0 0 151 150 1 2
ORMDL3 CRACR2A 0 0 218 241 1 1
ORMDL3 HLA-DQA2 0 0 261 261 1 1
ORMDL3 IL2RB 0 0 492 491 1 1
ORMDL3 IFNG 0 0 150 173 1 2
ORMDL3 EFHD1 0 0 95 186 1 1
ORMDL3 ATP13A1 0 0 0 164 1 1
ORMDL3 TNFSF13 0 0 91 163 1 1
ORMDL3 PLA2G2E 0 0 181 181 1 1
ORMDL3 PDE11A 0 0 213 244 1 1
ORMDL3 FAM129A 0 0 82 174 1 1
ORMDL3 NUS1 0 0 0 246 1 1
ORMDL3 SYNGR1 0 0 193 193 1 1
ORMDL3 PPAPDC1A 0 0 0 171 1 1
ORMDL3 FAM13A 0 0 244 243 1 1
ORMDL3 IL4R 0 0 341 341 1 1
ORMDL3 SC5D 0 0 0 159 1 1
ORMDL3 OSBPL1A 0 0 108 326 1 1
ORMDL3 GSDMA 0 0 710 726 1 1
ORMDL3 SYNGR2 0 0 95 220 1 1
ORMDL3 S1PR2 0 0 217 238 1 1
ORMDL3 ZPBP 0 0 285 284 1 1
ORMDL3 SAMD8 0 0 91 211 1 1
ORMDL3 ACSL1 0 0 48 219 1 1
ORMDL3 CHI3L1 0 0 435 438 1 1
ORMDL3 METTL21B 0 0 240 239 1 1
ORMDL3 ACER3 0 0 57 213 1 1
ORMDL3 MAP2K5 0 0 43 166 1 1
ORMDL3 BACH2 0 0 325 325 1 1
ORMDL3 CH25H 0 0 0 195 1 1
ORMDL3 B4GALNT1 0 0 89 233 1 1
ORMDL3 TNPO3 0 0 261 261 1 1
ORMDL3 RTN2 0 0 0 185 1 1
ORMDL3 IKZF3 0 0 681 732 1 1
ORMDL3 USP38 0 0 424 424 1 1
ORMDL3 SYNJ1 0 0 0 263 1 1
ORMDL3 RPS26 0 0 150 497 1 1
ORMDL3 C5orf30 0 0 290 290 1 1
ORMDL3 IRGM 0 0 469 502 1 2
ORMDL3 STK32B 0 0 0 240 1 1
ORMDL3 PLCL1 0 0 189 189 1 1
ORMDL3 STIMATE-MUSTN1 0 0 260 587 1 1
ORMDL3 KIF21B 0 0 218 218 1 1
ORMDL3 TAGAP 0 0 181 181 1 1
ORMDL3 FA2H 0 0 0 227 1 1
ORMDL3 GSTCD 0 0 158 157 1 1
ORMDL3 P4HB 0 0 151 242 1 2
ORMDL3 SLC7A1 129 0 0 165 1 1
ORMDL3 HHIP 0 0 194 194 1 1
ORMDL3 INPP5F 0 0 0 217 1 1
ORMDL3 IL2RA 0 0 241 240 1 1
ORMDL3 SBNO2 0 0 155 263 1 1
ORMDL3 ZBTB10 0 0 248 259 1 1
ORMDL3 CHRNA3 0 0 134 157 1 1
ORMDL3 FCER2 0 0 341 341 1 1
ORMDL3 HLA-DQB1 0 0 406 406 1 1
ORMDL3 PLEKHA8 0 0 171 171 1 1
ORMDL3 JAK2 0 0 217 251 1 2
ORMDL3 ANKRD42 0 0 211 240 1 1
ORMDL3 AGR2 0 0 464 497 1 1
ORMDL3 ATP8B4 0 0 0 165 1 1
ORMDL3 FLRT1 0 0 103 184 1 1
ORMDL3 CTBP2 0 0 0 161 1 1
ORMDL3 SLC22A3 0 0 0 189 1 1
ORMDL3 MUC5AC 0 0 193 224 1 1
ORMDL3 GATA3 0 0 246 264 1 1
ORMDL3 NAALAD2 0 0 184 208 1 1
ORMDL3 SFT2D2 0 0 0 160 1 1
ORMDL3 SPTLC1 270 900 551 987 1 1
ORMDL3 ERN1 0 0 282 376 1 2
ORMDL3 MRPL53 0 0 141 165 1 1
ORMDL3 STAT3 0 0 184 183 1 2
ORMDL3 PTPN22 0 0 405 405 1 1
ORMDL3 GCAT 0 0 0 331 1 1
ORMDL3 CFTR 0 0 74 178 1 2
ORMDL3 ATP2C1 0 0 0 220 1 1
ORMDL3 TSLP 0 0 556 556 1 1
ORMDL3 LACTB 0 0 134 209 1 1
ORMDL3 GRAMD1C 0 0 244 262 1 1
ORMDL3 CCDC38 0 0 164 326 1 1
ORMDL3 CARD9 0 0 267 267 1 1
ORMDL3 MUC5B 0 0 181 213 1 1
ORMDL3 CSF3 0 0 96 192 1 1
ORMDL3 SFT2D1 0 0 0 160 1 1
ORMDL3 ADAM33 0 0 681 681 1 1
ORMDL3 ORAI1 0 0 122 186 1 1
ORMDL3 TMEM39A 0 0 265 265 1 1
ORMDL3 LRRC8B 0 0 118 256 1 1
ORMDL3 C10orf67 111 0 65 154 1 1
ORMDL3 LCAT 0 0 0 203 1 1
ORMDL3 IL18RAP 0 0 246 250 1 1
ORMDL3 GAD2 0 0 45 179 1 1
ORMDL3 COL4A3BP 0 0 107 162 1 1
ORMDL3 S1PR5 0 0 123 163 1 1
ORMDL3 GCNT7 0 0 156 173 1 1
ORMDL3 AIF1L 0 0 140 188 1 1
ORMDL3 UBASH3A 0 0 325 325 1 1
ORMDL3 PPP3R1 0 0 0 153 1 1
ORMDL3 MS4A2 0 0 324 323 1 1
ORMDL3 IL10 0 0 283 282 1 2
ORMDL3 IKZF1 0 0 216 228 1 1
ORMDL3 FAIM2 0 0 91 356 1 1
ORMDL3 SKAP2 0 0 263 263 1 1
ORMDL3 ATP8B3 0 0 124 220 1 1
ORMDL3 STOML3 0 0 123 195 1 1
ORMDL3 PRKAA2 0 0 64 499 1 2
ORMDL3 CERK 0 0 195 299 1 1
ORMDL3 SLC22A2 0 0 0 189 1 1
ORMDL3 MBP 0 0 0 303 1 2
ORMDL3 GSDMC 0 0 217 217 1 1
ORMDL3 FDXACB1 0 0 294 294 1 1
ORMDL3 LTA4H 0 0 194 218 1 1
ORMDL3 MMEL1 0 0 403 403 1 1
ORMDL3 STK40 0 0 60 163 1 1
ORMDL3 CD226 0 0 145 193 1 1
ORMDL3 ENSG00000273398 0 0 0 153 1 1
ORMDL3 ORMDL2 0 540 830 547 1 1
ORMDL3 EFHD2 0 0 0 163 1 1
ORMDL3 BTNL2 0 0 118 166 1 1
ORMDL3 IRF5 0 0 276 276 1 1
ORMDL3 DUOX2 0 0 66 320 1 1
ORMDL3 PCDH1 0 0 455 466 1 1
ORMDL3 CELSR1 0 0 0 225 1 1
ORMDL3 IP6K2 0 0 95 163 1 1
ORMDL3 DLK1 0 0 0 214 1 1
ORMDL3 OVOL1 0 0 165 165 1 1
ORMDL3 NKX2-3 0 0 420 427 1 2
ORMDL3 TSPYL5 0 0 90 182 1 1
ORMDL3 ACADS 0 0 74 157 1 1
ORMDL3 SLC22A5 0 0 452 631 1 1
ORMDL3 PRKAG2 0 0 81 176 1 1
ORMDL3 HLA-C 0 0 170 190 1 1
ORMDL3 APOA5 0 0 45 215 1 1
ORMDL3 XBP1 0 0 460 471 1 2
ORMDL3 TSPAN32 0 0 218 218 1 1
ORMDL3 CAMK1 0 0 0 166 1 1
ORMDL3 HYDIN 0 0 96 197 1 1
ORMDL3 CNGA4 0 0 107 162 1 1
ORMDL3 SPHK1 0 0 278 405 1 2
ORMDL3 SPHK2 0 0 246 379 1 1
ORMDL3 APBB3 0 0 0 286 1 1
ORMDL3 AGPAT4 0 0 96 396 1 1
ORMDL3 EPX 0 0 91 390 1 1
ORMDL3 PHLDB1 0 0 97 238 1 1
ORMDL3 RNLS 0 0 375 375 1 1
ORMDL3 PPP1R14A 0 0 54 153 1 1
ORMDL3 TBX21 0 0 207 207 1 1
ORMDL3 ATP8A1 0 0 0 165 1 1
ORMDL3 CERS3 115 0 49 303 1 1
ORMDL3 ANKEF1 0 0 172 207 1 1
ORMDL3 CAMK4 0 0 0 166 1 1
ORMDL3 HSPA5 0 0 167 208 1 2
ORMDL3 ROM1 153 0 0 152 1 1
ORMDL3 HLA-B 0 0 180 200 1 1
ORMDL3 LRRC43 0 0 262 278 1 1
ORMDL3 SH2B1 0 0 55 313 1 1
ORMDL3 CTRB2 0 0 122 162 1 1
ORMDL3 SLC25A46 0 0 134 193 1 1
ORMDL3 PSORS1C1 0 0 202 202 1 1
ORMDL3 TNIP1 0 0 211 231 1 1
ORMDL3 IRAK3 0 0 430 455 1 1
ORMDL3 PTPN11 192 0 0 220 1 1
ORMDL3 AGPAT6 0 0 67 226 1 1
ORMDL3 FCER1A 0 0 284 284 1 1
ORMDL3 WIPF2 0 0 141 157 1 1
ORMDL3 OSBPL11 0 0 0 194 1 1
ORMDL3 RTP1 0 0 113 180 1 1
ORMDL3 PAK4 0 0 46 165 1 1
ORMDL3 ENSG00000277117 0 0 194 194 1 1
ORMDL3 IL18R1 0 0 653 653 1 1
ORMDL3 PDIA3 0 0 68 188 1 1
ORMDL3 HLA-DRA 0 0 241 240 1 1
ORMDL3 NOD1 0 0 142 158 1 2
ORMDL3 GLIS3 0 0 247 258 1 1
ORMDL3 APBA2 0 0 0 221 1 1
ORMDL3 KCNMB3 0 0 108 172 1 1
ORMDL3 ORMDL1 0 540 830 557 1 1
ORMDL3 TMEM110 0 0 260 602 1 1
ORMDL3 IL2 0 0 176 175 1 1
ORMDL3 HLA-DPA1 0 0 204 204 1 1
ORMDL3 FRRS1L 0 0 113 268 1 1
ORMDL3 BECN1 0 0 124 176 1 2
ORMDL3 MAPT 0 0 46 151 1 2
ORMDL3 SGPP1 0 0 202 364 1 1
ORMDL3 SLC22A9 179 0 0 184 1 1
ORMDL3 LRRK2 0 0 261 296 1 2
ORMDL3 TLR2 0 0 124 172 1 2
ORMDL3 CERS6 0 0 187 369 1 1
ORMDL3 DUSP1 0 0 114 169 1 1
ORMDL3 ENSG00000279316 0 0 254 254 1 1
ORMDL3 IL13 0 0 505 505 1 2
ORMDL3 TMEM56 0 0 166 165 1 1
ORMDL3 ALOX5 0 0 247 246 1 1
ORMDL3 BTN1A1 0 0 71 165 1 1
ORMDL3 PRR5L 0 0 216 216 1 1
ORMDL3 MIEN1 0 0 325 428 1 1
ORMDL3 LNX1 192 0 74 219 1 1
ORMDL3 REL 0 0 144 163 1 2
ORMDL3 TMEM208 0 0 0 171 1 1
ORMDL3 PLA2G7 0 0 291 290 1 1
ORMDL3 IL33 0 0 601 601 1 2
ORMDL3 TRIB3 0 0 45 166 1 2
ORMDL3 DEXI 0 0 284 310 1 1
ORMDL3 PDE4DIP 0 0 123 154 1 1
ORMDL3 DDX6 0 0 71 190 1 1
ORMDL3 CCL11 0 0 214 214 1 1
ORMDL3 CNKSR3 0 0 156 155 1 1
ORMDL3 KCNH4 0 0 98 153 1 1
ORMDL3 IL1RL1 0 0 681 681 1 1
ORMDL3 ATG16L1 0 0 459 462 1 2
ORMDL3 SGMS2 0 0 113 282 1 1
ORMDL3 CELSR2 0 0 122 361 1 1
ORMDL3 GPR126 0 0 108 202 1 1
ORMDL3 NOD2 0 0 393 394 1 2
ORMDL3 TMEM106B 0 0 75 188 1 1
ORMDL3 PTGES3 0 0 0 152 1 1
ORMDL3 PRDM1 0 0 147 169 1 1
ORMDL3 PSMD3 0 0 421 454 1 1
ORMDL3 BLK 0 0 233 496 1 1
ORMDL3 ACTL9 0 0 294 316 1 1
ORMDL3 PPP6C 0 0 0 232 1 1
ORMDL3 KRT222 0 0 241 240 1 1
ORMDL3 JAZF1 0 0 219 302 1 1
ORMDL3 AGPAT2 0 0 0 211 1 1
ORMDL3 FBXL7 0 0 216 233 1 1
ORMDL3 APBB2 0 0 0 202 1 1
ORMDL3 EED 0 0 0 167 1 1
ORMDL3 TMEM232 0 0 245 245 1 1
ORMDL3 ADRA1B 0 0 310 309 1 1
ORMDL3 PDZD8 0 0 134 332 1 1
ORMDL3 RTN3 0 0 0 185 1 1
ORMDL3 GAD1 0 0 0 176 1 1
ORMDL3 STAT6 0 0 391 390 1 1
ORMDL3 ALAS2 0 0 0 331 1 1
ORMDL3 SLC30A8 0 0 160 178 1 1
ORMDL3 OCIAD1 0 0 0 181 1 1
ORMDL3 SUOX 0 0 181 181 1 1
ORMDL3 CDHR3 0 0 607 634 1 1
ORMDL3 MFAP3L 0 0 129 248 1 1
ORMDL3 NDFIP1 0 0 323 335 1 1
ORMDL3 CAMK1G 0 0 0 166 1 1
ORMDL3 CTCF 0 0 359 369 1 1
ORMDL3 PPIL3 0 0 147 165 1 1
ORMDL3 DHCR24 0 0 60 163 1 1
ORMDL3 PIGO 0 0 0 150 1 1
ORMDL3 SCGB1A1 0 0 204 204 1 1
ORMDL3 GHITM 0 0 95 268 1 1
ORMDL3 TAF5L 0 0 113 193 1 1
ORMDL3 TGFB1 0 0 181 181 1 2
ORMDL3 POPDC3 0 0 134 152 1 1
ORMDL3 CDKAL1 0 0 134 271 1 1
ORMDL3 SYNJ2 0 0 0 263 1 1
ORMDL3 SGK3 0 0 0 262 1 1
ORMDL3 CD4 0 0 272 272 1 2
ORMDL3 ATP2A3 0 0 119 283 1 1
ORMDL3 MBTPS1 0 0 174 207 1 1
ORMDL3 DOLPP1 0 0 0 150 1 1
ORMDL3 ATP10D 0 0 0 165 1 1
ORMDL3 SPIB 0 0 208 208 1 1
ORMDL3 CD48 0 0 202 259 1 1
ORMDL3 ACKR1 0 0 142 189 1 1
ORMDL3 SP140 0 0 167 505 1 1
ORMDL3 IL12RB1 0 0 150 209 1 1
ORMDL3 KDSR 0 0 181 452 1 1
ORMDL3 SLC2A12 179 0 0 198 1 1
ORMDL3 CRISPLD2 0 0 155 154 1 1
ORMDL3 ATP10B 0 0 0 165 1 1
ORMDL3 CACNG8 0 0 0 250 1 1
ORMDL3 SCGB2A1 0 0 290 290 1 1
ORMDL3 DCTN5 0 0 44 209 1 1
ORMDL3 AMZ2 0 0 154 153 1 1
ORMDL3 DUOX1 0 0 74 242 1 1
ORMDL3 GSTM1 0 0 201 205 1 1
ORMDL3 ATF6 0 0 290 331 1 2
ORMDL3 ENSG00000279392 0 0 169 169 1 1
ORMDL3 UMODL1 0 0 144 234 1 1
ORMDL3 ALAS1 0 0 0 331 1 1
ORMDL3 RTN4 0 0 54 189 1 1
ORMDL3 RTP2 0 0 167 252 1 1
ORMDL3 ZNF652 0 0 181 195 1 1
ORMDL3 CERS4 0 0 0 241 1 1
ORMDL3 PUS10 0 0 194 194 1 1
ORMDL3 HMGA2 0 0 0 181 1 1
ORMDL3 BCO1 0 0 95 160 1 1
ORMDL3 MED24 0 0 108 214 1 1
ORMDL3 ARG2 0 0 202 202 1 1
ORMDL3 ERBB2 0 0 181 295 1 2
ORMDL3 CASC3 0 0 189 226 1 1
ORMDL3 MRPL9 0 0 165 165 1 1
ORMDL3 GOSR1 0 0 0 171 1 1
ORMDL3 CLCA1 0 0 181 181 1 1
ORMDL3 CREM 0 0 146 181 1 1
ORMDL3 TLR9 0 0 135 217 1 2
ORMDL3 C1QTNF6 0 0 244 243 1 1
ORMDL3 SLAMF9 0 0 0 250 1 1
ORMDL3 OR2W3 0 0 180 179 1 1
ORMDL3 CACNG2 0 0 0 189 1 1
ORMDL3 SPTSSB 0 900 324 945 1 1
ORMDL3 IL5 0 0 324 323 1 1
ORMDL3 TNFAIP3 0 0 166 165 1 2
ORMDL3 FAM169B 0 0 181 181 1 1
ORMDL3 ERAP2 0 0 279 279 1 1
ORMDL3 GSTP1 0 0 216 216 1 1
ORMDL3 CST1 0 0 210 221 1 1
ORMDL3 LIPG 0 0 49 194 1 1
ORMDL3 MSLNL 0 0 202 251 1 1
ORMDL3 APBA1 0 0 0 325 1 1
ORMDL3 ELOVL7 0 0 0 160 1 1
ORMDL3 CHIA 0 0 230 257 1 1
ORMDL3 HDC 0 0 0 176 1 1
ORMDL3 STK32C 0 0 0 240 1 1
ORMDL3 TMEM182 0 0 157 156 1 1
ORMDL3 CDK12 0 0 282 308 1 1
ORMDL3 TNF 0 0 234 234 1 2
ORMDL3 DPP10 0 0 602 602 1 1
ORMDL3 SACM1L 0 0 134 518 1 1
ORMDL3 FAXDC2 0 0 0 195 1 1
ORMDL3 IL23R 0 0 394 401 1 1
ORMDL3 IKZF4 0 0 342 352 1 1
ORMDL3 C11orf30 0 0 556 556 1 1
ORMDL3 SMPD2 0 0 95 366 1 1
ORMDL3 GOLGA7 0 900 0 902 1 1
ORMDL3 C15orf32 0 0 254 254 1 1
ORMDL3 SLC22A7 0 0 0 189 1 1
ORMDL3 AIG1 0 0 0 228 1 1
ORMDL3 ZDHHC9 0 900 93 907 1 1
ORMDL3 PCDHB1 0 0 136 202 1 1
ORMDL3 RNASEL 0 0 48 163 1 1
ORMDL3 NR1D1 0 0 143 159 1 2
ORMDL3 PTPN2 0 0 337 345 1 2
ORMDL3 GPAM 0 0 92 228 1 1
ORMDL3 PTPLAD2 0 0 117 159 1 1
ORMDL3 APOBR 0 0 139 157 1 1
ORMDL3 ATP2A2 0 0 76 287 1 1
ORMDL3 CAPN14 0 0 230 229 1 1
ORMDL3 CTLA4 0 0 216 216 1 2
ORMDL3 PDPK1 0 0 0 261 1 2
ORMDL3 SGPP2 0 0 143 351 1 1
ORMDL3 COL6A5 0 0 167 167 1 1
ORMDL3 AGPAT3 0 0 0 200 1 1
ORMDL3 FAF2 0 0 0 153 1 1
ORMDL3 WDR66 0 0 113 178 1 1
ORMDL3 FADS1 0 0 160 229 1 1
ORMDL3 PLA2G12B 0 0 0 323 1 1
ORMDL3 OSBPL10 0 0 113 403 1 1
ORMDL3 THSD4 0 0 210 210 1 1
ORMDL3 CWF19L2 0 0 233 570 1 1
ORMDL3 KHNYN 0 0 74 154 1 1
ORMDL3 STARD3 0 0 378 449 1 1
ORMDL3 SGK1 0 0 55 273 1 2
ORMDL3 ADRB2 0 0 324 323 1 1
ORMDL3 RPS6KB1 0 0 0 262 1 2
ORMDL3 GADL1 0 0 0 176 1 1
ORMDL3 C11orf71 0 0 166 165 1 1
ORMDL3 INS-IGF2 0 0 167 167 1 1
ORMDL3 PRKAA1 0 0 0 320 1 2
ORMDL3 REEP3 0 0 180 179 1 1
ORMDL3 DENND1B 0 0 710 760 1 1
ORMDL3 TRH 0 0 45 473 1 1
ORMDL3 SPTLC2 0 900 469 969 1 1
ORMDL3 EQTN 0 0 325 325 1 1
ORMDL3 STIM1 0 0 115 180 1 2
ORMDL3 RNF186 0 0 234 234 1 1
Ontologies
ID Category Term Effect Evidence PubMed
GO:0005515 Molecular Function protein binding enables IPI
GO:0006672 Biological Process ceramide metabolic process involved_in IBA
GO:0006672 Biological Process ceramide metabolic process involved_in IMP
GO:0090156 Biological Process intracellular sphingolipid homeostasis involved_in IBA
GO:0061744 Biological Process motor behavior involved_in IEA
GO:0042552 Biological Process myelination involved_in IEA
GO:0002903 Biological Process negative regulation of B cell apoptotic process acts_upstream_of_or_within IMP
GO:1900060 Biological Process negative regulation of ceramide biosynthetic process acts_upstream_of_or_within IMP
GO:0010508 Biological Process positive regulation of autophagy acts_upstream_of_or_within IDA
GO:0010508 Biological Process positive regulation of autophagy acts_upstream_of_or_within IMP
GO:1900182 Biological Process positive regulation of protein localization to nucleus acts_upstream_of_or_within IDA
GO:0006940 Biological Process regulation of smooth muscle contraction involved_in IEA
GO:0030148 Biological Process sphingolipid biosynthetic process involved_in IBA
GO:0006686 Biological Process sphingomyelin biosynthetic process involved_in IEA
GO:0035339 Cellular Component SPOTS complex part_of IBA
GO:0035339 Cellular Component SPOTS complex part_of IDA
GO:0005783 Cellular Component endoplasmic reticulum located_in IDA
GO:0005789 Cellular Component endoplasmic reticulum membrane located_in IEA
GO:0005886 Cellular Component plasma membrane located_in TAS
GO:0030667 Cellular Component secretory granule membrane located_in TAS
GO:0035579 Cellular Component specific granule membrane located_in TAS
Pathways
Name DB ID
Metabolism Reactome R-HSA-1430728
Sphingolipid de novo biosynthesis Reactome R-HSA-1660661
Innate Immune System Reactome R-HSA-168249
Immune System Reactome R-HSA-168256
Sphingolipid metabolism Reactome R-HSA-428157
Metabolism of lipids Reactome R-HSA-556833
Neutrophil degranulation Reactome R-HSA-6798695
Transcripts
Accession Version MolecularType Name NCBI Comments
XM_047437093 1 mRNA transcript variant X1 NC_000017 Reference
XM_047437094 1 mRNA transcript variant X3 NC_000017 Reference
XM_047437095 1 mRNA transcript variant X2 NC_000017 Reference
NM_001320803 1 mRNA transcript variant 4 NC_000017 Reference
NM_001320802 2 mRNA transcript variant 3 NC_000017 Reference
NM_139280 4 mRNA transcript variant 2 NC_000017 Reference
NM_001320801 2 mRNA transcript variant 1 NC_000017 Reference